Mus musculus

0 known processes

Kpna1

karyopherin (importin) alpha 1

(Aliases: NPI1,IPOA5,mSRP1,Rch2,AW494490)

Kpna1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein catabolic processGO:00442571550.856
protein modification by small protein conjugation or removalGO:00706472070.658
proteolysis involved in cellular protein catabolic processGO:00516031470.645
proteasomal protein catabolic processGO:0010498980.530
endoplasmic reticulum tubular network organizationGO:007178610.519
macromolecule catabolic processGO:00090572810.505
cellular macromolecule catabolic processGO:00442652060.435
protein catabolic processGO:00301632210.433
organelle localizationGO:00516401790.427
modification dependent macromolecule catabolic processGO:00436321330.426
protein ubiquitinationGO:00165671710.407
multicellular organismal macromolecule catabolic processGO:004426610.389
modification dependent protein catabolic processGO:00199411330.376
positive regulation of nfat protein import into nucleusGO:005153310.284
response to reactive oxygen speciesGO:0000302560.277
response to oxidative stressGO:00069791230.276
protein importGO:00170381010.273
Mouse Rat
protein modification by small protein removalGO:0070646210.253
regulation of mitochondrial fissionGO:009014030.248
protein modification by small protein conjugationGO:00324461870.246
regulation of intracellular transportGO:00323861590.238
Rat
regulation of protein targetingGO:1903533610.209
Rat
ubiquitin dependent protein catabolic processGO:00065111290.206
positive regulation of intracellular transportGO:0032388700.181
Rat
ras protein signal transductionGO:0007265770.171
multicellular organismal protein metabolic processGO:004426820.158
organelle disassemblyGO:190300820.147
positive regulation of protein transportGO:0051222930.146
Rat
regulation of protein transportGO:00512231630.146
Rat
nuclear transportGO:00511691390.146
Mouse Rat
regulation of nucleocytoplasmic transportGO:0046822730.143
Rat
regulation of cellular response to stressGO:00801351590.135
cellular response to arsenic containing substanceGO:007124340.131
nucleocytoplasmic transportGO:00069131390.128
Mouse Rat
multicellular organismal protein catabolic processGO:004425410.123
mitotic cell cycleGO:00002781950.115
cytoplasmic transportGO:00164822340.113
Mouse Rat
intracellular protein transportGO:00068862040.111
Mouse Rat
posttranscriptional regulation of gene expressionGO:00106081550.110
protein digestionGO:004425610.109
regulation of proteolysisGO:00301621640.108
protein localization to cell leading edgeGO:190246310.108
cellular homeostasisGO:00197252400.107
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.107
regulation of apoptotic signaling pathwayGO:20012331970.097
cellular amino acid metabolic processGO:00065201030.091
ribonucleoprotein complex disassemblyGO:003298830.091
positive regulation of cytoplasmic transportGO:1903651400.091
Rat
negative regulation of protein metabolic processGO:00512482820.091
regulation of cell cycleGO:00517262810.089
regulation of protein localizationGO:00328802310.089
Rat
regulation of cell cycle processGO:00105641600.083
regulation of protein catabolic processGO:00421761080.079
lateral inhibitionGO:004633110.078
regulation of mapk cascadeGO:00434082480.077
protein import into nucleusGO:0006606950.077
Mouse Rat
rna interferenceGO:001624620.077
muscle cell developmentGO:00550011330.077
negative regulation of intracellular signal transductionGO:19025321670.077
regulation of establishment of protein localizationGO:00702011810.075
Rat
cellular amine metabolic processGO:0044106440.075
transforming growth factor beta receptor signaling pathwayGO:0007179710.075
dendrite developmentGO:00163581150.074
regulation of transcription factor import into nucleusGO:0042990240.074
regulation of defense responseGO:00313472330.074
regulation of polyamine transmembrane transportGO:190226750.074
positive regulation of protein localization to nucleusGO:1900182300.073
Rat
membrane fusionGO:0061025380.071
dna endoreduplicationGO:004202340.071
muscle cell differentiationGO:00426922610.070
protein desumoylationGO:001692620.069
regulation of cytoplasmic transportGO:19036491120.069
Rat
protein localization to nucleusGO:00345041210.067
Mouse Rat
response to growth factorGO:00708481980.066
mapk cascadeGO:00001652810.066
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.065
cajal body organizationGO:003057610.065
n terminal protein amino acid modificationGO:003136560.064
response to uvGO:0009411440.063
protein localization to organelleGO:00333651850.062
Mouse Rat
regulation of cellular catabolic processGO:00313292420.060
cellular component assembly involved in morphogenesisGO:00109271390.060
negative regulation of protein modification processGO:00314001630.059
bmp signaling pathwayGO:0030509930.059
negative regulation of cellular protein metabolic processGO:00322692470.058
positive regulation of protein import into nucleusGO:0042307260.058
Rat
amine metabolic processGO:0009308450.056
gene silencingGO:0016458380.056
mitochondrion distributionGO:004831140.055
regulation of protein kinase activityGO:00458592320.055
protein polyubiquitinationGO:0000209330.054
establishment of organelle localizationGO:00516561220.053
organelle fissionGO:00482851700.053
membrane organizationGO:00610242450.052
single organism nuclear importGO:1902593950.052
Mouse Rat
positive regulation of intracellular protein transportGO:0090316420.051
Rat
chromatin organizationGO:00063252060.051
positive regulation of nucleocytoplasmic transportGO:0046824300.050
Rat
cell junction maintenanceGO:003433140.049
negative regulation of proteolysisGO:0045861740.049
p38mapk cascadeGO:003806640.047
establishment of protein localization to organelleGO:00725941180.047
Mouse Rat
chromatin modificationGO:00165681870.047
blastocyst developmentGO:0001824800.046
response to transforming growth factor betaGO:0071559880.046
regulation of neuron apoptotic processGO:00435231220.044
nucleoside metabolic processGO:00091162460.044
polyamine biosynthetic processGO:000659620.044
misfolded protein transportGO:007084310.044
cation transportGO:00068123990.043
striated muscle tissue developmentGO:00147062930.043
regulation of protein localization to nucleusGO:1900180600.043
Rat
regulation of transferase activityGO:00513382630.043
negative regulation of mitotic cell cycleGO:0045930580.042
engulfment of apoptotic cellGO:004365230.041
regulation of cell projection organizationGO:00313442060.041
mitochondrion organizationGO:00070051340.040
regulation of cellular protein catabolic processGO:1903362610.040
alpha amino acid metabolic processGO:1901605590.039
striated muscle cell developmentGO:00550021250.039
compound eye developmentGO:004874910.039
de novo protein foldingGO:000645890.039
positive regulation of mitotic metaphase anaphase transitionGO:004584220.039
mitochondrion transport along microtubuleGO:004749730.039
negative regulation of protein phosphorylationGO:00019331260.038
protein oligomerizationGO:0051259670.037
regulation of cell cycle phase transitionGO:1901987770.037
regulation of map kinase activityGO:00434051200.036
rho protein signal transductionGO:0007266320.036
negative regulation of protein serine threonine kinase activityGO:0071901490.036
negative regulation of molecular functionGO:00440922580.036
organic cyclic compound catabolic processGO:19013612950.036
nuclear importGO:0051170950.036
Mouse Rat
digestive tract developmentGO:00485651900.035
negative regulation of defense responseGO:0031348770.035
nitrogen compound transportGO:00717052710.035
regulation of nfat protein import into nucleusGO:005153240.035
translationGO:0006412930.034
synapsisGO:0007129340.034
trophoblast giant cell differentiationGO:0060707150.034
muscle tissue developmentGO:00605373080.034
regulation of intracellular protein transportGO:0033157820.034
Rat
regulation of ras protein signal transductionGO:00465781140.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
trophectodermal cellular morphogenesisGO:000183130.033
cellular response to dna damage stimulusGO:00069742070.033
nfat protein import into nucleusGO:005153160.033
myosin filament assemblyGO:003103420.033
regulation of anatomical structure sizeGO:00900661780.032
macromolecular complex disassemblyGO:0032984430.032
dna metabolic processGO:00062593030.032
chromosome segregationGO:0007059480.031
cellular response to inorganic substanceGO:0071241370.031
transcription factor import into nucleusGO:0042991260.031
protein targetingGO:00066051430.031
Mouse Rat
mitotic cell cycle processGO:19030471590.030
mitotic cytokinesisGO:000028140.030
cellular modified amino acid metabolic processGO:0006575630.030
stress activated mapk cascadeGO:0051403800.030
action potentialGO:0001508780.029
regulation of neuron differentiationGO:00456642810.029
meiosis iGO:0007127600.029
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.029
homeostasis of number of cellsGO:00488722100.029
ribonucleoprotein complex subunit organizationGO:0071826280.028
negative regulation of phosphate metabolic processGO:00459361840.028
actin cytoskeleton organizationGO:00300362200.028
dna replicationGO:0006260520.028
cell growthGO:00160491300.028
multicellular organismal homeostasisGO:00488711640.028
cellular response to oxidative stressGO:0034599760.028
histone modificationGO:00165701590.027
nuclear divisionGO:00002801580.027
sister chromatid segregationGO:0000819200.027
small gtpase mediated signal transductionGO:0007264970.027
endoplasmic reticulum organizationGO:0007029100.027
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.027
negative regulation of protein maturationGO:1903318790.027
amide transportGO:00428861380.027
synaptic transmissionGO:00072683290.027
copii coated vesicle buddingGO:009011420.027
physiological muscle hypertrophyGO:000329830.026
intrinsic apoptotic signaling pathwayGO:00971931320.026
mitotic cell cycle checkpointGO:0007093310.026
regionalizationGO:00030023370.025
regulation of neuron deathGO:19012141340.025
regulation of mitotic cell cycle phase transitionGO:1901990730.025
cellular protein complex disassemblyGO:0043624360.025
localization within membraneGO:005166840.025
microtubule based processGO:00070172360.025
negative regulation of phosphorylationGO:00423261660.025
regulation of organelle organizationGO:00330432890.025
striated muscle myosin thick filament assemblyGO:007168810.025
embryonic placenta developmentGO:0001892980.025
macroautophagyGO:0016236210.025
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.025
gene silencing by rnaGO:0031047190.024
neuron deathGO:00709971540.024
mitochondrial membrane organizationGO:0007006260.024
response to inorganic substanceGO:0010035960.024
cell growth involved in cardiac muscle cell developmentGO:006104930.024
stress activated protein kinase signaling cascadeGO:0031098810.024
response to hydrogen peroxideGO:0042542320.023
heterocycle catabolic processGO:00467002800.023
regulation of jnk cascadeGO:0046328620.023
negative regulation of protein ubiquitinationGO:0031397190.023
rhythmic processGO:00485111740.023
signal transduction by p53 class mediatorGO:0072331510.023
protein complex disassemblyGO:0043241400.023
regulation of mitotic cell cycleGO:00073461260.023
heart growthGO:0060419450.023
negative regulation of kinase activityGO:0033673810.023
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathwayGO:1902235110.023
physiological cardiac muscle hypertrophyGO:000330130.022
organonitrogen compound catabolic processGO:19015652640.022
protein refoldingGO:004202610.022
cellular ketone metabolic processGO:0042180840.022
inflammatory responseGO:00069542440.021
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.021
vesicle organizationGO:0016050600.021
negative regulation of neuron deathGO:1901215980.021
endocytosisGO:00068971680.021
regulation of cellular component biogenesisGO:00440871810.021
cell cycle switching mitotic to meiotic cell cycleGO:005172810.021
regulation of cell migrationGO:00303342190.021
multicellular organismal agingGO:0010259240.021
multi multicellular organism processGO:00447061090.021
Mouse
cardiac muscle tissue developmentGO:00487381300.021
purine ribonucleotide catabolic processGO:00091542080.021
jnk cascadeGO:0007254720.021
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.020
regulation of translationGO:0006417710.020
vesicle localizationGO:0051648860.020
blastocyst formationGO:0001825330.020
regulation of wnt signaling pathwayGO:00301111230.020
mesoderm morphogenesisGO:0048332640.020
actomyosin structure organizationGO:0031032560.020
negative regulation of phosphorus metabolic processGO:00105631840.020
neuron apoptotic processGO:00514021420.019
cell cycle g1 s phase transitionGO:0044843570.019
establishment of vesicle localizationGO:0051650810.019
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.019
nucleus organizationGO:0006997450.019
negative regulation of map kinase activityGO:0043407340.019
negative regulation of ras protein signal transductionGO:0046580180.019
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.019
myosin filament organizationGO:003103330.019
digestive tract morphogenesisGO:00485461470.019
digestive system developmentGO:00551232000.019
peptide transportGO:00158331330.019
regulation of cellular ketone metabolic processGO:0010565660.019
positive regulation of programmed cell deathGO:00430682180.019
regulation of kinase activityGO:00435492490.019
peptidyl threonine modificationGO:0018210310.019
centrosome separationGO:005129940.019
intracellular steroid hormone receptor signaling pathwayGO:0030518290.019
axonogenesisGO:00074092740.019
posttranscriptional gene silencingGO:0016441100.018
response to radiationGO:00093141650.018
amine biosynthetic processGO:000930930.018
translational initiationGO:0006413240.018
stem cell differentiationGO:00488632680.018
regulation of cellular amino acid metabolic processGO:000652150.018
spermine metabolic processGO:000821530.018
regulation of response to woundingGO:19030341890.018
response to peptideGO:19016521360.018
regulation of transpositionGO:001052820.018
digestionGO:0007586400.018
formation of primary germ layerGO:0001704770.018
protein targeting to erGO:004504720.018
organ growthGO:00352651170.018
regulation of peptide transportGO:0090087910.018
cardiac muscle cell differentiationGO:0055007690.018
regulation of stem cell differentiationGO:2000736500.018
negative regulation of cell cycleGO:00457861230.018
gastrulationGO:00073691160.018
cellular response to growth factor stimulusGO:00713631970.018
meiotic cell cycle processGO:1903046770.018
transmission of nerve impulseGO:0019226760.018
regulation of protein serine threonine kinase activityGO:00719001570.018
phosphatidylethanolamine metabolic processGO:004633720.018
positive regulation of mitotic sister chromatid separationGO:190197020.018
tube closureGO:0060606910.017
cellular response to amino acid stimulusGO:0071230290.017
cardiocyte differentiationGO:0035051870.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
morphogenesis of embryonic epitheliumGO:00163311590.017
protein prenylationGO:001834230.017
negative regulation of cell proliferationGO:00082852960.017
guanosine containing compound metabolic processGO:19010681440.017
endomembrane system organizationGO:00102561470.017
nucleoside phosphate catabolic processGO:19012922220.017
cell cycle checkpointGO:0000075470.017
circulatory system processGO:00030131970.017
cellular response to cadmium ionGO:007127630.016
skeletal muscle organ developmentGO:00605381630.016
establishment of protein localization to endoplasmic reticulumGO:007259920.016
positive regulation of cell deathGO:00109422240.016
response to organonitrogen compoundGO:00102432460.016
positive regulation of cellular amine metabolic processGO:003324050.016
protein methylationGO:0006479810.016
negative regulation of toll signaling pathwayGO:004575110.016
negative regulation of response to woundingGO:1903035770.016
maintenance of locationGO:0051235890.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
regulation of ion transportGO:00432692150.016
negative regulation of cellular component organizationGO:00511291940.016
cell agingGO:0007569350.016
positive regulation of mapk cascadeGO:00434101700.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
response to light stimulusGO:00094161350.016
protein deubiquitinationGO:0016579190.016
protein dna complex subunit organizationGO:0071824280.016
multicellular organismal signalingGO:0035637910.016
regulation of homeostatic processGO:00328441820.015
negative regulation of cellular protein catabolic processGO:1903363220.015
male gamete generationGO:00482322850.015
positive regulation of cellular catabolic processGO:00313311480.015
dendritic spine developmentGO:0060996300.015
posttranscriptional gene silencing by rnaGO:0035194100.015
single organism cell adhesionGO:00986021560.015
neuronal action potentialGO:0019228540.015
positive regulation of protein phosphorylationGO:00019342420.015
trna wobble base modificationGO:000209720.014
regulation of proteasomal protein catabolic processGO:0061136460.014
positive regulation of chromosome segregationGO:005198440.014
gtp metabolic processGO:00460391440.014
protein secretionGO:00093061110.014
positive regulation of protein modification processGO:00314012990.014
response to amino acidGO:0043200370.014
chromosome organization involved in meiosisGO:0070192390.014
positive regulation of transcription factor import into nucleusGO:004299380.014
dephosphorylationGO:00163111290.014
negative regulation of mitotic cell cycle phase transitionGO:1901991450.014
regulation of membrane potentialGO:00423911920.014
apoptotic signaling pathwayGO:00971903060.014
protein maturationGO:00516041760.014
g1 s transition of mitotic cell cycleGO:0000082570.014
transcription from rna polymerase i promoterGO:0006360130.014
cellular ion homeostasisGO:00068731650.014
trophectodermal cell differentiationGO:0001829210.014
chiasma assemblyGO:005102660.014
protein foldingGO:0006457280.014
regulation of protein oligomerizationGO:003245940.014
metaphase plate congressionGO:005131020.013
regulation of histone modificationGO:0031056560.013
cellular senescenceGO:0090398110.013
regulation of stress activated mapk cascadeGO:0032872690.013
myotube differentiationGO:00149021050.013
response to extracellular stimulusGO:00099911270.013
aromatic compound catabolic processGO:00194392860.013
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.013
protein k63 linked ubiquitinationGO:007053460.013
monoubiquitinated protein deubiquitinationGO:003552020.013
covalent chromatin modificationGO:00165691630.013
calcium mediated signaling using intracellular calcium sourceGO:003558430.013
regulation of inflammatory responseGO:00507271470.013
regulation of rho protein signal transductionGO:0035023710.013
primary neural tube formationGO:0014020950.013
connective tissue developmentGO:00614481790.013
positive regulation of lipid storageGO:0010884100.013
mesodermal cell migrationGO:000807840.013
monocarboxylic acid metabolic processGO:00327871910.013
regulation of angiogenesisGO:0045765810.012
post golgi vesicle mediated transportGO:0006892130.012
n terminal protein lipidationGO:000649850.012
regulation of protein ubiquitinationGO:0031396520.012
epithelial tube morphogenesisGO:00605623030.012
cellular response to molecule of bacterial originGO:0071219830.012
t cell activationGO:00421102890.012
corpus callosum morphogenesisGO:002154030.012
nuclear dna replicationGO:003326030.012
organelle assemblyGO:00709251770.012
divalent metal ion transportGO:00708381720.012
exocytosisGO:00068871210.012
gtp catabolic processGO:00061841430.012
response to acid chemicalGO:00011011110.012
regulation of definitive erythrocyte differentiationGO:001072430.012
positive regulation of cell cycleGO:0045787920.012
positive regulation of stress activated mapk cascadeGO:0032874480.012
lymphocyte proliferationGO:00466511640.012
calcium ion homeostasisGO:00550741270.012
histone h2a ubiquitinationGO:003352230.012
negative regulation of nervous system developmentGO:00519611560.012
dna integrity checkpointGO:0031570280.012
synapse organizationGO:00508081250.011
positive regulation of cell motilityGO:20001471160.011
regulation of protein import into nucleusGO:0042306520.011
Rat
response to alcoholGO:0097305480.011
germ cell developmentGO:00072811850.011
apoptotic mitochondrial changesGO:0008637480.011
organonitrogen compound biosynthetic processGO:19015661920.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
vascular process in circulatory systemGO:0003018620.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
skeletal muscle myosin thick filament assemblyGO:003024110.011
oocyte axis specificationGO:000730920.011
mitochondrion localizationGO:005164690.011
negative regulation of cellular catabolic processGO:0031330470.011
labyrinthine layer developmentGO:0060711490.011
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.011
positive regulation of kinase activityGO:00336741550.011
cellular nitrogen compound catabolic processGO:00442702800.011
tissue remodelingGO:00487711020.011
protein lipidationGO:0006497280.011
adult behaviorGO:00305341350.011
pallium developmentGO:00215431200.011
protein processingGO:00164851630.011
cyclin catabolic processGO:000805410.011
cellular response to peptide hormone stimulusGO:0071375920.011
maintenance of location in cellGO:0051651240.011
learning or memoryGO:00076111480.011
cellular response to external stimulusGO:0071496880.011
central nervous system projection neuron axonogenesisGO:0021952210.011
regulation of protein processingGO:0070613960.011
spermatogenesisGO:00072832840.011
response to oxygen levelsGO:0070482620.011
negative regulation of transpositionGO:001052920.011
response to epidermal growth factorGO:007084940.011
er associated ubiquitin dependent protein catabolic processGO:0030433100.011
neural tube developmentGO:00219151600.011
regulation of chromosome organizationGO:0033044830.011
nucleoside triphosphate catabolic processGO:00091432050.011
protein autophosphorylationGO:0046777610.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
negative regulation of immune system processGO:00026832090.010
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.010
cell cycle switchingGO:006018410.010
intracellular receptor signaling pathwayGO:0030522740.010
anatomical structure homeostasisGO:00602491450.010
phosphorylated carbohydrate dephosphorylationGO:004683840.010
ribonucleotide metabolic processGO:00092592910.010
nucleus localizationGO:0051647200.010
cellular protein complex assemblyGO:00436231160.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
glucose homeostasisGO:00425931280.010
myeloid cell differentiationGO:00300992330.010
positive regulation of protein kinase activityGO:00458601440.010
negative regulation of cell cycle processGO:0010948690.010
epithelium migrationGO:0090132630.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
cardiac muscle tissue growthGO:0055017370.010
cation homeostasisGO:00550802120.010
ossificationGO:00015032160.010
response to xenobiotic stimulusGO:0009410130.010
nucleobase containing small molecule metabolic processGO:00550863520.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
female meiosis chromosome segregationGO:001632110.010
placenta developmentGO:00018901400.010
oogenesisGO:0048477560.010
regulation of toll signaling pathwayGO:000859210.010
cellular response to starvationGO:0009267570.010

Kpna1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
eye and adnexa diseaseDOID:149200.020
sensory system diseaseDOID:005015500.020
disease of anatomical entityDOID:700.020