Mus musculus

65 known processes

Aco1

aconitase 1

(Aliases: Irp1,Aco-1,AI256519,Irebp)

Aco1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sterol metabolic processGO:0016125580.333
acylglycerol metabolic processGO:0006639550.325
oxidation reduction processGO:00551143420.324
glycerolipid metabolic processGO:00464861220.318
cellular lipid metabolic processGO:00442553230.268
organic hydroxy compound metabolic processGO:19016152030.231
sulfur compound metabolic processGO:00067901000.216
triglyceride metabolic processGO:0006641510.205
cholesterol metabolic processGO:0008203560.176
cofactor metabolic processGO:0051186800.160
Mouse
fatty acid metabolic processGO:00066311210.147
alcohol metabolic processGO:00060661160.126
neutral lipid metabolic processGO:0006638570.126
steroid metabolic processGO:00082021190.113
glutamine family amino acid biosynthetic processGO:000908420.103
lipid biosynthetic processGO:00086101790.094
carboxylic acid catabolic processGO:0046395510.082
generation of precursor metabolites and energyGO:00060911030.078
cellular ketone metabolic processGO:0042180840.075
transmembrane transportGO:00550854120.074
positive regulation of mitochondrial calcium ion concentrationGO:005156130.069
cellular amino acid metabolic processGO:00065201030.066
peroxisome organizationGO:000703170.065
carboxylic acid biosynthetic processGO:0046394860.061
positive regulation of interleukin 8 productionGO:003275720.058
small molecule catabolic processGO:0044282710.056
glutamate biosynthetic processGO:000653720.056
regulation of cellular ketone metabolic processGO:0010565660.056
response to organic cyclic compoundGO:00140701980.055
cellular amino acid biosynthetic processGO:0008652220.052
alpha amino acid biosynthetic processGO:1901607150.052
response to oxidative stressGO:00069791230.052
organophosphate biosynthetic processGO:00904071220.051
small molecule biosynthetic processGO:00442831320.051
amine metabolic processGO:0009308450.051
defense response to other organismGO:00985421970.050
nucleoside bisphosphate biosynthetic processGO:003386660.049
cofactor transportGO:005118140.047
cellular response to oxidative stressGO:0034599760.045
coenzyme metabolic processGO:0006732520.043
regulation of interleukin 8 productionGO:003267730.042
organic acid catabolic processGO:0016054510.041
apoptotic signaling pathwayGO:00971903060.041
carbohydrate derivative biosynthetic processGO:19011371830.041
anion transportGO:00068201770.040
organic anion transportGO:00157111370.038
regulation of cytokine productionGO:00018172660.036
regulation of intracellular transportGO:00323861590.036
energy derivation by oxidation of organic compoundsGO:0015980770.036
intracellular protein transportGO:00068862040.035
cytokine productionGO:00018163190.035
regulation of ion transportGO:00432692150.035
positive regulation of protein modification processGO:00314012990.035
carbohydrate metabolic processGO:00059752300.035
regulation of cellular amino acid metabolic processGO:000652150.035
ion transmembrane transportGO:00342203610.035
nuclear transportGO:00511691390.034
cation transportGO:00068123990.034
organonitrogen compound biosynthetic processGO:19015661920.034
Mouse
interleukin 8 productionGO:003263740.034
lipid localizationGO:00108761260.033
response to reactive oxygen speciesGO:0000302560.033
nucleocytoplasmic transportGO:00069131390.033
cellular amine metabolic processGO:0044106440.032
nitrogen compound transportGO:00717052710.032
membrane organizationGO:00610242450.032
nucleobase containing small molecule metabolic processGO:00550863520.032
peptidyl amino acid modificationGO:00181933360.032
regulation of protein localizationGO:00328802310.032
monocarboxylic acid metabolic processGO:00327871910.032
cation homeostasisGO:00550802120.031
chemotaxisGO:00069352470.031
ossificationGO:00015032160.031
cellular response to lipidGO:00713961450.031
positive regulation of interferon alpha productionGO:003272740.031
lipid catabolic processGO:0016042690.031
glycerolipid biosynthetic processGO:0045017500.031
regulation of establishment of protein localizationGO:00702011810.030
coenzyme biosynthetic processGO:0009108230.030
ribonucleoside bisphosphate metabolic processGO:003387590.030
organic cyclic compound catabolic processGO:19013612950.030
acyl coa metabolic processGO:0006637190.030
intrinsic apoptotic signaling pathwayGO:00971931320.029
cellular respirationGO:0045333380.029
nucleotide metabolic processGO:00091173320.028
reactive oxygen species metabolic processGO:0072593840.028
purine containing compound biosynthetic processGO:0072522700.028
response to inorganic substanceGO:0010035960.028
Human
myeloid cell differentiationGO:00300992330.028
Mouse
regulation of organelle organizationGO:00330432890.027
regulation of cellular amine metabolic processGO:0033238200.027
purine nucleotide metabolic processGO:00061633020.027
lipid oxidationGO:0034440290.027
cellular response to cytokine stimulusGO:00713451890.027
regulation of defense responseGO:00313472330.027
multicellular organismal agingGO:0010259240.027
sensory perceptionGO:00076002450.026
membrane lipid biosynthetic processGO:0046467320.026
cellular homeostasisGO:00197252400.026
cytoplasmic transportGO:00164822340.026
protein modification by small protein conjugation or removalGO:00706472070.026
cellular chemical homeostasisGO:00550822150.026
protein targetingGO:00066051430.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
response to radiationGO:00093141650.026
mitochondrial calcium ion homeostasisGO:005156070.025
fatty acid catabolic processGO:0009062250.025
protein tetramerizationGO:0051262230.025
maintenance of locationGO:0051235890.025
t cell activationGO:00421102890.025
positive regulation of cellular amine metabolic processGO:003324050.025
negative regulation of molecular functionGO:00440922580.024
inorganic cation transmembrane transportGO:00986622070.024
regulation of apoptotic signaling pathwayGO:20012331970.024
organonitrogen compound catabolic processGO:19015652640.024
regulation of cellular catabolic processGO:00313292420.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.024
positive regulation of cell deathGO:00109422240.024
very long chain fatty acid metabolic processGO:000003880.023
protein homooligomerizationGO:0051260430.023
leukocyte differentiationGO:00025213420.023
Mouse
heterocycle catabolic processGO:00467002800.023
purine nucleotide biosynthetic processGO:0006164650.023
ribose phosphate metabolic processGO:00196932910.023
ribose phosphate biosynthetic processGO:0046390590.023
purine ribonucleotide metabolic processGO:00091502900.023
regulation of system processGO:00440572000.022
fatty acid oxidationGO:0019395280.022
cellular lipid catabolic processGO:0044242520.022
response to oxygen radicalGO:0000305160.022
spermatogenesisGO:00072832840.022
cellular metal ion homeostasisGO:00068751510.022
cellular carbohydrate metabolic processGO:00442621190.021
regulation of ion transmembrane transportGO:00347651190.021
histone modificationGO:00165701590.021
response to light stimulusGO:00094161350.021
regulation of hormone levelsGO:00108172110.021
cellular response to organic cyclic compoundGO:0071407870.021
innate immune responseGO:00450871570.021
protein localization to organelleGO:00333651850.021
regulation of protein transportGO:00512231630.021
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.020
cellular modified amino acid metabolic processGO:0006575630.020
cellular ion homeostasisGO:00068731650.020
inorganic ion transmembrane transportGO:00986602340.020
purine nucleoside metabolic processGO:00422782410.020
lipid homeostasisGO:0055088630.020
cellular alcohol biosynthetic processGO:004410830.020
gland developmentGO:00487323300.020
thioester metabolic processGO:0035383190.020
organic acid biosynthetic processGO:0016053860.020
chromatin organizationGO:00063252060.020
cholesterol homeostasisGO:0042632440.020
gonad developmentGO:00084061410.020
phospholipid metabolic processGO:0006644870.019
organic acid transportGO:00158491010.019
positive regulation of cytokine productionGO:00018191740.019
cellular response to organonitrogen compoundGO:00714171450.019
dicarboxylic acid metabolic processGO:0043648180.019
protein localization to membraneGO:00726571080.019
regulation of cytoplasmic transportGO:19036491120.019
cellular amino acid catabolic processGO:0009063250.019
fatty acid beta oxidationGO:0006635160.019
endomembrane system organizationGO:00102561470.019
glycerophospholipid metabolic processGO:0006650710.019
coenzyme a biosynthetic processGO:001593750.019
monosaccharide metabolic processGO:00059961060.019
regulation of protein import into nucleusGO:0042306520.019
cation transmembrane transportGO:00986552660.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
homeostasis of number of cellsGO:00488722100.019
Mouse
positive regulation of protein phosphorylationGO:00019342420.019
positive regulation of programmed cell deathGO:00430682180.019
protein importGO:00170381010.019
regulation of cellular response to stressGO:00801351590.018
nucleotide biosynthetic processGO:0009165780.018
paracrine signalingGO:003800110.018
axonogenesisGO:00074092740.018
nucleoside phosphate metabolic processGO:00067533380.018
small gtpase mediated signal transductionGO:0007264970.018
calcium ion homeostasisGO:00550741270.018
nucleoside bisphosphate metabolic processGO:003386590.018
sensory organ morphogenesisGO:00905962420.018
purine containing compound metabolic processGO:00725213110.018
hematopoietic progenitor cell differentiationGO:00022441430.018
skin developmentGO:00435882200.018
divalent metal ion transportGO:00708381720.018
lipid transportGO:0006869980.018
divalent inorganic cation homeostasisGO:00725071380.018
regulation of transmembrane transportGO:00347621280.018
response to molecule of bacterial originGO:00022371430.018
sterol homeostasisGO:0055092450.017
monosaccharide biosynthetic processGO:0046364440.017
male gamete generationGO:00482322850.017
cytokine mediated signaling pathwayGO:00192211150.017
nucleoside phosphate biosynthetic processGO:1901293790.017
ras protein signal transductionGO:0007265770.017
cellular nitrogen compound catabolic processGO:00442702800.017
monocarboxylic acid catabolic processGO:0072329270.017
aromatic compound catabolic processGO:00194392860.017
regulation of sequence specific dna binding transcription factor activityGO:00510901060.017
organic hydroxy compound catabolic processGO:1901616250.017
myeloid leukocyte differentiationGO:00025731190.017
Mouse
response to organonitrogen compoundGO:00102432460.017
regulation of cell activationGO:00508652890.017
monocarboxylic acid biosynthetic processGO:0072330610.017
divalent inorganic cation transportGO:00725111780.017
immune effector processGO:00022523210.017
cellular calcium ion homeostasisGO:00068741190.017
regulation of intracellular protein transportGO:0033157820.016
sphingolipid biosynthetic processGO:0030148260.016
positive regulation of apoptotic processGO:00430652170.016
response to extracellular stimulusGO:00099911270.016
muscle cell differentiationGO:00426922610.016
regulation of membrane potentialGO:00423911920.016
negative regulation of intracellular signal transductionGO:19025321670.016
regulation of response to woundingGO:19030341890.016
response to nutrient levelsGO:00316671090.016
endocytosisGO:00068971680.016
single organism nuclear importGO:1902593950.016
nuclear importGO:0051170950.016
regulation of mapk cascadeGO:00434082480.016
nucleoside metabolic processGO:00091162460.016
cell type specific apoptotic processGO:00972852680.016
cellular response to hormone stimulusGO:00328701500.016
heart morphogenesisGO:00030071780.016
ear developmentGO:00435832000.016
morphogenesis of embryonic epitheliumGO:00163311590.016
lipid modificationGO:0030258650.016
establishment of protein localization to organelleGO:00725941180.016
cell adhesionGO:00071553290.016
alpha amino acid metabolic processGO:1901605590.016
camera type eye developmentGO:00430102660.015
synaptic transmissionGO:00072683290.015
striated muscle tissue developmentGO:00147062930.015
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.015
chromatin modificationGO:00165681870.015
purine ribonucleotide biosynthetic processGO:0009152590.015
regulation of multi organism processGO:00439001110.015
carboxylic acid transportGO:00469421000.015
response to acid chemicalGO:00011011110.015
positive regulation of apoptotic signaling pathwayGO:2001235950.015
purine ribonucleoside biosynthetic processGO:0046129190.015
ribonucleotide biosynthetic processGO:0009260590.015
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.015
muscle tissue developmentGO:00605373080.015
cognitionGO:00508901490.015
cellular macromolecule catabolic processGO:00442652060.015
glycosyl compound metabolic processGO:19016572460.015
posttranscriptional regulation of gene expressionGO:00106081550.015
development of primary sexual characteristicsGO:00451371430.015
regulation of lymphocyte activationGO:00512492400.015
regulation of secretion by cellGO:19035302490.015
negative regulation of immune system processGO:00026832090.015
sulfur compound biosynthetic processGO:0044272370.015
epithelial cell developmentGO:00020641590.015
carbohydrate biosynthetic processGO:0016051740.014
tumor necrosis factor productionGO:0032640500.014
cell junction maintenanceGO:003433140.014
coenzyme a metabolic processGO:001593680.014
negative regulation of multi organism processGO:0043901680.014
protein oligomerizationGO:0051259670.014
macromolecule catabolic processGO:00090572810.014
lipid storageGO:0019915360.014
regulation of protein import into nucleus translocationGO:003315820.014
defense response to bacteriumGO:00427421190.014
protein maturationGO:00516041760.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
ribonucleotide metabolic processGO:00092592910.014
rho protein signal transductionGO:0007266320.014
cellular response to lipopolysaccharideGO:0071222770.014
chemokine productionGO:0032602340.014
regulation of nucleocytoplasmic transportGO:0046822730.014
positive regulation of intracellular transportGO:0032388700.014
response to copper ionGO:004668830.014
multicellular organismal signalingGO:0035637910.014
regulation of homeostatic processGO:00328441820.014
response to uvGO:0009411440.014
cellularizationGO:000734910.014
regulation of secretionGO:00510462740.014
positive regulation of cell developmentGO:00107202370.013
positive regulation of lipid biosynthetic processGO:0046889180.013
very long chain fatty acid catabolic processGO:004276020.013
hair cycleGO:0042633900.013
action potentialGO:0001508780.013
steroid biosynthetic processGO:0006694470.013
g protein coupled receptor signaling pathwayGO:00071862430.013
muscle system processGO:00030121410.013
response to hydrogen peroxideGO:0042542320.013
positive regulation of protein transportGO:0051222930.013
alcohol biosynthetic processGO:0046165430.013
immune response regulating signaling pathwayGO:00027641250.013
negative regulation of protein metabolic processGO:00512482820.013
regulation of cellular response to oxidative stressGO:1900407190.013
protein ubiquitinationGO:00165671710.013
cellular amide metabolic processGO:0043603580.013
mapk cascadeGO:00001652810.013
liver developmentGO:0001889660.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
regulation of hydrolase activityGO:00513362460.013
locomotory behaviorGO:00076261950.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.013
skeletal system developmentGO:00015013560.013
organic hydroxy compound biosynthetic processGO:1901617770.013
blood vessel morphogenesisGO:00485142850.013
multicellular organismal homeostasisGO:00488711640.013
cellular response to gamma radiationGO:007148040.013
epithelial tube morphogenesisGO:00605623030.013
positive regulation of type i interferon mediated signaling pathwayGO:006034040.013
i kappab kinase nf kappab signalingGO:0007249850.013
peptide metabolic processGO:0006518460.013
nucleotide catabolic processGO:00091662170.012
cellular response to acid chemicalGO:0071229680.012
triglyceride biosynthetic processGO:0019432170.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
regulation of protein kinase activityGO:00458592320.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.012
forebrain developmentGO:00309003020.012
protein targeting to vacuoleGO:000662330.012
negative regulation of cell proliferationGO:00082852960.012
response to superoxideGO:0000303160.012
dna metabolic processGO:00062593030.012
regulation of myotube differentiationGO:0010830620.012
nucleoside biosynthetic processGO:0009163210.012
skeletal muscle organ developmentGO:00605381630.012
positive regulation of defense responseGO:00313491240.012
protein import into nucleusGO:0006606950.012
multicellular organism growthGO:00352641610.012
myotube differentiationGO:00149021050.012
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.012
regulation of tumor necrosis factor productionGO:0032680490.012
germ cell developmentGO:00072811850.012
epithelial cell proliferationGO:00506731740.012
defecationGO:003042110.012
activation of immune responseGO:00022531380.012
negative regulation of phosphate metabolic processGO:00459361840.012
tumor necrosis factor superfamily cytokine productionGO:0071706510.012
regulation of transcription factor import into nucleusGO:0042990240.012
cellular response to molecule of bacterial originGO:0071219830.012
positive regulation of growthGO:00459271040.012
phosphatidylinositol mediated signalingGO:0048015410.012
adult behaviorGO:00305341350.012
regulation of phosphatidylcholine catabolic processGO:001089920.012
cellular response to biotic stimulusGO:0071216920.012
lateral inhibitionGO:004633110.012
vesicle localizationGO:0051648860.011
spermatid developmentGO:00072861080.011
regulation of striated muscle cell differentiationGO:0051153810.011
inflammatory responseGO:00069542440.011
negative regulation of cellular component organizationGO:00511291940.011
sequestering of calcium ionGO:0051208180.011
methylationGO:00322591340.011
morphogenesis of a branching structureGO:00017632030.011
sodium ion transportGO:0006814730.011
positive regulation of cholesterol storageGO:001088630.011
neutral lipid biosynthetic processGO:0046460180.011
single organism cell adhesionGO:00986021560.011
immune response activating signal transductionGO:00027571160.011
inositol lipid mediated signalingGO:0048017410.011
ceramide metabolic processGO:0006672310.011
cell cell junction organizationGO:0045216720.011
negative regulation of organelle organizationGO:0010639900.011
calcium ion transportGO:00068161590.011
c21 steroid hormone biosynthetic processGO:000670030.011
lymphocyte proliferationGO:00466511640.011
regulation of protein targetingGO:1903533610.011
response to lipopolysaccharideGO:00324961280.011
intracellular mrna localizationGO:000829840.011
regulation of neuron differentiationGO:00456642810.011
blood circulationGO:00080151950.011
anatomical structure homeostasisGO:00602491450.011
hormone metabolic processGO:0042445860.011
protein catabolic processGO:00301632210.011
glucose metabolic processGO:0006006920.011
oocyte constructionGO:000730820.011
regulation of lipid metabolic processGO:00192161180.011
morphogenesis of a branching epitheliumGO:00611381930.011
regulation of purine nucleotide metabolic processGO:19005421690.011
regulation of chemokine productionGO:0032642300.011
kidney developmentGO:00018222130.011
hexose metabolic processGO:0019318980.011
respiratory system developmentGO:00605411900.011
cholesterol storageGO:001087840.011
regulation of proteolysisGO:00301621640.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
nucleoside phosphate catabolic processGO:19012922220.011
urogenital system developmentGO:00016552610.011
positive regulation of nf kappab transcription factor activityGO:0051092300.011
regulation of cell cycleGO:00517262810.011
membrane lipid metabolic processGO:0006643530.011
pyridine containing compound catabolic processGO:007252640.011
regulation of interleukin 8 secretionGO:200048220.011
positive regulation of nucleotide metabolic processGO:00459811140.011
response to peptide hormoneGO:00434341270.010
positive regulation of tumor necrosis factor productionGO:0032760300.010
organophosphate catabolic processGO:00464342320.010
cellular protein complex assemblyGO:00436231160.010
adiponectin activated signaling pathwayGO:003321140.010
cellular aldehyde metabolic processGO:0006081120.010
neural tube developmentGO:00219151600.010
male sex differentiationGO:00466611090.010
regulation of transferase activityGO:00513382630.010
tube formationGO:00351481400.010
sodium ion transmembrane transportGO:0035725490.010
digestive system developmentGO:00551232000.010
hydrogen peroxide metabolic processGO:0042743160.010
regulation of leukocyte differentiationGO:19021051590.010
negative regulation of phosphorus metabolic processGO:00105631840.010
polyol metabolic processGO:0019751260.010
transmission of nerve impulseGO:0019226760.010
response to hydroperoxideGO:003319460.010
ear morphogenesisGO:00424711180.010
purine ribonucleoside metabolic processGO:00461282410.010
spermatid differentiationGO:00485151150.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
amide transportGO:00428861380.010
cellular response to peptideGO:1901653920.010
circulatory system processGO:00030131970.010
carbohydrate homeostasisGO:00335001280.010
epidermis developmentGO:00085441870.010
dna repairGO:00062811070.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
regulation of cellular component biogenesisGO:00440871810.010
metal ion homeostasisGO:00550651890.010
covalent chromatin modificationGO:00165691630.010
fat cell differentiationGO:00454441600.010
sphingolipid metabolic processGO:0006665450.010

Aco1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.223
inherited metabolic disorderDOID:65500.093
disease of cellular proliferationDOID:1456600.036
cancerDOID:16200.033
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
organ system cancerDOID:005068600.017
retinal diseaseDOID:567900.017
sensory system diseaseDOID:005015500.017
eye diseaseDOID:561400.017
eye and adnexa diseaseDOID:149200.017
central nervous system diseaseDOID:33100.011