Mus musculus

66 known processes

Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

(Aliases: Pak5,6430627N20,2900083L08Rik,MGC117585)

Pak7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled glutamate receptor signaling pathwayGO:000721630.085
regulation of membrane potentialGO:00423911920.082
regulation of neuron differentiationGO:00456642810.067
Fly
synapse organizationGO:00508081250.067
cellular amine metabolic processGO:0044106440.064
synaptic transmissionGO:00072683290.062
retina development in camera type eyeGO:00600411190.061
locomotory behaviorGO:00076261950.059
cell adhesionGO:00071553290.055
Fly
purine nucleotide metabolic processGO:00061633020.053
regulation of secretion by cellGO:19035302490.051
ribonucleotide metabolic processGO:00092592910.049
metal ion homeostasisGO:00550651890.049
regulation of cellular ketone metabolic processGO:0010565660.046
regulation of secretionGO:00510462740.046
central nervous system neuron differentiationGO:00219531620.044
nucleotide metabolic processGO:00091173320.042
cation homeostasisGO:00550802120.041
inorganic cation transmembrane transportGO:00986622070.040
regulation of cellular amino acid metabolic processGO:000652150.039
purine ribonucleotide metabolic processGO:00091502900.037
positive regulation of nervous system developmentGO:00519622210.036
Fly
endocytosisGO:00068971680.036
dendrite developmentGO:00163581150.036
negative regulation of cellular component organizationGO:00511291940.036
amine metabolic processGO:0009308450.035
ion transmembrane transportGO:00342203610.035
nucleobase containing small molecule metabolic processGO:00550863520.035
purine containing compound metabolic processGO:00725213110.034
multicellular organismal signalingGO:0035637910.034
regulation of cellular amine metabolic processGO:0033238200.034
regulation of protein kinase activityGO:00458592320.033
regulation of cellular component biogenesisGO:00440871810.033
nucleoside phosphate metabolic processGO:00067533380.033
heterocycle catabolic processGO:00467002800.033
organelle localizationGO:00516401790.033
positive regulation of protein modification processGO:00314012990.032
regulation of protein serine threonine kinase activityGO:00719001570.032
forebrain developmentGO:00309003020.031
transmission of nerve impulseGO:0019226760.031
establishment of organelle localizationGO:00516561220.031
positive regulation of cell developmentGO:00107202370.031
Fly
regulation of vesicle mediated transportGO:00606271390.031
purine ribonucleotide catabolic processGO:00091542080.031
cellular amino acid metabolic processGO:00065201030.030
membrane organizationGO:00610242450.030
cellular homeostasisGO:00197252400.029
single organism cell adhesionGO:00986021560.029
Fly
regulation of map kinase activityGO:00434051200.029
synaptic transmission glutamatergicGO:0035249360.028
regulation of neuron projection developmentGO:00109751690.028
rap protein signal transductionGO:003248630.028
endomembrane system organizationGO:00102561470.027
Fly
regulation of cell projection organizationGO:00313442060.027
exocytosisGO:00068871210.027
inorganic ion transmembrane transportGO:00986602340.027
camera type eye developmentGO:00430102660.027
neural precursor cell proliferationGO:00613511210.026
transmembrane transportGO:00550854120.026
axonogenesisGO:00074092740.026
positive regulation of protein phosphorylationGO:00019342420.026
regulation of transferase activityGO:00513382630.026
negative regulation of cell developmentGO:00107211690.026
regulation of organelle organizationGO:00330432890.026
calcium ion homeostasisGO:00550741270.025
actin cytoskeleton organizationGO:00300362200.025
cation transmembrane transportGO:00986552660.025
protein localization to membraneGO:00726571080.025
action potentialGO:0001508780.024
negative regulation of bone trabecula formationGO:190015510.024
small gtpase mediated signal transductionGO:0007264970.024
positive regulation of map kinase activityGO:0043406840.024
regulation of ion transportGO:00432692150.024
anion transportGO:00068201770.024
regulation of transmembrane transportGO:00347621280.024
regulation of mapk cascadeGO:00434082480.023
nucleoside metabolic processGO:00091162460.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
positive regulation of transferase activityGO:00513471670.023
regulation of exocytosisGO:0017157610.023
negative regulation of phosphorus metabolic processGO:00105631840.023
myeloid cell homeostasisGO:00022621140.023
regulation of cell adhesionGO:00301551540.023
Fly
synapse assemblyGO:0007416560.023
positive regulation of protein kinase activityGO:00458601440.022
purine nucleotide catabolic processGO:00061952110.022
mapk cascadeGO:00001652810.022
skeletal system developmentGO:00015013560.022
protein secretionGO:00093061110.022
immune effector processGO:00022523210.022
calcium ion transmembrane transportGO:0070588850.022
regulation of hydrolase activityGO:00513362460.022
cellular ketone metabolic processGO:0042180840.022
ras protein signal transductionGO:0007265770.021
homeostasis of number of cellsGO:00488722100.021
negative regulation of protein metabolic processGO:00512482820.021
learning or memoryGO:00076111480.021
regulation of synaptic plasticityGO:0048167870.021
negative regulation of phosphate metabolic processGO:00459361840.021
positive regulation of long term neuronal synaptic plasticityGO:004817030.021
cellularizationGO:000734910.021
peptide hormone secretionGO:00300721090.021
activation of mapk activityGO:0000187590.021
regulation of excitatory postsynaptic membrane potentialGO:0060079410.021
negative regulation of cellular amine metabolic processGO:003323910.021
nitrogen compound transportGO:00717052710.021
regulation of cell motilityGO:20001452360.021
negative regulation of cellular amino acid metabolic processGO:004576300.021
ribose phosphate metabolic processGO:00196932910.020
notochord cell developmentGO:006003510.020
positive regulation of mapk cascadeGO:00434101700.020
establishment of vesicle localizationGO:0051650810.020
gtp metabolic processGO:00460391440.020
regulation of cellular catabolic processGO:00313292420.020
cognitionGO:00508901490.020
ribonucleoside metabolic processGO:00091192450.020
apoptotic signaling pathwayGO:00971903060.020
aromatic compound catabolic processGO:00194392860.020
adult behaviorGO:00305341350.020
immune response regulating signaling pathwayGO:00027641250.020
nucleoside phosphate catabolic processGO:19012922220.020
nucleoside catabolic processGO:00091642060.020
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711330.019
positive regulation of protein serine threonine kinase activityGO:00719021060.019
negative regulation of phosphorylationGO:00423261660.019
ribonucleoside catabolic processGO:00424542060.019
multicellular organism growthGO:00352641610.019
divalent inorganic cation homeostasisGO:00725071380.019
microtubule based processGO:00070172360.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
regulation of long term neuronal synaptic plasticityGO:0048169190.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
morphogenesis of a branching structureGO:00017632030.019
negative regulation of immune system processGO:00026832090.019
stem cell differentiationGO:00488632680.019
divalent metal ion transportGO:00708381720.019
regulation of nucleotide metabolic processGO:00061401690.018
chemotaxisGO:00069352470.018
cellular nitrogen compound catabolic processGO:00442702800.018
neural tube developmentGO:00219151600.018
dephosphorylationGO:00163111290.018
purine nucleoside catabolic processGO:00061522050.018
regulation of protein transportGO:00512231630.018
purine nucleoside metabolic processGO:00422782410.018
nucleotide catabolic processGO:00091662170.018
glycosyl compound catabolic processGO:19016582060.018
ribonucleotide catabolic processGO:00092612080.018
regulation of leukocyte differentiationGO:19021051590.017
regulation of cell migrationGO:00303342190.017
negative regulation of protein modification processGO:00314001630.017
cellular chemical homeostasisGO:00550822150.017
regulation of feeding behaviorGO:006025930.017
maternal determination of anterior posterior axis embryoGO:000835820.017
negative regulation of molecular functionGO:00440922580.017
regulation of neuron deathGO:19012141340.017
cell growthGO:00160491300.017
regulation of purine nucleotide metabolic processGO:19005421690.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
regulation of multi organism processGO:00439001110.017
fatty acid metabolic processGO:00066311210.017
t cell activationGO:00421102890.017
adult locomotory behaviorGO:0008344910.017
nucleoside triphosphate metabolic processGO:00091412300.016
regulation of cytokine productionGO:00018172660.016
neuron projection guidanceGO:00974851410.016
divalent inorganic cation transportGO:00725111780.016
central nervous system neuron developmentGO:0021954670.016
glycosyl compound metabolic processGO:19016572460.016
neuron migrationGO:00017641220.016
cellular response to lipidGO:00713961450.016
regulation of kinase activityGO:00435492490.016
neurotransmitter transportGO:0006836760.016
neuronal action potentialGO:0019228540.016
purine ribonucleoside metabolic processGO:00461282410.016
regulation of glutamate receptor signaling pathwayGO:1900449160.016
cell type specific apoptotic processGO:00972852680.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
synaptic vesicle localizationGO:0097479590.016
membrane depolarizationGO:0051899640.015
axon ensheathmentGO:0008366760.015
telencephalon developmentGO:00215371860.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
organophosphate catabolic processGO:00464342320.015
negative regulation of intracellular signal transductionGO:19025321670.015
cytokine productionGO:00018163190.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
neuromuscular processGO:0050905990.015
adult walking behaviorGO:0007628410.015
positive regulation of programmed cell deathGO:00430682180.015
posttranscriptional regulation of gene expressionGO:00106081550.015
engulfment of apoptotic cellGO:004365230.015
positive regulation of kinase activityGO:00336741550.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
purine ribonucleoside catabolic processGO:00461302050.015
plasma membrane organizationGO:0007009900.015
protein modification by small protein conjugation or removalGO:00706472070.015
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.015
retina morphogenesis in camera type eyeGO:0060042450.015
anatomical structure homeostasisGO:00602491450.015
detection of external stimulusGO:0009581610.015
positive regulation of secretionGO:00510471300.015
memoryGO:0007613580.014
glucose homeostasisGO:00425931280.014
regulation of proteolysisGO:00301621640.014
regulation of myeloid cell differentiationGO:0045637960.014
glutamate receptor signaling pathwayGO:0007215350.014
cellular lipid metabolic processGO:00442553230.014
guanosine containing compound catabolic processGO:19010691440.014
feeding behaviorGO:0007631620.014
amino acid transportGO:0006865610.014
protein maturationGO:00516041760.014
photoreceptor cell differentiationGO:0046530520.014
Fly
negative regulation of cellular protein metabolic processGO:00322692470.014
sensory perception of light stimulusGO:0050953540.014
purine containing compound catabolic processGO:00725232130.014
epithelial tube morphogenesisGO:00605623030.014
glial cell differentiationGO:00100011310.014
protein ubiquitinationGO:00165671710.014
response to organonitrogen compoundGO:00102432460.014
protein localization to synapseGO:0035418110.014
cellular metal ion homeostasisGO:00068751510.014
cell fate commitmentGO:00451652100.014
Fly
response to lipopolysaccharideGO:00324961280.014
organic hydroxy compound metabolic processGO:19016152030.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
neuron neuron synaptic transmissionGO:0007270690.014
regulation of purine nucleotide catabolic processGO:00331211220.014
leukocyte differentiationGO:00025213420.014
embryonic organ morphogenesisGO:00485622760.014
peptide secretionGO:00027901140.013
inter male aggressive behaviorGO:000212130.013
protein localization to juxtaparanode region of axonGO:007120540.013
regulation of cellular component sizeGO:00325351210.013
Fly
regulation of neuronal synaptic plasticityGO:0048168300.013
central nervous system projection neuron axonogenesisGO:0021952210.013
peptidyl amino acid modificationGO:00181933360.013
Fly
learningGO:0007612980.013
muscle tissue developmentGO:00605373080.013
defecationGO:003042110.013
regulation of response to woundingGO:19030341890.013
lateral line system developmentGO:004892510.013
carbohydrate derivative catabolic processGO:19011362310.013
lateral inhibitionGO:004633110.013
Fly
negative regulation of organelle organizationGO:0010639900.013
vesicle localizationGO:0051648860.013
positive regulation of neuron differentiationGO:00456661410.013
Fly
carbohydrate derivative biosynthetic processGO:19011371830.013
cell substrate adhesionGO:00315891300.013
gland developmentGO:00487323300.013
cell activation involved in immune responseGO:00022631260.013
protein modification by small protein conjugationGO:00324461870.013
insulin secretionGO:0030073890.013
regulation of establishment of protein localizationGO:00702011810.013
morphogenesis of embryonic epitheliumGO:00163311590.013
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
protein catabolic processGO:00301632210.012
organic anion transportGO:00157111370.012
regulation of cytoskeleton organizationGO:00514931220.012
regulation of protein localizationGO:00328802310.012
intracellular protein transportGO:00068862040.012
lymphocyte differentiationGO:00300982420.012
spermatogenesisGO:00072832840.012
rna processingGO:00063961050.012
regulation of cell sizeGO:0008361720.012
Fly
stem cell developmentGO:00488642190.012
regulation of ion transmembrane transportGO:00347651190.012
rho protein signal transductionGO:0007266320.012
sensory organ morphogenesisGO:00905962420.012
Fly
neural tube closureGO:0001843900.012
sensory perception of painGO:0019233470.012
oocyte constructionGO:000730820.012
central nervous system neuron axonogenesisGO:0021955280.012
myeloid cell differentiationGO:00300992330.012
dorsal ventral axon guidanceGO:003356330.012
negative regulation of cell proliferationGO:00082852960.012
erythrocyte differentiationGO:0030218880.012
cell recognitionGO:0008037830.012
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.012
myeloid leukocyte differentiationGO:00025731190.012
regulation of system processGO:00440572000.012
organonitrogen compound catabolic processGO:19015652640.012
organic cyclic compound catabolic processGO:19013612950.012
regulation of glial cell differentiationGO:0045685410.012
immune response activating signal transductionGO:00027571160.012
axoneme assemblyGO:0035082150.012
hematopoietic progenitor cell differentiationGO:00022441430.012
detection of stimulus involved in sensory perceptionGO:0050906440.012
cation transportGO:00068123990.011
negative regulation of secretion by cellGO:1903531540.011
compound eye developmentGO:004874910.011
Fly
positive regulation of secretion by cellGO:19035321140.011
regulation of protein catabolic processGO:00421761080.011
organonitrogen compound biosynthetic processGO:19015661920.011
regulation of homeostatic processGO:00328441820.011
oxidation reduction processGO:00551143420.011
regulation of neurotransmitter levelsGO:0001505870.011
guanosine containing compound metabolic processGO:19010681440.011
protein processingGO:00164851630.011
axon guidanceGO:00074111410.011
eye photoreceptor cell differentiationGO:0001754410.011
Fly
carboxylic acid transportGO:00469421000.011
multicellular organismal homeostasisGO:00488711640.011
skin developmentGO:00435882200.011
synaptic vesicle transportGO:0048489570.011
neuromuscular process controlling balanceGO:0050885590.011
reactive oxygen species metabolic processGO:0072593840.011
negative regulation of protein phosphorylationGO:00019331260.011
negative regulation of neuron projection regenerationGO:007057130.011
cellular ion homeostasisGO:00068731650.011
gliogenesisGO:00420631410.011
neural retina developmentGO:0003407410.011
ensheathment of neuronsGO:0007272760.011
striated muscle tissue developmentGO:00147062930.011
sensory perceptionGO:00076002450.011
organophosphate biosynthetic processGO:00904071220.011
maintenance of locationGO:0051235890.011
single organismal cell cell adhesionGO:00163371310.011
Fly
organelle fissionGO:00482851700.011
peptidyl tyrosine phosphorylationGO:00181081430.011
eye photoreceptor cell developmentGO:0042462310.011
Fly
photoreceptor cell maintenanceGO:0045494190.011
calcium ion transportGO:00068161590.011
response to molecule of bacterial originGO:00022371430.011
fat cell differentiationGO:00454441600.011
positive regulation of cellular amine metabolic processGO:003324050.010
cellular response to abiotic stimulusGO:0071214560.010
regulation of body fluid levelsGO:00508781620.010
regionalizationGO:00030023370.010
regulation of nucleoside metabolic processGO:00091181300.010
negative regulation of nervous system developmentGO:00519611560.010
regulation of gliogenesisGO:0014013500.010
regulation of actin cytoskeleton organizationGO:0032956840.010
developmental maturationGO:00217001930.010
amide transportGO:00428861380.010
terminal button organizationGO:007255330.010
cell maturationGO:00484691270.010
regulation of cellular response to stressGO:00801351590.010
leukocyte mediated immunityGO:00024431740.010
norepinephrine transportGO:001587420.010
organic acid transportGO:00158491010.010
regulation of postsynaptic membrane potentialGO:0060078480.010
peptide transportGO:00158331330.010
positive regulation of organelle organizationGO:00106381280.010

Pak7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.049
nervous system diseaseDOID:86300.049
disease of anatomical entityDOID:700.049
eye and adnexa diseaseDOID:149200.049
eye diseaseDOID:561400.031
organ system cancerDOID:005068600.025
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025
retinal degenerationDOID:846600.024
retinal diseaseDOID:567900.024