Mus musculus

46 known processes

Slc1a1

solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

(Aliases: EAAT3,EAAC2,EAAC1,MEAAC1,D130048G10Rik)

Slc1a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072683290.205
Mouse
cation transportGO:00068123990.204
ion transmembrane transportGO:00342203610.202
inorganic cation transmembrane transportGO:00986622070.180
inorganic ion transmembrane transportGO:00986602340.171
anion transportGO:00068201770.167
transmembrane transportGO:00550854120.159
purine nucleotide catabolic processGO:00061952110.151
carbohydrate derivative catabolic processGO:19011362310.146
gtp metabolic processGO:00460391440.141
organonitrogen compound catabolic processGO:19015652640.135
organophosphate catabolic processGO:00464342320.130
nucleoside metabolic processGO:00091162460.126
purine ribonucleoside metabolic processGO:00461282410.118
nucleotide metabolic processGO:00091173320.114
nucleoside triphosphate catabolic processGO:00091432050.113
cation transmembrane transportGO:00986552660.113
ribose phosphate metabolic processGO:00196932910.112
ribonucleoside metabolic processGO:00091192450.109
purine ribonucleotide catabolic processGO:00091542080.108
purine nucleoside triphosphate metabolic processGO:00091442260.104
purine containing compound metabolic processGO:00725213110.103
cellular amino acid metabolic processGO:00065201030.101
Mouse
purine containing compound catabolic processGO:00725232130.100
nucleoside phosphate catabolic processGO:19012922220.100
ribonucleoside catabolic processGO:00424542060.099
glycosyl compound metabolic processGO:19016572460.098
heterocycle catabolic processGO:00467002800.098
regulation of nucleoside metabolic processGO:00091181300.097
ribonucleotide catabolic processGO:00092612080.097
purine nucleoside metabolic processGO:00422782410.097
aromatic compound catabolic processGO:00194392860.095
neuronal action potentialGO:0019228540.095
ribonucleoside triphosphate metabolic processGO:00091992200.093
glycosyl compound catabolic processGO:19016582060.093
endocytosisGO:00068971680.092
ribonucleoside triphosphate catabolic processGO:00092031990.090
transmission of nerve impulseGO:0019226760.089
nucleoside triphosphate metabolic processGO:00091412300.089
ras protein signal transductionGO:0007265770.088
purine ribonucleoside catabolic processGO:00461302050.088
purine nucleotide metabolic processGO:00061633020.088
anion transmembrane transportGO:0098656710.086
cellular nitrogen compound catabolic processGO:00442702800.085
nucleoside phosphate metabolic processGO:00067533380.084
nucleoside catabolic processGO:00091642060.082
nucleotide catabolic processGO:00091662170.079
regulation of hydrolase activityGO:00513362460.077
negative regulation of phosphate metabolic processGO:00459361840.075
organic cyclic compound catabolic processGO:19013612950.075
purine ribonucleoside triphosphate catabolic processGO:00092071990.074
cellular ketone metabolic processGO:0042180840.074
positive regulation of cellular amino acid metabolic processGO:004576430.073
purine nucleoside triphosphate catabolic processGO:00091462030.073
purine nucleoside catabolic processGO:00061522050.073
gtp catabolic processGO:00061841430.068
nucleobase containing small molecule metabolic processGO:00550863520.067
regulation of membrane potentialGO:00423911920.067
Mouse
sodium ion transmembrane transportGO:0035725490.066
organic acid transportGO:00158491010.065
purine ribonucleoside triphosphate metabolic processGO:00092052200.064
inorganic anion transmembrane transportGO:0098661290.062
positive regulation of cellular amine metabolic processGO:003324050.061
regulation of ion transportGO:00432692150.060
multicellular organismal signalingGO:0035637910.059
ribonucleotide metabolic processGO:00092592910.059
purine ribonucleotide metabolic processGO:00091502900.058
action potentialGO:0001508780.057
guanosine containing compound catabolic processGO:19010691440.057
nitrogen compound transportGO:00717052710.056
carbohydrate transportGO:0008643620.052
Mouse
amino acid transmembrane transportGO:0003333370.050
plasma membrane organizationGO:0007009900.050
regulation of cellular amine metabolic processGO:0033238200.049
regulation of cellular ketone metabolic processGO:0010565660.049
sensory perceptionGO:00076002450.047
Mouse
small gtpase mediated signal transductionGO:0007264970.047
muscle system processGO:00030121410.047
divalent inorganic cation transportGO:00725111780.046
guanosine containing compound metabolic processGO:19010681440.046
regulation of purine nucleotide catabolic processGO:00331211220.045
organic acid biosynthetic processGO:0016053860.045
Mouse
mapk cascadeGO:00001652810.045
regulation of purine nucleotide metabolic processGO:19005421690.044
glucose transportGO:0015758560.042
Mouse
regulation of gtp catabolic processGO:00331241130.041
neuromuscular processGO:0050905990.041
Mouse
regulation of cellular amino acid metabolic processGO:000652150.041
negative regulation of phosphorus metabolic processGO:00105631840.040
inorganic anion transportGO:0015698430.040
sodium ion transportGO:0006814730.038
protein localization to membraneGO:00726571080.038
cellular protein complex assemblyGO:00436231160.038
g protein coupled receptor signaling pathwayGO:00071862430.038
chloride transmembrane transportGO:1902476240.037
macromolecule catabolic processGO:00090572810.037
cellular lipid metabolic processGO:00442553230.037
calcium ion transmembrane transportGO:0070588850.037
amino acid transportGO:0006865610.036
chloride transportGO:0006821320.036
regulation of organelle organizationGO:00330432890.036
amine metabolic processGO:0009308450.035
cellular response to organonitrogen compoundGO:00714171450.035
cellular amine metabolic processGO:0044106440.034
regulation of response to drugGO:200102320.034
organic anion transportGO:00157111370.034
regulation of cellular catabolic processGO:00313292420.033
cell adhesionGO:00071553290.033
microtubule based processGO:00070172360.033
regulation of ras protein signal transductionGO:00465781140.033
protein maturationGO:00516041760.032
microtubule cytoskeleton organizationGO:00002261570.032
regulation of feeding behaviorGO:006025930.031
rho protein signal transductionGO:0007266320.031
protein polymerizationGO:0051258570.031
second messenger mediated signalingGO:0019932730.031
lipid biosynthetic processGO:00086101790.031
lipid modificationGO:0030258650.030
negative regulation of molecular functionGO:00440922580.030
regulation of anatomical structure sizeGO:00900661780.030
male gamete generationGO:00482322850.030
regulation of ras gtpase activityGO:0032318880.029
regulation of nucleotide catabolic processGO:00308111220.029
positive regulation of gtp catabolic processGO:0033126850.029
regulation of cell projection organizationGO:00313442060.029
cellular homeostasisGO:00197252400.029
positive regulation of nucleoside metabolic processGO:0045979910.029
response to amino acidGO:0043200370.028
Mouse
negative regulation of phosphorylationGO:00423261660.028
regulation of peptidyl tyrosine phosphorylationGO:0050730930.028
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.028
cellular chemical homeostasisGO:00550822150.028
establishment or maintenance of cytoskeleton polarityGO:003095220.028
sodium ion exportGO:007143620.027
membrane organizationGO:00610242450.027
spermatogenesisGO:00072832840.027
dephosphorylationGO:00163111290.027
response to organonitrogen compoundGO:00102432460.027
Mouse
carboxylic acid transportGO:00469421000.026
monocarboxylic acid metabolic processGO:00327871910.026
Mouse
regulation of mapk cascadeGO:00434082480.025
regulation of metal ion transportGO:00109591060.025
single fertilizationGO:0007338820.025
regulation of cellular component sizeGO:00325351210.025
negative regulation of cellular amine metabolic processGO:003323910.025
vesicle organizationGO:0016050600.025
myelinationGO:0042552740.024
organic hydroxy compound transportGO:0015850930.024
placenta developmentGO:00018901400.024
neuron neuron synaptic transmissionGO:0007270690.024
mitotic cell cycleGO:00002781950.023
intracellular protein transportGO:00068862040.023
regulation of synaptic plasticityGO:0048167870.023
locomotory behaviorGO:00076261950.023
negative regulation of intracellular signal transductionGO:19025321670.023
positive regulation of hydrolase activityGO:00513451480.023
oxidation reduction processGO:00551143420.023
actin cytoskeleton organizationGO:00300362200.023
monosaccharide transportGO:0015749580.023
Mouse
engulfment of apoptotic cellGO:004365230.023
exocytosisGO:00068871210.023
cellular ion homeostasisGO:00068731650.022
regulation of cytoskeleton organizationGO:00514931220.022
regulation of cellular response to stressGO:00801351590.022
regulation of hormone levelsGO:00108172110.022
establishment of vesicle localizationGO:0051650810.022
regulation of circadian sleep wake cycleGO:004274930.022
dna metabolic processGO:00062593030.022
negative regulation of cellular component organizationGO:00511291940.022
positive regulation of nucleotide metabolic processGO:00459811140.022
negative regulation of cellular amino acid metabolic processGO:004576300.021
circulatory system processGO:00030131970.021
glycolipid biosynthetic processGO:0009247130.021
cell substrate adhesionGO:00315891300.021
single organismal cell cell adhesionGO:00163371310.021
endomembrane system organizationGO:00102561470.021
protein processingGO:00164851630.021
vitamin transmembrane transportGO:003546140.021
cellular potassium ion transportGO:0071804430.021
regulation of nucleotide metabolic processGO:00061401690.021
peptidyl amino acid modificationGO:00181933360.021
mitochondrion organizationGO:00070051340.021
multicellular organismal homeostasisGO:00488711640.020
positive regulation of gtpase activityGO:0043547850.020
positive regulation of cellular catabolic processGO:00313311480.020
cation homeostasisGO:00550802120.020
regulation of endocytosisGO:0030100690.020
striated muscle tissue developmentGO:00147062930.020
organelle localizationGO:00516401790.020
hydrogen ion transmembrane transportGO:1902600250.020
regulation of protein localizationGO:00328802310.020
chemotaxisGO:00069352470.020
mesodermal cell migrationGO:000807840.020
axonogenesisGO:00074092740.019
cell type specific apoptotic processGO:00972852680.019
response to peptide hormoneGO:00434341270.019
regulation of cell migrationGO:00303342190.019
response to organic cyclic compoundGO:00140701980.019
calcium ion transportGO:00068161590.019
positive regulation of nucleotide catabolic processGO:0030813880.019
regulation of protein depolymerizationGO:1901879260.019
anatomical structure homeostasisGO:00602491450.019
regulation of ion transmembrane transportGO:00347651190.019
oocyte constructionGO:000730820.019
mitotic cytokinesisGO:000028140.019
erk1 and erk2 cascadeGO:0070371770.018
actin filament organizationGO:00070151130.018
intracellular mrna localizationGO:000829840.018
angiogenesisGO:00015252010.018
receptor mediated endocytosisGO:0006898510.018
rhodopsin mediated signaling pathwayGO:001605640.018
establishment of synaptic vesicle localizationGO:0097480570.018
inflammatory responseGO:00069542440.018
negative regulation of male mating behaviorGO:190243610.018
sensory organ morphogenesisGO:00905962420.018
positive regulation of cell deathGO:00109422240.018
mitochondrion transport along microtubuleGO:004749730.018
nucleoside monophosphate metabolic processGO:0009123850.018
regulation of body fluid levelsGO:00508781620.018
digestive system developmentGO:00551232000.017
glycoprotein metabolic processGO:00091001160.017
carbohydrate derivative biosynthetic processGO:19011371830.017
maternal determination of anterior posterior axis embryoGO:000835820.017
single organism cell adhesionGO:00986021560.017
actin filament polymerizationGO:0030041440.017
actin filament based movementGO:0030048230.017
embryonic organ morphogenesisGO:00485622760.017
cellular response to histamineGO:007142010.017
rac protein signal transductionGO:0016601130.017
regulation of cell motilityGO:20001452360.017
regulation of erk1 and erk2 cascadeGO:0070372710.017
regulation of protein complex assemblyGO:0043254830.017
sulfur compound metabolic processGO:00067901000.017
calcium ion homeostasisGO:00550741270.017
positive regulation of purine nucleotide catabolic processGO:0033123880.017
divalent metal ion transportGO:00708381720.017
carboxylic acid biosynthetic processGO:0046394860.016
Mouse
cellular response to acid chemicalGO:0071229680.016
protein catabolic processGO:00301632210.016
peptidyl tyrosine modificationGO:00182121450.016
negative regulation of cellular protein metabolic processGO:00322692470.016
proteolysis involved in cellular protein catabolic processGO:00516031470.016
protein localization to organelleGO:00333651850.016
molting cycleGO:0042303900.016
regulation of rho protein signal transductionGO:0035023710.016
oocyte axis specificationGO:000730920.016
cellular response to growth factor stimulusGO:00713631970.016
homeostasis of number of cellsGO:00488722100.016
regulation of kinase activityGO:00435492490.016
hexose transportGO:0008645560.016
Mouse
regulation of actin filament polymerizationGO:0030833380.016
negative regulation of hydrolase activityGO:0051346710.016
potassium ion transmembrane transportGO:0071805430.016
regulation of cellular component biogenesisGO:00440871810.016
positive regulation of protein phosphorylationGO:00019342420.015
adult locomotory behaviorGO:0008344910.015
establishment of organelle localizationGO:00516561220.015
positive regulation of protein modification processGO:00314012990.015
regulation of ral gtpase activityGO:003231540.015
cell junction maintenanceGO:003433140.015
organonitrogen compound biosynthetic processGO:19015661920.015
Mouse
monocarboxylic acid transportGO:0015718440.015
regulation of establishment of protein localizationGO:00702011810.015
cellular macromolecule catabolic processGO:00442652060.015
actin polymerization or depolymerizationGO:0008154540.015
oligopeptide transmembrane transportGO:003567240.015
negative regulation of protein metabolic processGO:00512482820.015
negative regulation of proteolysisGO:0045861740.015
positive regulation of cell projection organizationGO:0031346950.015
positive regulation of apoptotic processGO:00430652170.015
regulation of transmembrane transportGO:00347621280.015
positive regulation of ras gtpase activityGO:0032320650.015
ribonucleoside monophosphate catabolic processGO:0009158570.014
metal ion homeostasisGO:00550651890.014
neuron apoptotic processGO:00514021420.014
oocyte anterior posterior axis specificationGO:000731420.014
multicellular organismal response to stressGO:0033555620.014
pole plasm assemblyGO:000731520.014
skeletal muscle organ developmentGO:00605381630.014
cognitionGO:00508901490.014
glycerolipid metabolic processGO:00464861220.014
negative regulation of cell proliferationGO:00082852960.014
fertilizationGO:00095661270.014
organophosphate biosynthetic processGO:00904071220.014
cellular metal ion homeostasisGO:00068751510.014
cell growthGO:00160491300.014
regulation of t cell activationGO:00508631700.014
regulation of cell activationGO:00508652890.014
cellular amino acid biosynthetic processGO:0008652220.014
Mouse
synaptic transmission glycinergicGO:006001220.014
positive regulation of necrotic cell deathGO:001094010.014
regulation of vesicle mediated transportGO:00606271390.014
blood vessel morphogenesisGO:00485142850.014
purine ribonucleoside monophosphate metabolic processGO:0009167800.014
developmental cell growthGO:0048588840.014
microtubule based transportGO:0010970500.014
cellular protein catabolic processGO:00442571550.014
skeletal system developmentGO:00015013560.014
response to inorganic substanceGO:0010035960.014
developmental growth involved in morphogenesisGO:00605601380.014
multi multicellular organism processGO:00447061090.014
muscle cell developmentGO:00550011330.014
atp metabolic processGO:0046034750.014
ear developmentGO:00435832000.014
midgut developmentGO:000749440.013
wound healingGO:00420601570.013
muscle tissue developmentGO:00605373080.013
cellular response to amino acid stimulusGO:0071230290.013
small molecule biosynthetic processGO:00442831320.013
Mouse
muscle cell differentiationGO:00426922610.013
neuron deathGO:00709971540.013
response to peptideGO:19016521360.013
regulation of sodium ion transportGO:0002028290.013
regulation of chloride transportGO:200122520.013
mitochondrion distributionGO:004831140.013
positive regulation of programmed cell deathGO:00430682180.013
striated muscle cell developmentGO:00550021250.013
negative regulation of protein modification processGO:00314001630.013
mitotic cell cycle processGO:19030471590.013
microtubule polymerization or depolymerizationGO:0031109260.013
sensory perception of touchGO:005097520.013
adult behaviorGO:00305341350.013
Mouse
muscle contractionGO:00069361010.013
establishment or maintenance of cell polarityGO:0007163860.013
neuron projection extensionGO:1990138640.013
modification dependent protein catabolic processGO:00199411330.013
cellular response to cytokine stimulusGO:00713451890.013
clathrin coat assemblyGO:004826820.013
positive regulation of cell migrationGO:00303351090.013
potassium ion transportGO:0006813520.013
sympathetic neuron projection guidanceGO:009749140.013
learningGO:0007612980.013
regulation of rho gtpase activityGO:0032319580.013
axon ensheathmentGO:0008366760.013
glycerophospholipid metabolic processGO:0006650710.013
stem cell developmentGO:00488642190.013
establishment of protein localization to organelleGO:00725941180.013
regulation of proteolysisGO:00301621640.012
response to acid chemicalGO:00011011110.012
Mouse
calcium mediated signaling using intracellular calcium sourceGO:003558430.012
establishment of mitochondrion localizationGO:005165440.012
positive regulation of phospholipase activityGO:001051830.012
membrane lipid metabolic processGO:0006643530.012
membrane lipid biosynthetic processGO:0046467320.012
negative regulation of organelle organizationGO:0010639900.012
eye photoreceptor cell differentiationGO:0001754410.012
cytoskeleton dependent intracellular transportGO:0030705500.012
cellular response to ammonium ionGO:007124220.012
carbohydrate metabolic processGO:00059752300.012
cellular response to peptideGO:1901653920.012
ventral trunk neural crest cell migrationGO:003648640.012
milk ejectionGO:006015610.012
cellular response to hormone stimulusGO:00328701500.012
negative regulation of protein processingGO:0010955790.012
negative regulation of phagocytosisGO:005076540.012
glycerolipid biosynthetic processGO:0045017500.012
immune response regulating signaling pathwayGO:00027641250.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
regulation of circadian sleep wake cycle sleepGO:004518730.012
ensheathment of neuronsGO:0007272760.012
regulation of angiogenesisGO:0045765810.012
cellular response to organic cyclic compoundGO:0071407870.012
sympathetic neuron projection extensionGO:009749040.012
blood circulationGO:00080151950.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
peptidyl tyrosine phosphorylationGO:00181081430.012
apoptotic signaling pathwayGO:00971903060.012
cofactor metabolic processGO:0051186800.012
myotube differentiationGO:00149021050.012
protein modification by small protein conjugation or removalGO:00706472070.012
sensory perception of light stimulusGO:0050953540.011
regulation of protein kinase activityGO:00458592320.011
tissue homeostasisGO:00018941150.011
sa node cell action potentialGO:008601540.011
divalent inorganic cation homeostasisGO:00725071380.011
canonical wnt signaling pathwayGO:00600701300.011
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.011
calcium ion dependent exocytosisGO:0017156350.011
response to histamineGO:003477610.011
regulation of phospholipid biosynthetic processGO:007107130.011
regulation of actin filament lengthGO:0030832450.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
sodium ion importGO:009736910.011
formation of organ boundaryGO:001016010.011
cellularizationGO:000734910.011
response to radiationGO:00093141650.011
Mouse
phospholipid metabolic processGO:0006644870.011
immune effector processGO:00022523210.011
cytokine productionGO:00018163190.011
ral protein signal transductionGO:003248420.011
cellular response to peptide hormone stimulusGO:0071375920.011
regulation of n methyl d aspartate selective glutamate receptor activityGO:2000310100.011
negative regulation of immune system processGO:00026832090.011
regulation of neuron deathGO:19012141340.011
macromolecule glycosylationGO:0043413550.011
response to drugGO:0042493750.011
Mouse
protein localization to plasma membraneGO:0072659570.011
glycosylationGO:0070085620.011
developmental maturationGO:00217001930.011
regulation of secretionGO:00510462740.011
regulation of neuron differentiationGO:00456642810.011
sodium ion export from cellGO:003637610.011
oligosaccharide biosynthetic processGO:000931270.011
response to temperature stimulusGO:0009266550.011
sensory perception of mechanical stimulusGO:00509541070.011
Mouse
associative learningGO:0008306610.011
regulation of cell projection assemblyGO:0060491380.011
negative regulation of smooth muscle cell migrationGO:001491220.011
regulation of cell cycleGO:00517262810.011
organelle fissionGO:00482851700.011
organic hydroxy compound metabolic processGO:19016152030.011
spermatid developmentGO:00072861080.011
glycogen cell differentiation involved in embryonic placenta developmentGO:006070910.010
calcium mediated signalingGO:0019722460.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
regulation of neuron apoptotic processGO:00435231220.010
regulation of heart contractionGO:0008016770.010
synaptic vesicle localizationGO:0097479590.010
digestive tract developmentGO:00485651900.010
leukocyte chemotaxisGO:0030595690.010
regulation of protein maturationGO:1903317960.010
cell cell junction organizationGO:0045216720.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
positive regulation of viral genome replicationGO:004507020.010
response to light stimulusGO:00094161350.010
Mouse
toxin transportGO:1901998380.010
tissue remodelingGO:00487711020.010

Slc1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.043
nervous system diseaseDOID:86300.043
disease of anatomical entityDOID:700.043
brain diseaseDOID:93600.018
neurodegenerative diseaseDOID:128900.012
disease of metabolismDOID:001466700.012
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010