Mus musculus

68 known processes

Spib

Spi-B transcription factor (Spi-1/PU.1 related)

(Aliases: Spi-B)

Spib biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune response activating signal transductionGO:00027571160.784
lymphocyte differentiationGO:00300982420.779
Mouse
t cell activationGO:00421102890.762
regulation of lymphocyte activationGO:00512492400.727
regulation of cell activationGO:00508652890.688
cytokine productionGO:00018163190.678
immune response activating cell surface receptor signaling pathwayGO:0002429720.661
inflammatory responseGO:00069542440.635
leukocyte proliferationGO:00706611720.624
defense response to other organismGO:00985421970.623
immune response regulating cell surface receptor signaling pathwayGO:0002768800.598
cellular ion homeostasisGO:00068731650.579
regulation of b cell proliferationGO:0030888390.570
activation of immune responseGO:00022531380.554
negative regulation of cell activationGO:00508661110.546
positive regulation of cell activationGO:00508671580.541
response to molecule of bacterial originGO:00022371430.535
innate immune responseGO:00450871570.535
cation homeostasisGO:00550802120.529
regulation of synaptic growth at neuromuscular junctionGO:000858240.527
b cell proliferationGO:0042100530.524
myeloid leukocyte activationGO:0002274830.502
Mouse
positive regulation of t cell activationGO:00508701010.470
cytokine secretionGO:0050663720.456
forebrain developmentGO:00309003020.445
cellular calcium ion homeostasisGO:00068741190.440
negative regulation of synapse assemblyGO:005196430.439
cellular chemical homeostasisGO:00550822150.438
leukocyte differentiationGO:00025213420.436
regulation of homeostatic processGO:00328441820.418
fatty acid biosynthetic processGO:0006633410.410
leukocyte migrationGO:00509001240.399
regulation of cell motilityGO:20001452360.386
negative regulation of defense responseGO:0031348770.385
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.383
t cell differentiationGO:00302171740.383
g protein coupled receptor signaling pathwayGO:00071862430.374
regulation of leukocyte proliferationGO:00706631210.373
cell adhesionGO:00071553290.372
positive regulation of cytokine productionGO:00018191740.367
dendritic cell differentiationGO:0097028260.362
Mouse
adaptive immune responseGO:00022501550.358
positive regulation of cell developmentGO:00107202370.355
microglial cell activation involved in immune responseGO:000228210.352
negative regulation of cell proliferationGO:00082852960.350
myeloid cell differentiationGO:00300992330.349
cellular homeostasisGO:00197252400.340
axonogenesisGO:00074092740.337
cellular divalent inorganic cation homeostasisGO:00725031270.332
regulation of map kinase activityGO:00434051200.329
neuron projection guidanceGO:00974851410.329
regulation of organelle organizationGO:00330432890.319
divalent inorganic cation homeostasisGO:00725071380.316
positive regulation of nervous system developmentGO:00519622210.308
t cell proliferationGO:00420981200.302
regulation of cytokine productionGO:00018172660.297
positive regulation of t cell receptor signaling pathwayGO:005086240.296
mast cell degranulationGO:0043303190.295
regulation of t cell activationGO:00508631700.293
regulation of ion homeostasisGO:2000021640.291
ras protein signal transductionGO:0007265770.288
negative regulation of immune system processGO:00026832090.286
regulation of mast cell activationGO:0033003210.281
cerebral cortex developmentGO:0021987860.281
immune effector processGO:00022523210.280
negative regulation of lymphocyte activationGO:0051250910.277
immune response regulating signaling pathwayGO:00027641250.273
maintenance of locationGO:0051235890.271
positive regulation of cytokine biosynthetic processGO:0042108400.270
lymphocyte proliferationGO:00466511640.269
regulation of protein serine threonine kinase activityGO:00719001570.269
positive regulation of homeostatic processGO:0032846640.266
regulation of anatomical structure sizeGO:00900661780.266
positive regulation of secretionGO:00510471300.261
regulation of secretionGO:00510462740.261
chemotaxisGO:00069352470.260
activation of innate immune responseGO:0002218560.259
regulation of membrane potentialGO:00423911920.253
regulation of toll like receptor 4 signaling pathwayGO:003414340.252
multicellular organismal homeostasisGO:00488711640.248
sequestering of calcium ionGO:0051208180.248
cytosolic calcium ion homeostasisGO:0051480700.247
lymphocyte apoptotic processGO:0070227540.237
olfactory learningGO:000835520.235
activation of mapk activityGO:0000187590.233
regulation of response to woundingGO:19030341890.230
single organismal cell cell adhesionGO:00163371310.229
regulation of neuron projection developmentGO:00109751690.228
actin filament organizationGO:00070151130.225
cellular metal ion homeostasisGO:00068751510.225
regulation of mapk cascadeGO:00434082480.224
regulation of secretion by cellGO:19035302490.224
antigen receptor mediated signaling pathwayGO:0050851640.224
regulation of lymphocyte proliferationGO:00506701170.223
positive regulation of t cell differentiationGO:0045582520.223
helper t cell chemotaxisGO:003570410.220
regulation of cellular component sizeGO:00325351210.220
heart morphogenesisGO:00030071780.219
regulation of eosinophil degranulationGO:004330910.217
regulation of defense responseGO:00313472330.214
b cell homeostasisGO:0001782340.212
alpha beta t cell activationGO:0046631910.211
chemokine mediated signaling pathwayGO:0070098170.211
metal ion homeostasisGO:00550651890.210
exocytosisGO:00068871210.209
actin polymerization or depolymerizationGO:0008154540.207
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.205
bone resorptionGO:0045453380.205
regulation of innate immune responseGO:0045088910.203
positive regulation of innate immune responseGO:0045089800.203
regulation of cell adhesionGO:00301551540.203
glial cell differentiationGO:00100011310.202
regulation of cellular component biogenesisGO:00440871810.202
leukocyte chemotaxisGO:0030595690.196
granulocyte migrationGO:0097530430.195
negative regulation of lymphocyte proliferationGO:0050672450.192
cd8 positive alpha beta t cell extravasationGO:003569730.191
eosinophil activationGO:004330710.191
axon guidanceGO:00074111410.188
regulation of blood coagulationGO:0030193280.187
regulation of leukocyte differentiationGO:19021051590.187
Zebrafish
platelet activationGO:0030168400.185
negative regulation of eosinophil degranulationGO:004331010.184
cation transportGO:00068123990.183
positive regulation of protein secretionGO:0050714520.183
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.183
tissue remodelingGO:00487711020.182
nephric duct formationGO:007217940.178
positive regulation of cell migrationGO:00303351090.177
calcium ion transport into cytosolGO:0060402480.176
action potentialGO:0001508780.176
positive regulation of secretion by cellGO:19035321140.175
interferon gamma productionGO:0032609670.174
membrane organizationGO:00610242450.171
positive regulation of lymphocyte activationGO:00512511400.170
tolerance induction to self antigenGO:000251340.170
t cell differentiation in thymusGO:0033077770.169
calcium ion homeostasisGO:00550741270.167
mast cell activationGO:0045576270.167
positive regulation of cellular component biogenesisGO:0044089940.165
i kappab kinase nf kappab signalingGO:0007249850.164
lipoxin a4 biosynthetic processGO:200130310.163
optic nerve structural organizationGO:002163320.162
positive regulation of podosome assemblyGO:007180330.159
regulation of protein complex assemblyGO:0043254830.156
actin filament bundle assemblyGO:0051017400.155
positive regulation of leukocyte degranulationGO:0043302100.155
regulation of kinase activityGO:00435492490.154
associative learningGO:0008306610.154
negative regulation of homeostatic processGO:0032845710.152
mapk cascadeGO:00001652810.152
monocyte extravasationGO:003569620.152
negative regulation of protein serine threonine kinase activityGO:0071901490.152
regulation of vesicle mediated transportGO:00606271390.150
positive regulation of cell motilityGO:20001471160.150
b cell activationGO:00421131610.150
cognitionGO:00508901490.149
erythrocyte differentiationGO:0030218880.148
Mouse
positive regulation of kinase activityGO:00336741550.148
regulation of lymphocyte apoptotic processGO:0070228410.146
jnk cascadeGO:0007254720.146
negative regulation of toll like receptor signaling pathwayGO:0034122140.145
negative regulation of growthGO:0045926990.145
peptidyl amino acid modificationGO:00181933360.143
positive regulation of cell deathGO:00109422240.142
cellular amino acid metabolic processGO:00065201030.142
anatomical structure homeostasisGO:00602491450.142
regulation of stress activated mapk cascadeGO:0032872690.142
eosinophil activation involved in immune responseGO:000227810.141
positive regulation of mapk cascadeGO:00434101700.141
wound healingGO:00420601570.140
cell substrate adhesionGO:00315891300.140
t cell receptor signaling pathwayGO:0050852460.140
sequestering of metal ionGO:0051238190.139
synapse organizationGO:00508081250.138
coagulationGO:0050817780.138
regulation of endocytosisGO:0030100690.137
regulation of protein kinase activityGO:00458592320.135
hemostasisGO:0007599780.134
response to lipopolysaccharideGO:00324961280.132
regulation of actin cytoskeleton organizationGO:0032956840.130
fc receptor mediated inhibitory signaling pathwayGO:000277410.128
lymphocyte homeostasisGO:0002260640.128
actin cytoskeleton organizationGO:00300362200.127
cell type specific apoptotic processGO:00972852680.127
positive regulation of t cell costimulationGO:200052520.127
interferon beta biosynthetic processGO:004535040.126
gliogenesisGO:00420631410.125
divalent inorganic cation transportGO:00725111780.125
regulation of asymmetric cell divisionGO:000978640.125
t cell extravasationGO:007268340.124
response to transforming growth factor betaGO:0071559880.123
developmental maturationGO:00217001930.123
learning or memoryGO:00076111480.123
mast cell activation involved in immune responseGO:0002279200.122
negative regulation of nervous system developmentGO:00519611560.122
positive regulation of leukocyte differentiationGO:1902107860.121
cytokine biosynthetic processGO:0042089680.121
germ cell developmentGO:00072811850.120
positive regulation of apoptotic processGO:00430652170.119
cytokine mediated signaling pathwayGO:00192211150.119
positive regulation of cytokine secretionGO:0050715410.119
antigen processing and presentationGO:0019882470.119
regulation of inflammatory responseGO:00507271470.119
angiogenesisGO:00015252010.118
Mouse
sensory perceptionGO:00076002450.117
regulation of ras protein signal transductionGO:00465781140.117
b cell receptor signaling pathwayGO:0050853200.117
leukocyte activation involved in immune responseGO:00023661260.116
cytokine metabolic processGO:0042107710.115
lymphocyte mediated immunityGO:00024491390.115
kidney developmentGO:00018222130.114
single organism cell adhesionGO:00986021560.114
regulation of cellular ketone metabolic processGO:0010565660.114
rho protein signal transductionGO:0007266320.113
regulation of leukocyte apoptotic processGO:2000106560.113
small molecule biosynthetic processGO:00442831320.112
cellular response to lipidGO:00713961450.112
regulation of podosome assemblyGO:007180130.111
organelle localizationGO:00516401790.110
regulation of monocyte extravasationGO:200043720.109
positive regulation of transferase activityGO:00513471670.109
positive regulation of cellular amine metabolic processGO:003324050.109
stress activated mapk cascadeGO:0051403800.108
protein secretionGO:00093061110.108
cellular ketone metabolic processGO:0042180840.108
regulation of cytokine secretionGO:0050707610.108
defense response to bacteriumGO:00427421190.106
regulation of acute inflammatory response to antigenic stimulusGO:0002864100.105
regulation of mast cell activation involved in immune responseGO:0033006170.105
positive regulation of mast cell activation involved in immune responseGO:0033008100.105
positive regulation of immunological synapse formationGO:200052210.104
cellular response to transforming growth factor beta stimulusGO:0071560880.103
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.103
negative regulation of intracellular signal transductionGO:19025321670.103
regulation of myeloid cell differentiationGO:0045637960.102
Zebrafish
regulation of bindingGO:00510981110.102
humoral immune responseGO:0006959570.101
regulation of t cell costimulationGO:200052320.101
tissue homeostasisGO:00018941150.101
hematopoietic stem cell migrationGO:003570110.099
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:0019886140.098
regulation of cell projection organizationGO:00313442060.098
regulation of acute inflammatory responseGO:0002673270.098
response to growth factorGO:00708481980.098
thymic t cell selectionGO:0045061220.097
regulation of phospholipase c activityGO:190027430.097
response to peptide hormoneGO:00434341270.097
cell activation involved in immune responseGO:00022631260.097
platelet aggregationGO:0070527200.096
positive regulation of interferon alpha productionGO:003272740.096
regulation of canonical wnt signaling pathwayGO:0060828820.095
negative regulation of molecular functionGO:00440922580.095
regulation of leukocyte degranulationGO:0043300200.095
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.094
muscle tissue developmentGO:00605373080.094
establishment or maintenance of cell polarityGO:0007163860.093
regulation of t cell receptor signaling pathwayGO:0050856210.093
positive regulation of jnk cascadeGO:0046330460.093
multicellular organismal signalingGO:0035637910.093
response to testosteroneGO:003357430.093
response to interferon gammaGO:0034341340.092
regulation of t cell differentiationGO:0045580830.092
establishment of organelle localizationGO:00516561220.091
regulation of body fluid levelsGO:00508781620.091
cell growthGO:00160491300.091
positive regulation of immune effector processGO:00026991070.091
negative regulation of b cell activationGO:0050869270.091
leukocyte apoptotic processGO:0071887710.090
oligodendrocyte differentiationGO:0048709530.089
regulation of interleukin 8 productionGO:003267730.089
gland developmentGO:00487323300.088
regulation of hormone levelsGO:00108172110.088
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.088
negative regulation of protein metabolic processGO:00512482820.088
regulation of cellular amine metabolic processGO:0033238200.087
regulation of calcium ion transport into cytosolGO:0010522310.087
learningGO:0007612980.087
sphingosine 1 phosphate signaling pathwayGO:000337630.087
negative regulation of cell developmentGO:00107211690.086
cellular response to biotic stimulusGO:0071216920.086
alpha beta t cell differentiationGO:0046632690.086
innate immune response activating signal transductionGO:0002758500.086
circulatory system processGO:00030131970.086
positive regulation of map kinase activityGO:0043406840.086
tumor necrosis factor superfamily cytokine productionGO:0071706510.086
regulation of ion transportGO:00432692150.085
regulation of t cell extravasationGO:200040730.085
cellular lipid metabolic processGO:00442553230.085
developmental cell growthGO:0048588840.084
response to acid chemicalGO:00011011110.083
macromolecule catabolic processGO:00090572810.083
cell chemotaxisGO:0060326810.083
regulation of protein secretionGO:0050708820.082
sensory organ morphogenesisGO:00905962420.082
positive regulation of protein phosphorylationGO:00019342420.082
positive regulation of leukocyte apoptotic processGO:2000108210.081
interleukin 1 beta productionGO:0032611300.081
negative regulation of response to woundingGO:1903035770.081
negative regulation of leukocyte proliferationGO:0070664460.081
regulation of interferon gamma productionGO:0032649570.081
substrate adhesion dependent cell spreadingGO:0034446300.081
regulation of actin filament based processGO:0032970990.080
neuron migrationGO:00017641220.080
regulation of cytokine biosynthetic processGO:0042035590.080
leukocyte mediated immunityGO:00024431740.080
ensheathment of neuronsGO:0007272760.079
myeloid cell activation involved in immune responseGO:0002275340.079
regulation of hemostasisGO:1900046280.078
cell fate commitmentGO:00451652100.078
regulation of neuron differentiationGO:00456642810.077
regulation of wound healingGO:0061041400.077
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.077
mast cell proliferationGO:007066240.077
lymphocyte migrationGO:0072676260.076
regulation of transferase activityGO:00513382630.076
regulation of cytoskeleton organizationGO:00514931220.076
homeostasis of number of cellsGO:00488722100.076
Mouse
cellularizationGO:000734910.076
establishment of endothelial blood brain barrierGO:001404530.075
cellular response to molecule of bacterial originGO:0071219830.075
positive regulation of neuron differentiationGO:00456661410.075
organelle assemblyGO:00709251770.075
organic acid biosynthetic processGO:0016053860.075
t helper 17 cell chemotaxisGO:003570510.074
neural precursor cell proliferationGO:00613511210.074
regulation of t cell proliferationGO:0042129920.074
divalent metal ion transportGO:00708381720.074
toll like receptor signaling pathwayGO:0002224380.074
positive regulation of protein transportGO:0051222930.074
tumor necrosis factor biosynthetic processGO:0042533100.073
telencephalon developmentGO:00215371860.073
phosphatidylinositol 3 kinase signalingGO:0014065360.073
protein methylationGO:0006479810.073
positive regulation of protein serine threonine kinase activityGO:00719021060.072
regulation of cellular amino acid metabolic processGO:000652150.072
positive regulation of lymphocyte differentiationGO:0045621610.071
microtubule based processGO:00070172360.071
positive regulation of protein modification processGO:00314012990.071
positive regulation of cardioblast differentiationGO:005189130.070
motor neuron axon guidanceGO:0008045260.070
cellular response to growth factor stimulusGO:00713631970.069
positive regulation of protein kinase activityGO:00458601440.069
negative regulation of t cell proliferationGO:0042130380.069
microtubule cytoskeleton organizationGO:00002261570.069
response to extracellular stimulusGO:00099911270.069
immune complex clearanceGO:000243420.069
positive regulation of regulated secretory pathwayGO:1903307100.069
small gtpase mediated signal transductionGO:0007264970.067
epidermis developmentGO:00085441870.067
cardiac muscle tissue developmentGO:00487381300.067
phagocytosisGO:0006909660.067
ameboidal type cell migrationGO:00016671280.067
leukocyte degranulationGO:0043299270.067
regulation of coagulationGO:0050818310.066
regulation of mast cell degranulationGO:0043304160.066
leukocyte homeostasisGO:0001776790.066
immune complex clearance by monocytes and macrophagesGO:000243620.066
positive regulation of cell adhesionGO:0045785800.066
wnt signaling pathwayGO:00160551880.066
regulation of interleukin 1 productionGO:0032652260.066
endomembrane system organizationGO:00102561470.066
negative regulation of kinase activityGO:0033673810.066
intracellular receptor signaling pathwayGO:0030522740.066
osteoclast differentiationGO:0030316620.065
microglia differentiationGO:001400420.065
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.065
negative regulation of t cell activationGO:0050868650.065
carbohydrate homeostasisGO:00335001280.064
mitotic cell cycle processGO:19030471590.064
acute inflammatory responseGO:0002526410.064
tumor necrosis factor productionGO:0032640500.064
axon ensheathmentGO:0008366760.064
myd88 independent toll like receptor signaling pathwayGO:000275630.063
regulation of b cell activationGO:0050864810.063
positive regulation of defense responseGO:00313491240.063
positive regulation of cytosolic calcium ion concentrationGO:0007204650.063
negative regulation of leukocyte differentiationGO:1902106510.062
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.062
regulation of lipid metabolic processGO:00192161180.062
mast cell mediated immunityGO:0002448200.061
regulation of intracellular transportGO:00323861590.061
regulation of antigen receptor mediated signaling pathwayGO:0050854290.061
immunoglobulin mediated immune responseGO:0016064690.061
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.061
positive regulation of wnt signaling pathwayGO:0030177450.061
regulation of rho protein signal transductionGO:0035023710.060
negative regulation of cellular component organizationGO:00511291940.060
transmission of nerve impulseGO:0019226760.060
positive regulation of neuron projection developmentGO:0010976790.060
branching involved in mammary gland duct morphogenesisGO:0060444270.060
regulation of tumor necrosis factor biosynthetic processGO:0042534100.060
stimulatory c type lectin receptor signaling pathwayGO:000222320.060
renal system developmentGO:00720012250.060
synaptic transmissionGO:00072683290.059
myeloid leukocyte mediated immunityGO:0002444420.059
protein kinase b signalingGO:0043491740.059
glycoprotein metabolic processGO:00091001160.059
regulation of cell cycle processGO:00105641600.058
ossificationGO:00015032160.058
oogenesisGO:0048477560.058
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.058
hormone secretionGO:00468791280.057
regulation of adaptive immune responseGO:0002819900.057
carbohydrate transportGO:0008643620.057
positive regulation of tyrosine phosphorylation of stat5 proteinGO:004252360.057
neuronal action potentialGO:0019228540.057
epithelial tube morphogenesisGO:00605623030.056
Mouse
regulation of epithelial cell proliferationGO:00506781410.056
cell recognitionGO:0008037830.056
blood coagulationGO:0007596760.056
neurohypophysis developmentGO:002198520.055
negative regulation of inflammatory responseGO:0050728610.055
fc receptor mediated stimulatory signaling pathwayGO:000243140.055
negative regulation of erk1 and erk2 cascadeGO:0070373210.055
positive regulation of exocytosisGO:0045921200.055
immune response inhibiting signal transductionGO:000276540.055
muscle tissue morphogenesisGO:0060415530.055
regulation of platelet activationGO:0010543170.055
positive regulation of protein complex assemblyGO:0031334450.054
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.054
inner ear morphogenesisGO:00424721010.054
positive regulation of phospholipase c activityGO:001086320.054
eosinophil mediated immunityGO:000244710.054
negative regulation of phosphate metabolic processGO:00459361840.053
regulated secretory pathwayGO:0045055320.053
negative regulation of multi organism processGO:0043901680.053
phospholipid metabolic processGO:0006644870.053
response to ethanolGO:0045471180.053
canonical wnt signaling pathwayGO:00600701300.052
positive regulation of purine nucleotide catabolic processGO:0033123880.052
cellular amine metabolic processGO:0044106440.052
mature dendritic cell differentiationGO:009702930.052
positive regulation of acute inflammatory responseGO:0002675160.052
positive regulation of interferon gamma productionGO:0032729390.051
organelle fissionGO:00482851700.051
regulation of exocytosisGO:0017157610.051
granulocyte chemotaxisGO:0071621390.051
negative regulation of myeloid leukocyte differentiationGO:0002762200.051
cell junction organizationGO:0034330770.051
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.051
extracellular structure organizationGO:00430621480.051
regulation of ossificationGO:00302781120.051
skin developmentGO:00435882200.051
positive regulation of t cell extravasationGO:200040920.051
regulation of homotypic cell cell adhesionGO:0034110130.051
regulation of actin polymerization or depolymerizationGO:0008064450.051
negative regulation of cytokine productionGO:0001818840.050
digestive tract developmentGO:00485651900.050
metanephric loop of henle developmentGO:007223640.050
regulation of protein catabolic processGO:00421761080.050
telencephalon cell migrationGO:0022029550.050
negative regulation of phosphorylationGO:00423261660.049
regulation of vasculature developmentGO:1901342880.049
regulation of erythrocyte differentiationGO:0045646230.049
myeloid leukocyte migrationGO:0097529570.049
interleukin 4 productionGO:0032633240.049
positive regulation of stress activated mapk cascadeGO:0032874480.049
oxidation reduction processGO:00551143420.049
positive regulation of organelle organizationGO:00106381280.048
cellular extravasationGO:0045123170.048
positive regulation of b cell receptor signaling pathwayGO:005086140.048
positive regulation of hematopoietic stem cell migrationGO:200047310.047
cellular response to extracellular stimulusGO:0031668810.047
protein catabolic processGO:00301632210.046
insulin secretionGO:0030073890.046
regulation of cellular response to growth factor stimulusGO:0090287820.046
digestive tract morphogenesisGO:00485461470.046
positive regulation of dendritic cell chemotaxisGO:200051010.045
negative regulation of transferase activityGO:0051348850.045
microglia developmentGO:001400520.045
release of sequestered calcium ion into cytosolGO:0051209420.045
t cell selectionGO:0045058340.045
glial cell developmentGO:0021782540.045
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.044
negative regulation of mapk cascadeGO:0043409650.044
formation of primary germ layerGO:0001704770.044
cell maturationGO:00484691270.044
negative regulation of map kinase activityGO:0043407340.044
nitrogen compound transportGO:00717052710.044
positive regulation of lymphocyte proliferationGO:0050671700.044
regulation of bone resorptionGO:0045124240.043
regulation of dendritic cell apoptotic processGO:200066830.043
regulation of blood pressureGO:0008217930.043
negative regulation of b cell proliferationGO:0030889130.043
regulation of jnk cascadeGO:0046328620.043
cardiac muscle tissue growth involved in heart morphogenesisGO:000324510.043
positive regulation of interleukin 8 secretionGO:200048410.043
positive regulation of hydrolase activityGO:00513451480.042
regulation of calcium mediated signalingGO:0050848190.042
positive regulation of leukocyte proliferationGO:0070665730.042
regulation of synapse assemblyGO:0051963290.042
protein autophosphorylationGO:0046777610.041

Spib disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
primary immunodeficiency diseaseDOID:61200.260
immune system diseaseDOID:291400.260
disease of anatomical entityDOID:700.260
blood protein diseaseDOID:62000.095
hematopoietic system diseaseDOID:7400.095
musculoskeletal system diseaseDOID:1700.042