IMP: Integrative Multi-species Prediction

Mus musculus

9 known processes

Lztfl1

leucine zipper transcription factor-like 1

(Aliases: AW048545,AI414725,5530402H04Rik,MGC106871,6130400H19Rik)

Entrez: 93730
Ensembl: ENSMUSG00000025245
UniProtKB: Q9JHQ5

Process Predictions
Disease Predictions

Lztfl1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cilium morphogenesis	GO:0060271	102	0.070
cilium assembly	GO:0042384	81	0.068
spermatogenesis	GO:0007283	284	0.033
cellular component assembly involved in morphogenesis	GO:0010927	139	0.032
purine nucleotide metabolic process	GO:0006163	302	0.032
protein catabolic process	GO:0030163	221	0.029
camera type eye development	GO:0043010	266	0.026
organelle assembly	GO:0070925	177	0.025
membrane organization	GO:0061024	245	0.024
forebrain development	GO:0030900	302	0.024
organophosphate catabolic process	GO:0046434	232	0.024
cytoskeleton dependent intracellular transport	GO:0030705	50	0.024
retina development in camera type eye	GO:0060041	119	0.024
male gamete generation	GO:0048232	285	0.023
protein modification by small protein conjugation or removal	GO:0070647	207	0.023
cellular protein catabolic process	GO:0044257	155	0.021
glycosyl compound metabolic process	GO:1901657	246	0.021
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.021
purine ribonucleotide catabolic process	GO:0009154	208	0.021
cell type specific apoptotic process	GO:0097285	268	0.021
sensory organ morphogenesis	GO:0090596	242	0.021
neural tube development	GO:0021915	160	0.021
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.020
fat cell differentiation	GO:0045444	160	0.020
protein ubiquitination	GO:0016567	171	0.020
purine containing compound metabolic process	GO:0072521	311	0.020
cellular nitrogen compound catabolic process	GO:0044270	280	0.020
rho protein signal transduction	GO:0007266	32	0.020
spermatid development	GO:0007286	108	0.020
regulation of cellular amine metabolic process	GO:0033238	20	0.020
ribonucleoside catabolic process	GO:0042454	206	0.019
sensory perception	GO:0007600	245	0.019
transmembrane transport	GO:0055085	412	0.019
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.019
small gtpase mediated signal transduction	GO:0007264	97	0.019
dna metabolic process	GO:0006259	303	0.019
cellular homeostasis	GO:0019725	240	0.019
nucleoside triphosphate catabolic process	GO:0009143	205	0.018
nucleoside triphosphate metabolic process	GO:0009141	230	0.018
regulation of cell motility	GO:2000145	236	0.018
purine ribonucleotide metabolic process	GO:0009150	290	0.018
regulation of cellular amino acid metabolic process	GO:0006521	5	0.018
nucleoside metabolic process	GO:0009116	246	0.018
nucleoside phosphate metabolic process	GO:0006753	338	0.018
regulation of cellular ketone metabolic process	GO:0010565	66	0.018
skeletal system development	GO:0001501	356	0.017
organic cyclic compound catabolic process	GO:1901361	295	0.017
proteasomal protein catabolic process	GO:0010498	98	0.017
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.017
cytoplasmic transport	GO:0016482	234	0.017
cellular amine metabolic process	GO:0044106	44	0.017
cation transport	GO:0006812	399	0.017
nucleotide catabolic process	GO:0009166	217	0.017
cellular ketone metabolic process	GO:0042180	84	0.017
regulation of protein localization	GO:0032880	231	0.017
carbohydrate derivative catabolic process	GO:1901136	231	0.016
purine nucleotide catabolic process	GO:0006195	211	0.016
intraciliary transport	GO:0042073	9	0.016
nucleoside phosphate catabolic process	GO:1901292	222	0.016
microtubule based movement	GO:0007018	84	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.016
muscle tissue development	GO:0060537	308	0.016
purine containing compound catabolic process	GO:0072523	213	0.016
purine ribonucleoside catabolic process	GO:0046130	205	0.016
purine ribonucleoside metabolic process	GO:0046128	241	0.016
ribose phosphate metabolic process	GO:0019693	291	0.016
modification dependent protein catabolic process	GO:0019941	133	0.016
ribonucleotide catabolic process	GO:0009261	208	0.016
cellular amino acid metabolic process	GO:0006520	103	0.016
aromatic compound catabolic process	GO:0019439	286	0.016
telencephalon development	GO:0021537	186	0.015
ribonucleoside metabolic process	GO:0009119	245	0.015
nucleobase containing small molecule metabolic process	GO:0055086	352	0.015
modification dependent macromolecule catabolic process	GO:0043632	133	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.015
amine metabolic process	GO:0009308	45	0.015
primary neural tube formation	GO:0014020	95	0.015
nucleotide metabolic process	GO:0009117	332	0.015
purine nucleoside metabolic process	GO:0042278	241	0.015
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.015
negative regulation of protein metabolic process	GO:0051248	282	0.015
microtubule based transport	GO:0010970	50	0.015
microtubule based process	GO:0007017	236	0.015
regulation of cell projection organization	GO:0031344	206	0.015
skeletal muscle organ development	GO:0060538	163	0.014
purine nucleoside catabolic process	GO:0006152	205	0.014
ribonucleotide metabolic process	GO:0009259	291	0.014
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.014
muscle cell differentiation	GO:0042692	261	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.014
glycosyl compound catabolic process	GO:1901658	206	0.014
adult behavior	GO:0030534	135	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
protein localization to organelle	GO:0033365	185	0.014
heterocycle catabolic process	GO:0046700	280	0.014
positive regulation of cellular amine metabolic process	GO:0033240	5	0.014
regulation of purine nucleotide metabolic process	GO:1900542	169	0.014
protein modification by small protein conjugation	GO:0032446	187	0.014
eye photoreceptor cell differentiation	GO:0001754	41	0.014
negative regulation of molecular function	GO:0044092	258	0.014
protein processing	GO:0016485	163	0.013
nucleoside catabolic process	GO:0009164	206	0.013
organelle localization	GO:0051640	179	0.013
tube formation	GO:0035148	140	0.013
negative regulation of cellular protein metabolic process	GO:0032269	247	0.013
cation transmembrane transport	GO:0098655	266	0.013
protein maturation	GO:0051604	176	0.013
cellular macromolecule catabolic process	GO:0044265	206	0.013
negative regulation of cell proliferation	GO:0008285	296	0.013
positive regulation of cell development	GO:0010720	237	0.013
positive regulation of protein modification process	GO:0031401	299	0.013
carbohydrate derivative biosynthetic process	GO:1901137	183	0.013
intracellular protein transport	GO:0006886	204	0.013
endomembrane system organization	GO:0010256	147	0.012
organonitrogen compound catabolic process	GO:1901565	264	0.012
posttranscriptional regulation of gene expression	GO:0010608	155	0.012
carbohydrate homeostasis	GO:0033500	128	0.012
protein localization to membrane	GO:0072657	108	0.012
epithelial tube formation	GO:0072175	130	0.012
nitrogen compound transport	GO:0071705	271	0.012
regulation of protein catabolic process	GO:0042176	108	0.012
regulation of cellular component biogenesis	GO:0044087	181	0.012
glucose homeostasis	GO:0042593	128	0.012
positive regulation of organelle organization	GO:0010638	128	0.011
cognition	GO:0050890	149	0.011
renal system development	GO:0072001	225	0.011
regulation of intracellular transport	GO:0032386	159	0.011
negative regulation of cellular component organization	GO:0051129	194	0.011
positive regulation of hydrolase activity	GO:0051345	148	0.011
positive regulation of cellular catabolic process	GO:0031331	148	0.011
ubiquitin dependent protein catabolic process	GO:0006511	129	0.011
cellular response to organonitrogen compound	GO:0071417	145	0.011
urogenital system development	GO:0001655	261	0.011
divalent metal ion transport	GO:0070838	172	0.011
positive regulation of nervous system development	GO:0051962	221	0.011
epithelial tube morphogenesis	GO:0060562	303	0.011
regulation of nucleoside metabolic process	GO:0009118	130	0.011
divalent inorganic cation transport	GO:0072511	178	0.011
regulation of vesicle mediated transport	GO:0060627	139	0.011
retina morphogenesis in camera type eye	GO:0060042	45	0.011
positive regulation of cell projection organization	GO:0031346	95	0.011
glycoprotein metabolic process	GO:0009100	116	0.011
cellular response to hormone stimulus	GO:0032870	150	0.011
macromolecule catabolic process	GO:0009057	281	0.011
regulation of nucleotide metabolic process	GO:0006140	169	0.010
maintenance of location	GO:0051235	89	0.010
spermatid differentiation	GO:0048515	115	0.010
blood circulation	GO:0008015	195	0.010
response to extracellular stimulus	GO:0009991	127	0.010
anatomical structure homeostasis	GO:0060249	145	0.010

Lztfl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.018
nervous system disease	DOID:863	0.018
immune system disease	DOID:2914	0.017
cancer	DOID:162	0.017
disease of cellular proliferation	DOID:14566	0.017
organ system cancer	DOID:0050686	0.016
eye and adnexa disease	DOID:1492	0.014
retinal disease	DOID:5679	0.014
sensory system disease	DOID:0050155	0.014
eye disease	DOID:5614	0.014
retinal degeneration	DOID:8466	0.012

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