Mus musculus

7 known processes

Lrp1b

low density lipoprotein-related protein 1B (deleted in tumors)

(Aliases: 9630004P12Rik,LRP-DIT)

Lrp1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of membrane potentialGO:00423911920.485
terminal button organizationGO:007255330.399
regulation of ion transmembrane transporter activityGO:0032412540.369
ion transmembrane transportGO:00342203610.347
g protein coupled receptor signaling pathwayGO:00071862430.317
regulation of glutamate receptor signaling pathwayGO:1900449160.317
learningGO:0007612980.284
transmembrane transportGO:00550854120.268
regulation of postsynaptic membrane potentialGO:0060078480.255
glial cell differentiationGO:00100011310.249
Mouse
regulation of transmembrane transportGO:00347621280.207
regulation of synaptic transmission glutamatergicGO:0051966190.197
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activityGO:2000311110.185
synaptic transmissionGO:00072683290.184
neuron neuron synaptic transmissionGO:0007270690.171
fear responseGO:0042596330.166
regulation of ion transmembrane transportGO:00347651190.160
response to organic cyclic compoundGO:00140701980.159
Mouse
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.155
regulation of n methyl d aspartate selective glutamate receptor activityGO:2000310100.151
regulation of transferase activityGO:00513382630.148
Mouse
stem cell differentiationGO:00488632680.125
Mouse
regulation of terminal button organizationGO:200033110.122
action potentialGO:0001508780.117
regulation of excitatory postsynaptic membrane potentialGO:0060079410.114
membrane depolarizationGO:0051899640.100
synaptic transmission glutamatergicGO:0035249360.097
stem cell developmentGO:00488642190.094
Mouse
protein localization to membraneGO:00726571080.094
Mouse
carbohydrate derivative catabolic processGO:19011362310.088
regulation of transporter activityGO:0032409570.088
nucleoside metabolic processGO:00091162460.087
fertilizationGO:00095661270.086
purine ribonucleoside triphosphate catabolic processGO:00092071990.086
myelinationGO:0042552740.085
learning or memoryGO:00076111480.085
glial cell developmentGO:0021782540.082
multicellular organismal response to stressGO:0033555620.082
ribonucleotide metabolic processGO:00092592910.078
positive regulation of kinase activityGO:00336741550.077
Mouse
heterocycle catabolic processGO:00467002800.077
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.076
axon transport of mitochondrionGO:001989620.074
neuronal action potentialGO:0019228540.073
positive regulation of cellular catabolic processGO:00313311480.072
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.071
regulation of ion transportGO:00432692150.069
purine ribonucleoside metabolic processGO:00461282410.068
glycosyl compound catabolic processGO:19016582060.067
nucleoside triphosphate catabolic processGO:00091432050.067
organonitrogen compound catabolic processGO:19015652640.066
nucleoside phosphate metabolic processGO:00067533380.065
cognitionGO:00508901490.065
social behaviorGO:0035176210.064
axon ensheathmentGO:0008366760.063
intrinsic apoptotic signaling pathwayGO:00971931320.063
cell adhesionGO:00071553290.062
purine ribonucleotide metabolic processGO:00091502900.062
regulation of actin nucleationGO:005112540.058
nucleotide metabolic processGO:00091173320.058
mapk cascadeGO:00001652810.058
Mouse
cellular amino acid metabolic processGO:00065201030.058
axonogenesisGO:00074092740.057
Mouse
cation homeostasisGO:00550802120.057
cellular homeostasisGO:00197252400.056
Mouse
single fertilizationGO:0007338820.055
nucleoside phosphate catabolic processGO:19012922220.055
nucleotide catabolic processGO:00091662170.053
transmission of nerve impulseGO:0019226760.052
microtubule based processGO:00070172360.051
digestive tract developmentGO:00485651900.051
Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.051
exocytosisGO:00068871210.050
telencephalon developmentGO:00215371860.050
Mouse
regulation of cellular amino acid metabolic processGO:000652150.050
membrane organizationGO:00610242450.049
Mouse
cellular nitrogen compound catabolic processGO:00442702800.048
small gtpase mediated signal transductionGO:0007264970.047
negative regulation of cellular protein metabolic processGO:00322692470.047
negative regulation of apoptotic signaling pathwayGO:20012341040.046
ribonucleoside metabolic processGO:00091192450.046
purine nucleotide metabolic processGO:00061633020.045
purine nucleoside triphosphate metabolic processGO:00091442260.045
macromolecule catabolic processGO:00090572810.045
Mouse
multi organism behaviorGO:0051705620.044
nucleoside catabolic processGO:00091642060.044
purine nucleoside metabolic processGO:00422782410.044
ribonucleoside catabolic processGO:00424542060.043
adult locomotory behaviorGO:0008344910.043
purine ribonucleoside triphosphate metabolic processGO:00092052200.043
regulation of receptor activityGO:0010469410.042
ribose phosphate metabolic processGO:00196932910.041
behavioral fear responseGO:0001662280.041
ras protein signal transductionGO:0007265770.040
intraspecies interaction between organismsGO:0051703210.040
aromatic compound catabolic processGO:00194392860.039
apoptotic signaling pathwayGO:00971903060.039
regulation of mapk cascadeGO:00434082480.038
Mouse
purine ribonucleoside catabolic processGO:00461302050.038
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.037
cellular chemical homeostasisGO:00550822150.037
Mouse
cellular ketone metabolic processGO:0042180840.037
protein catabolic processGO:00301632210.037
Mouse
response to organonitrogen compoundGO:00102432460.036
Mouse
multicellular organismal signalingGO:0035637910.036
negative regulation of phosphate metabolic processGO:00459361840.036
regulation of cellular catabolic processGO:00313292420.036
Mouse
purine containing compound catabolic processGO:00725232130.036
multicellular organism growthGO:00352641610.035
purine ribonucleotide catabolic processGO:00091542080.035
regulation of hydrolase activityGO:00513362460.035
Mouse
regulation of actin filament based processGO:0032970990.035
Mouse
multi multicellular organism processGO:00447061090.034
angiogenesisGO:00015252010.034
Mouse
regulation of protein kinase activityGO:00458592320.034
Mouse
calcium ion dependent exocytosisGO:0017156350.034
organic cyclic compound catabolic processGO:19013612950.034
regulation of cell adhesionGO:00301551540.033
sa node cell action potentialGO:008601540.033
purine containing compound metabolic processGO:00725213110.033
sensory perception of mechanical stimulusGO:00509541070.033
locomotory behaviorGO:00076261950.033
establishment of glial blood brain barrierGO:006085720.033
inorganic ion transmembrane transportGO:00986602340.032
wnt signaling pathwayGO:00160551880.032
Mouse
dendrite developmentGO:00163581150.031
regulation of apoptotic signaling pathwayGO:20012331970.031
intracellular protein transportGO:00068862040.031
Mouse
amino acid transportGO:0006865610.031
amino acid transmembrane transportGO:0003333370.031
mesodermal cell migrationGO:000807840.030
ribonucleoside triphosphate metabolic processGO:00091992200.030
protein localization to juxtaparanode region of axonGO:007120540.030
response to extracellular stimulusGO:00099911270.029
Mouse
regulation of cellular component biogenesisGO:00440871810.028
skeletal system morphogenesisGO:00487052030.028
Mouse
negative regulation of intracellular signal transductionGO:19025321670.028
regulation of purine nucleotide metabolic processGO:19005421690.028
male gamete generationGO:00482322850.028
actin polymerization or depolymerizationGO:0008154540.027
purine nucleotide catabolic processGO:00061952110.027
cardiocyte differentiationGO:0035051870.027
Mouse
synaptic vesicle transportGO:0048489570.026
organic hydroxy compound transportGO:0015850930.026
Mouse
arp2 3 complex mediated actin nucleationGO:003431430.026
skeletal system developmentGO:00015013560.026
Mouse
germ cell developmentGO:00072811850.026
inorganic cation transmembrane transportGO:00986622070.026
ensheathment of neuronsGO:0007272760.026
organophosphate catabolic processGO:00464342320.026
blood vessel morphogenesisGO:00485142850.026
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.026
ameboidal type cell migrationGO:00016671280.025
Mouse
matingGO:0007618270.025
tissue remodelingGO:00487711020.025
Mouse
chemotaxisGO:00069352470.025
circulatory system processGO:00030131970.025
oocyte constructionGO:000730820.025
regulation of exocytosisGO:0017157610.024
heart morphogenesisGO:00030071780.024
Mouse
cellular response to organonitrogen compoundGO:00714171450.024
regulation of secretionGO:00510462740.024
Mouse
ribonucleotide catabolic processGO:00092612080.024
endocytosisGO:00068971680.024
sa node cell to atrial cardiac muscle cell signallingGO:008601840.024
regulation of defense responseGO:00313472330.024
positive regulation of purine nucleotide metabolic processGO:19005441140.024
vesicle localizationGO:0051648860.024
nucleoside triphosphate metabolic processGO:00091412300.024
protein maturationGO:00516041760.024
purine nucleoside catabolic processGO:00061522050.024
regulation of vesicle mediated transportGO:00606271390.024
regulation of protein complex assemblyGO:0043254830.024
behavioral defense responseGO:0002209280.024
amine metabolic processGO:0009308450.023
regulation of anatomical structure sizeGO:00900661780.023
protein targetingGO:00066051430.023
Mouse
stress activated mapk cascadeGO:0051403800.023
positive regulation of cell adhesionGO:0045785800.023
monoamine transportGO:0015844330.023
transforming growth factor beta receptor signaling pathwayGO:0007179710.023
posttranscriptional regulation of gene expressionGO:00106081550.023
positive regulation of proteolysisGO:0045862850.023
Mouse
cellular ion homeostasisGO:00068731650.023
negative regulation of cellular component organizationGO:00511291940.023
Mouse
regulation of neuron projection developmentGO:00109751690.023
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
positive regulation of transferase activityGO:00513471670.022
Mouse
cell maturationGO:00484691270.022
peptide metabolic processGO:0006518460.022
response to light stimulusGO:00094161350.022
muscle system processGO:00030121410.021
synapse organizationGO:00508081250.021
Mouse
cytoskeleton dependent intracellular transportGO:0030705500.021
telencephalon cell migrationGO:0022029550.021
Mouse
regulation of multi organism processGO:00439001110.021
anion transmembrane transportGO:0098656710.021
organic acid transportGO:00158491010.021
establishment of organelle localizationGO:00516561220.021
bone developmentGO:00603481200.020
Mouse
central nervous system neuron differentiationGO:00219531620.020
cardiac muscle tissue developmentGO:00487381300.020
Mouse
sensory perception of soundGO:0007605970.020
mesenchyme developmentGO:00604851520.020
Mouse
spermatid developmentGO:00072861080.020
establishment of synaptic vesicle localizationGO:0097480570.020
inflammatory responseGO:00069542440.019
cardiac ventricle developmentGO:0003231830.019
Mouse
positive regulation of gtpase activityGO:0043547850.019
cardiac muscle cell contractionGO:008600370.019
regulation of blood vessel sizeGO:0050880560.019
jnk cascadeGO:0007254720.019
blood circulationGO:00080151950.019
gliogenesisGO:00420631410.019
Mouse
positive regulation of nucleoside metabolic processGO:0045979910.019
positive regulation of protein catabolic processGO:0045732600.019
Mouse
heart processGO:0003015940.019
forebrain cell migrationGO:0021885580.018
Mouse
positive regulation of mapk cascadeGO:00434101700.018
Mouse
regulation of kinase activityGO:00435492490.018
Mouse
spermatogenesisGO:00072832840.018
pole plasm assemblyGO:000731520.018
visual learningGO:0008542440.018
regulation of stress activated mapk cascadeGO:0032872690.018
intrinsic apoptotic signaling pathway in response to osmotic stressGO:000862720.018
regulation of nucleoside metabolic processGO:00091181300.018
nerve maturationGO:002168210.018
microtubule based transportGO:0010970500.018
postsynaptic membrane organizationGO:0001941180.018
Mouse
neuromuscular processGO:0050905990.018
long term synaptic depressionGO:0060292130.017
anion transportGO:00068201770.017
reflexGO:0060004220.017
placenta developmentGO:00018901400.017
reproductive behaviorGO:0019098320.017
morphogenesis of a branching epitheliumGO:00611381930.017
Mouse
actin cytoskeleton organizationGO:00300362200.017
Mouse
ventricular cardiac muscle cell action potentialGO:008600540.017
blastocyst developmentGO:0001824800.017
synaptic vesicle localizationGO:0097479590.017
mesenchymal cell differentiationGO:00487621070.017
Mouse
response to starvationGO:0042594650.017
cellular response to transforming growth factor beta stimulusGO:0071560880.017
regulation of organ morphogenesisGO:20000271440.017
Mouse
glucose homeostasisGO:00425931280.016
Mouse
anatomical structure homeostasisGO:00602491450.016
Mouse
regulation of neuron differentiationGO:00456642810.016
Mouse
regulation of epithelial cell proliferationGO:00506781410.016
Mouse
sensory perceptionGO:00076002450.016
regulation of arp2 3 complex mediated actin nucleationGO:003431510.016
oocyte axis specificationGO:000730920.016
embryonic organ morphogenesisGO:00485622760.016
Mouse
peptidyl amino acid modificationGO:00181933360.016
Mouse
vesicle fusionGO:0006906160.016
sulfur compound metabolic processGO:00067901000.016
sperm egg recognitionGO:0035036370.016
regulation of reproductive processGO:2000241660.016
microtubule cytoskeleton organizationGO:00002261570.015
organonitrogen compound biosynthetic processGO:19015661920.015
negative regulation of bone trabecula formationGO:190015510.015
stress activated protein kinase signaling cascadeGO:0031098810.015
membrane biogenesisGO:0044091120.015
Mouse
regulation of nucleotide metabolic processGO:00061401690.015
anterograde synaptic vesicle transportGO:0048490150.015
regulation of cardiac chamber morphogenesisGO:190121920.015
Mouse
cellular response to peptide hormone stimulusGO:0071375920.015
regulation of synaptic plasticityGO:0048167870.015
regulation of actin filament polymerizationGO:0030833380.015
metencephalon developmentGO:0022037890.015
Mouse
regulation of presynaptic membrane organizationGO:190162930.015
Mouse
respiratory system developmentGO:00605411900.015
Mouse
positive regulation of protein kinase activityGO:00458601440.015
Mouse
actin filament organizationGO:00070151130.015
regulation of wnt signaling pathwayGO:00301111230.014
Mouse
regulation of map kinase activityGO:00434051200.014
Mouse
neuromuscular process controlling balanceGO:0050885590.014
membrane fusionGO:0061025380.014
striated muscle contractionGO:0006941450.014
positive regulation of protein complex assemblyGO:0031334450.014
endomembrane system organizationGO:00102561470.014
positive regulation of purine nucleotide catabolic processGO:0033123880.014
regulation of protein serine threonine kinase activityGO:00719001570.014
Mouse
regulation of response to drugGO:200102320.014
rna processingGO:00063961050.014
positive regulation of cell motilityGO:20001471160.014
hexose transportGO:0008645560.014
positive regulation of nucleotide catabolic processGO:0030813880.014
bone resorptionGO:0045453380.014
Mouse
regulation of actin cytoskeleton organizationGO:0032956840.014
Mouse
l amino acid transportGO:0015807320.014
olfactory learningGO:000835520.014
carbohydrate derivative biosynthetic processGO:19011371830.014
positive regulation of gtp catabolic processGO:0033126850.014
mating behaviorGO:0007617200.014
habituationGO:004695930.013
forebrain developmentGO:00309003020.013
Mouse
rho protein signal transductionGO:0007266320.013
glucose transportGO:0015758560.013
cellular amine metabolic processGO:0044106440.013
cellular response to organic cyclic compoundGO:0071407870.013
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.013
monosaccharide transportGO:0015749580.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
adult behaviorGO:00305341350.013
regulation of protein catabolic processGO:00421761080.013
Mouse
regulation of organelle organizationGO:00330432890.013
Mouse
single organism cell adhesionGO:00986021560.013
spermatid differentiationGO:00485151150.013
gtp metabolic processGO:00460391440.013
protein processingGO:00164851630.013
presynaptic membrane assemblyGO:009710570.013
Mouse
multi organism reproductive behaviorGO:0044705290.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.013
hindbrain developmentGO:00309021280.013
Mouse
regulation of blood circulationGO:1903522930.013
regulation of feeding behaviorGO:006025930.013
conditioned taste aversionGO:000166140.013
membrane depolarization during sa node cell action potentialGO:008604620.013
pallium developmentGO:00215431200.013
Mouse
defecationGO:003042110.013
negative regulation of neuron apoptotic processGO:0043524920.013
leukocyte migrationGO:00509001240.013
positive regulation of cellular amine metabolic processGO:003324050.013
carbohydrate transportGO:0008643620.013
divalent inorganic cation homeostasisGO:00725071380.013
carbohydrate metabolic processGO:00059752300.012
cytoplasmic transportGO:00164822340.012
Mouse
formation of radial glial scaffoldsGO:002194340.012
Mouse
regulation of response to woundingGO:19030341890.012
regulation of serotonin secretionGO:001406230.012
negative regulation of mapk cascadeGO:0043409650.012
cell type specific apoptotic processGO:00972852680.012
lipid transportGO:0006869980.012
Mouse
cation transmembrane transportGO:00986552660.012
metal ion homeostasisGO:00550651890.012
oocyte anterior posterior axis specificationGO:000731420.012
positive regulation of nucleotide metabolic processGO:00459811140.012
dendritic spine maintenanceGO:009706240.012
cell growthGO:00160491300.012
positive regulation of ras gtpase activityGO:0032320650.012
leukocyte chemotaxisGO:0030595690.012
muscle contractionGO:00069361010.012
regulation of actin polymerization or depolymerizationGO:0008064450.012
actin filament polymerizationGO:0030041440.012
regulation of cytoskeleton organizationGO:00514931220.012
Mouse
cell recognitionGO:0008037830.012
binding of sperm to zona pellucidaGO:0007339340.012
axon cargo transportGO:0008088330.012
positive regulation of apoptotic processGO:00430652170.012
Mouse
regulation of cellular component sizeGO:00325351210.012
regulation of cellular response to stressGO:00801351590.012
regulation of ossificationGO:00302781120.012
Mouse
negative regulation of cytoskeleton organizationGO:0051494360.012
cellular lipid metabolic processGO:00442553230.012
negative regulation of cell developmentGO:00107211690.012
Mouse
organelle localizationGO:00516401790.012
protein polymerizationGO:0051258570.012
myeloid leukocyte migrationGO:0097529570.012
visual perceptionGO:0007601520.012
regulation of bone remodelingGO:0046850280.012
Mouse
response to growth factorGO:00708481980.012
maternal determination of anterior posterior axis embryoGO:000835820.012
positive regulation of heart rate by epinephrine norepinephrineGO:000199640.012
nitrogen compound transportGO:00717052710.012
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
regulation of nucleotide catabolic processGO:00308111220.011
actin mediated cell contractionGO:0070252150.011
digestive tract morphogenesisGO:00485461470.011
Mouse
positive regulation of membrane protein ectodomain proteolysisGO:005104430.011
regulation of cell motilityGO:20001452360.011
Mouse
glucose importGO:0046323320.011
adult walking behaviorGO:0007628410.011
cellular macromolecule catabolic processGO:00442652060.011
Mouse
neuron projection guidanceGO:00974851410.011
embryonic placenta developmentGO:0001892980.011
response to peptide hormoneGO:00434341270.011
regulation of secretion by cellGO:19035302490.011
Mouse
purine nucleotide biosynthetic processGO:0006164650.011
negative regulation of phosphorylationGO:00423261660.011
gtp catabolic processGO:00061841430.011
glycosyl compound metabolic processGO:19016572460.011
response to oxygen levelsGO:0070482620.011
negative regulation of neuron differentiationGO:00456651010.011
Mouse
detection of stimulusGO:0051606840.011
regulation of jnk cascadeGO:0046328620.011
response to transforming growth factor betaGO:0071559880.011
regulation of protein modification by small protein conjugation or removalGO:1903320570.011
Mouse
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711330.011
clustering of voltage gated potassium channelsGO:004516320.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
cellular response to growth factor stimulusGO:00713631970.011
response to nutrient levelsGO:00316671090.011
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.011
cellular response to lipidGO:00713961450.011
positive regulation of cell migrationGO:00303351090.011
regionalizationGO:00030023370.011
Mouse
neuron migrationGO:00017641220.011
actin filament based movementGO:0030048230.011
morphogenesis of a branching structureGO:00017632030.011
Mouse
maintenance of locationGO:0051235890.011
microtubule based movementGO:0007018840.011
nuclear divisionGO:00002801580.011
protein secretionGO:00093061110.011
positive regulation of organelle organizationGO:00106381280.011
neuron deathGO:00709971540.011
gland developmentGO:00487323300.011
Mouse
response to peptideGO:19016521360.011
neuron apoptotic processGO:00514021420.010
digestive system developmentGO:00551232000.010
Mouse
cerebral cortex cell migrationGO:0021795440.010
Mouse
heart contractionGO:0060047930.010
purine ribonucleoside monophosphate catabolic processGO:0009169570.010
positive regulation of nervous system developmentGO:00519622210.010
Mouse
cardiac septum developmentGO:0003279590.010
Mouse
leukocyte differentiationGO:00025213420.010
cellular response to hormone stimulusGO:00328701500.010
regulation of cellular amine metabolic processGO:0033238200.010
organ growthGO:00352651170.010
vascular process in circulatory systemGO:0003018620.010
organic anion transportGO:00157111370.010
positive regulation of secretionGO:00510471300.010
retina development in camera type eyeGO:00600411190.010
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.010
positive regulation of inositol phosphate biosynthetic processGO:006073220.010
physiological cardiac muscle hypertrophyGO:000330130.010
immune effector processGO:00022523210.010
response to drugGO:0042493750.010

Lrp1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.033
diabetes mellitusDOID:935100.017
type 2 diabetes mellitusDOID:935200.017
carbohydrate metabolism diseaseDOID:005001300.017
glucose metabolism diseaseDOID:419400.017
acquired metabolic diseaseDOID:006015800.017
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012
central nervous system diseaseDOID:33100.010
neurodegenerative diseaseDOID:128900.010