| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.787 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.645 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.621 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.501 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.446 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.416 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.378 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.376 | |
| organelle localization | GO:0051640 | 179 | 0.347 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.334 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.328 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.327 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.326 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.312 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.311 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.297 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.294 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.288 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.284 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.284 | |
| protein neddylation | GO:0045116 | 1 | 0.273 | Yeast Worm |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.270 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.269 | Yeast Worm |
| cellularization | GO:0007349 | 1 | 0.262 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.252 | |
| synaptic transmission | GO:0007268 | 329 | 0.249 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.246 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.221 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.219 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.217 | |
| gtp metabolic process | GO:0046039 | 144 | 0.216 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.213 | |
| gtp catabolic process | GO:0006184 | 143 | 0.195 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.193 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.192 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.191 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.190 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.189 | |
| protein catabolic process | GO:0030163 | 221 | 0.184 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.181 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.178 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.167 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.165 | |
| dna metabolic process | GO:0006259 | 303 | 0.163 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.153 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.151 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.148 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 2 | 0.141 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.141 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.140 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.128 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.128 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.126 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.120 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.114 | |
| germ cell development | GO:0007281 | 185 | 0.111 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.111 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.111 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.102 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.100 | |
| cell division | GO:0051301 | 120 | 0.095 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.095 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.093 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.093 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.089 | |
| regulation of mitochondrial fission | GO:0090140 | 3 | 0.085 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.081 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.077 | |
| intra golgi vesicle mediated transport | GO:0006891 | 1 | 0.076 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.076 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.075 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.074 | |
| male gamete generation | GO:0048232 | 285 | 0.074 | |
| spermatid differentiation | GO:0048515 | 115 | 0.074 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.072 | |
| cytokinesis | GO:0000910 | 17 | 0.071 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.063 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.062 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.062 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.060 | |
| spermatid development | GO:0007286 | 108 | 0.058 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.056 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.053 | |
| axonogenesis | GO:0007409 | 274 | 0.053 | |
| regulation of protein localization | GO:0032880 | 231 | 0.051 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.047 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.047 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.045 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.045 | |
| protein localization to organelle | GO:0033365 | 185 | 0.044 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.044 | Yeast Worm |
| metaphase plate congression | GO:0051310 | 2 | 0.043 | |
| cell growth | GO:0016049 | 130 | 0.042 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.042 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.041 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.040 | |
| regulation of long term synaptic potentiation | GO:1900271 | 4 | 0.039 | |
| regulation of cell migration | GO:0030334 | 219 | 0.037 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.037 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.036 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.035 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.035 | |
| proteasome assembly | GO:0043248 | 1 | 0.035 | |
| regulation of cell motility | GO:2000145 | 236 | 0.035 | |
| dna templated transcription elongation | GO:0006354 | 13 | 0.034 | |
| stem cell differentiation | GO:0048863 | 268 | 0.034 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.033 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.032 | |
| neuron projection guidance | GO:0097485 | 141 | 0.031 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.031 | |
| regulation of cell size | GO:0008361 | 72 | 0.030 | |
| membrane fusion | GO:0061025 | 38 | 0.030 | |
| synapse organization | GO:0050808 | 125 | 0.029 | |
| regulation of secretion | GO:0051046 | 274 | 0.028 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.027 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.027 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.026 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.026 | |
| exocytosis | GO:0006887 | 121 | 0.025 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.025 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.025 | |
| regulation of protein transport | GO:0051223 | 163 | 0.025 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.024 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.024 | |
| endomembrane system organization | GO:0010256 | 147 | 0.024 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.024 | |
| vesicle localization | GO:0051648 | 86 | 0.023 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 31 | 0.023 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.023 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.023 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.023 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.023 | |
| chromatin modification | GO:0016568 | 187 | 0.023 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.022 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.022 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.021 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.021 | |
| chromatin organization | GO:0006325 | 206 | 0.021 | |
| spermatogenesis | GO:0007283 | 284 | 0.020 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.020 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.020 | |
| lipid localization | GO:0010876 | 126 | 0.020 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.020 | |
| membrane organization | GO:0061024 | 245 | 0.020 | |
| microtubule based process | GO:0007017 | 236 | 0.020 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.019 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.019 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.019 | |
| developmental cell growth | GO:0048588 | 84 | 0.019 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.019 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.018 | |
| positive regulation of oxidative stress induced cell death | GO:1903209 | 6 | 0.018 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.018 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.018 | |
| golgi vesicle transport | GO:0048193 | 30 | 0.018 | |
| chromosome segregation | GO:0007059 | 48 | 0.018 | |
| regionalization | GO:0003002 | 337 | 0.018 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.017 | |
| macromolecular complex disassembly | GO:0032984 | 43 | 0.017 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.017 | |
| response to light stimulus | GO:0009416 | 135 | 0.017 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.017 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.017 | |
| transmembrane transport | GO:0055085 | 412 | 0.017 | |
| body morphogenesis | GO:0010171 | 45 | 0.017 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.016 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.016 | |
| mitochondrion organization | GO:0007005 | 134 | 0.016 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.016 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.016 | |
| neuron neuron synaptic transmission | GO:0007270 | 69 | 0.015 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.015 | |
| regulation of cell shape | GO:0008360 | 39 | 0.015 | |
| intracellular protein transport | GO:0006886 | 204 | 0.015 | |
| endoplasmic reticulum organization | GO:0007029 | 10 | 0.015 | |
| isg15 protein conjugation | GO:0032020 | 4 | 0.015 | |
| mitochondrion distribution | GO:0048311 | 4 | 0.015 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.015 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.015 | |
| cell adhesion | GO:0007155 | 329 | 0.015 | |
| telencephalon development | GO:0021537 | 186 | 0.015 | |
| protein ubiquitination | GO:0016567 | 171 | 0.015 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.015 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.015 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.015 | |
| organelle fission | GO:0048285 | 170 | 0.015 | |
| histone modification | GO:0016570 | 159 | 0.014 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.014 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.014 | |
| positive regulation of mitochondrial fission | GO:0090141 | 2 | 0.014 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.014 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.014 | |
| dna repair | GO:0006281 | 107 | 0.014 | |
| protein targeting | GO:0006605 | 143 | 0.014 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.013 | |
| regulation of cell growth | GO:0001558 | 91 | 0.013 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.013 | |
| maintenance of location | GO:0051235 | 89 | 0.013 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.013 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.013 | |
| nucleus localization | GO:0051647 | 20 | 0.013 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.013 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.013 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.012 | |
| cell maturation | GO:0048469 | 127 | 0.012 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.012 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.012 | |
| learning or memory | GO:0007611 | 148 | 0.012 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.012 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.012 | |
| vesicle organization | GO:0016050 | 60 | 0.012 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.012 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.012 | |
| forebrain development | GO:0030900 | 302 | 0.012 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.012 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.012 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.012 | |
| skeletal muscle cell differentiation | GO:0035914 | 66 | 0.011 | |
| regulation of transcription elongation from rna polymerase ii promoter | GO:0034243 | 9 | 0.011 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.011 | |
| response to growth factor | GO:0070848 | 198 | 0.011 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.011 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.011 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.011 | |
| negative regulation of cell motility | GO:2000146 | 61 | 0.011 | |
| neuron migration | GO:0001764 | 122 | 0.011 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.011 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.011 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.011 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.011 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.010 | |
| neurotransmitter transport | GO:0006836 | 76 | 0.010 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.010 | |
| regulation of translation | GO:0006417 | 71 | 0.010 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.010 | |
| gonad development | GO:0008406 | 141 | 0.010 | |
