Mus musculus

2 known processes

Pla1a

phospholipase A1 member A

(Aliases: AA986889,Pspla1,Ps-pla1)

Pla1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune effector processGO:00022523210.080
cytokine productionGO:00018163190.070
purine containing compound metabolic processGO:00725213110.063
regulation of cytokine productionGO:00018172660.059
cellular ketone metabolic processGO:0042180840.059
cellular amino acid metabolic processGO:00065201030.058
regulation of cellular ketone metabolic processGO:0010565660.058
angiogenesisGO:00015252010.057
cellular lipid metabolic processGO:00442553230.056
regulation of cellular amine metabolic processGO:0033238200.050
myeloid cell differentiationGO:00300992330.049
cation homeostasisGO:00550802120.048
lipid biosynthetic processGO:00086101790.048
regulation of defense responseGO:00313472330.047
cation transportGO:00068123990.047
negative regulation of molecular functionGO:00440922580.045
cell adhesionGO:00071553290.043
negative regulation of protein metabolic processGO:00512482820.042
cellular amine metabolic processGO:0044106440.041
positive regulation of cd4 positive alpha beta t cell proliferationGO:200056310.041
chemotaxisGO:00069352470.039
amine metabolic processGO:0009308450.037
anion transportGO:00068201770.037
regulation of hydrolase activityGO:00513362460.037
oxidation reduction processGO:00551143420.036
nucleobase containing small molecule metabolic processGO:00550863520.036
nucleoside phosphate metabolic processGO:00067533380.036
nucleotide metabolic processGO:00091173320.036
blood vessel morphogenesisGO:00485142850.035
cellular ion homeostasisGO:00068731650.034
glycosyl compound metabolic processGO:19016572460.034
epithelial tube morphogenesisGO:00605623030.033
regulation of cellular amino acid metabolic processGO:000652150.033
cellular homeostasisGO:00197252400.033
defense response to other organismGO:00985421970.032
purine nucleotide metabolic processGO:00061633020.032
organic cyclic compound catabolic processGO:19013612950.031
negative regulation of cellular protein metabolic processGO:00322692470.031
nitrogen compound transportGO:00717052710.030
transmembrane transportGO:00550854120.030
regulation of cellular component biogenesisGO:00440871810.030
reactive oxygen species metabolic processGO:0072593840.030
glycoprotein biosynthetic processGO:0009101890.030
purine ribonucleoside triphosphate metabolic processGO:00092052200.029
regulation of angiogenesisGO:0045765810.029
nucleoside triphosphate catabolic processGO:00091432050.029
regulation of establishment of protein localizationGO:00702011810.029
regulation of mapk cascadeGO:00434082480.028
purine ribonucleotide metabolic processGO:00091502900.028
leukocyte mediated immunityGO:00024431740.028
protein maturationGO:00516041760.028
small gtpase mediated signal transductionGO:0007264970.027
positive regulation of protein modification processGO:00314012990.027
positive regulation of cellular amine metabolic processGO:003324050.027
organic acid biosynthetic processGO:0016053860.027
cell substrate adhesionGO:00315891300.027
regulation of secretionGO:00510462740.027
carbohydrate derivative biosynthetic processGO:19011371830.027
mapk cascadeGO:00001652810.027
regulation of endopeptidase activityGO:0052548890.026
regulation of hormone levelsGO:00108172110.026
regulation of cellular catabolic processGO:00313292420.026
regulation of cell migrationGO:00303342190.026
regulation of inflammatory responseGO:00507271470.026
response to molecule of bacterial originGO:00022371430.026
homeostasis of number of cellsGO:00488722100.026
response to peptideGO:19016521360.026
carbohydrate metabolic processGO:00059752300.026
regulation of cell adhesionGO:00301551540.025
negative regulation of endopeptidase activityGO:0010951440.025
divalent inorganic cation transportGO:00725111780.025
ribonucleotide metabolic processGO:00092592910.024
positive regulation of protein phosphorylationGO:00019342420.024
rho protein signal transductionGO:0007266320.024
ion transmembrane transportGO:00342203610.024
muscle tissue developmentGO:00605373080.024
regulation of nucleotide metabolic processGO:00061401690.024
regulation of cell activationGO:00508652890.024
fat cell differentiationGO:00454441600.023
purine ribonucleotide catabolic processGO:00091542080.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
purine ribonucleoside catabolic processGO:00461302050.023
cellular nitrogen compound catabolic processGO:00442702800.023
aromatic compound catabolic processGO:00194392860.023
response to organonitrogen compoundGO:00102432460.023
organic anion transportGO:00157111370.023
ribose phosphate metabolic processGO:00196932910.023
leukocyte differentiationGO:00025213420.023
heterocycle catabolic processGO:00467002800.022
positive regulation of cell deathGO:00109422240.022
positive regulation of immunoglobulin production in mucosal tissueGO:200055810.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
extracellular matrix organizationGO:00301981470.022
ras protein signal transductionGO:0007265770.022
regulation of vasculature developmentGO:1901342880.022
divalent metal ion transportGO:00708381720.022
cell chemotaxisGO:0060326810.022
positive regulation of monocyte chemotaxisGO:009002620.022
mature dendritic cell differentiationGO:009702930.022
organic hydroxy compound metabolic processGO:19016152030.022
steroid metabolic processGO:00082021190.022
regulation of transferase activityGO:00513382630.022
spermatogenesisGO:00072832840.022
fatty acid metabolic processGO:00066311210.022
positive regulation of transferase activityGO:00513471670.022
small molecule biosynthetic processGO:00442831320.022
sequestering of metal ionGO:0051238190.022
apoptotic signaling pathwayGO:00971903060.021
immunoglobulin mediated immune responseGO:0016064690.021
nucleoside catabolic processGO:00091642060.021
protein processingGO:00164851630.021
ribonucleoside metabolic processGO:00091192450.021
positive regulation of cytokine productionGO:00018191740.021
glycoprotein metabolic processGO:00091001160.021
regulation of lymphocyte proliferationGO:00506701170.021
cellular metal ion homeostasisGO:00068751510.021
purine containing compound catabolic processGO:00725232130.021
ribonucleotide catabolic processGO:00092612080.021
lymphocyte proliferationGO:00466511640.021
regulation of organelle organizationGO:00330432890.021
wound healingGO:00420601570.021
striated muscle tissue developmentGO:00147062930.021
morphogenesis of a branching epitheliumGO:00611381930.021
regulation of protein localizationGO:00328802310.021
negative regulation of proteolysisGO:0045861740.021
regulation of purine nucleotide metabolic processGO:19005421690.021
regulation of secretion by cellGO:19035302490.020
cellular response to organonitrogen compoundGO:00714171450.020
regulation of cellular response to stressGO:00801351590.020
ribonucleoside catabolic processGO:00424542060.020
nucleotide catabolic processGO:00091662170.020
regulation of protein transportGO:00512231630.020
negative regulation of cell proliferationGO:00082852960.020
response to organic cyclic compoundGO:00140701980.020
epithelial cell proliferationGO:00506731740.020
positive regulation of cell activationGO:00508671580.020
regulation of kinase activityGO:00435492490.020
regulation of cell motilityGO:20001452360.020
dna metabolic processGO:00062593030.020
regulation of vesicle mediated transportGO:00606271390.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
t cell activationGO:00421102890.020
negative regulation of hydrolase activityGO:0051346710.020
alcohol metabolic processGO:00060661160.020
divalent inorganic cation homeostasisGO:00725071380.019
sensory organ morphogenesisGO:00905962420.019
purine ribonucleoside metabolic processGO:00461282410.019
positive regulation of t helper 1 cell differentiationGO:004562740.019
positive regulation of angiogenesisGO:0045766460.019
carboxylic acid biosynthetic processGO:0046394860.019
protein modification by small protein conjugation or removalGO:00706472070.019
regulation of proteolysisGO:00301621640.019
innate immune responseGO:00450871570.019
leukocyte migrationGO:00509001240.019
regulation of response to woundingGO:19030341890.019
calcium ion homeostasisGO:00550741270.019
posttranscriptional regulation of gene expressionGO:00106081550.019
male gamete generationGO:00482322850.019
regulation of protein maturationGO:1903317960.019
organonitrogen compound catabolic processGO:19015652640.019
sequestering of calcium ionGO:0051208180.019
cell matrix adhesionGO:0007160680.019
positive regulation of natural killer cell chemotaxisGO:200050310.018
regulation of protein processingGO:0070613960.018
cellular response to growth factor stimulusGO:00713631970.018
urogenital system developmentGO:00016552610.018
response to growth factorGO:00708481980.018
interleukin 12 secretionGO:007261030.018
protein localization to organelleGO:00333651850.018
muscle cell differentiationGO:00426922610.018
purine nucleoside metabolic processGO:00422782410.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
regulation of intracellular transportGO:00323861590.018
positive regulation of insulin receptor signaling pathwayGO:004662840.018
metal ion homeostasisGO:00550651890.018
negative regulation of protein maturationGO:1903318790.018
regulation of membrane potentialGO:00423911920.018
purine nucleoside catabolic processGO:00061522050.018
organic acid transportGO:00158491010.018
cholesterol metabolic processGO:0008203560.018
kidney developmentGO:00018222130.018
macromolecule glycosylationGO:0043413550.018
negative regulation of protein processingGO:0010955790.018
morphogenesis of a branching structureGO:00017632030.018
nucleoside triphosphate metabolic processGO:00091412300.017
leukocyte chemotaxisGO:0030595690.017
regulation of system processGO:00440572000.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.017
carboxylic acid transportGO:00469421000.017
cellular response to biotic stimulusGO:0071216920.017
blood circulationGO:00080151950.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
cellular response to lipidGO:00713961450.017
regulation of monocyte chemotaxisGO:009002530.017
nucleoside phosphate catabolic processGO:19012922220.017
regulation of chemotaxisGO:0050920530.017
intracellular protein transportGO:00068862040.017
organophosphate catabolic processGO:00464342320.017
cation transmembrane transportGO:00986552660.017
activation of immune responseGO:00022531380.017
rhythmic processGO:00485111740.017
negative regulation of intracellular signal transductionGO:19025321670.017
cytoplasmic transportGO:00164822340.017
purine nucleotide catabolic processGO:00061952110.017
regulation of eosinophil migrationGO:200041620.016
lymphocyte mediated immunityGO:00024491390.016
muscle system processGO:00030121410.016
positive regulation of mapk cascadeGO:00434101700.016
protein catabolic processGO:00301632210.016
negative regulation of cellular amine metabolic processGO:003323910.016
skeletal system developmentGO:00015013560.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
regulation of neuron differentiationGO:00456642810.016
extracellular structure organizationGO:00430621480.016
regulation of anatomical structure sizeGO:00900661780.016
neutrophil chemotaxisGO:0030593360.016
leukocyte proliferationGO:00706611720.016
cellular chemical homeostasisGO:00550822150.016
positive regulation of activation of membrane attack complexGO:000197020.016
camera type eye developmentGO:00430102660.016
t helper 1 cell cytokine productionGO:003574410.016
positive regulation of programmed cell deathGO:00430682180.016
negative regulation of macrophage apoptotic processGO:200011030.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
inflammatory responseGO:00069542440.015
positive regulation of kinase activityGO:00336741550.015
glycosyl compound catabolic processGO:19016582060.015
circulatory system processGO:00030131970.015
response to lipopolysaccharideGO:00324961280.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
negative regulation of cytokine productionGO:0001818840.015
protein activation cascadeGO:0072376190.015
skeletal muscle organ developmentGO:00605381630.015
organonitrogen compound biosynthetic processGO:19015661920.015
positive regulation of cellular component biogenesisGO:0044089940.015
defense response to bacteriumGO:00427421190.015
positive regulation of inflammatory responseGO:0050729470.015
inorganic cation transmembrane transportGO:00986622070.015
regulation of immunoglobulin production in mucosal tissueGO:200055710.015
inorganic ion transmembrane transportGO:00986602340.014
cellular response to cytokine stimulusGO:00713451890.014
immunoglobulin production in mucosal tissueGO:000242630.014
monocarboxylic acid metabolic processGO:00327871910.014
positive regulation of eosinophil migrationGO:200041820.014
cofactor metabolic processGO:0051186800.014
negative regulation of immune system processGO:00026832090.014
negative regulation of phosphorylationGO:00423261660.014
regulation of body fluid levelsGO:00508781620.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
protein secretionGO:00093061110.014
nuclear transportGO:00511691390.014
acylglycerol metabolic processGO:0006639550.014
regulation of cell substrate adhesionGO:0010810730.014
cdc42 protein signal transductionGO:003248800.014
carbohydrate derivative catabolic processGO:19011362310.014
regulation of lymphocyte mediated immunityGO:0002706840.014
single organism cell adhesionGO:00986021560.014
cell activation involved in immune responseGO:00022631260.014
regulation of protein serine threonine kinase activityGO:00719001570.014
regulation of cell projection organizationGO:00313442060.014
maintenance of locationGO:0051235890.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
cd4 positive alpha beta t cell cytokine productionGO:003574340.014
sterol metabolic processGO:0016125580.014
regulation of natural killer cell chemotaxisGO:200050110.014
protein targetingGO:00066051430.014
negative regulation of phosphorus metabolic processGO:00105631840.014
membrane organizationGO:00610242450.014
thymocyte migrationGO:007267920.014
positive regulation of t helper 2 cell cytokine productionGO:200055330.014
response to oxidative stressGO:00069791230.013
neutrophil migrationGO:1990266370.013
positive regulation of t helper 1 cell cytokine productionGO:200055610.013
calcium ion transportGO:00068161590.013
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.013
cellular macromolecule catabolic processGO:00442652060.013
nucleoside metabolic processGO:00091162460.013
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.013
positive regulation of immune effector processGO:00026991070.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
cell type specific apoptotic processGO:00972852680.013
regulation of multi organism processGO:00439001110.013
positive regulation of protein kinase activityGO:00458601440.013
striated muscle cell developmentGO:00550021250.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
protein modification by small protein conjugationGO:00324461870.013
cellular response to lipopolysaccharideGO:0071222770.013
production of molecular mediator of immune responseGO:00024401030.013
regulation of leukocyte proliferationGO:00706631210.013
cellular protein catabolic processGO:00442571550.013
amino acid transportGO:0006865610.013
endocytosisGO:00068971680.013
Fly
regulation of homeostatic processGO:00328441820.013
positive regulation of apoptotic processGO:00430652170.013
protein ubiquitinationGO:00165671710.013
regulation of apoptotic signaling pathwayGO:20012331970.013
regulation of protein kinase activityGO:00458592320.013
regulation of fat cell differentiationGO:0045598810.013
cellular calcium ion homeostasisGO:00068741190.013
leukocyte activation involved in immune responseGO:00023661260.013
gtp metabolic processGO:00460391440.013
regulation of cell cycleGO:00517262810.013
organelle localizationGO:00516401790.013
regulation of t cell proliferationGO:0042129920.013
positive regulation of defense responseGO:00313491240.013
myeloid cell homeostasisGO:00022621140.012
skin developmentGO:00435882200.012
cellular carbohydrate metabolic processGO:00442621190.012
skeletal system morphogenesisGO:00487052030.012
response to oxygen levelsGO:0070482620.012
macromolecule catabolic processGO:00090572810.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
guanosine containing compound catabolic processGO:19010691440.012
positive regulation of cell developmentGO:00107202370.012
regulation of epithelial cell proliferationGO:00506781410.012
coagulationGO:0050817780.012
positive regulation of cell substrate adhesionGO:0010811470.012
glycosylationGO:0070085620.012
gland developmentGO:00487323300.012
branching morphogenesis of an epithelial tubeGO:00487541590.012
renal system developmentGO:00720012250.012
developmental growth involved in morphogenesisGO:00605601380.012
connective tissue developmentGO:00614481790.012
regulation of purine nucleotide catabolic processGO:00331211220.012
glycerolipid metabolic processGO:00464861220.012
reactive nitrogen species metabolic processGO:200105700.012
positive regulation of reactive oxygen species metabolic processGO:2000379110.012
peptide secretionGO:00027901140.012
response to radiationGO:00093141650.012
cellular response to hormone stimulusGO:00328701500.012
positive regulation of protein transportGO:0051222930.012
positive regulation of cell adhesionGO:0045785800.012
positive regulation of chemotaxisGO:0050921380.012
activation of nf kappab inducing kinase activityGO:000725040.012
amide transportGO:00428861380.012
nucleocytoplasmic transportGO:00069131390.012
positive regulation of hydrolase activityGO:00513451480.012
positive regulation of nucleotide metabolic processGO:00459811140.012
positive regulation of lymphocyte mediated immunityGO:0002708620.012
regulation of muscle tissue developmentGO:1901861970.012
response to transforming growth factor betaGO:0071559880.012
regulation of nucleoside metabolic processGO:00091181300.012
regulation of ion transportGO:00432692150.012
cytokine secretionGO:0050663720.012
regulation of lipid biosynthetic processGO:0046890540.012
fatty acid biosynthetic processGO:0006633410.012
fat soluble vitamin biosynthetic processGO:004236240.012
adaptive immune responseGO:00022501550.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
rna interferenceGO:001624620.012
cytosolic calcium ion homeostasisGO:0051480700.012
positive regulation of tumor necrosis factor productionGO:0032760300.012
sulfur compound metabolic processGO:00067901000.011
regulation of lipid metabolic processGO:00192161180.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
monosaccharide metabolic processGO:00059961060.011
muscle cell developmentGO:00550011330.011
g protein coupled receptor signaling pathwayGO:00071862430.011
single organismal cell cell adhesionGO:00163371310.011
organophosphate biosynthetic processGO:00904071220.011
regulation of cd4 positive alpha beta t cell proliferationGO:200056120.011
neuron deathGO:00709971540.011
mesonephros developmentGO:0001823970.011
positive regulation of cell motilityGO:20001471160.011
cytokine production involved in immune responseGO:0002367340.011
cellular response to peptide hormone stimulusGO:0071375920.011
regulation of protein catabolic processGO:00421761080.011
lipid localizationGO:00108761260.011
epithelial cell developmentGO:00020641590.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
protein importGO:00170381010.011
detection of molecule of bacterial originGO:003249020.011
actin cytoskeleton organizationGO:00300362200.011
negative regulation of peptidase activityGO:0010466460.011
development of primary female sexual characteristicsGO:0046545730.011
regulation of interleukin 8 productionGO:003267730.011
regulation of nucleotide catabolic processGO:00308111220.011
myeloid leukocyte mediated immunityGO:0002444420.011
l amino acid transportGO:0015807320.011
cellular response to molecule of bacterial originGO:0071219830.011
regulation of lymphocyte activationGO:00512492400.011
sensory perceptionGO:00076002450.011
granulocyte chemotaxisGO:0071621390.011
cellular response to dna damage stimulusGO:00069742070.011
blood coagulationGO:0007596760.011
embryonic organ morphogenesisGO:00485622760.011
response to inorganic substanceGO:0010035960.011
peptide transportGO:00158331330.011
small molecule catabolic processGO:0044282710.011
developmental maturationGO:00217001930.011
protein glycosylationGO:0006486550.011
natural killer cell chemotaxisGO:003574710.011
hexose metabolic processGO:0019318980.011
ameboidal type cell migrationGO:00016671280.011
carbohydrate biosynthetic processGO:0016051740.011
guanosine containing compound metabolic processGO:19010681440.011
positive regulation of proteolysisGO:0045862850.011
organic hydroxy compound transportGO:0015850930.011
regulation of peptidase activityGO:0052547960.011
positive regulation of apoptotic cell clearanceGO:200042730.011
regulation of neutrophil mediated killing of bacteriumGO:007095010.011
negative regulation of cellular component organizationGO:00511291940.011
interleukin 8 productionGO:003263740.011
multicellular organismal homeostasisGO:00488711640.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
regulation of neuron deathGO:19012141340.011
negative regulation of lipoprotein lipase activityGO:005100510.010
response to insulinGO:00328681000.010
peptidyl amino acid modificationGO:00181933360.010
reactive oxygen species biosynthetic processGO:190340980.010
cell recognitionGO:0008037830.010
muscle contractionGO:00069361010.010
response to extracellular stimulusGO:00099911270.010
anatomical structure homeostasisGO:00602491450.010
eosinophil migrationGO:007267730.010
multi multicellular organism processGO:00447061090.010
positive regulation of cell migrationGO:00303351090.010
regulation of cell cycle processGO:00105641600.010
hormone secretionGO:00468791280.010
myotube differentiationGO:00149021050.010
positive regulation of cytosolic calcium ion concentrationGO:0007204650.010
mitotic cell cycle processGO:19030471590.010
heart morphogenesisGO:00030071780.010
granulocyte migrationGO:0097530430.010
regulation of b cell chemotaxisGO:200053720.010
exocytosisGO:00068871210.010
monocarboxylic acid biosynthetic processGO:0072330610.010
nuclear importGO:0051170950.010
ear developmentGO:00435832000.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
nuclear divisionGO:00002801580.010
gonad developmentGO:00084061410.010

Pla1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.035
disease of anatomical entityDOID:700.031
nervous system diseaseDOID:86300.031
immune system diseaseDOID:291400.016
hematopoietic system diseaseDOID:7400.015
inherited metabolic disorderDOID:65500.013
sensory system diseaseDOID:005015500.013
central nervous system diseaseDOID:33100.012
musculoskeletal system diseaseDOID:1700.011