IMP: Integrative Multi-species Prediction

Mus musculus

176 known processes

Mlst8

MTOR associated protein, LST8 homolog (S. cerevisiae)

(Aliases: AI851821,AA409454,AI505104,Gbl,0610033N12Rik)

Entrez: 56716
Ensembl: ENSMUSG00000024142
UniProtKB: Q9DCJ1

Process Predictions
Disease Predictions

Mlst8 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of tor signaling	GO:0032008	3	0.571	Human
rac protein signal transduction	GO:0016601	13	0.555
sphingolipid biosynthetic process	GO:0030148	26	0.537
ras protein signal transduction	GO:0007265	77	0.384
regulation of tor signaling	GO:0032006	17	0.338	Human
small gtpase mediated signal transduction	GO:0007264	97	0.321
establishment or maintenance of actin cytoskeleton polarity	GO:0030950	1	0.311	Yeast
cellular amine metabolic process	GO:0044106	44	0.295
regulation of rho protein signal transduction	GO:0035023	71	0.292
regulation of cellular amino acid metabolic process	GO:0006521	5	0.277
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.258
organic cyclic compound catabolic process	GO:1901361	295	0.257
guanosine containing compound catabolic process	GO:1901069	144	0.256
cellular response to dna damage stimulus	GO:0006974	207	0.253
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.250
nucleoside catabolic process	GO:0009164	206	0.250
guanosine containing compound metabolic process	GO:1901068	144	0.249
membrane lipid biosynthetic process	GO:0046467	32	0.233
regulation of ras gtpase activity	GO:0032318	88	0.225
purine ribonucleotide metabolic process	GO:0009150	290	0.222
regulation of rac protein signal transduction	GO:0035020	19	0.221
gtp catabolic process	GO:0006184	143	0.215
actin cytoskeleton organization	GO:0030036	220	0.202
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.202
organophosphate catabolic process	GO:0046434	232	0.198
amine metabolic process	GO:0009308	45	0.195
negative regulation of nfat protein import into nucleus	GO:0051534	3	0.193
actin filament polymerization	GO:0030041	44	0.192
regulation of cell cycle	GO:0051726	281	0.189
protein polymerization	GO:0051258	57	0.187
regulation of sphingolipid biosynthetic process	GO:0090153	1	0.185
purine ribonucleoside catabolic process	GO:0046130	205	0.184
nucleoside triphosphate catabolic process	GO:0009143	205	0.171
membrane lipid metabolic process	GO:0006643	53	0.165
glycosyl compound catabolic process	GO:1901658	206	0.159
peptidyl amino acid modification	GO:0018193	336	0.154
cellular ketone metabolic process	GO:0042180	84	0.154
regulation of response to drug	GO:2001023	2	0.150
regulation of purine nucleotide metabolic process	GO:1900542	169	0.148
purine nucleoside catabolic process	GO:0006152	205	0.148
purine nucleotide metabolic process	GO:0006163	302	0.144
regulation of actin filament length	GO:0030832	45	0.144
regulation of cell size	GO:0008361	72	0.144	Fly
glycosyl compound metabolic process	GO:1901657	246	0.143
nucleoside phosphate metabolic process	GO:0006753	338	0.143
nucleotide catabolic process	GO:0009166	217	0.142
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.142
regulation of organelle organization	GO:0033043	289	0.140
regulation of anatomical structure size	GO:0090066	178	0.135
cellular amino acid metabolic process	GO:0006520	103	0.135
macroautophagy	GO:0016236	21	0.134
purine containing compound catabolic process	GO:0072523	213	0.132
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.131
positive regulation of organelle organization	GO:0010638	128	0.126
regulation of hydrolase activity	GO:0051336	246	0.125
nucleoside metabolic process	GO:0009116	246	0.124
sphingolipid metabolic process	GO:0006665	45	0.122
organelle assembly	GO:0070925	177	0.121
regulation of cellular component size	GO:0032535	121	0.118
regulation of cellular ketone metabolic process	GO:0010565	66	0.112
rho protein signal transduction	GO:0007266	32	0.111
regulation of cellular amine metabolic process	GO:0033238	20	0.108
regulation of ras protein signal transduction	GO:0046578	114	0.108
ribonucleoside metabolic process	GO:0009119	245	0.108
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.108
regulation of actin filament polymerization	GO:0030833	38	0.106
regulation of nucleotide metabolic process	GO:0006140	169	0.101
nucleoside phosphate catabolic process	GO:1901292	222	0.100
gtp metabolic process	GO:0046039	144	0.100
positive regulation of cellular amine metabolic process	GO:0033240	5	0.100
dendrite development	GO:0016358	115	0.099
regulation of gtp catabolic process	GO:0033124	113	0.099
carbohydrate derivative catabolic process	GO:1901136	231	0.099
peptidyl tyrosine modification	GO:0018212	145	0.098
regulation of actin cytoskeleton organization	GO:0032956	84	0.095
cellular nitrogen compound catabolic process	GO:0044270	280	0.093
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.093
cytoplasmic transport	GO:0016482	234	0.092
negative regulation of cell size	GO:0045792	3	0.091
axonogenesis	GO:0007409	274	0.089
meiotic cell cycle	GO:0051321	122	0.087
regulation of cytoskeleton organization	GO:0051493	122	0.085
ribonucleotide metabolic process	GO:0009259	291	0.084
regulation of rac gtpase activity	GO:0032314	13	0.084
regulation of purine nucleotide catabolic process	GO:0033121	122	0.081
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.080	Yeast
positive regulation of actin filament polymerization	GO:0030838	26	0.078
syncytium formation by plasma membrane fusion	GO:0000768	42	0.078
tor signaling	GO:0031929	21	0.078	Human Yeast Fly
nucleotide metabolic process	GO:0009117	332	0.076
purine ribonucleotide catabolic process	GO:0009154	208	0.075
response to light stimulus	GO:0009416	135	0.075
peptidyl serine modification	GO:0018209	83	0.073
ribonucleoside catabolic process	GO:0042454	206	0.073
nuclear division	GO:0000280	158	0.072
translational initiation	GO:0006413	24	0.071
synapse assembly	GO:0007416	56	0.071
intracellular protein transport	GO:0006886	204	0.070
organelle fission	GO:0048285	170	0.066
regulation of actin filament based process	GO:0032970	99	0.065
regulation of cell projection organization	GO:0031344	206	0.064
regulation of intracellular transport	GO:0032386	159	0.064
germ cell development	GO:0007281	185	0.064
heterocycle catabolic process	GO:0046700	280	0.062
dna metabolic process	GO:0006259	303	0.062
aromatic compound catabolic process	GO:0019439	286	0.061
meiotic nuclear division	GO:0007126	115	0.061
regulation of cellular component biogenesis	GO:0044087	181	0.060
cellular response to nutrient levels	GO:0031669	64	0.060
regulation of protein transport	GO:0051223	163	0.059
nucleoside triphosphate metabolic process	GO:0009141	230	0.059
microtubule based process	GO:0007017	236	0.057
posttranscriptional regulation of gene expression	GO:0010608	155	0.057
regulation of cellular catabolic process	GO:0031329	242	0.055
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.055
regulation of cytoplasmic transport	GO:1903649	112	0.054
positive regulation of protein modification process	GO:0031401	299	0.054
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.053
synapse organization	GO:0050808	125	0.052
regulation of protein localization	GO:0032880	231	0.052
cellular protein complex assembly	GO:0043623	116	0.051
protein import	GO:0017038	101	0.051
purine ribonucleoside metabolic process	GO:0046128	241	0.050
regulation of establishment of protein localization	GO:0070201	181	0.050
nuclear transport	GO:0051169	139	0.049
establishment of protein localization to organelle	GO:0072594	118	0.048
regulation of protein complex assembly	GO:0043254	83	0.047
regulation of translation	GO:0006417	71	0.047
positive regulation of protein phosphorylation	GO:0001934	242	0.046
purine nucleoside metabolic process	GO:0042278	241	0.045
nucleobase containing small molecule metabolic process	GO:0055086	352	0.045
digestive tract development	GO:0048565	190	0.045
negative regulation of protein transport	GO:0051224	46	0.045
substantia nigra development	GO:0021762	2	0.044
regulation of cell cycle process	GO:0010564	160	0.044
negative regulation of cell cycle	GO:0045786	123	0.043
peptidyl tyrosine phosphorylation	GO:0018108	143	0.043
mitotic cell cycle process	GO:1903047	159	0.043
synaptic growth at neuromuscular junction	GO:0051124	6	0.043
chemotaxis	GO:0006935	247	0.043
cellular response to starvation	GO:0009267	57	0.043
ribonucleotide catabolic process	GO:0009261	208	0.042
syncytium formation	GO:0006949	43	0.042
regulation of cellular response to stress	GO:0080135	159	0.041
organonitrogen compound biosynthetic process	GO:1901566	192	0.041
compound eye development	GO:0048749	1	0.040
vacuole organization	GO:0007033	38	0.039
regulation of endocytosis	GO:0030100	69	0.039
protein localization to organelle	GO:0033365	185	0.039
transcription from rna polymerase i promoter	GO:0006360	13	0.039
vesicle localization	GO:0051648	86	0.038
regulation of intracellular protein transport	GO:0033157	82	0.038
protein modification by small protein conjugation or removal	GO:0070647	207	0.038
regulation of protein kinase activity	GO:0045859	232	0.038	Yeast
regulation of rho gtpase activity	GO:0032319	58	0.038
multicellular organism growth	GO:0035264	161	0.037	Worm
regulation of protein import into nucleus	GO:0042306	52	0.037
regulation of ribosome biogenesis	GO:0090069	1	0.037
peptidyl serine phosphorylation	GO:0018105	74	0.037
maintenance of location	GO:0051235	89	0.037	Worm
mitotic cell cycle	GO:0000278	195	0.036
ribose phosphate metabolic process	GO:0019693	291	0.036
establishment of vesicle localization	GO:0051650	81	0.036
reactive oxygen species metabolic process	GO:0072593	84	0.036
cell type specific apoptotic process	GO:0097285	268	0.036
regulation of nucleotide catabolic process	GO:0030811	122	0.036
regulation of lamellipodium assembly	GO:0010591	3	0.035
positive regulation of transcription from rna polymerase iii promoter	GO:0045945	1	0.035
response to extracellular stimulus	GO:0009991	127	0.035
feeding behavior	GO:0007631	62	0.035
regulation of nucleocytoplasmic transport	GO:0046822	73	0.035
actin filament organization	GO:0007015	113	0.034
actin filament bundle assembly	GO:0051017	40	0.034
response to insulin	GO:0032868	100	0.034
protein import into nucleus	GO:0006606	95	0.034
organelle localization	GO:0051640	179	0.034
muscle cell differentiation	GO:0042692	261	0.034
positive regulation of protein complex assembly	GO:0031334	45	0.033
neuron projection guidance	GO:0097485	141	0.033
single organism nuclear import	GO:1902593	95	0.033
nucleocytoplasmic transport	GO:0006913	139	0.033
dna repair	GO:0006281	107	0.033
axon ensheathment	GO:0008366	76	0.032
myeloid cell differentiation	GO:0030099	233	0.032
positive regulation of cellular component biogenesis	GO:0044089	94	0.032
regulation of kinase activity	GO:0043549	249	0.031	Yeast
nuclear import	GO:0051170	95	0.031
regulation of nucleoside metabolic process	GO:0009118	130	0.030
negative regulation of intracellular signal transduction	GO:1902532	167	0.030
homeostasis of number of cells	GO:0048872	210	0.030
protein processing	GO:0016485	163	0.030
response to peptide hormone	GO:0043434	127	0.029
male gamete generation	GO:0048232	285	0.029
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.029
membrane organization	GO:0061024	245	0.029
transmission of nerve impulse	GO:0019226	76	0.029
protein methylation	GO:0006479	81	0.029
actomyosin structure organization	GO:0031032	56	0.028
response to acid chemical	GO:0001101	111	0.028
positive regulation of nervous system development	GO:0051962	221	0.028
regulation of autophagic vacuole assembly	GO:2000785	4	0.028
regulation of apoptotic signaling pathway	GO:2001233	197	0.027
neuronal action potential	GO:0019228	54	0.027
microtubule cytoskeleton organization	GO:0000226	157	0.027
cilium morphogenesis	GO:0060271	102	0.027
cell fate commitment	GO:0045165	210	0.027
covalent chromatin modification	GO:0016569	163	0.026
regulation of macroautophagy	GO:0016241	12	0.026
negative regulation of intracellular transport	GO:0032387	38	0.026
cellular component assembly involved in morphogenesis	GO:0010927	139	0.026
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.026
purine containing compound metabolic process	GO:0072521	311	0.025
positive regulation of lamellipodium organization	GO:1902745	3	0.025
protein localization to nucleus	GO:0034504	121	0.025
actin cytoskeleton reorganization	GO:0031532	21	0.024
regulation of neuron differentiation	GO:0045664	281	0.024
positive regulation of cell projection organization	GO:0031346	95	0.024
myotube differentiation	GO:0014902	105	0.024
phagocytosis	GO:0006909	66	0.024
proteasomal protein catabolic process	GO:0010498	98	0.024
regulation of membrane potential	GO:0042391	192	0.024
negative regulation of protein localization to nucleus	GO:1900181	23	0.024
endocytosis	GO:0006897	168	0.024
female gamete generation	GO:0007292	74	0.024
regulation of myelination	GO:0031641	20	0.024
regulation of protein targeting	GO:1903533	61	0.024
negative regulation of nervous system development	GO:0051961	156	0.023
positive regulation of glial cell proliferation	GO:0060252	4	0.023
protein catabolic process	GO:0030163	221	0.023
histone lysine methylation	GO:0034968	50	0.023
digestive system development	GO:0055123	200	0.023
negative regulation of cytoplasmic transport	GO:1903650	29	0.023
cellular lipid metabolic process	GO:0044255	323	0.023
regulation of autophagy	GO:0010506	30	0.023
negative regulation of ras protein signal transduction	GO:0046580	18	0.022
myelination	GO:0042552	74	0.022
spermatogenesis	GO:0007283	284	0.022
positive regulation of protein kinase activity	GO:0045860	144	0.022	Yeast
positive regulation of cell death	GO:0010942	224	0.022
cellular response to external stimulus	GO:0071496	88	0.022
peptidyl threonine phosphorylation	GO:0018107	31	0.022
negative regulation of intracellular protein transport	GO:0090317	27	0.022
negative regulation of cellular component organization	GO:0051129	194	0.022
response to starvation	GO:0042594	65	0.022
autophagic vacuole assembly	GO:0000045	13	0.022
protein kinase b signaling	GO:0043491	74	0.021
lipid localization	GO:0010876	126	0.021	Worm
autophagy	GO:0006914	45	0.021
protein maturation	GO:0051604	176	0.021
regulation of cell growth	GO:0001558	91	0.021	Yeast
actin polymerization or depolymerization	GO:0008154	54	0.020
translation	GO:0006412	93	0.020
lamellipodium organization	GO:0097581	29	0.020
positive regulation of programmed cell death	GO:0043068	218	0.020
positive regulation of lamellipodium assembly	GO:0010592	2	0.020
negative regulation of cellular catabolic process	GO:0031330	47	0.020
apoptotic signaling pathway	GO:0097190	306	0.019
engulfment of apoptotic cell	GO:0043652	3	0.019
development of primary sexual characteristics	GO:0045137	143	0.019
positive regulation of cytoskeleton organization	GO:0051495	49	0.019
regulation of transferase activity	GO:0051338	263	0.019	Yeast
regulation of actin polymerization or depolymerization	GO:0008064	45	0.019
protein modification by small protein conjugation	GO:0032446	187	0.018
microtubule based movement	GO:0007018	84	0.018
regulation of proteolysis	GO:0030162	164	0.018
dna damage checkpoint	GO:0000077	26	0.018
skin development	GO:0043588	220	0.018
negative regulation of cellular amine metabolic process	GO:0033239	1	0.018
ribonucleoprotein complex subunit organization	GO:0071826	28	0.018
muscle tissue development	GO:0060537	308	0.018
response to amino acid	GO:0043200	37	0.018
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.018
regulation of vacuole organization	GO:0044088	4	0.018
regulation of proteasomal protein catabolic process	GO:0061136	46	0.017
regulation of transcription factor import into nucleus	GO:0042990	24	0.017
t cell activation	GO:0042110	289	0.017
divalent metal ion transport	GO:0070838	172	0.017
response to decreased oxygen levels	GO:0036293	59	0.017
regulation of meiotic cell cycle	GO:0051445	34	0.017
protein alkylation	GO:0008213	81	0.017
negative regulation of macroautophagy	GO:0016242	5	0.017
cation homeostasis	GO:0055080	212	0.017
regulation of protein serine threonine kinase activity	GO:0071900	157	0.017
vesicle organization	GO:0016050	60	0.016
cellular homeostasis	GO:0019725	240	0.016
establishment of glial blood brain barrier	GO:0060857	2	0.016
double strand break repair	GO:0006302	48	0.016
neural tube development	GO:0021915	160	0.016
establishment or maintenance of cell polarity	GO:0007163	86	0.016	Yeast
ruffle organization	GO:0031529	16	0.016
multicellular organismal signaling	GO:0035637	91	0.016
response to nutrient levels	GO:0031667	109	0.016
g1 s transition of mitotic cell cycle	GO:0000082	57	0.016
blood vessel morphogenesis	GO:0048514	285	0.016
cellular response to extracellular stimulus	GO:0031668	81	0.016
establishment of organelle localization	GO:0051656	122	0.016
transcription from rna polymerase iii promoter	GO:0006383	3	0.016
regulation of myotube differentiation	GO:0010830	62	0.016
extrinsic apoptotic signaling pathway	GO:0097191	126	0.016
macromolecule catabolic process	GO:0009057	281	0.016
synaptic vesicle transport	GO:0048489	57	0.015
striated muscle tissue development	GO:0014706	293	0.015
nitrogen compound transport	GO:0071705	271	0.015
positive regulation of proteolysis	GO:0045862	85	0.015
divalent inorganic cation transport	GO:0072511	178	0.015
axon guidance	GO:0007411	141	0.015
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.015
protein autophosphorylation	GO:0046777	61	0.015
midbrain development	GO:0030901	35	0.015
regulation of transcription involved in g1 s transition of mitotic cell cycle	GO:0000083	3	0.015
negative regulation of cell cycle process	GO:0010948	69	0.015
response to oxygen levels	GO:0070482	62	0.015
response to temperature stimulus	GO:0009266	55	0.015
tube formation	GO:0035148	140	0.015
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.015
tissue homeostasis	GO:0001894	115	0.015
cellular metal ion homeostasis	GO:0006875	151	0.015
regulation of actin filament bundle assembly	GO:0032231	18	0.015
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.014
response to peptide	GO:1901652	136	0.014
protein targeting	GO:0006605	143	0.014
positive regulation of ras protein signal transduction	GO:0046579	13	0.014
cation transport	GO:0006812	399	0.014
ion transmembrane transport	GO:0034220	361	0.014
regulation of mitotic cell cycle	GO:0007346	126	0.014
negative regulation of phosphorylation	GO:0042326	166	0.014
positive regulation of myotube differentiation	GO:0010831	24	0.014
ensheathment of neurons	GO:0007272	76	0.014
spermatid development	GO:0007286	108	0.014
regulation of protein processing	GO:0070613	96	0.014
cellular response to organonitrogen compound	GO:0071417	145	0.014
double strand break repair via homologous recombination	GO:0000724	21	0.014
anatomical structure homeostasis	GO:0060249	145	0.014
endomembrane system organization	GO:0010256	147	0.014
cell division	GO:0051301	120	0.013
regulation of cell projection assembly	GO:0060491	38	0.013
positive regulation of muscle cell differentiation	GO:0051149	39	0.013
positive regulation of macroautophagy	GO:0016239	3	0.013
positive regulation of cellular catabolic process	GO:0031331	148	0.013
hematopoietic progenitor cell differentiation	GO:0002244	143	0.013
inorganic ion transmembrane transport	GO:0098660	234	0.013
sequestering of metal ion	GO:0051238	19	0.013
carbohydrate transport	GO:0008643	62	0.013
regulation of protein localization to nucleus	GO:1900180	60	0.013
mapk cascade	GO:0000165	281	0.013
response to growth factor	GO:0070848	198	0.013
protein glycosylation	GO:0006486	55	0.013
positive regulation of apoptotic process	GO:0043065	217	0.013
regulation of synaptic plasticity	GO:0048167	87	0.013
transcription factor import into nucleus	GO:0042991	26	0.013
rna processing	GO:0006396	105	0.013
negative regulation of organelle organization	GO:0010639	90	0.012
synaptic transmission	GO:0007268	329	0.012
negative regulation of nucleocytoplasmic transport	GO:0046823	23	0.012
positive regulation of striated muscle cell differentiation	GO:0051155	35	0.012
negative regulation of cell proliferation	GO:0008285	296	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012
positive regulation of necrotic cell death	GO:0010940	1	0.012
establishment of synaptic vesicle localization	GO:0097480	57	0.012
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.012
chromosome segregation	GO:0007059	48	0.012
oocyte axis specification	GO:0007309	2	0.012
regulation of cellular protein catabolic process	GO:1903362	61	0.012
retrograde transport endosome to golgi	GO:0042147	2	0.012
circulatory system process	GO:0003013	197	0.012
transmembrane transport	GO:0055085	412	0.012
response to organonitrogen compound	GO:0010243	246	0.012
trunk segmentation	GO:0035290	4	0.012
glycerolipid metabolic process	GO:0046486	122	0.012
phospholipid metabolic process	GO:0006644	87	0.012
negative regulation of dna replication	GO:0008156	4	0.012
oocyte construction	GO:0007308	2	0.012
negative regulation of cell cycle phase transition	GO:1901988	48	0.012
response to uv	GO:0009411	44	0.012
response to heat	GO:0009408	27	0.012
regulation of exit from mitosis	GO:0007096	1	0.012
carbohydrate derivative biosynthetic process	GO:1901137	183	0.012
satellite cell activation involved in skeletal muscle regeneration	GO:0014901	3	0.012
cellular chemical homeostasis	GO:0055082	215	0.012
regulation of vesicle mediated transport	GO:0060627	139	0.011
negative regulation of protein phosphorylation	GO:0001933	126	0.011
regulation of mapk cascade	GO:0043408	248	0.011
positive regulation of cell cycle	GO:0045787	92	0.011
calcium ion transport	GO:0006816	159	0.011
cellular response to oxygen levels	GO:0071453	20	0.011
reactive oxygen species biosynthetic process	GO:1903409	8	0.011
regulation of binding	GO:0051098	111	0.011
fertilization	GO:0009566	127	0.011
regulation of neuron projection development	GO:0010975	169	0.011
cell cycle checkpoint	GO:0000075	47	0.011
germline cell cycle switching mitotic to meiotic cell cycle	GO:0051729	1	0.011
embryonic epithelial tube formation	GO:0001838	130	0.011
positive regulation of ubiquitin protein transferase activity	GO:0051443	4	0.011
positive regulation of actin filament bundle assembly	GO:0032233	11	0.011
golgi to endosome transport	GO:0006895	3	0.011
recombinational repair	GO:0000725	21	0.011
response to inorganic substance	GO:0010035	96	0.011
sensory perception	GO:0007600	245	0.011
cation transmembrane transport	GO:0098655	266	0.011
asymmetric neuroblast division	GO:0055059	1	0.011
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.011
reactive nitrogen species metabolic process	GO:2001057	0	0.011
negative regulation of protein import into nucleus	GO:0042308	21	0.011
response to radiation	GO:0009314	165	0.011
regulation of stress fiber assembly	GO:0051492	15	0.011
negative regulation of synapse assembly	GO:0051964	3	0.011
cellular response to amino acid stimulus	GO:0071230	29	0.011
sequestering of calcium ion	GO:0051208	18	0.011
extracellular matrix organization	GO:0030198	147	0.010
rna splicing via transesterification reactions	GO:0000375	43	0.010
modification dependent protein catabolic process	GO:0019941	133	0.010
negative regulation of transcription factor import into nucleus	GO:0042992	13	0.010
cytokinetic process	GO:0032506	2	0.010
asymmetric stem cell division	GO:0098722	3	0.010
spermatid differentiation	GO:0048515	115	0.010
stem cell development	GO:0048864	219	0.010
establishment or maintenance of apical basal cell polarity	GO:0035088	21	0.010
carbohydrate metabolic process	GO:0005975	230	0.010
blood circulation	GO:0008015	195	0.010

Mlst8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
immune system disease	DOID:2914	0.026
disease of anatomical entity	DOID:7	0.026
hematopoietic system disease	DOID:74	0.021
nervous system disease	DOID:863	0.014
anemia	DOID:2355	0.012

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