IMP: Integrative Multi-species Prediction

Mus musculus

14 known processes

Zscan4b

zinc finger and SCAN domain containing 4B

(Aliases: EG665780)

Ensembl: ENSMUSG00000091643
Entrez: 665780
UniProtKB: E9Q3G0

Process Predictions
Disease Predictions

Zscan4b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
chromatin organization	GO:0006325	206	0.227
dna metabolic process	GO:0006259	303	0.153
chromatin modification	GO:0016568	187	0.111
dna repair	GO:0006281	107	0.085
covalent chromatin modification	GO:0016569	163	0.071
regulation of chromatin silencing	GO:0031935	2	0.060
muscle cell differentiation	GO:0042692	261	0.060
cellular amino acid metabolic process	GO:0006520	103	0.059
stem cell differentiation	GO:0048863	268	0.055
mitotic recombination	GO:0006312	3	0.052
regulation of cellular ketone metabolic process	GO:0010565	66	0.049
cellular response to dna damage stimulus	GO:0006974	207	0.048
cellular ketone metabolic process	GO:0042180	84	0.047
gene silencing by mirna	GO:0035195	10	0.044
striated muscle tissue development	GO:0014706	293	0.044
regulation of cellular amino acid metabolic process	GO:0006521	5	0.043
muscle tissue development	GO:0060537	308	0.042
cell fate commitment	GO:0045165	210	0.040
histone modification	GO:0016570	159	0.040
peptidyl amino acid modification	GO:0018193	336	0.040
response to organonitrogen compound	GO:0010243	246	0.039
forebrain development	GO:0030900	302	0.038
peptidyl lysine modification	GO:0018205	77	0.038
dna recombination	GO:0006310	92	0.037
somatotropin secreting cell development	GO:0060133	2	0.037
double strand break repair	GO:0006302	48	0.036
regulation of cell cycle phase transition	GO:1901987	77	0.035
leukocyte mediated immunity	GO:0002443	174	0.035
camera type eye development	GO:0043010	266	0.034
digestive tract development	GO:0048565	190	0.034
chromatin assembly or disassembly	GO:0006333	16	0.032
ventricular compact myocardium morphogenesis	GO:0003223	2	0.031
maintenance of location	GO:0051235	89	0.031
myeloid cell differentiation	GO:0030099	233	0.031
cytoplasmic transport	GO:0016482	234	0.030
leukocyte differentiation	GO:0002521	342	0.030
stem cell development	GO:0048864	219	0.030
protein dna complex subunit organization	GO:0071824	28	0.029
central nervous system neuron differentiation	GO:0021953	162	0.029
regulation of myeloid cell differentiation	GO:0045637	96	0.029
regulation of defense response	GO:0031347	233	0.028
protein localization to organelle	GO:0033365	185	0.028
immune effector process	GO:0002252	321	0.027
cellular response to lipid	GO:0071396	145	0.027
regulation of leukocyte differentiation	GO:1902105	159	0.027
negative regulation of calcium ion dependent exocytosis	GO:0045955	3	0.027
negative regulation of cellular amine metabolic process	GO:0033239	1	0.026
amine metabolic process	GO:0009308	45	0.026
cellular response to organonitrogen compound	GO:0071417	145	0.026
ribose phosphate metabolic process	GO:0019693	291	0.026
gene silencing	GO:0016458	38	0.025
purine ribonucleotide metabolic process	GO:0009150	290	0.025
cellular response to acid chemical	GO:0071229	68	0.024
posttranscriptional regulation of gene expression	GO:0010608	155	0.024
dendrite development	GO:0016358	115	0.024
macromolecule catabolic process	GO:0009057	281	0.024
pigmentation	GO:0043473	71	0.024
carbohydrate metabolic process	GO:0005975	230	0.024
response to light stimulus	GO:0009416	135	0.023
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.023
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.023
mrna transcription from rna polymerase ii promoter	GO:0042789	4	0.023
response to radiation	GO:0009314	165	0.023
lymphocyte mediated immunity	GO:0002449	139	0.023
myeloid leukocyte differentiation	GO:0002573	119	0.023
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.022
homeostasis of number of cells	GO:0048872	210	0.022
positive regulation of protein transport	GO:0051222	93	0.022
cell type specific apoptotic process	GO:0097285	268	0.022
male gamete generation	GO:0048232	285	0.022
stem cell maintenance	GO:0019827	130	0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.022
axonogenesis	GO:0007409	274	0.022
regulation of cellular amine metabolic process	GO:0033238	20	0.022
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.022
adaptive immune response	GO:0002250	155	0.022
response to acid chemical	GO:0001101	111	0.021
regulation of inflammatory response	GO:0050727	147	0.021
negative regulation of cellular component organization	GO:0051129	194	0.021
protein maturation	GO:0051604	176	0.021
regulation of secretion	GO:0051046	274	0.021
endocytosis	GO:0006897	168	0.021
negative regulation of cell cycle phase transition	GO:1901988	48	0.021
endomembrane system organization	GO:0010256	147	0.020
negative regulation of protein metabolic process	GO:0051248	282	0.020
oxidation reduction process	GO:0055114	342	0.020
hematopoietic progenitor cell differentiation	GO:0002244	143	0.020
methylation	GO:0032259	134	0.020
spermatogenesis	GO:0007283	284	0.020
intracellular protein transport	GO:0006886	204	0.020
response to peptide	GO:1901652	136	0.020
gliogenesis	GO:0042063	141	0.019
blood vessel morphogenesis	GO:0048514	285	0.019
ribonucleotide metabolic process	GO:0009259	291	0.019
neuron death	GO:0070997	154	0.019
ribonucleoside metabolic process	GO:0009119	245	0.019
nucleoside triphosphate catabolic process	GO:0009143	205	0.019
nucleotide catabolic process	GO:0009166	217	0.019
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.019
cellular chemical homeostasis	GO:0055082	215	0.019
regulation of membrane potential	GO:0042391	192	0.018
inflammatory response	GO:0006954	244	0.018
nucleoside phosphate metabolic process	GO:0006753	338	0.018
positive regulation of leukocyte differentiation	GO:1902107	86	0.018
response to organic cyclic compound	GO:0014070	198	0.018
regulation of hormone levels	GO:0010817	211	0.018
positive regulation of intracellular transport	GO:0032388	70	0.018
action potential	GO:0001508	78	0.018
regulation of cell projection organization	GO:0031344	206	0.018
positive regulation of cellular amine metabolic process	GO:0033240	5	0.018
regulation of protein maturation	GO:1903317	96	0.018
regulation of response to wounding	GO:1903034	189	0.018
negative regulation of cell proliferation	GO:0008285	296	0.018
multicellular organismal signaling	GO:0035637	91	0.017
ossification	GO:0001503	216	0.017
anatomical structure homeostasis	GO:0060249	145	0.017
purine nucleotide metabolic process	GO:0006163	302	0.017
sensory perception	GO:0007600	245	0.017
response to lipopolysaccharide	GO:0032496	128	0.017
regulation of dna recombination	GO:0000018	34	0.017
neuron apoptotic process	GO:0051402	142	0.017
germ cell development	GO:0007281	185	0.017
posttranscriptional gene silencing by rna	GO:0035194	10	0.017
negative regulation of mitotic cell cycle phase transition	GO:1901991	45	0.016
lipid biosynthetic process	GO:0008610	179	0.016
locomotory behavior	GO:0007626	195	0.016
cellular amine metabolic process	GO:0044106	44	0.016
purine nucleoside catabolic process	GO:0006152	205	0.016
positive regulation of nervous system development	GO:0051962	221	0.016
metanephric thick ascending limb development	GO:0072233	2	0.016
exocytosis	GO:0006887	121	0.016
protein targeting	GO:0006605	143	0.016
chemotaxis	GO:0006935	247	0.016
response to molecule of bacterial origin	GO:0002237	143	0.016
aromatic compound catabolic process	GO:0019439	286	0.016
regulation of cytokine production	GO:0001817	266	0.016
cellular macromolecule catabolic process	GO:0044265	206	0.016
cellular response to lipopolysaccharide	GO:0071222	77	0.016
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.016
mitotic cell cycle	GO:0000278	195	0.016
cation homeostasis	GO:0055080	212	0.016
osteoclast differentiation	GO:0030316	62	0.016
dna packaging	GO:0006323	30	0.015
immunoglobulin mediated immune response	GO:0016064	69	0.015
regulation of secretion by cell	GO:1903530	249	0.015
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.015
sulfur compound metabolic process	GO:0006790	100	0.015
carbohydrate homeostasis	GO:0033500	128	0.015
lipid localization	GO:0010876	126	0.015
organophosphate catabolic process	GO:0046434	232	0.015
positive regulation of cellular component biogenesis	GO:0044089	94	0.015
mapk cascade	GO:0000165	281	0.015
regulation of cell activation	GO:0050865	289	0.015
regulation of organelle organization	GO:0033043	289	0.015
gland development	GO:0048732	330	0.014
digestive system development	GO:0055123	200	0.014
regulation of neuron apoptotic process	GO:0043523	122	0.014
spermatid development	GO:0007286	108	0.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.014
membrane organization	GO:0061024	245	0.014
skin development	GO:0043588	220	0.014
neuronal action potential	GO:0019228	54	0.014
b cell mediated immunity	GO:0019724	71	0.014
carbohydrate biosynthetic process	GO:0016051	74	0.014
regulation of cell cycle process	GO:0010564	160	0.014
dna conformation change	GO:0071103	37	0.014
fertilization	GO:0009566	127	0.014
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.014
positive regulation of cell development	GO:0010720	237	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
developmental maturation	GO:0021700	193	0.014
fat cell differentiation	GO:0045444	160	0.014
response to amino acid	GO:0043200	37	0.014
positive regulation of secretion	GO:0051047	130	0.014
regulation of intracellular transport	GO:0032386	159	0.014
reactive oxygen species metabolic process	GO:0072593	84	0.014
cellular homeostasis	GO:0019725	240	0.014
nucleoside phosphate catabolic process	GO:1901292	222	0.014
muscle cell development	GO:0055001	133	0.014
cytokine production	GO:0001816	319	0.014
regulation of neuron death	GO:1901214	134	0.013
peptidyl lysine acetylation	GO:0018394	45	0.013
multicellular organismal homeostasis	GO:0048871	164	0.013
multicellular organism growth	GO:0035264	161	0.013
glial cell differentiation	GO:0010001	131	0.013
regulation of mapk cascade	GO:0043408	248	0.013
defense response to other organism	GO:0098542	197	0.013
positive regulation of cytokine production	GO:0001819	174	0.013
nucleobase containing small molecule metabolic process	GO:0055086	352	0.013
chromatin remodeling	GO:0006338	32	0.013
dna alkylation	GO:0006305	43	0.013
response to ionizing radiation	GO:0010212	42	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013
posttranscriptional gene silencing	GO:0016441	10	0.013
meiosis i	GO:0007127	60	0.013
protein localization to nucleus	GO:0034504	121	0.013
nitrogen compound transport	GO:0071705	271	0.013
protein acylation	GO:0043543	64	0.013
negative regulation of proteolysis	GO:0045861	74	0.013
dna modification	GO:0006304	50	0.013
mesenchyme development	GO:0060485	152	0.013
cellular carbohydrate metabolic process	GO:0044262	119	0.013
alcohol metabolic process	GO:0006066	116	0.013
vesicle organization	GO:0016050	60	0.013
skeletal muscle organ development	GO:0060538	163	0.013
nucleoside monophosphate metabolic process	GO:0009123	85	0.013
extracellular structure organization	GO:0043062	148	0.012
t cell activation	GO:0042110	289	0.012
gene silencing by rna	GO:0031047	19	0.012
negative regulation of mitotic cell cycle	GO:0045930	58	0.012
internal protein amino acid acetylation	GO:0006475	42	0.012
regulation of establishment of protein localization	GO:0070201	181	0.012
single organism nuclear import	GO:1902593	95	0.012
regulation of t cell activation	GO:0050863	170	0.012
innate immune response	GO:0045087	157	0.012
nucleoside metabolic process	GO:0009116	246	0.012
cognition	GO:0050890	149	0.012
proteasomal protein catabolic process	GO:0010498	98	0.012
single fertilization	GO:0007338	82	0.012
regulation of myeloid leukocyte differentiation	GO:0002761	58	0.012
protein catabolic process	GO:0030163	221	0.012
respiratory tube development	GO:0030323	167	0.012
cellular response to cytokine stimulus	GO:0071345	189	0.012
transmembrane transport	GO:0055085	412	0.012
regulation of proteolysis	GO:0030162	164	0.012
carbohydrate derivative catabolic process	GO:1901136	231	0.012
myeloid cell homeostasis	GO:0002262	114	0.012
negative regulation of dna recombination	GO:0045910	13	0.012
positive regulation of growth	GO:0045927	104	0.012
regulation of inositol trisphosphate biosynthetic process	GO:0032960	3	0.012
negative regulation of neuron apoptotic process	GO:0043524	92	0.012
urogenital system development	GO:0001655	261	0.012
canonical wnt signaling pathway	GO:0060070	130	0.012
regulation of gene silencing by rna	GO:0060966	5	0.012
positive regulation of protein modification process	GO:0031401	299	0.012
positive regulation of cell activation	GO:0050867	158	0.012
cellular response to hexose stimulus	GO:0071331	47	0.012
multi multicellular organism process	GO:0044706	109	0.012
cellular nitrogen compound catabolic process	GO:0044270	280	0.012
organonitrogen compound catabolic process	GO:1901565	264	0.012
establishment of protein localization to organelle	GO:0072594	118	0.012
regulation of intracellular protein transport	GO:0033157	82	0.012
protein import	GO:0017038	101	0.012
nephron epithelium development	GO:0072009	92	0.012
g protein coupled receptor signaling pathway	GO:0007186	243	0.012
cellular lipid metabolic process	GO:0044255	323	0.012
purine ribonucleoside metabolic process	GO:0046128	241	0.012
negative regulation of intracellular signal transduction	GO:1902532	167	0.012
protein processing	GO:0016485	163	0.012
organic hydroxy compound metabolic process	GO:1901615	203	0.012
response to temperature stimulus	GO:0009266	55	0.012
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.012
striated muscle cell development	GO:0055002	125	0.012
immunoglobulin production	GO:0002377	73	0.012
negative regulation of cell cycle	GO:0045786	123	0.012
organelle fission	GO:0048285	170	0.011
negative regulation of organelle organization	GO:0010639	90	0.011
regulation of cytoplasmic transport	GO:1903649	112	0.011
cellular response to hormone stimulus	GO:0032870	150	0.011
cellular protein catabolic process	GO:0044257	155	0.011
nuclear transport	GO:0051169	139	0.011
histone acetylation	GO:0016573	41	0.011
nucleotide metabolic process	GO:0009117	332	0.011
nucleocytoplasmic transport	GO:0006913	139	0.011
placenta development	GO:0001890	140	0.011
regulation of protein catabolic process	GO:0042176	108	0.011
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.011
leukocyte activation involved in immune response	GO:0002366	126	0.011
nuclear dna replication	GO:0033260	3	0.011
reactive nitrogen species metabolic process	GO:2001057	0	0.011
intrinsic apoptotic signaling pathway	GO:0097193	132	0.011
response to peptide hormone	GO:0043434	127	0.011
purine ribonucleoside catabolic process	GO:0046130	205	0.011
appendage development	GO:0048736	166	0.011
sensory perception of sound	GO:0007605	97	0.011
cellular response to molecule of bacterial origin	GO:0071219	83	0.011
organic cyclic compound catabolic process	GO:1901361	295	0.011
double strand break repair via homologous recombination	GO:0000724	21	0.011
regulation of lymphocyte activation	GO:0051249	240	0.011
regulation of muscle tissue development	GO:1901861	97	0.011
transmission of nerve impulse	GO:0019226	76	0.011
reactive oxygen species biosynthetic process	GO:1903409	8	0.011
negative regulation of protein maturation	GO:1903318	79	0.011
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.011
smoothened signaling pathway	GO:0007224	105	0.011
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.011
cell cycle g1 s phase transition	GO:0044843	57	0.011
atp metabolic process	GO:0046034	75	0.011
negative regulation of immune system process	GO:0002683	209	0.011
regulation of osteoclast differentiation	GO:0045670	36	0.011
negative regulation of cellular protein metabolic process	GO:0032269	247	0.011
respiratory system development	GO:0060541	190	0.011
positive regulation of protein phosphorylation	GO:0001934	242	0.011
cellular ion homeostasis	GO:0006873	165	0.011
regulation of g1 s transition of mitotic cell cycle	GO:2000045	35	0.011
negative regulation of gene expression epigenetic	GO:0045814	15	0.011
learning or memory	GO:0007611	148	0.011
microtubule based process	GO:0007017	236	0.011
regulation of homeostatic process	GO:0032844	182	0.011
regulation of leukocyte mediated immunity	GO:0002703	104	0.011
cellular response to organic cyclic compound	GO:0071407	87	0.011
cation transport	GO:0006812	399	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.011
negative regulation of neuron death	GO:1901215	98	0.011
regulation of neuron projection development	GO:0010975	169	0.010
ectodermal cell differentiation	GO:0010668	3	0.010
interferon gamma production	GO:0032609	67	0.010
protein kinase b signaling	GO:0043491	74	0.010
tissue remodeling	GO:0048771	102	0.010
compound eye development	GO:0048749	1	0.010
kidney development	GO:0001822	213	0.010
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.010
regulation of protein localization	GO:0032880	231	0.010
negative regulation of cell activation	GO:0050866	111	0.010
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.010
regulation of protein processing	GO:0070613	96	0.010
dna methylation	GO:0006306	43	0.010
ear development	GO:0043583	200	0.010
glycosyl compound catabolic process	GO:1901658	206	0.010
cell maturation	GO:0048469	127	0.010
cellular response to biotic stimulus	GO:0071216	92	0.010
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.010
inorganic ion transmembrane transport	GO:0098660	234	0.010
lymphocyte differentiation	GO:0030098	242	0.010
organonitrogen compound biosynthetic process	GO:1901566	192	0.010
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.010
ameboidal type cell migration	GO:0001667	128	0.010
regulation of protein transport	GO:0051223	163	0.010
calcium ion homeostasis	GO:0055074	127	0.010

Zscan4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.028
disease of anatomical entity	DOID:7	0.028
sensory system disease	DOID:0050155	0.019
eye and adnexa disease	DOID:1492	0.019
disease of cellular proliferation	DOID:14566	0.015
cancer	DOID:162	0.015
organ system cancer	DOID:0050686	0.015
eye disease	DOID:5614	0.010

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