Mus musculus

97 known processes

Prmt5

protein arginine N-methyltransferase 5

(Aliases: Jbp1,Skb1)

Prmt5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin disassemblyGO:003149810.957
protein dna complex disassemblyGO:003298610.956
nucleosome disassemblyGO:000633710.944
pole plasm assemblyGO:000731520.543
Fly
chromatin organizationGO:00063252060.391
meiotic nuclear divisionGO:00071261150.281
protein dna complex subunit organizationGO:0071824280.245
regulation of cell cycleGO:00517262810.223
regulation of cell cycle processGO:00105641600.219
oocyte anterior posterior axis specificationGO:000731420.204
Fly
macromolecule methylationGO:00434141200.159
spermatogenesisGO:00072832840.152
male gamete generationGO:00482322850.131
meiotic cell cycleGO:00513211220.113
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.112
nuclear divisionGO:00002801580.097
regulation of mitotic cell cycle phase transitionGO:1901990730.094
positive regulation of mitotic metaphase anaphase transitionGO:004584220.091
apoptotic signaling pathwayGO:00971903060.080
Worm
regionalizationGO:00030023370.079
Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.077
Human
chromatin remodelingGO:0006338320.077
rna splicing via transesterification reactionsGO:0000375430.076
Human
snrna processingGO:001618010.073
negative regulation of cell proliferationGO:00082852960.072
protein complex disassemblyGO:0043241400.070
macromolecular complex disassemblyGO:0032984430.067
mrna splicing via spliceosomeGO:0000398430.059
Human
intrinsic apoptotic signaling pathwayGO:00971931320.059
Worm
regulation of cell cycle phase transitionGO:1901987770.057
rna processingGO:00063961050.057
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.056
oligosaccharide catabolic processGO:000931320.053
genitalia developmentGO:0048806370.052
carbohydrate metabolic processGO:00059752300.052
methylationGO:00322591340.051
establishment of protein localization to organelleGO:00725941180.051
oocyte axis specificationGO:000730920.051
Fly
positive regulation of chromosome segregationGO:005198440.047
blastocyst developmentGO:0001824800.047
regulation of wnt signaling pathwayGO:00301111230.047
mitotic cell cycle processGO:19030471590.044
peptidyl lysine modificationGO:0018205770.044
muscle cell differentiationGO:00426922610.042
atp dependent chromatin remodelingGO:004304490.040
endocytosisGO:00068971680.040
nls bearing protein import into nucleusGO:000660720.040
multi multicellular organism processGO:00447061090.039
purine nucleotide catabolic processGO:00061952110.039
snrna 3 end processingGO:003447210.038
regulation of mitotic sister chromatid segregationGO:0033047120.037
receptor mediated endocytosisGO:0006898510.035
rna splicingGO:0008380540.035
Human
positive regulation of cell cycleGO:0045787920.035
g1 s transition of mitotic cell cycleGO:0000082570.032
chromatin modificationGO:00165681870.031
gonad developmentGO:00084061410.031
organism emergence from protective structureGO:007168440.030
meiosis iGO:0007127600.030
positive regulation of programmed cell deathGO:00430682180.029
atp catabolic processGO:0006200550.029
blastocyst hatchingGO:000183540.029
membrane organizationGO:00610242450.028
hatchingGO:003518840.028
regulation of protein catabolic processGO:00421761080.028
histone modificationGO:00165701590.028
viral transcriptionGO:001908330.027
regulation of proteasomal protein catabolic processGO:0061136460.027
mrna metabolic processGO:0016071840.027
Human
regulation of cell cycle g2 m phase transitionGO:1902749100.027
maintenance of locationGO:0051235890.026
male meiosisGO:0007140370.026
maturation of lsu rrnaGO:000047010.026
positive regulation of mitotic sister chromatid separationGO:190197020.025
metaphase plate congressionGO:005131020.025
chromatin remodeling at centromereGO:003105520.025
positive regulation of mitotic cell cycle phase transitionGO:1901992170.025
chromosome segregationGO:0007059480.024
regulation of organelle organizationGO:00330432890.024
cellular protein complex assemblyGO:00436231160.024
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.023
intracellular mrna localizationGO:000829840.023
Fly
biofilm formationGO:004271010.023
macromolecule catabolic processGO:00090572810.023
oocyte developmentGO:0048599330.023
Fly
stem cell differentiationGO:00488632680.022
regulation of cell motilityGO:20001452360.022
cellularizationGO:000734910.022
lipid localizationGO:00108761260.021
myeloid cell differentiationGO:00300992330.021
single species biofilm formationGO:004401010.021
organelle fissionGO:00482851700.021
homeostasis of number of cellsGO:00488722100.021
t cell proliferationGO:00420981200.021
viral gene expressionGO:001908030.021
megakaryocyte differentiationGO:0030219260.020
mitotic nuclear divisionGO:0007067480.020
cellular amino acid metabolic processGO:00065201030.020
ribonucleoside monophosphate metabolic processGO:0009161800.020
response to uvGO:0009411440.020
regulation of reproductive processGO:2000241660.020
proteasomal protein catabolic processGO:0010498980.020
mitochondrial calcium ion homeostasisGO:005156070.019
regulation of cell substrate adhesionGO:0010810730.019
maturation of 5 8s rrnaGO:000046010.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
positive regulation of cell cycle phase transitionGO:1901989170.019
regulation of cell cycle g1 s phase transitionGO:1902806350.019
oocyte constructionGO:000730820.019
Fly
cell cycle g1 s phase transitionGO:0044843570.019
muscle cell developmentGO:00550011330.018
cellular response to hormone stimulusGO:00328701500.018
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.018
microtubule cytoskeleton organizationGO:00002261570.018
cellular response to lipidGO:00713961450.018
Fly
response to extracellular stimulusGO:00099911270.018
female gamete generationGO:0007292740.017
Fly
protein localization to organelleGO:00333651850.017
snrna metabolic processGO:001607310.017
dna damage response signal transduction by p53 class mediatorGO:0030330190.017
Worm
negative regulation of cell cycleGO:00457861230.017
regulation of g1 s transition of mitotic cell cycleGO:2000045350.017
protein localization to chromosome centromeric regionGO:007145910.017
rrna transcriptionGO:000930390.016
microtubule cytoskeleton organization involved in mitosisGO:190285040.016
regulation of mitotic cell cycleGO:00073461260.016
purine nucleoside monophosphate catabolic processGO:0009128580.016
ncrna 3 end processingGO:004362820.016
response to peptide hormoneGO:00434341270.016
positive regulation of growthGO:00459271040.016
response to organonitrogen compoundGO:00102432460.015
cellular response to dna damage stimulusGO:00069742070.015
Worm
wnt signaling pathwayGO:00160551880.015
purine nucleoside monophosphate metabolic processGO:0009126810.015
positive regulation of dendritic cell chemotaxisGO:200051010.015
ubiquitin dependent protein catabolic processGO:00065111290.015
protein processingGO:00164851630.015
snorna metabolic processGO:001607410.015
regulation of transferase activityGO:00513382630.015
histone demethylationGO:0016577130.015
cellular protein catabolic processGO:00442571550.015
regulation of protein maturationGO:1903317960.015
mitochondrion organizationGO:00070051340.014
positive regulation of cell activationGO:00508671580.014
positive regulation of protein modification processGO:00314012990.014
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046310.014
purine nucleotide metabolic processGO:00061633020.014
positive regulation of cell substrate adhesionGO:0010811470.014
regulation of body fluid levelsGO:00508781620.014
aspartate family amino acid metabolic processGO:0009066100.014
positive regulation of cell cycle processGO:0090068610.014
regulation of androgen receptor signaling pathwayGO:006076530.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
response to organic cyclic compoundGO:00140701980.014
Fly
nucleoside phosphate catabolic processGO:19012922220.014
ribose phosphate metabolic processGO:00196932910.014
transcription from rna polymerase i promoterGO:0006360130.014
nucleic acid phosphodiester bond hydrolysisGO:0090305490.014
reactive nitrogen species metabolic processGO:200105700.013
negative regulation of cell cycle arrestGO:007115710.013
cardiac chamber morphogenesisGO:0003206930.013
transdifferentiationGO:006029010.013
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000047910.013
disaccharide metabolic processGO:000598410.013
negative regulation of reproductive processGO:2000242310.013
myosin filament assemblyGO:003103420.013
urogenital system developmentGO:00016552610.013
development of primary sexual characteristicsGO:00451371430.013
regulation of mrna metabolic processGO:1903311430.013
regulation of cell divisionGO:0051302760.013
cellular carbohydrate metabolic processGO:00442621190.012
cellular component assembly involved in morphogenesisGO:00109271390.012
nucleolus organizationGO:000700050.012
establishment of protein localization to membraneGO:0090150540.012
negative regulation of cell cycle phase transitionGO:1901988480.012
protein catabolic processGO:00301632210.012
histone lysine demethylationGO:0070076130.012
nucleoside phosphate metabolic processGO:00067533380.012
nucleoside monophosphate metabolic processGO:0009123850.012
morphogenesis of an endotheliumGO:000315920.012
midgut developmentGO:000749440.012
cellular nitrogen compound catabolic processGO:00442702800.012
cytoplasmic transportGO:00164822340.012
cellular response to radiationGO:0071478280.012
meiotic cell cycle processGO:1903046770.012
negative regulation of cell cycle processGO:0010948690.012
positive regulation of mrna processingGO:0050685160.012
positive regulation of b cell activationGO:0050871490.012
nucleotide catabolic processGO:00091662170.012
localization within membraneGO:005166840.012
tube closureGO:0060606910.012
spliceosomal complex disassemblyGO:000039010.012
actin cytoskeleton organizationGO:00300362200.012
cell divisionGO:00513011200.011
regulation of mitochondrial translationGO:007012930.011
modification dependent protein catabolic processGO:00199411330.011
response to light stimulusGO:00094161350.011
positive regulation of cellular protein catabolic processGO:1903364340.011
positive regulation of protein phosphorylationGO:00019342420.011
lymphocyte mediated immunityGO:00024491390.011
chromosome separationGO:0051304140.011
response to insulinGO:00328681000.011
glycosyl compound catabolic processGO:19016582060.011
modification dependent macromolecule catabolic processGO:00436321330.011
leukocyte proliferationGO:00706611720.011
skeletal system developmentGO:00015013560.011
purine ribonucleotide catabolic processGO:00091542080.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
positive regulation of immune effector processGO:00026991070.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
stem cell developmentGO:00488642190.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.011
gene silencingGO:0016458380.011
leukocyte differentiationGO:00025213420.010
nucleobase containing small molecule metabolic processGO:00550863520.010
positive regulation of apoptotic processGO:00430652170.010
striated muscle cell developmentGO:00550021250.010
regulation of cellular catabolic processGO:00313292420.010
cellular homeostasisGO:00197252400.010
response to inorganic substanceGO:0010035960.010
purine ribonucleotide metabolic processGO:00091502900.010
regulation of cell activationGO:00508652890.010
rig i signaling pathwayGO:003952940.010
positive regulation of cell adhesionGO:0045785800.010

Prmt5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye and adnexa diseaseDOID:149200.027
retinal diseaseDOID:567900.027
eye diseaseDOID:561400.027
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
sensory system diseaseDOID:005015500.027
retinal degenerationDOID:846600.021
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010
immune system cancerDOID:006008300.010
organ system cancerDOID:005068600.010
inherited metabolic disorderDOID:65500.010
disease of metabolismDOID:001466700.010