Mus musculus

0 known processes

Hgs

HGF-regulated tyrosine kinase substrate

(Aliases: ZFYVE8,Hgr,Hrs)

Hgs biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugationGO:00324461870.359
Fly
ras protein signal transductionGO:0007265770.331
response to peptide hormoneGO:00434341270.202
olfactory learningGO:000835520.153
compound eye developmentGO:004874910.143
negative regulation of protein metabolic processGO:00512482820.120
Fly
oocyte constructionGO:000730820.117
oocyte axis specificationGO:000730920.106
protein modification by small protein conjugation or removalGO:00706472070.098
Fly
cellular response to peptideGO:1901653920.097
cellular protein catabolic processGO:00442571550.092
cellular homeostasisGO:00197252400.089
microtubule cytoskeleton organizationGO:00002261570.088
protein ubiquitinationGO:00165671710.087
Fly
macromolecule catabolic processGO:00090572810.087
negative regulation of intracellular signal transductionGO:19025321670.086
Human
oxidation reduction processGO:00551143420.085
regulation of cell cycleGO:00517262810.083
Fly
positive regulation of protein modification processGO:00314012990.080
Fly
stem cell differentiationGO:00488632680.074
respiratory system developmentGO:00605411900.069
Fly
fatty acid metabolic processGO:00066311210.069
response to peptideGO:19016521360.068
macromolecule methylationGO:00434141200.067
cellular response to organonitrogen compoundGO:00714171450.064
cation transportGO:00068123990.064
synaptic vesicle membrane organizationGO:004849910.064
adherens junction maintenanceGO:003433410.062
cellular chemical homeostasisGO:00550822150.057
apoptotic signaling pathwayGO:00971903060.056
regulation of cardioblast differentiationGO:005189030.055
small gtpase mediated signal transductionGO:0007264970.054
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.054
vesicle organizationGO:0016050600.052
cell fate commitmentGO:00451652100.051
protein catabolic processGO:00301632210.051
positive regulation of cellular protein catabolic processGO:1903364340.050
cytoplasmic transportGO:00164822340.050
Human
cilium morphogenesisGO:00602711020.049
cellular response to insulin stimulusGO:0032869780.048
purine nucleotide metabolic processGO:00061633020.047
regulation of histone h3 k27 methylationGO:006108560.047
regionalizationGO:00030023370.046
response to insulinGO:00328681000.046
cellularizationGO:000734910.046
cellular ketone metabolic processGO:0042180840.045
chromatin organizationGO:00063252060.045
modification dependent macromolecule catabolic processGO:00436321330.042
purine ribonucleotide catabolic processGO:00091542080.041
sensory system developmentGO:004888030.040
dna metabolic processGO:00062593030.040
negative regulation of dendritic spine morphogenesisGO:006100230.038
sodium ion transmembrane transportGO:0035725490.037
mrna transportGO:0051028130.037
rna localizationGO:0006403230.037
negative regulation of phosphate metabolic processGO:00459361840.037
Fly
carbohydrate metabolic processGO:00059752300.037
germ cell developmentGO:00072811850.036
Fly
cellular response to hormone stimulusGO:00328701500.035
regulation of mapk cascadeGO:00434082480.035
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.034
Fly
actin cytoskeleton organizationGO:00300362200.034
retrograde transport endosome to golgiGO:004214720.033
protein localization to organelleGO:00333651850.033
Human
mapk cascadeGO:00001652810.033
activation of jnkk activityGO:000725630.033
negative regulation of phosphorylationGO:00423261660.032
Fly
response to organonitrogen compoundGO:00102432460.032
oocyte anterior posterior axis specificationGO:000731420.031
ribose phosphate metabolic processGO:00196932910.031
microtubule based processGO:00070172360.029
regulation of cellular amine metabolic processGO:0033238200.029
positive regulation of homeostatic processGO:0032846640.029
regulation of cellular ketone metabolic processGO:0010565660.029
intracellular mrna localizationGO:000829840.029
aromatic compound catabolic processGO:00194392860.028
extracellular structure organizationGO:00430621480.028
negative regulation of immune system processGO:00026832090.028
defecationGO:003042110.028
development of primary sexual characteristicsGO:00451371430.028
positive regulation of transferase activityGO:00513471670.027
maternal determination of anterior posterior axis embryoGO:000835820.027
protein localization to plasma membraneGO:0072659570.027
cell cycle switchingGO:006018410.027
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.026
mitotic cell cycleGO:00002781950.026
establishment or maintenance of cell polarityGO:0007163860.025
asymmetric stem cell divisionGO:009872230.025
regulation of rna export from nucleusGO:004683140.025
regulation of fatty acid biosynthetic processGO:0042304120.025
ion transmembrane transportGO:00342203610.025
cellular nitrogen compound catabolic processGO:00442702800.025
ribonucleoprotein complex disassemblyGO:003298830.024
inorganic cation transmembrane transportGO:00986622070.024
negative regulation of triglyceride metabolic processGO:009020940.024
glycoprotein metabolic processGO:00091001160.024
ectodermal cell differentiationGO:001066830.024
cilium assemblyGO:0042384810.023
establishment of protein localization to membraneGO:0090150540.023
cellular amine metabolic processGO:0044106440.023
negative regulation of cell cycleGO:00457861230.023
leukocyte apoptotic processGO:0071887710.023
rab protein signal transductionGO:003248210.023
methylationGO:00322591340.023
plasma membrane organizationGO:0007009900.023
cellular response to peptide hormone stimulusGO:0071375920.023
regulation of protein bindingGO:0043393600.022
histone lysine methylationGO:0034968500.022
positive regulation of protein phosphorylationGO:00019342420.022
locomotory behaviorGO:00076261950.022
transmembrane transportGO:00550854120.022
positive regulation of necrotic cell deathGO:001094010.022
regulation of kinase activityGO:00435492490.021
regulation of transferase activityGO:00513382630.021
organic cyclic compound catabolic processGO:19013612950.021
cardiac cell fate specificationGO:006091220.021
regulation of protein catabolic processGO:00421761080.021
nucleic acid transportGO:0050657180.021
negative regulation of molecular functionGO:00440922580.021
negative regulation of cell fate specificationGO:000999640.021
nucleobase containing small molecule metabolic processGO:00550863520.021
neural precursor cell proliferationGO:00613511210.021
carbohydrate derivative biosynthetic processGO:19011371830.020
establishment of rna localizationGO:0051236180.020
purine containing compound metabolic processGO:00725213110.020
cellular response to extracellular stimulusGO:0031668810.020
nuclear transportGO:00511691390.020
nucleotide catabolic processGO:00091662170.020
negative regulation of protein modification processGO:00314001630.020
Fly
positive regulation of histone h3 k27 methylationGO:006108740.020
positive regulation of purine nucleotide metabolic processGO:19005441140.020
multicellular organism growthGO:00352641610.019
purine nucleotide catabolic processGO:00061952110.019
erbb signaling pathwayGO:0038127320.019
Fly
calcium ion transportGO:00068161590.019
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.019
polysaccharide biosynthetic processGO:0000271200.019
regulation of stem cell differentiationGO:2000736500.019
lateral line system developmentGO:004892510.019
cell divisionGO:00513011200.019
regulation of proteolysisGO:00301621640.018
regulation of lymphocyte anergyGO:000291140.018
epidermal growth factor receptor signaling pathwayGO:0007173280.018
Fly
ribonucleoside metabolic processGO:00091192450.018
carbohydrate derivative catabolic processGO:19011362310.018
engulfment of apoptotic cellGO:004365230.018
maintenance of locationGO:0051235890.018
clathrin coat assemblyGO:004826820.018
regulation of intracellular transportGO:00323861590.017
protein alkylationGO:0008213810.017
positive regulation of protein catabolic processGO:0045732600.017
oocyte developmentGO:0048599330.017
regulation of homeostatic processGO:00328441820.017
modification by symbiont of host morphology or physiologyGO:004400340.017
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.017
positive regulation of proteolysisGO:0045862850.017
gtp catabolic processGO:00061841430.017
cation transmembrane transportGO:00986552660.017
chromatin modificationGO:00165681870.017
extracellular matrix organizationGO:00301981470.017
sensory perceptionGO:00076002450.016
negative regulation of protein processingGO:0010955790.016
regulation of lymphocyte differentiationGO:00456191070.016
heterocycle catabolic processGO:00467002800.016
regulation of histone methylationGO:0031060300.016
epithelial cell developmentGO:00020641590.016
Fly
nucleobase containing compound transportGO:0015931270.016
negative regulation of cellular protein metabolic processGO:00322692470.016
Fly
notch signaling pathwayGO:0007219710.016
Fly
segmentationGO:0035282930.016
regulation of cellular amino acid metabolic processGO:000652150.016
establishment of protein localization to plasma membraneGO:0090002340.016
positive regulation of protein kinase activityGO:00458601440.016
regulation of lymphocyte activationGO:00512492400.016
behavioral response to nutrientGO:005178010.016
negative regulation of insulin receptor signaling pathwayGO:0046627140.016
cell cycle switching mitotic to meiotic cell cycleGO:005172810.016
sperm individualizationGO:000729110.015
cellular response to cytokine stimulusGO:00713451890.015
positive regulation of notch signaling pathwayGO:0045747180.015
regulation of leukocyte differentiationGO:19021051590.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.015
cell junction maintenanceGO:003433140.015
cellular response to dna damage stimulusGO:00069742070.015
spermatid developmentGO:00072861080.015
translationGO:0006412930.015
regulation of carbohydrate biosynthetic processGO:0043255400.014
myeloid leukocyte differentiationGO:00025731190.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
posttranslational protein targeting to membraneGO:000662020.014
regulation of cytoplasmic transportGO:19036491120.014
regulation of bindingGO:00510981110.014
membrane tubulationGO:009732040.014
modification dependent protein catabolic processGO:00199411330.014
glycoprotein biosynthetic processGO:0009101890.014
protein localization to membraneGO:00726571080.014
Human
oocyte differentiationGO:0009994350.014
regulation of cytoplasmic translationGO:200076540.014
stem cell developmentGO:00488642190.014
t cell differentiation in thymusGO:0033077770.014
organelle assemblyGO:00709251770.014
t cell activationGO:00421102890.014
positive regulation of cellular catabolic processGO:00313311480.013
learningGO:0007612980.013
regulation of jak stat cascadeGO:0046425340.013
Human
regulation of cardiac cell fate specificationGO:200004310.013
cerebellar granule cell precursor tangential migrationGO:002193510.013
transition metal ion transportGO:0000041380.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
anion transportGO:00068201770.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.013
circadian rhythmGO:00076231140.013
positive regulation of bindingGO:0051099490.013
histone methylationGO:0016571710.013
establishment or maintenance of cytoskeleton polarityGO:003095220.013
response to nutrient levelsGO:00316671090.013
positive regulation of membrane protein ectodomain proteolysisGO:005104430.012
cellular lipid metabolic processGO:00442553230.012
protein methylationGO:0006479810.012
negative regulation of cell activationGO:00508661110.012
satellite cell activation involved in skeletal muscle regenerationGO:001490130.012
nuclear transcribed mrna catabolic processGO:0000956160.012
mesodermal cell migrationGO:000807840.012
mitotic cell cycle processGO:19030471590.012
glycosyl compound catabolic processGO:19016582060.012
male gamete generationGO:00482322850.012
fatty acid biosynthetic processGO:0006633410.012
protein maturationGO:00516041760.012
ribonucleotide metabolic processGO:00092592910.012
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.012
rhythmic processGO:00485111740.012
negative regulation of mapk cascadeGO:0043409650.012
cognitionGO:00508901490.012
fibroblast growth factor receptor signaling pathwayGO:0008543460.012
Fly
regulation of translationGO:0006417710.012
positive regulation of cell activationGO:00508671580.012
negative regulation of proteolysisGO:0045861740.012
nitrogen compound transportGO:00717052710.011
divalent inorganic cation transportGO:00725111780.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
posttranscriptional regulation of gene expressionGO:00106081550.011
mrna transcription from rna polymerase ii promoterGO:004278940.011
striated muscle tissue developmentGO:00147062930.011
ephrin receptor signaling pathwayGO:0048013200.011
organic anion transportGO:00157111370.011
mitotic cytokinesisGO:000028140.011
negative regulation of phosphorus metabolic processGO:00105631840.011
Fly
antimicrobial peptide productionGO:000277520.011
ribonucleotide catabolic processGO:00092612080.011
fat cell differentiationGO:00454441600.011
small molecule biosynthetic processGO:00442831320.011
brain segmentationGO:003528430.011
regulation of t cell activationGO:00508631700.011
cell type specific apoptotic processGO:00972852680.011
mrna metabolic processGO:0016071840.011
nucleotide metabolic processGO:00091173320.011
gonad developmentGO:00084061410.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
negative regulation of cellular component organizationGO:00511291940.011
protein processingGO:00164851630.011
circadian temperature homeostasisGO:006008620.011
negative regulation of triglyceride biosynthetic processGO:001086820.011
learning or memoryGO:00076111480.011
purine nucleoside metabolic processGO:00422782410.011
negative regulation of epidermal growth factor receptor signaling pathwayGO:004205960.010
Fly
cellular response to starvationGO:0009267570.010
carbohydrate transportGO:0008643620.010
nucleoside phosphate metabolic processGO:00067533380.010
regulation of chromatin modificationGO:1903308570.010
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.010
regulation of apoptotic signaling pathwayGO:20012331970.010
glucose metabolic processGO:0006006920.010
regulation of secretionGO:00510462740.010
Human
positive regulation of ran gtpase activityGO:003285330.010
regulation of membrane protein ectodomain proteolysisGO:005104330.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
insulin receptor signaling pathwayGO:0008286490.010
leukocyte proliferationGO:00706611720.010
early endosome to late endosome transportGO:004502220.010
purine ribonucleoside metabolic processGO:00461282410.010

Hgs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular diseaseDOID:008000000.044
musculoskeletal system diseaseDOID:1700.044
disease of anatomical entityDOID:700.044
nervous system diseaseDOID:86300.031
neuropathyDOID:87000.031
muscle tissue diseaseDOID:6600.026
myopathyDOID:42300.026
neuromuscular diseaseDOID:44000.026
charcot marie tooth diseaseDOID:1059500.016
bone diseaseDOID:008000100.013
osteopetrosisDOID:1353300.013
bone remodeling diseaseDOID:008000500.013
osteosclerosisDOID:425400.013
connective tissue diseaseDOID:6500.013