Mus musculus

11 known processes

Rttn

rotatin

(Aliases: 4921538A15Rik,AI666264,D230040K24,C530033I08Rik)

Rttn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.790
dna recombinationGO:0006310920.743
dna repairGO:00062811070.734
cellular response to dna damage stimulusGO:00069742070.718
double strand break repairGO:0006302480.691
recombinational repairGO:0000725210.387
double strand break repair via homologous recombinationGO:0000724210.285
aromatic compound catabolic processGO:00194392860.261
organic cyclic compound catabolic processGO:19013612950.233
response to radiationGO:00093141650.228
purine nucleoside catabolic processGO:00061522050.195
leukocyte differentiationGO:00025213420.186
purine ribonucleotide catabolic processGO:00091542080.184
purine containing compound catabolic processGO:00725232130.181
heterocycle catabolic processGO:00467002800.174
nucleoside triphosphate catabolic processGO:00091432050.170
cellular nitrogen compound catabolic processGO:00442702800.161
carbohydrate derivative catabolic processGO:19011362310.147
meiotic cell cycle processGO:1903046770.147
nucleoside triphosphate metabolic processGO:00091412300.143
nucleoside phosphate catabolic processGO:19012922220.137
dna dependent dna replication maintenance of fidelityGO:004500530.131
purine nucleotide catabolic processGO:00061952110.129
meiosis iGO:0007127600.123
nucleoside metabolic processGO:00091162460.123
purine containing compound metabolic processGO:00725213110.122
nucleobase containing small molecule metabolic processGO:00550863520.117
glycosyl compound metabolic processGO:19016572460.115
telomere maintenanceGO:0000723190.112
multicellular organism growthGO:00352641610.111
organophosphate catabolic processGO:00464342320.108
purine nucleotide metabolic processGO:00061633020.107
ribonucleotide catabolic processGO:00092612080.106
glycosyl compound catabolic processGO:19016582060.103
purine ribonucleoside triphosphate metabolic processGO:00092052200.103
mitotic cell cycleGO:00002781950.099
lymphocyte differentiationGO:00300982420.098
dna biosynthetic processGO:0071897220.096
purine nucleoside triphosphate catabolic processGO:00091462030.095
meiotic cell cycleGO:00513211220.093
organonitrogen compound catabolic processGO:19015652640.092
regulation of mitotic cell cycle phase transitionGO:1901990730.092
regulation of hydrolase activityGO:00513362460.092
cellular amino acid metabolic processGO:00065201030.089
ribonucleotide metabolic processGO:00092592910.088
positive regulation of cellular amino acid metabolic processGO:004576430.084
purine ribonucleotide metabolic processGO:00091502900.083
regulation of cell activationGO:00508652890.078
b cell activationGO:00421131610.077
meiotic nuclear divisionGO:00071261150.076
regulation of cell cycle processGO:00105641600.076
regulation of lymphocyte activationGO:00512492400.075
nuclear divisionGO:00002801580.074
nucleoside phosphate metabolic processGO:00067533380.073
regulation of cellular amino acid metabolic processGO:000652150.073
ribonucleoside monophosphate metabolic processGO:0009161800.072
nucleoside catabolic processGO:00091642060.072
organelle fissionGO:00482851700.066
regulation of cell cycle phase transitionGO:1901987770.064
purine ribonucleoside triphosphate catabolic processGO:00092071990.063
atp catabolic processGO:0006200550.062
regulation of cell cycleGO:00517262810.061
purine nucleoside monophosphate catabolic processGO:0009128580.061
mitotic cell cycle processGO:19030471590.061
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.058
positive regulation of cellular amine metabolic processGO:003324050.057
ribose phosphate metabolic processGO:00196932910.057
purine nucleoside triphosphate metabolic processGO:00091442260.056
nucleotide metabolic processGO:00091173320.055
positive regulation of eosinophil migrationGO:200041820.054
regulation of cellular amine metabolic processGO:0033238200.054
regulation of leukocyte differentiationGO:19021051590.054
homeostasis of number of cellsGO:00488722100.054
purine nucleoside metabolic processGO:00422782410.054
nucleic acid phosphodiester bond hydrolysisGO:0090305490.053
purine nucleoside monophosphate metabolic processGO:0009126810.053
nucleotide catabolic processGO:00091662170.052
b cell differentiationGO:0030183780.050
cellular macromolecule catabolic processGO:00442652060.050
ras protein signal transductionGO:0007265770.047
blood vessel morphogenesisGO:00485142850.047
ribonucleoside triphosphate catabolic processGO:00092031990.046
purine ribonucleoside metabolic processGO:00461282410.046
t cell apoptotic processGO:0070231390.046
ribonucleoside catabolic processGO:00424542060.046
nucleoside monophosphate metabolic processGO:0009123850.045
rho protein signal transductionGO:0007266320.045
positive regulation of apoptotic processGO:00430652170.044
somatic diversification of immune receptorsGO:0002200530.044
cellular ketone metabolic processGO:0042180840.043
t cell differentiationGO:00302171740.043
cellular amine metabolic processGO:0044106440.042
purine ribonucleoside catabolic processGO:00461302050.042
neuronal action potentialGO:0019228540.042
regulation of cellular catabolic processGO:00313292420.041
positive regulation of hydrolase activityGO:00513451480.041
ribonucleoside monophosphate catabolic processGO:0009158570.041
nucleoside monophosphate catabolic processGO:0009125590.041
production of molecular mediator of immune responseGO:00024401030.041
regulation of cell divisionGO:0051302760.040
ribonucleoside triphosphate metabolic processGO:00091992200.040
response to light stimulusGO:00094161350.040
negative regulation of protein metabolic processGO:00512482820.039
mitotic recombinationGO:000631230.039
response to ionizing radiationGO:0010212420.039
purine ribonucleoside monophosphate metabolic processGO:0009167800.039
regulation of membrane potentialGO:00423911920.039
cell activation involved in immune responseGO:00022631260.038
leukocyte migrationGO:00509001240.038
cytokine productionGO:00018163190.036
activation of mapk activity involved in innate immune responseGO:003541920.036
chromatin organizationGO:00063252060.036
tumor necrosis factor ligand superfamily member 11 productionGO:007253510.035
somatic cell dna recombinationGO:0016444510.035
positive regulation of protein modification processGO:00314012990.035
dna replicationGO:0006260520.034
male meiosisGO:0007140370.034
small gtpase mediated signal transductionGO:0007264970.034
leukocyte apoptotic processGO:0071887710.034
atp metabolic processGO:0046034750.034
microtubule cytoskeleton organizationGO:00002261570.033
regulation of eosinophil migrationGO:200041620.033
protein maturationGO:00516041760.033
negative regulation of cellular component organizationGO:00511291940.033
nucleotide excision repairGO:0006289130.032
negative regulation of mitotic cell cycle phase transitionGO:1901991450.032
transmission of nerve impulseGO:0019226760.032
epithelial tube formationGO:00721751300.032
ribonucleoside metabolic processGO:00091192450.031
regulation of lymphocyte apoptotic processGO:0070228410.031
regulation of organelle organizationGO:00330432890.031
chromatin modificationGO:00165681870.031
macromolecule catabolic processGO:00090572810.031
immunoglobulin productionGO:0002377730.030
positive regulation of t cell activationGO:00508701010.030
myeloid cell homeostasisGO:00022621140.030
dna conformation changeGO:0071103370.030
anatomical structure homeostasisGO:00602491450.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.030
positive regulation of leukocyte differentiationGO:1902107860.030
multicellular organismal signalingGO:0035637910.029
cellular response to cytokine stimulusGO:00713451890.029
skin developmentGO:00435882200.029
apoptotic signaling pathwayGO:00971903060.029
regulation of proteolysisGO:00301621640.029
regulation of mitotic cell cycleGO:00073461260.029
lymphocyte activation involved in immune responseGO:0002285930.028
negative regulation of cell cycle processGO:0010948690.028
somatic recombination of immunoglobulin gene segmentsGO:0016447420.028
lymphocyte mediated immunityGO:00024491390.028
development of primary sexual characteristicsGO:00451371430.028
regulation of dna recombinationGO:0000018340.028
male gamete generationGO:00482322850.027
retina development in camera type eyeGO:00600411190.027
meiotic chromosome segregationGO:0045132190.027
ossificationGO:00015032160.027
regulation of cellular ketone metabolic processGO:0010565660.027
negative regulation of cell cycle phase transitionGO:1901988480.026
negative regulation of mitotic cell cycleGO:0045930580.026
regulation of lymphocyte differentiationGO:00456191070.026
innate immune responseGO:00450871570.026
leukocyte chemotaxisGO:0030595690.026
cell divisionGO:00513011200.026
extracellular matrix dependent thymocyte migrationGO:007268010.026
neuron apoptotic processGO:00514021420.026
myeloid cell differentiationGO:00300992330.026
protein processingGO:00164851630.026
negative regulation of immune system processGO:00026832090.025
cell recognitionGO:0008037830.025
adaptive immune responseGO:00022501550.025
telomere cappingGO:001623340.025
regulation of apoptotic signaling pathwayGO:20012331970.025
negative regulation of cell cycleGO:00457861230.025
guanosine containing compound catabolic processGO:19010691440.025
regulation of t cell activationGO:00508631700.025
positive regulation of endopeptidase activityGO:0010950430.025
t cell activationGO:00421102890.024
cell cell recognitionGO:0009988440.024
heart morphogenesisGO:00030071780.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.024
actin cytoskeleton organizationGO:00300362200.024
fertilizationGO:00095661270.024
regulation of thymocyte migrationGO:200041020.024
regulation of t cell differentiationGO:0045580830.024
alpha beta t cell activationGO:0046631910.023
cellular response to abiotic stimulusGO:0071214560.023
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.023
fibronectin dependent thymocyte migrationGO:007268110.023
regulation of establishment of protein localizationGO:00702011810.023
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.023
nuclear transportGO:00511691390.023
regulation of protein kinase activityGO:00458592320.023
gonad developmentGO:00084061410.023
leukocyte activation involved in immune responseGO:00023661260.022
intrinsic apoptotic signaling pathwayGO:00971931320.022
positive regulation of proteolysisGO:0045862850.022
positive regulation of lymphocyte activationGO:00512511400.022
sensory organ morphogenesisGO:00905962420.022
amine metabolic processGO:0009308450.022
cell type specific apoptotic processGO:00972852680.022
cilium morphogenesisGO:00602711020.022
positive regulation of cytokine productionGO:00018191740.022
regulation of alpha beta t cell activationGO:0046634530.022
protein secretionGO:00093061110.021
eye photoreceptor cell differentiationGO:0001754410.021
germ cell developmentGO:00072811850.021
mapk cascadeGO:00001652810.021
signal transduction involved in dna damage checkpointGO:007242230.021
regulation of cysteine type endopeptidase activityGO:2000116650.021
female gonad developmentGO:0008585710.021
somatic diversification of immunoglobulinsGO:0016445430.021
organelle localizationGO:00516401790.020
dna catabolic processGO:0006308190.020
spermatogenesisGO:00072832840.020
negative regulation of organelle organizationGO:0010639900.020
leukocyte proliferationGO:00706611720.020
regulation of transferase activityGO:00513382630.020
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.020
positive regulation of programmed cell deathGO:00430682180.020
positive regulation of peptidase activityGO:0010952490.020
positive regulation of kinase activityGO:00336741550.020
meiotic dna repair synthesisGO:000071140.020
thymocyte apoptotic processGO:0070242190.020
female sex differentiationGO:0046660840.020
nucleocytoplasmic transportGO:00069131390.019
negative regulation of cellular amine metabolic processGO:003323910.019
b cell activation involved in immune responseGO:0002312500.019
positive regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030910.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
purine ribonucleoside monophosphate catabolic processGO:0009169570.019
epithelial cell proliferationGO:00506731740.019
dna catabolic process endonucleolyticGO:0000737150.019
transmembrane transportGO:00550854120.019
single fertilizationGO:0007338820.018
negative regulation of dna recombinationGO:0045910130.018
microtubule based processGO:00070172360.018
regulation of secretionGO:00510462740.018
negative regulation of dna replicationGO:000815640.018
alpha beta t cell differentiationGO:0046632690.018
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.018
cell chemotaxisGO:0060326810.018
multicellular organismal homeostasisGO:00488711640.018
prevention of polyspermyGO:006046840.018
spleen developmentGO:0048536390.018
lymphocyte apoptotic processGO:0070227540.018
stem cell differentiationGO:00488632680.017
regulation of protein localizationGO:00328802310.017
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.017
embryonic organ morphogenesisGO:00485622760.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.017
regulation of t cell proliferationGO:0042129920.017
thymocyte migrationGO:007267920.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
activation of cysteine type endopeptidase activityGO:0097202270.017
camera type eye developmentGO:00430102660.017
immunoglobulin mediated immune responseGO:0016064690.017
myeloid leukocyte migrationGO:0097529570.017
somatic diversification of immune receptors via somatic mutationGO:000256680.017
positive regulation of membrane protein ectodomain proteolysisGO:005104430.017
gliogenesisGO:00420631410.017
positive regulation of cysteine type endopeptidase activityGO:2001056390.017
b cell mediated immunityGO:0019724710.017
immune effector processGO:00022523210.017
cellular response to radiationGO:0071478280.017
regulation of leukocyte apoptotic processGO:2000106560.017
epithelial tube morphogenesisGO:00605623030.017
peptidyl amino acid modificationGO:00181933360.017
response to uvGO:0009411440.017
protein modification by small protein conjugationGO:00324461870.016
regulation of myeloid cell differentiationGO:0045637960.016
locomotory behaviorGO:00076261950.016
spermatid developmentGO:00072861080.016
histone modificationGO:00165701590.016
dna dependent dna replicationGO:0006261240.016
neuron deathGO:00709971540.016
regulation of mapk cascadeGO:00434082480.016
stem cell developmentGO:00488642190.016
mitotic cell cycle checkpointGO:0007093310.016
membrane organizationGO:00610242450.016
regulation of lymphocyte proliferationGO:00506701170.016
regulation of cytokine productionGO:00018172660.016
macromolecule methylationGO:00434141200.016
histone lysine methylationGO:0034968500.015
axon ensheathmentGO:0008366760.015
regulation of protein serine threonine kinase activityGO:00719001570.015
regulation of nucleoside metabolic processGO:00091181300.015
tissue homeostasisGO:00018941150.015
chromosome segregationGO:0007059480.015
isotype switchingGO:0045190360.015
ion transmembrane transportGO:00342203610.015
morphogenesis of a branching structureGO:00017632030.015
response to transforming growth factor betaGO:0071559880.015
regulation of membrane protein ectodomain proteolysisGO:005104330.015
regulation of secretion by cellGO:19035302490.015
gland developmentGO:00487323300.015
engulfment of apoptotic cellGO:004365230.015
organelle assemblyGO:00709251770.015
gtp metabolic processGO:00460391440.015
negative regulation of cellular protein metabolic processGO:00322692470.015
germinal center formationGO:0002467160.015
regulation of chromosome organizationGO:0033044830.015
positive regulation of protein phosphorylationGO:00019342420.015
histone h3 k9 methylationGO:0051567170.015
protein catabolic processGO:00301632210.015
rna dependent dna replicationGO:000627830.015
positive regulation of cell deathGO:00109422240.014
immune response regulating signaling pathwayGO:00027641250.014
positive regulation of mitotic cell cycleGO:0045931410.014
cation transportGO:00068123990.014
regulation of fibronectin dependent thymocyte migrationGO:200041310.014
intra s dna damage checkpointGO:003157340.014
negative regulation of intracellular signal transductionGO:19025321670.014
regulation of neuron apoptotic processGO:00435231220.014
pma inducible membrane protein ectodomain proteolysisGO:005108810.014
compound eye developmentGO:004874910.014
positive regulation of glial cell proliferationGO:006025240.014
regulation of t cell apoptotic processGO:0070232280.014
male meiosis iGO:0007141160.014
alpha beta t cell activation involved in immune responseGO:0002287310.014
negative regulation of cellular amino acid metabolic processGO:004576300.013
maintenance of locationGO:0051235890.013
regulation of rho protein signal transductionGO:0035023710.013
regulation of innate immune responseGO:0045088910.013
positive regulation of fibronectin dependent thymocyte migrationGO:200041510.013
microtubule nucleationGO:000702020.013
peptidyl lysine modificationGO:0018205770.013
cardiac chamber developmentGO:00032051080.013
negative regulation of t cell activationGO:0050868650.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.013
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.013
centrosome duplicationGO:0051298160.013
hematopoietic progenitor cell differentiationGO:00022441430.013
t cell differentiation in thymusGO:0033077770.013
positive regulation of protein serine threonine kinase activityGO:00719021060.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
positive regulation of apoptotic signaling pathwayGO:2001235950.013
positive regulation of cellular catabolic processGO:00313311480.013
regulation of nucleotide metabolic processGO:00061401690.013
ensheathment of neuronsGO:0007272760.013
negative regulation of cell activationGO:00508661110.013
digestive tract developmentGO:00485651900.013
covalent chromatin modificationGO:00165691630.013
leukocyte mediated immunityGO:00024431740.013
regulation of peptidase activityGO:0052547960.013
branching morphogenesis of an epithelial tubeGO:00487541590.013
lymphocyte proliferationGO:00466511640.013
signal transduction involved in mitotic dna damage checkpointGO:190240230.013
positive regulation of lymphocyte differentiationGO:0045621610.013
neural precursor cell proliferationGO:00613511210.013
negative regulation of lymphocyte activationGO:0051250910.013
protein autophosphorylationGO:0046777610.013
regulation of purine nucleotide metabolic processGO:19005421690.013
histone methylationGO:0016571710.012
cell fate commitmentGO:00451652100.012
chemotaxisGO:00069352470.012
regulation of cell cycle g2 m phase transitionGO:1902749100.012
dna integrity checkpointGO:0031570280.012
positive regulation of cell activationGO:00508671580.012
eosinophil migrationGO:007267730.012
gene silencingGO:0016458380.012
regulation of lymphocyte mediated immunityGO:0002706840.012
epidermis developmentGO:00085441870.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.012
intestinal epithelial structure maintenanceGO:006072940.012
regulation of cellular response to stressGO:00801351590.012
chromatin silencingGO:0006342150.012
cellular homeostasisGO:00197252400.012
endocytosisGO:00068971680.012
organism emergence from protective structureGO:007168440.012
regulation of thymocyte apoptotic processGO:0070243140.012
regulation of kinase activityGO:00435492490.012
centrosome cycleGO:0007098230.012
dna geometric changeGO:003239270.012
telomere maintenance via telomeraseGO:000700410.012
guanosine containing compound metabolic processGO:19010681440.012
regulation of ras protein signal transductionGO:00465781140.012
regulation of leukocyte proliferationGO:00706631210.011
cell cycle checkpointGO:0000075470.011
response to organonitrogen compoundGO:00102432460.011
striated muscle tissue developmentGO:00147062930.011
regulation of defense responseGO:00313472330.011
glycoprotein metabolic processGO:00091001160.011
negative regulation of cell agingGO:009034450.011
protection from non homologous end joining at telomereGO:003184840.011
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.011
regulation of b cell activationGO:0050864810.011
nephron developmentGO:00720061090.011
skeletal system developmentGO:00015013560.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
ventricular compact myocardium morphogenesisGO:000322320.011
tube formationGO:00351481400.011
internal protein amino acid acetylationGO:0006475420.011
negative regulation of t helper 2 cell differentiationGO:004562940.011
regulation of gtp catabolic processGO:00331241130.011
natural killer cell activationGO:0030101440.011
regulation of endopeptidase activityGO:0052548890.011
regulation of map kinase activityGO:00434051200.011
cell maturationGO:00484691270.011
interleukin 1 alpha secretionGO:005070330.011
response to x rayGO:0010165110.011
cell growthGO:00160491300.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
schwann cell developmentGO:0014044220.011
cytokine secretionGO:0050663720.011
regulation of alpha beta t cell differentiationGO:0046637350.011
positive regulation of nucleotide metabolic processGO:00459811140.011
carbohydrate derivative biosynthetic processGO:19011371830.010
positive regulation of secondary heart field cardioblast proliferationGO:007251340.010
t helper cell differentiationGO:0042093280.010
methylationGO:00322591340.010
cellular response to growth factor stimulusGO:00713631970.010
urogenital system developmentGO:00016552610.010
mrna transcription from rna polymerase ii promoterGO:004278940.010
regulation of sequence specific dna binding transcription factor activityGO:00510901060.010
negative regulation of phosphate metabolic processGO:00459361840.010
innate immune response activating cell surface receptor signaling pathwayGO:000222040.010
dna damage checkpointGO:0000077260.010
myelinationGO:0042552740.010
establishment of organelle localizationGO:00516561220.010
wnt signaling pathwayGO:00160551880.010
establishment or maintenance of cytoskeleton polarityGO:003095220.010
regulation of purine nucleotide catabolic processGO:00331211220.010
central nervous system neuron differentiationGO:00219531620.010
positive regulation of t cell differentiationGO:0045582520.010
regulation of cell projection organizationGO:00313442060.010
regulation of nucleotide catabolic processGO:00308111220.010
divalent inorganic cation homeostasisGO:00725071380.010
somatic hypermutation of immunoglobulin genesGO:001644670.010

Rttn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.070
hematopoietic system diseaseDOID:7400.070
disease of anatomical entityDOID:700.070
anemiaDOID:235500.052
disease of cellular proliferationDOID:1456600.037
aplastic anemiaDOID:1244900.035
congenital hypoplastic anemiaDOID:134200.035
bone marrow diseaseDOID:496100.035
immune system cancerDOID:006008300.034
cancerDOID:16200.034
organ system cancerDOID:005068600.034
hematologic cancerDOID:253100.034
physical disorderDOID:008001500.015
congenital nervous system abnormalityDOID:249000.015
fanconi s anemiaDOID:1363600.013