Mus musculus

42 known processes

Psme2

proteasome (prosome, macropain) 28 subunit, beta

(Aliases: AA589371,PA28b,AI788882)

Psme2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of proteolysisGO:0045862850.792
antigen processing and presentationGO:0019882470.727
positive regulation of peptidase activityGO:0010952490.705
antigen processing and presentation of exogenous antigenGO:0019884260.679
cellular macromolecule catabolic processGO:00442652060.510
positive regulation of endopeptidase activityGO:0010950430.508
regulation of peptidase activityGO:0052547960.475
positive regulation of hydrolase activityGO:00513451480.363
t cell proliferationGO:00420981200.348
cellular response to dna damage stimulusGO:00069742070.339
regulation of endopeptidase activityGO:0052548890.200
regulation of defense responseGO:00313472330.183
positive regulation of t cell mediated cytotoxicityGO:0001916150.173
modification dependent protein catabolic processGO:00199411330.164
regulation of t cell activationGO:00508631700.133
interspecies interaction between organismsGO:0044419830.132
lymphocyte proliferationGO:00466511640.126
ubiquitin dependent protein catabolic processGO:00065111290.117
regulation of intracellular transportGO:00323861590.117
fat cell differentiationGO:00454441600.111
regulation of lymphocyte activationGO:00512492400.110
symbiosis encompassing mutualism through parasitismGO:0044403830.105
innate immune responseGO:00450871570.103
protein catabolic processGO:00301632210.098
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988530.093
macromolecule catabolic processGO:00090572810.091
apoptotic signaling pathwayGO:00971903060.089
leukocyte differentiationGO:00025213420.071
positive regulation of cellular component biogenesisGO:0044089940.062
modification dependent macromolecule catabolic processGO:00436321330.061
oxidation reduction processGO:00551143420.060
cellular amino acid metabolic processGO:00065201030.059
proteolysis involved in cellular protein catabolic processGO:00516031470.053
regulation of t cell proliferationGO:0042129920.052
antigen processing and presentation of peptide antigen via mhc class iGO:000247490.050
response to lipopolysaccharideGO:00324961280.050
organic cyclic compound catabolic processGO:19013612950.048
muscle tissue developmentGO:00605373080.043
t cell activationGO:00421102890.042
arp2 3 complex mediated actin nucleationGO:003431430.042
negative regulation of protein modification processGO:00314001630.040
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.040
positive regulation of apoptotic signaling pathwayGO:2001235950.038
blood vessel morphogenesisGO:00485142850.038
cellular protein complex assemblyGO:00436231160.037
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.036
negative regulation of molecular functionGO:00440922580.035
nicotinamide nucleotide biosynthetic processGO:001935940.035
intracellular protein transportGO:00068862040.034
negative regulation of immune system processGO:00026832090.034
cellular amine metabolic processGO:0044106440.034
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.033
i kappab kinase nf kappab signalingGO:0007249850.033
metal ion homeostasisGO:00550651890.032
regulation of cellular ketone metabolic processGO:0010565660.032
nucleobase containing small molecule metabolic processGO:00550863520.031
response to organic cyclic compoundGO:00140701980.031
cellular ketone metabolic processGO:0042180840.030
cation transportGO:00068123990.030
inflammatory responseGO:00069542440.030
ras protein signal transductionGO:0007265770.030
cytoplasmic transportGO:00164822340.030
gland developmentGO:00487323300.030
epidermis developmentGO:00085441870.030
male gamete generationGO:00482322850.029
regulation of interleukin 1 alpha secretionGO:005070530.029
extrinsic apoptotic signaling pathwayGO:00971911260.028
type i interferon productionGO:0032606290.028
aromatic compound catabolic processGO:00194392860.028
protein polymerizationGO:0051258570.028
sequestering of metal ionGO:0051238190.027
regulation of cellular amino acid metabolic processGO:000652150.027
maintenance of locationGO:0051235890.027
superoxide metabolic processGO:0006801270.027
cellular protein catabolic processGO:00442571550.027
regulation of protein kinase activityGO:00458592320.027
negative regulation of natural killer cell mediated immunityGO:000271650.027
nucleoside phosphate metabolic processGO:00067533380.026
spermatogenesisGO:00072832840.026
cellular metal ion homeostasisGO:00068751510.025
regulation of protein targetingGO:1903533610.025
myeloid cell homeostasisGO:00022621140.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
carbohydrate derivative catabolic processGO:19011362310.023
glycosyl compound metabolic processGO:19016572460.023
purine containing compound catabolic processGO:00725232130.023
nuclear transportGO:00511691390.022
regulation of homeostatic processGO:00328441820.022
histone modificationGO:00165701590.022
homeostasis of number of cellsGO:00488722100.021
regulation of protein complex assemblyGO:0043254830.021
regulation of leukocyte proliferationGO:00706631210.021
positive regulation of lymphocyte activationGO:00512511400.021
multi multicellular organism processGO:00447061090.021
monocarboxylic acid metabolic processGO:00327871910.021
response to molecule of bacterial originGO:00022371430.020
proteasomal ubiquitin independent protein catabolic processGO:001049910.020
neuron deathGO:00709971540.020
regulation of cellular amine metabolic processGO:0033238200.020
lymphocyte mediated immunityGO:00024491390.020
reactive oxygen species metabolic processGO:0072593840.020
phagocytosisGO:0006909660.019
response to organonitrogen compoundGO:00102432460.019
leukocyte proliferationGO:00706611720.019
regulation of transferase activityGO:00513382630.019
regulation of protein localizationGO:00328802310.019
organophosphate biosynthetic processGO:00904071220.019
protein localization to organelleGO:00333651850.019
vesicle organizationGO:0016050600.019
ribose phosphate metabolic processGO:00196932910.019
cellular chemical homeostasisGO:00550822150.019
sensory perceptionGO:00076002450.018
positive regulation of cellular amine metabolic processGO:003324050.018
purine nucleoside metabolic processGO:00422782410.018
cellular ion homeostasisGO:00068731650.018
lymphocyte differentiationGO:00300982420.018
organic hydroxy compound metabolic processGO:19016152030.018
regulation of membrane potentialGO:00423911920.018
regulation of secretionGO:00510462740.018
protein maturationGO:00516041760.018
protein localization to nucleusGO:00345041210.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
nucleotide catabolic processGO:00091662170.018
regulation of hormone levelsGO:00108172110.018
mapk cascadeGO:00001652810.018
cellular modified amino acid metabolic processGO:0006575630.017
cellular homeostasisGO:00197252400.017
regulation of neuron deathGO:19012141340.017
mitochondrion organizationGO:00070051340.017
myosin filament organizationGO:003103330.017
zymogen activationGO:0031638410.017
nitrogen compound transportGO:00717052710.017
regulation of cytokine productionGO:00018172660.017
regulation of anatomical structure sizeGO:00900661780.017
progesterone metabolic processGO:004244840.017
regulation of cell activationGO:00508652890.017
negative regulation of cellular protein metabolic processGO:00322692470.017
regulation of body fluid levelsGO:00508781620.016
b cell activationGO:00421131610.016
cellular lipid metabolic processGO:00442553230.016
regulation of lymphocyte proliferationGO:00506701170.016
intrinsic apoptotic signaling pathwayGO:00971931320.016
ion transmembrane transportGO:00342203610.016
reactive nitrogen species metabolic processGO:200105700.016
negative regulation of phosphorylationGO:00423261660.016
regulation of interleukin 1 alpha productionGO:003265040.016
negative regulation of cell proliferationGO:00082852960.016
microtubule based processGO:00070172360.015
regulation of neuron apoptotic processGO:00435231220.015
positive regulation of leukocyte proliferationGO:0070665730.015
purine ribonucleotide catabolic processGO:00091542080.015
female sex differentiationGO:0046660840.015
pyridine nucleotide biosynthetic processGO:001936340.015
apoptotic mitochondrial changesGO:0008637480.015
regulation of mast cell differentiationGO:006037530.015
membrane organizationGO:00610242450.015
reactive oxygen species biosynthetic processGO:190340980.015
neuron apoptotic processGO:00514021420.015
positive regulation of lymphocyte proliferationGO:0050671700.015
positive regulation of tolerance induction dependent upon immune responseGO:000265410.014
regulation of reactive oxygen species biosynthetic processGO:190342620.014
synaptic transmissionGO:00072683290.014
cation homeostasisGO:00550802120.014
regulation of organelle organizationGO:00330432890.014
carbohydrate catabolic processGO:0016052320.014
cellular calcium ion homeostasisGO:00068741190.014
regulation of natural killer cell mediated cytotoxicityGO:0042269190.014
striated muscle tissue developmentGO:00147062930.014
negative regulation of phosphorus metabolic processGO:00105631840.014
cellular response to lipopolysaccharideGO:0071222770.014
dna repairGO:00062811070.014
rhythmic processGO:00485111740.014
rna interferenceGO:001624620.014
proteasomal protein catabolic processGO:0010498980.014
cellular response to hormone stimulusGO:00328701500.014
positive regulation of cell deathGO:00109422240.014
cellular response to oxidative stressGO:0034599760.014
organelle fissionGO:00482851700.013
positive regulation of organelle organizationGO:00106381280.013
neuromuscular processGO:0050905990.013
cellular response to lipidGO:00713961450.013
regulation of type i interferon mediated signaling pathwayGO:006033870.013
positive regulation of secretionGO:00510471300.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
nuclear importGO:0051170950.013
carbohydrate homeostasisGO:00335001280.013
leukocyte mediated cytotoxicityGO:0001909620.013
regulation of leukocyte differentiationGO:19021051590.013
positive regulation of programmed cell deathGO:00430682180.013
locomotory behaviorGO:00076261950.013
regulation of protein ubiquitinationGO:0031396520.013
positive regulation of growthGO:00459271040.013
protein importGO:00170381010.013
regulation of cell motilityGO:20001452360.013
regulation of mapk cascadeGO:00434082480.013
negative regulation of cell activationGO:00508661110.013
amine metabolic processGO:0009308450.013
regulation of epithelial cell proliferationGO:00506781410.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
purine ribonucleoside metabolic processGO:00461282410.012
positive regulation of protein modification processGO:00314012990.012
t cell differentiationGO:00302171740.012
regulation of metal ion transportGO:00109591060.012
regulation of vesicle mediated transportGO:00606271390.012
respiratory system developmentGO:00605411900.012
transmembrane transportGO:00550854120.012
lymphocyte homeostasisGO:0002260640.012
positive regulation of type i interferon productionGO:0032481140.012
negative regulation of lymphocyte proliferationGO:0050672450.012
negative regulation of protein metabolic processGO:00512482820.012
regulation of proteolysisGO:00301621640.012
negative regulation of cellular amine metabolic processGO:003323910.012
positive regulation of nervous system developmentGO:00519622210.012
negative regulation of intracellular signal transductionGO:19025321670.012
multicellular organismal homeostasisGO:00488711640.012
dna metabolic processGO:00062593030.012
negative regulation of cellular component organizationGO:00511291940.012
ribonucleoside metabolic processGO:00091192450.012
myeloid cell differentiationGO:00300992330.012
regulation of kinase activityGO:00435492490.012
dephosphorylationGO:00163111290.012
epithelial tube formationGO:00721751300.011
heterocycle catabolic processGO:00467002800.011
cytokine productionGO:00018163190.011
meiotic nuclear divisionGO:00071261150.011
regulation of hydrolase activityGO:00513362460.011
negative regulation of organelle organizationGO:0010639900.011
regulation of arp2 3 complex mediated actin nucleationGO:003431510.011
protein methylationGO:0006479810.011
regulation of purine nucleotide metabolic processGO:19005421690.011
positive regulation of apoptotic processGO:00430652170.011
positive regulation of mitotic cell cycleGO:0045931410.011
negative regulation of lymphocyte activationGO:0051250910.011
actin cytoskeleton organizationGO:00300362200.011
epithelial tube morphogenesisGO:00605623030.011
negative regulation of phosphate metabolic processGO:00459361840.011
positive regulation of cell cycleGO:0045787920.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
membrane depolarizationGO:0051899640.011
calcium ion homeostasisGO:00550741270.011
regulation of lipid metabolic processGO:00192161180.011
cell type specific apoptotic processGO:00972852680.011
positive regulation of cytosolic calcium ion concentrationGO:0007204650.011
regulation of establishment of protein localizationGO:00702011810.011
signal transduction in absence of ligandGO:0038034550.011
protein modification by small protein conjugationGO:00324461870.011
fertilizationGO:00095661270.011
purine deoxyribonucleoside triphosphate metabolic processGO:000921570.010
regulation of cellular component sizeGO:00325351210.010
purine nucleoside catabolic processGO:00061522050.010
cellular nitrogen compound catabolic processGO:00442702800.010
regulation of cell morphogenesis involved in differentiationGO:00107691510.010
nuclear divisionGO:00002801580.010
cell substrate adhesionGO:00315891300.010
protein processingGO:00164851630.010
regulation of antimicrobial peptide biosynthetic processGO:000280510.010
nucleoside phosphate biosynthetic processGO:1901293790.010
peptidyl amino acid modificationGO:00181933360.010
circulatory system processGO:00030131970.010

Psme2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.016
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014
cancerDOID:16200.013
organ system cancerDOID:005068600.013
gastrointestinal system cancerDOID:311900.013