IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Eci2

enoyl-Coenzyme A delta isomerase 2

(Aliases: Acbd2,Hca88,Drs1,Peci)

Entrez: 23986
Ensembl: ENSMUSG00000021417
UniProtKB: Q9WUR2

Process Predictions
Disease Predictions

Eci2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
monocarboxylic acid metabolic process	GO:0032787	191	0.963	Rat
monocarboxylic acid catabolic process	GO:0072329	27	0.960	Rat
cellular lipid catabolic process	GO:0044242	52	0.959	Rat
thioester metabolic process	GO:0035383	19	0.949
fatty acid beta oxidation	GO:0006635	16	0.928	Rat
acyl coa metabolic process	GO:0006637	19	0.925
lipid catabolic process	GO:0016042	69	0.920	Rat
fatty acid oxidation	GO:0019395	28	0.899	Rat
cofactor metabolic process	GO:0051186	80	0.853
lipid oxidation	GO:0034440	29	0.773	Rat
fatty acid catabolic process	GO:0009062	25	0.708	Rat
very long chain fatty acid catabolic process	GO:0042760	2	0.666
organic acid catabolic process	GO:0016054	51	0.655	Rat
cellular lipid metabolic process	GO:0044255	323	0.652	Rat
carboxylic acid catabolic process	GO:0046395	51	0.623	Rat
oxidation reduction process	GO:0055114	342	0.576	Rat
coenzyme metabolic process	GO:0006732	52	0.518
small molecule catabolic process	GO:0044282	71	0.473	Rat
very long chain fatty acid metabolic process	GO:0000038	8	0.465
fatty acid metabolic process	GO:0006631	121	0.454	Rat
lipid modification	GO:0030258	65	0.379	Rat
steroid metabolic process	GO:0008202	119	0.280
carnitine metabolic process	GO:0009437	7	0.246
organic hydroxy compound metabolic process	GO:1901615	203	0.230
regulation of hormone levels	GO:0010817	211	0.227
cellular ketone metabolic process	GO:0042180	84	0.195
sulfur compound metabolic process	GO:0006790	100	0.185
acetyl coa metabolic process	GO:0006084	8	0.184
protein oligomerization	GO:0051259	67	0.163
small molecule biosynthetic process	GO:0044283	132	0.124
organic acid biosynthetic process	GO:0016053	86	0.100
regulation of cellular ketone metabolic process	GO:0010565	66	0.100
protein homooligomerization	GO:0051260	43	0.088
sterol metabolic process	GO:0016125	58	0.080
epithelial cell development	GO:0002064	159	0.079
carboxylic acid biosynthetic process	GO:0046394	86	0.073
hormone metabolic process	GO:0042445	86	0.069
cellular amine metabolic process	GO:0044106	44	0.063
saturated monocarboxylic acid metabolic process	GO:0032788	2	0.060
maintenance of location	GO:0051235	89	0.056
response to molecule of bacterial origin	GO:0002237	143	0.056
innate immune response	GO:0045087	157	0.054
amine metabolic process	GO:0009308	45	0.052
membrane organization	GO:0061024	245	0.050
coenzyme biosynthetic process	GO:0009108	23	0.050
anion transport	GO:0006820	177	0.049
fatty acid alpha oxidation	GO:0001561	2	0.049
lipid biosynthetic process	GO:0008610	179	0.047
regulation of apoptotic signaling pathway	GO:2001233	197	0.040
development of primary male sexual characteristics	GO:0046546	88	0.040
response to lipopolysaccharide	GO:0032496	128	0.040
male gonad development	GO:0008584	88	0.039
defense response to bacterium	GO:0042742	119	0.039
homeostasis of number of cells	GO:0048872	210	0.038
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.038
regulation of cellular amino acid metabolic process	GO:0006521	5	0.038
male sex differentiation	GO:0046661	109	0.036
androgen metabolic process	GO:0008209	11	0.036
protein tetramerization	GO:0051262	23	0.036
mitochondrial outer membrane permeabilization involved in programmed cell death	GO:1902686	11	0.034
alcohol metabolic process	GO:0006066	116	0.033
fatty acyl coa metabolic process	GO:0035337	4	0.033
gonad development	GO:0008406	141	0.033
apoptotic mitochondrial changes	GO:0008637	48	0.033
mitochondrion organization	GO:0007005	134	0.033
response to oxygen levels	GO:0070482	62	0.032
transmembrane transport	GO:0055085	412	0.031
regulation of cellular amine metabolic process	GO:0033238	20	0.031
regulation of intracellular transport	GO:0032386	159	0.030
development of primary sexual characteristics	GO:0045137	143	0.030
cholesterol metabolic process	GO:0008203	56	0.030
negative regulation of cell proliferation	GO:0008285	296	0.029
regulation of fatty acid oxidation	GO:0046320	10	0.029
protein processing	GO:0016485	163	0.029
cofactor biosynthetic process	GO:0051188	41	0.029
response to oxygen radical	GO:0000305	16	0.028
succinyl coa metabolic process	GO:0006104	1	0.028
positive regulation of cellular amine metabolic process	GO:0033240	5	0.028
response to organic cyclic compound	GO:0014070	198	0.028
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.027
nucleoside phosphate metabolic process	GO:0006753	338	0.027
negative regulation of protein metabolic process	GO:0051248	282	0.027
protein maturation	GO:0051604	176	0.026
regulation of lipid metabolic process	GO:0019216	118	0.026
defense response to gram negative bacterium	GO:0050829	28	0.025
monocarboxylic acid biosynthetic process	GO:0072330	61	0.025
lipid localization	GO:0010876	126	0.025
nucleotide metabolic process	GO:0009117	332	0.024
purine ribonucleotide metabolic process	GO:0009150	290	0.024
cellular macromolecule catabolic process	GO:0044265	206	0.024
amino acid betaine metabolic process	GO:0006577	7	0.024
liver development	GO:0001889	66	0.024
ossification	GO:0001503	216	0.024
retinoid metabolic process	GO:0001523	24	0.024
cation transport	GO:0006812	399	0.023
nucleoside metabolic process	GO:0009116	246	0.022
response to organonitrogen compound	GO:0010243	246	0.022
organic anion transport	GO:0015711	137	0.022
defense response to other organism	GO:0098542	197	0.022
negative regulation of cellular protein metabolic process	GO:0032269	247	0.022
acylglycerol metabolic process	GO:0006639	55	0.022
organic cyclic compound catabolic process	GO:1901361	295	0.021
response to hypoxia	GO:0001666	58	0.021
response to epidermal growth factor	GO:0070849	4	0.021
cellular nitrogen compound catabolic process	GO:0044270	280	0.020
regulation of mitochondrion organization	GO:0010821	27	0.020
cellular response to lipid	GO:0071396	145	0.019
nucleobase containing small molecule metabolic process	GO:0055086	352	0.019
ion transmembrane transport	GO:0034220	361	0.019
cell type specific apoptotic process	GO:0097285	268	0.019
regulation of organelle organization	GO:0033043	289	0.019
renal system development	GO:0072001	225	0.019
progesterone metabolic process	GO:0042448	4	0.019
response to decreased oxygen levels	GO:0036293	59	0.018
positive regulation of protein modification process	GO:0031401	299	0.018
reactive nitrogen species metabolic process	GO:2001057	0	0.018
aromatic compound catabolic process	GO:0019439	286	0.018
regulation of protein kinase activity	GO:0045859	232	0.018
purine nucleoside metabolic process	GO:0042278	241	0.018
diterpenoid metabolic process	GO:0016101	24	0.018
inflammatory response	GO:0006954	244	0.017
carbohydrate derivative catabolic process	GO:1901136	231	0.017
positive regulation of mitochondrial membrane permeability	GO:0035794	12	0.017
regulation of kinase activity	GO:0043549	249	0.017
ethanol metabolic process	GO:0006067	3	0.017
response to nutrient levels	GO:0031667	109	0.017
pyruvate transport	GO:0006848	2	0.017
negative regulation of cellular component organization	GO:0051129	194	0.017
isoprenoid metabolic process	GO:0006720	29	0.017
leukocyte differentiation	GO:0002521	342	0.017
regulation of cellular catabolic process	GO:0031329	242	0.017
action potential	GO:0001508	78	0.017
purine ribonucleotide catabolic process	GO:0009154	208	0.017
spermatogenesis	GO:0007283	284	0.017
negative regulation of protein processing	GO:0010955	79	0.016
kidney development	GO:0001822	213	0.016
purine nucleotide catabolic process	GO:0006195	211	0.016
cellular amino acid metabolic process	GO:0006520	103	0.016
apoptotic signaling pathway	GO:0097190	306	0.016
response to starvation	GO:0042594	65	0.016
cytoplasmic transport	GO:0016482	234	0.016
regulation of secretion	GO:0051046	274	0.016
fatty acid biosynthetic process	GO:0006633	41	0.016
purine containing compound catabolic process	GO:0072523	213	0.015
estrogen metabolic process	GO:0008210	8	0.015
protein homotetramerization	GO:0051289	12	0.015
sulfur compound biosynthetic process	GO:0044272	37	0.015
cellular homeostasis	GO:0019725	240	0.015
cellular response to oxidative stress	GO:0034599	76	0.015
endomembrane system organization	GO:0010256	147	0.015
response to steroid hormone	GO:0048545	56	0.015
microtubule based process	GO:0007017	236	0.015
macromolecule catabolic process	GO:0009057	281	0.015
positive regulation of protein phosphorylation	GO:0001934	242	0.015
ribonucleoside metabolic process	GO:0009119	245	0.015
regulation of response to wounding	GO:1903034	189	0.014
synaptic transmission	GO:0007268	329	0.014
cellular ion homeostasis	GO:0006873	165	0.014
neuron death	GO:0070997	154	0.014
regulation of membrane potential	GO:0042391	192	0.014
cellular amide metabolic process	GO:0043603	58	0.014
cellular modified amino acid metabolic process	GO:0006575	63	0.014
mitochondrial transport	GO:0006839	36	0.014
gland development	GO:0048732	330	0.014
positive regulation of cell death	GO:0010942	224	0.014
reactive oxygen species metabolic process	GO:0072593	84	0.014
transmission of nerve impulse	GO:0019226	76	0.014
metal ion homeostasis	GO:0055065	189	0.014
response to drug	GO:0042493	75	0.014
negative regulation of protein maturation	GO:1903318	79	0.013
negative regulation of organelle organization	GO:0010639	90	0.013
cellular response to oxygen radical	GO:0071450	14	0.013
negative regulation of intracellular transport	GO:0032387	38	0.013
negative regulation of phosphate metabolic process	GO:0045936	184	0.013
nitrogen compound transport	GO:0071705	271	0.013
organophosphate catabolic process	GO:0046434	232	0.013
cellular alcohol biosynthetic process	GO:0044108	3	0.013
ribose phosphate metabolic process	GO:0019693	291	0.013
ribonucleotide catabolic process	GO:0009261	208	0.013
purine nucleotide metabolic process	GO:0006163	302	0.013
triglyceride metabolic process	GO:0006641	51	0.013
endocytosis	GO:0006897	168	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013
cellular response to organonitrogen compound	GO:0071417	145	0.013
regulation of secretion by cell	GO:1903530	249	0.013
multicellular organismal signaling	GO:0035637	91	0.012
purine ribonucleoside metabolic process	GO:0046128	241	0.012
response to inorganic substance	GO:0010035	96	0.012
inorganic cation transmembrane transport	GO:0098662	207	0.012
purine containing compound metabolic process	GO:0072521	311	0.012
negative regulation of immune system process	GO:0002683	209	0.012
nucleocytoplasmic transport	GO:0006913	139	0.012
cation homeostasis	GO:0055080	212	0.012
cellular response to biotic stimulus	GO:0071216	92	0.012
fat cell differentiation	GO:0045444	160	0.012
extracellular structure organization	GO:0043062	148	0.012
peptidyl amino acid modification	GO:0018193	336	0.012
glycerophospholipid metabolic process	GO:0006650	71	0.012
male gamete generation	GO:0048232	285	0.012
regulation of transferase activity	GO:0051338	263	0.012
regulation of body fluid levels	GO:0050878	162	0.012
positive regulation of secretion by cell	GO:1903532	114	0.012
cellular response to molecule of bacterial origin	GO:0071219	83	0.012
phospholipid metabolic process	GO:0006644	87	0.012
negative regulation of molecular function	GO:0044092	258	0.012
nucleotide catabolic process	GO:0009166	217	0.012
energy derivation by oxidation of organic compounds	GO:0015980	77	0.012
cellular aldehyde metabolic process	GO:0006081	12	0.012
regulation of fatty acid beta oxidation	GO:0031998	1	0.012
organic hydroxy compound biosynthetic process	GO:1901617	77	0.012
regulation of cholesterol metabolic process	GO:0090181	14	0.012
regulation of neuron death	GO:1901214	134	0.012
circulatory system process	GO:0003013	197	0.012
organonitrogen compound biosynthetic process	GO:1901566	192	0.012
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.012
generation of precursor metabolites and energy	GO:0006091	103	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.012
organic hydroxy compound transport	GO:0015850	93	0.012
negative regulation of fatty acid metabolic process	GO:0045922	10	0.011
regulation of cell activation	GO:0050865	289	0.011
response to extracellular stimulus	GO:0009991	127	0.011
response to oxidative stress	GO:0006979	123	0.011
regulation of cytokine production	GO:0001817	266	0.011
striated muscle tissue development	GO:0014706	293	0.011
cytokine production	GO:0001816	319	0.011
hematopoietic progenitor cell differentiation	GO:0002244	143	0.011
regulation of defense response	GO:0031347	233	0.011
regulation of lymphocyte activation	GO:0051249	240	0.011
response to reactive oxygen species	GO:0000302	56	0.011
porphyrin containing compound metabolic process	GO:0006778	22	0.011
sensory perception	GO:0007600	245	0.011
nucleoside phosphate catabolic process	GO:1901292	222	0.011
protein localization to nucleus	GO:0034504	121	0.011
regulation of phosphatidylcholine catabolic process	GO:0010899	2	0.011
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.011
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.011
protein import	GO:0017038	101	0.011
lipid storage	GO:0019915	36	0.011
divalent inorganic cation homeostasis	GO:0072507	138	0.011
regulation of removal of superoxide radicals	GO:2000121	4	0.011
negative regulation of phosphorus metabolic process	GO:0010563	184	0.011
fatty acid transmembrane transport	GO:1902001	1	0.011
response to metal ion	GO:0010038	47	0.011
skin development	GO:0043588	220	0.011
positive regulation of kinase activity	GO:0033674	155	0.011
neuronal action potential	GO:0019228	54	0.011
immune effector process	GO:0002252	321	0.010
cellular response to hormone stimulus	GO:0032870	150	0.010
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.010
epithelial tube morphogenesis	GO:0060562	303	0.010
regulation of nucleocytoplasmic transport	GO:0046822	73	0.010
water soluble vitamin biosynthetic process	GO:0042364	3	0.010
activation of immune response	GO:0002253	138	0.010
acetate metabolic process	GO:0006083	1	0.010
multicellular organismal homeostasis	GO:0048871	164	0.010
negative regulation of neuron apoptotic process	GO:0043524	92	0.010
citrate metabolic process	GO:0006101	3	0.010
regulation of neuron apoptotic process	GO:0043523	122	0.010
neural tube formation	GO:0001841	108	0.010
hexose metabolic process	GO:0019318	98	0.010
regulation of cellular response to stress	GO:0080135	159	0.010

Eci2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.057
carbohydrate metabolic disorder	DOID:2978	0.023
hyperinsulinemic hypoglycemia	DOID:13317	0.023
inherited metabolic disorder	DOID:655	0.023
disease of anatomical entity	DOID:7	0.015
nervous system disease	DOID:863	0.015

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