Mus musculus

8 known processes

Ercc8

excision repaiross-complementing rodent repair deficiency, complementation group 8

(Aliases: 2410022P04Rik,Csa,Ckn1,2810431L23Rik,4631412O06Rik,B130065P18Rik)

Ercc8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.062
Human
peptidyl amino acid modificationGO:00181933360.057
organelle fissionGO:00482851700.055
regulation of cellular amine metabolic processGO:0033238200.055
amine metabolic processGO:0009308450.051
chromatin modificationGO:00165681870.046
positive regulation of cellular amino acid metabolic processGO:004576430.045
regulation of cellular amino acid metabolic processGO:000652150.043
covalent chromatin modificationGO:00165691630.042
cellular amine metabolic processGO:0044106440.040
histone modificationGO:00165701590.039
cellular amino acid metabolic processGO:00065201030.036
chromatin organizationGO:00063252060.036
protein methylationGO:0006479810.033
nuclear divisionGO:00002801580.033
histone methylationGO:0016571710.033
regulation of cellular ketone metabolic processGO:0010565660.031
positive regulation of cellular amine metabolic processGO:003324050.031
dna repairGO:00062811070.030
Human
regulation of organelle organizationGO:00330432890.028
rna processingGO:00063961050.026
cellular ketone metabolic processGO:0042180840.024
peptidyl lysine modificationGO:0018205770.022
macromolecule methylationGO:00434141200.021
cytoplasmic transportGO:00164822340.021
regulation of cell cycle processGO:00105641600.020
methylationGO:00322591340.020
leukocyte differentiationGO:00025213420.020
regionalizationGO:00030023370.019
positive regulation of programmed cell deathGO:00430682180.019
germ cell developmentGO:00072811850.019
myeloid cell differentiationGO:00300992330.018
cellular response to dna damage stimulusGO:00069742070.018
Human
mrna metabolic processGO:0016071840.018
inorganic ion transmembrane transportGO:00986602340.017
regulation of apoptotic signaling pathwayGO:20012331970.017
protein alkylationGO:0008213810.017
reactive oxygen species metabolic processGO:0072593840.017
male gamete generationGO:00482322850.017
dna recombinationGO:0006310920.017
intracellular protein transportGO:00068862040.017
apoptotic signaling pathwayGO:00971903060.017
lipid biosynthetic processGO:00086101790.016
homeostasis of number of cellsGO:00488722100.016
spermatid developmentGO:00072861080.016
heterocycle catabolic processGO:00467002800.016
intracellular mrna localizationGO:000829840.016
cation transmembrane transportGO:00986552660.016
nucleotide metabolic processGO:00091173320.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
cellular lipid metabolic processGO:00442553230.016
respiratory system developmentGO:00605411900.016
negative regulation of protein metabolic processGO:00512482820.016
negative regulation of organelle organizationGO:0010639900.015
protein modification by small protein conjugation or removalGO:00706472070.015
Human
central nervous system neuron differentiationGO:00219531620.015
regulation of cell cycleGO:00517262810.015
regulation of cellular component biogenesisGO:00440871810.015
purine ribonucleotide metabolic processGO:00091502900.015
oocyte axis specificationGO:000730920.015
nucleoside phosphate metabolic processGO:00067533380.015
histone lysine methylationGO:0034968500.015
meiotic cell cycleGO:00513211220.015
posttranscriptional regulation of gene expressionGO:00106081550.015
positive regulation of apoptotic processGO:00430652170.015
hematopoietic progenitor cell differentiationGO:00022441430.015
b cell differentiationGO:0030183780.014
regulation of leukocyte differentiationGO:19021051590.014
oocyte constructionGO:000730820.014
compound eye developmentGO:004874910.014
protein acylationGO:0043543640.014
nucleobase containing small molecule metabolic processGO:00550863520.014
regulation of hormone levelsGO:00108172110.014
inorganic cation transmembrane transportGO:00986622070.014
spermatid differentiationGO:00485151150.014
organonitrogen compound biosynthetic processGO:19015661920.014
cellular macromolecule catabolic processGO:00442652060.014
Human
retina development in camera type eyeGO:00600411190.014
neural tube developmentGO:00219151600.014
negative regulation of cellular component organizationGO:00511291940.014
cation transportGO:00068123990.014
action potentialGO:0001508780.014
negative regulation of cellular amino acid metabolic processGO:004576300.013
aromatic compound catabolic processGO:00194392860.013
regulation of proteolysisGO:00301621640.013
positive regulation of protein modification processGO:00314012990.013
ossificationGO:00015032160.013
skeletal system developmentGO:00015013560.013
immune effector processGO:00022523210.013
organophosphate catabolic processGO:00464342320.013
carbohydrate derivative catabolic processGO:19011362310.013
ribonucleotide catabolic processGO:00092612080.013
cellular protein catabolic processGO:00442571550.013
Human
cellular nitrogen compound catabolic processGO:00442702800.013
t cell activationGO:00421102890.012
regulation of mapk cascadeGO:00434082480.012
glycosyl compound metabolic processGO:19016572460.012
organophosphate biosynthetic processGO:00904071220.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
modification dependent macromolecule catabolic processGO:00436321330.012
Human
cellular response to hormone stimulusGO:00328701500.012
locomotory behaviorGO:00076261950.012
purine containing compound metabolic processGO:00725213110.012
protein localization to organelleGO:00333651850.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.012
nuclear transportGO:00511691390.012
engulfment of apoptotic cellGO:004365230.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
nucleotide catabolic processGO:00091662170.012
purine nucleotide metabolic processGO:00061633020.012
proteasomal protein catabolic processGO:0010498980.012
Human
purine containing compound catabolic processGO:00725232130.012
positive regulation of organelle organizationGO:00106381280.012
membrane organizationGO:00610242450.012
multicellular organism growthGO:00352641610.012
establishment or maintenance of cytoskeleton polarityGO:003095220.012
protein ubiquitinationGO:00165671710.011
Human
cellular chemical homeostasisGO:00550822150.011
mapk cascadeGO:00001652810.011
anatomical structure homeostasisGO:00602491450.011
spermatogenesisGO:00072832840.011
small molecule biosynthetic processGO:00442831320.011
ras protein signal transductionGO:0007265770.011
organic cyclic compound catabolic processGO:19013612950.011
regulation of cell adhesionGO:00301551540.011
mitotic cell cycleGO:00002781950.011
microtubule based processGO:00070172360.011
meiotic nuclear divisionGO:00071261150.011
ribose phosphate metabolic processGO:00196932910.011
lung developmentGO:00303241640.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
negative regulation of cellular amine metabolic processGO:003323910.011
mrna processingGO:0006397630.011
regulation of membrane potentialGO:00423911920.011
microtubule cytoskeleton organization involved in mitosisGO:190285040.011
meiotic cell cycle processGO:1903046770.011
nitrogen compound transportGO:00717052710.011
nucleocytoplasmic transportGO:00069131390.011
multicellular organismal signalingGO:0035637910.011
histone acetylationGO:0016573410.011
male meiosis iGO:0007141160.011
regulation of transferase activityGO:00513382630.011
nucleoside triphosphate catabolic processGO:00091432050.011
ribonucleotide metabolic processGO:00092592910.011
gene silencingGO:0016458380.011
regulation of cellular catabolic processGO:00313292420.011
reactive nitrogen species metabolic processGO:200105700.011
ubiquitin dependent protein catabolic processGO:00065111290.011
Human
maternal determination of anterior posterior axis embryoGO:000835820.011
mrna splicing via spliceosomeGO:0000398430.010
positive regulation of nervous system developmentGO:00519622210.010
transmission of nerve impulseGO:0019226760.010
inflammatory responseGO:00069542440.010
positive regulation of cell deathGO:00109422240.010
nucleoside phosphate catabolic processGO:19012922220.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
peptidyl lysine acetylationGO:0018394450.010
transmembrane transportGO:00550854120.010
synapse organizationGO:00508081250.010
fat cell differentiationGO:00454441600.010
cell adhesionGO:00071553290.010
nucleoside metabolic processGO:00091162460.010
digestive tract developmentGO:00485651900.010
regulation of cytoplasmic transportGO:19036491120.010
exocytosisGO:00068871210.010
meiosis iGO:0007127600.010
cellular response to lipidGO:00713961450.010
sperm motilityGO:0030317470.010
developmental maturationGO:00217001930.010

Ercc8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
immune system diseaseDOID:291400.023
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.020
hematopoietic system diseaseDOID:7400.014
central nervous system diseaseDOID:33100.012
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
anemiaDOID:235500.011
congenital hypoplastic anemiaDOID:134200.011
aplastic anemiaDOID:1244900.011
bone marrow diseaseDOID:496100.011