Mus musculus

405 known processes

Psen2

presenilin 2

(Aliases: STM2,Alg3,Ad4h,PS2,PS-2,ALG-3,Psnl2)

Psen2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of calcium ion dependent exocytosisGO:004595530.951
response to symbiontGO:000960820.943
lateral inhibitionGO:004633110.919
Fly
negative regulation of blood vessel endothelial cell migrationGO:004353730.809
neuroblast fate determinationGO:000740010.675
growth involved in heart morphogenesisGO:000324140.665
hair cycle phaseGO:0044851160.659
cell migration involved in endocardial cushion formationGO:000327330.634
myeloid dendritic cell activationGO:0001773250.621
Mouse
choline transportGO:001587130.535
Mouse
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.527
regulation of resting membrane potentialGO:006007530.514
Mouse
cardiac right ventricle formationGO:000321930.433
regulation of pro b cell differentiationGO:200097350.418
notch receptor processingGO:000722040.414
Mouse Fly
heart trabecula morphogenesisGO:0061384260.401
cardiac right atrium morphogenesisGO:000321330.398
biological phaseGO:0044848200.365
glial cell fate determinationGO:000740330.360
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.359
regulation of somitogenesisGO:001480760.357
somite specificationGO:000175740.346
i kappab phosphorylationGO:000725260.343
atrioventricular node developmentGO:000316230.312
regulation of epidermal growth factor activated receptor activityGO:000717670.308
beta amyloid metabolic processGO:0050435140.300
myeloid dendritic cell differentiationGO:0043011160.293
Mouse
negative regulation of protein tyrosine kinase activityGO:006109930.244
blood vessel endothelial cell differentiationGO:006083760.243
positive regulation of mesoderm developmentGO:200038220.238
peptide metabolic processGO:0006518460.236
positive regulation of keratinocyte differentiationGO:004561830.236
endoplasmic reticulum calcium ion homeostasisGO:0032469110.217
positive regulation of osteoclast differentiationGO:0045672150.198
protein glycosylationGO:0006486550.196
Mouse
notch signaling pathwayGO:0007219710.194
regulation of extracellular matrix assemblyGO:190120120.192
positive regulation of cell deathGO:00109422240.191
leukocyte differentiationGO:00025213420.190
apoptotic process involved in embryonic digit morphogenesisGO:190226330.187
positive regulation of transcription of notch receptor targetGO:000722140.187
anagenGO:0042640130.186
glomerular mesangial cell differentiationGO:007200830.186
interleukin 4 secretionGO:007260250.183
myeloid leukocyte activationGO:0002274830.183
Mouse
glomerular visceral epithelial cell developmentGO:007201560.182
regulation of epidermal cell differentiationGO:0045604210.182
venous blood vessel morphogenesisGO:004884570.181
amine metabolic processGO:0009308450.171
stem cell fate determinationGO:004886720.171
cytokine productionGO:00018163190.170
negative regulation of cellular amino acid metabolic processGO:004576300.169
negative regulation of fat cell differentiationGO:0045599360.165
cytokine secretionGO:0050663720.164
regulation of secretionGO:00510462740.161
negative regulation of immune system processGO:00026832090.159
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.159
compartment pattern specificationGO:000738640.158
positive regulation of astrocyte differentiationGO:004871180.157
calcium ion dependent exocytosisGO:0017156350.157
negative regulation of hematopoietic progenitor cell differentiationGO:190153340.155
extracellular structure organizationGO:00430621480.154
glomerular mesangial cell developmentGO:007214430.151
negative regulation of endothelial cell migrationGO:001059640.149
limb morphogenesisGO:00351081490.148
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.147
extracellular matrix organizationGO:00301981470.145
glycoprotein biosynthetic processGO:0009101890.145
Mouse
vascular smooth muscle cell differentiationGO:0035886110.140
regulation of cardioblast differentiationGO:005189030.140
compound eye developmentGO:004874910.138
regulation of astrocyte differentiationGO:0048710200.137
divalent inorganic cation transportGO:00725111780.137
neuroblast fate commitmentGO:001401710.136
cation transportGO:00068123990.136
receptor recyclingGO:0001881110.135
anatomical structure maturationGO:0071695490.133
regulation of cellular amino acid metabolic processGO:000652150.133
protein maturationGO:00516041760.132
mesangial cell developmentGO:007214340.130
negative regulation of glial cell proliferationGO:006025340.130
arterial endothelial cell differentiationGO:006084250.127
defense response to other organismGO:00985421970.126
positive regulation of cell cycle g1 s phase transitionGO:190280890.124
somitogenesisGO:0001756690.123
inorganic cation transmembrane transportGO:00986622070.123
cardiac cell fate specificationGO:006091220.120
defense response to bacteriumGO:00427421190.120
placenta blood vessel developmentGO:0060674310.119
calcium ion homeostasisGO:00550741270.119
positive regulation of programmed cell deathGO:00430682180.118
inner ear receptor cell differentiationGO:0060113610.117
mechanoreceptor differentiationGO:0042490670.116
learning or memoryGO:00076111480.116
negative regulation of myotube differentiationGO:001083290.115
transition metal ion transportGO:0000041380.114
Fly
positive regulation of leukocyte differentiationGO:1902107860.114
ossificationGO:00015032160.114
regulation of myeloid leukocyte differentiationGO:0002761580.113
keratinocyte differentiationGO:0030216480.113
regulation of cell migration involved in sprouting angiogenesisGO:009004940.112
protein secretionGO:00093061110.111
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.111
regulation of cellular ketone metabolic processGO:0010565660.111
inflammatory responseGO:00069542440.110
mesangial cell differentiationGO:007200740.108
carbohydrate derivative biosynthetic processGO:19011371830.108
Mouse
i kappab kinase nf kappab signalingGO:0007249850.108
positive regulation of myeloid leukocyte differentiationGO:0002763260.108
kidney developmentGO:00018222130.107
response to organonitrogen compoundGO:00102432460.107
regulation of receptor recyclingGO:000191980.107
positive regulation of apoptotic processGO:00430652170.106
mesenchyme developmentGO:00604851520.105
cellular amide metabolic processGO:0043603580.105
calcium ion transportGO:00068161590.104
vascular smooth muscle cell developmentGO:009708470.104
negative regulation of photoreceptor cell differentiationGO:004653340.101
regulation of mitotic cell cycle phase transitionGO:1901990730.101
hematopoietic progenitor cell differentiationGO:00022441430.101
pharynx developmentGO:006046510.100
photoreceptor cell differentiationGO:0046530520.099
negative regulation of glial cell differentiationGO:0045686210.098
transmembrane transportGO:00550854120.097
sensory organ boundary specificationGO:000805210.095
beta amyloid formationGO:003420590.095
Mouse
modification dependent macromolecule catabolic processGO:00436321330.094
developmental maturationGO:00217001930.094
mitotic cell cycleGO:00002781950.094
formation of organ boundaryGO:001016010.092
ventricular trabecula myocardium morphogenesisGO:0003222110.092
inorganic ion transmembrane transportGO:00986602340.092
protein processingGO:00164851630.090
positive regulation of apoptotic signaling pathwayGO:2001235950.090
negative regulation of exocytosisGO:0045920120.089
negative regulation of osteoblast differentiationGO:0045668300.087
regulation of keratinocyte differentiationGO:0045616110.087
myeloid leukocyte differentiationGO:00025731190.086
regulation of leukocyte differentiationGO:19021051590.086
embryonic limb morphogenesisGO:00303261260.086
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.085
response to peptideGO:19016521360.084
immune effector processGO:00022523210.084
glomerulus morphogenesisGO:0072102100.084
negative regulation of endothelial cell differentiationGO:004560220.083
immune response activating signal transductionGO:00027571160.083
neurotransmitter secretionGO:0007269620.083
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.083
t cell activationGO:00421102890.082
cell cell signaling involved in cell fate commitmentGO:0045168350.082
Fly
limb developmentGO:00601731660.081
appendage developmentGO:00487361660.081
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.080
glycoprotein metabolic processGO:00091001160.080
Mouse
ion transmembrane transportGO:00342203610.079
myeloid cell differentiationGO:00300992330.078
muscle tissue developmentGO:00605373080.078
myotube differentiationGO:00149021050.077
circulatory system processGO:00030131970.077
regulation of cardiac cell fate specificationGO:200004310.076
swimming behaviorGO:003626910.076
glomerulus developmentGO:0032835400.076
regulation of osteoclast differentiationGO:0045670360.076
long term memoryGO:0007616150.075
divalent inorganic cation homeostasisGO:00725071380.074
embryonic digit morphogenesisGO:0042733560.074
membrane protein proteolysisGO:0033619100.073
Human
photoreceptor cell morphogenesisGO:000859430.073
aortic valve morphogenesisGO:000318040.073
negative regulation of cell developmentGO:00107211690.073
Mouse
memoryGO:0007613580.073
positive regulation of cell cycle phase transitionGO:1901989170.073
glycosylationGO:0070085620.073
Mouse
positive regulation of homeostatic processGO:0032846640.073
endothelial tube morphogenesisGO:006115420.073
forebrain developmentGO:00309003020.072
glomerular epithelial cell developmentGO:007231060.071
cell fate determination involved in pattern specificationGO:006058210.071
exocytosisGO:00068871210.071
Mouse
regulation of secretion by cellGO:19035302490.070
epidermis developmentGO:00085441870.070
negative regulation of molecular functionGO:00440922580.070
embryonic organ morphogenesisGO:00485622760.070
Mouse
prostate glandular acinus developmentGO:0060525120.070
positive regulation of notch signaling pathwayGO:0045747180.069
cardiac vascular smooth muscle cell developmentGO:006094830.068
regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006141820.068
cellular amino acid metabolic processGO:00065201030.068
regulation of mitotic cell cycleGO:00073461260.067
regulation of membrane potentialGO:00423911920.067
Mouse
striated muscle tissue developmentGO:00147062930.067
meiotic nuclear divisionGO:00071261150.066
heart processGO:0003015940.066
positive regulation of myeloid cell differentiationGO:0045639430.066
meiotic cell cycleGO:00513211220.065
proximal tubule developmentGO:007201450.065
humoral immune responseGO:0006959570.065
negative regulation of oligodendrocyte differentiationGO:0048715110.064
cation homeostasisGO:00550802120.064
regulation of calcium ion dependent exocytosisGO:0017158160.064
ciliary body morphogenesisGO:006107330.063
negative regulation of striated muscle cell differentiationGO:0051154140.063
regulation of neuron differentiationGO:00456642810.063
Mouse
regulation of filopodium assemblyGO:0051489130.063
cellular lipid metabolic processGO:00442553230.063
myoblast differentiationGO:0045445520.063
homeostasis of number of cellsGO:00488722100.062
negative regulation of anoikisGO:200081120.062
neuroblast differentiationGO:001401620.062
organic hydroxy compound transportGO:0015850930.061
Mouse
angiogenesisGO:00015252010.061
cell cell adhesionGO:0098609410.061
epithelial cell proliferationGO:00506731740.060
Mouse
regulation of myotube differentiationGO:0010830620.060
activation of immune responseGO:00022531380.060
muscle system processGO:00030121410.060
ubiquitin dependent protein catabolic processGO:00065111290.059
endothelium developmentGO:0003158450.059
protein modification by small protein conjugation or removalGO:00706472070.059
gland developmentGO:00487323300.059
response to growth factorGO:00708481980.059
segment specificationGO:0007379150.059
cardiac chamber developmentGO:00032051080.059
notch signaling involved in heart developmentGO:006131450.058
inflammatory response to antigenic stimulusGO:0002437300.058
hair follicle developmentGO:0001942850.058
cell type specific apoptotic processGO:00972852680.058
Mouse
autophagyGO:0006914450.058
Mouse
regulation of cell cycle phase transitionGO:1901987770.057
organelle assemblyGO:00709251770.057
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.056
coronary vein morphogenesisGO:000316920.056
cellular calcium ion homeostasisGO:00068741190.055
cellular response to inorganic substanceGO:0071241370.055
negative regulation of ubiquitin protein transferase activityGO:005144430.055
glomerular capillary formationGO:007210460.055
cation transmembrane transportGO:00986552660.055
renal system vasculature developmentGO:0061437150.055
cellular amine metabolic processGO:0044106440.054
response to oxygen levelsGO:0070482620.054
spermatogenesisGO:00072832840.054
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.054
cell fate commitment involved in pattern specificationGO:0060581140.054
acidic amino acid transportGO:0015800160.054
Mouse
placenta developmentGO:00018901400.053
auditory receptor cell differentiationGO:0042491370.053
epithelial tube morphogenesisGO:00605623030.053
Mouse
regulation of meiotic cell cycleGO:0051445340.053
morphogenesis of an endotheliumGO:000315920.053
skeletal muscle fiber developmentGO:0048741580.052
peptidyl amino acid modificationGO:00181933360.052
cellular ketone metabolic processGO:0042180840.052
protein ubiquitinationGO:00165671710.052
cellular chemical homeostasisGO:00550822150.052
canonical wnt signaling pathwayGO:00600701300.052
regulation of neurotransmitter levelsGO:0001505870.052
Mouse
macromolecule catabolic processGO:00090572810.051
regulation of endothelial cell chemotaxisGO:200102610.051
bmp signaling pathwayGO:0030509930.051
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325660.051
regulation of cell projection assemblyGO:0060491380.051
segmentationGO:0035282930.050
response to oxidative stressGO:00069791230.050
Mouse
regulation of exocytosisGO:0017157610.050
cognitionGO:00508901490.049
negative regulation of receptor activityGO:200027250.049
regulation of nuclear divisionGO:0051783560.048
regulation of auditory receptor cell differentiationGO:004560740.048
activation of mapkk activityGO:0000186150.048
Mouse
negative regulation of secretionGO:0051048610.048
immune response activating cell surface receptor signaling pathwayGO:0002429720.048
positive regulation of proteolysisGO:0045862850.048
interleukin 4 productionGO:0032633240.048
carbohydrate metabolic processGO:00059752300.048
Mouse
positive regulation of mitotic cell cycle phase transitionGO:1901992170.047
regulation of myeloid cell differentiationGO:0045637960.047
cellular homeostasisGO:00197252400.047
muscle cell developmentGO:00550011330.047
regulation of ossificationGO:00302781120.047
embryonic appendage morphogenesisGO:00351131260.047
negative regulation of ossificationGO:0030279490.047
lymphocyte activation involved in immune responseGO:0002285930.047
regulation of organelle organizationGO:00330432890.046
response to hypoxiaGO:0001666580.046
rhombomere morphogenesisGO:002159320.046
blood vessel morphogenesisGO:00485142850.046
response to decreased oxygen levelsGO:0036293590.046
lung developmentGO:00303241640.046
positive regulation of cellular catabolic processGO:00313311480.045
regulation of hematopoietic progenitor cell differentiationGO:1901532180.045
positive regulation of glial cell differentiationGO:0045687210.045
positive regulation of epidermal cell differentiationGO:004560660.045
organonitrogen compound biosynthetic processGO:19015661920.045
muscle cell differentiationGO:00426922610.044
response to muramyl dipeptideGO:003249590.044
organelle fissionGO:00482851700.044
cellular response to dna damage stimulusGO:00069742070.044
Mouse
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:0007157200.044
heart contractionGO:0060047930.044
respiratory system developmentGO:00605411900.044
kidney vasculature developmentGO:0061440150.043
somite developmentGO:0061053810.043
venous blood vessel developmentGO:0060841130.043
regulation of glial cell differentiationGO:0045685410.043
immune response regulating signaling pathwayGO:00027641250.043
negative regulation of protein processingGO:0010955790.043
apoptotic process involved in morphogenesisGO:0060561250.042
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361880.042
osteoclast differentiationGO:0030316620.042
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.042
response to organic cyclic compoundGO:00140701980.042
negative regulation of secretion by cellGO:1903531540.041
rhombomere formationGO:002159410.041
response to inorganic substanceGO:0010035960.041
cellular protein catabolic processGO:00442571550.040
heart morphogenesisGO:00030071780.040
Mouse
regulation of cell cycle processGO:00105641600.040
regulation of gliogenesisGO:0014013500.040
cardiac left ventricle morphogenesisGO:000321490.040
hair follicle morphogenesisGO:0031069290.040
chemotaxisGO:00069352470.040
cellular response to starvationGO:0009267570.040
Mouse
modification dependent protein catabolic processGO:00199411330.039
ovulation cycleGO:0042698590.039
cellular response to hormone stimulusGO:00328701500.039
regulation of blood vessel endothelial cell migrationGO:0043535120.039
peptidyl tyrosine modificationGO:00182121450.039
positive regulation of cell developmentGO:00107202370.039
hair cell differentiationGO:0035315400.039
positive regulation of mitotic cell cycleGO:0045931410.039
mapk cascadeGO:00001652810.038
Mouse
positive regulation of cell motilityGO:20001471160.038
negative regulation of cellular protein metabolic processGO:00322692470.038
protein modification by small protein conjugationGO:00324461870.038
stem cell maintenanceGO:00198271300.038
regulation of dna templated transcription in response to stressGO:004362090.038
cellular response to gonadotropin stimulusGO:007137140.038
regulation of cell cycleGO:00517262810.038
myotube cell developmentGO:0014904600.038
regulation of cell morphogenesis involved in differentiationGO:00107691510.037
Mouse
regulation of organ morphogenesisGO:20000271440.037
endocytosisGO:00068971680.037
positive regulation of cell migrationGO:00303351090.037
calcium ion transmembrane transportGO:0070588850.037
metal ion homeostasisGO:00550651890.036
regulation of anoikisGO:200020920.036
chromatin organizationGO:00063252060.036
digestive system developmentGO:00551232000.036
regulation of cellular amine metabolic processGO:0033238200.036
hair cycleGO:0042633900.036
regulation of osteoblast differentiationGO:0045667670.036
regulation of oligodendrocyte differentiationGO:0048713230.036
cardiac conduction system developmentGO:0003161120.036
multi multicellular organism processGO:00447061090.036
cardiac muscle tissue developmentGO:00487381300.036
regulation of protein kinase activityGO:00458592320.036
cellular response to external stimulusGO:0071496880.036
Mouse
nuclear divisionGO:00002801580.036
blood vessel lumenizationGO:007255420.036
nucleobase containing small molecule metabolic processGO:00550863520.035
response to lipopolysaccharideGO:00324961280.035
response to nutrient levelsGO:00316671090.035
Mouse
wound healingGO:00420601570.035
inner ear receptor cell fate commitmentGO:006012060.035
sulfur compound metabolic processGO:00067901000.035
urogenital system developmentGO:00016552610.035
response to molecule of bacterial originGO:00022371430.035
regulation of canonical wnt signaling pathwayGO:0060828820.035
kidney vasculature morphogenesisGO:006143970.035
digestive tract developmentGO:00485651900.035
regulation of body fluid levelsGO:00508781620.035
camera type eye developmentGO:00430102660.034
sprouting angiogenesisGO:0002040260.034
regulation of cellular catabolic processGO:00313292420.034
actin cytoskeleton organizationGO:00300362200.034
regulation of g1 s transition of mitotic cell cycleGO:2000045350.034
cellular response to decreased oxygen levelsGO:0036294180.034
cardiac chamber morphogenesisGO:0003206930.034
female gamete generationGO:0007292740.034
regulation of bindingGO:00510981110.033
positive regulation of nervous system developmentGO:00519622210.033
renal tubule developmentGO:0061326870.033
positive regulation of epithelial to mesenchymal transitionGO:0010718130.032
cell chemotaxisGO:0060326810.032
myeloid cell homeostasisGO:00022621140.032
lymphocyte differentiationGO:00300982420.032
nitrogen compound transportGO:00717052710.032
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510901060.032
regulation of chemotaxisGO:0050920530.032
macromolecule glycosylationGO:0043413550.032
Mouse
regulation of proteolysisGO:00301621640.032
epidermis morphogenesisGO:0048730330.032
anatomical structure homeostasisGO:00602491450.032
positive regulation of cellular amine metabolic processGO:003324050.032
negative regulation of nervous system developmentGO:00519611560.032
Mouse
photoreceptor cell developmentGO:0042461400.032
t cell activation involved in immune responseGO:0002286430.032
l amino acid transportGO:0015807320.032
Mouse
leukocyte activation involved in immune responseGO:00023661260.032
positive regulation of cytokine productionGO:00018191740.031
regulation of establishment of protein localizationGO:00702011810.031
male gamete generationGO:00482322850.031
cellular response to metal ionGO:0071248310.031
proteolysis involved in cellular protein catabolic processGO:00516031470.031
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.031
developmental programmed cell deathGO:0010623410.031
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.031
multi organism behaviorGO:0051705620.031
innate immune responseGO:00450871570.031
regulation of synaptic transmission glutamatergicGO:0051966190.031
Mouse
g1 s transition of mitotic cell cycleGO:0000082570.031
reactive oxygen species metabolic processGO:0072593840.031
anion transportGO:00068201770.031
Mouse
negative regulation of proteolysisGO:0045861740.031
negative regulation of protein maturationGO:1903318790.031
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.031
cardiac ventricle developmentGO:0003231830.031
positive regulation of hydrolase activityGO:00513451480.030
thymus developmentGO:0048538410.030
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.030
striated muscle contractionGO:0006941450.030
regulation of muscle tissue developmentGO:1901861970.030
regulation of fat cell differentiationGO:0045598810.030
appendage morphogenesisGO:00351071490.030
regulation of cell migrationGO:00303342190.030
glomerulus vasculature developmentGO:0072012140.030
neural precursor cell proliferationGO:00613511210.029
wnt signaling pathwayGO:00160551880.029
negative regulation of neuron differentiationGO:00456651010.029
Mouse
leukocyte proliferationGO:00706611720.029
regulation of retina development in camera type eyeGO:190286630.029
negative regulation of muscle cell differentiationGO:0051148330.029
cellular response to oxygen levelsGO:0071453200.029
cardiac septum developmentGO:0003279590.029
determination of left right symmetryGO:0007368800.029
Mouse
cardiocyte differentiationGO:0035051870.029
oligodendrocyte differentiationGO:0048709530.029
cell activation involved in immune responseGO:00022631260.029
regulation of homeostatic processGO:00328441820.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.029
regulation of epidermis developmentGO:0045682330.028
embryonic hemopoiesisGO:0035162230.028
female sex differentiationGO:0046660840.028
epithalamus developmentGO:002153820.028
spinal cord developmentGO:0021510810.028
regulation of epithelial cell proliferation involved in prostate gland developmentGO:0060768100.028
regulation of neural retina developmentGO:006107430.028
peripheral nervous system developmentGO:0007422530.028
cell substrate adhesionGO:00315891300.028
macromolecule methylationGO:00434141200.028
cardiac endothelial cell differentiationGO:000334840.027
protein catabolic processGO:00301632210.027
blood circulationGO:00080151950.027
endothelial cell differentiationGO:0045446410.027
negative regulation of gliogenesisGO:0014014230.027
regulation of vesicle mediated transportGO:00606271390.027
positive regulation of cell cycle processGO:0090068610.027
epithelium migrationGO:0090132630.027
regulation of endocytosisGO:0030100690.027
positive regulation of cell fate commitmentGO:001045580.027
neuron apoptotic processGO:00514021420.026
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.026
neuron deathGO:00709971540.026
Mouse
fat cell differentiationGO:00454441600.026
epithelial cell developmentGO:00020641590.026
regulation of notch signaling pathwayGO:0008593350.026
Fly
nephron tubule developmentGO:0072080840.026
cellular response to growth factor stimulusGO:00713631970.026
odontogenesisGO:0042476780.026
positive regulation of secretionGO:00510471300.026
hindlimb morphogenesisGO:0035137420.026
cellular metal ion homeostasisGO:00068751510.026
negative regulation of cell cycleGO:00457861230.025
posttranscriptional regulation of gene expressionGO:00106081550.025
muscle fiber developmentGO:0048747760.025
mitral valve developmentGO:000317440.025

Psen2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.454
Human
heart diseaseDOID:11400.454
Human
cardiovascular system diseaseDOID:128700.454
Human
central nervous system diseaseDOID:33100.234
Human
nervous system diseaseDOID:86300.234
Human
disease of mental healthDOID:15000.232
Human
cognitive disorderDOID:156100.232
Human
musculoskeletal system diseaseDOID:1700.189
Human
myopathyDOID:42300.189
Human
muscular diseaseDOID:008000000.189
Human
cardiomyopathyDOID:005070000.189
Human
muscle tissue diseaseDOID:6600.189
Human
integumentary system diseaseDOID:1600.154
skin diseaseDOID:3700.154
dementiaDOID:130700.118
Human
neurodegenerative diseaseDOID:128900.107
Human
intrinsic cardiomyopathyDOID:006003600.097
Human
tauopathyDOID:68000.075
Human
alzheimer s diseaseDOID:1065200.075
Human
disease of metabolismDOID:001466700.039
inherited metabolic disorderDOID:65500.027
brain diseaseDOID:93600.027
gastrointestinal system diseaseDOID:7700.026