IMP: Integrative Multi-species Prediction

Mus musculus

116 known processes

Msx3

homeobox, msh-like 3

(Aliases: AI323377)

Entrez: 17703
Ensembl: ENSMUSG00000025469
UniProtKB: B2RPS3
UniProtKB: P70354
UniProtKB: G3X9C7

Process Predictions
Disease Predictions

Msx3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
central nervous system neuron differentiation	GO:0021953	162	0.786
leukocyte differentiation	GO:0002521	342	0.736
spinal cord development	GO:0021510	81	0.690
cerebral cortex development	GO:0021987	86	0.669
forebrain development	GO:0030900	302	0.639	Mouse
regionalization	GO:0003002	337	0.603	Zebrafish Mouse Fly
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.588
b cell activation	GO:0042113	161	0.550
muscle cell differentiation	GO:0042692	261	0.548	Mouse
cellular amine metabolic process	GO:0044106	44	0.534
axonogenesis	GO:0007409	274	0.533
regulation of neuron differentiation	GO:0045664	281	0.531
skeletal system development	GO:0001501	356	0.508	Zebrafish Mouse
ventral spinal cord development	GO:0021517	48	0.492
germ cell development	GO:0007281	185	0.486	Worm
cellular amino acid metabolic process	GO:0006520	103	0.475
cell differentiation in spinal cord	GO:0021515	53	0.469
organ growth	GO:0035265	117	0.468	Mouse
skeletal system morphogenesis	GO:0048705	203	0.457	Zebrafish Mouse
t cell differentiation	GO:0030217	174	0.451
muscle tissue development	GO:0060537	308	0.445
regulation of cellular amino acid metabolic process	GO:0006521	5	0.442
striated muscle tissue development	GO:0014706	293	0.436
regulation of neuron projection development	GO:0010975	169	0.435
lymphocyte differentiation	GO:0030098	242	0.434
positive regulation of protein modification process	GO:0031401	299	0.433
regulation of neuron death	GO:1901214	134	0.427	Zebrafish
cytokine production	GO:0001816	319	0.420
regulation of cellular ketone metabolic process	GO:0010565	66	0.420
limb morphogenesis	GO:0035108	149	0.401	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.391	Zebrafish Mouse
sensory organ morphogenesis	GO:0090596	242	0.389	Zebrafish Mouse
myeloid cell differentiation	GO:0030099	233	0.387
stem cell development	GO:0048864	219	0.380	Mouse
urogenital system development	GO:0001655	261	0.365
forebrain generation of neurons	GO:0021872	63	0.360
forebrain neuron differentiation	GO:0021879	52	0.350
limbic system development	GO:0021761	72	0.348
pallium development	GO:0021543	120	0.341
regulation of secretion	GO:0051046	274	0.340
regulation of gliogenesis	GO:0014013	50	0.338
locomotory behavior	GO:0007626	195	0.336	Worm
positive regulation of protein phosphorylation	GO:0001934	242	0.336
developmental maturation	GO:0021700	193	0.331	Mouse
myotube differentiation	GO:0014902	105	0.331
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.323
chemotaxis	GO:0006935	247	0.313
spermatogenesis	GO:0007283	284	0.310
tube formation	GO:0035148	140	0.309
wnt signaling pathway	GO:0016055	188	0.308
stem cell differentiation	GO:0048863	268	0.305	Mouse
connective tissue development	GO:0061448	179	0.300	Mouse
forebrain cell migration	GO:0021885	58	0.299
cartilage development	GO:0051216	140	0.292	Mouse
dendrite development	GO:0016358	115	0.282
embryonic skeletal system morphogenesis	GO:0048704	91	0.280	Zebrafish
telencephalon development	GO:0021537	186	0.276
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.274
regulation of secretion by cell	GO:1903530	249	0.260
cell fate commitment	GO:0045165	210	0.253	Fly
cerebral cortex cell migration	GO:0021795	44	0.245
spinal cord motor neuron differentiation	GO:0021522	35	0.242
smoothened signaling pathway	GO:0007224	105	0.241
t cell activation	GO:0042110	289	0.240
appendage development	GO:0048736	166	0.238	Mouse Fly
gland development	GO:0048732	330	0.236	Mouse
wound healing	GO:0042060	157	0.231	Zebrafish Mouse
lymphocyte proliferation	GO:0046651	164	0.229
epithelial tube formation	GO:0072175	130	0.228
inner ear morphogenesis	GO:0042472	101	0.223	Zebrafish
regulation of cell activation	GO:0050865	289	0.222
peptidyl tyrosine phosphorylation	GO:0018108	143	0.222
ear development	GO:0043583	200	0.221	Zebrafish Mouse
epithelial tube morphogenesis	GO:0060562	303	0.220	Mouse
kidney epithelium development	GO:0072073	121	0.219
mesenchymal cell differentiation	GO:0048762	107	0.219	Mouse
camera type eye development	GO:0043010	266	0.216
regulation of adaptive immune response	GO:0002819	90	0.216
cell type specific apoptotic process	GO:0097285	268	0.212	Zebrafish Mouse
cell fate specification	GO:0001708	72	0.208	Fly
ear morphogenesis	GO:0042471	118	0.207	Zebrafish Mouse
bmp signaling pathway	GO:0030509	93	0.205	Mouse
morphogenesis of embryonic epithelium	GO:0016331	159	0.203
regulation of lymphocyte activation	GO:0051249	240	0.202
positive regulation of cellular amine metabolic process	GO:0033240	5	0.194
neuron apoptotic process	GO:0051402	142	0.193	Zebrafish
amine metabolic process	GO:0009308	45	0.193
hair cycle	GO:0042633	90	0.188	Mouse
outflow tract morphogenesis	GO:0003151	53	0.187	Mouse
cell growth	GO:0016049	130	0.185
positive regulation of apoptotic process	GO:0043065	217	0.185	Mouse
pituitary gland development	GO:0021983	38	0.184
skeletal muscle organ development	GO:0060538	163	0.182
regulation of muscle tissue development	GO:1901861	97	0.180
multicellular organismal signaling	GO:0035637	91	0.176
peptidyl tyrosine modification	GO:0018212	145	0.174
blood vessel morphogenesis	GO:0048514	285	0.173
somatotropin secreting cell differentiation	GO:0060126	4	0.173
kidney development	GO:0001822	213	0.170
positive regulation of nervous system development	GO:0051962	221	0.166
renal tubule development	GO:0061326	87	0.165
neuron migration	GO:0001764	122	0.163
neuron fate specification	GO:0048665	30	0.163
regulation of neuron apoptotic process	GO:0043523	122	0.162	Zebrafish
astrocyte differentiation	GO:0048708	43	0.162
positive regulation of lymphocyte activation	GO:0051251	140	0.159
regulation of organ growth	GO:0046620	61	0.158
neuron projection guidance	GO:0097485	141	0.158
syncytium formation by plasma membrane fusion	GO:0000768	42	0.157
blastocyst development	GO:0001824	80	0.154
g protein coupled receptor signaling pathway	GO:0007186	243	0.154
regulation of cytokine production	GO:0001817	266	0.152
skeletal muscle cell differentiation	GO:0035914	66	0.151
negative regulation of cell development	GO:0010721	169	0.151
cell recognition	GO:0008037	83	0.150
muscle fiber development	GO:0048747	76	0.147
regulation of transferase activity	GO:0051338	263	0.146
positive regulation of cytokine production	GO:0001819	174	0.145
membrane organization	GO:0061024	245	0.145
kidney morphogenesis	GO:0060993	83	0.144
neural tube development	GO:0021915	160	0.143
embryonic skeletal system development	GO:0048706	120	0.142	Zebrafish
neurotransmitter secretion	GO:0007269	62	0.141
anatomical structure maturation	GO:0071695	49	0.141	Mouse
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.140
olfactory bulb development	GO:0021772	30	0.136
ossification	GO:0001503	216	0.136	Mouse
embryonic epithelial tube formation	GO:0001838	130	0.134
immune effector process	GO:0002252	321	0.134
syncytium formation	GO:0006949	43	0.133
cell activation involved in immune response	GO:0002263	126	0.133
positive regulation of cell death	GO:0010942	224	0.123	Mouse
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.123	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.122
muscle cell proliferation	GO:0033002	52	0.121
negative regulation of neuron apoptotic process	GO:0043524	92	0.121
regulation of cellular amine metabolic process	GO:0033238	20	0.120
negative regulation of nervous system development	GO:0051961	156	0.120
positive regulation of lymphocyte mediated immunity	GO:0002708	62	0.120
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.120
digestive tract development	GO:0048565	190	0.119
ventral spinal cord interneuron differentiation	GO:0021514	16	0.119
retina development in camera type eye	GO:0060041	119	0.119
regulation of homeostatic process	GO:0032844	182	0.119
determination of left right symmetry	GO:0007368	80	0.115
b cell proliferation	GO:0042100	53	0.115
telencephalon cell migration	GO:0022029	55	0.112
diencephalon development	GO:0021536	63	0.112
adaptive immune response	GO:0002250	155	0.109
positive regulation of lymphocyte proliferation	GO:0050671	70	0.109
regulation of response to wounding	GO:1903034	189	0.109
renal tubule morphogenesis	GO:0061333	72	0.108
leukocyte migration	GO:0050900	124	0.107
regulation of kinase activity	GO:0043549	249	0.107
forebrain neuron development	GO:0021884	30	0.107
endocrine system development	GO:0035270	98	0.107
synapse organization	GO:0050808	125	0.105
neural tube patterning	GO:0021532	43	0.104
regulation of interferon gamma production	GO:0032649	57	0.104
regulation of leukocyte proliferation	GO:0070663	121	0.102
hindbrain morphogenesis	GO:0021575	46	0.102
astrocyte fate commitment	GO:0060018	4	0.101
renal vesicle induction	GO:0072034	3	0.101
circulatory system process	GO:0003013	197	0.100
alpha beta t cell activation	GO:0046631	91	0.099
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.099
insulin secretion	GO:0030073	89	0.098
regulation of cardioblast differentiation	GO:0051890	3	0.098
nephron development	GO:0072006	109	0.097
canonical wnt signaling pathway	GO:0060070	130	0.097
negative regulation of neuron differentiation	GO:0045665	101	0.097
branching morphogenesis of an epithelial tube	GO:0048754	159	0.097	Mouse
sensory perception	GO:0007600	245	0.097
appendage morphogenesis	GO:0035107	149	0.096	Mouse Fly
cell maturation	GO:0048469	127	0.095
limb development	GO:0060173	166	0.095	Mouse
leukocyte activation involved in immune response	GO:0002366	126	0.095
male gamete generation	GO:0048232	285	0.095
hair follicle development	GO:0001942	85	0.095	Mouse
positive regulation of glial cell differentiation	GO:0045687	21	0.094
spinal cord dorsal ventral patterning	GO:0021513	23	0.094
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.094	Mouse
oligodendrocyte differentiation	GO:0048709	53	0.094
leukocyte proliferation	GO:0070661	172	0.094
positive regulation of leukocyte proliferation	GO:0070665	73	0.094
endocrine pancreas development	GO:0031018	29	0.093
positive regulation of adaptive immune response	GO:0002821	61	0.092
cytoplasmic transport	GO:0016482	234	0.092
positive regulation of cell development	GO:0010720	237	0.091
t cell activation involved in immune response	GO:0002286	43	0.090
digestive system development	GO:0055123	200	0.090
nerve development	GO:0021675	67	0.089
defense response to bacterium	GO:0042742	119	0.089
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.089
hypophysis morphogenesis	GO:0048850	3	0.088
paramesonephric duct development	GO:0061205	3	0.088
chondrocyte differentiation	GO:0002062	72	0.088	Mouse
motor neuron axon guidance	GO:0008045	26	0.088
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.087
central nervous system neuron development	GO:0021954	67	0.087
mesenchymal cell development	GO:0014031	93	0.086	Mouse
organic hydroxy compound metabolic process	GO:1901615	203	0.086
embryonic appendage morphogenesis	GO:0035113	126	0.086	Mouse
ureteric bud morphogenesis	GO:0060675	62	0.086
myoblast differentiation	GO:0045445	52	0.086
regulation of cellular response to stress	GO:0080135	159	0.085
myotube cell development	GO:0014904	60	0.084
positive regulation of cell activation	GO:0050867	158	0.084
endomembrane system organization	GO:0010256	147	0.083
single fertilization	GO:0007338	82	0.083
cardiac muscle cell proliferation	GO:0060038	31	0.083
neuronal action potential	GO:0019228	54	0.082
negative regulation of cell proliferation	GO:0008285	296	0.082	Mouse
angiogenesis	GO:0001525	201	0.082
cell differentiation in hindbrain	GO:0021533	24	0.082
regulation of glial cell differentiation	GO:0045685	41	0.081
regulation of cell migration	GO:0030334	219	0.081
adult locomotory behavior	GO:0008344	91	0.081
regulation of asymmetric cell division	GO:0009786	4	0.081
regulation of apoptotic signaling pathway	GO:2001233	197	0.081
muscle tissue morphogenesis	GO:0060415	53	0.081
regulation of membrane potential	GO:0042391	192	0.079
stem cell maintenance	GO:0019827	130	0.079
placenta development	GO:0001890	140	0.079
negative regulation of neuron death	GO:1901215	98	0.079
nephron morphogenesis	GO:0072028	69	0.079
hindbrain development	GO:0030902	128	0.079
apoptotic signaling pathway	GO:0097190	306	0.078
neural precursor cell proliferation	GO:0061351	121	0.077
positive regulation of kinase activity	GO:0033674	155	0.077
detection of stimulus	GO:0051606	84	0.077
cranial nerve development	GO:0021545	41	0.076
interleukin 1 production	GO:0032612	31	0.076
adult behavior	GO:0030534	135	0.076
regulation of body fluid levels	GO:0050878	162	0.075
peptidyl amino acid modification	GO:0018193	336	0.075
positive regulation of neuron differentiation	GO:0045666	141	0.075
axon guidance	GO:0007411	141	0.075
neuron death	GO:0070997	154	0.074	Zebrafish
regulation of cell division	GO:0051302	76	0.074	Mouse
gliogenesis	GO:0042063	141	0.074	Fly
palate development	GO:0060021	76	0.073	Mouse
cytokine biosynthetic process	GO:0042089	68	0.072
gonad development	GO:0008406	141	0.072
brain morphogenesis	GO:0048854	32	0.072
renal system development	GO:0072001	225	0.071
response to organonitrogen compound	GO:0010243	246	0.071
regulation of cell cycle	GO:0051726	281	0.071	Mouse
epidermis development	GO:0008544	187	0.070	Mouse
endodermal cell fate specification	GO:0001714	4	0.070
thymus development	GO:0048538	41	0.070
muscle cell development	GO:0055001	133	0.070
peptide hormone secretion	GO:0030072	109	0.070
morphogenesis of a branching structure	GO:0001763	203	0.069	Mouse
bone development	GO:0060348	120	0.068	Mouse
cochlea morphogenesis	GO:0090103	22	0.068
sensory perception of sound	GO:0007605	97	0.067
nephron epithelium morphogenesis	GO:0072088	68	0.067
cardiac muscle tissue morphogenesis	GO:0055008	44	0.067
lens morphogenesis in camera type eye	GO:0002089	24	0.067
synaptic transmission	GO:0007268	329	0.067
positive regulation of transferase activity	GO:0051347	167	0.067
tissue remodeling	GO:0048771	102	0.066
stem cell proliferation	GO:0072089	117	0.066	Mouse
peripheral nervous system development	GO:0007422	53	0.066
compound eye development	GO:0048749	1	0.066
regulation of vesicle mediated transport	GO:0060627	139	0.066
lens development in camera type eye	GO:0002088	62	0.066
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.066
neuromuscular process controlling balance	GO:0050885	59	0.065
fertilization	GO:0009566	127	0.065
development of primary male sexual characteristics	GO:0046546	88	0.065
hippocampus development	GO:0021766	52	0.065
exocytosis	GO:0006887	121	0.065
regulation of embryonic development	GO:0045995	71	0.065
lung development	GO:0030324	164	0.065
divalent metal ion transport	GO:0070838	172	0.064
molting cycle	GO:0042303	90	0.064	Mouse
striated muscle cell proliferation	GO:0014855	39	0.064
spinal cord patterning	GO:0021511	25	0.064
mesoderm development	GO:0007498	100	0.064
regulation of ossification	GO:0030278	112	0.063	Mouse
lymphocyte activation involved in immune response	GO:0002285	93	0.063
regulation of wnt signaling pathway	GO:0030111	123	0.063
mesenchyme development	GO:0060485	152	0.063	Mouse
positive regulation of gliogenesis	GO:0014015	27	0.063
ectoderm formation	GO:0001705	3	0.062
nephron epithelium development	GO:0072009	92	0.062
reactive oxygen species metabolic process	GO:0072593	84	0.061
epithelial cell development	GO:0002064	159	0.061
ventral spinal cord interneuron specification	GO:0021521	11	0.061
negative regulation of neuron projection development	GO:0010977	50	0.061
b cell mediated immunity	GO:0019724	71	0.060
t cell proliferation	GO:0042098	120	0.060
lymphocyte mediated immunity	GO:0002449	139	0.060
cellular homeostasis	GO:0019725	240	0.059
immunoglobulin mediated immune response	GO:0016064	69	0.059
endoderm development	GO:0007492	45	0.059
cell fate determination involved in pattern specification	GO:0060582	1	0.059
embryonic limb morphogenesis	GO:0030326	126	0.059	Mouse
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.058
paraxial mesodermal cell differentiation	GO:0048342	2	0.058
embryonic eye morphogenesis	GO:0048048	29	0.058
single organism cell adhesion	GO:0098602	156	0.058
female sex differentiation	GO:0046660	84	0.058
learning	GO:0007612	98	0.058
neural tube closure	GO:0001843	90	0.058
alpha beta t cell differentiation	GO:0046632	69	0.058
prostate gland development	GO:0030850	48	0.057
embryonic camera type eye development	GO:0031076	36	0.057
epithelial cell proliferation	GO:0050673	174	0.057
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.056
calcium ion dependent exocytosis	GO:0017156	35	0.056
regulation of stem cell differentiation	GO:2000736	50	0.056
blastocyst formation	GO:0001825	33	0.056
mapk cascade	GO:0000165	281	0.056
positive regulation of growth	GO:0045927	104	0.055
developmental cell growth	GO:0048588	84	0.054
globus pallidus development	GO:0021759	2	0.054
oogenesis	GO:0048477	56	0.054	Worm
metanephric dct cell differentiation	GO:0072240	3	0.054
cerebellum development	GO:0021549	77	0.054
response to growth factor	GO:0070848	198	0.054	Mouse
skeletal muscle fiber development	GO:0048741	58	0.053
cellular response to growth factor stimulus	GO:0071363	197	0.053	Mouse
regulation of canonical wnt signaling pathway	GO:0060828	82	0.053
interleukin 6 production	GO:0032635	58	0.053
sensory perception of mechanical stimulus	GO:0050954	107	0.053
loop of henle development	GO:0072070	10	0.053
cardiac atrium morphogenesis	GO:0003209	23	0.053
negative regulation of wnt signaling pathway	GO:0030178	73	0.053
protein localization to organelle	GO:0033365	185	0.053
forebrain neuron fate commitment	GO:0021877	13	0.052
positive regulation of cell migration	GO:0030335	109	0.052
positive regulation of protein kinase activity	GO:0045860	144	0.052
central nervous system vasculogenesis	GO:0022009	3	0.052
retina morphogenesis in camera type eye	GO:0060042	45	0.052
innate immune response	GO:0045087	157	0.052
defense response to other organism	GO:0098542	197	0.052
regulation of cardiac muscle tissue growth	GO:0055021	26	0.052
regulation of protein kinase activity	GO:0045859	232	0.052
respiratory gaseous exchange	GO:0007585	43	0.052
regulation of bmp signaling pathway	GO:0030510	60	0.051	Mouse
regulation of lymphocyte mediated immunity	GO:0002706	84	0.051
embryonic placenta development	GO:0001892	98	0.051
nephric duct formation	GO:0072179	4	0.051
cochlea development	GO:0090102	35	0.051
transmission of nerve impulse	GO:0019226	76	0.051
regulation of chondrocyte differentiation	GO:0032330	33	0.051
mechanoreceptor differentiation	GO:0042490	67	0.050
positive regulation of secretion	GO:0051047	130	0.050
dorsal spinal cord development	GO:0021516	20	0.050
regulation of lymphocyte proliferation	GO:0050670	117	0.050
specification of organ identity	GO:0010092	30	0.050
cerebral cortex radially oriented cell migration	GO:0021799	31	0.050
morphogenesis of a branching epithelium	GO:0061138	193	0.049	Mouse
negative regulation of immune system process	GO:0002683	209	0.049
inner ear receptor cell differentiation	GO:0060113	61	0.049
regulation of cartilage development	GO:0061035	44	0.049
notch signaling pathway	GO:0007219	71	0.049
regulation of stem cell proliferation	GO:0072091	78	0.049
nephron tubule development	GO:0072080	84	0.049
mesonephric epithelium development	GO:0072163	94	0.049
positive regulation of immune effector process	GO:0002699	107	0.049
synapse assembly	GO:0007416	56	0.048
b cell differentiation	GO:0030183	78	0.048
mesoderm morphogenesis	GO:0048332	64	0.048
cell substrate adhesion	GO:0031589	130	0.048
regulation of exocytosis	GO:0017157	61	0.048
cerebellar cortex morphogenesis	GO:0021696	32	0.047
positive regulation of cellular catabolic process	GO:0031331	148	0.047
central nervous system projection neuron axonogenesis	GO:0021952	21	0.047
cardiac muscle tissue growth	GO:0055017	37	0.047
endodermal cell fate commitment	GO:0001711	12	0.046
myeloid leukocyte differentiation	GO:0002573	119	0.046
mesoderm formation	GO:0001707	62	0.046
neural tube formation	GO:0001841	108	0.046
cellular ketone metabolic process	GO:0042180	84	0.046
carbohydrate metabolic process	GO:0005975	230	0.046
regulation of multi organism process	GO:0043900	111	0.046
pancreatic pp cell differentiation	GO:0003312	2	0.046
retinal ganglion cell axon guidance	GO:0031290	18	0.046
establishment or maintenance of cell polarity	GO:0007163	86	0.045
cellular response to cytokine stimulus	GO:0071345	189	0.045
subpallium neuron fate commitment	GO:0060163	2	0.045
paraxial mesodermal cell fate commitment	GO:0048343	2	0.045
interferon gamma production	GO:0032609	67	0.045
regulation of osteoblast differentiation	GO:0045667	67	0.045	Mouse
regulation of b cell proliferation	GO:0030888	39	0.045
gastrulation	GO:0007369	116	0.045
spemann organizer formation	GO:0060061	2	0.044
nuclear transport	GO:0051169	139	0.044
lung cell differentiation	GO:0060479	30	0.044
regulation of cellular catabolic process	GO:0031329	242	0.044
production of molecular mediator of immune response	GO:0002440	103	0.044
regulation of leukocyte mediated immunity	GO:0002703	104	0.043
regulation of cell projection organization	GO:0031344	206	0.043
positive regulation of bmp signaling pathway	GO:0030513	23	0.043	Mouse
positive regulation of ion transport	GO:0043270	65	0.043
neuromuscular process	GO:0050905	99	0.043
female gamete generation	GO:0007292	74	0.043	Worm
regulation of b cell activation	GO:0050864	81	0.043
cerebral cortex neuron differentiation	GO:0021895	19	0.042
central nervous system neuron axonogenesis	GO:0021955	28	0.042
cardiac cell fate determination	GO:0060913	2	0.042
respiratory system development	GO:0060541	190	0.042
nitrogen compound transport	GO:0071705	271	0.042
cell fate specification involved in pattern specification	GO:0060573	11	0.042
glossopharyngeal nerve morphogenesis	GO:0021615	4	0.041
maintenance of cell number	GO:0098727	3	0.041
negative regulation of cell projection organization	GO:0031345	56	0.041
liver development	GO:0001889	66	0.041
extrinsic apoptotic signaling pathway	GO:0097191	126	0.041
circadian sleep wake cycle rem sleep	GO:0042747	1	0.041
cervix development	GO:0060067	2	0.041
positive regulation of neuron projection development	GO:0010976	79	0.041
ureteric bud development	GO:0001657	94	0.040
alpha beta t cell activation involved in immune response	GO:0002287	31	0.040
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.040
negative regulation of protein metabolic process	GO:0051248	282	0.040
cerebral cortex gabaergic interneuron differentiation	GO:0021892	9	0.040
organonitrogen compound biosynthetic process	GO:1901566	192	0.040
cardiocyte differentiation	GO:0035051	87	0.040
negative regulation of prostatic bud formation	GO:0060686	4	0.040
regulation of leukocyte differentiation	GO:1902105	159	0.039
regulation of cytokine biosynthetic process	GO:0042035	59	0.039
cation transport	GO:0006812	399	0.039
regulation of cell motility	GO:2000145	236	0.039
cardiac muscle tissue development	GO:0048738	130	0.039
acetylcholine secretion neurotransmission	GO:0014055	2	0.039
mesonephric tubule development	GO:0072164	94	0.039
intrinsic apoptotic signaling pathway	GO:0097193	132	0.039
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification	GO:0021913	4	0.039
embryonic heart tube development	GO:0035050	65	0.038
action potential	GO:0001508	78	0.038
midbrain development	GO:0030901	35	0.038	Mouse
glandular epithelial cell differentiation	GO:0002067	38	0.038
small molecule biosynthetic process	GO:0044283	132	0.038
embryonic hindlimb morphogenesis	GO:0035116	32	0.038	Mouse
interleukin 1 secretion	GO:0050701	16	0.038
peptide secretion	GO:0002790	114	0.038
glial cell development	GO:0021782	54	0.037	Fly
respiratory tube development	GO:0030323	167	0.037
ameboidal type cell migration	GO:0001667	128	0.037
prostate gland epithelium morphogenesis	GO:0060740	31	0.037
trachea cartilage morphogenesis	GO:0060535	4	0.037
macromolecule catabolic process	GO:0009057	281	0.037
cell fate commitment involved in formation of primary germ layer	GO:0060795	26	0.037
neuroepithelial cell differentiation	GO:0060563	37	0.037
cerebellum morphogenesis	GO:0021587	42	0.036
oviduct development	GO:0060066	3	0.036
male gonad development	GO:0008584	88	0.036
positive regulation of mapk cascade	GO:0043410	170	0.036
autonomic nervous system development	GO:0048483	43	0.036
negative regulation of cell fate specification	GO:0009996	4	0.036
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.036
cell adhesion	GO:0007155	329	0.036
cell fate commitment involved in pattern specification	GO:0060581	14	0.036
forebrain morphogenesis	GO:0048853	17	0.036
regulation of production of molecular mediator of immune response	GO:0002700	65	0.036
biomineral tissue development	GO:0031214	64	0.036	Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	43	0.036	Mouse
b cell activation involved in immune response	GO:0002312	50	0.035
formation of primary germ layer	GO:0001704	77	0.035
hepaticobiliary system development	GO:0061008	67	0.035
regulation of interleukin 1 alpha production	GO:0032650	4	0.035
regulation of nucleotide metabolic process	GO:0006140	169	0.035
dorsal ventral neural tube patterning	GO:0021904	28	0.035
cerebellar cortex formation	GO:0021697	22	0.035
bone morphogenesis	GO:0060349	78	0.035	Mouse
cell division	GO:0051301	120	0.035	Mouse
metanephric loop of henle development	GO:0072236	4	0.035
spinal cord oligodendrocyte cell fate specification	GO:0021530	3	0.035
interleukin 8 production	GO:0032637	4	0.034
regulation of cell cycle process	GO:0010564	160	0.034	Mouse
peptidyl serine modification	GO:0018209	83	0.034
positive regulation of nucleotide metabolic process	GO:0045981	114	0.034
neural crest cell development	GO:0014032	48	0.034
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.034
sensory perception of pain	GO:0019233	47	0.034
glial cell differentiation	GO:0010001	131	0.034	Fly
ventricular septum morphogenesis	GO:0060412	27	0.034
striated muscle cell development	GO:0055002	125	0.034
regeneration	GO:0031099	38	0.034	Zebrafish
heart morphogenesis	GO:0003007	178	0.034	Mouse
acetate ester transport	GO:1901374	2	0.034
cardiac ventricle development	GO:0003231	83	0.034
post anal tail morphogenesis	GO:0036342	23	0.034
skeletal muscle tissue regeneration	GO:0043403	20	0.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.034	Mouse
digestive tract morphogenesis	GO:0048546	147	0.034
regulation of anatomical structure size	GO:0090066	178	0.034
transforming growth factor beta2 production	GO:0032906	2	0.034
pancreatic a cell fate commitment	GO:0003326	2	0.033
pancreas development	GO:0031016	57	0.033
lung epithelial cell differentiation	GO:0060487	29	0.033

Msx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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