Mus musculus

0 known processes

Shmt1

serine hydroxymethyltransferase 1 (soluble)

(Aliases: AI385541,mshmt2,mshmt,Shmt,AI324848,C81125,mshmt1)

Shmt1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.194
Human
heterocycle catabolic processGO:00467002800.113
organic cyclic compound catabolic processGO:19013612950.107
cellular nitrogen compound catabolic processGO:00442702800.100
purine containing compound metabolic processGO:00725213110.097
Human
oxidation reduction processGO:00551143420.092
nucleotide metabolic processGO:00091173320.091
purine nucleotide metabolic processGO:00061633020.087
purine nucleoside metabolic processGO:00422782410.085
purine nucleoside triphosphate metabolic processGO:00091442260.084
serine family amino acid metabolic processGO:000906970.082
Human
organic acid biosynthetic processGO:0016053860.080
nucleoside phosphate metabolic processGO:00067533380.079
ribonucleoside metabolic processGO:00091192450.077
organonitrogen compound catabolic processGO:19015652640.076
Human
glycosyl compound metabolic processGO:19016572460.075
nucleobase containing small molecule metabolic processGO:00550863520.073
Human
cellular ketone metabolic processGO:0042180840.070
regulation of cellular amino acid metabolic processGO:000652150.069
ribose phosphate metabolic processGO:00196932910.067
regulation of cellular ketone metabolic processGO:0010565660.066
ion transmembrane transportGO:00342203610.062
nucleoside metabolic processGO:00091162460.061
amine metabolic processGO:0009308450.060
alpha amino acid biosynthetic processGO:1901607150.060
transmembrane transportGO:00550854120.059
aromatic compound catabolic processGO:00194392860.056
purine ribonucleotide metabolic processGO:00091502900.056
nucleoside triphosphate metabolic processGO:00091412300.054
organonitrogen compound biosynthetic processGO:19015661920.054
Human
l serine metabolic processGO:000656320.053
Human
carboxylic acid biosynthetic processGO:0046394860.052
alpha amino acid metabolic processGO:1901605590.051
Human
purine ribonucleoside monophosphate metabolic processGO:0009167800.046
cellular response to dna damage stimulusGO:00069742070.046
regulation of cellular amine metabolic processGO:0033238200.046
purine ribonucleoside triphosphate metabolic processGO:00092052200.045
dna metabolic processGO:00062593030.045
purine ribonucleoside metabolic processGO:00461282410.045
ribonucleoside triphosphate metabolic processGO:00091992200.044
cellular amino acid biosynthetic processGO:0008652220.044
organophosphate catabolic processGO:00464342320.042
positive regulation of cellular amine metabolic processGO:003324050.041
cellular amine metabolic processGO:0044106440.040
membrane organizationGO:00610242450.040
regulation of defense responseGO:00313472330.040
positive regulation of cellular amino acid metabolic processGO:004576430.039
purine ribonucleoside catabolic processGO:00461302050.038
apoptotic signaling pathwayGO:00971903060.038
small molecule biosynthetic processGO:00442831320.038
regulation of organelle organizationGO:00330432890.038
intrinsic apoptotic signaling pathwayGO:00971931320.037
nucleoside triphosphate catabolic processGO:00091432050.037
protein oligomerizationGO:0051259670.037
Human
spermatogenesisGO:00072832840.037
nucleoside phosphate catabolic processGO:19012922220.036
ribonucleotide metabolic processGO:00092592910.036
dna repairGO:00062811070.036
nucleoside catabolic processGO:00091642060.036
ribonucleoside catabolic processGO:00424542060.034
action potentialGO:0001508780.032
anion transportGO:00068201770.032
nucleotide catabolic processGO:00091662170.032
cytokine productionGO:00018163190.032
purine nucleoside triphosphate catabolic processGO:00091462030.032
negative regulation of cellular component organizationGO:00511291940.032
ribonucleotide catabolic processGO:00092612080.031
immune effector processGO:00022523210.031
cellular lipid metabolic processGO:00442553230.030
ribonucleoside triphosphate catabolic processGO:00092031990.029
peptidyl amino acid modificationGO:00181933360.028
cation transportGO:00068123990.028
gland developmentGO:00487323300.028
purine nucleoside catabolic processGO:00061522050.027
male gamete generationGO:00482322850.027
locomotory behaviorGO:00076261950.027
aspartate family amino acid metabolic processGO:0009066100.027
regulation of cytokine productionGO:00018172660.027
purine nucleotide catabolic processGO:00061952110.026
positive regulation of apoptotic processGO:00430652170.026
endomembrane system organizationGO:00102561470.026
organic hydroxy compound metabolic processGO:19016152030.026
regulation of apoptotic signaling pathwayGO:20012331970.026
response to organonitrogen compoundGO:00102432460.025
posttranscriptional regulation of gene expressionGO:00106081550.025
protein maturationGO:00516041760.025
cell adhesionGO:00071553290.025
negative regulation of molecular functionGO:00440922580.025
multicellular organismal signalingGO:0035637910.024
cellular response to organonitrogen compoundGO:00714171450.024
positive regulation of cell deathGO:00109422240.023
purine containing compound catabolic processGO:00725232130.023
carbohydrate derivative catabolic processGO:19011362310.023
regulation of membrane potentialGO:00423911920.023
nucleotide biosynthetic processGO:0009165780.022
carbohydrate metabolic processGO:00059752300.022
cellular carbohydrate metabolic processGO:00442621190.022
generation of precursor metabolites and energyGO:00060911030.022
organic anion transportGO:00157111370.022
regulation of ion transmembrane transportGO:00347651190.022
glycosyl compound catabolic processGO:19016582060.022
germ cell developmentGO:00072811850.022
regulation of mapk cascadeGO:00434082480.021
cellular homeostasisGO:00197252400.021
leukocyte differentiationGO:00025213420.021
negative regulation of protein metabolic processGO:00512482820.021
cellular response to lipidGO:00713961450.021
monocarboxylic acid metabolic processGO:00327871910.020
purine nucleoside biosynthetic processGO:0042451190.020
organophosphate biosynthetic processGO:00904071220.020
protein homooligomerizationGO:0051260430.020
mitochondrion organizationGO:00070051340.020
endocytosisGO:00068971680.020
regulation of innate immune responseGO:0045088910.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
regulation of cell activationGO:00508652890.020
ribonucleoside monophosphate metabolic processGO:0009161800.020
energy derivation by oxidation of organic compoundsGO:0015980770.020
cellular response to cytokine stimulusGO:00713451890.019
negative regulation of phosphorus metabolic processGO:00105631840.019
cellular macromolecule catabolic processGO:00442652060.019
histone modificationGO:00165701590.019
lipid biosynthetic processGO:00086101790.019
cytoplasmic transportGO:00164822340.018
small gtpase mediated signal transductionGO:0007264970.018
regulation of response to woundingGO:19030341890.018
regulation of lymphocyte activationGO:00512492400.018
purine ribonucleotide catabolic processGO:00091542080.018
sensory perceptionGO:00076002450.018
innate immune responseGO:00450871570.018
carboxylic acid catabolic processGO:0046395510.018
Human
nucleoside phosphate biosynthetic processGO:1901293790.018
mapk cascadeGO:00001652810.017
blastocyst developmentGO:0001824800.017
nucleoside monophosphate metabolic processGO:0009123850.017
regulation of cellular response to stressGO:00801351590.017
cellular response to lipopolysaccharideGO:0071222770.017
cellular ion homeostasisGO:00068731650.017
nitrogen compound transportGO:00717052710.017
protein processingGO:00164851630.017
cellular metal ion homeostasisGO:00068751510.017
regulation of anatomical structure sizeGO:00900661780.017
negative regulation of phosphate metabolic processGO:00459361840.017
negative regulation of cellular amine metabolic processGO:003323910.017
muscle cell differentiationGO:00426922610.017
lymphocyte differentiationGO:00300982420.017
small molecule catabolic processGO:0044282710.017
Human
chromatin organizationGO:00063252060.017
cellular response to peptide hormone stimulusGO:0071375920.017
carbohydrate derivative biosynthetic processGO:19011371830.017
regulation of secretionGO:00510462740.017
macromolecule catabolic processGO:00090572810.016
heart processGO:0003015940.016
protein targetingGO:00066051430.016
adaptive immune responseGO:00022501550.016
sulfur compound metabolic processGO:00067901000.016
regulation of ion transportGO:00432692150.016
single organism cell adhesionGO:00986021560.016
cell fate commitmentGO:00451652100.016
inorganic cation transmembrane transportGO:00986622070.016
production of molecular mediator of immune responseGO:00024401030.016
regulation of nucleoside metabolic processGO:00091181300.016
transmission of nerve impulseGO:0019226760.016
regulation of mitochondrion organizationGO:0010821270.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
mitochondrial transportGO:0006839360.016
intracellular protein transportGO:00068862040.016
cellular chemical homeostasisGO:00550822150.016
organelle assemblyGO:00709251770.016
cation transmembrane transportGO:00986552660.016
cellular protein complex assemblyGO:00436231160.016
negative regulation of immune system processGO:00026832090.015
negative regulation of phosphorylationGO:00423261660.015
ras protein signal transductionGO:0007265770.015
purine nucleoside monophosphate metabolic processGO:0009126810.015
t cell activationGO:00421102890.015
metal ion homeostasisGO:00550651890.015
response to organic cyclic compoundGO:00140701980.015
divalent metal ion transportGO:00708381720.015
cation homeostasisGO:00550802120.015
protein tetramerizationGO:0051262230.015
Human
regulation of cellular component sizeGO:00325351210.015
purine containing compound biosynthetic processGO:0072522700.015
Human
regulation of hydrolase activityGO:00513362460.015
protein localization to membraneGO:00726571080.015
positive regulation of lymphocyte activationGO:00512511400.015
inflammatory responseGO:00069542440.015
regulation of translationGO:0006417710.015
meiotic nuclear divisionGO:00071261150.015
stem cell differentiationGO:00488632680.015
homeostasis of number of cellsGO:00488722100.015
response to radiationGO:00093141650.015
negative regulation of protein modification processGO:00314001630.015
heart contractionGO:0060047930.015
carboxylic acid transportGO:00469421000.015
negative regulation of intracellular signal transductionGO:19025321670.015
multicellular organism growthGO:00352641610.015
divalent inorganic cation transportGO:00725111780.015
negative regulation of organelle organizationGO:0010639900.015
establishment of organelle localizationGO:00516561220.014
regulation of mitotic cell cycleGO:00073461260.014
vitamin transmembrane transportGO:003546140.014
reactive oxygen species metabolic processGO:0072593840.014
dna dependent dna replicationGO:0006261240.014
regulation of transferase activityGO:00513382630.014
regulation of transmembrane transportGO:00347621280.014
monosaccharide metabolic processGO:00059961060.014
negative regulation of cellular protein metabolic processGO:00322692470.014
regulation of actin filament based processGO:0032970990.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
mrna metabolic processGO:0016071840.014
establishment or maintenance of cell polarityGO:0007163860.014
regulation of cell cycleGO:00517262810.014
glucose metabolic processGO:0006006920.014
organelle fissionGO:00482851700.014
digestive system developmentGO:00551232000.014
calcium ion transportGO:00068161590.014
serine family amino acid biosynthetic processGO:000907040.014
regulation of cell migrationGO:00303342190.014
translationGO:0006412930.014
lymphocyte mediated immunityGO:00024491390.014
purine ribonucleoside biosynthetic processGO:0046129190.014
atp metabolic processGO:0046034750.014
negative regulation of cell cycleGO:00457861230.014
cellular response to hormone stimulusGO:00328701500.013
intracellular mrna localizationGO:000829840.013
cellular response to molecule of bacterial originGO:0071219830.013
positive regulation of cytokine productionGO:00018191740.013
molting cycleGO:0042303900.013
fatty acid metabolic processGO:00066311210.013
gtp metabolic processGO:00460391440.013
cofactor transportGO:005118140.013
placenta developmentGO:00018901400.013
positive regulation of defense responseGO:00313491240.013
positive regulation of t cell activationGO:00508701010.013
dna recombinationGO:0006310920.013
dna endoreduplicationGO:004202340.013
chromatin modificationGO:00165681870.013
multi multicellular organism processGO:00447061090.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.013
positive regulation of cell developmentGO:00107202370.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
regulation of mrna metabolic processGO:1903311430.013
leukocyte proliferationGO:00706611720.013
b cell activationGO:00421131610.013
organelle localizationGO:00516401790.013
actin filament based movementGO:0030048230.013
regulation of proteolysisGO:00301621640.013
activation of immune responseGO:00022531380.012
regulation of hormone levelsGO:00108172110.012
purine nucleotide biosynthetic processGO:0006164650.012
regulation of system processGO:00440572000.012
circulatory system processGO:00030131970.012
multicellular organismal homeostasisGO:00488711640.012
response to oxidative stressGO:00069791230.012
inorganic ion transmembrane transportGO:00986602340.012
protein localization to organelleGO:00333651850.012
positive regulation of programmed cell deathGO:00430682180.012
regulation of cellular catabolic processGO:00313292420.012
guanosine containing compound catabolic processGO:19010691440.012
response to lipopolysaccharideGO:00324961280.012
cellular response to biotic stimulusGO:0071216920.012
dephosphorylationGO:00163111290.012
dna catabolic process endonucleolyticGO:0000737150.012
alcohol metabolic processGO:00060661160.012
striated muscle tissue developmentGO:00147062930.012
protein importGO:00170381010.012
epithelial tube morphogenesisGO:00605623030.012
response to peptideGO:19016521360.012
synaptic transmissionGO:00072683290.012
anatomical structure homeostasisGO:00602491450.012
response to peptide hormoneGO:00434341270.012
liver developmentGO:0001889660.012
regulation of cell motilityGO:20001452360.012
muscle tissue developmentGO:00605373080.012
defecationGO:003042110.012
skin developmentGO:00435882200.012
ribonucleoside monophosphate catabolic processGO:0009158570.012
ribonucleoside biosynthetic processGO:0042455210.012
rna processingGO:00063961050.012
positive regulation of apoptotic signaling pathwayGO:2001235950.012
divalent inorganic cation homeostasisGO:00725071380.012
actin filament polymerizationGO:0030041440.012
spermatid developmentGO:00072861080.012
regulation of purine nucleotide metabolic processGO:19005421690.012
adult locomotory behaviorGO:0008344910.012
cellular response to arsenic containing substanceGO:007124340.011
neuronal action potentialGO:0019228540.011
response to nutrient levelsGO:00316671090.011
organic acid transportGO:00158491010.011
response to extracellular stimulusGO:00099911270.011
glucose homeostasisGO:00425931280.011
developmental maturationGO:00217001930.011
regulation of cell adhesionGO:00301551540.011
nucleocytoplasmic transportGO:00069131390.011
regulation of inflammatory responseGO:00507271470.011
nucleic acid phosphodiester bond hydrolysisGO:0090305490.011
immunoglobulin productionGO:0002377730.011
gonad developmentGO:00084061410.011
regulation of protein kinase activityGO:00458592320.011
fertilizationGO:00095661270.011
regulation of purine nucleotide catabolic processGO:00331211220.011
regulation of protein localizationGO:00328802310.011
dna dependent dna replication maintenance of fidelityGO:004500530.011
t cell differentiationGO:00302171740.011
regulation of cellular component biogenesisGO:00440871810.011
rho protein signal transductionGO:0007266320.011
glycosyl compound biosynthetic processGO:1901659210.011
organ growthGO:00352651170.011
negative regulation of cell proliferationGO:00082852960.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
regulation of t cell activationGO:00508631700.011
covalent chromatin modificationGO:00165691630.011
hepaticobiliary system developmentGO:0061008670.011
hexose metabolic processGO:0019318980.011
positive regulation of protein phosphorylationGO:00019342420.011
morphogenesis of a branching epitheliumGO:00611381930.011
positive regulation of hydrolase activityGO:00513451480.011
digestive tract developmentGO:00485651900.011
apoptotic mitochondrial changesGO:0008637480.011
cellular modified amino acid metabolic processGO:0006575630.011
Human
regulation of homeostatic processGO:00328441820.011
nucleoside biosynthetic processGO:0009163210.011
carbohydrate homeostasisGO:00335001280.010
respiratory tube developmentGO:00303231670.010
mitotic cell cycleGO:00002781950.010
cell type specific apoptotic processGO:00972852680.010
guanosine containing compound metabolic processGO:19010681440.010
response to molecule of bacterial originGO:00022371430.010
myosin filament assemblyGO:003103420.010
blood circulationGO:00080151950.010
adult behaviorGO:00305341350.010
respiratory system developmentGO:00605411900.010
regulation of neuron differentiationGO:00456642810.010
response to light stimulusGO:00094161350.010
dna biosynthetic processGO:0071897220.010
defense response to other organismGO:00985421970.010
response to acid chemicalGO:00011011110.010
metaphase plate congressionGO:005131020.010
regulation of establishment of protein localizationGO:00702011810.010
muscle system processGO:00030121410.010

Shmt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.034
inherited metabolic disorderDOID:65500.034
amino acid metabolic disorderDOID:925200.034
disease of anatomical entityDOID:700.016
immune system diseaseDOID:291400.016
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.014
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
musculoskeletal system diseaseDOID:1700.010