Mus musculus

42 known processes

Psme1

proteasome (prosome, macropain) 28 subunit, alpha

(Aliases: PA28a,AW413925,MGC113815)

Psme1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antigen processing and presentation of exogenous antigenGO:0019884260.905
antigen processing and presentationGO:0019882470.822
positive regulation of peptidase activityGO:0010952490.747
regulation of peptidase activityGO:0052547960.540
t cell proliferationGO:00420981200.317
regulation of endopeptidase activityGO:0052548890.310
cellular response to dna damage stimulusGO:00069742070.287
interspecies interaction between organismsGO:0044419830.278
positive regulation of proteolysisGO:0045862850.234
positive regulation of endopeptidase activityGO:0010950430.202
positive regulation of t cell mediated cytotoxicityGO:0001916150.178
regulation of defense responseGO:00313472330.151
lymphocyte proliferationGO:00466511640.149
regulation of t cell activationGO:00508631700.145
innate immune responseGO:00450871570.141
positive regulation of hydrolase activityGO:00513451480.135
modification dependent protein catabolic processGO:00199411330.134
ubiquitin dependent protein catabolic processGO:00065111290.128
antigen processing and presentation of peptide antigen via mhc class iGO:000247490.117
regulation of lymphocyte activationGO:00512492400.117
protein catabolic processGO:00301632210.115
regulation of intracellular transportGO:00323861590.101
viral life cycleGO:0019058360.100
macromolecule catabolic processGO:00090572810.093
cellular amino acid metabolic processGO:00065201030.084
leukocyte proliferationGO:00706611720.084
proteolysis involved in cellular protein catabolic processGO:00516031470.081
modification dependent macromolecule catabolic processGO:00436321330.074
protein ubiquitinationGO:00165671710.073
cytoplasmic transportGO:00164822340.072
oxidation reduction processGO:00551143420.064
nucleobase containing small molecule metabolic processGO:00550863520.064
myosin filament organizationGO:003103330.061
negative regulation of natural killer cell mediated immunityGO:000271650.054
regulation of cytoplasmic transportGO:19036491120.054
regulation of cellular amine metabolic processGO:0033238200.052
regulation of cell activationGO:00508652890.050
cellular amine metabolic processGO:0044106440.050
intracellular protein transportGO:00068862040.049
maintenance of locationGO:0051235890.049
proteasomal protein catabolic processGO:0010498980.048
monocarboxylic acid metabolic processGO:00327871910.047
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.046
response to lipopolysaccharideGO:00324961280.045
cellular protein catabolic processGO:00442571550.044
muscle tissue developmentGO:00605373080.044
t cell activationGO:00421102890.043
regulation of cellular ketone metabolic processGO:0010565660.042
positive regulation of apoptotic signaling pathwayGO:2001235950.040
response to molecule of bacterial originGO:00022371430.039
cellular macromolecule catabolic processGO:00442652060.039
negative regulation of molecular functionGO:00440922580.039
establishment of protein localization to organelleGO:00725941180.038
protein polymerizationGO:0051258570.038
homeostasis of number of cellsGO:00488722100.037
cellular ketone metabolic processGO:0042180840.036
positive regulation of lymphocyte activationGO:00512511400.036
respiratory system developmentGO:00605411900.035
apoptotic signaling pathwayGO:00971903060.035
negative regulation of immune system processGO:00026832090.035
positive regulation of cellular amino acid metabolic processGO:004576430.034
regulation of cellular amino acid metabolic processGO:000652150.033
cell adhesionGO:00071553290.032
b cell activationGO:00421131610.032
striated muscle myosin thick filament assemblyGO:007168810.032
organic cyclic compound catabolic processGO:19013612950.031
actin cytoskeleton organizationGO:00300362200.030
epidermis developmentGO:00085441870.029
ras protein signal transductionGO:0007265770.029
protein modification by small protein conjugationGO:00324461870.029
cell type specific apoptotic processGO:00972852680.028
regulation of necroptotic processGO:0060544100.028
posttranscriptional regulation of gene expressionGO:00106081550.028
protein localization to organelleGO:00333651850.027
leukocyte differentiationGO:00025213420.027
female sex differentiationGO:0046660840.027
positive regulation of growthGO:00459271040.027
regulation of natural killer cell mediated cytotoxicityGO:0042269190.027
response to organonitrogen compoundGO:00102432460.026
positive regulation of cellular amine metabolic processGO:003324050.026
aromatic compound catabolic processGO:00194392860.026
negative regulation of protein phosphorylationGO:00019331260.026
anatomical structure homeostasisGO:00602491450.026
intrinsic apoptotic signaling pathwayGO:00971931320.025
lymphocyte mediated immunityGO:00024491390.025
purine ribonucleotide catabolic processGO:00091542080.025
nuclear transportGO:00511691390.025
reactive oxygen species metabolic processGO:0072593840.025
natural killer cell mediated immunityGO:0002228290.025
cation transportGO:00068123990.025
inflammatory responseGO:00069542440.024
regulation of cell motilityGO:20001452360.024
response to organic cyclic compoundGO:00140701980.024
regulation of t cell proliferationGO:0042129920.024
regulation of hormone levelsGO:00108172110.023
negative regulation of cell proliferationGO:00082852960.023
carbohydrate catabolic processGO:0016052320.023
regulation of homeostatic processGO:00328441820.023
locomotory behaviorGO:00076261950.022
metal ion homeostasisGO:00550651890.022
gland developmentGO:00487323300.022
positive regulation of cell activationGO:00508671580.021
response to radiationGO:00093141650.021
organelle assemblyGO:00709251770.021
regulation of vesicle mediated transportGO:00606271390.021
regulation of leukocyte differentiationGO:19021051590.021
regulation of arp2 3 complex mediated actin nucleationGO:003431510.021
negative regulation of protein modification processGO:00314001630.020
i kappab kinase nf kappab signalingGO:0007249850.020
cellular metal ion homeostasisGO:00068751510.020
chromatin modificationGO:00165681870.020
neuron deathGO:00709971540.020
negative regulation of protein metabolic processGO:00512482820.020
regulation of leukocyte mediated cytotoxicityGO:0001910380.020
regulation of cellular component sizeGO:00325351210.020
cellular lipid metabolic processGO:00442553230.019
carbohydrate derivative catabolic processGO:19011362310.019
extrinsic apoptotic signaling pathwayGO:00971911260.019
small molecule biosynthetic processGO:00442831320.019
regulation of apoptotic signaling pathwayGO:20012331970.019
protein modification by small protein conjugation or removalGO:00706472070.019
arp2 3 complex mediated actin nucleationGO:003431430.019
renal system developmentGO:00720012250.019
regulation of cytokine productionGO:00018172660.019
negative regulation of cellular protein metabolic processGO:00322692470.019
symbiosis encompassing mutualism through parasitismGO:0044403830.019
carbohydrate metabolic processGO:00059752300.019
male gamete generationGO:00482322850.019
cellular homeostasisGO:00197252400.019
protein localization to nucleusGO:00345041210.019
nucleoside phosphate metabolic processGO:00067533380.019
amine metabolic processGO:0009308450.019
regulation of organelle organizationGO:00330432890.018
reactive oxygen species biosynthetic processGO:190340980.018
spermatogenesisGO:00072832840.018
cellular modified amino acid metabolic processGO:0006575630.018
protein targetingGO:00066051430.018
peptide metabolic processGO:0006518460.018
epithelial tube morphogenesisGO:00605623030.018
vesicle organizationGO:0016050600.018
actomyosin structure organizationGO:0031032560.018
meiotic nuclear divisionGO:00071261150.018
regulation of protein localizationGO:00328802310.018
cellular response to cytokine stimulusGO:00713451890.018
regulation of cellular component biogenesisGO:00440871810.018
leukocyte mediated cytotoxicityGO:0001909620.018
sequestering of metal ionGO:0051238190.017
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.017
epinephrine secretionGO:004824210.017
negative regulation of cellular amine metabolic processGO:003323910.017
organonitrogen compound biosynthetic processGO:19015661920.017
rhythmic processGO:00485111740.017
myeloid cell homeostasisGO:00022621140.017
cellular ion homeostasisGO:00068731650.017
t cell homeostasisGO:0043029350.017
negative regulation of kinase activityGO:0033673810.017
chromatin organizationGO:00063252060.017
sulfur compound metabolic processGO:00067901000.017
intracellular transport of virusGO:007573310.017
nucleocytoplasmic transportGO:00069131390.017
protein importGO:00170381010.017
type i interferon productionGO:0032606290.016
protein import into nucleusGO:0006606950.016
lymphocyte activation involved in immune responseGO:0002285930.016
mitochondrion organizationGO:00070051340.016
regulation of leukocyte proliferationGO:00706631210.016
lipid localizationGO:00108761260.016
regulation of anatomical structure sizeGO:00900661780.016
cellular response to oxidative stressGO:0034599760.016
positive regulation of organelle organizationGO:00106381280.016
blood vessel morphogenesisGO:00485142850.016
morphogenesis of embryonic epitheliumGO:00163311590.016
rna interferenceGO:001624620.016
organophosphate biosynthetic processGO:00904071220.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
ribonucleotide metabolic processGO:00092592910.015
regulation of inflammatory responseGO:00507271470.015
epithelial cell migrationGO:0010631630.015
neuron apoptotic processGO:00514021420.015
purine containing compound catabolic processGO:00725232130.015
organic hydroxy compound metabolic processGO:19016152030.015
regulation of protein ubiquitinationGO:0031396520.015
urogenital system developmentGO:00016552610.015
positive regulation of leukocyte proliferationGO:0070665730.014
regulation of cellular response to stressGO:00801351590.014
histone modificationGO:00165701590.014
regulation of secretionGO:00510462740.014
nuclear importGO:0051170950.014
cellular protein complex assemblyGO:00436231160.014
membrane fusionGO:0061025380.014
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.014
positive regulation of apoptotic processGO:00430652170.014
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988530.014
multicellular organismal homeostasisGO:00488711640.014
regulation of lymphocyte proliferationGO:00506701170.014
dna metabolic processGO:00062593030.014
regulation of hydrolase activityGO:00513362460.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
cellular chemical homeostasisGO:00550822150.014
fat cell differentiationGO:00454441600.014
glycosyl compound metabolic processGO:19016572460.014
t cell differentiationGO:00302171740.014
response to light stimulusGO:00094161350.014
regulation of establishment of protein localizationGO:00702011810.014
positive regulation of t cell proliferationGO:0042102520.014
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.014
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.014
actin filament organizationGO:00070151130.014
peptidyl amino acid modificationGO:00181933360.014
neuromuscular processGO:0050905990.013
negative regulation of phosphorylationGO:00423261660.013
nucleotide metabolic processGO:00091173320.013
regulation of type i interferon mediated signaling pathwayGO:006033870.013
dna repairGO:00062811070.013
epithelial cell proliferationGO:00506731740.013
regulation of kinase activityGO:00435492490.013
regulation of neuron apoptotic processGO:00435231220.013
gonad developmentGO:00084061410.013
negative regulation of intracellular transportGO:0032387380.013
sequestering of calcium ionGO:0051208180.013
epithelial tube formationGO:00721751300.013
positive regulation of reactive oxygen species metabolic processGO:2000379110.013
calcium ion transportGO:00068161590.013
negative regulation of vesicle fusionGO:003133910.013
regulation of protein transportGO:00512231630.013
tube formationGO:00351481400.013
alpha amino acid metabolic processGO:1901605590.013
regulation of cell migrationGO:00303342190.013
response to growth factorGO:00708481980.013
regulation of transferase activityGO:00513382630.013
regulation of neuron deathGO:19012141340.013
carbohydrate homeostasisGO:00335001280.013
cytokine productionGO:00018163190.013
negative regulation of phosphate metabolic processGO:00459361840.013
negative regulation of intracellular signal transductionGO:19025321670.012
regulation of membrane potentialGO:00423911920.012
tissue migrationGO:0090130680.012
cellular response to lipopolysaccharideGO:0071222770.012
membrane organizationGO:00610242450.012
defense response to virusGO:0051607680.012
cellular response to hormone stimulusGO:00328701500.012
positive regulation of innate immune responseGO:0045089800.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
glycoprotein metabolic processGO:00091001160.012
negative regulation of neuron apoptotic processGO:0043524920.012
positive regulation of cell deathGO:00109422240.012
negative regulation of defense responseGO:0031348770.012
regulation of epithelial cell proliferationGO:00506781410.012
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.012
adaptive immune responseGO:00022501550.012
actin filament polymerizationGO:0030041440.012
immunoglobulin mediated immune responseGO:0016064690.012
cation homeostasisGO:00550802120.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
cell substrate adhesionGO:00315891300.012
muscle cell developmentGO:00550011330.012
regulation of ion transportGO:00432692150.012
membrane depolarizationGO:0051899640.012
lung developmentGO:00303241640.012
positive regulation of protein modification processGO:00314012990.012
positive regulation of leukocyte mediated immunityGO:0002705700.012
regulation of protein modification by small protein conjugation or removalGO:1903320570.011
positive regulation of lymphocyte proliferationGO:0050671700.011
regulation of interleukin 1 alpha productionGO:003265040.011
embryonic epithelial tube formationGO:00018381300.011
protein oligomerizationGO:0051259670.011
response to inorganic substanceGO:0010035960.011
negative regulation of organelle organizationGO:0010639900.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
compound eye developmentGO:004874910.011
generation of precursor metabolites and energyGO:00060911030.011
calcium ion homeostasisGO:00550741270.011
endomembrane system organizationGO:00102561470.011
actin polymerization or depolymerizationGO:0008154540.011
plasma membrane organizationGO:0007009900.011
regulation of response to woundingGO:19030341890.011
mapk cascadeGO:00001652810.011
zymogen activationGO:0031638410.011
striated muscle tissue developmentGO:00147062930.011
positive regulation of cellular component biogenesisGO:0044089940.011
regulation of body fluid levelsGO:00508781620.011
nitrogen compound transportGO:00717052710.011
cellular component assembly involved in morphogenesisGO:00109271390.011
negative regulation of cellular component organizationGO:00511291940.011
regulation of protein complex assemblyGO:0043254830.011
peptidyl lysine methylationGO:0018022290.011
regulation of purine nucleotide metabolic processGO:19005421690.011
microtubule based processGO:00070172360.011
proteasomal ubiquitin independent protein catabolic processGO:001049910.011
lipid biosynthetic processGO:00086101790.011
development of primary sexual characteristicsGO:00451371430.011
amide transportGO:00428861380.011
dephosphorylationGO:00163111290.011
protein maturationGO:00516041760.011
skeletal system developmentGO:00015013560.011
organelle fissionGO:00482851700.011
cellular response to lipidGO:00713961450.010
positive regulation of programmed cell deathGO:00430682180.010
regulation of proteolysisGO:00301621640.010
negative regulation of epithelial cell proliferationGO:0050680640.010
steroid metabolic processGO:00082021190.010
cellular calcium ion homeostasisGO:00068741190.010
multicellular organism growthGO:00352641610.010
regulation of protein kinase activityGO:00458592320.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010
regulation of plasminogen activationGO:001075540.010
regulation of metal ion transportGO:00109591060.010
nucleoside phosphate biosynthetic processGO:1901293790.010
covalent chromatin modificationGO:00165691630.010
lysosomal transportGO:0007041100.010
epinephrine transportGO:004824110.010
endocytosisGO:00068971680.010
neural tube developmentGO:00219151600.010
hormone metabolic processGO:0042445860.010

Psme1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.023
disease of anatomical entityDOID:700.023
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
organ system cancerDOID:005068600.022
gastrointestinal system cancerDOID:311900.022
nervous system diseaseDOID:86300.018
primary immunodeficiency diseaseDOID:61200.015
musculoskeletal system diseaseDOID:1700.012
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012