IMP: Integrative Multi-species Prediction

Mus musculus

17 known processes

Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

(Aliases: SLC2a9A,SLC2A9B,Glut9)

Entrez: 117591
Ensembl: ENSMUSG00000005107
UniProtKB: Q8BZR3
UniProtKB: Q3T9X0
UniProtKB: Q7TSK9
UniProtKB: Q99JJ2
UniProtKB: Q5ERC7
UniProtKB: B9EHN5

Process Predictions
Disease Predictions

Slc2a9 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
anion transport	GO:0006820	177	0.254	Mouse
inorganic anion transmembrane transport	GO:0098661	29	0.204
carnitine transmembrane transport	GO:1902603	3	0.190
progesterone metabolic process	GO:0042448	4	0.156
amino acid betaine transport	GO:0015838	3	0.127
urate transport	GO:0015747	1	0.126
immune response in mucosal associated lymphoid tissue	GO:0002386	2	0.120
organic anion transport	GO:0015711	137	0.101	Mouse
carnitine metabolic process	GO:0009437	7	0.092
hexose transport	GO:0008645	56	0.088
carboxylic acid transport	GO:0046942	100	0.085
organic hydroxy compound transport	GO:0015850	93	0.082
inorganic cation transmembrane transport	GO:0098662	207	0.080
inorganic ion transmembrane transport	GO:0098660	234	0.078
transcytosis	GO:0045056	5	0.076
glucose transport	GO:0015758	56	0.074
cellular ketone metabolic process	GO:0042180	84	0.061
amino acid betaine metabolic process	GO:0006577	7	0.058
purine containing compound metabolic process	GO:0072521	311	0.057
regulation of hormone levels	GO:0010817	211	0.054
organic hydroxy compound metabolic process	GO:1901615	203	0.053
carnitine transport	GO:0015879	3	0.052
hexose transmembrane transport	GO:0035428	7	0.052
alcohol metabolic process	GO:0006066	116	0.052
regulation of defense response	GO:0031347	233	0.051
inorganic anion transport	GO:0015698	43	0.049
histamine uptake	GO:0051615	1	0.049
cation transmembrane transport	GO:0098655	266	0.047
renal system process	GO:0003014	48	0.045
organelle localization	GO:0051640	179	0.045
response to organonitrogen compound	GO:0010243	246	0.044	Mouse
histamine transport	GO:0051608	2	0.043
monocarboxylic acid metabolic process	GO:0032787	191	0.043
modification by symbiont of host morphology or physiology	GO:0044003	4	0.043
cell killing	GO:0001906	67	0.042
cation transport	GO:0006812	399	0.041
monosaccharide transport	GO:0015749	58	0.038
defense response to other organism	GO:0098542	197	0.037
multicellular organismal homeostasis	GO:0048871	164	0.037
aromatic compound catabolic process	GO:0019439	286	0.037
negative regulation of protein metabolic process	GO:0051248	282	0.037
nucleobase containing small molecule metabolic process	GO:0055086	352	0.037
secondary alcohol metabolic process	GO:1902652	3	0.036
fat soluble vitamin metabolic process	GO:0006775	11	0.035
amine metabolic process	GO:0009308	45	0.035
protein modification by small protein conjugation or removal	GO:0070647	207	0.035
response to organic cyclic compound	GO:0014070	198	0.035
carbohydrate transport	GO:0008643	62	0.034
anatomical structure homeostasis	GO:0060249	145	0.033
maintenance of location	GO:0051235	89	0.033
vitamin metabolic process	GO:0006766	23	0.032
cellular response to external stimulus	GO:0071496	88	0.032	Mouse
sodium ion transport	GO:0006814	73	0.031
regulation of cellular amine metabolic process	GO:0033238	20	0.031
nucleoside metabolic process	GO:0009116	246	0.031
anion transmembrane transport	GO:0098656	71	0.031
eye photoreceptor cell differentiation	GO:0001754	41	0.031
disruption of cells of other organism involved in symbiotic interaction	GO:0051818	13	0.031
amino acid transport	GO:0006865	61	0.031
renal tubular secretion	GO:0097254	2	0.030
small molecule biosynthetic process	GO:0044283	132	0.030
purine nucleoside metabolic process	GO:0042278	241	0.030
membrane organization	GO:0061024	245	0.029
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.029
purine ribonucleoside metabolic process	GO:0046128	241	0.028
sequestering of calcium ion	GO:0051208	18	0.028
killing of cells of other organism	GO:0031640	13	0.028
glycosyl compound metabolic process	GO:1901657	246	0.027
nitrogen compound transport	GO:0071705	271	0.027
organic acid transport	GO:0015849	101	0.027
fat soluble vitamin biosynthetic process	GO:0042362	4	0.026
cofactor metabolic process	GO:0051186	80	0.026
regulation of cellular amino acid metabolic process	GO:0006521	5	0.026
cellular nitrogen compound catabolic process	GO:0044270	280	0.026
negative regulation of cellular protein metabolic process	GO:0032269	247	0.025
purine containing compound biosynthetic process	GO:0072522	70	0.025
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.025
nucleoside triphosphate metabolic process	GO:0009141	230	0.025
myeloid cell differentiation	GO:0030099	233	0.025
response to molecule of bacterial origin	GO:0002237	143	0.024
pigment metabolic process	GO:0042440	32	0.024
negative regulation of protein modification process	GO:0031400	163	0.024
reactive oxygen species metabolic process	GO:0072593	84	0.023
regulation of cellular ketone metabolic process	GO:0010565	66	0.023
cellular alcohol metabolic process	GO:0044107	3	0.023
cellular amine metabolic process	GO:0044106	44	0.022
transmembrane transport	GO:0055085	412	0.022
cellular response to nutrient levels	GO:0031669	64	0.021	Mouse
cellular alcohol biosynthetic process	GO:0044108	3	0.021
leukocyte mediated immunity	GO:0002443	174	0.021
hematopoietic progenitor cell differentiation	GO:0002244	143	0.021
organonitrogen compound biosynthetic process	GO:1901566	192	0.021
regulation of cell activation	GO:0050865	289	0.021
locomotory behavior	GO:0007626	195	0.021
cellular amino acid metabolic process	GO:0006520	103	0.021
defense response to bacterium	GO:0042742	119	0.020
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.020
divalent metal ion transport	GO:0070838	172	0.020
positive regulation of defense response	GO:0031349	124	0.020
urea transmembrane transport	GO:0071918	2	0.020
fluid transport	GO:0042044	14	0.020
divalent inorganic cation transport	GO:0072511	178	0.020
cellular response to lipid	GO:0071396	145	0.020
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.019
response to nutrient levels	GO:0031667	109	0.019	Mouse
response to drug	GO:0042493	75	0.019
mitochondrion organization	GO:0007005	134	0.019
small gtpase mediated signal transduction	GO:0007264	97	0.019
response to starvation	GO:0042594	65	0.019	Mouse
nuclear division	GO:0000280	158	0.018
cellular lipid metabolic process	GO:0044255	323	0.018
cytokine production	GO:0001816	319	0.018
regulation of neurotransmitter levels	GO:0001505	87	0.018
myeloid leukocyte differentiation	GO:0002573	119	0.018
innate immune response	GO:0045087	157	0.018
retina homeostasis	GO:0001895	23	0.018
actin cytoskeleton organization	GO:0030036	220	0.018
monocarboxylic acid transport	GO:0015718	44	0.018
purine ribonucleoside catabolic process	GO:0046130	205	0.018
organophosphate biosynthetic process	GO:0090407	122	0.018
organic acid biosynthetic process	GO:0016053	86	0.018
cation homeostasis	GO:0055080	212	0.018
immune effector process	GO:0002252	321	0.018
nucleotide metabolic process	GO:0009117	332	0.017
thick ascending limb development	GO:0072023	2	0.017
ascending thin limb development	GO:0072021	2	0.017
dicarboxylic acid transport	GO:0006835	29	0.017
regulation of secretion	GO:0051046	274	0.017
cell type specific apoptotic process	GO:0097285	268	0.017
response to osmotic stress	GO:0006970	21	0.017	Mouse
tissue homeostasis	GO:0001894	115	0.017
cellular response to biotic stimulus	GO:0071216	92	0.017
response to acid chemical	GO:0001101	111	0.017
reactive nitrogen species metabolic process	GO:2001057	0	0.017
cellular response to hormone stimulus	GO:0032870	150	0.017	Mouse
hydrogen ion transmembrane transport	GO:1902600	25	0.017
developmental growth involved in morphogenesis	GO:0060560	138	0.017
regulation of inflammatory response	GO:0050727	147	0.017
glucuronate metabolic process	GO:0019585	2	0.016
body fluid secretion	GO:0007589	53	0.016
detection of molecule of bacterial origin	GO:0032490	2	0.016
ribonucleoside metabolic process	GO:0009119	245	0.016
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.016
protein modification by small protein conjugation	GO:0032446	187	0.016
ribonucleotide metabolic process	GO:0009259	291	0.016
t cell activation	GO:0042110	289	0.016
cellular response to extracellular stimulus	GO:0031668	81	0.016	Mouse
neurotransmitter transport	GO:0006836	76	0.016
ribonucleotide catabolic process	GO:0009261	208	0.016
nucleotide catabolic process	GO:0009166	217	0.016
cellular response to cadmium ion	GO:0071276	3	0.016
regulation of organelle organization	GO:0033043	289	0.016
response to inorganic substance	GO:0010035	96	0.016
response to oxidative stress	GO:0006979	123	0.016
amino acid transmembrane transport	GO:0003333	37	0.016
positive regulation of protein modification process	GO:0031401	299	0.015
naphthalene containing compound metabolic process	GO:0090420	1	0.015
nucleoside catabolic process	GO:0009164	206	0.015
smad protein signal transduction	GO:0060395	21	0.015
response to extracellular stimulus	GO:0009991	127	0.015	Mouse
cellular macromolecule catabolic process	GO:0044265	206	0.015
renal sodium ion transport	GO:0003096	2	0.015
dna metabolic process	GO:0006259	303	0.015
positive regulation of cellular amine metabolic process	GO:0033240	5	0.015
oxidation reduction process	GO:0055114	342	0.015
cellular homeostasis	GO:0019725	240	0.015
peptide transport	GO:0015833	133	0.015
regulation of leukocyte mediated immunity	GO:0002703	104	0.015
nucleoside phosphate catabolic process	GO:1901292	222	0.015
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.015
monocarboxylic acid biosynthetic process	GO:0072330	61	0.015
l amino acid transport	GO:0015807	32	0.015
heterocycle catabolic process	GO:0046700	280	0.015
steroid metabolic process	GO:0008202	119	0.015
cell activation involved in immune response	GO:0002263	126	0.015
uronic acid metabolic process	GO:0006063	2	0.015
regulation of wnt signaling pathway	GO:0030111	123	0.015
development of primary sexual characteristics	GO:0045137	143	0.014
regulation of interleukin 8 production	GO:0032677	3	0.014
cellular response to molecule of bacterial origin	GO:0071219	83	0.014
renal system development	GO:0072001	225	0.014
vitamin d biosynthetic process	GO:0042368	3	0.014
ras protein signal transduction	GO:0007265	77	0.014
cell adhesion	GO:0007155	329	0.014
carbohydrate homeostasis	GO:0033500	128	0.014
metal ion homeostasis	GO:0055065	189	0.014
nucleoside phosphate metabolic process	GO:0006753	338	0.014
response to growth factor	GO:0070848	198	0.014
protein ubiquitination	GO:0016567	171	0.014
metanephric thick ascending limb development	GO:0072233	2	0.014
calcium ion transport	GO:0006816	159	0.014
divalent inorganic cation homeostasis	GO:0072507	138	0.014
regulation of cytokine production	GO:0001817	266	0.014
engulfment of apoptotic cell	GO:0043652	3	0.014
interspecies interaction between organisms	GO:0044419	83	0.014
purine nucleotide metabolic process	GO:0006163	302	0.014
potassium ion homeostasis	GO:0055075	4	0.014
ion transmembrane transport	GO:0034220	361	0.013
regulation of hydrolase activity	GO:0051336	246	0.013
cellular response to lipopolysaccharide	GO:0071222	77	0.013
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.013
organelle assembly	GO:0070925	177	0.013
carbohydrate derivative catabolic process	GO:1901136	231	0.013
apoptotic signaling pathway	GO:0097190	306	0.013
water transport	GO:0006833	12	0.013
positive regulation of secretion	GO:0051047	130	0.013
purine ribonucleotide metabolic process	GO:0009150	290	0.013
amide transport	GO:0042886	138	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.013
monoamine transport	GO:0015844	33	0.013
glycosyl compound catabolic process	GO:1901658	206	0.013
nephron development	GO:0072006	109	0.013
leukocyte differentiation	GO:0002521	342	0.013
cellular ion homeostasis	GO:0006873	165	0.013
urogenital system development	GO:0001655	261	0.013
disruption of cells of other organism	GO:0044364	13	0.013
regulation of homeostatic process	GO:0032844	182	0.013
cell substrate adhesion	GO:0031589	130	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.013
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.013
development of primary female sexual characteristics	GO:0046545	73	0.013
positive regulation of cell death	GO:0010942	224	0.013
positive regulation of response to wounding	GO:1903036	66	0.013
negative regulation of cellular component organization	GO:0051129	194	0.012
regulation of ph	GO:0006885	26	0.012
nucleoside monophosphate metabolic process	GO:0009123	85	0.012
macromolecule catabolic process	GO:0009057	281	0.012
endomembrane system organization	GO:0010256	147	0.012
purine containing compound catabolic process	GO:0072523	213	0.012
naphthalene metabolic process	GO:0018931	1	0.012
inflammatory response	GO:0006954	244	0.012
lipid localization	GO:0010876	126	0.012
purine nucleoside catabolic process	GO:0006152	205	0.012
organophosphate catabolic process	GO:0046434	232	0.012
sequestering of metal ion	GO:0051238	19	0.012
ribonucleoside catabolic process	GO:0042454	206	0.012
regulation of mast cell activation	GO:0033003	21	0.012
organelle fission	GO:0048285	170	0.012
regulation of membrane potential	GO:0042391	192	0.012
cellular response to peptidoglycan	GO:0071224	4	0.012
cofactor transport	GO:0051181	4	0.012
antigen processing and presentation of exogenous antigen	GO:0019884	26	0.012
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.012
gonad development	GO:0008406	141	0.012
leukocyte mediated cytotoxicity	GO:0001909	62	0.012
cellular protein catabolic process	GO:0044257	155	0.012
sensory perception	GO:0007600	245	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012
negative regulation of immune system process	GO:0002683	209	0.012
cellular response to starvation	GO:0009267	57	0.012	Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.012
fatty acid metabolic process	GO:0006631	121	0.011
l ascorbic acid metabolic process	GO:0019852	4	0.011
urate metabolic process	GO:0046415	2	0.011
positive regulation of apoptotic process	GO:0043065	217	0.011
oxidative demethylation	GO:0070989	1	0.011
leukocyte activation involved in immune response	GO:0002366	126	0.011
cellular response to dna damage stimulus	GO:0006974	207	0.011
organonitrogen compound catabolic process	GO:1901565	264	0.011
regulation of cellular component biogenesis	GO:0044087	181	0.011
lipid biosynthetic process	GO:0008610	179	0.011
steroid biosynthetic process	GO:0006694	47	0.011
regulation of response to wounding	GO:1903034	189	0.011
small molecule catabolic process	GO:0044282	71	0.011
intrinsic apoptotic signaling pathway	GO:0097193	132	0.011
regulation of cell motility	GO:2000145	236	0.011
regulation of cellular component size	GO:0032535	121	0.011
hydrogen transport	GO:0006818	35	0.011
posttranscriptional regulation of gene expression	GO:0010608	155	0.011
cognition	GO:0050890	149	0.011
response to lipopolysaccharide	GO:0032496	128	0.011
regulation of cell killing	GO:0031341	40	0.011
regulation of blood pressure	GO:0008217	93	0.011
regulation of vesicle mediated transport	GO:0060627	139	0.011
positive regulation of hydrolase activity	GO:0051345	148	0.011
mast cell activation	GO:0045576	27	0.011
regulation of proteolysis	GO:0030162	164	0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.011
ketone catabolic process	GO:0042182	3	0.011
cellular response to inorganic substance	GO:0071241	37	0.011
cellular response to acid chemical	GO:0071229	68	0.011
negative regulation of hormone metabolic process	GO:0032351	4	0.011
excretion	GO:0007588	22	0.011
positive regulation of secretion by cell	GO:1903532	114	0.011
forebrain development	GO:0030900	302	0.011
regulation of leukocyte differentiation	GO:1902105	159	0.010
regulation of cellular catabolic process	GO:0031329	242	0.010
epidermis development	GO:0008544	187	0.010
regulation of interleukin 8 secretion	GO:2000482	2	0.010
nucleoside triphosphate catabolic process	GO:0009143	205	0.010
gland development	GO:0048732	330	0.010
metanephric nephron epithelium development	GO:0072243	19	0.010
chloride transport	GO:0006821	32	0.010
positive regulation of phospholipase activity	GO:0010518	3	0.010
male gamete generation	GO:0048232	285	0.010
bile acid and bile salt transport	GO:0015721	5	0.010
cytolysis	GO:0019835	8	0.010

Slc2a9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.034
inherited metabolic disorder	DOID:655	0.020
disease of cellular proliferation	DOID:14566	0.017
organ system cancer	DOID:0050686	0.016
cancer	DOID:162	0.016
nervous system disease	DOID:863	0.015
disease of anatomical entity	DOID:7	0.015
immune system disease	DOID:2914	0.013
hematopoietic system disease	DOID:74	0.012
connective tissue disease	DOID:65	0.012
musculoskeletal system disease	DOID:17	0.012
eye and adnexa disease	DOID:1492	0.011
sensory system disease	DOID:0050155	0.011
eye disease	DOID:5614	0.011
cardiovascular system disease	DOID:1287	0.010

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