Mus musculus

0 known processes

Ttk

Ttk protein kinase

(Aliases: Esk1,esk,PYT,AL022661)

Ttk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.870
nuclear divisionGO:00002801580.846
Yeast Zebrafish Fly
meiotic cell cycle processGO:1903046770.835
Zebrafish Fly
microtubule cytoskeleton organizationGO:00002261570.726
Yeast
regulation of cell cycleGO:00517262810.715
Yeast Zebrafish Fly
mitotic cell cycle processGO:19030471590.711
Yeast Zebrafish Fly
mitotic cell cycleGO:00002781950.683
Yeast Zebrafish Fly
organelle fissionGO:00482851700.600
Yeast Zebrafish Fly
regulation of cell cycle processGO:00105641600.545
Yeast Zebrafish Fly
astral microtubule organizationGO:003095330.537
microtubule based processGO:00070172360.535
Yeast
organelle assemblyGO:00709251770.505
Yeast
cell cycle checkpointGO:0000075470.460
Yeast Zebrafish Fly
centrosome cycleGO:0007098230.457
spindle assembly involved in mitosisGO:009030740.454
cellular response to dna damage stimulusGO:00069742070.438
double strand break repairGO:0006302480.411
dna repairGO:00062811070.393
microtubule organizing center organizationGO:0031023280.378
Yeast
regulation of microtubule based processGO:0032886520.365
Yeast
mitotic nuclear divisionGO:0007067480.360
Yeast Fly
negative regulation of cell cycleGO:00457861230.331
Yeast Zebrafish Fly
regulation of cell divisionGO:0051302760.317
Yeast Fly
regulation of mitotic cell cycleGO:00073461260.314
Yeast Zebrafish Fly
cell divisionGO:00513011200.309
Yeast Fly
negative regulation of cell cycle phase transitionGO:1901988480.294
Yeast Zebrafish Fly
mitotic sister chromatid segregationGO:0000070140.293
Yeast Fly
regulation of mitotic cell cycle phase transitionGO:1901990730.292
Yeast Zebrafish Fly
meiotic nuclear divisionGO:00071261150.284
Zebrafish Fly
establishment of organelle localizationGO:00516561220.283
Yeast Fly
purine containing compound metabolic processGO:00725213110.266
protein catabolic processGO:00301632210.262
Yeast Fly
mitotic chromosome condensationGO:000707610.261
establishment of meiotic spindle orientationGO:005129610.246
chromosome segregationGO:0007059480.242
Yeast Zebrafish Fly
female meiosis chromosome segregationGO:001632110.225
Zebrafish Fly
regulation of organelle organizationGO:00330432890.224
Yeast Fly
male meiosisGO:0007140370.222
Zebrafish
translesion synthesisGO:001998510.218
microtubule based movementGO:0007018840.215
regulation of mitosisGO:0007088290.215
Yeast Fly
dna recombinationGO:0006310920.210
meiosis iGO:0007127600.205
Fly
gonad developmentGO:00084061410.202
cytokinesisGO:0000910170.191
mitotic cytokinesisGO:000028140.182
positive regulation of cell cycleGO:0045787920.181
meiotic cell cycleGO:00513211220.177
Zebrafish Fly
spindle assembly involved in female meiosisGO:000705630.177
nucleoside triphosphate metabolic processGO:00091412300.176
mitotic sister chromatid cohesionGO:000706410.170
cellular macromolecule catabolic processGO:00442652060.153
Yeast Fly
dna biosynthetic processGO:0071897220.148
negative regulation of cellular component organizationGO:00511291940.148
Yeast Fly
centrosome duplicationGO:0051298160.143
regulation of protein localizationGO:00328802310.143
Yeast
ribonucleoside catabolic processGO:00424542060.135
metaphase plate congressionGO:005131020.130
Yeast Fly
nucleoside phosphate catabolic processGO:19012922220.129
purine nucleotide metabolic processGO:00061633020.125
histone threonine phosphorylationGO:003540510.124
female meiotic divisionGO:0007143210.124
Zebrafish Fly
chromatin organizationGO:00063252060.122
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.120
Yeast Fly
organic cyclic compound catabolic processGO:19013612950.116
spindle assembly involved in meiosisGO:009030640.112
centrosome organizationGO:0051297260.111
positive regulation of mitotic cell cycleGO:0045931410.111
negative regulation of mitotic cell cycleGO:0045930580.110
Yeast Zebrafish Fly
centrosome separationGO:005129940.109
maintenance of locationGO:0051235890.108
Yeast
chromatin modificationGO:00165681870.105
microtubule cytoskeleton organization involved in mitosisGO:190285040.105
Yeast
synapsisGO:0007129340.097
organelle localizationGO:00516401790.094
Yeast Fly
protein depolymerizationGO:0051261340.090
male gamete generationGO:00482322850.086
regulation of transferase activityGO:00513382630.080
modification dependent macromolecule catabolic processGO:00436321330.080
Yeast Fly
positive regulation of cellular catabolic processGO:00313311480.079
regulation of microtubule cytoskeleton organizationGO:0070507370.077
Yeast
meiotic cytokinesisGO:003320650.075
glycosyl compound catabolic processGO:19016582060.074
negative regulation of microtubule polymerization or depolymerizationGO:0031111150.074
macromolecule catabolic processGO:00090572810.073
Yeast Fly
response to radiationGO:00093141650.069
microtubule polymerization or depolymerizationGO:0031109260.067
chromosome separationGO:0051304140.066
Yeast Fly
nucleoside triphosphate catabolic processGO:00091432050.066
ribonucleoside monophosphate catabolic processGO:0009158570.065
spindle checkpointGO:0031577120.065
Yeast Fly
ribonucleoside metabolic processGO:00091192450.063
meiotic chromosome segregationGO:0045132190.062
Zebrafish Fly
nucleoside phosphate metabolic processGO:00067533380.062
regulation of cellular response to stressGO:00801351590.060
cellular amino acid metabolic processGO:00065201030.059
apoptotic signaling pathwayGO:00971903060.059
spindle assemblyGO:0051225130.059
Yeast
ribonucleoside triphosphate metabolic processGO:00091992200.059
purine nucleoside triphosphate catabolic processGO:00091462030.059
cytokinetic processGO:003250620.057
regulation of chromosome organizationGO:0033044830.057
Yeast Fly
recombinational repairGO:0000725210.057
purine nucleotide catabolic processGO:00061952110.057
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.056
Yeast
organonitrogen compound catabolic processGO:19015652640.056
glycosyl compound metabolic processGO:19016572460.056
purine ribonucleoside catabolic processGO:00461302050.054
development of primary sexual characteristicsGO:00451371430.054
regulation of cell cycle phase transitionGO:1901987770.053
Yeast Zebrafish Fly
heterocycle catabolic processGO:00467002800.053
spermatogenesisGO:00072832840.053
ribose phosphate metabolic processGO:00196932910.053
nucleotide catabolic processGO:00091662170.053
cellular amine metabolic processGO:0044106440.053
regulation of proteasomal protein catabolic processGO:0061136460.052
Yeast Fly
ribonucleotide metabolic processGO:00092592910.052
nucleotide metabolic processGO:00091173320.052
mitotic centrosome separationGO:000710040.052
positive regulation of apoptotic processGO:00430652170.051
dna packagingGO:0006323300.051
nucleobase containing small molecule metabolic processGO:00550863520.051
attachment of spindle microtubules to kinetochoreGO:000860840.051
Yeast
regulation of double strand break repair via homologous recombinationGO:001056920.050
organophosphate catabolic processGO:00464342320.050
ubiquitin dependent protein catabolic processGO:00065111290.050
Yeast Fly
nucleoside metabolic processGO:00091162460.050
positive regulation of cellular amine metabolic processGO:003324050.049
purine ribonucleotide metabolic processGO:00091502900.049
purine nucleoside triphosphate metabolic processGO:00091442260.049
purine nucleoside metabolic processGO:00422782410.049
carbohydrate derivative catabolic processGO:19011362310.049
sister chromatid segregationGO:0000819200.048
Yeast Fly
purine ribonucleotide catabolic processGO:00091542080.048
purine nucleoside monophosphate metabolic processGO:0009126810.048
cellular nitrogen compound catabolic processGO:00442702800.048
purine nucleoside catabolic processGO:00061522050.047
reciprocal meiotic recombinationGO:0007131160.047
cellular response to abiotic stimulusGO:0071214560.047
regulation of meiosis iGO:006063170.046
intrinsic apoptotic signaling pathwayGO:00971931320.046
ribonucleoside monophosphate metabolic processGO:0009161800.045
genitalia developmentGO:0048806370.045
cleavage furrow formationGO:003608920.045
dna conformation changeGO:0071103370.044
regulation of cellular amine metabolic processGO:0033238200.044
regulation of cytokinesisGO:003246550.043
regulation of dna recombinationGO:0000018340.043
purine ribonucleoside triphosphate metabolic processGO:00092052200.043
spindle organizationGO:0007051280.043
Yeast
cellular ketone metabolic processGO:0042180840.043
double strand break repair via homologous recombinationGO:0000724210.042
rho protein signal transductionGO:0007266320.042
aromatic compound catabolic processGO:00194392860.042
regulation of establishment of protein localizationGO:00702011810.041
regulation of microtubule depolymerizationGO:0031114130.041
membrane organizationGO:00610242450.040
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.040
centriole assemblyGO:009853460.040
regulation of cellular amino acid metabolic processGO:000652150.040
regulation of protein complex disassemblyGO:0043244280.040
cellular protein complex disassemblyGO:0043624360.039
negative regulation of cytoskeleton organizationGO:0051494360.038
neuron migrationGO:00017641220.038
atp catabolic processGO:0006200550.037
mitotic spindle organizationGO:0007052100.037
negative regulation of mitotic cell cycle phase transitionGO:1901991450.036
Yeast Zebrafish Fly
atp metabolic processGO:0046034750.036
regulation of spindle organizationGO:009022420.036
histone modificationGO:00165701590.036
positive regulation of protein kinase activityGO:00458601440.036
microtubule depolymerizationGO:0007019150.035
purine nucleoside monophosphate catabolic processGO:0009128580.035
regulation of cytoskeleton organizationGO:00514931220.035
Yeast
negative regulation of cell cycle processGO:0010948690.035
Yeast Zebrafish Fly
regulation of cellular protein catabolic processGO:1903362610.034
Yeast Fly
negative regulation of cell proliferationGO:00082852960.034
regulation of protein kinase activityGO:00458592320.034
regulation of chromosome segregationGO:0051983210.034
Yeast Fly
cellular protein catabolic processGO:00442571550.034
Yeast Fly
posttranscriptional regulation of gene expressionGO:00106081550.034
establishment of spindle localizationGO:0051293190.034
covalent chromatin modificationGO:00165691630.033
regulation of cell cycle g2 m phase transitionGO:1902749100.033
nucleoside monophosphate catabolic processGO:0009125590.033
establishment or maintenance of cell polarityGO:0007163860.033
response to organonitrogen compoundGO:00102432460.033
oocyte maturationGO:0001556180.033
negative regulation of protein metabolic processGO:00512482820.033
Yeast Fly
oogenesisGO:0048477560.032
wnt signaling pathwayGO:00160551880.032
multicellular organism growthGO:00352641610.031
cellular component assembly involved in morphogenesisGO:00109271390.031
mitotic spindle assembly checkpointGO:000709470.030
Yeast Fly
dna replicationGO:0006260520.030
regulation of protein depolymerizationGO:1901879260.030
ribonucleotide catabolic processGO:00092612080.030
positive regulation of protein modification processGO:00314012990.029
negative regulation of organelle organizationGO:0010639900.029
Yeast Fly
microtubule anchoringGO:003445390.029
Yeast
purine ribonucleoside metabolic processGO:00461282410.029
purine containing compound catabolic processGO:00725232130.029
regulation of t cell activationGO:00508631700.029
regulation of cellular ketone metabolic processGO:0010565660.029
germ cell developmentGO:00072811850.029
meiosis iiGO:000713570.029
female gamete generationGO:0007292740.029
mitotic recombinationGO:000631230.028
protein maturationGO:00516041760.028
Yeast Fly
regulation of kinase activityGO:00435492490.028
positive regulation of nfat protein import into nucleusGO:005153310.028
regulation of mitotic sister chromatid segregationGO:0033047120.027
Yeast Fly
amine metabolic processGO:0009308450.027
protein importGO:00170381010.027
cellularizationGO:000734910.027
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.027
regulation of protein serine threonine kinase activityGO:00719001570.027
negative regulation of intracellular signal transductionGO:19025321670.026
dna endoreduplicationGO:004202340.026
mitotic cell cycle checkpointGO:0007093310.026
Yeast Zebrafish Fly
ribonucleoside triphosphate catabolic processGO:00092031990.026
positive regulation of kinase activityGO:00336741550.026
negative regulation of microtubule depolymerizationGO:0007026130.026
cellular response to organic cyclic compoundGO:0071407870.025
reciprocal dna recombinationGO:0035825160.025
chromosome organization involved in meiosisGO:0070192390.025
male meiosis iGO:0007141160.025
fertilizationGO:00095661270.025
proteolysis involved in cellular protein catabolic processGO:00516031470.025
Yeast Fly
protein localization to organelleGO:00333651850.024
nucleoside catabolic processGO:00091642060.024
regulation of proteolysisGO:00301621640.024
Yeast Fly
regulation of microtubule polymerization or depolymerizationGO:0031110200.024
purine ribonucleoside monophosphate catabolic processGO:0009169570.024
endomembrane system organizationGO:00102561470.024
cilium assemblyGO:0042384810.024
response to organic cyclic compoundGO:00140701980.023
negative regulation of sister chromatid segregationGO:003304670.023
Yeast Fly
positive regulation of cellular amino acid metabolic processGO:004576430.023
regulation of apoptotic signaling pathwayGO:20012331970.023
nucleoside monophosphate metabolic processGO:0009123850.023
regulation of cellular component sizeGO:00325351210.023
intracellular protein transportGO:00068862040.023
positive regulation of cell deathGO:00109422240.022
response to light stimulusGO:00094161350.022
positive regulation of cell developmentGO:00107202370.022
regulation of dna dependent dna replicationGO:009032980.022
cellular response to organonitrogen compoundGO:00714171450.022
regulation of protein catabolic processGO:00421761080.022
Yeast Fly
modification dependent protein catabolic processGO:00199411330.022
Yeast Fly
purine ribonucleoside monophosphate metabolic processGO:0009167800.022
spindle localizationGO:0051653220.022
regulation of protein processingGO:0070613960.022
Yeast Fly
regulation of lymphocyte activationGO:00512492400.021
developmental maturationGO:00217001930.021
gland developmentGO:00487323300.021
chromosome condensationGO:0030261100.021
cell cycle g2 m phase transitionGO:0044839200.021
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.021
microtubule nucleationGO:000702020.021
protein complex disassemblyGO:0043241400.021
small gtpase mediated signal transductionGO:0007264970.020
regulation of nuclear divisionGO:0051783560.020
Yeast Fly
proteasomal protein catabolic processGO:0010498980.020
Yeast Fly
establishment of spindle orientationGO:0051294150.020
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.020
Yeast Fly
spindle midzone assemblyGO:005125510.020
peptidyl amino acid modificationGO:00181933360.020
protein autophosphorylationGO:0046777610.020
ras protein signal transductionGO:0007265770.019
positive regulation of protein phosphorylationGO:00019342420.019
g2 m transition of mitotic cell cycleGO:0000086200.019
protein targetingGO:00066051430.019
endocytosisGO:00068971680.019
regulation of mitotic spindle organizationGO:006023620.019
cell type specific apoptotic processGO:00972852680.019
positive regulation of transferase activityGO:00513471670.019
regulation of intracellular transportGO:00323861590.019
establishment of protein localization to organelleGO:00725941180.019
regulation of cellular catabolic processGO:00313292420.019
Yeast Fly
neural tube formationGO:00018411080.019
regulation of cytokine productionGO:00018172660.019
homeostasis of number of cellsGO:00488722100.019
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.019
Yeast Fly
female meiosis iGO:000714470.018
positive regulation of nuclear divisionGO:0051785270.018
single organism nuclear importGO:1902593950.018
asymmetric neuroblast divisionGO:005505910.018
regulation of wnt signaling pathwayGO:00301111230.018
negative regulation of histone h3 k9 methylationGO:005157340.018
negative regulation of proteolysisGO:0045861740.018
Yeast Fly
negative regulation of protein maturationGO:1903318790.018
Yeast Fly
regulation of anatomical structure sizeGO:00900661780.018
digestive system developmentGO:00551232000.017
muscle cell differentiationGO:00426922610.017
positive regulation of hydrolase activityGO:00513451480.017
blastocyst developmentGO:0001824800.017
regulation of protein maturationGO:1903317960.017
Yeast Fly
negative regulation of protein depolymerizationGO:1901880210.017
negative regulation of ubiquitin protein transferase activityGO:005144430.017
dephosphorylationGO:00163111290.017
negative regulation of molecular functionGO:00440922580.017
regulation of sister chromatid cohesionGO:000706350.017
innate immune responseGO:00450871570.016
meiotic spindle organizationGO:000021290.016
cellular response to radiationGO:0071478280.016
regulation of canonical wnt signaling pathwayGO:0060828820.016
negative regulation of mitotic sister chromatid segregationGO:003304870.016
Yeast Fly
positive regulation of wnt signaling pathwayGO:0030177450.016
actin cytoskeleton organizationGO:00300362200.016
regulation of response to dna damage stimulusGO:2001020340.016
nuclear transportGO:00511691390.016
response to ionizing radiationGO:0010212420.016
macromolecular complex disassemblyGO:0032984430.015
mitotic sister chromatid separationGO:005130690.015
Yeast Fly
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.015
maintenance of location in cellGO:0051651240.015
Yeast
neural tube developmentGO:00219151600.015
single fertilizationGO:0007338820.015
cellular protein complex assemblyGO:00436231160.015
embryonic epithelial tube formationGO:00018381300.015
regulation of cytoplasmic transportGO:19036491120.015
positive regulation of gtp catabolic processGO:0033126850.015
cation transportGO:00068123990.015
positive regulation of protein serine threonine kinase activityGO:00719021060.015
positive regulation of intracellular transportGO:0032388700.015
negative regulation of phosphate metabolic processGO:00459361840.014
t cell activationGO:00421102890.014
regulation of actin filament based processGO:0032970990.014
spermatid developmentGO:00072861080.014
regulation of bindingGO:00510981110.014
protein import into nucleusGO:0006606950.014
negative regulation of cellular protein metabolic processGO:00322692470.014
Yeast Fly
negative regulation of dna replicationGO:000815640.014
regulation of hydrolase activityGO:00513362460.014
dna replication independent nucleosome assemblyGO:000633610.014
spindle assembly involved in female meiosis iGO:000705720.014
positive regulation of cell cycle processGO:0090068610.014
regulation of cellular component biogenesisGO:00440871810.014
regulation of nucleotide metabolic processGO:00061401690.013
positive regulation of chromosome segregationGO:005198440.013
histone acetylationGO:0016573410.013
positive regulation of nucleotide catabolic processGO:0030813880.013
mitotic g2 dna damage checkpointGO:000709580.013
actin filament organizationGO:00070151130.013
cellular lipid metabolic processGO:00442553230.013
dna integrity checkpointGO:0031570280.013
placenta developmentGO:00018901400.013
response to uvGO:0009411440.013
nucleocytoplasmic transportGO:00069131390.013
mapk cascadeGO:00001652810.013
positive regulation of tendon cell differentiationGO:200105110.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
regulation of nuclear cell cycle dna replicationGO:003326220.012
positive regulation of nervous system developmentGO:00519622210.012
metaphase anaphase transition of mitotic cell cycleGO:000709190.012
Yeast Fly
protein localization to nucleusGO:00345041210.012
negative regulation of cellular protein catabolic processGO:1903363220.012
Yeast Fly
cellular response to ionizing radiationGO:0071479110.012
forebrain developmentGO:00309003020.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
neural tube closureGO:0001843900.012
positive regulation of nucleotide metabolic processGO:00459811140.012
b cell activationGO:00421131610.012
divalent metal ion transportGO:00708381720.012
regulation of chromatin organizationGO:1902275570.012
reactive oxygen species metabolic processGO:0072593840.012
regulation of metaphase anaphase transition of cell cycleGO:190209990.012
Yeast Fly
negative regulation of protein complex disassemblyGO:0043242220.012
peptidyl serine phosphorylationGO:0018105740.011
regulation of centriole replicationGO:004659910.011
regulation of asymmetric cell divisionGO:000978640.011
axonogenesisGO:00074092740.011
protein polyubiquitinationGO:0000209330.011
regulation of protein targetingGO:1903533610.011
cell adhesionGO:00071553290.011
regulation of mapk cascadeGO:00434082480.011
spermatid differentiationGO:00485151150.011
regulation of endopeptidase activityGO:0052548890.011
nuclear importGO:0051170950.011
chromatin remodeling at centromereGO:003105520.011
regulation of rho gtpase activityGO:0032319580.011
regulation of intracellular protein transportGO:0033157820.011
regulation of cell activationGO:00508652890.011
epithelial cell proliferationGO:00506731740.011
blood vessel morphogenesisGO:00485142850.011
leukocyte proliferationGO:00706611720.011
regulation of mitotic sister chromatid separationGO:0010965120.011
Yeast Fly
cellular response to lipidGO:00713961450.011
regulation of neuron differentiationGO:00456642810.011
regulation of leukocyte apoptotic processGO:2000106560.011
synaptonemal complex assemblyGO:0007130130.011
chromatin assembly or disassemblyGO:0006333160.011
regulation of t cell proliferationGO:0042129920.011
tube closureGO:0060606910.011
macromolecule methylationGO:00434141200.011
regulation of protein stabilityGO:0031647520.010
positive regulation of intracellular protein transportGO:0090316420.010
cellular response to cytokine stimulusGO:00713451890.010
regulation of purine nucleotide metabolic processGO:19005421690.010
protein polymerizationGO:0051258570.010
lymphocyte differentiationGO:00300982420.010
intracellular mrna localizationGO:000829840.010
cellular response to biotic stimulusGO:0071216920.010
regulation of cell projection organizationGO:00313442060.010
protein modification by small protein conjugationGO:00324461870.010
positive regulation of cell divisionGO:0051781310.010
postreplication repairGO:000630150.010
negative regulation of nuclear divisionGO:0051784190.010
Yeast Fly
regulation of cell motilityGO:20001452360.010

Ttk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.037
organ system cancerDOID:005068600.037
cancerDOID:16200.037
thoracic cancerDOID:509300.026
disease of anatomical entityDOID:700.026
immune system diseaseDOID:291400.026
breast cancerDOID:161200.018
large intestine cancerDOID:567200.010
colon cancerDOID:21900.010
colorectal cancerDOID:925600.010
gastrointestinal system cancerDOID:311900.010
intestinal cancerDOID:1015500.010
colon carcinomaDOID:152000.010