Mus musculus

0 known processes

Spef1

sperm flagellar 1

(Aliases: Clamp,4931426K16Rik)

Spef1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of neuron differentiationGO:00456642810.203
negative regulation of immune system processGO:00026832090.154
homeostasis of number of cellsGO:00488722100.110
transmembrane transportGO:00550854120.109
regionalizationGO:00030023370.099
lymphocyte differentiationGO:00300982420.098
cation transportGO:00068123990.089
cilium morphogenesisGO:00602711020.078
negative regulation of nervous system developmentGO:00519611560.074
embryonic organ morphogenesisGO:00485622760.074
skin developmentGO:00435882200.073
wound healingGO:00420601570.070
cilium assemblyGO:0042384810.069
divalent metal ion transportGO:00708381720.066
lateral inhibitionGO:004633110.063
dendrite developmentGO:00163581150.063
leukocyte differentiationGO:00025213420.062
spinal cord developmentGO:0021510810.057
organelle assemblyGO:00709251770.055
regulation of cell activationGO:00508652890.054
regulation of leukocyte differentiationGO:19021051590.051
t cell activationGO:00421102890.049
cellular amino acid metabolic processGO:00065201030.048
cell type specific apoptotic processGO:00972852680.048
skeletal system morphogenesisGO:00487052030.046
sensory perceptionGO:00076002450.046
multicellular organismal homeostasisGO:00488711640.045
cell adhesionGO:00071553290.044
embryonic skeletal system developmentGO:00487061200.044
ion transmembrane transportGO:00342203610.044
small gtpase mediated signal transductionGO:0007264970.043
developmental growth involved in morphogenesisGO:00605601380.040
axonogenesisGO:00074092740.038
g protein coupled receptor signaling pathwayGO:00071862430.038
regulation of cell migrationGO:00303342190.038
divalent inorganic cation transportGO:00725111780.038
regulation of cellular ketone metabolic processGO:0010565660.037
positive regulation of cell deathGO:00109422240.036
calcium ion transportGO:00068161590.036
negative regulation of cell proliferationGO:00082852960.036
positive regulation of neuron differentiationGO:00456661410.036
extracellular structure organizationGO:00430621480.035
response to organic cyclic compoundGO:00140701980.035
regulation of cell motilityGO:20001452360.035
leukocyte homeostasisGO:0001776790.034
rho protein signal transductionGO:0007266320.034
synaptic transmissionGO:00072683290.034
male gamete generationGO:00482322850.033
negative regulation of cell developmentGO:00107211690.033
response to organonitrogen compoundGO:00102432460.033
epidermis developmentGO:00085441870.032
regulation of lymphocyte activationGO:00512492400.032
protein maturationGO:00516041760.032
response to acid chemicalGO:00011011110.032
regulation of cell morphogenesis involved in differentiationGO:00107691510.032
b cell activationGO:00421131610.032
regulation of auditory receptor cell differentiationGO:004560740.032
inorganic ion transmembrane transportGO:00986602340.031
microtubule based processGO:00070172360.031
cation transmembrane transportGO:00986552660.031
protein catabolic processGO:00301632210.031
bmp signaling pathwayGO:0030509930.030
developmental maturationGO:00217001930.029
positive regulation of homeostatic processGO:0032846640.029
skeletal system developmentGO:00015013560.029
regulation of neuron projection developmentGO:00109751690.029
limb morphogenesisGO:00351081490.028
negative regulation of protein metabolic processGO:00512482820.028
spermatogenesisGO:00072832840.028
epithelial cell developmentGO:00020641590.028
negative regulation of cellular protein metabolic processGO:00322692470.028
neural tube closureGO:0001843900.028
forebrain developmentGO:00309003020.028
renal system developmentGO:00720012250.028
neuron migrationGO:00017641220.027
regulation of neural retina developmentGO:006107430.027
digestive tract developmentGO:00485651900.027
gland developmentGO:00487323300.027
central nervous system neuron differentiationGO:00219531620.027
histone modificationGO:00165701590.026
regulation of organelle organizationGO:00330432890.026
macromolecule catabolic processGO:00090572810.026
ear developmentGO:00435832000.026
cellular ketone metabolic processGO:0042180840.026
erythrocyte differentiationGO:0030218880.026
blood circulationGO:00080151950.026
connective tissue developmentGO:00614481790.026
chemotaxisGO:00069352470.026
regulation of retina development in camera type eyeGO:190286630.025
regulation of cell cycle processGO:00105641600.025
amine metabolic processGO:0009308450.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
vagus nerve developmentGO:002156430.025
cellular amine metabolic processGO:0044106440.025
regulation of cellular amino acid metabolic processGO:000652150.025
positive regulation of hydrolase activityGO:00513451480.025
adaptive immune responseGO:00022501550.024
negative regulation of neuron differentiationGO:00456651010.024
ras protein signal transductionGO:0007265770.024
regulation of homeostatic processGO:00328441820.023
hematopoietic progenitor cell differentiationGO:00022441430.023
endochondral bone morphogenesisGO:0060350500.023
limb developmentGO:00601731660.023
cytokine productionGO:00018163190.023
negative regulation of molecular functionGO:00440922580.023
tissue homeostasisGO:00018941150.023
mesodermal cell migrationGO:000807840.023
protein oligomerizationGO:0051259670.023
sequestering of metal ionGO:0051238190.022
digestive system developmentGO:00551232000.022
regulation of striated muscle cell differentiationGO:0051153810.022
negative regulation of intracellular signal transductionGO:19025321670.022
myotube differentiationGO:00149021050.022
determination of left right symmetryGO:0007368800.022
regulation of ossificationGO:00302781120.022
microtubule cytoskeleton organizationGO:00002261570.021
regulation of lymphocyte differentiationGO:00456191070.021
endocytosisGO:00068971680.021
inorganic cation transmembrane transportGO:00986622070.021
adult behaviorGO:00305341350.021
lymphocyte homeostasisGO:0002260640.021
protein processingGO:00164851630.021
positive regulation of organelle organizationGO:00106381280.021
calcium ion homeostasisGO:00550741270.021
negative regulation of cellular amino acid metabolic processGO:004576300.021
organic cyclic compound catabolic processGO:19013612950.021
cell differentiation in spinal cordGO:0021515530.020
regulation of sequence specific dna binding transcription factor activityGO:00510901060.020
circulatory system processGO:00030131970.020
regulation of cellular amine metabolic processGO:0033238200.020
dna metabolic processGO:00062593030.020
regulation of myeloid cell differentiationGO:0045637960.020
regulation of membrane potentialGO:00423911920.020
leukocyte migrationGO:00509001240.020
telencephalon developmentGO:00215371860.020
mitochondrion organizationGO:00070051340.020
nucleotide metabolic processGO:00091173320.020
positive regulation of nervous system developmentGO:00519622210.020
hair cell differentiationGO:0035315400.020
regulation of blood pressureGO:0008217930.019
bundle of his developmentGO:000316640.019
muscle cell differentiationGO:00426922610.019
regulation of myotube differentiationGO:0010830620.019
microtubule based movementGO:0007018840.019
sensory perception of mechanical stimulusGO:00509541070.019
morphogenesis of embryonic epitheliumGO:00163311590.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:200076410.019
single organism cell adhesionGO:00986021560.019
myeloid cell homeostasisGO:00022621140.019
single organismal cell cell adhesionGO:00163371310.019
cell substrate adhesionGO:00315891300.019
positive regulation of programmed cell deathGO:00430682180.019
sensory perception of soundGO:0007605970.019
regulation of defense responseGO:00313472330.019
response to inorganic substanceGO:0010035960.019
response to oxygen levelsGO:0070482620.018
respiratory gaseous exchangeGO:0007585430.018
embryonic skeletal system morphogenesisGO:0048704910.018
cellular response to acid chemicalGO:0071229680.018
regulation of bindingGO:00510981110.018
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.018
cellular response to organonitrogen compoundGO:00714171450.018
negative regulation of phosphate metabolic processGO:00459361840.018
heart morphogenesisGO:00030071780.018
actin cytoskeleton organizationGO:00300362200.018
negative regulation of cell activationGO:00508661110.018
appendage morphogenesisGO:00351071490.018
cardiocyte differentiationGO:0035051870.018
covalent chromatin modificationGO:00165691630.018
skeletal muscle organ developmentGO:00605381630.018
cell fate commitmentGO:00451652100.017
regulation of t cell activationGO:00508631700.017
regulation of secretion by cellGO:19035302490.017
sensory organ morphogenesisGO:00905962420.017
t cell differentiationGO:00302171740.017
neural retina developmentGO:0003407410.017
cell maturationGO:00484691270.017
intestinal epithelial structure maintenanceGO:006072940.017
regulation of ras protein signal transductionGO:00465781140.016
regulation of transferase activityGO:00513382630.016
positive regulation of cell developmentGO:00107202370.016
regulation of mapk cascadeGO:00434082480.016
intrinsic apoptotic signaling pathwayGO:00971931320.016
regulation of cell cycleGO:00517262810.016
carbohydrate transportGO:0008643620.016
myeloid leukocyte differentiationGO:00025731190.016
tendon cell differentiationGO:003599040.016
sequestering of calcium ionGO:0051208180.016
alpha beta t cell activationGO:0046631910.016
organonitrogen compound biosynthetic processGO:19015661920.016
regulation of protein catabolic processGO:00421761080.016
muscle tissue developmentGO:00605373080.016
positive regulation of immune effector processGO:00026991070.016
protein acylationGO:0043543640.016
cartilage developmentGO:00512161400.016
chromatin modificationGO:00165681870.016
positive regulation of secondary heart field cardioblast proliferationGO:007251340.016
neuron maturationGO:0042551290.016
mechanoreceptor differentiationGO:0042490670.016
reactive oxygen species metabolic processGO:0072593840.016
regulation of myeloid leukocyte differentiationGO:0002761580.015
positive regulation of cellular amine metabolic processGO:003324050.015
skeletal muscle cell differentiationGO:0035914660.015
forebrain generation of neuronsGO:0021872630.015
response to hypoxiaGO:0001666580.015
tumor necrosis factor superfamily cytokine productionGO:0071706510.015
positive regulation of myeloid cell differentiationGO:0045639430.015
cellular response to hormone stimulusGO:00328701500.015
protein modification by small protein conjugation or removalGO:00706472070.015
compartment pattern specificationGO:000738640.015
regulation of cellular component sizeGO:00325351210.015
compound eye developmentGO:004874910.015
regulation of calcium ion transportGO:0051924690.015
protein modification by small protein conjugationGO:00324461870.015
face developmentGO:0060324380.015
purine nucleoside triphosphate catabolic processGO:00091462030.015
nucleobase containing small molecule metabolic processGO:00550863520.015
divalent inorganic cation homeostasisGO:00725071380.015
appendage developmentGO:00487361660.015
cardiac right ventricle formationGO:000321930.015
circadian rhythmGO:00076231140.015
epithelial tube formationGO:00721751300.015
carbohydrate homeostasisGO:00335001280.015
regulation of cell projection organizationGO:00313442060.015
innate immune responseGO:00450871570.014
regulation of ion transportGO:00432692150.014
regulation of protein complex assemblyGO:0043254830.014
carbohydrate derivative biosynthetic processGO:19011371830.014
organelle fissionGO:00482851700.014
respiratory system processGO:0003016250.014
negative regulation of lymphocyte activationGO:0051250910.014
auditory receptor cell differentiationGO:0042491370.014
embryonic appendage morphogenesisGO:00351131260.014
positive regulation of protein modification processGO:00314012990.014
embryonic heart tube morphogenesisGO:0003143510.014
regulation of proteolysisGO:00301621640.014
cellular component assembly involved in morphogenesisGO:00109271390.014
bone developmentGO:00603481200.014
glossopharyngeal nerve morphogenesisGO:002161540.014
renal tubule developmentGO:0061326870.014
immune effector processGO:00022523210.014
rhythmic processGO:00485111740.014
muscle system processGO:00030121410.014
ribose phosphate metabolic processGO:00196932910.014
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.014
negative regulation of phosphorus metabolic processGO:00105631840.014
nuclear divisionGO:00002801580.014
wnt signaling pathwayGO:00160551880.013
negative regulation of cellular amine metabolic processGO:003323910.013
bone morphogenesisGO:0060349780.013
pallium developmentGO:00215431200.013
autonomic nervous system developmentGO:0048483430.013
protein alkylationGO:0008213810.013
replacement ossificationGO:0036075260.013
regulation of epidermis developmentGO:0045682330.013
b cell proliferationGO:0042100530.013
positive regulation of endopeptidase activityGO:0010950430.013
vagus nerve morphogenesisGO:002164420.013
alpha beta t cell differentiationGO:0046632690.013
aortic valve morphogenesisGO:000318040.013
regulation of cytokine productionGO:00018172660.013
positive regulation of cell activationGO:00508671580.013
regulation of neural precursor cell proliferationGO:2000177700.013
striated muscle tissue developmentGO:00147062930.013
left right pattern formationGO:0060972230.013
columnar cuboidal epithelial cell differentiationGO:0002065820.013
notch signaling pathwayGO:0007219710.013
peptide secretionGO:00027901140.013
regulation of system processGO:00440572000.013
cellular homeostasisGO:00197252400.013
leukocyte proliferationGO:00706611720.013
positive regulation of cell cycle processGO:0090068610.013
membrane depolarizationGO:0051899640.013
syncytium formationGO:0006949430.013
myeloid cell differentiationGO:00300992330.013
ossificationGO:00015032160.013
negative regulation of protein modification processGO:00314001630.013
cytoplasmic transportGO:00164822340.013
regulation of nuclear divisionGO:0051783560.013
pharynx developmentGO:006046510.013
lung developmentGO:00303241640.012
positive regulation of lymphocyte mediated immunityGO:0002708620.012
embryonic epithelial tube formationGO:00018381300.012
determination of heart left right asymmetryGO:0061371480.012
coagulationGO:0050817780.012
neuron apoptotic processGO:00514021420.012
negative regulation of neuron deathGO:1901215980.012
forebrain neuron differentiationGO:0021879520.012
posttranscriptional regulation of gene expressionGO:00106081550.012
epithelial cell morphogenesisGO:0003382410.012
multi organism behaviorGO:0051705620.012
interleukin 6 productionGO:0032635580.012
maintenance of locationGO:0051235890.012
regulation of chromosome organizationGO:0033044830.012
peripheral nervous system developmentGO:0007422530.012
regulation of t cell differentiationGO:0045580830.012
thymus developmentGO:0048538410.012
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.012
positive regulation of leukocyte mediated immunityGO:0002705700.012
macromolecule methylationGO:00434141200.012
defense response to bacteriumGO:00427421190.012
response to oxidative stressGO:00069791230.012
ribonucleoside metabolic processGO:00091192450.012
organelle localizationGO:00516401790.012
purine containing compound metabolic processGO:00725213110.012
regulation of metal ion transportGO:00109591060.012
positive regulation of apoptotic processGO:00430652170.012
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.012
mitochondrion distributionGO:004831140.012
leukocyte mediated immunityGO:00024431740.012
rna processingGO:00063961050.012
positive regulation of neuron projection developmentGO:0010976790.012
organic hydroxy compound metabolic processGO:19016152030.012
lymphocyte proliferationGO:00466511640.012
regulation of chromatin modificationGO:1903308570.012
mitral valve developmentGO:000317440.012
glomerular mesangial cell developmentGO:007214430.012
reactive oxygen species biosynthetic processGO:190340980.012
activation of immune responseGO:00022531380.012
chromatin organizationGO:00063252060.012
neural precursor cell proliferationGO:00613511210.012
cilium movementGO:0003341280.011
spermatid developmentGO:00072861080.011
cellular response to growth factor stimulusGO:00713631970.011
positive regulation of lymphocyte activationGO:00512511400.011
regulation of exit from mitosisGO:000709610.011
primary neural tube formationGO:0014020950.011
spermatid differentiationGO:00485151150.011
central nervous system neuron developmentGO:0021954670.011
gliogenesisGO:00420631410.011
positive regulation of ion transportGO:0043270650.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
aromatic compound catabolic processGO:00194392860.011
nucleoside phosphate metabolic processGO:00067533380.011
cardiac chamber morphogenesisGO:0003206930.011
regulation of cell adhesionGO:00301551540.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
mitotic cell cycleGO:00002781950.011
monocarboxylic acid metabolic processGO:00327871910.011
regulation of leukocyte proliferationGO:00706631210.011
neural tube formationGO:00018411080.011
inner ear morphogenesisGO:00424721010.011
regulation of body fluid levelsGO:00508781620.011
positive regulation of t cell activationGO:00508701010.011
regulation of actin filament based processGO:0032970990.011
organophosphate catabolic processGO:00464342320.011
regulation of vesicle mediated transportGO:00606271390.011
midgut developmentGO:000749440.011
camera type eye developmentGO:00430102660.011
positive regulation of gliogenesisGO:0014015270.011
mitochondrial transportGO:0006839360.011
extracellular matrix organizationGO:00301981470.011
nephron epithelium developmentGO:0072009920.011
respiratory tube developmentGO:00303231670.011
regulation of transmembrane transportGO:00347621280.011
positive regulation of secretionGO:00510471300.011
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122840.011
g1 s transition of mitotic cell cycleGO:0000082570.011
cellular protein complex assemblyGO:00436231160.011
membrane organizationGO:00610242450.011
segmentationGO:0035282930.011
mesenchyme developmentGO:00604851520.011
ventral spinal cord developmentGO:0021517480.011
regulation of neuron deathGO:19012141340.010
response to growth factorGO:00708481980.010
immunoglobulin productionGO:0002377730.010
purine nucleoside catabolic processGO:00061522050.010
regulation of cell divisionGO:0051302760.010
ear morphogenesisGO:00424711180.010
oxidation reduction processGO:00551143420.010
protein secretionGO:00093061110.010
artery developmentGO:0060840530.010
regulation of erythrocyte differentiationGO:0045646230.010
regulation of cysteine type endopeptidase activityGO:2000116650.010
regulation of rho protein signal transductionGO:0035023710.010
cellular nitrogen compound catabolic processGO:00442702800.010
cell proliferation involved in outflow tract morphogenesisGO:006132540.010
positive regulation of cell cycleGO:0045787920.010
regulation of kinase activityGO:00435492490.010
cellular response to amino acid stimulusGO:0071230290.010
neuron deathGO:00709971540.010
protein ubiquitinationGO:00165671710.010
glycoprotein metabolic processGO:00091001160.010

Spef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.029
cancerDOID:16200.029
organ system cancerDOID:005068600.029
musculoskeletal system diseaseDOID:1700.021
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.016
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.010