Mus musculus

176 known processes

Mlst8

MTOR associated protein, LST8 homolog (S. cerevisiae)

(Aliases: AI851821,AA409454,AI505104,Gbl,0610033N12Rik)

Mlst8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of tor signalingGO:003200830.571
Human
rac protein signal transductionGO:0016601130.555
sphingolipid biosynthetic processGO:0030148260.537
ras protein signal transductionGO:0007265770.384
regulation of tor signalingGO:0032006170.338
Human
small gtpase mediated signal transductionGO:0007264970.321
establishment or maintenance of actin cytoskeleton polarityGO:003095010.311
Yeast
cellular amine metabolic processGO:0044106440.295
regulation of rho protein signal transductionGO:0035023710.292
regulation of cellular amino acid metabolic processGO:000652150.277
purine ribonucleoside triphosphate catabolic processGO:00092071990.258
organic cyclic compound catabolic processGO:19013612950.257
guanosine containing compound catabolic processGO:19010691440.256
cellular response to dna damage stimulusGO:00069742070.253
purine nucleoside triphosphate catabolic processGO:00091462030.250
nucleoside catabolic processGO:00091642060.250
guanosine containing compound metabolic processGO:19010681440.249
membrane lipid biosynthetic processGO:0046467320.233
regulation of ras gtpase activityGO:0032318880.225
purine ribonucleotide metabolic processGO:00091502900.222
regulation of rac protein signal transductionGO:0035020190.221
gtp catabolic processGO:00061841430.215
actin cytoskeleton organizationGO:00300362200.202
ribonucleoside triphosphate catabolic processGO:00092031990.202
organophosphate catabolic processGO:00464342320.198
amine metabolic processGO:0009308450.195
negative regulation of nfat protein import into nucleusGO:005153430.193
actin filament polymerizationGO:0030041440.192
regulation of cell cycleGO:00517262810.189
protein polymerizationGO:0051258570.187
regulation of sphingolipid biosynthetic processGO:009015310.185
purine ribonucleoside catabolic processGO:00461302050.184
nucleoside triphosphate catabolic processGO:00091432050.171
membrane lipid metabolic processGO:0006643530.165
glycosyl compound catabolic processGO:19016582060.159
peptidyl amino acid modificationGO:00181933360.154
cellular ketone metabolic processGO:0042180840.154
regulation of response to drugGO:200102320.150
regulation of purine nucleotide metabolic processGO:19005421690.148
purine nucleoside catabolic processGO:00061522050.148
purine nucleotide metabolic processGO:00061633020.144
regulation of actin filament lengthGO:0030832450.144
regulation of cell sizeGO:0008361720.144
Fly
glycosyl compound metabolic processGO:19016572460.143
nucleoside phosphate metabolic processGO:00067533380.143
nucleotide catabolic processGO:00091662170.142
purine nucleoside triphosphate metabolic processGO:00091442260.142
regulation of organelle organizationGO:00330432890.140
regulation of anatomical structure sizeGO:00900661780.135
cellular amino acid metabolic processGO:00065201030.135
macroautophagyGO:0016236210.134
purine containing compound catabolic processGO:00725232130.132
purine ribonucleoside triphosphate metabolic processGO:00092052200.131
positive regulation of organelle organizationGO:00106381280.126
regulation of hydrolase activityGO:00513362460.125
nucleoside metabolic processGO:00091162460.124
sphingolipid metabolic processGO:0006665450.122
organelle assemblyGO:00709251770.121
regulation of cellular component sizeGO:00325351210.118
regulation of cellular ketone metabolic processGO:0010565660.112
rho protein signal transductionGO:0007266320.111
regulation of cellular amine metabolic processGO:0033238200.108
regulation of ras protein signal transductionGO:00465781140.108
ribonucleoside metabolic processGO:00091192450.108
positive regulation of cellular amino acid metabolic processGO:004576430.108
regulation of actin filament polymerizationGO:0030833380.106
regulation of nucleotide metabolic processGO:00061401690.101
nucleoside phosphate catabolic processGO:19012922220.100
gtp metabolic processGO:00460391440.100
positive regulation of cellular amine metabolic processGO:003324050.100
dendrite developmentGO:00163581150.099
regulation of gtp catabolic processGO:00331241130.099
carbohydrate derivative catabolic processGO:19011362310.099
peptidyl tyrosine modificationGO:00182121450.098
regulation of actin cytoskeleton organizationGO:0032956840.095
cellular nitrogen compound catabolic processGO:00442702800.093
ribonucleoside triphosphate metabolic processGO:00091992200.093
cytoplasmic transportGO:00164822340.092
negative regulation of cell sizeGO:004579230.091
axonogenesisGO:00074092740.089
meiotic cell cycleGO:00513211220.087
regulation of cytoskeleton organizationGO:00514931220.085
ribonucleotide metabolic processGO:00092592910.084
regulation of rac gtpase activityGO:0032314130.084
regulation of purine nucleotide catabolic processGO:00331211220.081
establishment or maintenance of cytoskeleton polarityGO:003095220.080
Yeast
positive regulation of actin filament polymerizationGO:0030838260.078
syncytium formation by plasma membrane fusionGO:0000768420.078
tor signalingGO:0031929210.078
Human Yeast Fly
nucleotide metabolic processGO:00091173320.076
purine ribonucleotide catabolic processGO:00091542080.075
response to light stimulusGO:00094161350.075
peptidyl serine modificationGO:0018209830.073
ribonucleoside catabolic processGO:00424542060.073
nuclear divisionGO:00002801580.072
translational initiationGO:0006413240.071
synapse assemblyGO:0007416560.071
intracellular protein transportGO:00068862040.070
organelle fissionGO:00482851700.066
regulation of actin filament based processGO:0032970990.065
regulation of cell projection organizationGO:00313442060.064
regulation of intracellular transportGO:00323861590.064
germ cell developmentGO:00072811850.064
heterocycle catabolic processGO:00467002800.062
dna metabolic processGO:00062593030.062
aromatic compound catabolic processGO:00194392860.061
meiotic nuclear divisionGO:00071261150.061
regulation of cellular component biogenesisGO:00440871810.060
cellular response to nutrient levelsGO:0031669640.060
regulation of protein transportGO:00512231630.059
nucleoside triphosphate metabolic processGO:00091412300.059
microtubule based processGO:00070172360.057
posttranscriptional regulation of gene expressionGO:00106081550.057
regulation of cellular catabolic processGO:00313292420.055
regulation of peptidyl tyrosine phosphorylationGO:0050730930.055
regulation of cytoplasmic transportGO:19036491120.054
positive regulation of protein modification processGO:00314012990.054
regulation of synaptic growth at neuromuscular junctionGO:000858240.053
synapse organizationGO:00508081250.052
regulation of protein localizationGO:00328802310.052
cellular protein complex assemblyGO:00436231160.051
protein importGO:00170381010.051
purine ribonucleoside metabolic processGO:00461282410.050
regulation of establishment of protein localizationGO:00702011810.050
nuclear transportGO:00511691390.049
establishment of protein localization to organelleGO:00725941180.048
regulation of protein complex assemblyGO:0043254830.047
regulation of translationGO:0006417710.047
positive regulation of protein phosphorylationGO:00019342420.046
purine nucleoside metabolic processGO:00422782410.045
nucleobase containing small molecule metabolic processGO:00550863520.045
digestive tract developmentGO:00485651900.045
negative regulation of protein transportGO:0051224460.045
substantia nigra developmentGO:002176220.044
regulation of cell cycle processGO:00105641600.044
negative regulation of cell cycleGO:00457861230.043
peptidyl tyrosine phosphorylationGO:00181081430.043
mitotic cell cycle processGO:19030471590.043
synaptic growth at neuromuscular junctionGO:005112460.043
chemotaxisGO:00069352470.043
cellular response to starvationGO:0009267570.043
ribonucleotide catabolic processGO:00092612080.042
syncytium formationGO:0006949430.042
regulation of cellular response to stressGO:00801351590.041
organonitrogen compound biosynthetic processGO:19015661920.041
compound eye developmentGO:004874910.040
vacuole organizationGO:0007033380.039
regulation of endocytosisGO:0030100690.039
protein localization to organelleGO:00333651850.039
transcription from rna polymerase i promoterGO:0006360130.039
vesicle localizationGO:0051648860.038
regulation of intracellular protein transportGO:0033157820.038
protein modification by small protein conjugation or removalGO:00706472070.038
regulation of protein kinase activityGO:00458592320.038
Yeast
regulation of rho gtpase activityGO:0032319580.038
multicellular organism growthGO:00352641610.037
Worm
regulation of protein import into nucleusGO:0042306520.037
regulation of ribosome biogenesisGO:009006910.037
peptidyl serine phosphorylationGO:0018105740.037
maintenance of locationGO:0051235890.037
Worm
mitotic cell cycleGO:00002781950.036
ribose phosphate metabolic processGO:00196932910.036
establishment of vesicle localizationGO:0051650810.036
reactive oxygen species metabolic processGO:0072593840.036
cell type specific apoptotic processGO:00972852680.036
regulation of nucleotide catabolic processGO:00308111220.036
regulation of lamellipodium assemblyGO:001059130.035
positive regulation of transcription from rna polymerase iii promoterGO:004594510.035
response to extracellular stimulusGO:00099911270.035
feeding behaviorGO:0007631620.035
regulation of nucleocytoplasmic transportGO:0046822730.035
actin filament organizationGO:00070151130.034
actin filament bundle assemblyGO:0051017400.034
response to insulinGO:00328681000.034
protein import into nucleusGO:0006606950.034
organelle localizationGO:00516401790.034
muscle cell differentiationGO:00426922610.034
positive regulation of protein complex assemblyGO:0031334450.033
neuron projection guidanceGO:00974851410.033
single organism nuclear importGO:1902593950.033
nucleocytoplasmic transportGO:00069131390.033
dna repairGO:00062811070.033
axon ensheathmentGO:0008366760.032
myeloid cell differentiationGO:00300992330.032
positive regulation of cellular component biogenesisGO:0044089940.032
regulation of kinase activityGO:00435492490.031
Yeast
nuclear importGO:0051170950.031
regulation of nucleoside metabolic processGO:00091181300.030
negative regulation of intracellular signal transductionGO:19025321670.030
homeostasis of number of cellsGO:00488722100.030
protein processingGO:00164851630.030
response to peptide hormoneGO:00434341270.029
male gamete generationGO:00482322850.029
regulation of reactive oxygen species metabolic processGO:2000377400.029
membrane organizationGO:00610242450.029
transmission of nerve impulseGO:0019226760.029
protein methylationGO:0006479810.029
actomyosin structure organizationGO:0031032560.028
response to acid chemicalGO:00011011110.028
positive regulation of nervous system developmentGO:00519622210.028
regulation of autophagic vacuole assemblyGO:200078540.028
regulation of apoptotic signaling pathwayGO:20012331970.027
neuronal action potentialGO:0019228540.027
microtubule cytoskeleton organizationGO:00002261570.027
cilium morphogenesisGO:00602711020.027
cell fate commitmentGO:00451652100.027
covalent chromatin modificationGO:00165691630.026
regulation of macroautophagyGO:0016241120.026
negative regulation of intracellular transportGO:0032387380.026
cellular component assembly involved in morphogenesisGO:00109271390.026
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.026
purine containing compound metabolic processGO:00725213110.025
positive regulation of lamellipodium organizationGO:190274530.025
protein localization to nucleusGO:00345041210.025
actin cytoskeleton reorganizationGO:0031532210.024
regulation of neuron differentiationGO:00456642810.024
positive regulation of cell projection organizationGO:0031346950.024
myotube differentiationGO:00149021050.024
phagocytosisGO:0006909660.024
proteasomal protein catabolic processGO:0010498980.024
regulation of membrane potentialGO:00423911920.024
negative regulation of protein localization to nucleusGO:1900181230.024
endocytosisGO:00068971680.024
female gamete generationGO:0007292740.024
regulation of myelinationGO:0031641200.024
regulation of protein targetingGO:1903533610.024
negative regulation of nervous system developmentGO:00519611560.023
positive regulation of glial cell proliferationGO:006025240.023
protein catabolic processGO:00301632210.023
histone lysine methylationGO:0034968500.023
digestive system developmentGO:00551232000.023
negative regulation of cytoplasmic transportGO:1903650290.023
cellular lipid metabolic processGO:00442553230.023
regulation of autophagyGO:0010506300.023
negative regulation of ras protein signal transductionGO:0046580180.022
myelinationGO:0042552740.022
spermatogenesisGO:00072832840.022
positive regulation of protein kinase activityGO:00458601440.022
Yeast
positive regulation of cell deathGO:00109422240.022
cellular response to external stimulusGO:0071496880.022
peptidyl threonine phosphorylationGO:0018107310.022
negative regulation of intracellular protein transportGO:0090317270.022
negative regulation of cellular component organizationGO:00511291940.022
response to starvationGO:0042594650.022
autophagic vacuole assemblyGO:0000045130.022
protein kinase b signalingGO:0043491740.021
lipid localizationGO:00108761260.021
Worm
autophagyGO:0006914450.021
protein maturationGO:00516041760.021
regulation of cell growthGO:0001558910.021
Yeast
actin polymerization or depolymerizationGO:0008154540.020
translationGO:0006412930.020
lamellipodium organizationGO:0097581290.020
positive regulation of programmed cell deathGO:00430682180.020
positive regulation of lamellipodium assemblyGO:001059220.020
negative regulation of cellular catabolic processGO:0031330470.020
apoptotic signaling pathwayGO:00971903060.019
engulfment of apoptotic cellGO:004365230.019
development of primary sexual characteristicsGO:00451371430.019
positive regulation of cytoskeleton organizationGO:0051495490.019
regulation of transferase activityGO:00513382630.019
Yeast
regulation of actin polymerization or depolymerizationGO:0008064450.019
protein modification by small protein conjugationGO:00324461870.018
microtubule based movementGO:0007018840.018
regulation of proteolysisGO:00301621640.018
dna damage checkpointGO:0000077260.018
skin developmentGO:00435882200.018
negative regulation of cellular amine metabolic processGO:003323910.018
ribonucleoprotein complex subunit organizationGO:0071826280.018
muscle tissue developmentGO:00605373080.018
response to amino acidGO:0043200370.018
regulation of mitotic cell cycle phase transitionGO:1901990730.018
regulation of vacuole organizationGO:004408840.018
regulation of proteasomal protein catabolic processGO:0061136460.017
regulation of transcription factor import into nucleusGO:0042990240.017
t cell activationGO:00421102890.017
divalent metal ion transportGO:00708381720.017
response to decreased oxygen levelsGO:0036293590.017
regulation of meiotic cell cycleGO:0051445340.017
protein alkylationGO:0008213810.017
negative regulation of macroautophagyGO:001624250.017
cation homeostasisGO:00550802120.017
regulation of protein serine threonine kinase activityGO:00719001570.017
vesicle organizationGO:0016050600.016
cellular homeostasisGO:00197252400.016
establishment of glial blood brain barrierGO:006085720.016
double strand break repairGO:0006302480.016
neural tube developmentGO:00219151600.016
establishment or maintenance of cell polarityGO:0007163860.016
Yeast
ruffle organizationGO:0031529160.016
multicellular organismal signalingGO:0035637910.016
response to nutrient levelsGO:00316671090.016
g1 s transition of mitotic cell cycleGO:0000082570.016
blood vessel morphogenesisGO:00485142850.016
cellular response to extracellular stimulusGO:0031668810.016
establishment of organelle localizationGO:00516561220.016
transcription from rna polymerase iii promoterGO:000638330.016
regulation of myotube differentiationGO:0010830620.016
extrinsic apoptotic signaling pathwayGO:00971911260.016
macromolecule catabolic processGO:00090572810.016
synaptic vesicle transportGO:0048489570.015
striated muscle tissue developmentGO:00147062930.015
nitrogen compound transportGO:00717052710.015
positive regulation of proteolysisGO:0045862850.015
divalent inorganic cation transportGO:00725111780.015
axon guidanceGO:00074111410.015
positive regulation of protein serine threonine kinase activityGO:00719021060.015
protein autophosphorylationGO:0046777610.015
midbrain developmentGO:0030901350.015
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.015
negative regulation of cell cycle processGO:0010948690.015
response to oxygen levelsGO:0070482620.015
response to temperature stimulusGO:0009266550.015
tube formationGO:00351481400.015
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.015
tissue homeostasisGO:00018941150.015
cellular metal ion homeostasisGO:00068751510.015
regulation of actin filament bundle assemblyGO:0032231180.015
regulation of transcription from rna polymerase iii promoterGO:000635920.014
response to peptideGO:19016521360.014
protein targetingGO:00066051430.014
positive regulation of ras protein signal transductionGO:0046579130.014
cation transportGO:00068123990.014
ion transmembrane transportGO:00342203610.014
regulation of mitotic cell cycleGO:00073461260.014
negative regulation of phosphorylationGO:00423261660.014
positive regulation of myotube differentiationGO:0010831240.014
ensheathment of neuronsGO:0007272760.014
spermatid developmentGO:00072861080.014
regulation of protein processingGO:0070613960.014
cellular response to organonitrogen compoundGO:00714171450.014
double strand break repair via homologous recombinationGO:0000724210.014
anatomical structure homeostasisGO:00602491450.014
endomembrane system organizationGO:00102561470.014
cell divisionGO:00513011200.013
regulation of cell projection assemblyGO:0060491380.013
positive regulation of muscle cell differentiationGO:0051149390.013
positive regulation of macroautophagyGO:001623930.013
positive regulation of cellular catabolic processGO:00313311480.013
hematopoietic progenitor cell differentiationGO:00022441430.013
inorganic ion transmembrane transportGO:00986602340.013
sequestering of metal ionGO:0051238190.013
carbohydrate transportGO:0008643620.013
regulation of protein localization to nucleusGO:1900180600.013
mapk cascadeGO:00001652810.013
response to growth factorGO:00708481980.013
protein glycosylationGO:0006486550.013
positive regulation of apoptotic processGO:00430652170.013
regulation of synaptic plasticityGO:0048167870.013
transcription factor import into nucleusGO:0042991260.013
rna processingGO:00063961050.013
negative regulation of organelle organizationGO:0010639900.012
synaptic transmissionGO:00072683290.012
negative regulation of nucleocytoplasmic transportGO:0046823230.012
positive regulation of striated muscle cell differentiationGO:0051155350.012
negative regulation of cell proliferationGO:00082852960.012
purine nucleotide catabolic processGO:00061952110.012
positive regulation of necrotic cell deathGO:001094010.012
establishment of synaptic vesicle localizationGO:0097480570.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
chromosome segregationGO:0007059480.012
oocyte axis specificationGO:000730920.012
regulation of cellular protein catabolic processGO:1903362610.012
retrograde transport endosome to golgiGO:004214720.012
circulatory system processGO:00030131970.012
transmembrane transportGO:00550854120.012
response to organonitrogen compoundGO:00102432460.012
trunk segmentationGO:003529040.012
glycerolipid metabolic processGO:00464861220.012
phospholipid metabolic processGO:0006644870.012
negative regulation of dna replicationGO:000815640.012
oocyte constructionGO:000730820.012
negative regulation of cell cycle phase transitionGO:1901988480.012
response to uvGO:0009411440.012
response to heatGO:0009408270.012
regulation of exit from mitosisGO:000709610.012
carbohydrate derivative biosynthetic processGO:19011371830.012
satellite cell activation involved in skeletal muscle regenerationGO:001490130.012
cellular chemical homeostasisGO:00550822150.012
regulation of vesicle mediated transportGO:00606271390.011
negative regulation of protein phosphorylationGO:00019331260.011
regulation of mapk cascadeGO:00434082480.011
positive regulation of cell cycleGO:0045787920.011
calcium ion transportGO:00068161590.011
cellular response to oxygen levelsGO:0071453200.011
reactive oxygen species biosynthetic processGO:190340980.011
regulation of bindingGO:00510981110.011
fertilizationGO:00095661270.011
regulation of neuron projection developmentGO:00109751690.011
cell cycle checkpointGO:0000075470.011
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.011
embryonic epithelial tube formationGO:00018381300.011
positive regulation of ubiquitin protein transferase activityGO:005144340.011
positive regulation of actin filament bundle assemblyGO:0032233110.011
golgi to endosome transportGO:000689530.011
recombinational repairGO:0000725210.011
response to inorganic substanceGO:0010035960.011
sensory perceptionGO:00076002450.011
cation transmembrane transportGO:00986552660.011
asymmetric neuroblast divisionGO:005505910.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
reactive nitrogen species metabolic processGO:200105700.011
negative regulation of protein import into nucleusGO:0042308210.011
response to radiationGO:00093141650.011
regulation of stress fiber assemblyGO:0051492150.011
negative regulation of synapse assemblyGO:005196430.011
cellular response to amino acid stimulusGO:0071230290.011
sequestering of calcium ionGO:0051208180.011
extracellular matrix organizationGO:00301981470.010
rna splicing via transesterification reactionsGO:0000375430.010
modification dependent protein catabolic processGO:00199411330.010
negative regulation of transcription factor import into nucleusGO:0042992130.010
cytokinetic processGO:003250620.010
asymmetric stem cell divisionGO:009872230.010
spermatid differentiationGO:00485151150.010
stem cell developmentGO:00488642190.010
establishment or maintenance of apical basal cell polarityGO:0035088210.010
carbohydrate metabolic processGO:00059752300.010
blood circulationGO:00080151950.010

Mlst8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.026
disease of anatomical entityDOID:700.026
hematopoietic system diseaseDOID:7400.021
nervous system diseaseDOID:86300.014
anemiaDOID:235500.012