| mitochondrion organization | GO:0007005 | 134 | 0.827 | |
| mitochondrial membrane organization | GO:0007006 | 26 | 0.415 | |
| protein localization to mitochondrion | GO:0070585 | 15 | 0.401 | |
| transmembrane transport | GO:0055085 | 412 | 0.361 | |
| necroptotic process | GO:0070266 | 21 | 0.203 | |
| male gamete generation | GO:0048232 | 285 | 0.162 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.145 | |
| cellular response to arsenic containing substance | GO:0071243 | 4 | 0.145 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.137 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.127 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.116 | |
| protein transmembrane transport | GO:0071806 | 8 | 0.100 | |
| membrane organization | GO:0061024 | 245 | 0.093 | |
| regulation of mitochondrion organization | GO:0010821 | 27 | 0.089 | |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.088 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.086 | |
| oxidation reduction process | GO:0055114 | 342 | 0.083 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.079 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.075 | |
| mitochondrial transport | GO:0006839 | 36 | 0.075 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.072 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.067 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.064 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.060 | |
| endocytosis | GO:0006897 | 168 | 0.058 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.057 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.054 | |
| translation | GO:0006412 | 93 | 0.054 | |
| mitochondrial calcium ion homeostasis | GO:0051560 | 7 | 0.053 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.053 | |
| alpha amino acid biosynthetic process | GO:1901607 | 15 | 0.050 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.050 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.048 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.048 | Human |
| metal ion homeostasis | GO:0055065 | 189 | 0.046 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.044 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.044 | |
| cation transport | GO:0006812 | 399 | 0.044 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.041 | |
| cellular response to lipid | GO:0071396 | 145 | 0.040 | |
| regulation of cell migration | GO:0030334 | 219 | 0.037 | Human |
| germ cell development | GO:0007281 | 185 | 0.037 | |
| anion transport | GO:0006820 | 177 | 0.037 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.036 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.036 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.036 | |
| response to oxidative stress | GO:0006979 | 123 | 0.035 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.035 | |
| cellular homeostasis | GO:0019725 | 240 | 0.035 | |
| l serine metabolic process | GO:0006563 | 2 | 0.035 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.035 | |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.034 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.034 | Human |
| response to organonitrogen compound | GO:0010243 | 246 | 0.034 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.034 | |
| cofactor transport | GO:0051181 | 4 | 0.033 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.032 | |
| carboxylic acid catabolic process | GO:0046395 | 51 | 0.032 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.032 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.031 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.030 | |
| gonad development | GO:0008406 | 141 | 0.030 | |
| pole plasm assembly | GO:0007315 | 2 | 0.030 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.030 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.030 | |
| mitochondrial respiratory chain complex assembly | GO:0033108 | 2 | 0.030 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.030 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.029 | |
| atp metabolic process | GO:0046034 | 75 | 0.029 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.029 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.029 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.029 | |
| histone methylation | GO:0016571 | 71 | 0.029 | |
| regulation of cell activation | GO:0050865 | 289 | 0.028 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.028 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.028 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.028 | |
| regulation of defense response | GO:0031347 | 233 | 0.028 | Human |
| protein processing | GO:0016485 | 163 | 0.027 | Human |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.027 | |
| spermatogenesis | GO:0007283 | 284 | 0.027 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.027 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.027 | |
| regulation of ion transport | GO:0043269 | 215 | 0.026 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.025 | Human |
| serine family amino acid metabolic process | GO:0009069 | 7 | 0.025 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.025 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.025 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.024 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.024 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.024 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.024 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.023 | |
| defecation | GO:0030421 | 1 | 0.023 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.023 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.023 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.022 | |
| protein maturation | GO:0051604 | 176 | 0.022 | Human |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.022 | Human |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.022 | |
| locomotory behavior | GO:0007626 | 195 | 0.022 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.022 | |
| regulation of engulfment of apoptotic cell | GO:1901074 | 2 | 0.022 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.022 | |
| protein localization to membrane | GO:0072657 | 108 | 0.022 | |
| mapk cascade | GO:0000165 | 281 | 0.021 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.021 | |
| amine metabolic process | GO:0009308 | 45 | 0.021 | |
| negative regulation of mitochondrion organization | GO:0010823 | 9 | 0.021 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.021 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.021 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.021 | |
| protein localization to organelle | GO:0033365 | 185 | 0.021 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.021 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.020 | |
| dna metabolic process | GO:0006259 | 303 | 0.020 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 19 | 0.020 | |
| cellular respiration | GO:0045333 | 38 | 0.020 | |
| developmental maturation | GO:0021700 | 193 | 0.020 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.020 | |
| response to alcohol | GO:0097305 | 48 | 0.019 | |
| cytokine production involved in immune response | GO:0002367 | 34 | 0.019 | |
| regulation of feeding behavior | GO:0060259 | 3 | 0.019 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.019 | |
| cellular amino acid biosynthetic process | GO:0008652 | 22 | 0.019 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.019 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.019 | |
| pigment biosynthetic process | GO:0046148 | 26 | 0.019 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.019 | |
| branching morphogenesis of an epithelial tube | GO:0048754 | 159 | 0.018 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.018 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.018 | |
| intracellular protein transport | GO:0006886 | 204 | 0.018 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.018 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.018 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 19 | 0.018 | |
| cytokine production | GO:0001816 | 319 | 0.018 | Human |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.018 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.018 | |
| regulation of generation of precursor metabolites and energy | GO:0043467 | 38 | 0.018 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.018 | Human |
| regulation of t cell activation | GO:0050863 | 170 | 0.018 | |
| regionalization | GO:0003002 | 337 | 0.017 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.017 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.017 | |
| positive regulation of mitochondrion organization | GO:0010822 | 17 | 0.017 | |
| gland development | GO:0048732 | 330 | 0.017 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.017 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.017 | |
| cation homeostasis | GO:0055080 | 212 | 0.017 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.017 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.017 | |
| action potential | GO:0001508 | 78 | 0.016 | |
| mrna metabolic process | GO:0016071 | 84 | 0.016 | Human |
| epithelial cell proliferation | GO:0050673 | 174 | 0.016 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.016 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.016 | |
| regulation of response to dna damage stimulus | GO:2001020 | 34 | 0.016 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.016 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.015 | |
| positive regulation of leukocyte mediated immunity | GO:0002705 | 70 | 0.015 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.015 | |
| inner mitochondrial membrane organization | GO:0007007 | 5 | 0.015 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.015 | |
| cell maturation | GO:0048469 | 127 | 0.015 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.015 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.015 | |
| interferon gamma production | GO:0032609 | 67 | 0.015 | Human |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.015 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.015 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.015 | |
| mitochondrial translation | GO:0032543 | 4 | 0.014 | |
| b cell activation | GO:0042113 | 161 | 0.014 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.014 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.014 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.014 | |
| cellular amino acid catabolic process | GO:0009063 | 25 | 0.014 | |
| organelle localization | GO:0051640 | 179 | 0.014 | |
| b cell proliferation | GO:0042100 | 53 | 0.014 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.014 | |
| glucose homeostasis | GO:0042593 | 128 | 0.014 | |
| immune effector process | GO:0002252 | 321 | 0.014 | Human |
| alpha amino acid catabolic process | GO:1901606 | 18 | 0.013 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.013 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.013 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.013 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.013 | |
| mesenchymal cell development | GO:0014031 | 93 | 0.013 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.013 | |
| sensory perception | GO:0007600 | 245 | 0.013 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.013 | |
| body morphogenesis | GO:0010171 | 45 | 0.013 | |
| regulation of interferon gamma production | GO:0032649 | 57 | 0.013 | Human |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.013 | |
| sodium ion transport | GO:0006814 | 73 | 0.013 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.013 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.013 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.013 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.013 | |
| purine nucleotide biosynthetic process | GO:0006164 | 65 | 0.013 | |
| oogenesis | GO:0048477 | 56 | 0.012 | |
| regulation of leukocyte apoptotic process | GO:2000106 | 56 | 0.012 | |
| maternal process involved in female pregnancy | GO:0060135 | 32 | 0.012 | |
| female gamete generation | GO:0007292 | 74 | 0.012 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.012 | |
| trna aminoacylation for protein translation | GO:0006418 | 1 | 0.012 | |
| t cell activation | GO:0042110 | 289 | 0.012 | |
| vesicle localization | GO:0051648 | 86 | 0.012 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.012 | Human |
| rhythmic process | GO:0048511 | 174 | 0.012 | |
| ribose phosphate biosynthetic process | GO:0046390 | 59 | 0.012 | |
| programmed necrotic cell death | GO:0097300 | 28 | 0.012 | |
| regulation of mitochondrial membrane permeability | GO:0046902 | 17 | 0.012 | |
| protein targeting | GO:0006605 | 143 | 0.012 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.012 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.012 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.012 | |
| leukocyte apoptotic process | GO:0071887 | 71 | 0.012 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.011 | Human |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.011 | |
| adaptive immune response | GO:0002250 | 155 | 0.011 | |
| somatic diversification of immune receptors via germline recombination within a single locus | GO:0002562 | 51 | 0.011 | |
| activation of innate immune response | GO:0002218 | 56 | 0.011 | Human |
| cytochrome complex assembly | GO:0017004 | 3 | 0.011 | |
| oocyte development | GO:0048599 | 33 | 0.011 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.011 | |
| oocyte axis specification | GO:0007309 | 2 | 0.011 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.011 | |
| regulation of sodium ion transport | GO:0002028 | 29 | 0.011 | |
| placenta development | GO:0001890 | 140 | 0.011 | |
| regulation of response to biotic stimulus | GO:0002831 | 38 | 0.011 | Human |
| wound healing | GO:0042060 | 157 | 0.011 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.011 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.011 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.011 | |
| response to acid chemical | GO:0001101 | 111 | 0.011 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 59 | 0.011 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.011 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.011 | |
| small molecule catabolic process | GO:0044282 | 71 | 0.011 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.011 | |
| response to unfolded protein | GO:0006986 | 21 | 0.010 | |
| mesenchyme development | GO:0060485 | 152 | 0.010 | |
| oxidative phosphorylation | GO:0006119 | 14 | 0.010 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.010 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.010 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.010 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.010 | |
| synaptic transmission | GO:0007268 | 329 | 0.010 | |
| oocyte construction | GO:0007308 | 2 | 0.010 | |
| microtubule based process | GO:0007017 | 236 | 0.010 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 29 | 0.010 | |
| response to nutrient levels | GO:0031667 | 109 | 0.010 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.010 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.010 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.010 | |
| positive regulation of interferon alpha production | GO:0032727 | 4 | 0.010 | |
