Mus musculus

16 known processes

Uba1

ubiquitin-like modifier activating enzyme 1

(Aliases: Ube1x,A1S9,AA989744,Ube-1,Sbx)

Uba1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.090
cytoplasmic transportGO:00164822340.076
nucleobase containing small molecule metabolic processGO:00550863520.075
endocytosisGO:00068971680.074
protein complex disassemblyGO:0043241400.060
protein localization to organelleGO:00333651850.057
regulation of synaptic growth at neuromuscular junctionGO:000858240.055
protein modification by small protein conjugationGO:00324461870.052
nucleoside phosphate metabolic processGO:00067533380.052
maintenance of locationGO:0051235890.051
nuclear transportGO:00511691390.049
macromolecular complex disassemblyGO:0032984430.049
ribose phosphate metabolic processGO:00196932910.048
nucleotide metabolic processGO:00091173320.048
membrane organizationGO:00610242450.048
intracellular protein transportGO:00068862040.047
positive regulation of protein modification processGO:00314012990.044
cation transportGO:00068123990.044
mrna metabolic processGO:0016071840.043
glycosyl compound metabolic processGO:19016572460.043
posttranscriptional regulation of gene expressionGO:00106081550.042
response to organonitrogen compoundGO:00102432460.042
cellular ketone metabolic processGO:0042180840.041
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.041
nucleoside triphosphate catabolic processGO:00091432050.041
cellular amine metabolic processGO:0044106440.040
oocyte axis specificationGO:000730920.039
regulation of cellular ketone metabolic processGO:0010565660.039
ras protein signal transductionGO:0007265770.039
purine containing compound metabolic processGO:00725213110.038
nucleocytoplasmic transportGO:00069131390.038
positive regulation of cellular amino acid metabolic processGO:004576430.038
germ cell developmentGO:00072811850.037
oxidation reduction processGO:00551143420.037
macromolecule catabolic processGO:00090572810.036
ribonucleotide metabolic processGO:00092592910.036
organonitrogen compound catabolic processGO:19015652640.036
organophosphate catabolic processGO:00464342320.036
regulation of neuron differentiationGO:00456642810.035
oocyte constructionGO:000730820.035
aromatic compound catabolic processGO:00194392860.035
regulation of protein localizationGO:00328802310.034
regulation of cellular amino acid metabolic processGO:000652150.034
regulation of transferase activityGO:00513382630.034
ribonucleotide catabolic processGO:00092612080.034
cellular protein complex disassemblyGO:0043624360.034
negative regulation of synapse assemblyGO:005196430.034
negative regulation of molecular functionGO:00440922580.033
pole plasm assemblyGO:000731520.033
endomembrane system organizationGO:00102561470.032
protein import into nucleusGO:0006606950.032
negative regulation of protein metabolic processGO:00512482820.032
positive regulation of cellular amine metabolic processGO:003324050.031
small gtpase mediated signal transductionGO:0007264970.031
nuclear importGO:0051170950.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.031
mrna processingGO:0006397630.030
cellular response to hormone stimulusGO:00328701500.030
cellular nitrogen compound catabolic processGO:00442702800.030
retrograde transport endosome to golgiGO:004214720.030
rna splicingGO:0008380540.029
axonogenesisGO:00074092740.029
amine metabolic processGO:0009308450.029
nucleoside metabolic processGO:00091162460.029
purine nucleoside metabolic processGO:00422782410.028
mrna splicing via spliceosomeGO:0000398430.028
carbohydrate metabolic processGO:00059752300.028
negative regulation of cellular component organizationGO:00511291940.028
developmental maturationGO:00217001930.028
ribonucleoside triphosphate catabolic processGO:00092031990.027
oocyte anterior posterior axis specificationGO:000731420.027
protein modification by small protein conjugation or removalGO:00706472070.027
protein localization to nucleusGO:00345041210.027
regulation of cellular component biogenesisGO:00440871810.027
purine ribonucleoside triphosphate metabolic processGO:00092052200.027
nucleotide catabolic processGO:00091662170.026
nucleoside phosphate catabolic processGO:19012922220.026
inclusion body assemblyGO:007084130.026
molting cycleGO:0042303900.026
synaptic transmissionGO:00072683290.026
ribonucleoside metabolic processGO:00091192450.026
regulation of organelle organizationGO:00330432890.026
covalent chromatin modificationGO:00165691630.026
purine containing compound catabolic processGO:00725232130.026
nucleoside catabolic processGO:00091642060.026
purine ribonucleotide catabolic processGO:00091542080.026
protein importGO:00170381010.025
regulation of proteolysisGO:00301621640.025
organic cyclic compound catabolic processGO:19013612950.025
lipid localizationGO:00108761260.025
purine ribonucleotide metabolic processGO:00091502900.025
purine ribonucleoside metabolic processGO:00461282410.025
negative regulation of cellular protein metabolic processGO:00322692470.025
chromatin modificationGO:00165681870.025
nucleoside triphosphate metabolic processGO:00091412300.025
cellular lipid metabolic processGO:00442553230.024
positive regulation of protein phosphorylationGO:00019342420.024
regulation of peptidase activityGO:0052547960.024
establishment of protein localization to organelleGO:00725941180.024
negative regulation of protein depolymerizationGO:1901880210.024
regulation of cell cycleGO:00517262810.024
skin developmentGO:00435882200.024
positive regulation of cell deathGO:00109422240.024
translationGO:0006412930.024
autophagyGO:0006914450.023
protein maturationGO:00516041760.023
regulation of hydrolase activityGO:00513362460.023
single organism nuclear importGO:1902593950.023
ribonucleoside triphosphate metabolic processGO:00091992200.023
protein ubiquitinationGO:00165671710.023
peptidyl amino acid modificationGO:00181933360.023
spermatogenesisGO:00072832840.023
heterocycle catabolic processGO:00467002800.023
protein catabolic processGO:00301632210.023
protein targetingGO:00066051430.023
cell type specific apoptotic processGO:00972852680.023
mitotic cell cycleGO:00002781950.023
regulation of kinase activityGO:00435492490.023
response to peptide hormoneGO:00434341270.023
organelle assemblyGO:00709251770.023
protein processingGO:00164851630.022
positive regulation of cell developmentGO:00107202370.022
regulation of protein kinase activityGO:00458592320.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
regulation of cellular amine metabolic processGO:0033238200.022
regulation of mapk cascadeGO:00434082480.022
microtubule cytoskeleton organizationGO:00002261570.022
circadian rhythmGO:00076231140.022
rna interferenceGO:001624620.022
development of primary sexual characteristicsGO:00451371430.022
cellular carbohydrate metabolic processGO:00442621190.022
epithelial tube morphogenesisGO:00605623030.022
response to extracellular stimulusGO:00099911270.022
regulation of vesicle mediated transportGO:00606271390.022
rhythmic processGO:00485111740.022
rna processingGO:00063961050.022
regulation of endocytosisGO:0030100690.021
synapse organizationGO:00508081250.021
response to acid chemicalGO:00011011110.021
carbohydrate biosynthetic processGO:0016051740.021
ribonucleoside catabolic processGO:00424542060.021
purine nucleotide metabolic processGO:00061633020.021
cellular homeostasisGO:00197252400.021
mapk cascadeGO:00001652810.021
regulation of intracellular transportGO:00323861590.021
male gamete generationGO:00482322850.021
purine nucleotide catabolic processGO:00061952110.021
cell growthGO:00160491300.021
negative regulation of cell sizeGO:004579230.021
microtubule based processGO:00070172360.020
response to peptideGO:19016521360.020
regulation of cell motilityGO:20001452360.020
purine ribonucleoside catabolic processGO:00461302050.020
protein localization to membraneGO:00726571080.020
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
nitrogen compound transportGO:00717052710.020
regulation of cell migrationGO:00303342190.020
regulation of anatomical structure sizeGO:00900661780.020
regulation of nucleotide metabolic processGO:00061401690.020
regulation of cell projection organizationGO:00313442060.020
cellular response to organonitrogen compoundGO:00714171450.020
positive regulation of organelle organizationGO:00106381280.020
regulation of cellular catabolic processGO:00313292420.019
ribonucleoprotein complex subunit organizationGO:0071826280.019
modification dependent protein catabolic processGO:00199411330.019
ameboidal type cell migrationGO:00016671280.019
purine nucleoside catabolic processGO:00061522050.019
rna splicing via transesterification reactionsGO:0000375430.019
receptor mediated endocytosisGO:0006898510.019
cellular protein catabolic processGO:00442571550.019
organelle fissionGO:00482851700.019
carbohydrate derivative catabolic processGO:19011362310.019
regulation of cell growthGO:0001558910.019
regulation of secretion by cellGO:19035302490.019
muscle cell differentiationGO:00426922610.019
positive regulation of protein serine threonine kinase activityGO:00719021060.019
glycosyl compound catabolic processGO:19016582060.019
positive regulation of hydrolase activityGO:00513451480.019
ion transmembrane transportGO:00342203610.019
positive regulation of nucleotide metabolic processGO:00459811140.019
apoptotic signaling pathwayGO:00971903060.019
regulation of clathrin mediated endocytosisGO:200036940.019
hexose metabolic processGO:0019318980.018
purine ribonucleoside triphosphate catabolic processGO:00092071990.018
cellular response to external stimulusGO:0071496880.018
regulation of translationGO:0006417710.018
fatty acid metabolic processGO:00066311210.018
response to insulinGO:00328681000.018
regulation of endopeptidase activityGO:0052548890.018
regulation of hormone levelsGO:00108172110.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
response to nutrient levelsGO:00316671090.018
establishment of protein localization to membraneGO:0090150540.018
locomotory behaviorGO:00076261950.018
negative regulation of nervous system developmentGO:00519611560.018
monocarboxylic acid metabolic processGO:00327871910.017
cellular protein complex assemblyGO:00436231160.017
regulation of cellular response to stressGO:00801351590.017
regulation of neuron projection developmentGO:00109751690.017
intracellular mrna localizationGO:000829840.017
positive regulation of kinase activityGO:00336741550.017
transmembrane transportGO:00550854120.017
regulation of cell activationGO:00508652890.017
response to light stimulusGO:00094161350.017
stem cell differentiationGO:00488632680.017
regulation of protein transportGO:00512231630.017
protein oligomerizationGO:0051259670.017
gland developmentGO:00487323300.017
response to radiationGO:00093141650.017
organelle localizationGO:00516401790.016
asymmetric neuroblast divisionGO:005505910.016
histone modificationGO:00165701590.016
rho protein signal transductionGO:0007266320.016
cellular response to lipidGO:00713961450.016
positive regulation of nervous system developmentGO:00519622210.016
gene silencing by rnaGO:0031047190.016
sensory perceptionGO:00076002450.016
respiratory system developmentGO:00605411900.016
lipid biosynthetic processGO:00086101790.016
cellular response to peptide hormone stimulusGO:0071375920.016
regulation of secretionGO:00510462740.016
regulation of establishment of protein localizationGO:00702011810.016
cellular chemical homeostasisGO:00550822150.016
positive regulation of programmed cell deathGO:00430682180.016
cellular response to peptideGO:1901653920.016
positive regulation of apoptotic processGO:00430652170.016
protein secretionGO:00093061110.016
negative regulation of intracellular signal transductionGO:19025321670.016
cell fate commitmentGO:00451652100.016
inflammatory responseGO:00069542440.016
chromatin organizationGO:00063252060.015
cognitionGO:00508901490.015
blastocyst developmentGO:0001824800.015
regulation of protein serine threonine kinase activityGO:00719001570.015
cation transmembrane transportGO:00986552660.015
meiotic nuclear divisionGO:00071261150.015
adult behaviorGO:00305341350.015
lipid transportGO:0006869980.015
striated muscle tissue developmentGO:00147062930.015
negative regulation of growthGO:0045926990.015
immune effector processGO:00022523210.014
epidermis developmentGO:00085441870.014
regulation of cytoskeleton organizationGO:00514931220.014
neuron migrationGO:00017641220.014
positive regulation of purine nucleotide catabolic processGO:0033123880.014
spermatid developmentGO:00072861080.014
lateral line system developmentGO:004892510.014
guanosine containing compound metabolic processGO:19010681440.014
wnt signaling pathwayGO:00160551880.014
regulation of purine nucleotide metabolic processGO:19005421690.014
sulfur compound metabolic processGO:00067901000.014
regulation of protein targetingGO:1903533610.014
dephosphorylationGO:00163111290.014
monosaccharide metabolic processGO:00059961060.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
regulation of ion transportGO:00432692150.014
negative regulation of organelle organizationGO:0010639900.014
g protein coupled receptor signaling pathwayGO:00071862430.014
chemotaxisGO:00069352470.014
lateral inhibitionGO:004633110.014
regulation of glucose metabolic processGO:0010906600.014
epithelial cell developmentGO:00020641590.014
protein depolymerizationGO:0051261340.014
glucose metabolic processGO:0006006920.014
positive regulation of cellular catabolic processGO:00313311480.013
response to inorganic substanceGO:0010035960.013
positive regulation of nucleotide catabolic processGO:0030813880.013
olfactory learningGO:000835520.013
cellular response to dna damage stimulusGO:00069742070.013
Human
cellular response to cytokine stimulusGO:00713451890.013
maternal determination of anterior posterior axis embryoGO:000835820.013
fat cell differentiationGO:00454441600.013
organic anion transportGO:00157111370.013
positive regulation of transferase activityGO:00513471670.013
adult locomotory behaviorGO:0008344910.013
cation homeostasisGO:00550802120.013
response to organic cyclic compoundGO:00140701980.013
regulation of cysteine type endopeptidase activityGO:2000116650.013
anion transportGO:00068201770.013
negative regulation of protein modification processGO:00314001630.013
regulation of mrna metabolic processGO:1903311430.013
calcium ion homeostasisGO:00550741270.013
reactive nitrogen species metabolic processGO:200105700.013
forebrain developmentGO:00309003020.013
regulation of purine nucleotide catabolic processGO:00331211220.013
dna metabolic processGO:00062593030.013
regulation of ras gtpase activityGO:0032318880.013
regulation of apoptotic signaling pathwayGO:20012331970.013
multicellular organismal homeostasisGO:00488711640.013
positive regulation of protein transportGO:0051222930.013
purine ribonucleoside monophosphate catabolic processGO:0009169570.012
neural tube developmentGO:00219151600.012
stem cell developmentGO:00488642190.012
cell maturationGO:00484691270.012
response to amino acidGO:0043200370.012
regulation of multi organism processGO:00439001110.012
regulation of wnt signaling pathwayGO:00301111230.012
organonitrogen compound biosynthetic processGO:19015661920.012
negative regulation of cell proliferationGO:00082852960.012
mitotic nuclear divisionGO:0007067480.012
neural tube formationGO:00018411080.012
regulation of lymphocyte activationGO:00512492400.012
positive regulation of protein kinase activityGO:00458601440.012
protein localization to plasma membraneGO:0072659570.012
plasma membrane organizationGO:0007009900.012
blood circulationGO:00080151950.012
regulation of microtubule polymerization or depolymerizationGO:0031110200.012
negative regulation of phosphorylationGO:00423261660.012
sequestering of calcium ionGO:0051208180.012
dendrite developmentGO:00163581150.012
cellular amide metabolic processGO:0043603580.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
cellular macromolecule catabolic processGO:00442652060.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.012
cellular response to growth factor stimulusGO:00713631970.012
transmission of nerve impulseGO:0019226760.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
regulation of protein maturationGO:1903317960.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
regulation of nucleoside metabolic processGO:00091181300.012
regulation of ion transmembrane transportGO:00347651190.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
metal ion homeostasisGO:00550651890.012
gonad developmentGO:00084061410.012
mitochondrion organizationGO:00070051340.011
female gamete generationGO:0007292740.011
telencephalon developmentGO:00215371860.011
response to growth factorGO:00708481980.011
multicellular organism growthGO:00352641610.011
compound eye developmentGO:004874910.011
mitotic cell cycle processGO:19030471590.011
response to oxygen levelsGO:0070482620.011
negative regulation of protein maturationGO:1903318790.011
small molecule catabolic processGO:0044282710.011
cell divisionGO:00513011200.011
potassium ion transportGO:0006813520.011
camera type eye developmentGO:00430102660.011
cell adhesionGO:00071553290.011
peptidyl tyrosine modificationGO:00182121450.011
defense response to other organismGO:00985421970.011
carbohydrate derivative biosynthetic processGO:19011371830.011
glucose homeostasisGO:00425931280.011
negative regulation of cell developmentGO:00107211690.011
spermatid differentiationGO:00485151150.011
positive regulation of necrotic cell deathGO:001094010.011
inorganic ion transmembrane transportGO:00986602340.011
nuclear exportGO:0051168340.011
asymmetric stem cell divisionGO:009872230.011
hatchingGO:003518840.011
skeletal muscle organ developmentGO:00605381630.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
extracellular matrix organizationGO:00301981470.011
regulation of intracellular protein transportGO:0033157820.011
positive regulation of gtpase activityGO:0043547850.011
regulation of cellular component sizeGO:00325351210.011
thermosensory behaviorGO:004004010.011
carbohydrate homeostasisGO:00335001280.011
innate immune responseGO:00450871570.011
nucleobase containing compound transportGO:0015931270.011
regulation of system processGO:00440572000.011
phagocytosisGO:0006909660.011
lymphocyte differentiationGO:00300982420.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
myosin filament assemblyGO:003103420.011
regulation of membrane potentialGO:00423911920.011
synapse assemblyGO:0007416560.010
regulation of map kinase activityGO:00434051200.010
regulation of cytoplasmic transportGO:19036491120.010
cellular response to extracellular stimulusGO:0031668810.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
nucleoside monophosphate metabolic processGO:0009123850.010
localization within membraneGO:005166840.010
cellular response to insulin stimulusGO:0032869780.010
nuclear divisionGO:00002801580.010
learning or memoryGO:00076111480.010
digestive system developmentGO:00551232000.010
reactive oxygen species biosynthetic processGO:190340980.010
regulation of carbohydrate metabolic processGO:0006109750.010
positive regulation of proteolysisGO:0045862850.010
response to temperature stimulusGO:0009266550.010
oogenesisGO:0048477560.010
regulation of ras protein signal transductionGO:00465781140.010
defense response to bacteriumGO:00427421190.010
organic acid catabolic processGO:0016054510.010
carbohydrate transportGO:0008643620.010
regulation of synaptic plasticityGO:0048167870.010
urogenital system developmentGO:00016552610.010
positive regulation of secretion by cellGO:19035321140.010
multicellular organismal signalingGO:0035637910.010

Uba1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.067
disease of anatomical entityDOID:700.067
eye and adnexa diseaseDOID:149200.027
sensory system diseaseDOID:005015500.027
neuropathyDOID:87000.025
central nervous system diseaseDOID:33100.022
neurodegenerative diseaseDOID:128900.018
retinal degenerationDOID:846600.016
retinal diseaseDOID:567900.016
eye diseaseDOID:561400.016
retinitis pigmentosaDOID:1058400.016
disease of metabolismDOID:001466700.015
neuromuscular diseaseDOID:44000.011
charcot marie tooth diseaseDOID:1059500.011
disease of cellular proliferationDOID:1456600.010