Mus musculus

0 known processes

Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

(Aliases: Dip3b)

Appl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.091
cellular ketone metabolic processGO:0042180840.070
regulation of cellular amino acid metabolic processGO:000652150.067
cellular amine metabolic processGO:0044106440.066
negative regulation of cellular protein metabolic processGO:00322692470.064
histone lysine methylationGO:0034968500.054
peptidyl amino acid modificationGO:00181933360.051
nucleobase containing small molecule metabolic processGO:00550863520.051
response to peptide hormoneGO:00434341270.050
actin cytoskeleton organizationGO:00300362200.049
regulation of cellular ketone metabolic processGO:0010565660.047
amine metabolic processGO:0009308450.045
organelle localizationGO:00516401790.043
regionalizationGO:00030023370.042
negative regulation of cellular component organizationGO:00511291940.042
response to organonitrogen compoundGO:00102432460.041
regulation of apoptotic signaling pathwayGO:20012331970.040
cellular nitrogen compound catabolic processGO:00442702800.038
carbohydrate metabolic processGO:00059752300.038
reactive oxygen species metabolic processGO:0072593840.038
dna metabolic processGO:00062593030.038
urogenital system developmentGO:00016552610.038
dephosphorylationGO:00163111290.038
cation transportGO:00068123990.037
primary neural tube formationGO:0014020950.037
posttranscriptional regulation of gene expressionGO:00106081550.037
embryonic epithelial tube formationGO:00018381300.037
regulation of reactive oxygen species metabolic processGO:2000377400.036
cell type specific apoptotic processGO:00972852680.036
stem cell developmentGO:00488642190.035
negative regulation of protein metabolic processGO:00512482820.035
cellular response to cytokine stimulusGO:00713451890.034
cellular response to hormone stimulusGO:00328701500.032
small gtpase mediated signal transductionGO:0007264970.032
cellular carbohydrate metabolic processGO:00442621190.032
cellular lipid metabolic processGO:00442553230.032
nucleotide metabolic processGO:00091173320.032
locomotory behaviorGO:00076261950.032
synaptic transmissionGO:00072683290.032
cellular macromolecule catabolic processGO:00442652060.031
g protein coupled receptor signaling pathwayGO:00071862430.031
cellular response to organonitrogen compoundGO:00714171450.031
establishment of organelle localizationGO:00516561220.030
regulation of organelle organizationGO:00330432890.030
cellular protein complex assemblyGO:00436231160.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
regulation of cellular amine metabolic processGO:0033238200.030
purine nucleoside metabolic processGO:00422782410.030
positive regulation of protein modification processGO:00314012990.029
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
positive regulation of apoptotic processGO:00430652170.029
positive regulation of cellular amine metabolic processGO:003324050.029
regulation of hydrolase activityGO:00513362460.028
organophosphate catabolic processGO:00464342320.028
cellular response to dna damage stimulusGO:00069742070.028
guanosine containing compound catabolic processGO:19010691440.027
negative regulation of nervous system developmentGO:00519611560.027
chromatin organizationGO:00063252060.027
vesicle localizationGO:0051648860.027
homeostasis of number of cellsGO:00488722100.027
cytokine productionGO:00018163190.026
organonitrogen compound catabolic processGO:19015652640.026
regulation of intracellular transportGO:00323861590.026
male gamete generationGO:00482322850.026
glucose homeostasisGO:00425931280.026
regulation of cell activationGO:00508652890.025
maintenance of locationGO:0051235890.025
chromatin modificationGO:00165681870.025
ribonucleoside metabolic processGO:00091192450.025
phospholipid biosynthetic processGO:0008654360.025
hexose metabolic processGO:0019318980.025
regulation of protein localizationGO:00328802310.025
compound eye developmentGO:004874910.024
ribonucleoside catabolic processGO:00424542060.024
epithelial tube morphogenesisGO:00605623030.024
regulation of transferase activityGO:00513382630.024
heterocycle catabolic processGO:00467002800.024
response to light stimulusGO:00094161350.023
positive regulation of gtp catabolic processGO:0033126850.023
renal system developmentGO:00720012250.023
negative regulation of protein modification processGO:00314001630.023
regulation of membrane potentialGO:00423911920.022
ribonucleoside triphosphate catabolic processGO:00092031990.022
regulation of lymphocyte activationGO:00512492400.022
cellular response to organic cyclic compoundGO:0071407870.022
protein modification by small protein conjugationGO:00324461870.022
positive regulation of cell deathGO:00109422240.022
ras protein signal transductionGO:0007265770.022
purine nucleoside triphosphate metabolic processGO:00091442260.021
neural tube formationGO:00018411080.021
purine nucleotide metabolic processGO:00061633020.021
peptidyl tyrosine modificationGO:00182121450.021
macromolecule catabolic processGO:00090572810.021
transmembrane transportGO:00550854120.021
regulation of cellular component biogenesisGO:00440871810.020
ribonucleotide metabolic processGO:00092592910.020
negative regulation of cell proliferationGO:00082852960.020
regulation of homeostatic processGO:00328441820.020
organic cyclic compound catabolic processGO:19013612950.020
aromatic compound catabolic processGO:00194392860.020
muscle cell differentiationGO:00426922610.020
microtubule based processGO:00070172360.020
rna processingGO:00063961050.020
rhythmic processGO:00485111740.020
lipid biosynthetic processGO:00086101790.020
positive regulation of organelle organizationGO:00106381280.019
purine containing compound metabolic processGO:00725213110.019
protein modification by small protein conjugation or removalGO:00706472070.019
cytokine mediated signaling pathwayGO:00192211150.019
carbohydrate derivative biosynthetic processGO:19011371830.019
embryonic organ morphogenesisGO:00485622760.019
inorganic ion transmembrane transportGO:00986602340.019
purine nucleoside catabolic processGO:00061522050.019
divalent inorganic cation transportGO:00725111780.019
protein catabolic processGO:00301632210.019
positive regulation of protein phosphorylationGO:00019342420.019
positive regulation of programmed cell deathGO:00430682180.019
positive regulation of nervous system developmentGO:00519622210.019
nucleoside phosphate metabolic processGO:00067533380.019
membrane organizationGO:00610242450.018
gland developmentGO:00487323300.018
generation of precursor metabolites and energyGO:00060911030.018
apoptotic signaling pathwayGO:00971903060.018
cellular response to lipidGO:00713961450.018
mitotic cell cycleGO:00002781950.018
digestive system developmentGO:00551232000.018
regulation of cytokine productionGO:00018172660.018
methylationGO:00322591340.018
peptidyl tyrosine phosphorylationGO:00181081430.018
negative regulation of cell developmentGO:00107211690.018
dna repairGO:00062811070.018
glycosyl compound catabolic processGO:19016582060.018
leukocyte differentiationGO:00025213420.018
regulation of cellular catabolic processGO:00313292420.018
nucleotide catabolic processGO:00091662170.018
myeloid cell differentiationGO:00300992330.018
positive regulation of protein catabolic processGO:0045732600.017
cytoplasmic transportGO:00164822340.017
response to inorganic substanceGO:0010035960.017
response to oxygen levelsGO:0070482620.017
negative regulation of organelle organizationGO:0010639900.017
response to organic cyclic compoundGO:00140701980.017
ribonucleoside triphosphate metabolic processGO:00091992200.017
tube formationGO:00351481400.017
glycerophospholipid metabolic processGO:0006650710.017
regulation of cell cycleGO:00517262810.017
regulation of anatomical structure sizeGO:00900661780.017
spermatid differentiationGO:00485151150.017
nucleoside phosphate catabolic processGO:19012922220.017
organophosphate biosynthetic processGO:00904071220.017
establishment of vesicle localizationGO:0051650810.017
regulation of protein complex assemblyGO:0043254830.017
stem cell differentiationGO:00488632680.017
ribose phosphate metabolic processGO:00196932910.017
inorganic cation transmembrane transportGO:00986622070.017
exocytosisGO:00068871210.017
negative regulation of intracellular signal transductionGO:19025321670.017
regulation of protein serine threonine kinase activityGO:00719001570.017
ribonucleotide catabolic processGO:00092612080.017
protein targetingGO:00066051430.016
cation transmembrane transportGO:00986552660.016
circulatory system processGO:00030131970.016
actin filament organizationGO:00070151130.016
ion transmembrane transportGO:00342203610.016
purine ribonucleotide metabolic processGO:00091502900.016
carbohydrate homeostasisGO:00335001280.016
glycoprotein metabolic processGO:00091001160.016
action potentialGO:0001508780.016
kidney developmentGO:00018222130.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
response to peptideGO:19016521360.016
spermatogenesisGO:00072832840.016
regulation of cytoskeleton organizationGO:00514931220.016
muscle tissue developmentGO:00605373080.016
purine nucleotide catabolic processGO:00061952110.016
cell adhesionGO:00071553290.016
oxidation reduction processGO:00551143420.015
positive regulation of cellular catabolic processGO:00313311480.015
regulation of secretionGO:00510462740.015
regulation of metal ion transportGO:00109591060.015
cellular response to lipopolysaccharideGO:0071222770.015
cellular response to molecule of bacterial originGO:0071219830.015
purine ribonucleoside metabolic processGO:00461282410.015
intracellular protein transportGO:00068862040.015
sensory perceptionGO:00076002450.015
tissue homeostasisGO:00018941150.015
protein ubiquitinationGO:00165671710.015
t cell activationGO:00421102890.015
chemotaxisGO:00069352470.015
nitrogen compound transportGO:00717052710.015
regulation of neuron differentiationGO:00456642810.015
negative regulation of mitotic cell cycleGO:0045930580.015
hormone mediated signaling pathwayGO:0009755230.015
viral gene expressionGO:001908030.015
neuronal action potentialGO:0019228540.015
regulation of vesicle mediated transportGO:00606271390.015
histone h2a ubiquitinationGO:003352230.015
positive regulation of cell adhesionGO:0045785800.014
axonogenesisGO:00074092740.014
neuron deathGO:00709971540.014
regulation of t cell activationGO:00508631700.014
mapk cascadeGO:00001652810.014
germ cell developmentGO:00072811850.014
negative regulation of phosphorylationGO:00423261660.014
glycosyl compound metabolic processGO:19016572460.014
regulation of neuron deathGO:19012141340.014
positive regulation of leukocyte differentiationGO:1902107860.014
regulation of nucleoside metabolic processGO:00091181300.014
positive regulation of nucleoside metabolic processGO:0045979910.014
cellular chemical homeostasisGO:00550822150.014
carbohydrate derivative catabolic processGO:19011362310.014
regulation of gtp catabolic processGO:00331241130.014
negative regulation of cell cycleGO:00457861230.014
regulation of ion transportGO:00432692150.014
negative regulation of cellular amine metabolic processGO:003323910.014
protein localization to membraneGO:00726571080.014
regulation of mapk cascadeGO:00434082480.014
negative regulation of phosphate metabolic processGO:00459361840.014
leukocyte mediated immunityGO:00024431740.014
neural tube closureGO:0001843900.013
cellular homeostasisGO:00197252400.013
organic hydroxy compound metabolic processGO:19016152030.013
multicellular organism growthGO:00352641610.013
response to nutrient levelsGO:00316671090.013
cellular response to biotic stimulusGO:0071216920.013
regulation of cell cycle processGO:00105641600.013
regulation of secretion by cellGO:19035302490.013
nucleoside metabolic processGO:00091162460.013
cytoskeleton dependent intracellular transportGO:0030705500.013
regulation of proteolysisGO:00301621640.013
actin filament polymerizationGO:0030041440.013
wnt signaling pathwayGO:00160551880.013
rna catabolic processGO:0006401290.013
cation homeostasisGO:00550802120.013
protein maturationGO:00516041760.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
regulation of cell adhesionGO:00301551540.013
regulation of kinase activityGO:00435492490.013
regulation of protein transportGO:00512231630.013
regulation of protein catabolic processGO:00421761080.013
immune effector processGO:00022523210.013
notch signaling pathwayGO:0007219710.013
plasma membrane organizationGO:0007009900.013
multicellular organismal homeostasisGO:00488711640.012
dorsal ventral axon guidanceGO:003356330.012
rho protein signal transductionGO:0007266320.012
nucleoside triphosphate metabolic processGO:00091412300.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
positive regulation of cell motilityGO:20001471160.012
nucleoside catabolic processGO:00091642060.012
positive regulation of neuron differentiationGO:00456661410.012
response to radiationGO:00093141650.012
dendrite developmentGO:00163581150.012
regulation of excitatory postsynaptic membrane potentialGO:0060079410.012
lipid localizationGO:00108761260.012
protein processingGO:00164851630.012
covalent chromatin modificationGO:00165691630.012
epithelial tube formationGO:00721751300.012
negative regulation of molecular functionGO:00440922580.012
spermatid developmentGO:00072861080.012
gtp metabolic processGO:00460391440.012
morphogenesis of embryonic epitheliumGO:00163311590.012
glucose metabolic processGO:0006006920.012
myeloid cell homeostasisGO:00022621140.012
positive regulation of apoptotic signaling pathwayGO:2001235950.012
regulation of lymphocyte differentiationGO:00456191070.012
mitotic cell cycle processGO:19030471590.012
tumor necrosis factor superfamily cytokine productionGO:0071706510.012
carbon catabolite activation of transcriptionGO:004599140.012
extracellular structure organizationGO:00430621480.012
regulation of cellular component sizeGO:00325351210.012
cellular ion homeostasisGO:00068731650.012
regulation of carbohydrate metabolic processGO:0006109750.012
cell recognitionGO:0008037830.012
negative regulation of immune system processGO:00026832090.012
carbon catabolite regulation of transcriptionGO:004599040.012
regulation of protein kinase activityGO:00458592320.012
smoothened signaling pathwayGO:00072241050.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
epithelial cell proliferationGO:00506731740.012
divalent metal ion transportGO:00708381720.012
cell cell recognitionGO:0009988440.012
cellular response to nutrient levelsGO:0031669640.012
positive regulation of cell developmentGO:00107202370.012
digestive tract developmentGO:00485651900.012
purine ribonucleoside catabolic processGO:00461302050.012
response to growth factorGO:00708481980.012
learning or memoryGO:00076111480.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
microtubule based transportGO:0010970500.011
purine ribonucleotide catabolic processGO:00091542080.011
reactive oxygen species biosynthetic processGO:190340980.011
protein localization to plasma membraneGO:0072659570.011
negative regulation of neuron differentiationGO:00456651010.011
adult behaviorGO:00305341350.011
anatomical structure homeostasisGO:00602491450.011
regulation of leukocyte differentiationGO:19021051590.011
mitochondrion organizationGO:00070051340.011
transmission of nerve impulseGO:0019226760.011
retrograde transport endosome to golgiGO:004214720.011
response to uvGO:0009411440.011
endocytosisGO:00068971680.011
positive regulation of hydrolase activityGO:00513451480.011
lateral inhibitionGO:004633110.011
sequestering of metal ionGO:0051238190.011
positive regulation of nucleotide catabolic processGO:0030813880.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
regulation of actin filament based processGO:0032970990.011
regulation of ras gtpase activityGO:0032318880.011
myeloid leukocyte differentiationGO:00025731190.011
blood circulationGO:00080151950.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
carbohydrate biosynthetic processGO:0016051740.011
histone modificationGO:00165701590.011
regulation of neuron apoptotic processGO:00435231220.011
neuromuscular process controlling balanceGO:0050885590.011
regulation of transcription from rna polymerase iii promoterGO:000635920.011
cellular response to growth factor stimulusGO:00713631970.011
nucleoside triphosphate catabolic processGO:00091432050.010
cellular metal ion homeostasisGO:00068751510.010
protein methylationGO:0006479810.010
neuron apoptotic processGO:00514021420.010
anion transportGO:00068201770.010
regulation of reactive oxygen species biosynthetic processGO:190342620.010
guanosine containing compound metabolic processGO:19010681440.010
small molecule catabolic processGO:0044282710.010
carboxylic acid transportGO:00469421000.010
regulation of establishment of protein localizationGO:00702011810.010
translationGO:0006412930.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
multicellular organismal signalingGO:0035637910.010
regulation of feeding behaviorGO:006025930.010
bmp signaling pathwayGO:0030509930.010
muscle system processGO:00030121410.010
adaptive immune responseGO:00022501550.010
negative regulation of cytokine productionGO:0001818840.010
multi multicellular organism processGO:00447061090.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
regulation of lipid metabolic processGO:00192161180.010
single fertilizationGO:0007338820.010
negative regulation of phosphorus metabolic processGO:00105631840.010
polysaccharide metabolic processGO:0005976390.010

Appl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.037
inherited metabolic disorderDOID:65500.022
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
organ system cancerDOID:005068600.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
central nervous system diseaseDOID:33100.013