Mus musculus

0 known processes

D2hgdh

D-2-hydroxyglutarate dehydrogenase

(Aliases: AI325464,AA408776,AA408778)

D2hgdh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.074
Rat
cellular amino acid metabolic processGO:00065201030.073
cellular ketone metabolic processGO:0042180840.046
regulation of cellular ketone metabolic processGO:0010565660.043
cellular amine metabolic processGO:0044106440.040
cellular lipid metabolic processGO:00442553230.039
regulation of cellular amino acid metabolic processGO:000652150.038
carboxylic acid biosynthetic processGO:0046394860.037
amine metabolic processGO:0009308450.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
cellular nitrogen compound catabolic processGO:00442702800.035
cytokine productionGO:00018163190.033
nucleoside phosphate metabolic processGO:00067533380.033
organic cyclic compound catabolic processGO:19013612950.033
aromatic compound catabolic processGO:00194392860.033
cation transportGO:00068123990.032
nucleobase containing small molecule metabolic processGO:00550863520.032
dna metabolic processGO:00062593030.032
cellular response to lipidGO:00713961450.032
response to organonitrogen compoundGO:00102432460.032
organic acid biosynthetic processGO:0016053860.031
nitrogen compound transportGO:00717052710.030
heterocycle catabolic processGO:00467002800.030
regulation of cytokine productionGO:00018172660.029
transmembrane transportGO:00550854120.028
regulation of cellular amine metabolic processGO:0033238200.028
cellular response to organonitrogen compoundGO:00714171450.026
lipid biosynthetic processGO:00086101790.025
nucleotide metabolic processGO:00091173320.025
alpha amino acid metabolic processGO:1901605590.025
positive regulation of cellular amine metabolic processGO:003324050.025
cofactor metabolic processGO:0051186800.024
ribonucleoside metabolic processGO:00091192450.023
purine ribonucleoside metabolic processGO:00461282410.023
nucleoside triphosphate metabolic processGO:00091412300.023
cellular response to dna damage stimulusGO:00069742070.022
glycosyl compound metabolic processGO:19016572460.022
small molecule biosynthetic processGO:00442831320.022
fatty acid metabolic processGO:00066311210.021
coenzyme metabolic processGO:0006732520.021
ribonucleotide metabolic processGO:00092592910.021
immune effector processGO:00022523210.020
regulation of cell activationGO:00508652890.020
regulation of transferase activityGO:00513382630.020
multicellular organismal homeostasisGO:00488711640.020
regulation of lymphocyte activationGO:00512492400.020
regulation of defense responseGO:00313472330.020
homeostasis of number of cellsGO:00488722100.020
protein localization to organelleGO:00333651850.020
purine nucleotide metabolic processGO:00061633020.020
organonitrogen compound catabolic processGO:19015652640.020
macromolecule catabolic processGO:00090572810.020
organic anion transportGO:00157111370.020
peptidyl amino acid modificationGO:00181933360.019
organic acid transportGO:00158491010.019
response to molecule of bacterial originGO:00022371430.019
ion transmembrane transportGO:00342203610.019
negative regulation of protein metabolic processGO:00512482820.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
monocarboxylic acid metabolic processGO:00327871910.019
carboxylic acid catabolic processGO:0046395510.018
ribose phosphate metabolic processGO:00196932910.018
cation transmembrane transportGO:00986552660.018
regulation of protein transportGO:00512231630.018
purine ribonucleotide metabolic processGO:00091502900.018
spermatogenesisGO:00072832840.018
positive regulation of protein modification processGO:00314012990.018
cellular response to hormone stimulusGO:00328701500.018
response to lipopolysaccharideGO:00324961280.018
sulfur compound metabolic processGO:00067901000.018
purine containing compound metabolic processGO:00725213110.018
dna repairGO:00062811070.018
cellular response to cytokine stimulusGO:00713451890.017
purine ribonucleoside catabolic processGO:00461302050.017
leukocyte differentiationGO:00025213420.017
t cell activationGO:00421102890.017
protein modification by small protein conjugation or removalGO:00706472070.017
innate immune responseGO:00450871570.017
negative regulation of immune system processGO:00026832090.017
cell type specific apoptotic processGO:00972852680.017
ribonucleoside catabolic processGO:00424542060.017
nucleoside metabolic processGO:00091162460.017
response to peptide hormoneGO:00434341270.016
purine nucleoside catabolic processGO:00061522050.016
anatomical structure homeostasisGO:00602491450.016
glycosyl compound catabolic processGO:19016582060.016
regulation of hormone levelsGO:00108172110.016
response to peptideGO:19016521360.016
ribonucleotide catabolic processGO:00092612080.016
regulation of cellular catabolic processGO:00313292420.016
sensory perceptionGO:00076002450.016
protein maturationGO:00516041760.016
regulation of organelle organizationGO:00330432890.016
reactive oxygen species metabolic processGO:0072593840.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of homeostatic processGO:00328441820.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
response to insulinGO:00328681000.016
organonitrogen compound biosynthetic processGO:19015661920.016
regulation of secretionGO:00510462740.016
organophosphate catabolic processGO:00464342320.016
intracellular protein transportGO:00068862040.015
response to organic cyclic compoundGO:00140701980.015
nucleoside phosphate catabolic processGO:19012922220.015
carbohydrate homeostasisGO:00335001280.015
cellular response to biotic stimulusGO:0071216920.015
myeloid leukocyte differentiationGO:00025731190.015
response to acid chemicalGO:00011011110.015
tissue homeostasisGO:00018941150.015
carbohydrate derivative catabolic processGO:19011362310.015
regulation of apoptotic signaling pathwayGO:20012331970.015
purine ribonucleotide catabolic processGO:00091542080.015
inflammatory responseGO:00069542440.015
protein modification by small protein conjugationGO:00324461870.015
apoptotic signaling pathwayGO:00971903060.015
protein ubiquitinationGO:00165671710.015
cellular macromolecule catabolic processGO:00442652060.015
nucleoside catabolic processGO:00091642060.015
response to radiationGO:00093141650.015
anion transportGO:00068201770.015
carbohydrate derivative biosynthetic processGO:19011371830.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
negative regulation of cell proliferationGO:00082852960.014
cellular response to molecule of bacterial originGO:0071219830.014
regulation of membrane potentialGO:00423911920.014
alpha amino acid biosynthetic processGO:1901607150.014
regulation of establishment of protein localizationGO:00702011810.014
organic acid catabolic processGO:0016054510.014
cellular response to lipopolysaccharideGO:0071222770.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
regulation of kinase activityGO:00435492490.014
ras protein signal transductionGO:0007265770.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
glycoprotein metabolic processGO:00091001160.014
negative regulation of cellular protein metabolic processGO:00322692470.014
negative regulation of phosphate metabolic processGO:00459361840.014
organic hydroxy compound metabolic processGO:19016152030.014
protein targetingGO:00066051430.014
cytoplasmic transportGO:00164822340.014
positive regulation of programmed cell deathGO:00430682180.014
carboxylic acid transportGO:00469421000.014
male gamete generationGO:00482322850.014
carbohydrate metabolic processGO:00059752300.014
positive regulation of cytokine productionGO:00018191740.014
nuclear transportGO:00511691390.013
regulation of cell cycleGO:00517262810.013
positive regulation of protein phosphorylationGO:00019342420.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
gland developmentGO:00487323300.013
mitochondrion organizationGO:00070051340.013
positive regulation of cell deathGO:00109422240.013
monocarboxylic acid biosynthetic processGO:0072330610.013
limb developmentGO:00601731660.013
regulation of protein localizationGO:00328802310.013
lymphocyte proliferationGO:00466511640.013
negative regulation of cellular amine metabolic processGO:003323910.013
nucleocytoplasmic transportGO:00069131390.013
fat cell differentiationGO:00454441600.013
cation homeostasisGO:00550802120.013
regulation of protein kinase activityGO:00458592320.013
thermosensory behaviorGO:004004010.013
regulation of t cell activationGO:00508631700.013
purine nucleoside metabolic processGO:00422782410.013
microtubule based processGO:00070172360.013
translationGO:0006412930.013
regulation of response to woundingGO:19030341890.013
protein localization to nucleusGO:00345041210.013
cellular response to peptide hormone stimulusGO:0071375920.013
nucleotide catabolic processGO:00091662170.013
appendage developmentGO:00487361660.013
cellular homeostasisGO:00197252400.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
small gtpase mediated signal transductionGO:0007264970.013
protein processingGO:00164851630.013
regulation of intracellular transportGO:00323861590.013
nucleoside monophosphate metabolic processGO:0009123850.012
negative regulation of protein modification processGO:00314001630.012
regulation of ion transportGO:00432692150.012
fertilizationGO:00095661270.012
mitotic cell cycleGO:00002781950.012
positive regulation of apoptotic processGO:00430652170.012
cellular metal ion homeostasisGO:00068751510.012
regulation of mapk cascadeGO:00434082480.012
compound eye developmentGO:004874910.012
cellular response to acid chemicalGO:0071229680.012
multicellular organism growthGO:00352641610.012
dephosphorylationGO:00163111290.012
establishment of protein localization to organelleGO:00725941180.012
purine nucleotide catabolic processGO:00061952110.012
purine containing compound catabolic processGO:00725232130.012
regulation of secretion by cellGO:19035302490.012
inorganic cation transmembrane transportGO:00986622070.012
interleukin 8 productionGO:003263740.012
regulation of cellular response to stressGO:00801351590.012
ribonucleoside bisphosphate metabolic processGO:003387590.012
negative regulation of intracellular signal transductionGO:19025321670.012
anion transmembrane transportGO:0098656710.012
metal ion homeostasisGO:00550651890.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
amide transportGO:00428861380.012
divalent inorganic cation transportGO:00725111780.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
negative regulation of phosphorus metabolic processGO:00105631840.012
regulation of leukocyte differentiationGO:19021051590.012
wnt signaling pathwayGO:00160551880.012
reactive nitrogen species metabolic processGO:200105700.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
rhythmic processGO:00485111740.011
synaptic transmissionGO:00072683290.011
embryonic epithelial tube formationGO:00018381300.011
cellular chemical homeostasisGO:00550822150.011
epithelial tube morphogenesisGO:00605623030.011
negative regulation of protein phosphorylationGO:00019331260.011
regulation of hydrolase activityGO:00513362460.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
dicarboxylic acid metabolic processGO:0043648180.011
reactive oxygen species biosynthetic processGO:190340980.011
protein importGO:00170381010.011
regulation of cytoplasmic transportGO:19036491120.011
regulation of lymphocyte proliferationGO:00506701170.011
dna catabolic process endonucleolyticGO:0000737150.011
positive regulation of defense responseGO:00313491240.011
lateral inhibitionGO:004633110.011
negative regulation of cellular component organizationGO:00511291940.011
membrane organizationGO:00610242450.011
maintenance of locationGO:0051235890.011
regulation of interleukin 8 productionGO:003267730.011
male anatomical structure morphogenesisGO:009059840.011
adult behaviorGO:00305341350.011
small molecule catabolic processGO:0044282710.011
negative regulation of cell cycleGO:00457861230.011
cellular carbohydrate metabolic processGO:00442621190.011
g protein coupled receptor signaling pathwayGO:00071862430.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
defense response to other organismGO:00985421970.011
muscle tissue developmentGO:00605373080.011
neuron deathGO:00709971540.011
lymphocyte differentiationGO:00300982420.011
nuclear divisionGO:00002801580.011
respiratory tube developmentGO:00303231670.011
mapk cascadeGO:00001652810.011
positive regulation of hydrolase activityGO:00513451480.011
germ cell developmentGO:00072811850.011
rho protein signal transductionGO:0007266320.011
cellular amino acid biosynthetic processGO:0008652220.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
cellular response to peptideGO:1901653920.011
skin developmentGO:00435882200.011
tube formationGO:00351481400.011
regulation of feeding behaviorGO:006025930.011
hematopoietic progenitor cell differentiationGO:00022441430.011
glucose homeostasisGO:00425931280.011
skeletal muscle organ developmentGO:00605381630.011
protein catabolic processGO:00301632210.010
striated muscle tissue developmentGO:00147062930.010
methylationGO:00322591340.010
positive regulation of cell activationGO:00508671580.010
connective tissue developmentGO:00614481790.010
response to light stimulusGO:00094161350.010
regulation of inflammatory responseGO:00507271470.010
peptide transportGO:00158331330.010
cellular amide metabolic processGO:0043603580.010
cellular amino acid catabolic processGO:0009063250.010
amino acid transportGO:0006865610.010
steroid metabolic processGO:00082021190.010
positive regulation of cell developmentGO:00107202370.010
leukocyte proliferationGO:00706611720.010
positive regulation of secretion by cellGO:19035321140.010
alpha amino acid catabolic processGO:1901606180.010
purine nucleoside triphosphate catabolic processGO:00091462030.010
cellular modified amino acid metabolic processGO:0006575630.010
negative regulation of phosphorylationGO:00423261660.010
glycosylationGO:0070085620.010
myeloid cell differentiationGO:00300992330.010
locomotory behaviorGO:00076261950.010
positive regulation of interleukin 8 productionGO:003275720.010
inorganic ion transmembrane transportGO:00986602340.010

D2hgdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.030
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
disease of cellular proliferationDOID:1456600.017
central nervous system diseaseDOID:33100.016
organ system cancerDOID:005068600.015
cancerDOID:16200.015
inherited metabolic disorderDOID:65500.015
sensory system diseaseDOID:005015500.015