Mus musculus

95 known processes

Spink2

serine peptidase inhibitor, Kazal type 2

(Aliases: 1700007F22Rik,HUSI-II,MGC107139,AV038945)

Spink2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna methylation involved in gamete generationGO:0043046150.083
male gamete generationGO:00482322850.081
cation transportGO:00068123990.074
spermatogenesisGO:00072832840.067
ion transmembrane transportGO:00342203610.067
cellular amine metabolic processGO:0044106440.064
cation transmembrane transportGO:00986552660.057
transmembrane transportGO:00550854120.051
cellular amino acid metabolic processGO:00065201030.046
anion transportGO:00068201770.042
inorganic cation transmembrane transportGO:00986622070.040
cellular ketone metabolic processGO:0042180840.037
nucleotide metabolic processGO:00091173320.035
male meiosisGO:0007140370.035
muscle system processGO:00030121410.035
pirna metabolic processGO:0034587120.035
meiotic cell cycleGO:00513211220.035
cellular homeostasisGO:00197252400.035
spermatid developmentGO:00072861080.034
regulation of cellular amino acid metabolic processGO:000652150.034
regulation of cellular ketone metabolic processGO:0010565660.032
inflammatory responseGO:00069542440.032
glycerolipid metabolic processGO:00464861220.031
organelle fissionGO:00482851700.031
pole plasm assemblyGO:000731520.030
immune effector processGO:00022523210.030
regulation of organelle organizationGO:00330432890.030
circulatory system processGO:00030131970.029
nuclear divisionGO:00002801580.029
nucleoside phosphate metabolic processGO:00067533380.029
cellular lipid metabolic processGO:00442553230.029
meiotic nuclear divisionGO:00071261150.028
regulation of defense responseGO:00313472330.028
inorganic ion transmembrane transportGO:00986602340.028
cytokine productionGO:00018163190.028
regulation of cell cycleGO:00517262810.027
carbohydrate derivative biosynthetic processGO:19011371830.027
small gtpase mediated signal transductionGO:0007264970.027
macromolecule catabolic processGO:00090572810.027
organic cyclic compound catabolic processGO:19013612950.026
oxidation reduction processGO:00551143420.026
sperm motilityGO:0030317470.026
Mouse
regulation of ion transportGO:00432692150.026
regulation of cytokine productionGO:00018172660.026
organonitrogen compound biosynthetic processGO:19015661920.026
purine nucleotide metabolic processGO:00061633020.025
nitrogen compound transportGO:00717052710.025
oocyte axis specificationGO:000730920.025
rna interferenceGO:001624620.025
methylationGO:00322591340.024
mitotic cell cycleGO:00002781950.024
regulation of cellular catabolic processGO:00313292420.024
amine metabolic processGO:0009308450.024
chromatin organizationGO:00063252060.023
nucleobase containing small molecule metabolic processGO:00550863520.023
purine containing compound metabolic processGO:00725213110.023
striated muscle tissue developmentGO:00147062930.023
heterocycle catabolic processGO:00467002800.023
glycosyl compound metabolic processGO:19016572460.022
cellular ion homeostasisGO:00068731650.022
response to molecule of bacterial originGO:00022371430.022
divalent metal ion transportGO:00708381720.022
sodium ion transportGO:0006814730.022
ribose phosphate metabolic processGO:00196932910.022
fertilizationGO:00095661270.022
regulation of membrane potentialGO:00423911920.022
positive regulation of cytokine productionGO:00018191740.021
peptidyl amino acid modificationGO:00181933360.021
sulfur compound metabolic processGO:00067901000.021
carbohydrate metabolic processGO:00059752300.021
cellular chemical homeostasisGO:00550822150.021
meiosis iGO:0007127600.021
negative regulation of intracellular signal transductionGO:19025321670.021
regulation of secretion by cellGO:19035302490.021
negative regulation of protein metabolic processGO:00512482820.021
oocyte constructionGO:000730820.021
regulation of cellular amine metabolic processGO:0033238200.021
ribonucleoside metabolic processGO:00091192450.021
organic acid transportGO:00158491010.021
germ cell developmentGO:00072811850.020
negative regulation of cell proliferationGO:00082852960.020
spermatid differentiationGO:00485151150.020
protein catabolic processGO:00301632210.020
posttranscriptional regulation of gene expressionGO:00106081550.020
reactive oxygen species metabolic processGO:0072593840.020
dna metabolic processGO:00062593030.019
carboxylic acid transportGO:00469421000.019
nucleoside metabolic processGO:00091162460.019
fat cell differentiationGO:00454441600.019
multicellular organismal homeostasisGO:00488711640.019
homeostasis of number of cellsGO:00488722100.019
membrane organizationGO:00610242450.019
ribonucleotide metabolic processGO:00092592910.019
mitotic cell cycle processGO:19030471590.019
macromolecule methylationGO:00434141200.019
cellular response to lipidGO:00713961450.019
organophosphate biosynthetic processGO:00904071220.018
regulation of response to woundingGO:19030341890.018
myeloid cell differentiationGO:00300992330.018
tissue homeostasisGO:00018941150.018
purine nucleoside metabolic processGO:00422782410.018
positive regulation of defense responseGO:00313491240.018
regulation of cell cycle processGO:00105641600.018
regulation of cell activationGO:00508652890.018
regulation of transmembrane transportGO:00347621280.018
ras protein signal transductionGO:0007265770.018
organic anion transportGO:00157111370.018
regulation of protein localizationGO:00328802310.018
anatomical structure homeostasisGO:00602491450.017
intracellular mrna localizationGO:000829840.017
divalent inorganic cation transportGO:00725111780.017
protein localization to organelleGO:00333651850.017
cellular nitrogen compound catabolic processGO:00442702800.017
muscle contractionGO:00069361010.017
locomotory behaviorGO:00076261950.017
covalent chromatin modificationGO:00165691630.017
leukocyte differentiationGO:00025213420.017
synapsisGO:0007129340.017
positive regulation of nervous system developmentGO:00519622210.017
forebrain developmentGO:00309003020.017
negative regulation of cellular component organizationGO:00511291940.016
amino acid transportGO:0006865610.016
regulation of cellular component biogenesisGO:00440871810.016
response to lipopolysaccharideGO:00324961280.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
organonitrogen compound catabolic processGO:19015652640.016
regulation of muscle system processGO:0090257800.016
multi multicellular organism processGO:00447061090.016
cation homeostasisGO:00550802120.016
response to light stimulusGO:00094161350.016
meiotic cell cycle processGO:1903046770.016
regulation of multi organism processGO:00439001110.016
Mouse
carbohydrate derivative catabolic processGO:19011362310.016
nucleoside triphosphate metabolic processGO:00091412300.016
purine ribonucleotide metabolic processGO:00091502900.016
sequestering of metal ionGO:0051238190.016
positive regulation of cellular amine metabolic processGO:003324050.016
maternal determination of anterior posterior axis embryoGO:000835820.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
intracellular protein transportGO:00068862040.016
purine ribonucleoside metabolic processGO:00461282410.016
positive regulation of organelle organizationGO:00106381280.015
cellular calcium ion homeostasisGO:00068741190.015
oocyte anterior posterior axis specificationGO:000731420.015
aromatic compound catabolic processGO:00194392860.015
calcium ion homeostasisGO:00550741270.015
metal ion homeostasisGO:00550651890.015
regulation of anatomical structure sizeGO:00900661780.015
regulation of hormone levelsGO:00108172110.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
positive regulation of cell deathGO:00109422240.015
maintenance of locationGO:0051235890.015
protein maturationGO:00516041760.015
gonad developmentGO:00084061410.015
regulation of secretionGO:00510462740.015
cellular protein complex assemblyGO:00436231160.015
nucleoside triphosphate catabolic processGO:00091432050.015
muscle tissue developmentGO:00605373080.015
sensory perceptionGO:00076002450.015
protein modification by small protein conjugationGO:00324461870.015
lipid biosynthetic processGO:00086101790.015
skeletal system developmentGO:00015013560.015
ossificationGO:00015032160.015
organic hydroxy compound transportGO:0015850930.015
negative regulation of cellular protein metabolic processGO:00322692470.015
ribonucleoside monophosphate metabolic processGO:0009161800.014
blood circulationGO:00080151950.014
action potentialGO:0001508780.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
innate immune responseGO:00450871570.014
apoptotic signaling pathwayGO:00971903060.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
purine nucleotide catabolic processGO:00061952110.014
glycoprotein biosynthetic processGO:0009101890.014
regulation of intracellular transportGO:00323861590.014
skeletal muscle organ developmentGO:00605381630.014
regulation of system processGO:00440572000.014
cellular protein catabolic processGO:00442571550.014
exocytosisGO:00068871210.014
t cell activationGO:00421102890.014
dephosphorylationGO:00163111290.014
response to organonitrogen compoundGO:00102432460.014
cellular metal ion homeostasisGO:00068751510.014
histone modificationGO:00165701590.014
regionalizationGO:00030023370.014
rho protein signal transductionGO:0007266320.014
protein modification by small protein conjugation or removalGO:00706472070.013
regulation of nucleotide metabolic processGO:00061401690.013
g protein coupled receptor signaling pathwayGO:00071862430.013
negative regulation of immune system processGO:00026832090.013
ribonucleotide catabolic processGO:00092612080.013
glycerophospholipid metabolic processGO:0006650710.013
stem cell developmentGO:00488642190.013
endomembrane system organizationGO:00102561470.013
cell divisionGO:00513011200.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
chromatin modificationGO:00165681870.013
synaptic transmissionGO:00072683290.013
nucleoside monophosphate metabolic processGO:0009123850.013
protein ubiquitinationGO:00165671710.013
protein processingGO:00164851630.013
chromosome organization involved in meiosisGO:0070192390.013
multicellular organism growthGO:00352641610.013
kidney developmentGO:00018222130.013
atp metabolic processGO:0046034750.013
regulation of inflammatory responseGO:00507271470.013
nuclear transportGO:00511691390.013
negative regulation of transpositionGO:001052920.013
small molecule biosynthetic processGO:00442831320.013
organophosphate catabolic processGO:00464342320.013
regulation of transpositionGO:001052820.013
organic hydroxy compound metabolic processGO:19016152030.013
mapk cascadeGO:00001652810.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
asymmetric stem cell divisionGO:009872230.013
stem cell differentiationGO:00488632680.013
positive regulation of ion transportGO:0043270650.013
regulation of ion transmembrane transportGO:00347651190.013
cellular response to cytokine stimulusGO:00713451890.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.012
developmental maturationGO:00217001930.012
Mouse
regulation of vesicle mediated transportGO:00606271390.012
negative regulation of molecular functionGO:00440922580.012
response to inorganic substanceGO:0010035960.012
glycoprotein metabolic processGO:00091001160.012
rhythmic processGO:00485111740.012
purine nucleoside catabolic processGO:00061522050.012
microtubule based processGO:00070172360.012
negative regulation of cellular amine metabolic processGO:003323910.012
negative regulation of phosphate metabolic processGO:00459361840.012
protein localization to nucleusGO:00345041210.012
protein localization to membraneGO:00726571080.012
divalent inorganic cation homeostasisGO:00725071380.012
reactive nitrogen species metabolic processGO:200105700.012
regulation of transporter activityGO:0032409570.012
glycerolipid biosynthetic processGO:0045017500.012
purine containing compound catabolic processGO:00725232130.012
chromosome segregationGO:0007059480.012
regulation of translationGO:0006417710.012
positive regulation of cellular catabolic processGO:00313311480.012
dna recombinationGO:0006310920.012
regulation of homeostatic processGO:00328441820.012
myeloid leukocyte differentiationGO:00025731190.012
regulation of blood pressureGO:0008217930.012
nucleocytoplasmic transportGO:00069131390.012
regulation of lymphocyte activationGO:00512492400.012
leukocyte mediated immunityGO:00024431740.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
regulation of neuron differentiationGO:00456642810.012
negative regulation of cell cycleGO:00457861230.012
nucleoside catabolic processGO:00091642060.012
regulation of establishment of protein localizationGO:00702011810.012
blood vessel morphogenesisGO:00485142850.012
development of primary sexual characteristicsGO:00451371430.012
response to organic cyclic compoundGO:00140701980.012
negative regulation of cellular amino acid metabolic processGO:004576300.011
hexose metabolic processGO:0019318980.011
mitotic chromosome condensationGO:000707610.011
regulation of cytoplasmic transportGO:19036491120.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
negative regulation of phosphorus metabolic processGO:00105631840.011
cell activation involved in immune responseGO:00022631260.011
cytokine metabolic processGO:0042107710.011
embryonic organ morphogenesisGO:00485622760.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
regulation of purine nucleotide metabolic processGO:19005421690.011
engulfment of apoptotic cellGO:004365230.011
positive regulation of protein modification processGO:00314012990.011
cytoplasmic transportGO:00164822340.011
adult behaviorGO:00305341350.011
alcohol metabolic processGO:00060661160.011
positive regulation of cell developmentGO:00107202370.011
response to radiationGO:00093141650.011
regulation of ion transmembrane transporter activityGO:0032412540.011
epithelial cell developmentGO:00020641590.011
gene silencingGO:0016458380.011
positive regulation of innate immune responseGO:0045089800.011
defense response to bacteriumGO:00427421190.011
heart contractionGO:0060047930.011
chemotaxisGO:00069352470.011
gland developmentGO:00487323300.011
cellularizationGO:000734910.011
negative regulation of organelle organizationGO:0010639900.011
renal system developmentGO:00720012250.011
lipid transportGO:0006869980.011
regulation of mitotic cell cycleGO:00073461260.011
striated muscle contractionGO:0006941450.011
regulation of apoptotic signaling pathwayGO:20012331970.011
lymphocyte proliferationGO:00466511640.011
monocarboxylic acid metabolic processGO:00327871910.011
protein targetingGO:00066051430.010
proteolysis involved in cellular protein catabolic processGO:00516031470.010
glucose homeostasisGO:00425931280.010
cellular response to organonitrogen compoundGO:00714171450.010
leukocyte mediated cytotoxicityGO:0001909620.010
regulation of feeding behaviorGO:006025930.010
cellular carbohydrate metabolic processGO:00442621190.010
regulation of blood circulationGO:1903522930.010
phospholipid metabolic processGO:0006644870.010
regulation of cell motilityGO:20001452360.010
Mouse
regulation of tube sizeGO:0035150570.010
generation of precursor metabolites and energyGO:00060911030.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.010
cellular response to growth factor stimulusGO:00713631970.010
regulation of metal ion transportGO:00109591060.010
regulation of circadian sleep wake cycleGO:004274930.010
regulation of blood vessel sizeGO:0050880560.010
carbohydrate homeostasisGO:00335001280.010
nuclear importGO:0051170950.010
regulation of protein catabolic processGO:00421761080.010
nucleoside phosphate catabolic processGO:19012922220.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
axonogenesisGO:00074092740.010
regulation of hydrolase activityGO:00513362460.010

Spink2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
disease of cellular proliferationDOID:1456600.012
bone diseaseDOID:008000100.012
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012
disease of metabolismDOID:001466700.012