Mus musculus

12 known processes

Pyhin1

pyrin and HIN domain family, member 1

(Aliases: 4930422C14,Ifix,Ifi209,AI447904,MGC130358,MGC130359)

Pyhin1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of innate immune responseGO:0045088910.920
activation of innate immune responseGO:0002218560.919
leukocyte activation involved in immune responseGO:00023661260.869
defense response to other organismGO:00985421970.862
activation of immune responseGO:00022531380.844
cell surface pattern recognition receptor signaling pathwayGO:000275220.838
immune effector processGO:00022523210.818
immune response activating signal transductionGO:00027571160.793
positive regulation of defense responseGO:00313491240.785
immune response regulating signaling pathwayGO:00027641250.772
pattern recognition receptor signaling pathwayGO:0002221470.772
regulation of defense responseGO:00313472330.757
innate immune response activating signal transductionGO:0002758500.729
immune response regulating cell surface receptor signaling pathwayGO:0002768800.698
positive regulation of innate immune responseGO:0045089800.682
cellular response to biotic stimulusGO:0071216920.638
innate immune responseGO:00450871570.633
cytokine productionGO:00018163190.573
t cell activationGO:00421102890.571
cellular response to lipopolysaccharideGO:0071222770.526
immune response activating cell surface receptor signaling pathwayGO:0002429720.510
innate immune response activating cell surface receptor signaling pathwayGO:000222040.493
response to molecule of fungal originGO:000223840.492
response to molecule of bacterial originGO:00022371430.469
defense response to virusGO:0051607680.462
detection of other organismGO:009854380.424
regulation of interferon beta productionGO:0032648130.423
regulation of lymphocyte proliferationGO:00506701170.395
stimulatory c type lectin receptor signaling pathwayGO:000222320.373
detection of fungusGO:001604620.369
regulation of multi organism processGO:00439001110.368
reactive oxygen species metabolic processGO:0072593840.352
regulation of cytokine productionGO:00018172660.351
toll like receptor 7 signaling pathwayGO:003415440.328
cellular response to interferon alphaGO:003545740.313
Mouse
regulation of defense response to virusGO:0050688180.295
leukocyte proliferationGO:00706611720.286
symbiosis encompassing mutualism through parasitismGO:0044403830.285
reactive oxygen species biosynthetic processGO:190340980.282
positive regulation of interferon alpha productionGO:003272740.271
positive regulation of cytokine productionGO:00018191740.258
negative regulation of molecular functionGO:00440922580.254
Mouse
regulation of tumor necrosis factor productionGO:0032680490.248
cellular response to lipidGO:00713961450.247
lymphocyte proliferationGO:00466511640.243
negative regulation of immune system processGO:00026832090.240
regulation of reactive oxygen species biosynthetic processGO:190342620.236
regulation of cell activationGO:00508652890.234
interferon beta productionGO:0032608160.233
cellular response to cytokine stimulusGO:00713451890.221
antigen receptor mediated signaling pathwayGO:0050851640.215
tumor necrosis factor superfamily cytokine productionGO:0071706510.213
regulation of interferon gamma productionGO:0032649570.208
viral processGO:0016032410.206
ear developmentGO:00435832000.206
Mouse
regulation of lymphocyte activationGO:00512492400.205
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.202
negative regulation of protein metabolic processGO:00512482820.201
Mouse
tumor necrosis factor productionGO:0032640500.196
regulation of nlrp3 inflammasome complex assemblyGO:190022540.195
t cell proliferationGO:00420981200.195
t cell extravasationGO:007268340.191
mapk cascadeGO:00001652810.191
cell activation involved in immune responseGO:00022631260.191
positive regulation of interferon gamma productionGO:0032729390.182
type i interferon productionGO:0032606290.173
positive regulation of t cell receptor signaling pathwayGO:005086240.173
natural killer cell mediated cytotoxicityGO:0042267290.170
interferon gamma productionGO:0032609670.168
lipopolysaccharide mediated signaling pathwayGO:0031663250.165
negative regulation of multi organism processGO:0043901680.163
regulation of hydrolase activityGO:00513362460.163
Mouse
regulation of leukocyte proliferationGO:00706631210.154
regulation of protein complex assemblyGO:0043254830.154
myeloid cell differentiationGO:00300992330.154
positive regulation of reactive oxygen species biosynthetic processGO:190342820.151
positive regulation of immune effector processGO:00026991070.149
cellular response to molecule of bacterial originGO:0071219830.148
positive regulation of immunological synapse formationGO:200052210.147
detection of biotic stimulusGO:0009595100.147
reactive nitrogen species metabolic processGO:200105700.143
extrinsic apoptotic signaling pathwayGO:00971911260.138
regulation of natural killer cell mediated cytotoxicityGO:0042269190.135
positive regulation of lymphocyte activationGO:00512511400.134
natural killer cell activationGO:0030101440.134
regulation of reactive oxygen species metabolic processGO:2000377400.134
regulation of eosinophil degranulationGO:004330910.125
cellular response to molecule of fungal originGO:007122620.125
regulation of leukocyte mediated immunityGO:00027031040.124
cell killingGO:0001906670.123
regulation of dendritic cell chemotaxisGO:200050810.122
negative regulation of toll like receptor signaling pathwayGO:0034122140.121
regulation of natural killer cell activationGO:0032814220.116
toll like receptor signaling pathwayGO:0002224380.115
viral gene expressionGO:001908030.115
regulation of protein localizationGO:00328802310.114
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.113
small gtpase mediated signal transductionGO:0007264970.109
organophosphate catabolic processGO:00464342320.107
positive regulation of viral genome replicationGO:004507020.105
negative regulation of cytokine productionGO:0001818840.104
jnk cascadeGO:0007254720.103
myeloid leukocyte differentiationGO:00025731190.103
positive regulation of t cell extravasationGO:200040920.103
cellular response to interferon betaGO:0035458210.102
cellular nitrogen compound catabolic processGO:00442702800.101
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.101
regulation of cytokine biosynthetic processGO:0042035590.101
negative regulation of viral genome replicationGO:0045071100.100
rho protein signal transductionGO:0007266320.095
viral transcriptionGO:001908330.094
regulation of mapk cascadeGO:00434082480.093
interferon beta biosynthetic processGO:004535040.091
t cell receptor signaling pathwayGO:0050852460.090
purine containing compound catabolic processGO:00725232130.089
apoptotic signaling pathwayGO:00971903060.089
positive regulation of mapk cascadeGO:00434101700.087
nitric oxide metabolic processGO:0046209250.086
regulation of response to biotic stimulusGO:0002831380.083
regulation of antigen receptor mediated signaling pathwayGO:0050854290.082
interleukin 1 productionGO:0032612310.080
response to lipopolysaccharideGO:00324961280.080
regulation of t cell proliferationGO:0042129920.080
regulation of t cell activationGO:00508631700.079
negative regulation of protein processingGO:0010955790.079
Mouse
ras protein signal transductionGO:0007265770.079
membrane fusionGO:0061025380.079
cytokine metabolic processGO:0042107710.078
regulation of lymphocyte mediated immunityGO:0002706840.077
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.075
negative regulation of hydrolase activityGO:0051346710.075
Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.075
regulation of t cell costimulationGO:200052320.074
regulation of natural killer cell mediated immunityGO:0002715190.074
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.073
regulation of sequence specific dna binding transcription factor activityGO:00510901060.073
positive regulation of reactive oxygen species metabolic processGO:2000379110.073
cd8 positive alpha beta t cell extravasationGO:003569730.072
regulation of establishment of protein localizationGO:00702011810.072
regulation of cysteine type endopeptidase activityGO:2000116650.071
Mouse
regulation of cell killingGO:0031341400.071
negative regulation of cysteine type endopeptidase activityGO:2000117220.071
Mouse
positive regulation of osteoblast differentiationGO:0045669340.070
Mouse
glycosyl compound catabolic processGO:19016582060.068
lymphocyte mediated immunityGO:00024491390.068
membrane organizationGO:00610242450.068
detection of external biotic stimulusGO:009858190.067
cytokine mediated signaling pathwayGO:00192211150.066
lymphocyte differentiationGO:00300982420.066
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.065
Mouse
regulation of b cell activationGO:0050864810.064
sequestering of calcium ionGO:0051208180.063
production of molecular mediator of immune responseGO:00024401030.063
defense response to bacteriumGO:00427421190.063
regulation of t cell extravasationGO:200040730.062
negative regulation of proteolysisGO:0045861740.062
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.060
positive regulation of stress activated mapk cascadeGO:0032874480.060
regulation of viral transcriptionGO:004678230.059
purine ribonucleoside metabolic processGO:00461282410.059
regulation of immunological synapse formationGO:200052020.059
leukocyte mediated immunityGO:00024431740.059
positive regulation of lymphocyte mediated immunityGO:0002708620.059
cytokine biosynthetic processGO:0042089680.059
natural killer cell mediated immunityGO:0002228290.059
eosinophil activationGO:004330710.058
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.058
positive regulation by symbiont of host defense responseGO:005250910.058
alpha beta t cell activationGO:0046631910.058
heterocycle catabolic processGO:00467002800.058
endocytosisGO:00068971680.057
positive regulation of cytokine biosynthetic processGO:0042108400.057
interspecies interaction between organismsGO:0044419830.057
stress activated protein kinase signaling cascadeGO:0031098810.056
nitric oxide biosynthetic processGO:0006809250.056
myeloid dendritic cell activationGO:0001773250.056
regulation of nitric oxide biosynthetic processGO:0045428180.054
viral life cycleGO:0019058360.054
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.054
t helper 17 cell chemotaxisGO:003570510.053
sequestering of metal ionGO:0051238190.053
stress activated mapk cascadeGO:0051403800.052
positive regulation of hematopoietic stem cell migrationGO:200047310.052
negative regulation of defense responseGO:0031348770.052
regulation of interleukin 2 productionGO:0032663280.051
regulation of cell motilityGO:20001452360.051
detection of bacteriumGO:001604570.050
purine ribonucleotide catabolic processGO:00091542080.049
regulation of cytoplasmic transportGO:19036491120.048
positive regulation of secretion by cellGO:19035321140.048
positive regulation of viral entry into host cellGO:004659830.048
regulation of actin nucleationGO:005112540.048
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.047
t cell differentiationGO:00302171740.047
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.046
regulation of secretionGO:00510462740.046
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.046
nucleotide metabolic processGO:00091173320.046
microglial cell activation involved in immune responseGO:000228210.045
positive regulation of cell activationGO:00508671580.045
ribonucleoside triphosphate metabolic processGO:00091992200.044
aromatic compound catabolic processGO:00194392860.044
purine nucleoside catabolic processGO:00061522050.043
glycosyl compound metabolic processGO:19016572460.043
negative regulation of viral transcriptionGO:003289730.043
negative regulation of protein maturationGO:1903318790.043
Mouse
eosinophil mediated immunityGO:000244710.042
regulation of purine nucleotide metabolic processGO:19005421690.042
protein processingGO:00164851630.042
Mouse
positive regulation of t cell costimulationGO:200052520.041
negative regulation of endopeptidase activityGO:0010951440.041
Mouse
b cell activation involved in immune responseGO:0002312500.041
purine ribonucleoside triphosphate metabolic processGO:00092052200.040
microglial cell activationGO:000177430.040
positive regulation of interleukin 18 productionGO:003274120.040
nucleobase containing small molecule metabolic processGO:00550863520.040
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.040
positive regulation of lymphocyte proliferationGO:0050671700.039
nucleoside triphosphate metabolic processGO:00091412300.039
purine nucleoside metabolic processGO:00422782410.039
nucleoside phosphate metabolic processGO:00067533380.039
regulation of rho protein signal transductionGO:0035023710.039
adaptive immune responseGO:00022501550.039
protein modification by small protein conjugationGO:00324461870.039
purine ribonucleotide metabolic processGO:00091502900.039
leukocyte differentiationGO:00025213420.038
glial cell differentiationGO:00100011310.038
purine ribonucleoside triphosphate catabolic processGO:00092071990.038
chemokine productionGO:0032602340.038
neuronal action potentialGO:0019228540.038
carbohydrate derivative catabolic processGO:19011362310.038
multicellular organismal signalingGO:0035637910.038
cytoplasmic transportGO:00164822340.038
g protein coupled receptor signaling pathwayGO:00071862430.038
glycoprotein biosynthetic processGO:0009101890.037
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.037
positive regulation of jnk cascadeGO:0046330460.037
regulation of cell migrationGO:00303342190.036
detection of bacterial lipoproteinGO:004249410.036
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.036
positive regulation of cellular amine metabolic processGO:003324050.036
regulation of secretion by cellGO:19035302490.036
b cell activationGO:00421131610.036
muscle cell differentiationGO:00426922610.035
interleukin 6 productionGO:0032635580.035
signal transduction in absence of ligandGO:0038034550.034
negative regulation of cellular amine metabolic processGO:003323910.034
organic cyclic compound catabolic processGO:19013612950.034
calcium ion homeostasisGO:00550741270.034
regulation of hematopoietic stem cell migrationGO:200047110.034
chemokine mediated signaling pathwayGO:0070098170.033
cd8 positive alpha beta t cell proliferationGO:003574010.033
negative regulation of cellular component organizationGO:00511291940.033
regulation of ion homeostasisGO:2000021640.033
interaction with hostGO:0051701220.032
positive regulation of interferon beta biosynthetic processGO:004535930.032
regulation of ras protein signal transductionGO:00465781140.032
organonitrogen compound catabolic processGO:19015652640.032
interleukin 1 beta productionGO:0032611300.031
negative regulation of cell proliferationGO:00082852960.031
regulation of leukocyte mediated cytotoxicityGO:0001910380.031
purine nucleoside triphosphate metabolic processGO:00091442260.031
tumor necrosis factor biosynthetic processGO:0042533100.031
detection of yeastGO:000187920.031
leukocyte mediated cytotoxicityGO:0001909620.031
helper t cell chemotaxisGO:003570410.031
interleukin 12 secretionGO:007261030.030
viral genome replicationGO:0019079170.030
regulation of jnk cascadeGO:0046328620.030
regulation of defense response to virus by hostGO:005069180.030
nucleoside phosphate catabolic processGO:19012922220.030
eosinophil degranulationGO:004330810.030
ossificationGO:00015032160.030
Mouse
regulation of alpha beta t cell activationGO:0046634530.030
cell recognitionGO:0008037830.030
cell adhesionGO:00071553290.030
regulation of vesicle mediated transportGO:00606271390.030
transmission of nerve impulseGO:0019226760.030
positive regulation of multi organism processGO:0043902260.030
regulation of proteolysisGO:00301621640.030
Mouse
regulation of interferon beta biosynthetic processGO:004535740.029
nucleoside triphosphate catabolic processGO:00091432050.029
positive regulation of dendritic cell chemotaxisGO:200051010.029
response to growth factorGO:00708481980.029
immune complex clearanceGO:000243420.029
response to type i interferonGO:0034340120.029
nucleotide catabolic processGO:00091662170.029
defense response to gram positive bacteriumGO:0050830500.029
negative regulation of peptidase activityGO:0010466460.029
Mouse
hematopoietic stem cell migrationGO:003570110.029
negative regulation of interleukin 6 productionGO:0032715170.029
regulation of cellular component biogenesisGO:00440871810.029
purine containing compound metabolic processGO:00725213110.028
nucleoside catabolic processGO:00091642060.028
monocyte extravasationGO:003569620.028
regulation of homeostatic processGO:00328441820.028
regulation of stress activated mapk cascadeGO:0032872690.028
negative regulation of cellular protein metabolic processGO:00322692470.028
Mouse
i kappab kinase nf kappab signalingGO:0007249850.028
purine nucleotide metabolic processGO:00061633020.028
hematopoietic progenitor cell differentiationGO:00022441430.028
epithelial tube morphogenesisGO:00605623030.028
negative regulation of eosinophil degranulationGO:004331010.028
nucleocytoplasmic transportGO:00069131390.027
regulation of interleukin 1 beta productionGO:0032651250.027
positive regulation of production of molecular mediator of immune responseGO:0002702450.027
positive regulation of tumor necrosis factor productionGO:0032760300.027
regulation of kinase activityGO:00435492490.027
detection of molecule of bacterial originGO:003249020.027
ribonucleoside catabolic processGO:00424542060.027
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.027
actin filament polymerizationGO:0030041440.027
purine nucleotide catabolic processGO:00061952110.026
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043420.026
positive regulation of actin nucleationGO:005112730.026
negative regulation of immune effector processGO:0002698550.026
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.026
positive regulation of t cell proliferationGO:0042102520.026
positive regulation of hydrolase activityGO:00513451480.026
positive regulation of kinase activityGO:00336741550.026
cellular response to growth factor stimulusGO:00713631970.026
positive regulation of t cell activationGO:00508701010.026
negative regulation of leukocyte mediated immunityGO:0002704290.026
exocytosisGO:00068871210.026
proteolysis involved in cellular protein catabolic processGO:00516031470.026
anatomical structure homeostasisGO:00602491450.026
alpha beta t cell proliferationGO:0046633210.025
myd88 dependent toll like receptor signaling pathwayGO:000275570.025
second messenger mediated signalingGO:0019932730.025
single organismal cell cell adhesionGO:00163371310.025
b cell proliferationGO:0042100530.025
ribonucleoside triphosphate catabolic processGO:00092031990.025
actin polymerization or depolymerizationGO:0008154540.025
positive regulation of cell migrationGO:00303351090.025
positive regulation of secretionGO:00510471300.024
cytokine secretionGO:0050663720.024
positive regulation of monocyte extravasationGO:200043910.024
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.024
positive regulation of rac gtpase activityGO:0032855140.024
negative regulation of intracellular signal transductionGO:19025321670.023
germ cell developmentGO:00072811850.023
cd4 positive alpha beta t cell differentiationGO:0043367410.023
regulation of type 2 immune responseGO:0002828180.023
purine ribonucleoside catabolic processGO:00461302050.023
ribonucleotide metabolic processGO:00092592910.023
vesicle organizationGO:0016050600.023
positive regulation of nucleotide catabolic processGO:0030813880.023
regulation of protein processingGO:0070613960.023
Mouse
peptidyl amino acid modificationGO:00181933360.023
regulation of interleukin 12 productionGO:0032655300.023
ensheathment of neuronsGO:0007272760.023
cellular divalent inorganic cation homeostasisGO:00725031270.023
regulation of monocyte extravasationGO:200043720.022
interleukin 18 productionGO:003262140.022
positive regulation of platelet activationGO:001057250.022
ameboidal type cell migrationGO:00016671280.022
carbohydrate derivative biosynthetic processGO:19011371830.022
regulation of production of molecular mediator of immune responseGO:0002700650.022
positive regulation of apoptotic processGO:00430652170.022
regulation of apoptotic signaling pathwayGO:20012331970.022
morphogenesis of a branching structureGO:00017632030.022
negative regulation of cell developmentGO:00107211690.022
positive regulation of natural killer cell mediated immunityGO:0002717160.022
eosinophil activation involved in immune responseGO:000227810.022
protein kinase b signalingGO:0043491740.022
cation transportGO:00068123990.022
positive regulation of leukocyte proliferationGO:0070665730.022
cellular amine metabolic processGO:0044106440.022
positive regulation of nitric oxide biosynthetic processGO:0045429140.021
protein maturationGO:00516041760.021
Mouse
regulation of gtp catabolic processGO:00331241130.021
regulation of cellular ketone metabolic processGO:0010565660.021
forebrain developmentGO:00309003020.021
regulation of cell cycle processGO:00105641600.021
regulation of vesicle fusionGO:003133860.021
regulation of cellular catabolic processGO:00313292420.021
plasma membrane organizationGO:0007009900.021
regulation of organelle organizationGO:00330432890.021
negative regulation of reactive oxygen species metabolic processGO:2000378100.021
stem cell differentiationGO:00488632680.021
regulation of ossificationGO:00302781120.021
Mouse
negative regulation of synapse assemblyGO:005196430.021
protein localization to membraneGO:00726571080.021
negative regulation of cellular amino acid metabolic processGO:004576300.021
positive regulation of cellular catabolic processGO:00313311480.021
t cell differentiation involved in immune responseGO:0002292300.020
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.020
positive regulation of regulatory t cell differentiationGO:004559140.020
intracellular protein transportGO:00068862040.020
platelet morphogenesisGO:0036344130.020
regulation of nucleoside metabolic processGO:00091181300.020
defense response to protozoanGO:0042832250.020
regulation of nucleotide catabolic processGO:00308111220.020
negative regulation of nervous system developmentGO:00519611560.020
regulation of peptidase activityGO:0052547960.020
Mouse
negative regulation of phosphate metabolic processGO:00459361840.020
positive regulation of type i interferon mediated signaling pathwayGO:006034040.020
regulation of protein maturationGO:1903317960.020
Mouse
positive regulation of cell killingGO:0031343330.020
protein secretionGO:00093061110.019
positive regulation of leukocyte mediated immunityGO:0002705700.019
positive regulation of purine nucleotide metabolic processGO:19005441140.019
negative regulation of viral entry into host cellGO:0046597100.019
wound healingGO:00420601570.019
regulation of toll like receptor signaling pathwayGO:0034121200.019
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.019
carbohydrate metabolic processGO:00059752300.019
cellular protein complex assemblyGO:00436231160.019
negative regulation of macrophage apoptotic processGO:200011030.019
myeloid leukocyte activationGO:0002274830.019
immune complex clearance by monocytes and macrophagesGO:000243620.019
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.019
cd4 positive alpha beta t cell activationGO:0035710450.019
negative regulation of cell cycleGO:00457861230.019
phagocytosisGO:0006909660.018
positive t cell selectionGO:0043368230.018
positive regulation of chemokine productionGO:0032722220.018
positive regulation of ras gtpase activityGO:0032320650.018
regulation of bindingGO:00510981110.018
peptide transportGO:00158331330.018
guanosine containing compound catabolic processGO:19010691440.018
regulation of rho gtpase activityGO:0032319580.018
cellular amino acid metabolic processGO:00065201030.018
negative regulation of phosphorus metabolic processGO:00105631840.018
positive regulation of alpha beta t cell activationGO:0046635390.018
neuron migrationGO:00017641220.017
negative regulation of bindingGO:0051100390.017
regulation of protein secretionGO:0050708820.017
maintenance of locationGO:0051235890.017
modification by symbiont of host morphology or physiologyGO:004400340.017
protein localization to organelleGO:00333651850.017
negative regulation of homeostatic processGO:0032845710.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
neutrophil migrationGO:1990266370.017
positive regulation of gtpase activityGO:0043547850.017
nuclear importGO:0051170950.017
erk1 and erk2 cascadeGO:0070371770.017
organelle fusionGO:0048284280.017
regulation of interleukin 1 productionGO:0032652260.017
regulation of interleukin 6 productionGO:0032675550.017
detection of chemical stimulus involved in sensory perception of smellGO:005091140.017
regulation of actin filament polymerizationGO:0030833380.017
negative regulation of viral processGO:0048525230.017
response to hyperoxiaGO:005509320.017
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.016
interleukin 2 productionGO:0032623330.016
positive regulation of interleukin 12 productionGO:0032735210.016
microglia developmentGO:001400520.016
divalent metal ion transportGO:00708381720.016
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.016
posttranscriptional regulation of gene expressionGO:00106081550.016
myeloid cell homeostasisGO:00022621140.016
positive regulation of protein secretionGO:0050714520.016
antimicrobial peptide biosynthetic processGO:000277720.016
endomembrane system organizationGO:00102561470.016
positive regulation of apoptotic signaling pathwayGO:2001235950.016
modulation by organism of defense response of other organism involved in symbiotic interactionGO:005225510.016
natural killer cell proliferationGO:000178730.016
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.016
response to defense related host nitric oxide productionGO:005256520.016
regulation of cell cycleGO:00517262810.016
regulation of exocytosisGO:0017157610.016
ribonucleotide catabolic processGO:00092612080.016
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.016
homeostasis of number of cellsGO:00488722100.016
cellular ketone metabolic processGO:0042180840.016
response to interferon gammaGO:0034341340.016
t cell activation involved in immune responseGO:0002286430.016
positive regulation of leukocyte differentiationGO:1902107860.016
positive regulation of monocyte chemotaxisGO:009002620.016
cellular protein catabolic processGO:00442571550.015
cerebral cortex developmentGO:0021987860.015
protein targetingGO:00066051430.015
cellular response to organic cyclic compoundGO:0071407870.015
cellular homeostasisGO:00197252400.015
oligodendrocyte differentiationGO:0048709530.015
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697820.015
regulation of antimicrobial humoral responseGO:000275930.015
ribose phosphate metabolic processGO:00196932910.015
response to host immune responseGO:005257230.015
positive regulation of ossificationGO:0045778470.015
Mouse
positive regulation of endocytosisGO:0045807420.015
regulation of nucleotide metabolic processGO:00061401690.015
negative regulation of innate immune responseGO:0045824170.015
negative regulation of lymphocyte activationGO:0051250910.015
positive regulation of purine nucleotide catabolic processGO:0033123880.015
blood vessel morphogenesisGO:00485142850.015
regulation of myeloid cell differentiationGO:0045637960.015
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.015
protein polyubiquitinationGO:0000209330.015
amine metabolic processGO:0009308450.015
positive regulation of nf kappab transcription factor activityGO:0051092300.015
regulation of type i interferon productionGO:0032479220.015
mitotic cell cycle processGO:19030471590.015
positive regulation of response to woundingGO:1903036660.014
positive regulation of interferon alpha biosynthetic processGO:004535610.014
nitrogen compound transportGO:00717052710.014
regulation of cytokine production involved in immune responseGO:0002718260.014

Pyhin1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org