Mus musculus

121 known processes

Ercc1

excision repair cross-complementing rodent repair deficiency, complementation group 1

(Aliases: Ercc-1)

Ercc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.147
apoptotic signaling pathwayGO:00971903060.134
regulation of hydrolase activityGO:00513362460.098
regulation of transferase activityGO:00513382630.093
regulation of kinase activityGO:00435492490.093
positive regulation of protein phosphorylationGO:00019342420.087
cellular amino acid metabolic processGO:00065201030.084
protein maturationGO:00516041760.076
positive regulation of protein modification processGO:00314012990.076
regulation of organelle organizationGO:00330432890.073
muscle tissue developmentGO:00605373080.072
regulation of cell motilityGO:20001452360.069
protein processingGO:00164851630.068
response to oxidative stressGO:00069791230.068
positive regulation of growthGO:00459271040.067
positive regulation of cellular amino acid metabolic processGO:004576430.063
cellular response to dna damage stimulusGO:00069742070.061
cell adhesionGO:00071553290.058
macromolecule catabolic processGO:00090572810.058
inflammatory responseGO:00069542440.056
chromatin organizationGO:00063252060.056
purine nucleoside triphosphate catabolic processGO:00091462030.056
muscle fiber developmentGO:0048747760.055
regulation of protein kinase activityGO:00458592320.052
gland developmentGO:00487323300.052
striated muscle tissue developmentGO:00147062930.052
ras protein signal transductionGO:0007265770.052
cell growthGO:00160491300.051
regulation of apoptotic signaling pathwayGO:20012331970.050
response to organic cyclic compoundGO:00140701980.049
negative regulation of molecular functionGO:00440922580.048
positive regulation of cellular amine metabolic processGO:003324050.048
spermatogenesisGO:00072832840.047
negative regulation of intracellular signal transductionGO:19025321670.047
negative regulation of phosphorus metabolic processGO:00105631840.047
skeletal system developmentGO:00015013560.046
blood vessel morphogenesisGO:00485142850.045
oxidation reduction processGO:00551143420.045
protein modification by small protein conjugation or removalGO:00706472070.045
cellular ketone metabolic processGO:0042180840.045
negative regulation of phosphorylationGO:00423261660.044
reactive oxygen species metabolic processGO:0072593840.043
regulation of proteolysisGO:00301621640.043
regulation of cell migrationGO:00303342190.042
ossificationGO:00015032160.041
dna repairGO:00062811070.041
negative regulation of protein metabolic processGO:00512482820.040
muscle cell differentiationGO:00426922610.040
cellular macromolecule catabolic processGO:00442652060.039
stem cell differentiationGO:00488632680.039
regulation of anatomical structure sizeGO:00900661780.038
posttranscriptional regulation of gene expressionGO:00106081550.038
multi multicellular organism processGO:00447061090.038
transmembrane transportGO:00550854120.038
small gtpase mediated signal transductionGO:0007264970.038
organic cyclic compound catabolic processGO:19013612950.037
male gamete generationGO:00482322850.037
regulation of endopeptidase activityGO:0052548890.036
cellular lipid metabolic processGO:00442553230.036
skeletal muscle organ developmentGO:00605381630.036
negative regulation of cellular protein metabolic processGO:00322692470.036
regulation of cellular response to stressGO:00801351590.036
regulation of mitotic cell cycleGO:00073461260.036
mitotic cell cycle processGO:19030471590.035
response to lipopolysaccharideGO:00324961280.035
negative regulation of cell cycleGO:00457861230.035
multicellular organism growthGO:00352641610.035
ribose phosphate metabolic processGO:00196932910.035
nucleobase containing small molecule metabolic processGO:00550863520.035
cellular amine metabolic processGO:0044106440.034
regulation of cellular catabolic processGO:00313292420.034
purine containing compound metabolic processGO:00725213110.034
lung developmentGO:00303241640.034
neuron apoptotic processGO:00514021420.034
camera type eye developmentGO:00430102660.034
positive regulation of programmed cell deathGO:00430682180.034
nucleoside phosphate metabolic processGO:00067533380.034
regulation of cellular amino acid metabolic processGO:000652150.033
positive regulation of cell deathGO:00109422240.033
cellular nitrogen compound catabolic processGO:00442702800.033
positive regulation of proteolysisGO:0045862850.032
multicellular organismal homeostasisGO:00488711640.032
positive regulation of peptidase activityGO:0010952490.032
carbohydrate derivative catabolic processGO:19011362310.032
developmental growth involved in morphogenesisGO:00605601380.032
ribonucleotide metabolic processGO:00092592910.032
purine ribonucleotide metabolic processGO:00091502900.032
nuclear divisionGO:00002801580.031
Fly
heterocycle catabolic processGO:00467002800.031
regulation of cellular amine metabolic processGO:0033238200.031
gonad developmentGO:00084061410.031
intrinsic apoptotic signaling pathwayGO:00971931320.031
negative regulation of protein phosphorylationGO:00019331260.031
regulation of chromosome organizationGO:0033044830.031
tissue homeostasisGO:00018941150.030
regulation of cell cycleGO:00517262810.030
positive regulation of transferase activityGO:00513471670.030
negative regulation of immune system processGO:00026832090.030
amine metabolic processGO:0009308450.030
neuron deathGO:00709971540.030
digestive system developmentGO:00551232000.030
purine ribonucleotide catabolic processGO:00091542080.029
epithelial cell developmentGO:00020641590.029
chromatin modificationGO:00165681870.029
histone modificationGO:00165701590.029
regulation of cell sizeGO:0008361720.029
organelle assemblyGO:00709251770.029
regulation of cell cycle processGO:00105641600.028
respiratory system developmentGO:00605411900.028
organophosphate catabolic processGO:00464342320.028
immune effector processGO:00022523210.028
chemotaxisGO:00069352470.028
regulation of peptidase activityGO:0052547960.028
glycosyl compound metabolic processGO:19016572460.028
regulation of mapk cascadeGO:00434082480.028
negative regulation of phosphate metabolic processGO:00459361840.027
regulation of defense responseGO:00313472330.027
cellular response to lipopolysaccharideGO:0071222770.027
blood circulationGO:00080151950.027
regulation of cellular component biogenesisGO:00440871810.027
regulation of protein processingGO:0070613960.027
organelle fissionGO:00482851700.027
Fly
signal transduction by p53 class mediatorGO:0072331510.027
hematopoietic progenitor cell differentiationGO:00022441430.027
regulation of cellular component sizeGO:00325351210.026
positive regulation of kinase activityGO:00336741550.026
epithelial cell proliferationGO:00506731740.026
proteolysis involved in cellular protein catabolic processGO:00516031470.026
purine ribonucleoside triphosphate metabolic processGO:00092052200.026
cellular response to biotic stimulusGO:0071216920.026
nucleoside metabolic processGO:00091162460.026
sensory perceptionGO:00076002450.026
protein modification by small protein conjugationGO:00324461870.026
response to growth factorGO:00708481980.026
homeostasis of number of cellsGO:00488722100.025
regulation of cell cycle phase transitionGO:1901987770.025
response to temperature stimulusGO:0009266550.025
cell type specific apoptotic processGO:00972852680.025
positive regulation of apoptotic processGO:00430652170.025
stem cell developmentGO:00488642190.025
cellular response to molecule of bacterial originGO:0071219830.024
protein ubiquitinationGO:00165671710.024
regulation of cytoskeleton organizationGO:00514931220.024
negative regulation of protein maturationGO:1903318790.024
zymogen activationGO:0031638410.024
modification dependent protein catabolic processGO:00199411330.024
cell cycle checkpointGO:0000075470.024
microtubule cytoskeleton organizationGO:00002261570.024
modification dependent macromolecule catabolic processGO:00436321330.024
mapk cascadeGO:00001652810.024
cell maturationGO:00484691270.024
regulation of protein localizationGO:00328802310.024
membrane organizationGO:00610242450.024
cytokine productionGO:00018163190.024
regulation of blood pressureGO:0008217930.024
positive regulation of protein kinase activityGO:00458601440.023
limb developmentGO:00601731660.023
positive regulation of hydrolase activityGO:00513451480.023
wnt signaling pathwayGO:00160551880.023
positive regulation of apoptotic signaling pathwayGO:2001235950.023
regulation of mitotic cell cycle phase transitionGO:1901990730.023
extrinsic apoptotic signaling pathwayGO:00971911260.023
germ cell developmentGO:00072811850.023
purine nucleotide metabolic processGO:00061633020.023
response to reactive oxygen speciesGO:0000302560.023
negative regulation of protein modification processGO:00314001630.022
response to radiationGO:00093141650.022
nitrogen compound transportGO:00717052710.022
response to molecule of bacterial originGO:00022371430.022
locomotory behaviorGO:00076261950.022
cellular response to growth factor stimulusGO:00713631970.022
fat cell differentiationGO:00454441600.022
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.022
regulation of vesicle mediated transportGO:00606271390.021
development of primary sexual characteristicsGO:00451371430.021
myeloid cell homeostasisGO:00022621140.021
organophosphate biosynthetic processGO:00904071220.021
response to heatGO:0009408270.021
regulation of cysteine type endopeptidase activityGO:2000116650.021
peptidyl amino acid modificationGO:00181933360.021
response to ionizing radiationGO:0010212420.021
endocytosisGO:00068971680.021
mitotic cell cycleGO:00002781950.021
regulation of erk1 and erk2 cascadeGO:0070372710.020
purine nucleoside metabolic processGO:00422782410.020
molting cycleGO:0042303900.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
regulation of cellular ketone metabolic processGO:0010565660.020
appendage developmentGO:00487361660.020
respiratory tube developmentGO:00303231670.020
regulation of bindingGO:00510981110.020
negative regulation of cellular component organizationGO:00511291940.020
regulation of cytokine productionGO:00018172660.020
peptidyl tyrosine modificationGO:00182121450.020
regulation of cell growthGO:0001558910.019
extracellular structure organizationGO:00430621480.019
digestive tract developmentGO:00485651900.019
nucleotide metabolic processGO:00091173320.019
negative regulation of proteolysisGO:0045861740.019
protein localization to organelleGO:00333651850.019
response to light stimulusGO:00094161350.019
regulation of protein transportGO:00512231630.019
bone developmentGO:00603481200.019
actin cytoskeleton organizationGO:00300362200.019
methylationGO:00322591340.019
anatomical structure homeostasisGO:00602491450.019
negative regulation of neuron deathGO:1901215980.019
negative regulation of cell proliferationGO:00082852960.019
nucleoside triphosphate metabolic processGO:00091412300.019
rna processingGO:00063961050.019
negative regulation of cell cycle processGO:0010948690.018
branching morphogenesis of an epithelial tubeGO:00487541590.018
morphogenesis of embryonic epitheliumGO:00163311590.018
glycosyl compound catabolic processGO:19016582060.018
response to steroid hormoneGO:0048545560.018
axonogenesisGO:00074092740.018
purine ribonucleoside metabolic processGO:00461282410.018
carbohydrate derivative biosynthetic processGO:19011371830.018
cellular protein catabolic processGO:00442571550.018
negative regulation of lymphocyte activationGO:0051250910.018
sensory organ morphogenesisGO:00905962420.018
peptidyl tyrosine phosphorylationGO:00181081430.018
gtp catabolic processGO:00061841430.018
ribonucleoside metabolic processGO:00091192450.018
protein catabolic processGO:00301632210.018
meiotic nuclear divisionGO:00071261150.018
Fly
regulation of protein maturationGO:1903317960.018
regulation of cell adhesionGO:00301551540.018
organonitrogen compound biosynthetic processGO:19015661920.018
regulation of system processGO:00440572000.018
aromatic compound catabolic processGO:00194392860.018
negative regulation of kinase activityGO:0033673810.018
purine nucleoside catabolic processGO:00061522050.018
cell divisionGO:00513011200.018
nucleotide catabolic processGO:00091662170.018
ribonucleotide catabolic processGO:00092612080.018
lipid biosynthetic processGO:00086101790.017
dna conformation changeGO:0071103370.017
regulation of ion transportGO:00432692150.017
negative regulation of transferase activityGO:0051348850.017
positive regulation of nervous system developmentGO:00519622210.017
regulation of body fluid levelsGO:00508781620.017
ubiquitin dependent protein catabolic processGO:00065111290.017
microtubule based processGO:00070172360.017
nucleoside phosphate catabolic processGO:19012922220.017
regulation of neuron deathGO:19012141340.016
regulation of endocytosisGO:0030100690.016
dna replicationGO:0006260520.016
regulation of neuron apoptotic processGO:00435231220.016
ameboidal type cell migrationGO:00016671280.016
morphogenesis of a branching structureGO:00017632030.016
g1 s transition of mitotic cell cycleGO:0000082570.016
cation homeostasisGO:00550802120.016
gene silencingGO:0016458380.016
cognitionGO:00508901490.016
skeletal muscle fiber developmentGO:0048741580.016
regulation of cell substrate adhesionGO:0010810730.016
response to superoxideGO:0000303160.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
myeloid cell differentiationGO:00300992330.016
positive regulation of cytokine productionGO:00018191740.016
response to acid chemicalGO:00011011110.015
wound healingGO:00420601570.015
purine nucleotide catabolic processGO:00061952110.015
regulation of cell activationGO:00508652890.015
response to uvGO:0009411440.015
lymphocyte mediated immunityGO:00024491390.015
feeding behaviorGO:0007631620.015
fertilizationGO:00095661270.015
regulation of leukocyte differentiationGO:19021051590.015
positive regulation of cysteine type endopeptidase activityGO:2001056390.015
single organismal cell cell adhesionGO:00163371310.015
compound eye developmentGO:004874910.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
nephron epithelium developmentGO:0072009920.015
regulation of protein serine threonine kinase activityGO:00719001570.015
regulation of cellular response to growth factor stimulusGO:0090287820.015
regulation of actin filament based processGO:0032970990.015
sa node cell action potentialGO:008601540.015
response to organonitrogen compoundGO:00102432460.015
cellular response to lipidGO:00713961450.015
protein methylationGO:0006479810.015
proteasomal protein catabolic processGO:0010498980.015
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.015
myeloid leukocyte differentiationGO:00025731190.015
positive regulation of cell migrationGO:00303351090.014
regulation of vasculature developmentGO:1901342880.014
spermatid differentiationGO:00485151150.014
striated muscle cell developmentGO:00550021250.014
myosin filament assemblyGO:003103420.014
positive regulation of mapk cascadeGO:00434101700.014
regulation of purine nucleotide metabolic processGO:19005421690.014
glycoprotein metabolic processGO:00091001160.014
regulation of wnt signaling pathwayGO:00301111230.014
covalent chromatin modificationGO:00165691630.014
translationGO:0006412930.014
circulatory system processGO:00030131970.014
cell substrate adhesionGO:00315891300.014
negative regulation of mitotic cell cycle phase transitionGO:1901991450.014
heart contractionGO:0060047930.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
positive regulation of bindingGO:0051099490.014
meiotic cell cycleGO:00513211220.014
Fly
forebrain developmentGO:00309003020.014
myosin filament organizationGO:003103330.014
developmental maturationGO:00217001930.014
regulation of ossificationGO:00302781120.014
regulation of neuron differentiationGO:00456642810.014
protein secretionGO:00093061110.014
nucleic acid phosphodiester bond hydrolysisGO:0090305490.014
response to extracellular stimulusGO:00099911270.014
negative regulation of cellular amine metabolic processGO:003323910.013
regulation of cell projection organizationGO:00313442060.013
positive regulation of neuron differentiationGO:00456661410.013
regulation of protein bindingGO:0043393600.013
regulation of antimicrobial humoral responseGO:000275930.013
antimicrobial peptide biosynthetic processGO:000277720.013
morphogenesis of a branching epitheliumGO:00611381930.013
negative regulation of organelle organizationGO:0010639900.013
spermatid developmentGO:00072861080.013
regulation of homeostatic processGO:00328441820.013
negative regulation of dna replicationGO:000815640.013
developmental cell growthGO:0048588840.013
purine nucleoside triphosphate metabolic processGO:00091442260.013
nucleoside catabolic processGO:00091642060.013
negative regulation of mitotic cell cycleGO:0045930580.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
purine ribonucleoside catabolic processGO:00461302050.013
monocarboxylic acid metabolic processGO:00327871910.013
regulation of chromatin modificationGO:1903308570.013
cardiac muscle tissue developmentGO:00487381300.013
peptidyl serine phosphorylationGO:0018105740.013
regulation of inflammatory responseGO:00507271470.013
negative regulation of leukocyte differentiationGO:1902106510.013
purine containing compound catabolic processGO:00725232130.013
t cell activationGO:00421102890.013
regulation of extent of cell growthGO:0061387520.013
regulation of lymphocyte activationGO:00512492400.013
negative regulation of protein processingGO:0010955790.013
mrna metabolic processGO:0016071840.013
ribonucleoside catabolic processGO:00424542060.013
organelle localizationGO:00516401790.013
regulation of actin cytoskeleton organizationGO:0032956840.013
nucleocytoplasmic transportGO:00069131390.012
mitotic cell cycle checkpointGO:0007093310.012
rac protein signal transductionGO:0016601130.012
maintenance of locationGO:0051235890.012
heart morphogenesisGO:00030071780.012
regulation of neural precursor cell proliferationGO:2000177700.012
connective tissue developmentGO:00614481790.012
regulation of angiogenesisGO:0045765810.012
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.012
cellular response to radiationGO:0071478280.012
negative regulation of wnt signaling pathwayGO:0030178730.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
regulation of dna replicationGO:0006275170.012
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.012
positive regulation of cell motilityGO:20001471160.012
single organism cell adhesionGO:00986021560.012
regulation of secretion by cellGO:19035302490.012
negative regulation of growthGO:0045926990.012
regulation of map kinase activityGO:00434051200.012
rho protein signal transductionGO:0007266320.012
response to oxygen levelsGO:0070482620.012
positive regulation of cell developmentGO:00107202370.012
negative regulation of phagocytosisGO:005076540.012
urogenital system developmentGO:00016552610.012
regulation of multi organism processGO:00439001110.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
phagocytosisGO:0006909660.012
skeletal system morphogenesisGO:00487052030.012
immune response regulating signaling pathwayGO:00027641250.012
cellular response to amino acid stimulusGO:0071230290.012
response to oxygen radicalGO:0000305160.012
positive regulation of organelle organizationGO:00106381280.012
g protein coupled receptor signaling pathwayGO:00071862430.012
mitotic cytokinesisGO:000028140.012
regulation of establishment of protein localizationGO:00702011810.012
positive regulation of cell adhesionGO:0045785800.011
sperm motilityGO:0030317470.011
fibroblast proliferationGO:0048144350.011
nucleoside triphosphate catabolic processGO:00091432050.011
viral gene expressionGO:001908030.011
cartilage developmentGO:00512161400.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
positive regulation of cell growthGO:0030307330.011
regulation of response to woundingGO:19030341890.011
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.011
establishment of organelle localizationGO:00516561220.011
macromolecule methylationGO:00434141200.011
epidermal growth factor receptor signaling pathwayGO:0007173280.011
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.011
innate immune responseGO:00450871570.011
organonitrogen compound catabolic processGO:19015652640.011
negative regulation of ligase activityGO:005135230.011
negative regulation of mapk cascadeGO:0043409650.011
dna packagingGO:0006323300.011
oocyte constructionGO:000730820.011
skin developmentGO:00435882200.011
regulation of renin secretion into blood streamGO:190013340.011
protein polymerizationGO:0051258570.011
leukocyte differentiationGO:00025213420.011
regulation of striated muscle cell differentiationGO:0051153810.011
regulation of protein catabolic processGO:00421761080.011
erk1 and erk2 cascadeGO:0070371770.011
leukocyte mediated cytotoxicityGO:0001909620.011
regulation of histone modificationGO:0031056560.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.011
embryonic organ morphogenesisGO:00485622760.011
protein targetingGO:00066051430.011
protein polyubiquitinationGO:0000209330.011
negative regulation of cell activationGO:00508661110.011
reactive nitrogen species metabolic processGO:200105700.011
cytoplasmic transportGO:00164822340.011
lymphocyte homeostasisGO:0002260640.011
telencephalon developmentGO:00215371860.011
positive regulation of chromosome organizationGO:2001252330.011
rhythmic processGO:00485111740.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
tube formationGO:00351481400.011
cell cycle g1 s phase transitionGO:0044843570.011
guanosine containing compound catabolic processGO:19010691440.010
neural tube developmentGO:00219151600.010
angiogenesisGO:00015252010.010
negative regulation of cell migrationGO:0030336590.010
antimicrobial peptide productionGO:000277520.010
response to drugGO:0042493750.010
muscle cell developmentGO:00550011330.010
regulation of protein stabilityGO:0031647520.010
regulation of interleukin 8 productionGO:003267730.010
vegf activated neuropilin signaling pathwayGO:003819020.010
regulation of transmembrane transportGO:00347621280.010
regulation of gtp catabolic processGO:00331241130.010
organ growthGO:00352651170.010
retina development in camera type eyeGO:00600411190.010
learning or memoryGO:00076111480.010
negative regulation of defense responseGO:0031348770.010
mesenchyme developmentGO:00604851520.010
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.010
regulation of fibroblast proliferationGO:0048145340.010
cellular response to acid chemicalGO:0071229680.010
regulation of axon extensionGO:0030516430.010
response to inorganic substanceGO:0010035960.010
negative regulation of neuron apoptotic processGO:0043524920.010
leukocyte apoptotic processGO:0071887710.010
appendage morphogenesisGO:00351071490.010
positive regulation of immune effector processGO:00026991070.010
regulation of autophagyGO:0010506300.010

Ercc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.131
disease of cellular proliferationDOID:1456600.131
cancerDOID:16200.131
disease of metabolismDOID:001466700.021
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
sensory system diseaseDOID:005015500.012
inherited metabolic disorderDOID:65500.011