| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.287 | |
| stem cell development | GO:0048864 | 219 | 0.259 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.220 | |
| positive regulation of intracellular estrogen receptor signaling pathway | GO:0033148 | 4 | 0.207 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.197 | |
| rna splicing | GO:0008380 | 54 | 0.196 | Human Rat |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.163 | Human Rat |
| rna processing | GO:0006396 | 105 | 0.145 | Human Rat |
| histone modification | GO:0016570 | 159 | 0.137 | |
| organelle fission | GO:0048285 | 170 | 0.109 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.108 | |
| protein alkylation | GO:0008213 | 81 | 0.106 | |
| nuclear division | GO:0000280 | 158 | 0.100 | |
| rna interference | GO:0016246 | 2 | 0.100 | |
| amine metabolic process | GO:0009308 | 45 | 0.098 | |
| spermatid development | GO:0007286 | 108 | 0.090 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.083 | |
| regulation of androgen receptor signaling pathway | GO:0060765 | 3 | 0.082 | |
| protein ubiquitination | GO:0016567 | 171 | 0.081 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.079 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.071 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.070 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.068 | |
| mrna processing | GO:0006397 | 63 | 0.066 | Human Rat |
| negative regulation of molecular function | GO:0044092 | 258 | 0.065 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.059 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.057 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.057 | |
| genitalia development | GO:0048806 | 37 | 0.056 | |
| positive regulation of toll like receptor 4 signaling pathway | GO:0034145 | 1 | 0.055 | |
| stem cell differentiation | GO:0048863 | 268 | 0.055 | |
| muscle tissue development | GO:0060537 | 308 | 0.054 | |
| histone h3 k9 dimethylation | GO:0036123 | 4 | 0.053 | |
| axonogenesis | GO:0007409 | 274 | 0.052 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.052 | |
| t cell activation | GO:0042110 | 289 | 0.052 | |
| multicellular organism growth | GO:0035264 | 161 | 0.049 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.049 | |
| regulation of transcription by chromatin organization | GO:0034401 | 0 | 0.047 | |
| regulation of protein stability | GO:0031647 | 52 | 0.046 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.046 | |
| cell division | GO:0051301 | 120 | 0.046 | |
| spermatogenesis | GO:0007283 | 284 | 0.045 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.044 | |
| appendage development | GO:0048736 | 166 | 0.044 | |
| protein methylation | GO:0006479 | 81 | 0.043 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.043 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.042 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.042 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.040 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.040 | |
| myosin filament organization | GO:0031033 | 3 | 0.040 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.040 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.039 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.039 | |
| primary neural tube formation | GO:0014020 | 95 | 0.037 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 32 | 0.037 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.037 | Human Rat |
| heterocycle catabolic process | GO:0046700 | 280 | 0.037 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.036 | |
| cation transport | GO:0006812 | 399 | 0.036 | |
| positive regulation of chromosome organization | GO:2001252 | 33 | 0.036 | |
| angiogenesis | GO:0001525 | 201 | 0.035 | |
| actin mediated cell contraction | GO:0070252 | 15 | 0.035 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.035 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.034 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.034 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.033 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.033 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.033 | |
| skeletal muscle cell differentiation | GO:0035914 | 66 | 0.032 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.032 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.032 | |
| establishment of planar polarity | GO:0001736 | 28 | 0.031 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.030 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.030 | |
| gene silencing | GO:0016458 | 38 | 0.030 | |
| spermatid differentiation | GO:0048515 | 115 | 0.030 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.029 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.029 | |
| regulation of muscle tissue development | GO:1901861 | 97 | 0.029 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.029 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.028 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.027 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.027 | |
| dna packaging | GO:0006323 | 30 | 0.027 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.027 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.027 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.026 | |
| non canonical wnt signaling pathway | GO:0035567 | 33 | 0.026 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.026 | |
| dna metabolic process | GO:0006259 | 303 | 0.026 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.025 | |
| fat cell differentiation | GO:0045444 | 160 | 0.025 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.025 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.025 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.025 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 10 | 0.025 | |
| rna splicing via transesterification reactions | GO:0000375 | 43 | 0.024 | Human Rat |
| oogenesis | GO:0048477 | 56 | 0.024 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.024 | |
| methylation | GO:0032259 | 134 | 0.024 | |
| organelle assembly | GO:0070925 | 177 | 0.024 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.023 | |
| embryonic limb morphogenesis | GO:0030326 | 126 | 0.022 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.022 | |
| regulation of ossification | GO:0030278 | 112 | 0.022 | |
| male gamete generation | GO:0048232 | 285 | 0.022 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.022 | |
| regulation of intracellular steroid hormone receptor signaling pathway | GO:0033143 | 18 | 0.022 | |
| female gamete generation | GO:0007292 | 74 | 0.021 | |
| stem cell maintenance | GO:0019827 | 130 | 0.021 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.021 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.021 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.021 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 8 | 0.020 | |
| cell adhesion | GO:0007155 | 329 | 0.020 | |
| organelle localization | GO:0051640 | 179 | 0.020 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.020 | |
| striated muscle cell proliferation | GO:0014855 | 39 | 0.020 | |
| limb morphogenesis | GO:0035108 | 149 | 0.020 | |
| regulation of cell size | GO:0008361 | 72 | 0.020 | |
| neural tube closure | GO:0001843 | 90 | 0.019 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.019 | |
| embryonic appendage morphogenesis | GO:0035113 | 126 | 0.019 | |
| microtubule based process | GO:0007017 | 236 | 0.019 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.019 | |
| protein acylation | GO:0043543 | 64 | 0.019 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.018 | |
| lung development | GO:0030324 | 164 | 0.018 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.018 | |
| oocyte axis specification | GO:0007309 | 2 | 0.018 | |
| circadian rhythm | GO:0007623 | 114 | 0.018 | |
| positive regulation of growth | GO:0045927 | 104 | 0.018 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.017 | |
| cell maturation | GO:0048469 | 127 | 0.017 | |
| endocytosis | GO:0006897 | 168 | 0.017 | |
| nuclear transcribed mrna catabolic process nonsense mediated decay | GO:0000184 | 1 | 0.017 | |
| mesenchyme development | GO:0060485 | 152 | 0.017 | |
| gene silencing by rna | GO:0031047 | 19 | 0.017 | |
| posttranscriptional gene silencing | GO:0016441 | 10 | 0.017 | |
| developmental maturation | GO:0021700 | 193 | 0.016 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.016 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.016 | |
| respiratory tube development | GO:0030323 | 167 | 0.016 | |
| establishment of tissue polarity | GO:0007164 | 28 | 0.016 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.016 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 29 | 0.016 | |
| regulation of response to dna damage stimulus | GO:2001020 | 34 | 0.016 | |
| mapk cascade | GO:0000165 | 281 | 0.016 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.016 | |
| glucose homeostasis | GO:0042593 | 128 | 0.016 | |
| regulation of nuclear division | GO:0051783 | 56 | 0.016 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.016 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.016 | |
| mrna metabolic process | GO:0016071 | 84 | 0.016 | Human Rat |
| ribonucleoprotein complex subunit organization | GO:0071826 | 28 | 0.015 | Human |
| cation transmembrane transport | GO:0098655 | 266 | 0.015 | |
| androgen receptor signaling pathway | GO:0030521 | 8 | 0.015 | |
| multicellular organismal aging | GO:0010259 | 24 | 0.015 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.015 | |
| rhythmic process | GO:0048511 | 174 | 0.015 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.015 | |
| regulation of histone modification | GO:0031056 | 56 | 0.015 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.015 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.014 | |
| regulation of satellite cell proliferation | GO:0014842 | 5 | 0.014 | |
| female gonad development | GO:0008585 | 71 | 0.014 | |
| fertilization | GO:0009566 | 127 | 0.014 | |
| receptor biosynthetic process | GO:0032800 | 3 | 0.014 | |
| protein catabolic process | GO:0030163 | 221 | 0.014 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 19 | 0.014 | |
| gonad development | GO:0008406 | 141 | 0.014 | |
| chromatin modification | GO:0016568 | 187 | 0.014 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.014 | |
| chromatin organization | GO:0006325 | 206 | 0.014 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.014 | |
| ncrna 3 end processing | GO:0043628 | 2 | 0.014 | |
| germ cell development | GO:0007281 | 185 | 0.013 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.013 | |
| intracellular estrogen receptor signaling pathway | GO:0030520 | 11 | 0.013 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.013 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.013 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.013 | |
| humoral immune response | GO:0006959 | 57 | 0.013 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.013 | |
| regulation of vasculature development | GO:1901342 | 88 | 0.013 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.013 | |
| morphogenesis of a polarized epithelium | GO:0001738 | 37 | 0.013 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.013 | |
| tube formation | GO:0035148 | 140 | 0.013 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.013 | |
| digestive tract development | GO:0048565 | 190 | 0.012 | |
| regulation of ion transport | GO:0043269 | 215 | 0.012 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.012 | |
| epidermis development | GO:0008544 | 187 | 0.012 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.012 | |
| ossification | GO:0001503 | 216 | 0.012 | |
| regulation of protein localization | GO:0032880 | 231 | 0.012 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.012 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.012 | |
| positive regulation of macroautophagy | GO:0016239 | 3 | 0.012 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.012 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.012 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.012 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.012 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.012 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.012 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.012 | |
| appendage morphogenesis | GO:0035107 | 149 | 0.012 | |
| actin filament organization | GO:0007015 | 113 | 0.012 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.011 | |
| chromosome segregation | GO:0007059 | 48 | 0.011 | |
| skeletal muscle organ development | GO:0060538 | 163 | 0.011 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.011 | |
| regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902175 | 9 | 0.011 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.011 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.011 | |
| oocyte construction | GO:0007308 | 2 | 0.011 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.011 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.011 | |
| maintenance of location | GO:0051235 | 89 | 0.011 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.011 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.011 | |
| embryonic skeletal system development | GO:0048706 | 120 | 0.011 | |
| positive regulation of intracellular steroid hormone receptor signaling pathway | GO:0033145 | 4 | 0.011 | |
| nuclear transcribed mrna catabolic process | GO:0000956 | 16 | 0.011 | |
| macromolecule methylation | GO:0043414 | 120 | 0.010 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.010 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.010 | |
| protein stabilization | GO:0050821 | 25 | 0.010 | |
| regulation of chromatin silencing | GO:0031935 | 2 | 0.010 | |
| neuroepithelial cell differentiation | GO:0060563 | 37 | 0.010 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.010 | |
| protein maturation | GO:0051604 | 176 | 0.010 | |
| striated muscle cell development | GO:0055002 | 125 | 0.010 | |
| response to peptide hormone | GO:0043434 | 127 | 0.010 | |
| protein localization to organelle | GO:0033365 | 185 | 0.010 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.010 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.010 | |