Mus musculus

123 known processes

Ercc2

excision repair cross-complementing rodent repair deficiency, complementation group 2

(Aliases: AU020867,XPD,AW240756,AA407812,Ercc-2)

Ercc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
homeostasis of number of cellsGO:00488722100.302
cellular response to dna damage stimulusGO:00069742070.180
spermatogenesisGO:00072832840.141
gland developmentGO:00487323300.130
carbohydrate derivative biosynthetic processGO:19011371830.126
cell adhesionGO:00071553290.116
regionalizationGO:00030023370.113
myeloid cell differentiationGO:00300992330.079
developmental maturationGO:00217001930.078
glycoprotein metabolic processGO:00091001160.074
actin cytoskeleton organizationGO:00300362200.074
protein modification by small protein conjugation or removalGO:00706472070.071
gonad developmentGO:00084061410.066
dna repairGO:00062811070.061
skeletal system developmentGO:00015013560.058
nucleotide metabolic processGO:00091173320.057
male gamete generationGO:00482322850.057
regulation of cell cycleGO:00517262810.054
carbohydrate metabolic processGO:00059752300.054
placenta developmentGO:00018901400.053
organonitrogen compound biosynthetic processGO:19015661920.052
dna metabolic processGO:00062593030.051
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.051
aromatic compound catabolic processGO:00194392860.051
negative regulation of cell sizeGO:004579230.050
regulation of defense responseGO:00313472330.049
purine nucleotide metabolic processGO:00061633020.049
cation transportGO:00068123990.048
notch signaling pathwayGO:0007219710.047
purine containing compound metabolic processGO:00725213110.046
nucleoside phosphate metabolic processGO:00067533380.045
glycoprotein biosynthetic processGO:0009101890.043
stem cell developmentGO:00488642190.042
regulation of synaptic growth at neuromuscular junctionGO:000858240.042
methylationGO:00322591340.042
organonitrogen compound catabolic processGO:19015652640.042
response to uvGO:0009411440.041
epithelial tube morphogenesisGO:00605623030.041
epithelial cell proliferationGO:00506731740.041
regulation of cellular response to stressGO:00801351590.040
development of primary sexual characteristicsGO:00451371430.040
meiotic cell cycleGO:00513211220.039
embryonic epithelial tube formationGO:00018381300.039
central nervous system neuron differentiationGO:00219531620.039
positive regulation of protein phosphorylationGO:00019342420.038
negative regulation of cellular protein metabolic processGO:00322692470.038
cellular response to hormone stimulusGO:00328701500.036
digestive tract developmentGO:00485651900.036
skin developmentGO:00435882200.035
compound eye developmentGO:004874910.035
translationGO:0006412930.034
muscle cell differentiationGO:00426922610.034
protein ubiquitinationGO:00165671710.034
negative regulation of cell fate specificationGO:000999640.033
protein localization to organelleGO:00333651850.033
multi multicellular organism processGO:00447061090.033
cellular response to organonitrogen compoundGO:00714171450.032
negative regulation of cellular amino acid metabolic processGO:004576300.032
purine nucleoside metabolic processGO:00422782410.032
stem cell differentiationGO:00488632680.032
positive regulation of purine nucleotide metabolic processGO:19005441140.031
reactive oxygen species metabolic processGO:0072593840.031
nucleobase containing small molecule metabolic processGO:00550863520.030
protein maturationGO:00516041760.030
forebrain developmentGO:00309003020.030
ribonucleotide metabolic processGO:00092592910.030
cell fate commitmentGO:00451652100.029
nucleoside metabolic processGO:00091162460.029
spermatid developmentGO:00072861080.029
lateral inhibitionGO:004633110.029
muscle tissue developmentGO:00605373080.029
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.029
bone developmentGO:00603481200.029
regulation of vesicle mediated transportGO:00606271390.029
negative regulation of cellular amine metabolic processGO:003323910.028
generation of precursor metabolites and energyGO:00060911030.028
positive regulation of cell projection organizationGO:0031346950.028
protein catabolic processGO:00301632210.028
regulation of cellular ketone metabolic processGO:0010565660.028
digestive system developmentGO:00551232000.027
regulation of cellular amine metabolic processGO:0033238200.027
cellular amine metabolic processGO:0044106440.027
peptide secretionGO:00027901140.027
multicellular organismal homeostasisGO:00488711640.027
mapk cascadeGO:00001652810.027
innate immune responseGO:00450871570.027
organic cyclic compound catabolic processGO:19013612950.026
positive regulation of cellular amine metabolic processGO:003324050.026
divalent inorganic cation transportGO:00725111780.026
gastrulationGO:00073691160.026
regulation of secretion by cellGO:19035302490.025
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.025
oocyte axis specificationGO:000730920.025
cellular response to growth factor stimulusGO:00713631970.025
embryonic limb morphogenesisGO:00303261260.025
response to oxidative stressGO:00069791230.025
histone modificationGO:00165701590.024
dendrite developmentGO:00163581150.024
retina development in camera type eyeGO:00600411190.024
negative regulation of synaptic vesicle transportGO:190280430.024
dorsal ventral axon guidanceGO:003356330.024
response to radiationGO:00093141650.024
regulation of kinase activityGO:00435492490.024
glycosylationGO:0070085620.024
cellular response to peptide hormone stimulusGO:0071375920.023
regulation of response to dna damage stimulusGO:2001020340.023
epidermis developmentGO:00085441870.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.023
regulation of cell projection organizationGO:00313442060.023
ras protein signal transductionGO:0007265770.023
hormone secretionGO:00468791280.023
regulation of leukocyte differentiationGO:19021051590.022
macromolecule catabolic processGO:00090572810.022
regulation of sequence specific dna binding transcription factor activityGO:00510901060.022
purine ribonucleotide catabolic processGO:00091542080.022
response to organonitrogen compoundGO:00102432460.022
amine metabolic processGO:0009308450.022
purine ribonucleotide metabolic processGO:00091502900.022
proteolysis involved in cellular protein catabolic processGO:00516031470.022
neural tube closureGO:0001843900.022
organophosphate biosynthetic processGO:00904071220.022
respiratory system developmentGO:00605411900.022
nucleotide biosynthetic processGO:0009165780.022
cellular protein catabolic processGO:00442571550.022
endodermal cell fate specificationGO:000171440.022
positive regulation of neuron differentiationGO:00456661410.022
response to inorganic substanceGO:0010035960.022
organelle fissionGO:00482851700.021
negative regulation of protein phosphorylationGO:00019331260.021
cell type specific apoptotic processGO:00972852680.021
cellular response to peptideGO:1901653920.021
single organismal cell cell adhesionGO:00163371310.021
cellular ketone metabolic processGO:0042180840.021
myeloid leukocyte differentiationGO:00025731190.021
mitotic cell cycleGO:00002781950.021
embryonic organ morphogenesisGO:00485622760.021
establishment or maintenance of cytoskeleton polarityGO:003095220.021
leukocyte differentiationGO:00025213420.021
positive regulation of apoptotic processGO:00430652170.021
cell recognitionGO:0008037830.021
negative regulation of protein metabolic processGO:00512482820.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
regulation of secretionGO:00510462740.020
segmentationGO:0035282930.020
t cell activationGO:00421102890.020
purine ribonucleoside triphosphate metabolic processGO:00092052200.020
oxidation reduction processGO:00551143420.020
macromolecule methylationGO:00434141200.020
protein modification by small protein conjugationGO:00324461870.020
purine containing compound catabolic processGO:00725232130.020
chromatin modificationGO:00165681870.020
spinal cord developmentGO:0021510810.019
respiratory tube developmentGO:00303231670.019
molting cycleGO:0042303900.019
regulation of cellular catabolic processGO:00313292420.019
nucleoside catabolic processGO:00091642060.019
regulation of establishment of protein localizationGO:00702011810.019
purine nucleotide catabolic processGO:00061952110.019
cell maturationGO:00484691270.019
mesodermal cell migrationGO:000807840.019
macromolecule glycosylationGO:0043413550.019
regulation of organelle organizationGO:00330432890.019
regulation of antimicrobial peptide biosynthetic processGO:000280510.019
positive regulation of nucleotide metabolic processGO:00459811140.018
positive regulation of cyclic nucleotide metabolic processGO:0030801240.018
positive regulation of defense responseGO:00313491240.018
cell divisionGO:00513011200.018
oocyte constructionGO:000730820.018
nucleoside phosphate catabolic processGO:19012922220.018
negative regulation of protein modification processGO:00314001630.018
nucleoside triphosphate metabolic processGO:00091412300.018
ribose phosphate metabolic processGO:00196932910.018
regulation of transferase activityGO:00513382630.018
glycosyl compound metabolic processGO:19016572460.018
nitrogen compound transportGO:00717052710.018
nuclear divisionGO:00002801580.018
positive regulation of cell developmentGO:00107202370.018
germ cell developmentGO:00072811850.018
regulation of neurotransmitter levelsGO:0001505870.018
camera type eye developmentGO:00430102660.018
neuron deathGO:00709971540.017
b cell activationGO:00421131610.017
negative regulation of phosphate metabolic processGO:00459361840.017
appendage developmentGO:00487361660.017
digestive tract morphogenesisGO:00485461470.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
posttranscriptional regulation of gene expressionGO:00106081550.017
cellular response to oxidative stressGO:0034599760.017
hindbrain developmentGO:00309021280.017
regulation of lymphocyte activationGO:00512492400.017
regulation of purine nucleotide metabolic processGO:19005421690.017
heterocycle catabolic processGO:00467002800.017
cell fate determination involved in pattern specificationGO:006058210.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
protein localization to nucleusGO:00345041210.016
myeloid cell homeostasisGO:00022621140.016
smoothened signaling pathwayGO:00072241050.016
positive regulation of response to woundingGO:1903036660.016
positive regulation of nervous system developmentGO:00519622210.016
primary neural tube formationGO:0014020950.016
epithelial tube formationGO:00721751300.016
cation transmembrane transportGO:00986552660.016
regulation of protein catabolic processGO:00421761080.016
cd4 positive alpha beta t cell activationGO:0035710450.016
regulation of bindingGO:00510981110.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
embryonic skeletal system developmentGO:00487061200.016
locomotory behaviorGO:00076261950.016
rna processingGO:00063961050.016
bmp signaling pathwayGO:0030509930.016
alpha beta t cell activationGO:0046631910.016
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.016
response to steroid hormoneGO:0048545560.016
apical constrictionGO:000338340.016
ion transmembrane transportGO:00342203610.016
multicellular organism growthGO:00352641610.016
engulfment of apoptotic cellGO:004365230.016
endocytosisGO:00068971680.015
protein processingGO:00164851630.015
single organism cell adhesionGO:00986021560.015
regulation of cell shapeGO:0008360390.015
insulin secretionGO:0030073890.015
wnt signaling pathwayGO:00160551880.015
somitogenesisGO:0001756690.015
cyclic nucleotide biosynthetic processGO:0009190440.015
regulation of carbohydrate metabolic processGO:0006109750.015
anatomical structure homeostasisGO:00602491450.015
cellular amino acid metabolic processGO:00065201030.015
positive regulation of protein catabolic processGO:0045732600.015
regulation of protein localizationGO:00328802310.014
regulation of protein kinase activityGO:00458592320.014
trunk segmentationGO:003529040.014
neuron projection guidanceGO:00974851410.014
cytoplasmic transportGO:00164822340.014
modification dependent protein catabolic processGO:00199411330.014
regulation of notch signaling pathwayGO:0008593350.014
response to molecule of bacterial originGO:00022371430.014
columnar cuboidal epithelial cell differentiationGO:0002065820.014
ribonucleotide catabolic processGO:00092612080.014
response to insulinGO:00328681000.014
negative regulation of synaptic vesicle exocytosisGO:200030130.014
meiotic nuclear divisionGO:00071261150.014
apoptotic signaling pathwayGO:00971903060.014
organic hydroxy compound biosynthetic processGO:1901617770.014
peptide transportGO:00158331330.014
cellular response to epidermal growth factor stimulusGO:007136440.014
nuclear transportGO:00511691390.014
regulation of stress activated mapk cascadeGO:0032872690.014
regulation of cellular amino acid metabolic processGO:000652150.014
norepinephrine transportGO:001587420.014
peptidyl amino acid modificationGO:00181933360.014
positive regulation of protein modification processGO:00314012990.014
regulation of cell motilityGO:20001452360.014
metencephalon developmentGO:0022037890.013
neural precursor cell proliferationGO:00613511210.013
ribose phosphate biosynthetic processGO:0046390590.013
transmembrane transportGO:00550854120.013
regulation of acetylcholine secretion neurotransmissionGO:001405620.013
positive regulation of mapk cascadeGO:00434101700.013
acetylcholine secretion neurotransmissionGO:001405520.013
cytokine productionGO:00018163190.013
response to peptide hormoneGO:00434341270.013
neural tube formationGO:00018411080.013
cellular polysaccharide metabolic processGO:0044264380.013
response to growth factorGO:00708481980.013
response to light stimulusGO:00094161350.013
cellular nitrogen compound catabolic processGO:00442702800.013
regulation of cellular component biogenesisGO:00440871810.013
exocytosisGO:00068871210.013
photoreceptor cell maintenanceGO:0045494190.013
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.013
guanosine containing compound catabolic processGO:19010691440.013
cell growthGO:00160491300.013
tube formationGO:00351481400.013
tissue homeostasisGO:00018941150.013
appendage morphogenesisGO:00351071490.013
antimicrobial peptide biosynthetic processGO:000277720.013
urogenital system developmentGO:00016552610.013
protein glycosylationGO:0006486550.013
formation of organ boundaryGO:001016010.013
negative regulation of immune system processGO:00026832090.013
leukocyte homeostasisGO:0001776790.013
transition metal ion transportGO:0000041380.013
positive regulation of programmed cell deathGO:00430682180.012
regulation of apoptotic signaling pathwayGO:20012331970.012
developmental cell growthGO:0048588840.012
lymphocyte activation involved in immune responseGO:0002285930.012
liver developmentGO:0001889660.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
activation of immune responseGO:00022531380.012
intracellular mrna localizationGO:000829840.012
establishment of organelle localizationGO:00516561220.012
b cell differentiationGO:0030183780.012
organic hydroxy compound metabolic processGO:19016152030.012
protein importGO:00170381010.012
myotube differentiationGO:00149021050.012
actin filament polymerizationGO:0030041440.012
regulation of neuron projection developmentGO:00109751690.012
dephosphorylationGO:00163111290.012
mrna metabolic processGO:0016071840.012
negative regulation of epidermal growth factor activated receptor activityGO:000717530.012
regulation of body fluid levelsGO:00508781620.012
antimicrobial peptide productionGO:000277520.012
response to copper ionGO:004668830.012
ubiquitin dependent protein catabolic processGO:00065111290.012
nucleocytoplasmic transportGO:00069131390.012
actin polymerization or depolymerizationGO:0008154540.012
cellular carbohydrate metabolic processGO:00442621190.012
heart morphogenesisGO:00030071780.012
purine containing compound biosynthetic processGO:0072522700.012
purine ribonucleoside catabolic processGO:00461302050.012
regulation of membrane potentialGO:00423911920.012
blastocyst developmentGO:0001824800.011
maternal determination of anterior posterior axis embryoGO:000835820.011
extracellular structure organizationGO:00430621480.011
development of primary male sexual characteristicsGO:0046546880.011
purine nucleoside catabolic processGO:00061522050.011
regulation of muscle tissue developmentGO:1901861970.011
regulation of cell activationGO:00508652890.011
response to epidermal growth factorGO:007084940.011
organophosphate catabolic processGO:00464342320.011
cochlea developmentGO:0090102350.011
limb morphogenesisGO:00351081490.011
neural tube developmentGO:00219151600.011
stem cell proliferationGO:00720891170.011
regulation of antimicrobial humoral responseGO:000275930.011
cellular response to cytokine stimulusGO:00713451890.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
nucleoside triphosphate catabolic processGO:00091432050.011
cerebellar cortex developmentGO:0021695480.011
regulation of cardioblast differentiationGO:005189030.011
negative regulation of leukocyte differentiationGO:1902106510.011
anion transportGO:00068201770.011
regulation of inflammatory responseGO:00507271470.011
regulation of epithelial cell proliferationGO:00506781410.011
negative regulation of growthGO:0045926990.011
embryonic heart tube developmentGO:0035050650.011
ribonucleoside metabolic processGO:00091192450.011
ribonucleotide biosynthetic processGO:0009260590.011
regulation of lymphocyte differentiationGO:00456191070.011
regulation of cell cycle processGO:00105641600.011
cellular chemical homeostasisGO:00550822150.011
regulation of hormone secretionGO:0046883880.011
leukocyte migrationGO:00509001240.011
oocyte anterior posterior axis specificationGO:000731420.011
multicellular organismal agingGO:0010259240.011
female gamete generationGO:0007292740.011
mesenchymal cell developmentGO:0014031930.010
chromatin organizationGO:00063252060.010
neuromuscular processGO:0050905990.010
negative regulation of organelle organizationGO:0010639900.010
response to lipopolysaccharideGO:00324961280.010
embryonic skeletal system morphogenesisGO:0048704910.010
alpha beta t cell differentiationGO:0046632690.010
ribonucleoside catabolic processGO:00424542060.010
protein polymerizationGO:0051258570.010
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.010
glycosyl compound catabolic processGO:19016582060.010
neuroblast differentiationGO:001401620.010
regulation of rna export from nucleusGO:004683140.010
nucleobase containing compound transportGO:0015931270.010
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126740.010
purine nucleotide biosynthetic processGO:0006164650.010
protein targetingGO:00066051430.010
positive regulation of bindingGO:0051099490.010
inflammatory responseGO:00069542440.010
regulation of lamellipodium assemblyGO:001059130.010

Ercc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.036
nervous system diseaseDOID:86300.035
disease of anatomical entityDOID:700.035
inherited metabolic disorderDOID:65500.025
central nervous system diseaseDOID:33100.021
electroclinical syndromeDOID:005070100.015
brain diseaseDOID:93600.015
epilepsy syndromeDOID:182600.015
connective tissue diseaseDOID:6500.014
musculoskeletal system diseaseDOID:1700.014
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
cancerDOID:16200.013
bone diseaseDOID:008000100.012
neuropathyDOID:87000.011
bone remodeling diseaseDOID:008000500.010
osteopetrosisDOID:1353300.010
osteosclerosisDOID:425400.010