IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Adhfe1

alcohol dehydrogenase, iron containing, 1

(Aliases: 6330565B14Rik,AI043035,Adh8)

Ensembl: ENSMUSG00000025911
Entrez: 76187
UniProtKB: Q8R0N6

Process Predictions
Disease Predictions

Adhfe1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular amino acid metabolic process	GO:0006520	103	0.331
cellular lipid metabolic process	GO:0044255	323	0.230
lipid biosynthetic process	GO:0008610	179	0.206
oxidation reduction process	GO:0055114	342	0.191
fatty acid metabolic process	GO:0006631	121	0.163
glycerolipid metabolic process	GO:0046486	122	0.154
monocarboxylic acid metabolic process	GO:0032787	191	0.142
neutral lipid metabolic process	GO:0006638	57	0.133
cellular ketone metabolic process	GO:0042180	84	0.126
acylglycerol metabolic process	GO:0006639	55	0.107
cellular amine metabolic process	GO:0044106	44	0.100
small molecule catabolic process	GO:0044282	71	0.098
amine metabolic process	GO:0009308	45	0.094
regulation of cellular ketone metabolic process	GO:0010565	66	0.090
cofactor metabolic process	GO:0051186	80	0.085
sulfur compound metabolic process	GO:0006790	100	0.077
nucleobase containing small molecule metabolic process	GO:0055086	352	0.074
carbohydrate metabolic process	GO:0005975	230	0.067
glycerolipid biosynthetic process	GO:0045017	50	0.062
cellular amino acid catabolic process	GO:0009063	25	0.062
response to organic cyclic compound	GO:0014070	198	0.058
organic acid catabolic process	GO:0016054	51	0.058
carboxylic acid biosynthetic process	GO:0046394	86	0.054
organic acid biosynthetic process	GO:0016053	86	0.054
triglyceride biosynthetic process	GO:0019432	17	0.050
coenzyme metabolic process	GO:0006732	52	0.048
alcohol metabolic process	GO:0006066	116	0.046
regulation of cellular amino acid metabolic process	GO:0006521	5	0.046
small molecule biosynthetic process	GO:0044283	132	0.045
alpha amino acid metabolic process	GO:1901605	59	0.045
xenobiotic catabolic process	GO:0042178	1	0.044
regulation of cellular amine metabolic process	GO:0033238	20	0.043
response to organonitrogen compound	GO:0010243	246	0.043
organonitrogen compound catabolic process	GO:1901565	264	0.042
carboxylic acid catabolic process	GO:0046395	51	0.041
acylglycerol biosynthetic process	GO:0046463	18	0.039
acetate metabolic process	GO:0006083	1	0.039
alpha amino acid catabolic process	GO:1901606	18	0.038
thioester metabolic process	GO:0035383	19	0.038
regulation of lipid metabolic process	GO:0019216	118	0.037
long chain fatty acid import	GO:0044539	2	0.036
fat cell differentiation	GO:0045444	160	0.036
neutral lipid biosynthetic process	GO:0046460	18	0.036
cellular response to organonitrogen compound	GO:0071417	145	0.035
cellular modified amino acid metabolic process	GO:0006575	63	0.035
regulation of lipid biosynthetic process	GO:0046890	54	0.035
organic hydroxy compound metabolic process	GO:1901615	203	0.035
nucleotide metabolic process	GO:0009117	332	0.035
cellular carbohydrate metabolic process	GO:0044262	119	0.033
nucleoside phosphate metabolic process	GO:0006753	338	0.032
peptidyl amino acid modification	GO:0018193	336	0.030
response to acid chemical	GO:0001101	111	0.028
lipid catabolic process	GO:0016042	69	0.028
triglyceride metabolic process	GO:0006641	51	0.028
cellular biogenic amine metabolic process	GO:0006576	28	0.028
positive regulation of cellular amine metabolic process	GO:0033240	5	0.027
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.027
reactive oxygen species metabolic process	GO:0072593	84	0.026
ribonucleoside bisphosphate metabolic process	GO:0033875	9	0.026
lipid localization	GO:0010876	126	0.025
carbohydrate biosynthetic process	GO:0016051	74	0.024
anion transport	GO:0006820	177	0.024
cellular response to hormone stimulus	GO:0032870	150	0.024
regulation of hormone levels	GO:0010817	211	0.024
response to peptide	GO:1901652	136	0.024
acyl coa metabolic process	GO:0006637	19	0.023
ion transmembrane transport	GO:0034220	361	0.023
fatty acid alpha oxidation	GO:0001561	2	0.023
cellular response to lipid	GO:0071396	145	0.022
steroid metabolic process	GO:0008202	119	0.022
glutathione metabolic process	GO:0006749	16	0.022
benzene containing compound metabolic process	GO:0042537	5	0.022
regulation of fatty acid oxidation	GO:0046320	10	0.021
blood circulation	GO:0008015	195	0.021
transmembrane transport	GO:0055085	412	0.021
negative regulation of cellular protein metabolic process	GO:0032269	247	0.021
cellular chemical homeostasis	GO:0055082	215	0.021
regulation of cellular catabolic process	GO:0031329	242	0.021
organophosphate biosynthetic process	GO:0090407	122	0.020
organic anion transport	GO:0015711	137	0.020
lipid transport	GO:0006869	98	0.020
positive regulation of protein modification process	GO:0031401	299	0.020
negative regulation of phosphorus metabolic process	GO:0010563	184	0.020
negative regulation of lipid metabolic process	GO:0045833	30	0.020
cholesterol metabolic process	GO:0008203	56	0.020
maintenance of location	GO:0051235	89	0.020
heterocycle catabolic process	GO:0046700	280	0.020
organonitrogen compound biosynthetic process	GO:1901566	192	0.020
purine containing compound metabolic process	GO:0072521	311	0.020
carboxylic acid transport	GO:0046942	100	0.019
protein catabolic process	GO:0030163	221	0.019
lipid modification	GO:0030258	65	0.019
ribose phosphate metabolic process	GO:0019693	291	0.019
cellular nitrogen compound catabolic process	GO:0044270	280	0.019
generation of precursor metabolites and energy	GO:0006091	103	0.019
organic cyclic compound catabolic process	GO:1901361	295	0.019
cation homeostasis	GO:0055080	212	0.019
camera type eye development	GO:0043010	266	0.019
cellular homeostasis	GO:0019725	240	0.019
energy derivation by oxidation of organic compounds	GO:0015980	77	0.019
regulation of blood pressure	GO:0008217	93	0.019
fatty acid oxidation	GO:0019395	28	0.019
protein localization to organelle	GO:0033365	185	0.019
carbohydrate derivative biosynthetic process	GO:1901137	183	0.018
positive regulation of glycolytic process	GO:0045821	4	0.018
multicellular organismal homeostasis	GO:0048871	164	0.018
unsaturated fatty acid metabolic process	GO:0033559	31	0.018
muscle tissue development	GO:0060537	308	0.018
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.018
monosaccharide metabolic process	GO:0005996	106	0.018
purine ribonucleotide metabolic process	GO:0009150	290	0.018
monocarboxylic acid biosynthetic process	GO:0072330	61	0.018
purine ribonucleoside metabolic process	GO:0046128	241	0.018
regulation of homeostatic process	GO:0032844	182	0.017
cellular lipid catabolic process	GO:0044242	52	0.017
regulation of anatomical structure size	GO:0090066	178	0.017
response to nutrient levels	GO:0031667	109	0.017
macromolecule catabolic process	GO:0009057	281	0.017
mapk cascade	GO:0000165	281	0.017
cellular alcohol metabolic process	GO:0044107	3	0.017
ribonucleoside metabolic process	GO:0009119	245	0.016
aspartate family amino acid metabolic process	GO:0009066	10	0.016
negative regulation of cellular amine metabolic process	GO:0033239	1	0.016
anion transmembrane transport	GO:0098656	71	0.016
lipid homeostasis	GO:0055088	63	0.016
long chain fatty acid metabolic process	GO:0001676	26	0.016
cellular alcohol biosynthetic process	GO:0044108	3	0.016
spermatogenesis	GO:0007283	284	0.016
cation transmembrane transport	GO:0098655	266	0.016
negative regulation of phosphorylation	GO:0042326	166	0.016
response to peptide hormone	GO:0043434	127	0.016
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.016
regulation of chloride transport	GO:2001225	2	0.016
organic acid transport	GO:0015849	101	0.016
synaptic transmission	GO:0007268	329	0.016
regulation of organelle organization	GO:0033043	289	0.016
striated muscle tissue development	GO:0014706	293	0.016
regulation of triglyceride biosynthetic process	GO:0010866	10	0.016
fatty acid biosynthetic process	GO:0006633	41	0.015
pyrimidine containing compound catabolic process	GO:0072529	3	0.015
glycerolipid catabolic process	GO:0046503	16	0.015
response to lipopolysaccharide	GO:0032496	128	0.015
homeostasis of number of cells	GO:0048872	210	0.015
glycerophospholipid metabolic process	GO:0006650	71	0.015
negative regulation of phosphate metabolic process	GO:0045936	184	0.015
positive regulation of protein phosphorylation	GO:0001934	242	0.015
regulation of protein serine threonine kinase activity	GO:0071900	157	0.015
response to insulin	GO:0032868	100	0.015
negative regulation of cell proliferation	GO:0008285	296	0.015
nitrogen compound transport	GO:0071705	271	0.015
sulfur compound biosynthetic process	GO:0044272	37	0.015
sterol homeostasis	GO:0055092	45	0.015
acylglycerol catabolic process	GO:0046464	11	0.015
hexose metabolic process	GO:0019318	98	0.015
acetylcholine catabolic process	GO:0006581	1	0.015
glycosyl compound metabolic process	GO:1901657	246	0.015
peptide metabolic process	GO:0006518	46	0.015
fat soluble vitamin biosynthetic process	GO:0042362	4	0.014
organic hydroxy compound biosynthetic process	GO:1901617	77	0.014
response to inorganic substance	GO:0010035	96	0.014
purine nucleoside metabolic process	GO:0042278	241	0.014
ribonucleotide metabolic process	GO:0009259	291	0.014
purine nucleotide metabolic process	GO:0006163	302	0.014
cytoplasmic transport	GO:0016482	234	0.014
cellular response to cadmium ion	GO:0071276	3	0.014
inorganic cation transmembrane transport	GO:0098662	207	0.014
posttranscriptional regulation of gene expression	GO:0010608	155	0.014
regulation of transferase activity	GO:0051338	263	0.014
isoprenoid metabolic process	GO:0006720	29	0.014
circulatory system process	GO:0003013	197	0.014
response to nitrosative stress	GO:0051409	1	0.014
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.014
skin development	GO:0043588	220	0.014
nucleoside bisphosphate metabolic process	GO:0033865	9	0.014
response to extracellular stimulus	GO:0009991	127	0.014
icosanoid metabolic process	GO:0006690	33	0.014
negative regulation of protein metabolic process	GO:0051248	282	0.014
negative regulation of molecular function	GO:0044092	258	0.014
regulation of mapk cascade	GO:0043408	248	0.014
immune effector process	GO:0002252	321	0.014
regulation of cell cycle	GO:0051726	281	0.014
response to molecule of bacterial origin	GO:0002237	143	0.013
male gamete generation	GO:0048232	285	0.013
negative regulation of protein modification process	GO:0031400	163	0.013
cellular response to acid chemical	GO:0071229	68	0.013
regulation of kinase activity	GO:0043549	249	0.013
aromatic compound catabolic process	GO:0019439	286	0.013
cation transport	GO:0006812	399	0.013
dna metabolic process	GO:0006259	303	0.013
regulation of plasma lipoprotein particle levels	GO:0097006	23	0.013
cell type specific apoptotic process	GO:0097285	268	0.013
intracellular protein transport	GO:0006886	204	0.013
positive regulation of cellular ph reduction	GO:0032849	2	0.013
nucleoside metabolic process	GO:0009116	246	0.013
regulation of glucose metabolic process	GO:0010906	60	0.013
regulation of system process	GO:0044057	200	0.013
muscle cell differentiation	GO:0042692	261	0.013
fatty acid derivative metabolic process	GO:1901568	33	0.013
monosaccharide biosynthetic process	GO:0046364	44	0.013
negative regulation of intracellular signal transduction	GO:1902532	167	0.013
urogenital system development	GO:0001655	261	0.013
diacylglycerol biosynthetic process	GO:0006651	2	0.013
fatty acid catabolic process	GO:0009062	25	0.013
regulation of triglyceride metabolic process	GO:0090207	17	0.013
regulation of fat cell differentiation	GO:0045598	81	0.013
cellular response to peptide hormone stimulus	GO:0071375	92	0.012
nucleocytoplasmic transport	GO:0006913	139	0.012
cellular response to peptide	GO:1901653	92	0.012
saturated monocarboxylic acid metabolic process	GO:0032788	2	0.012
glucose metabolic process	GO:0006006	92	0.012
brown fat cell differentiation	GO:0050873	36	0.012
hormone metabolic process	GO:0042445	86	0.012
gland development	GO:0048732	330	0.012
regulation of carbohydrate metabolic process	GO:0006109	75	0.012
positive regulation of fatty acid oxidation	GO:0046321	4	0.012
metal ion homeostasis	GO:0055065	189	0.012
regulation of cell activation	GO:0050865	289	0.012
organophosphate catabolic process	GO:0046434	232	0.012
hematopoietic progenitor cell differentiation	GO:0002244	143	0.012
cell adhesion	GO:0007155	329	0.012
peptidyl tyrosine modification	GO:0018212	145	0.012
nadph regeneration	GO:0006740	2	0.012
myeloid cell differentiation	GO:0030099	233	0.012
membrane organization	GO:0061024	245	0.012
nuclear division	GO:0000280	158	0.012
skeletal system development	GO:0001501	356	0.012
ras protein signal transduction	GO:0007265	77	0.012
epidermis development	GO:0008544	187	0.012
cellular ion homeostasis	GO:0006873	165	0.012
sensory perception	GO:0007600	245	0.012
coenzyme biosynthetic process	GO:0009108	23	0.012
nuclear transport	GO:0051169	139	0.012
nitrobenzene metabolic process	GO:0018916	1	0.012
pyruvate metabolic process	GO:0006090	28	0.012
multi multicellular organism process	GO:0044706	109	0.012
vitamin d biosynthetic process	GO:0042368	3	0.012
protein targeting	GO:0006605	143	0.012
glycoprotein metabolic process	GO:0009100	116	0.012
tissue homeostasis	GO:0001894	115	0.012
reactive nitrogen species metabolic process	GO:2001057	0	0.012
dicarboxylic acid metabolic process	GO:0043648	18	0.012
positive regulation of cell development	GO:0010720	237	0.012
multicellular organismal signaling	GO:0035637	91	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.012
regulation of secretion	GO:0051046	274	0.011
negative regulation of protein phosphorylation	GO:0001933	126	0.011
apoptotic signaling pathway	GO:0097190	306	0.011
nucleoside phosphate biosynthetic process	GO:1901293	79	0.011
coenzyme a metabolic process	GO:0015936	8	0.011
renal system development	GO:0072001	225	0.011
naphthalene containing compound metabolic process	GO:0090420	1	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.011
forebrain development	GO:0030900	302	0.011
regulation of protein kinase activity	GO:0045859	232	0.011
hexose biosynthetic process	GO:0019319	39	0.011
cellular response to extracellular stimulus	GO:0031668	81	0.011
positive regulation of protein kinase activity	GO:0045860	144	0.011
rhythmic process	GO:0048511	174	0.011
organic hydroxy compound catabolic process	GO:1901616	25	0.011
blood vessel morphogenesis	GO:0048514	285	0.011
polyamine catabolic process	GO:0006598	2	0.011
positive regulation of cellular catabolic process	GO:0031331	148	0.011
regulation of membrane potential	GO:0042391	192	0.011
cellular response to organic cyclic compound	GO:0071407	87	0.011
positive regulation of transferase activity	GO:0051347	167	0.011
phospholipid metabolic process	GO:0006644	87	0.011
endocytosis	GO:0006897	168	0.011
innate immune response	GO:0045087	157	0.011
regulation of cytokine production	GO:0001817	266	0.011
cellular response to external stimulus	GO:0071496	88	0.011
response to radiation	GO:0009314	165	0.011
positive regulation of apoptotic process	GO:0043065	217	0.011
protein oligomerization	GO:0051259	67	0.011
cellular macromolecule catabolic process	GO:0044265	206	0.011
cellular response to molecule of bacterial origin	GO:0071219	83	0.011
cellular response to lipopolysaccharide	GO:0071222	77	0.011
response to oxidative stress	GO:0006979	123	0.011
organelle fission	GO:0048285	170	0.011
epithelial cell development	GO:0002064	159	0.011
regulation of apoptotic signaling pathway	GO:2001233	197	0.011
nucleoside triphosphate metabolic process	GO:0009141	230	0.011
chromatin organization	GO:0006325	206	0.011
response to steroid hormone	GO:0048545	56	0.011
organic hydroxy compound transport	GO:0015850	93	0.010
terpenoid metabolic process	GO:0006721	25	0.010
monocarboxylic acid catabolic process	GO:0072329	27	0.010
cellular amino acid biosynthetic process	GO:0008652	22	0.010
regulation of protein localization	GO:0032880	231	0.010
prostaglandin metabolic process	GO:0006693	11	0.010
cellular response to nutrient levels	GO:0031669	64	0.010
small gtpase mediated signal transduction	GO:0007264	97	0.010
nucleotide biosynthetic process	GO:0009165	78	0.010
microtubule based process	GO:0007017	236	0.010
midgut development	GO:0007494	4	0.010
glycosylation	GO:0070085	62	0.010
cellular response to cytokine stimulus	GO:0071345	189	0.010
g protein coupled receptor signaling pathway	GO:0007186	243	0.010
protein import	GO:0017038	101	0.010
response to sterol	GO:0036314	4	0.010
purine containing compound biosynthetic process	GO:0072522	70	0.010
regulation of secretion by cell	GO:1903530	249	0.010

Adhfe1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.089
inherited metabolic disorder	DOID:655	0.041
amino acid metabolic disorder	DOID:9252	0.038
disease of anatomical entity	DOID:7	0.016
nervous system disease	DOID:863	0.016
connective tissue disease	DOID:65	0.013
bone disease	DOID:0080001	0.013
musculoskeletal system disease	DOID:17	0.013
bone development disease	DOID:0080006	0.013
central nervous system disease	DOID:331	0.013

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