Mus musculus

241 known processes

Irak3

interleukin-1 receptor-associated kinase 3

(Aliases: AI563835,4833428C18Rik,IRAK-M)

Irak3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
activation of innate immune responseGO:0002218560.776
interleukin 1 mediated signaling pathwayGO:007049840.755
immune response regulating signaling pathwayGO:00027641250.660
positive regulation of innate immune responseGO:0045089800.526
regulation of defense responseGO:00313472330.489
activation of nf kappab inducing kinase activityGO:000725040.469
cytokine productionGO:00018163190.468
negative regulation of immune system processGO:00026832090.462
regulation of innate immune responseGO:0045088910.368
response to molecule of bacterial originGO:00022371430.332
cytokine mediated signaling pathwayGO:00192211150.319
regulation of interleukin 6 productionGO:0032675550.315
immune response activating signal transductionGO:00027571160.301
regulation of cell activationGO:00508652890.301
regulation of cytokine productionGO:00018172660.299
cellular response to biotic stimulusGO:0071216920.274
Mouse
activation of immune responseGO:00022531380.268
i kappab kinase nf kappab signalingGO:0007249850.253
pattern recognition receptor signaling pathwayGO:0002221470.240
immune effector processGO:00022523210.240
cellular response to lipopolysaccharideGO:0071222770.205
Mouse
stress activated protein kinase signaling cascadeGO:0031098810.200
Mouse
regulation of cellular response to stressGO:00801351590.191
Mouse
jnk cascadeGO:0007254720.181
Mouse
regulation of stress activated mapk cascadeGO:0032872690.177
Mouse
response to lipopolysaccharideGO:00324961280.174
innate immune response activating signal transductionGO:0002758500.172
regulation of sequence specific dna binding transcription factor activityGO:00510901060.171
immune response regulating cell surface receptor signaling pathwayGO:0002768800.162
mapk cascadeGO:00001652810.149
positive regulation of cytokine productionGO:00018191740.148
positive regulation of stress activated mapk cascadeGO:0032874480.146
Mouse
regulation of lymphocyte activationGO:00512492400.143
negative regulation of defense responseGO:0031348770.135
cytokine production involved in immune responseGO:0002367340.133
stress activated mapk cascadeGO:0051403800.131
Mouse
cellular amine metabolic processGO:0044106440.130
regulation of protein kinase activityGO:00458592320.128
negative regulation of protein phosphorylationGO:00019331260.127
regulation of leukocyte proliferationGO:00706631210.126
defense response to other organismGO:00985421970.126
toll like receptor signaling pathwayGO:0002224380.125
production of molecular mediator of immune responseGO:00024401030.118
response to organonitrogen compoundGO:00102432460.115
positive regulation of jun kinase activityGO:0043507300.112
Mouse
apoptotic signaling pathwayGO:00971903060.112
negative regulation of molecular functionGO:00440922580.107
cellular response to cytokine stimulusGO:00713451890.106
regulation of cellular amino acid metabolic processGO:000652150.104
immune response activating cell surface receptor signaling pathwayGO:0002429720.104
cellular response to molecule of bacterial originGO:0071219830.104
Mouse
lipopolysaccharide mediated signaling pathwayGO:0031663250.104
Mouse
positive regulation of jnk cascadeGO:0046330460.101
Mouse
regulation of cytokine production involved in immune responseGO:0002718260.100
positive regulation of protein modification processGO:00314012990.097
Mouse
regulation of protein serine threonine kinase activityGO:00719001570.096
negative regulation of phosphorus metabolic processGO:00105631840.095
positive regulation of defense responseGO:00313491240.094
lymphocyte proliferationGO:00466511640.094
lymphocyte mediated immunityGO:00024491390.092
homeostasis of number of cellsGO:00488722100.090
positive regulation of cellular amino acid metabolic processGO:004576430.090
regulation of mapk cascadeGO:00434082480.084
leukocyte proliferationGO:00706611720.082
positive regulation of nf kappab transcription factor activityGO:0051092300.082
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.081
regulation of response to woundingGO:19030341890.080
defense response to virusGO:0051607680.080
regulation of kinase activityGO:00435492490.080
negative regulation of cell proliferationGO:00082852960.079
protein ubiquitinationGO:00165671710.079
positive regulation of mapk cascadeGO:00434101700.077
Mouse
positive regulation of protein phosphorylationGO:00019342420.075
Mouse
cellular response to nitric oxideGO:007173240.075
negative regulation of cell activationGO:00508661110.075
regulation of cellular ketone metabolic processGO:0010565660.075
positive regulation of cytokine biosynthetic processGO:0042108400.074
response to peptidoglycanGO:003249490.074
positive regulation of cellular amine metabolic processGO:003324050.073
regulation of transferase activityGO:00513382630.073
response to nitric oxideGO:007173140.071
b cell activationGO:00421131610.071
cellular amino acid metabolic processGO:00065201030.071
response to dsrnaGO:0043331300.070
negative regulation of intracellular signal transductionGO:19025321670.069
t cell proliferationGO:00420981200.069
nik nf kappab signalingGO:0038061140.068
toll like receptor 4 signaling pathwayGO:003414290.067
Mouse
leukocyte differentiationGO:00025213420.067
negative regulation of cellular protein metabolic processGO:00322692470.066
negative regulation of toll like receptor signaling pathwayGO:0034122140.064
negative regulation of lymphocyte activationGO:0051250910.064
regulation of hydrolase activityGO:00513362460.063
regulation of interleukin 12 productionGO:0032655300.062
regulation of tumor necrosis factor productionGO:0032680490.062
regulation of nik nf kappab signalingGO:1901222100.060
regulation of t cell proliferationGO:0042129920.060
regulation of secretion by cellGO:19035302490.059
response to molecule of fungal originGO:000223840.059
antigen receptor mediated signaling pathwayGO:0050851640.058
t cell activationGO:00421102890.058
regulation of secretionGO:00510462740.058
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.057
Human Mouse
negative regulation of cytokine productionGO:0001818840.056
tumor necrosis factor superfamily cytokine productionGO:0071706510.056
response to oxidative stressGO:00069791230.056
regulation of cellular amine metabolic processGO:0033238200.056
protein polyubiquitinationGO:0000209330.053
cellular response to oxidative stressGO:0034599760.053
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.052
regulation of jnk cascadeGO:0046328620.052
Mouse
intrinsic apoptotic signaling pathwayGO:00971931320.051
cellular response to organonitrogen compoundGO:00714171450.051
regulation of leukocyte differentiationGO:19021051590.049
regulation of leukocyte mediated immunityGO:00027031040.049
adaptive immune responseGO:00022501550.049
t cell mediated immunityGO:0002456500.049
cytokine biosynthetic processGO:0042089680.048
cellular response to peptidoglycanGO:007122440.048
response to organic cyclic compoundGO:00140701980.048
protein complex disassemblyGO:0043241400.048
regulation of apoptotic signaling pathwayGO:20012331970.048
cellular ketone metabolic processGO:0042180840.047
regulation of b cell proliferationGO:0030888390.047
tube formationGO:00351481400.047
positive regulation of protein kinase activityGO:00458601440.046
Mouse
regulation of map kinase activityGO:00434051200.046
regulation of establishment of protein localizationGO:00702011810.046
regulation of production of molecular mediator of immune responseGO:0002700650.046
negative regulation of t cell activationGO:0050868650.046
heterocycle catabolic processGO:00467002800.045
positive regulation of cell activationGO:00508671580.045
macromolecule catabolic processGO:00090572810.044
multicellular organismal homeostasisGO:00488711640.044
regulation of membrane potentialGO:00423911920.044
negative regulation of protein metabolic processGO:00512482820.044
negative regulation of nf kappab transcription factor activityGO:0032088150.043
Human
regulation of toll like receptor signaling pathwayGO:0034121200.043
amine metabolic processGO:0009308450.043
positive regulation of programmed cell deathGO:00430682180.043
regulation of cytokine biosynthetic processGO:0042035590.042
inflammatory responseGO:00069542440.041
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.041
organic cyclic compound catabolic processGO:19013612950.041
cell activation involved in immune responseGO:00022631260.041
regulation of cellular catabolic processGO:00313292420.041
cytokine metabolic processGO:0042107710.040
positive regulation of immune effector processGO:00026991070.040
nitrogen compound transportGO:00717052710.040
aromatic compound catabolic processGO:00194392860.040
spermatogenesisGO:00072832840.040
interferon beta productionGO:0032608160.040
cellular nitrogen compound catabolic processGO:00442702800.040
purine ribonucleoside triphosphate metabolic processGO:00092052200.039
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.039
leukocyte apoptotic processGO:0071887710.039
extrinsic apoptotic signaling pathwayGO:00971911260.039
skin developmentGO:00435882200.039
regulation of lymphocyte mediated immunityGO:0002706840.038
positive regulation of transferase activityGO:00513471670.038
Mouse
ras protein signal transductionGO:0007265770.038
peptidyl amino acid modificationGO:00181933360.038
protein catabolic processGO:00301632210.038
tissue homeostasisGO:00018941150.038
purine containing compound catabolic processGO:00725232130.038
innate immune responseGO:00450871570.038
positive regulation of protein serine threonine kinase activityGO:00719021060.038
Mouse
anion transportGO:00068201770.038
positive regulation of apoptotic processGO:00430652170.037
regulation of protein transportGO:00512231630.037
morphogenesis of embryonic epitheliumGO:00163311590.037
antimicrobial peptide productionGO:000277520.037
positive regulation of kinase activityGO:00336741550.036
Mouse
male gamete generationGO:00482322850.036
purine ribonucleoside metabolic processGO:00461282410.036
negative regulation of immune effector processGO:0002698550.036
cell adhesionGO:00071553290.036
regulation of reactive oxygen species metabolic processGO:2000377400.036
reactive nitrogen species metabolic processGO:200105700.035
positive regulation of interleukin 6 productionGO:0032755370.035
regulation of protein catabolic processGO:00421761080.035
rho protein signal transductionGO:0007266320.035
ossificationGO:00015032160.035
interleukin 6 productionGO:0032635580.035
glycosyl compound metabolic processGO:19016572460.034
positive regulation of cell deathGO:00109422240.034
action potentialGO:0001508780.034
negative regulation of phosphate metabolic processGO:00459361840.034
positive regulation of interferon alpha productionGO:003272740.034
negative regulation of cellular amine metabolic processGO:003323910.033
negative regulation of tumor necrosis factor productionGO:0032720170.033
organic hydroxy compound transportGO:0015850930.033
Mouse
transmembrane transportGO:00550854120.033
negative regulation of map kinase activityGO:0043407340.033
protein modification by small protein conjugationGO:00324461870.033
leukocyte mediated immunityGO:00024431740.033
response to interleukin 1GO:0070555110.033
regulation of bindingGO:00510981110.033
negative regulation of transferase activityGO:0051348850.032
membrane organizationGO:00610242450.032
reactive oxygen species metabolic processGO:0072593840.032
cellular response to lipidGO:00713961450.032
Mouse
interleukin 12 productionGO:0032615320.032
interleukin 2 productionGO:0032623330.032
myeloid leukocyte activationGO:0002274830.031
negative regulation of interleukin 6 productionGO:0032715170.031
regulation of multi organism processGO:00439001110.031
ribonucleoside metabolic processGO:00091192450.031
b cell proliferationGO:0042100530.031
negative regulation of cholesterol transportGO:003237540.031
Mouse
leukocyte migrationGO:00509001240.031
regulation of organ morphogenesisGO:20000271440.030
regulation of alpha beta t cell activationGO:0046634530.030
nucleotide metabolic processGO:00091173320.030
positive regulation of leukocyte proliferationGO:0070665730.030
b cell apoptotic processGO:0001783190.030
digestive system developmentGO:00551232000.030
lymphocyte apoptotic processGO:0070227540.030
fat cell differentiationGO:00454441600.030
lymphocyte differentiationGO:00300982420.030
positive regulation of secretionGO:00510471300.030
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
nucleoside phosphate catabolic processGO:19012922220.029
regulation of protein localizationGO:00328802310.029
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.029
peptidyl tyrosine phosphorylationGO:00181081430.029
type i interferon productionGO:0032606290.029
positive regulation of macroautophagyGO:001623930.029
lipid biosynthetic processGO:00086101790.029
regulation of response to biotic stimulusGO:0002831380.029
positive regulation of lymphocyte activationGO:00512511400.028
humoral immune responseGO:0006959570.028
regulation of t cell activationGO:00508631700.028
negative regulation of lymphocyte proliferationGO:0050672450.028
carbohydrate derivative catabolic processGO:19011362310.028
negative regulation of protein serine threonine kinase activityGO:0071901490.028
positive regulation of antimicrobial humoral responseGO:000276020.028
protein localization to organelleGO:00333651850.028
ripoptosome assembly involved in necroptotic processGO:190102660.028
nucleoside phosphate metabolic processGO:00067533380.027
nucleoside metabolic processGO:00091162460.027
anatomical structure homeostasisGO:00602491450.027
organophosphate catabolic processGO:00464342320.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.027
positive regulation of cytokine production involved in immune responseGO:0002720190.027
epidermis developmentGO:00085441870.027
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.027
positive regulation of antimicrobial peptide productionGO:000222510.027
protein modification by small protein conjugation or removalGO:00706472070.026
purine nucleotide catabolic processGO:00061952110.026
organonitrogen compound catabolic processGO:19015652640.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
neural tube formationGO:00018411080.026
nucleoside triphosphate metabolic processGO:00091412300.025
negative regulation of cellular amino acid metabolic processGO:004576300.025
response to inorganic substanceGO:0010035960.025
regulation of proteolysisGO:00301621640.025
transmission of nerve impulseGO:0019226760.025
negative regulation of apoptotic signaling pathwayGO:20012341040.025
regulation of chemokine productionGO:0032642300.025
embryonic epithelial tube formationGO:00018381300.025
modification dependent macromolecule catabolic processGO:00436321330.025
positive regulation of cellular catabolic processGO:00313311480.025
dna metabolic processGO:00062593030.025
toll like receptor 2 signaling pathwayGO:003413460.025
Mouse
purine nucleotide metabolic processGO:00061633020.024
macrophage cytokine productionGO:001093490.024
regionalizationGO:00030023370.024
cytokine secretionGO:0050663720.024
regulation of cell motilityGO:20001452360.024
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.024
negative regulation of t cell proliferationGO:0042130380.024
lymphocyte activation involved in immune responseGO:0002285930.024
digestive tract developmentGO:00485651900.024
myeloid leukocyte cytokine productionGO:0061082120.024
regulation of cell adhesionGO:00301551540.024
neuronal action potentialGO:0019228540.024
respiratory tube developmentGO:00303231670.024
sterol transportGO:0015918380.024
Mouse
peptidyl serine modificationGO:0018209830.024
nucleobase containing small molecule metabolic processGO:00550863520.024
regulation of homeostatic processGO:00328441820.024
posttranscriptional regulation of gene expressionGO:00106081550.023
mitochondrion organizationGO:00070051340.023
small molecule biosynthetic processGO:00442831320.023
organic anion transportGO:00157111370.023
cellular response to growth factor stimulusGO:00713631970.023
organic hydroxy compound metabolic processGO:19016152030.023
regulation of adaptive immune responseGO:0002819900.023
cytoplasmic transportGO:00164822340.023
positive regulation of production of molecular mediator of immune responseGO:0002702450.023
regulation of organelle organizationGO:00330432890.023
negative regulation of b cell activationGO:0050869270.023
regulation of cell cycleGO:00517262810.023
positive regulation of interleukin 8 productionGO:003275720.023
protein autophosphorylationGO:0046777610.023
regulation of leukocyte apoptotic processGO:2000106560.023
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.022
interleukin 6 biosynthetic processGO:0042226120.022
negative regulation of protein modification processGO:00314001630.022
nucleoside catabolic processGO:00091642060.022
b cell homeostasisGO:0001782340.022
nucleotide catabolic processGO:00091662170.022
cation transportGO:00068123990.022
response to extracellular stimulusGO:00099911270.022
ribonucleoside triphosphate catabolic processGO:00092031990.022
regulation of t cell mediated immunityGO:0002709340.022
cation transmembrane transportGO:00986552660.021
nucleic acid phosphodiester bond hydrolysisGO:0090305490.021
defense response to bacteriumGO:00427421190.021
purine nucleoside metabolic processGO:00422782410.021
keratinocyte differentiationGO:0030216480.021
epithelial tube formationGO:00721751300.021
nucleoside triphosphate catabolic processGO:00091432050.021
intracellular receptor signaling pathwayGO:0030522740.021
alpha beta t cell proliferationGO:0046633210.021
regulation of lymphocyte proliferationGO:00506701170.021
detection of molecule of bacterial originGO:003249020.021
cellular response to external stimulusGO:0071496880.021
positive regulation of lymphocyte mediated immunityGO:0002708620.021
organonitrogen compound biosynthetic processGO:19015661920.020
myeloid cell differentiationGO:00300992330.020
positive regulation of leukocyte differentiationGO:1902107860.020
chromatin organizationGO:00063252060.020
cell type specific apoptotic processGO:00972852680.020
blood vessel morphogenesisGO:00485142850.020
extracellular matrix organizationGO:00301981470.020
regulation of protein processingGO:0070613960.020
regulation of tolerance inductionGO:0002643100.020
ribose phosphate metabolic processGO:00196932910.020
hormone secretionGO:00468791280.020
lipid localizationGO:00108761260.020
Mouse
organophosphate biosynthetic processGO:00904071220.020
b cell differentiationGO:0030183780.020
leukocyte activation involved in immune responseGO:00023661260.020
epithelial cell proliferationGO:00506731740.020
negative regulation of multi organism processGO:0043901680.020
ribonucleoside catabolic processGO:00424542060.020
carbohydrate derivative biosynthetic processGO:19011371830.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
inorganic cation transmembrane transportGO:00986622070.020
purine nucleoside triphosphate metabolic processGO:00091442260.019
skeletal system developmentGO:00015013560.019
negative regulation of phosphorylationGO:00423261660.019
negative regulation of mapk cascadeGO:0043409650.019
tube closureGO:0060606910.019
sensory perceptionGO:00076002450.019
ribonucleotide catabolic processGO:00092612080.019
regulation of interleukin 6 biosynthetic processGO:0045408110.019
purine ribonucleoside catabolic processGO:00461302050.019
regulation of purine nucleotide metabolic processGO:19005421690.019
positive regulation of leukocyte mediated immunityGO:0002705700.019
regulation of neuron differentiationGO:00456642810.019
organic hydroxy compound biosynthetic processGO:1901617770.019
regulation of antimicrobial peptide productionGO:000278410.019
glycosyl compound catabolic processGO:19016582060.019
compound eye developmentGO:004874910.019
response to starvationGO:0042594650.019
regulation of endopeptidase activityGO:0052548890.018
positive regulation of b cell activationGO:0050871490.018
sensory organ morphogenesisGO:00905962420.018
wnt signaling pathwayGO:00160551880.018
cellular lipid metabolic processGO:00442553230.018
reactive oxygen species biosynthetic processGO:190340980.018
negative regulation of leukocyte proliferationGO:0070664460.018
protein processingGO:00164851630.018
regulation of lipid transportGO:0032368360.018
Mouse
negative regulation of cell cycleGO:00457861230.018
antibacterial peptide productionGO:000277820.018
organic acid biosynthetic processGO:0016053860.018
interleukin 5 secretionGO:007260320.018
regulation of reactive oxygen species biosynthetic processGO:190342620.018
positive regulation of lymphocyte proliferationGO:0050671700.018
stem cell developmentGO:00488642190.018
regulation of lymphocyte differentiationGO:00456191070.018
regulation of b cell activationGO:0050864810.018
cellular protein catabolic processGO:00442571550.018
regulation of protein complex disassemblyGO:0043244280.018
regulation of cytoplasmic transportGO:19036491120.018
odontogenesis of dentin containing toothGO:0042475660.017
synaptic transmissionGO:00072683290.017
oxidation reduction processGO:00551143420.017
regulation of cellular response to growth factor stimulusGO:0090287820.017
lipid transportGO:0006869980.017
Mouse
angiogenesisGO:00015252010.017
myeloid leukocyte differentiationGO:00025731190.017
regulation of protein complex assemblyGO:0043254830.017
positive regulation of protein transportGO:0051222930.017
neural tube closureGO:0001843900.017
neuron deathGO:00709971540.017
positive regulation of hydrolase activityGO:00513451480.017
regulation of type i interferon productionGO:0032479220.017
regulation of interferon beta productionGO:0032648130.017
positive regulation of interleukin 6 biosynthetic processGO:004541060.017
regulation of dna bindingGO:0051101390.017
ubiquitin dependent protein catabolic processGO:00065111290.017
epithelial tube morphogenesisGO:00605623030.017
urogenital system developmentGO:00016552610.017
cellular response to extracellular stimulusGO:0031668810.017
purine containing compound metabolic processGO:00725213110.017
protein k63 linked ubiquitinationGO:007053460.017
regulation of hormone levelsGO:00108172110.017
leukocyte homeostasisGO:0001776790.017
positive regulation of chemokine productionGO:0032722220.017
neural tube developmentGO:00219151600.016
lymphocyte homeostasisGO:0002260640.016
tumor necrosis factor productionGO:0032640500.016
b cell mediated immunityGO:0019724710.016
monocarboxylic acid biosynthetic processGO:0072330610.016
muscle cell differentiationGO:00426922610.016
response to growth factorGO:00708481980.016
regulation of nucleotide catabolic processGO:00308111220.016
regulation of antimicrobial peptide biosynthetic processGO:000280510.016
fertilizationGO:00095661270.016
gland developmentGO:00487323300.016
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.016
digestive tract morphogenesisGO:00485461470.016
inorganic ion transmembrane transportGO:00986602340.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.016
wound healingGO:00420601570.016
regulation of ion transportGO:00432692150.016
protein kinase b signalingGO:0043491740.016
regulation of antimicrobial humoral responseGO:000275930.016
autophagyGO:0006914450.016
epithelial cell developmentGO:00020641590.016
regulation of protein secretionGO:0050708820.016
regulation of cytokine secretion involved in immune responseGO:000273940.016
g protein coupled receptor signaling pathwayGO:00071862430.016
necroptotic processGO:0070266210.016
tissue remodelingGO:00487711020.016
negative regulation of secretion by cellGO:1903531540.016
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.015
ion transmembrane transportGO:00342203610.015
camera type eye developmentGO:00430102660.015
negative regulation of cellular component organizationGO:00511291940.015
Human
positive regulation of cell adhesionGO:0045785800.015
carbohydrate homeostasisGO:00335001280.015
small gtpase mediated signal transductionGO:0007264970.015
purine ribonucleotide metabolic processGO:00091502900.015
positive regulation of t cell cytokine productionGO:000272650.015
positive regulation of map kinase activityGO:0043406840.015
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
response to exogenous dsrnaGO:0043330220.015
regulation of cytoskeleton organizationGO:00514931220.015
primary neural tube formationGO:0014020950.015
organic acid transportGO:00158491010.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.015
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.015
regulation of response to cytokine stimulusGO:0060759230.015
cell substrate adhesionGO:00315891300.015
spermatid differentiationGO:00485151150.015
cellular chemical homeostasisGO:00550822150.015
cellular homeostasisGO:00197252400.015
cellular response to interleukin 1GO:007134780.015
negative regulation of protein catabolic processGO:0042177360.015
response to nutrient levelsGO:00316671090.015
positive regulation of reactive oxygen species metabolic processGO:2000379110.015
t cell receptor signaling pathwayGO:0050852460.015
regulation of sterol transportGO:0032371170.015
Mouse
organelle localizationGO:00516401790.015
negative regulation of endopeptidase activityGO:0010951440.015
regulation of jun kinase activityGO:0043506400.015
Mouse
histone modificationGO:00165701590.015
protein maturationGO:00516041760.015
negative regulation of growthGO:0045926990.015
nucleocytoplasmic transportGO:00069131390.015
alcohol metabolic processGO:00060661160.015
positive regulation of secretion by cellGO:19035321140.015
macromolecular complex disassemblyGO:0032984430.014
positive regulation of myeloid cell differentiationGO:0045639430.014
regulation of interferon beta biosynthetic processGO:004535740.014
gtp catabolic processGO:00061841430.014
signal transduction in absence of ligandGO:0038034550.014
carbohydrate metabolic processGO:00059752300.014
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.014
p38mapk cascadeGO:003806640.014
interleukin 10 secretionGO:007260840.014
positive regulation of bindingGO:0051099490.014
cellular response to abiotic stimulusGO:0071214560.014
amide transportGO:00428861380.014
antibacterial peptide biosynthetic processGO:000278020.014
embryonic organ morphogenesisGO:00485622760.014
regulation of osteoblast differentiationGO:0045667670.014
regulation of nucleotide metabolic processGO:00061401690.014
lung developmentGO:00303241640.014

Irak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.045
organ system cancerDOID:005068600.045
disease of cellular proliferationDOID:1456600.045
disease of anatomical entityDOID:700.025
musculoskeletal system diseaseDOID:1700.025
hematologic cancerDOID:253100.022
immune system cancerDOID:006008300.022
connective tissue diseaseDOID:6500.020
disease of metabolismDOID:001466700.018
nervous system diseaseDOID:86300.016