Mus musculus

0 known processes

Pld3

phospholipase D family, member 3

(Aliases: Sam-9)

Pld3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.507
sphingolipid metabolic processGO:0006665450.395
lytic vacuole organizationGO:0080171210.242
lysosome organizationGO:0007040210.216
vacuole organizationGO:0007033380.177
ion transmembrane transportGO:00342203610.176
organelle assemblyGO:00709251770.159
locomotory behaviorGO:00076261950.136
central nervous system neuron differentiationGO:00219531620.134
positive regulation of necrotic cell deathGO:001094010.125
autophagic vacuole assemblyGO:0000045130.116
apoptotic signaling pathwayGO:00971903060.115
cellular amino acid metabolic processGO:00065201030.113
cellular metal ion homeostasisGO:00068751510.108
camera type eye developmentGO:00430102660.098
cellular lipid catabolic processGO:0044242520.097
carbohydrate derivative catabolic processGO:19011362310.096
cellular ion homeostasisGO:00068731650.094
cellular component assembly involved in morphogenesisGO:00109271390.094
renin angiotensin regulation of aldosterone productionGO:000201830.093
regulation of cellular amino acid metabolic processGO:000652150.092
negative regulation of cellular component organizationGO:00511291940.089
epidermis developmentGO:00085441870.087
lipid catabolic processGO:0016042690.085
membrane lipid metabolic processGO:0006643530.084
calcium ion homeostasisGO:00550741270.083
establishment of melanosome localizationGO:0032401110.083
metal ion homeostasisGO:00550651890.082
response to organic cyclic compoundGO:00140701980.082
meiotic cell cycleGO:00513211220.082
maintenance of locationGO:0051235890.079
cellular divalent inorganic cation homeostasisGO:00725031270.074
regulation of cell projection organizationGO:00313442060.073
retina development in camera type eyeGO:00600411190.072
meiotic cell cycle processGO:1903046770.069
rho protein signal transductionGO:0007266320.068
positive regulation of cellular amine metabolic processGO:003324050.067
divalent inorganic cation transportGO:00725111780.065
cellular ketone metabolic processGO:0042180840.064
regulation of protein localizationGO:00328802310.063
regulation of cellular ketone metabolic processGO:0010565660.062
cellular response to nutrient levelsGO:0031669640.060
cation homeostasisGO:00550802120.060
protein processingGO:00164851630.059
phospholipid metabolic processGO:0006644870.059
positive regulation of cellular amino acid metabolic processGO:004576430.058
regulation of organelle organizationGO:00330432890.057
cellular chemical homeostasisGO:00550822150.057
golgi to endosome transportGO:000689530.054
endocytosisGO:00068971680.053
Mouse
cellular homeostasisGO:00197252400.053
cellular amine metabolic processGO:0044106440.053
positive regulation of kinase activityGO:00336741550.052
glycerolipid metabolic processGO:00464861220.050
regulation of establishment of protein localizationGO:00702011810.050
regulation of bindingGO:00510981110.049
sequestering of metal ionGO:0051238190.049
sensory system developmentGO:004888030.049
calcium ion transportGO:00068161590.049
regulation of cellular amine metabolic processGO:0033238200.048
regulation of lipid metabolic processGO:00192161180.046
divalent inorganic cation homeostasisGO:00725071380.045
organelle fissionGO:00482851700.045
actin polymerization or depolymerizationGO:0008154540.045
central nervous system neuron axonogenesisGO:0021955280.044
cytosolic calcium ion transportGO:0060401480.044
macroautophagyGO:0016236210.044
positive regulation of programmed cell deathGO:00430682180.042
negative regulation of nervous system developmentGO:00519611560.042
renal system developmentGO:00720012250.041
ceramide metabolic processGO:0006672310.041
peripheral nervous system developmentGO:0007422530.041
meiotic nuclear divisionGO:00071261150.041
sphingoid metabolic processGO:004651950.040
chemotaxisGO:00069352470.039
positive regulation of protein modification processGO:00314012990.039
macromolecule catabolic processGO:00090572810.039
inorganic cation transmembrane transportGO:00986622070.039
organonitrogen compound catabolic processGO:19015652640.039
kidney developmentGO:00018222130.038
glycosyl compound metabolic processGO:19016572460.038
cellular pigmentationGO:0033059200.038
developmental maturationGO:00217001930.037
amine metabolic processGO:0009308450.037
cell type specific apoptotic processGO:00972852680.037
skin developmentGO:00435882200.036
negative regulation of vesicle fusionGO:003133910.035
cilium morphogenesisGO:00602711020.035
proteolysis involved in cellular protein catabolic processGO:00516031470.035
cellular response to extracellular stimulusGO:0031668810.034
nucleobase containing small molecule metabolic processGO:00550863520.034
neuronal action potentialGO:0019228540.034
regulation of blood pressureGO:0008217930.033
cation transmembrane transportGO:00986552660.033
leukocyte chemotaxisGO:0030595690.033
regulation of transferase activityGO:00513382630.032
asymmetric neuroblast divisionGO:005505910.032
cytoplasmic transportGO:00164822340.032
regulation of transpositionGO:001052820.032
glycosylceramide metabolic processGO:000667740.031
heterochromatin assemblyGO:003150720.030
neuron projection guidanceGO:00974851410.029
negative regulation of gene silencingGO:006096920.029
germ cell developmentGO:00072811850.028
regulation of anatomical structure sizeGO:00900661780.028
lipid biosynthetic processGO:00086101790.028
negative regulation of apoptotic signaling pathwayGO:20012341040.028
negative regulation of chromatin silencingGO:003193610.028
organelle localizationGO:00516401790.028
regulation of arp2 3 complex mediated actin nucleationGO:003431510.028
cell divisionGO:00513011200.028
phospholipid transfer to membraneGO:000664920.027
glycolipid metabolic processGO:0006664250.027
negative regulation of neuron deathGO:1901215980.027
male gamete generationGO:00482322850.027
single fertilizationGO:0007338820.027
organic anion transportGO:00157111370.026
ribonucleotide catabolic processGO:00092612080.026
positive regulation of cytoskeleton organizationGO:0051495490.026
sensory organ morphogenesisGO:00905962420.026
ribonucleotide metabolic processGO:00092592910.026
cellular carbohydrate metabolic processGO:00442621190.026
regulation of protein kinase activityGO:00458592320.025
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.025
lateral line system developmentGO:004892510.025
regulation of cytoplasmic transportGO:19036491120.025
response to extracellular stimulusGO:00099911270.025
blood circulationGO:00080151950.025
vesicle localizationGO:0051648860.024
regulation of neuron apoptotic processGO:00435231220.024
cellular calcium ion homeostasisGO:00068741190.024
sequestering of calcium ionGO:0051208180.024
response to starvationGO:0042594650.024
glycosphingolipid catabolic processGO:004647950.024
pigmentationGO:0043473710.023
protein localization to membraneGO:00726571080.023
negative regulation of cell projection organizationGO:0031345560.023
gland developmentGO:00487323300.023
sensory perceptionGO:00076002450.023
nuclear divisionGO:00002801580.023
aromatic compound catabolic processGO:00194392860.023
chromatin modificationGO:00165681870.023
hindbrain developmentGO:00309021280.023
cell chemotaxisGO:0060326810.023
divalent metal ion transportGO:00708381720.023
urogenital system developmentGO:00016552610.022
regulation of cellular component biogenesisGO:00440871810.022
regulation of lymphocyte activationGO:00512492400.022
circulatory system processGO:00030131970.022
regulation of angiotensin metabolic processGO:006017740.022
regulation of chromosome organizationGO:0033044830.022
regulation of neuron differentiationGO:00456642810.022
cellular response to nerve growth factor stimulusGO:199009030.022
nucleotide metabolic processGO:00091173320.021
hepatocyte growth factor receptor signaling pathwayGO:004801230.021
negative regulation of organelle organizationGO:0010639900.021
cell cycle switchingGO:006018410.021
regulation of synaptic growth at neuromuscular junctionGO:000858240.021
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.021
metencephalon developmentGO:0022037890.021
positive regulation of cell developmentGO:00107202370.021
organic acid transportGO:00158491010.021
reactive oxygen species biosynthetic processGO:190340980.021
regulation of metal ion transportGO:00109591060.020
adult locomotory behaviorGO:0008344910.020
regulation of vesicle mediated transportGO:00606271390.020
modification dependent macromolecule catabolic processGO:00436321330.020
regulation of vesicle fusionGO:003133860.020
regulation of chromatin modificationGO:1903308570.020
cellular response to abiotic stimulusGO:0071214560.020
attachment of spindle microtubules to kinetochoreGO:000860840.020
nucleoside phosphate metabolic processGO:00067533380.020
regulation of ion transportGO:00432692150.020
skeletal system developmentGO:00015013560.020
central nervous system neuron developmentGO:0021954670.020
protein localization to cell leading edgeGO:190246310.019
actin filament polymerizationGO:0030041440.019
mechanoreceptor differentiationGO:0042490670.019
response to molecule of bacterial originGO:00022371430.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
response to organonitrogen compoundGO:00102432460.019
adherens junction maintenanceGO:003433410.019
development of primary sexual characteristicsGO:00451371430.019
regulation of systemic arterial blood pressureGO:0003073610.019
response to inorganic substanceGO:0010035960.019
pigment granule localizationGO:0051875130.019
regulation of meiotic cell cycleGO:0051445340.019
ear developmentGO:00435832000.019
necrotic cell deathGO:0070265300.019
cellular protein complex assemblyGO:00436231160.019
carbohydrate metabolic processGO:00059752300.019
calcium ion transmembrane transportGO:0070588850.019
transmembrane transportGO:00550854120.019
response to peptideGO:19016521360.018
ribonucleoside metabolic processGO:00091192450.018
positive regulation of transferase activityGO:00513471670.018
protein catabolic processGO:00301632210.018
regulation of cellular component sizeGO:00325351210.018
microtubule cytoskeleton organizationGO:00002261570.018
axonogenesisGO:00074092740.018
response to metal ionGO:0010038470.018
regulation of homeostatic processGO:00328441820.018
glucose transportGO:0015758560.018
regulation of actin filament polymerizationGO:0030833380.018
hair cell differentiationGO:0035315400.018
ras protein signal transductionGO:0007265770.018
arp2 3 complex mediated actin nucleationGO:003431430.018
oocyte maturationGO:0001556180.018
spermatogenesisGO:00072832840.018
nucleoside triphosphate catabolic processGO:00091432050.018
cerebellar cortex formationGO:0021697220.018
fertilizationGO:00095661270.018
cell maturationGO:00484691270.017
endocrine processGO:0050886390.017
protein localization to organelleGO:00333651850.017
leukocyte migrationGO:00509001240.017
positive regulation of organelle organizationGO:00106381280.017
cellular response to cytokine stimulusGO:00713451890.017
cellular response to growth factor stimulusGO:00713631970.017
positive regulation of protein phosphorylationGO:00019342420.017
positive regulation of apoptotic processGO:00430652170.017
histone modificationGO:00165701590.017
cellular protein catabolic processGO:00442571550.017
multicellular organism growthGO:00352641610.017
hydrogen ion transmembrane transportGO:1902600250.017
chromatin organizationGO:00063252060.017
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathwayGO:1902235110.017
regulation of ion homeostasisGO:2000021640.017
peptidyl amino acid modificationGO:00181933360.017
purine nucleotide metabolic processGO:00061633020.017
purine containing compound metabolic processGO:00725213110.017
regulation of protein transportGO:00512231630.017
uropod organizationGO:003279620.016
synapsisGO:0007129340.016
establishment of vesicle localizationGO:0051650810.016
regulation of cysteine type endopeptidase activityGO:2000116650.016
regulation of cell cycleGO:00517262810.016
retina morphogenesis in camera type eyeGO:0060042450.016
adult behaviorGO:00305341350.016
reactive oxygen species metabolic processGO:0072593840.016
telencephalon developmentGO:00215371860.016
membrane organizationGO:00610242450.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
regulation of response to drugGO:200102320.016
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.016
tissue homeostasisGO:00018941150.016
amino acid transportGO:0006865610.016
cellular carbohydrate catabolic processGO:0044275150.016
neuron apoptotic processGO:00514021420.016
positive regulation of cell cycleGO:0045787920.016
peptide secretionGO:00027901140.016
cellular response to oxidative stressGO:0034599760.016
multicellular organismal signalingGO:0035637910.015
modification by symbiont of host morphology or physiologyGO:004400340.015
heart morphogenesisGO:00030071780.015
synapse organizationGO:00508081250.015
purine ribonucleotide metabolic processGO:00091502900.015
protein maturationGO:00516041760.015
dna metabolic processGO:00062593030.015
regulation of kinase activityGO:00435492490.015
calcium ion transport into cytosolGO:0060402480.015
response to nutrient levelsGO:00316671090.015
organophosphate catabolic processGO:00464342320.015
negative regulation of transpositionGO:001052920.015
synaptic transmissionGO:00072683290.015
regulation of chromatin silencingGO:003193520.015
membrane lipid biosynthetic processGO:0046467320.015
positive regulation of cell motilityGO:20001471160.015
eye photoreceptor cell differentiationGO:0001754410.015
peptidyl lysine modificationGO:0018205770.015
regulation of actin nucleationGO:005112540.015
cerebral cortex developmentGO:0021987860.015
chromosome segregationGO:0007059480.015
peptide metabolic processGO:0006518460.015
acid secretionGO:0046717330.015
regulation of calcium ion transport into cytosolGO:0010522310.015
schwann cell differentiationGO:0014037260.015
purine ribonucleoside metabolic processGO:00461282410.015
regulation of neuron deathGO:19012141340.014
negative regulation of cell developmentGO:00107211690.014
forebrain cell migrationGO:0021885580.014
heterochromatin organizationGO:007082840.014
release of sequestered calcium ion into cytosolGO:0051209420.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
microtubule based processGO:00070172360.014
lipid localizationGO:00108761260.014
female gamete generationGO:0007292740.014
endomembrane system organizationGO:00102561470.014
neuromuscular process controlling balanceGO:0050885590.014
positive regulation of lamellipodium organizationGO:190274530.014
negative regulation of fat cell differentiationGO:0045599360.014
regulation of calcium ion transportGO:0051924690.014
cellular macromolecule catabolic processGO:00442652060.014
heart contractionGO:0060047930.014
regulation of hormone levelsGO:00108172110.014
ceramide catabolic processGO:004651470.014
regulation of chromatin organizationGO:1902275570.014
regulation of proteolysisGO:00301621640.014
covalent chromatin modificationGO:00165691630.013
wound healingGO:00420601570.013
lymphocyte homeostasisGO:0002260640.013
mapk cascadeGO:00001652810.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.013
protein importGO:00170381010.013
cell adhesionGO:00071553290.013
asymmetric stem cell divisionGO:009872230.013
glial cell differentiationGO:00100011310.013
response to copper ionGO:004668830.013
regulation of peptidase activityGO:0052547960.013
positive regulation of cell divisionGO:0051781310.013
anion transportGO:00068201770.013
vegf activated neuropilin signaling pathway involved in axon guidanceGO:190237810.013
positive regulation of lymphocyte activationGO:00512511400.013
retrograde transport endosome to golgiGO:004214720.013
regulation of actin polymerization or depolymerizationGO:0008064450.013
membrane lipid catabolic processGO:004646680.013
neuron projection extensionGO:1990138640.013
regulation of hydrolase activityGO:00513362460.013
negative regulation of cellular catabolic processGO:0031330470.013
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.013
dendrite developmentGO:00163581150.013
defense response to other organismGO:00985421970.013
alcohol metabolic processGO:00060661160.013
regulation of secretionGO:00510462740.013
positive regulation of actin nucleationGO:005112730.013
muscle system processGO:00030121410.013
regulation of endopeptidase activityGO:0052548890.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.012
cation transportGO:00068123990.012
positive regulation of protein acetylationGO:190198590.012
sphingosine metabolic processGO:000667040.012
inner ear receptor cell differentiationGO:0060113610.012
homeostasis of number of cells within a tissueGO:0048873250.012
muscle tissue developmentGO:00605373080.012
ubiquitin dependent protein catabolic processGO:00065111290.012
detection of stimulusGO:0051606840.012
detection of abiotic stimulusGO:0009582600.012
negative regulation of neuron differentiationGO:00456651010.012
regulation of secretion by cellGO:19035302490.012
telencephalon cell migrationGO:0022029550.012
embryonic retina morphogenesis in camera type eyeGO:006005970.012
cytosolic calcium ion homeostasisGO:0051480700.012
positive regulation of chemotaxisGO:0050921380.012
regulation of systemic arterial blood pressure by renin angiotensinGO:0003081200.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
nitrogen compound transportGO:00717052710.012
heterocycle catabolic processGO:00467002800.012
myelination in peripheral nervous systemGO:0022011190.012
positive regulation of macroautophagyGO:001623930.012
heart processGO:0003015940.012
cellular response to external stimulusGO:0071496880.012
response to monosaccharideGO:0034284670.012
anatomical structure homeostasisGO:00602491450.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
cellular glucan metabolic processGO:0006073320.012
purine ribonucleotide catabolic processGO:00091542080.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
reactive nitrogen species metabolic processGO:200105700.012
cell cycle switching mitotic to meiotic cell cycleGO:005172810.012
negative regulation of homeostatic processGO:0032845710.012
posttranscriptional regulation of gene expressionGO:00106081550.011
negative regulation of neuron projection developmentGO:0010977500.011
oligosaccharide metabolic processGO:0009311110.011
triglyceride metabolic processGO:0006641510.011
actin filament bundle assemblyGO:0051017400.011
dna recombinationGO:0006310920.011
organic acid biosynthetic processGO:0016053860.011
organic hydroxy compound metabolic processGO:19016152030.011
vesicle fusionGO:0006906160.011
regulation of purine nucleotide metabolic processGO:19005421690.011
carboxylic acid transportGO:00469421000.011
homeostasis of number of cellsGO:00488722100.011
activation of adenylate cyclase activityGO:000719040.011
proton transportGO:0015992350.011
cellular response to starvationGO:0009267570.011
regulation of angiotensin levels in bloodGO:000200240.011
regulation of apoptotic signaling pathwayGO:20012331970.011
negative regulation of stress fiber assemblyGO:005149740.011
peptide transportGO:00158331330.011
female meiosis chromosome segregationGO:001632110.011
regulation of t cell activationGO:00508631700.011
oligosaccharide catabolic processGO:000931320.011
response to interleukin 4GO:0070670230.011
nucleoside catabolic processGO:00091642060.011
positive regulation of meiotic cell cycleGO:0051446150.011
peptidyl tyrosine phosphorylationGO:00181081430.011
aminoglycan metabolic processGO:0006022340.011
hindbrain morphogenesisGO:0021575460.011
kidney epithelium developmentGO:00720731210.011
organelle fusionGO:0048284280.011
cerebral cortex tangential migration using cell axon interactionsGO:002182430.011
protein ubiquitinationGO:00165671710.011
engulfment of apoptotic cellGO:004365230.011
cellular response to glucose stimulusGO:0071333450.010
ameboidal type cell migrationGO:00016671280.010
regulation of neuron projection developmentGO:00109751690.010
negative regulation of neuron apoptotic processGO:0043524920.010
regulation of histone modificationGO:0031056560.010
sphingolipid catabolic processGO:003014970.010
glycoprotein metabolic processGO:00091001160.010
positive regulation of secretionGO:00510471300.010
positive regulation of bindingGO:0051099490.010
maintenance of protein location in cellGO:0032507200.010
regulation of endocytosisGO:0030100690.010
positive regulation of cell deathGO:00109422240.010
negative regulation of cellular protein metabolic processGO:00322692470.010
glycolipid catabolic processGO:001937750.010
cellular polysaccharide metabolic processGO:0044264380.010
nuclear transportGO:00511691390.010
neutral lipid metabolic processGO:0006638570.010
cellular amino acid catabolic processGO:0009063250.010
regulation of cytokine productionGO:00018172660.010
negative regulation of bindingGO:0051100390.010
positive regulation of protein kinase activityGO:00458601440.010
negative regulation of dna replicationGO:000815640.010
t cell proliferationGO:00420981200.010

Pld3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.442
lysosomal storage diseaseDOID:321100.442
lipid storage diseaseDOID:945500.442
disease of metabolismDOID:001466700.442
nervous system diseaseDOID:86300.187
Human
disease of anatomical entityDOID:700.187
Human
central nervous system diseaseDOID:33100.155
Human
sphingolipidosisDOID:192700.111
cerebral degenerationDOID:144300.038
brain diseaseDOID:93600.038
disease of mental healthDOID:15000.026
Human
artery diseaseDOID:005082800.010
hypertensionDOID:1076300.010
cardiovascular system diseaseDOID:128700.010
essential hypertensionDOID:1082500.010
vascular diseaseDOID:17800.010