IMP: Integrative Multi-species Prediction

Mus musculus

138 known processes

Scrib

scribbled homolog (Drosophila)

(Aliases: mKIAA0147,vartul,SCRIB1,CRIB,AI118201,KIAA0147,Crc,Scrb1)

Entrez: 105782
Ensembl: ENSMUSG00000022568
UniProtKB: Q80U72

Process Predictions
Disease Predictions

Scrib biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
dna metabolic process	GO:0006259	303	0.214
male gamete generation	GO:0048232	285	0.134
leukocyte differentiation	GO:0002521	342	0.126
spermatogenesis	GO:0007283	284	0.126
cellular response to dna damage stimulus	GO:0006974	207	0.123
regulation of organelle organization	GO:0033043	289	0.114	Worm
macromolecule catabolic process	GO:0009057	281	0.108
negative regulation of cell proliferation	GO:0008285	296	0.106
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.099
cellular ketone metabolic process	GO:0042180	84	0.099
regulation of cellular ketone metabolic process	GO:0010565	66	0.089
purine nucleoside catabolic process	GO:0006152	205	0.088	Human
negative regulation of cellular protein metabolic process	GO:0032269	247	0.085
cellular amino acid metabolic process	GO:0006520	103	0.082
regulation of protein kinase activity	GO:0045859	232	0.078
regulation of cellular catabolic process	GO:0031329	242	0.078	Human
purine containing compound metabolic process	GO:0072521	311	0.074	Human
covalent chromatin modification	GO:0016569	163	0.073
apoptotic signaling pathway	GO:0097190	306	0.071
negative regulation of molecular function	GO:0044092	258	0.070
carbohydrate derivative catabolic process	GO:1901136	231	0.067	Human
cellular amine metabolic process	GO:0044106	44	0.066
glycosyl compound metabolic process	GO:1901657	246	0.066	Human
peptidyl amino acid modification	GO:0018193	336	0.065
regulation of kinase activity	GO:0043549	249	0.065
chromatin organization	GO:0006325	206	0.064
multi multicellular organism process	GO:0044706	109	0.058
cellular nitrogen compound catabolic process	GO:0044270	280	0.057	Human
positive regulation of protein modification process	GO:0031401	299	0.056
oocyte construction	GO:0007308	2	0.056
segmentation	GO:0035282	93	0.055
regulation of purine nucleotide metabolic process	GO:1900542	169	0.054	Human
protein localization to nucleus	GO:0034504	121	0.054
protein ubiquitination	GO:0016567	171	0.054
regulation of cell cycle checkpoint	GO:1901976	9	0.053
nucleobase containing small molecule metabolic process	GO:0055086	352	0.053	Human
ribose phosphate metabolic process	GO:0019693	291	0.052	Human
stem cell differentiation	GO:0048863	268	0.052
cytokine production	GO:0001816	319	0.051
mitotic cell cycle	GO:0000278	195	0.051	Human Zebrafish
heterocycle catabolic process	GO:0046700	280	0.050	Human
protein modification by small protein conjugation or removal	GO:0070647	207	0.049
actin cytoskeleton organization	GO:0030036	220	0.049
amine metabolic process	GO:0009308	45	0.048
homeostasis of number of cells	GO:0048872	210	0.048
regulation of transferase activity	GO:0051338	263	0.046
rhythmic process	GO:0048511	174	0.046
metal ion homeostasis	GO:0055065	189	0.045
intracellular protein transport	GO:0006886	204	0.045	Mouse
oocyte axis specification	GO:0007309	2	0.045
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.044	Human
stem cell development	GO:0048864	219	0.044
lateral inhibition	GO:0046331	1	0.044
sensory perception	GO:0007600	245	0.043
microtubule based process	GO:0007017	236	0.043	Zebrafish
response to organonitrogen compound	GO:0010243	246	0.043
positive regulation of cellular catabolic process	GO:0031331	148	0.043	Human
regulation of cell cycle	GO:0051726	281	0.042	Human
positive regulation of organelle organization	GO:0010638	128	0.041
immune effector process	GO:0002252	321	0.041
protein catabolic process	GO:0030163	221	0.041
regulation of chromosome organization	GO:0033044	83	0.040
posttranscriptional regulation of gene expression	GO:0010608	155	0.040
purine ribonucleotide metabolic process	GO:0009150	290	0.039	Human
protein modification by small protein conjugation	GO:0032446	187	0.039
response to acid chemical	GO:0001101	111	0.038
cell adhesion	GO:0007155	329	0.038	Human Worm
placenta development	GO:0001890	140	0.038
cell type specific apoptotic process	GO:0097285	268	0.038
nucleoside metabolic process	GO:0009116	246	0.038	Human
regulation of protein serine threonine kinase activity	GO:0071900	157	0.037
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.036
histone deubiquitination	GO:0016578	2	0.036
purine nucleotide metabolic process	GO:0006163	302	0.036	Human
aromatic compound catabolic process	GO:0019439	286	0.036	Human
regulation of protein localization	GO:0032880	231	0.036
respiratory tube development	GO:0030323	167	0.036
positive regulation of cellular amine metabolic process	GO:0033240	5	0.036
negative regulation of protein metabolic process	GO:0051248	282	0.035
ribonucleotide metabolic process	GO:0009259	291	0.035	Human
protein localization to organelle	GO:0033365	185	0.035
regulation of hydrolase activity	GO:0051336	246	0.035	Human
reactive oxygen species metabolic process	GO:0072593	84	0.035
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.035
proteasomal protein catabolic process	GO:0010498	98	0.035
regulation of multi organism process	GO:0043900	111	0.035
cellular chemical homeostasis	GO:0055082	215	0.035
developmental maturation	GO:0021700	193	0.034
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.034
germ cell development	GO:0007281	185	0.034
camera type eye development	GO:0043010	266	0.033
organonitrogen compound biosynthetic process	GO:1901566	192	0.033
b cell activation	GO:0042113	161	0.033
embryonic placenta development	GO:0001892	98	0.033
positive regulation of protein kinase activity	GO:0045860	144	0.033
negative regulation of immune system process	GO:0002683	209	0.033
negative regulation of proteolysis	GO:0045861	74	0.033
cellular macromolecule catabolic process	GO:0044265	206	0.032
ribonucleotide catabolic process	GO:0009261	208	0.032	Human
regulation of cellular response to stress	GO:0080135	159	0.032
lymphocyte differentiation	GO:0030098	242	0.032
intrinsic apoptotic signaling pathway	GO:0097193	132	0.032
forebrain development	GO:0030900	302	0.032
response to oxidative stress	GO:0006979	123	0.032
pole plasm assembly	GO:0007315	2	0.032
histone acetylation	GO:0016573	41	0.032
antimicrobial peptide production	GO:0002775	2	0.032
protein targeting	GO:0006605	143	0.032	Mouse
calcium ion homeostasis	GO:0055074	127	0.031
positive regulation of transferase activity	GO:0051347	167	0.030
cellular response to organonitrogen compound	GO:0071417	145	0.030
protein processing	GO:0016485	163	0.030
regulation of cellular amine metabolic process	GO:0033238	20	0.030
purine ribonucleoside catabolic process	GO:0046130	205	0.030	Human
regulation of establishment of protein localization	GO:0070201	181	0.030
rna interference	GO:0016246	2	0.030
stem cell fate specification	GO:0048866	3	0.030
regulation of cellular amino acid metabolic process	GO:0006521	5	0.030
chemotaxis	GO:0006935	247	0.030
response to radiation	GO:0009314	165	0.029
multicellular organism growth	GO:0035264	161	0.029
cellular response to lipid	GO:0071396	145	0.028
cellular protein catabolic process	GO:0044257	155	0.028
regionalization	GO:0003002	337	0.028
connective tissue development	GO:0061448	179	0.028
macromolecule methylation	GO:0043414	120	0.028
positive regulation of nervous system development	GO:0051962	221	0.028
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.028	Human
modification dependent protein catabolic process	GO:0019941	133	0.028
regulation of cell cycle process	GO:0010564	160	0.028
negative regulation of protein processing	GO:0010955	79	0.028
response to molecule of bacterial origin	GO:0002237	143	0.028
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.027
purine nucleoside metabolic process	GO:0042278	241	0.027	Human
single organism nuclear import	GO:1902593	95	0.027
establishment of protein localization to organelle	GO:0072594	118	0.027
regulation of histone methylation	GO:0031060	30	0.027
cell growth	GO:0016049	130	0.027
nuclear import	GO:0051170	95	0.027
modification dependent macromolecule catabolic process	GO:0043632	133	0.026
gland development	GO:0048732	330	0.026
protein acylation	GO:0043543	64	0.026
transmembrane transport	GO:0055085	412	0.026
tumor necrosis factor superfamily cytokine production	GO:0071706	51	0.026
regulation of cell activation	GO:0050865	289	0.026
negative regulation of protein maturation	GO:1903318	79	0.026
regulation of nucleotide catabolic process	GO:0030811	122	0.026	Human
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.026
organelle fission	GO:0048285	170	0.025
t cell activation	GO:0042110	289	0.025
regulation of leukocyte differentiation	GO:1902105	159	0.025
positive regulation of nucleotide metabolic process	GO:0045981	114	0.025	Human
protein maturation	GO:0051604	176	0.025
cellular ion homeostasis	GO:0006873	165	0.025
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway	GO:0043162	3	0.025
nucleotide catabolic process	GO:0009166	217	0.025	Human
regulation of proteolysis	GO:0030162	164	0.025
positive regulation of dna templated transcription elongation	GO:0032786	2	0.025
skeletal system development	GO:0001501	356	0.025
regulation of apoptotic signaling pathway	GO:2001233	197	0.025
cation homeostasis	GO:0055080	212	0.025
regulation of homeostatic process	GO:0032844	182	0.025
lung development	GO:0030324	164	0.025
response to light stimulus	GO:0009416	135	0.025
autophagy	GO:0006914	45	0.024
telencephalon development	GO:0021537	186	0.024
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.024	Human
response to peptide hormone	GO:0043434	127	0.024
organic cyclic compound catabolic process	GO:1901361	295	0.024	Human
methylation	GO:0032259	134	0.024
positive regulation of kinase activity	GO:0033674	155	0.024
histone lysine methylation	GO:0034968	50	0.024
nuclear transport	GO:0051169	139	0.024
regulation of protein transport	GO:0051223	163	0.024
myeloid leukocyte differentiation	GO:0002573	119	0.024
protein oligomerization	GO:0051259	67	0.024
g protein coupled receptor signaling pathway	GO:0007186	243	0.024
neuron projection guidance	GO:0097485	141	0.024
blood vessel morphogenesis	GO:0048514	285	0.024
cell maturation	GO:0048469	127	0.024
cellular homeostasis	GO:0019725	240	0.023
positive regulation of ras gtpase activity	GO:0032320	65	0.023	Human
female gamete generation	GO:0007292	74	0.023	Worm
cellular lipid metabolic process	GO:0044255	323	0.023
muscle tissue development	GO:0060537	308	0.023
protein methylation	GO:0006479	81	0.023
signal transduction by p53 class mediator	GO:0072331	51	0.023
dna repair	GO:0006281	107	0.023
response to organic cyclic compound	GO:0014070	198	0.023
actin filament organization	GO:0007015	113	0.023
microtubule cytoskeleton organization	GO:0000226	157	0.023	Zebrafish
nucleoside phosphate metabolic process	GO:0006753	338	0.023	Human
positive regulation of protein phosphorylation	GO:0001934	242	0.023
histone methylation	GO:0016571	71	0.022
gtp catabolic process	GO:0006184	143	0.022	Human
cation transport	GO:0006812	399	0.022
regulation of chromatin organization	GO:1902275	57	0.022
regulation of anatomical structure size	GO:0090066	178	0.022
regulation of cytoskeleton organization	GO:0051493	122	0.022	Worm
nucleotide metabolic process	GO:0009117	332	0.022	Human
regulation of histone h3 k4 methylation	GO:0051569	12	0.022
maintenance of location	GO:0051235	89	0.022
positive regulation of hydrolase activity	GO:0051345	148	0.022	Human
kidney development	GO:0001822	213	0.021
urogenital system development	GO:0001655	261	0.021
regulation of cellular component biogenesis	GO:0044087	181	0.021
protein import into nucleus	GO:0006606	95	0.021
positive regulation of programmed cell death	GO:0043068	218	0.021	Human
tumor necrosis factor production	GO:0032640	50	0.021
positive regulation of intracellular transport	GO:0032388	70	0.021
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.021
regulation of protein targeting	GO:1903533	61	0.021
cellular metal ion homeostasis	GO:0006875	151	0.021
positive regulation of cell development	GO:0010720	237	0.021
regulation of ras protein signal transduction	GO:0046578	114	0.021	Human
mapk cascade	GO:0000165	281	0.021
transmission of nerve impulse	GO:0019226	76	0.020
positive regulation of map kinase activity	GO:0043406	84	0.020
glycosyl compound catabolic process	GO:1901658	206	0.020	Human
action potential	GO:0001508	78	0.020
regulation of antimicrobial humoral response	GO:0002759	3	0.020
cellular amide metabolic process	GO:0043603	58	0.020
regulation of protein import into nucleus	GO:0042306	52	0.020
response to growth factor	GO:0070848	198	0.019
protein autophosphorylation	GO:0046777	61	0.019
multicellular organismal signaling	GO:0035637	91	0.019
regulation of membrane potential	GO:0042391	192	0.019
regulation of lymphocyte activation	GO:0051249	240	0.019
nucleoside triphosphate metabolic process	GO:0009141	230	0.019	Human
ribonucleoside catabolic process	GO:0042454	206	0.019	Human
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.019	Human
regulation of endopeptidase activity	GO:0052548	89	0.019
regulation of nucleoside metabolic process	GO:0009118	130	0.019	Human
intracellular receptor signaling pathway	GO:0030522	74	0.019
response to reactive oxygen species	GO:0000302	56	0.019
peptidyl lysine modification	GO:0018205	77	0.019
regulation of cellular protein catabolic process	GO:1903362	61	0.019
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.019
positive regulation of mapk cascade	GO:0043410	170	0.019
epithelial tube morphogenesis	GO:0060562	303	0.018
negative regulation of intracellular signal transduction	GO:1902532	167	0.018
endomembrane system organization	GO:0010256	147	0.018
regulation of chromatin modification	GO:1903308	57	0.018
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.018	Human
sequestering of calcium ion	GO:0051208	18	0.018
purine containing compound catabolic process	GO:0072523	213	0.018	Human
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.018	Human
regulation of cell adhesion	GO:0030155	154	0.018
organophosphate catabolic process	GO:0046434	232	0.018	Human
leukocyte activation involved in immune response	GO:0002366	126	0.018
gonad development	GO:0008406	141	0.018	Worm
phospholipid metabolic process	GO:0006644	87	0.018
cytoplasmic transport	GO:0016482	234	0.018
lens development in camera type eye	GO:0002088	62	0.018
negative regulation of organelle organization	GO:0010639	90	0.018
regulation of cytokine production	GO:0001817	266	0.017
regulation of cell motility	GO:2000145	236	0.017
organelle assembly	GO:0070925	177	0.017
regulation of tumor necrosis factor production	GO:0032680	49	0.017
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.017
locomotory behavior	GO:0007626	195	0.017
innate immune response	GO:0045087	157	0.017
meiosis i	GO:0007127	60	0.017
response to oxygen levels	GO:0070482	62	0.017
positive regulation of nucleotide catabolic process	GO:0030813	88	0.017	Human
regulation of neuron death	GO:1901214	134	0.017
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.016
oocyte anterior posterior axis specification	GO:0007314	2	0.016
regulation of hormone levels	GO:0010817	211	0.016
regulation of antimicrobial peptide production	GO:0002784	1	0.016
nitrogen compound transport	GO:0071705	271	0.016
cell fate commitment	GO:0045165	210	0.016
neuron death	GO:0070997	154	0.016
carbohydrate derivative biosynthetic process	GO:1901137	183	0.016
regulation of leukocyte mediated immunity	GO:0002703	104	0.016
adult behavior	GO:0030534	135	0.016
nucleoside catabolic process	GO:0009164	206	0.016	Human
skeletal system morphogenesis	GO:0048705	203	0.016
purine ribonucleoside metabolic process	GO:0046128	241	0.016	Human
fat cell differentiation	GO:0045444	160	0.016
zygotic determination of anterior posterior axis embryo	GO:0007354	3	0.016
heart morphogenesis	GO:0003007	178	0.016
regulation of neuron projection development	GO:0010975	169	0.016
regulation of protein catabolic process	GO:0042176	108	0.016
cell recognition	GO:0008037	83	0.016
membrane organization	GO:0061024	245	0.016
cellular calcium ion homeostasis	GO:0006874	119	0.016
b cell differentiation	GO:0030183	78	0.016
mrna metabolic process	GO:0016071	84	0.016
ion transmembrane transport	GO:0034220	361	0.016
negative regulation of protein modification process	GO:0031400	163	0.016
regulation of production of molecular mediator of immune response	GO:0002700	65	0.016
divalent inorganic cation homeostasis	GO:0072507	138	0.016
protein alkylation	GO:0008213	81	0.016
cognition	GO:0050890	149	0.015
lymphocyte mediated immunity	GO:0002449	139	0.015
intracellular mrna localization	GO:0008298	4	0.015
stem cell proliferation	GO:0072089	117	0.015
pallium development	GO:0021543	120	0.015
regulation of nucleotide metabolic process	GO:0006140	169	0.015	Human
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.015
mitotic cell cycle process	GO:1903047	159	0.015	Zebrafish
response to extracellular stimulus	GO:0009991	127	0.015
regulation of protein processing	GO:0070613	96	0.015
developmental growth involved in morphogenesis	GO:0060560	138	0.015
guanosine containing compound metabolic process	GO:1901068	144	0.015	Human
hematopoietic progenitor cell differentiation	GO:0002244	143	0.015
neural precursor cell proliferation	GO:0061351	121	0.015
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.015
spermatid differentiation	GO:0048515	115	0.015
myeloid cell differentiation	GO:0030099	233	0.015
development of primary sexual characteristics	GO:0045137	143	0.015	Worm
ubiquitin dependent protein catabolic process	GO:0006511	129	0.015
tissue homeostasis	GO:0001894	115	0.015
antimicrobial peptide biosynthetic process	GO:0002777	2	0.015
lipid biosynthetic process	GO:0008610	179	0.015
muscle cell differentiation	GO:0042692	261	0.015
internal protein amino acid acetylation	GO:0006475	42	0.015
organ growth	GO:0035265	117	0.015
response to peptide	GO:1901652	136	0.015
guanosine containing compound catabolic process	GO:1901069	144	0.015	Human
organelle localization	GO:0051640	179	0.015
regulation of antimicrobial peptide biosynthetic process	GO:0002805	1	0.015
regulation of neuron apoptotic process	GO:0043523	122	0.015
demethylation	GO:0070988	23	0.015
regulation of lipid metabolic process	GO:0019216	118	0.015
response to lipopolysaccharide	GO:0032496	128	0.015
respiratory system development	GO:0060541	190	0.014
spermatid development	GO:0007286	108	0.014
negative regulation of cell development	GO:0010721	169	0.014
regulation of neuron differentiation	GO:0045664	281	0.014
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.014
nucleoside monophosphate metabolic process	GO:0009123	85	0.014
small gtpase mediated signal transduction	GO:0007264	97	0.014
cell activation involved in immune response	GO:0002263	126	0.014
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.014
organophosphate biosynthetic process	GO:0090407	122	0.014
regulation of response to biotic stimulus	GO:0002831	38	0.014
regulation of secretion by cell	GO:1903530	249	0.014
receptor mediated endocytosis	GO:0006898	51	0.014
response to oxygen radical	GO:0000305	16	0.014
response to nutrient levels	GO:0031667	109	0.014
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.014
regulation of binding	GO:0051098	111	0.014
regulation of defense response	GO:0031347	233	0.014
protein import	GO:0017038	101	0.014
myeloid cell homeostasis	GO:0002262	114	0.014
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.014
divalent metal ion transport	GO:0070838	172	0.014
immunoglobulin mediated immune response	GO:0016064	69	0.014
sequestering of metal ion	GO:0051238	19	0.014
regulation of lymphocyte mediated immunity	GO:0002706	84	0.014
rna processing	GO:0006396	105	0.014
nucleocytoplasmic transport	GO:0006913	139	0.014
negative regulation of cellular component organization	GO:0051129	194	0.014
cell division	GO:0051301	120	0.014
monosaccharide metabolic process	GO:0005996	106	0.014
regulation of autophagy	GO:0010506	30	0.014
response to inorganic substance	GO:0010035	96	0.014
male meiosis	GO:0007140	37	0.014
divalent inorganic cation transport	GO:0072511	178	0.014
rab protein signal transduction	GO:0032482	1	0.014
regulation of system process	GO:0044057	200	0.014
erbb signaling pathway	GO:0038127	32	0.014
amide transport	GO:0042886	138	0.013
cell substrate adhesion	GO:0031589	130	0.013
oocyte differentiation	GO:0009994	35	0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.013
glucose homeostasis	GO:0042593	128	0.013
cellular response to peptide	GO:1901653	92	0.013
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.013
regulation of nucleocytoplasmic transport	GO:0046822	73	0.013
regulation of cell projection organization	GO:0031344	206	0.013
regulation of myeloid cell differentiation	GO:0045637	96	0.013
multicellular organismal homeostasis	GO:0048871	164	0.013
cellular response to insulin stimulus	GO:0032869	78	0.013
regulation of embryonic development	GO:0045995	71	0.013
regulation of translation	GO:0006417	71	0.013
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.013
gene silencing	GO:0016458	38	0.013
carbohydrate homeostasis	GO:0033500	128	0.013
cellular response to hormone stimulus	GO:0032870	150	0.013
mrna catabolic process	GO:0006402	22	0.013
ribonucleoside metabolic process	GO:0009119	245	0.013	Human
negative regulation of cellular amine metabolic process	GO:0033239	1	0.013
dna recombination	GO:0006310	92	0.013
peptide metabolic process	GO:0006518	46	0.013
production of molecular mediator of immune response	GO:0002440	103	0.013
oogenesis	GO:0048477	56	0.013
peptide transport	GO:0015833	133	0.013
localization within membrane	GO:0051668	4	0.013
histone modification	GO:0016570	159	0.013
dna alkylation	GO:0006305	43	0.013
learning or memory	GO:0007611	148	0.013
gastrulation	GO:0007369	116	0.013	Zebrafish
skeletal muscle organ development	GO:0060538	163	0.012
positive regulation of cell death	GO:0010942	224	0.012	Human
positive regulation of protein transport	GO:0051222	93	0.012
lymphocyte activation involved in immune response	GO:0002285	93	0.012
glycerophospholipid metabolic process	GO:0006650	71	0.012
epidermal growth factor receptor signaling pathway	GO:0007173	28	0.012
axonogenesis	GO:0007409	274	0.012
neuronal action potential	GO:0019228	54	0.012
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	50	0.012
fertilization	GO:0009566	127	0.012
meiotic cell cycle	GO:0051321	122	0.012
dna modification	GO:0006304	50	0.012
positive regulation of cytokine production	GO:0001819	174	0.012
regulation of ion transmembrane transport	GO:0034765	119	0.012
response to insulin	GO:0032868	100	0.012
regulation of protein stability	GO:0031647	52	0.012
positive regulation of intracellular protein transport	GO:0090316	42	0.012
cellular response to superoxide	GO:0071451	14	0.012
regulation of ras gtpase activity	GO:0032318	88	0.012	Human
cellular response to peptide hormone stimulus	GO:0071375	92	0.012
cellular response to growth factor stimulus	GO:0071363	197	0.012
learning	GO:0007612	98	0.012
dna dealkylation	GO:0035510	11	0.012
adult locomotory behavior	GO:0008344	91	0.012
renal system development	GO:0072001	225	0.012
regulation of lymphocyte differentiation	GO:0045619	107	0.012
endocytosis	GO:0006897	168	0.012
digestive tract development	GO:0048565	190	0.012	Zebrafish Worm
tube closure	GO:0060606	91	0.012
epithelial cell development	GO:0002064	159	0.012
hormone secretion	GO:0046879	128	0.012
response to transforming growth factor beta	GO:0071559	88	0.012
lipid homeostasis	GO:0055088	63	0.012
positive regulation of immune effector process	GO:0002699	107	0.012
regulation of epithelial cell proliferation	GO:0050678	141	0.012
ras protein signal transduction	GO:0007265	77	0.012
wnt signaling pathway	GO:0016055	188	0.012
stress activated protein kinase signaling cascade	GO:0031098	81	0.012
axon guidance	GO:0007411	141	0.011
leukocyte mediated immunity	GO:0002443	174	0.011
nuclear division	GO:0000280	158	0.011
ossification	GO:0001503	216	0.011
oxidation reduction process	GO:0055114	342	0.011
compound eye development	GO:0048749	1	0.011
translation	GO:0006412	93	0.011
regulation of protein maturation	GO:1903317	96	0.011
negative regulation of cellular catabolic process	GO:0031330	47	0.011
positive regulation of cell activation	GO:0050867	158	0.011
response to decreased oxygen levels	GO:0036293	59	0.011
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.011
mitochondrion organization	GO:0007005	134	0.011
regulation of map kinase activity	GO:0043405	120	0.011
multicellular organismal aging	GO:0010259	24	0.011
positive regulation of gtp catabolic process	GO:0033126	85	0.011	Human
inflammatory response	GO:0006954	244	0.011
retina development in camera type eye	GO:0060041	119	0.011
synaptic transmission	GO:0007268	329	0.011
purine nucleotide catabolic process	GO:0006195	211	0.011	Human
spleen development	GO:0048536	39	0.011
regulation of rna splicing	GO:0043484	37	0.011
skin development	GO:0043588	220	0.011
cellular response to extracellular stimulus	GO:0031668	81	0.011
negative regulation of endopeptidase activity	GO:0010951	44	0.011
gene silencing by rna	GO:0031047	19	0.011
central nervous system neuron differentiation	GO:0021953	162	0.011
carbohydrate metabolic process	GO:0005975	230	0.011
blastocyst development	GO:0001824	80	0.011
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.011
positive regulation of protein catabolic process	GO:0045732	60	0.011
rap protein signal transduction	GO:0032486	3	0.011
extrinsic apoptotic signaling pathway	GO:0097191	126	0.011
genetic imprinting	GO:0071514	27	0.011
rna splicing via transesterification reactions	GO:0000375	43	0.011
calcium ion transport	GO:0006816	159	0.011
negative regulation of cytokine production	GO:0001818	84	0.011
negative regulation of multi organism process	GO:0043901	68	0.011
regulation of actin filament based process	GO:0032970	99	0.011
cellular response to oxidative stress	GO:0034599	76	0.011
negative regulation of phosphorylation	GO:0042326	166	0.011
peptidyl serine modification	GO:0018209	83	0.011
cellular response to organic cyclic compound	GO:0071407	87	0.011
sterol homeostasis	GO:0055092	45	0.011
positive regulation of cell cycle process	GO:0090068	61	0.011
response to endoplasmic reticulum stress	GO:0034976	53	0.010
regulation of cell division	GO:0051302	76	0.010
positive regulation of neuron differentiation	GO:0045666	141	0.010
striated muscle tissue development	GO:0014706	293	0.010
chromatin modification	GO:0016568	187	0.010
neural tube development	GO:0021915	160	0.010
activation of mapk activity	GO:0000187	59	0.010
habituation	GO:0046959	3	0.010
protein ubiquitination involved in ubiquitin dependent protein catabolic process	GO:0042787	25	0.010
neuron apoptotic process	GO:0051402	142	0.010

Scrib disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.031
disease of anatomical entity	DOID:7	0.031
disease of cellular proliferation	DOID:14566	0.025
cancer	DOID:162	0.024
organ system cancer	DOID:0050686	0.018
gastrointestinal system cancer	DOID:3119	0.014
central nervous system disease	DOID:331	0.011

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