Mus musculus

0 known processes

Gzme

granzyme E

(Aliases: MCSP-2,Ctla6,CCP3,Ctla-6)

Gzme biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of angiotensin metabolic processGO:006017740.171
Mouse
granzyme mediated apoptotic signaling pathwayGO:000862610.125
Mouse
regulation of angiotensin levels in bloodGO:000200240.084
Mouse
regulation of microvillus assemblyGO:003253430.083
negative regulation of endothelial cell migrationGO:001059640.077
negative regulation of blood vessel endothelial cell migrationGO:004353730.064
regulation of microvillus organizationGO:003253030.059
cellular ketone metabolic processGO:0042180840.053
amine metabolic processGO:0009308450.048
apoptotic signaling pathwayGO:00971903060.048
Mouse
response to lipopolysaccharideGO:00324961280.046
Mouse
response to molecule of bacterial originGO:00022371430.046
Mouse
peptidyl amino acid modificationGO:00181933360.044
cell adhesionGO:00071553290.044
regulation of cellular ketone metabolic processGO:0010565660.043
protein catabolic processGO:00301632210.043
sensory perceptionGO:00076002450.043
adaptive immune responseGO:00022501550.041
Mouse
cellular amino acid metabolic processGO:00065201030.039
regulation of cellular amino acid metabolic processGO:000652150.036
regulation of defense responseGO:00313472330.035
regulation of cellular amine metabolic processGO:0033238200.034
regulation of lymphocyte activationGO:00512492400.033
positive regulation of cell developmentGO:00107202370.033
cellular amine metabolic processGO:0044106440.033
leukocyte mediated immunityGO:00024431740.033
Mouse
lymphocyte mediated immunityGO:00024491390.033
Mouse
blood vessel morphogenesisGO:00485142850.032
male gamete generationGO:00482322850.032
positive regulation of cellular amino acid metabolic processGO:004576430.031
negative regulation of cellular amine metabolic processGO:003323910.030
spermatogenesisGO:00072832840.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.030
Mouse
immune effector processGO:00022523210.030
Mouse
regulation of transferase activityGO:00513382630.030
killing by host of symbiont cellsGO:0051873110.030
Mouse
macromolecule catabolic processGO:00090572810.029
positive regulation of nervous system developmentGO:00519622210.029
myotube differentiationGO:00149021050.028
positive regulation of protein modification processGO:00314012990.028
disruption of cells of other organism involved in symbiotic interactionGO:0051818130.028
Mouse
striated muscle tissue developmentGO:00147062930.027
synaptic transmissionGO:00072683290.027
cell type specific apoptotic processGO:00972852680.027
neutrophil mediated killing of gram positive bacteriumGO:007094620.026
Mouse
positive regulation of cellular amine metabolic processGO:003324050.026
regulation of cell cycleGO:00517262810.026
skeletal muscle fiber developmentGO:0048741580.025
regulation of kinase activityGO:00435492490.024
protein modification by small protein conjugation or removalGO:00706472070.024
response to organic cyclic compoundGO:00140701980.024
negative regulation of cellular protein metabolic processGO:00322692470.024
negative regulation of growthGO:0045926990.023
Mouse
skeletal muscle organ developmentGO:00605381630.023
cytokine productionGO:00018163190.023
defense response to bacteriumGO:00427421190.023
Mouse
leukocyte mediated cytotoxicityGO:0001909620.023
Mouse
g protein coupled receptor signaling pathwayGO:00071862430.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
disruption by host of symbiont cellsGO:0051852110.023
Mouse
muscle tissue developmentGO:00605373080.022
regulation of membrane potentialGO:00423911920.022
stem cell proliferationGO:00720891170.022
angiogenesisGO:00015252010.022
small gtpase mediated signal transductionGO:0007264970.022
cellular response to organonitrogen compoundGO:00714171450.022
positive regulation of transferase activityGO:00513471670.022
t cell activationGO:00421102890.022
endocrine processGO:0050886390.022
Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.021
regulation of myotube differentiationGO:0010830620.021
single organism cell adhesionGO:00986021560.020
leukocyte differentiationGO:00025213420.020
cellular response to hormone stimulusGO:00328701500.020
negative regulation of cell proliferationGO:00082852960.020
carbohydrate metabolic processGO:00059752300.020
negative regulation of protein metabolic processGO:00512482820.020
protein maturationGO:00516041760.020
positive regulation of kinase activityGO:00336741550.020
regulation of cytokine productionGO:00018172660.019
cellular lipid metabolic processGO:00442553230.019
dephosphorylationGO:00163111290.019
homeostasis of number of cellsGO:00488722100.019
lymphocyte differentiationGO:00300982420.019
regulation of cell projection organizationGO:00313442060.019
negative regulation of vasculature developmentGO:1901343260.018
neutrophil mediated cytotoxicityGO:007094280.018
Mouse
protein processingGO:00164851630.018
regulation of blood pressureGO:0008217930.018
Mouse
regulation of leukocyte differentiationGO:19021051590.018
myotube cell developmentGO:0014904600.018
protein ubiquitinationGO:00165671710.018
placenta developmentGO:00018901400.018
myeloid leukocyte mediated immunityGO:0002444420.017
Mouse
regulation of cellular component biogenesisGO:00440871810.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
t cell mediated immunityGO:0002456500.017
Mouse
positive regulation of protein kinase activityGO:00458601440.017
regulation of cell motilityGO:20001452360.017
nucleobase containing small molecule metabolic processGO:00550863520.017
regulation of homeostatic processGO:00328441820.017
response to peptide hormoneGO:00434341270.017
regulation of proteolysisGO:00301621640.017
negative regulation of cell cycleGO:00457861230.017
protein modification by small protein conjugationGO:00324461870.017
regulation of establishment of protein localizationGO:00702011810.017
cellular protein catabolic processGO:00442571550.017
cell killingGO:0001906670.017
Mouse
neutrophil mediated immunityGO:0002446190.017
Mouse
regulation of cell activationGO:00508652890.017
t cell differentiationGO:00302171740.017
inflammatory responseGO:00069542440.016
positive regulation of cytokine productionGO:00018191740.016
response to growth factorGO:00708481980.016
reactive oxygen species metabolic processGO:0072593840.016
regulation of skeletal muscle fiber developmentGO:0048742360.016
regulation of eosinophil migrationGO:200041620.016
regulation of hormone levelsGO:00108172110.016
Mouse
regulation of protein serine threonine kinase activityGO:00719001570.016
chromatin organizationGO:00063252060.016
compound eye developmentGO:004874910.016
regulation of lymphocyte differentiationGO:00456191070.016
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.016
Mouse
regulation of protein kinase activityGO:00458592320.016
regulation of neural precursor cell proliferationGO:2000177700.016
muscle cell differentiationGO:00426922610.016
purine containing compound metabolic processGO:00725213110.016
tissue homeostasisGO:00018941150.016
regulation of neuron differentiationGO:00456642810.016
regulation of muscle tissue developmentGO:1901861970.016
sensory perception of chemical stimulusGO:0007606510.016
killing of cells of other organismGO:0031640130.016
Mouse
negative regulation of cellular component organizationGO:00511291940.016
regulation of myoblast differentiationGO:0045661290.015
negative regulation of immune system processGO:00026832090.015
multi multicellular organism processGO:00447061090.015
positive regulation of stem cell proliferationGO:2000648590.015
regulation of t cell activationGO:00508631700.015
regulation of innate immune responseGO:0045088910.015
t cell mediated cytotoxicityGO:0001913260.015
Mouse
myeloid cell homeostasisGO:00022621140.015
t cell proliferationGO:00420981200.015
response to light stimulusGO:00094161350.015
regulation of cell adhesionGO:00301551540.015
anatomical structure homeostasisGO:00602491450.015
mapk cascadeGO:00001652810.015
negative regulation of protein modification processGO:00314001630.015
regulation of protein transportGO:00512231630.015
cellular response to organic cyclic compoundGO:0071407870.015
muscle fiber developmentGO:0048747760.015
thymocyte migrationGO:007267920.014
cellular response to cytokine stimulusGO:00713451890.014
regulation of stem cell proliferationGO:0072091780.014
positive regulation of protein phosphorylationGO:00019342420.014
purine ribonucleotide metabolic processGO:00091502900.014
negative regulation of intracellular signal transductionGO:19025321670.014
alpha beta t cell activationGO:0046631910.014
blood circulationGO:00080151950.014
Mouse
muscle cell developmentGO:00550011330.014
regulation of protein catabolic processGO:00421761080.014
reactive nitrogen species metabolic processGO:200105700.014
organic hydroxy compound metabolic processGO:19016152030.014
regulation of apoptotic signaling pathwayGO:20012331970.014
regulation of protein localizationGO:00328802310.014
nucleoside phosphate metabolic processGO:00067533380.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
membrane organizationGO:00610242450.014
negative regulation of protein phosphorylationGO:00019331260.014
oxidation reduction processGO:00551143420.014
fat cell differentiationGO:00454441600.014
modification by host of symbiont morphology or physiologyGO:0051851120.014
Mouse
morphogenesis of a branching structureGO:00017632030.014
chemotaxisGO:00069352470.014
growth of symbiont involved in interaction with hostGO:0044116230.013
Mouse
regulation of organelle organizationGO:00330432890.013
negative regulation of muscle cell differentiationGO:0051148330.013
germ cell developmentGO:00072811850.013
endomembrane system organizationGO:00102561470.013
rho protein signal transductionGO:0007266320.013
response to oxygen levelsGO:0070482620.013
regulation of inflammatory responseGO:00507271470.013
regulation of cell cycle processGO:00105641600.013
gland developmentGO:00487323300.013
modification dependent protein catabolic processGO:00199411330.013
nitrogen compound transportGO:00717052710.013
activation of mapk activity involved in innate immune responseGO:003541920.013
positive regulation of proteolysisGO:0045862850.013
regulation of secretion by cellGO:19035302490.013
ubiquitin dependent protein catabolic processGO:00065111290.013
positive regulation of cell motilityGO:20001471160.013
negative regulation of phosphate metabolic processGO:00459361840.013
peptidyl serine modificationGO:0018209830.013
response to organonitrogen compoundGO:00102432460.013
carbohydrate derivative biosynthetic processGO:19011371830.013
interspecies interaction between organismsGO:0044419830.013
Mouse
ribose phosphate metabolic processGO:00196932910.013
lipid biosynthetic processGO:00086101790.013
multicellular organism growthGO:00352641610.013
embryonic placenta developmentGO:0001892980.013
negative regulation of molecular functionGO:00440922580.013
posttranscriptional regulation of gene expressionGO:00106081550.013
cellular homeostasisGO:00197252400.013
heart morphogenesisGO:00030071780.012
ribonucleotide metabolic processGO:00092592910.012
positive regulation of cellular catabolic processGO:00313311480.012
multicellular organismal homeostasisGO:00488711640.012
regulation of striated muscle cell differentiationGO:0051153810.012
microtubule based processGO:00070172360.012
circulatory system processGO:00030131970.012
Mouse
positive regulation of cell migrationGO:00303351090.012
myoblast differentiationGO:0045445520.012
axon ensheathmentGO:0008366760.012
innate immune responseGO:00450871570.012
cellular chemical homeostasisGO:00550822150.012
regulation of interleukin 10 secretionGO:200117940.012
protein acylationGO:0043543640.012
regulation of cellular catabolic processGO:00313292420.012
monocarboxylic acid metabolic processGO:00327871910.012
regulation of lipid metabolic processGO:00192161180.012
cellular macromolecule catabolic processGO:00442652060.012
immune response regulating signaling pathwayGO:00027641250.012
multicellular organismal signalingGO:0035637910.012
inter male aggressive behaviorGO:000212130.012
regulation of response to woundingGO:19030341890.012
maintenance of locationGO:0051235890.012
extracellular matrix organizationGO:00301981470.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
spermatid developmentGO:00072861080.012
extracellular structure organizationGO:00430621480.012
cell substrate adhesionGO:00315891300.012
response to peptideGO:19016521360.012
activation of immune responseGO:00022531380.012
positive regulation of cell projection organizationGO:0031346950.012
leukocyte apoptotic processGO:0071887710.012
regulation of cellular response to stressGO:00801351590.012
transmission of nerve impulseGO:0019226760.012
histone modificationGO:00165701590.012
b cell activationGO:00421131610.012
intracellular protein transportGO:00068862040.012
detection of chemical stimulus involved in sensory perception of smellGO:005091140.012
regulation of mitotic cell cycleGO:00073461260.012
cellular response to molecule of bacterial originGO:0071219830.011
response to steroid hormoneGO:0048545560.011
negative regulation of multi organism processGO:0043901680.011
Mouse
positive regulation of protein oligomerizationGO:003246140.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
negative regulation of angiogenesisGO:0016525250.011
cytoplasmic transportGO:00164822340.011
positive regulation of eosinophil migrationGO:200041820.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
cellular response to acid chemicalGO:0071229680.011
response to transforming growth factor betaGO:0071559880.011
positive regulation of thymocyte migrationGO:200041220.011
positive regulation of lymphocyte activationGO:00512511400.011
organ regenerationGO:003110020.011
cognitionGO:00508901490.011
purine nucleotide metabolic processGO:00061633020.011
cellular response to peptideGO:1901653920.011
peptidyl tyrosine phosphorylationGO:00181081430.011
cellular response to peptide hormone stimulusGO:0071375920.011
ensheathment of neuronsGO:0007272760.011
hematopoietic progenitor cell differentiationGO:00022441430.011
cellular protein complex assemblyGO:00436231160.011
negative regulation of cell motilityGO:2000146610.011
neuronal action potentialGO:0019228540.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
immune response activating signal transductionGO:00027571160.011
leukocyte migrationGO:00509001240.011
neural precursor cell proliferationGO:00613511210.011
positive regulation of programmed cell deathGO:00430682180.011
regulation of mapk cascadeGO:00434082480.011
connective tissue developmentGO:00614481790.011
epithelial cell developmentGO:00020641590.011
cellular response to lipidGO:00713961450.011
positive regulation of defense responseGO:00313491240.011
glycoprotein metabolic processGO:00091001160.011
regulation of anatomical structure sizeGO:00900661780.011
regulation of purine nucleotide metabolic processGO:19005421690.011
lymphocyte activation involved in immune responseGO:0002285930.011
ras protein signal transductionGO:0007265770.011
lateral inhibitionGO:004633110.011
reactive oxygen species biosynthetic processGO:190340980.011
gonad developmentGO:00084061410.011
ameboidal type cell migrationGO:00016671280.011
sprouting angiogenesisGO:0002040260.011
cellular response to dna damage stimulusGO:00069742070.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.011
Mouse
single organismal cell cell adhesionGO:00163371310.011
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.010
Mouse
camera type eye developmentGO:00430102660.010
action potentialGO:0001508780.010
interaction with symbiontGO:0051702140.010
Mouse
negative regulation of nervous system developmentGO:00519611560.010
cellular carbohydrate metabolic processGO:00442621190.010
regulation of protein oligomerizationGO:003245940.010
myeloid cell differentiationGO:00300992330.010
negative regulation of phosphorus metabolic processGO:00105631840.010
cardiac muscle tissue developmentGO:00487381300.010
alcohol metabolic processGO:00060661160.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
Mouse
response to acid chemicalGO:00011011110.010
leukocyte chemotaxisGO:0030595690.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
covalent chromatin modificationGO:00165691630.010
developmental maturationGO:00217001930.010
regulation of system processGO:00440572000.010
lymphocyte apoptotic processGO:0070227540.010
lymphocyte proliferationGO:00466511640.010
cell growthGO:00160491300.010
response to insulinGO:00328681000.010
glycoprotein biosynthetic processGO:0009101890.010
negative regulation of protein processingGO:0010955790.010
cellular response to growth factor stimulusGO:00713631970.010
negative regulation of lymphocyte activationGO:0051250910.010
organophosphate biosynthetic processGO:00904071220.010
tissue remodelingGO:00487711020.010
positive regulation of cell deathGO:00109422240.010
protein targetingGO:00066051430.010
activation of nf kappab inducing kinase activityGO:000725040.010

Gzme disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
nervous system diseaseDOID:86300.018
disease of metabolismDOID:001466700.011
musculoskeletal system diseaseDOID:1700.011