Mus musculus

0 known processes

Adam21

a disintegrin and metallopeptidase domain 21

(Aliases: Adam31)

Adam21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238200.205
regulation of protein kinase activityGO:00458592320.179
Mouse
cellular amine metabolic processGO:0044106440.121
positive regulation of protein phosphorylationGO:00019342420.089
Mouse
regulation of transferase activityGO:00513382630.085
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.083
regulation of lymphocyte activationGO:00512492400.072
Mouse
regulation of cellular ketone metabolic processGO:0010565660.071
regulation of protein serine threonine kinase activityGO:00719001570.071
Mouse
spermatogenesisGO:00072832840.071
amine metabolic processGO:0009308450.065
mapk cascadeGO:00001652810.064
Mouse
negative regulation of molecular functionGO:00440922580.064
nucleotide metabolic processGO:00091173320.061
regulation of cellular amino acid metabolic processGO:000652150.060
small gtpase mediated signal transductionGO:0007264970.054
positive regulation of protein modification processGO:00314012990.052
Mouse
cellular ketone metabolic processGO:0042180840.052
organic cyclic compound catabolic processGO:19013612950.051
organophosphate catabolic processGO:00464342320.050
protein maturationGO:00516041760.050
sensory perceptionGO:00076002450.047
male gamete generationGO:00482322850.047
regulation of cytokine productionGO:00018172660.046
Mouse
ribonucleotide metabolic processGO:00092592910.044
muscle tissue developmentGO:00605373080.043
regulation of eosinophil migrationGO:200041620.041
Mouse
regulation of protein localizationGO:00328802310.040
positive regulation of protein kinase activityGO:00458601440.040
Mouse
regulation of defense responseGO:00313472330.040
Mouse
inflammatory responseGO:00069542440.039
Mouse
regulation of cell activationGO:00508652890.039
Mouse
ribonucleotide catabolic processGO:00092612080.039
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.038
regulation of angiogenesisGO:0045765810.037
nucleobase containing small molecule metabolic processGO:00550863520.037
purine containing compound catabolic processGO:00725232130.037
regulation of neuron differentiationGO:00456642810.037
regulation of establishment of protein localizationGO:00702011810.037
positive regulation of thymocyte migrationGO:200041220.037
Mouse
regulation of cell projection organizationGO:00313442060.036
purine ribonucleotide metabolic processGO:00091502900.036
regulation of cellular response to stressGO:00801351590.036
immune effector processGO:00022523210.036
cellular amino acid metabolic processGO:00065201030.035
cytokine productionGO:00018163190.035
Mouse
positive regulation of protein serine threonine kinase activityGO:00719021060.035
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.035
regulation of t cell activationGO:00508631700.034
Mouse
positive regulation of eosinophil migrationGO:200041820.034
Mouse
ribonucleoside metabolic processGO:00091192450.034
peptidyl amino acid modificationGO:00181933360.034
nucleoside phosphate metabolic processGO:00067533380.034
myotube differentiationGO:00149021050.034
negative regulation of immune system processGO:00026832090.033
regulation of membrane potentialGO:00423911920.033
Mouse
potassium ion transmembrane transportGO:0071805430.032
cell adhesionGO:00071553290.032
Mouse
carbohydrate derivative catabolic processGO:19011362310.032
macromolecule catabolic processGO:00090572810.032
Mouse
purine ribonucleoside metabolic processGO:00461282410.031
regulation of protein transportGO:00512231630.031
regulation of cell migrationGO:00303342190.031
Mouse
nucleoside triphosphate catabolic processGO:00091432050.031
positive regulation of nervous system developmentGO:00519622210.030
peptidyl tyrosine phosphorylationGO:00181081430.030
cellular response to cytokine stimulusGO:00713451890.030
cellular nitrogen compound catabolic processGO:00442702800.030
negative regulation of intracellular signal transductionGO:19025321670.030
ribose phosphate metabolic processGO:00196932910.029
glycosyl compound metabolic processGO:19016572460.029
purine containing compound metabolic processGO:00725213110.029
negative regulation of protein metabolic processGO:00512482820.029
regulation of ion transportGO:00432692150.029
transmembrane transportGO:00550854120.029
regulation of striated muscle cell differentiationGO:0051153810.028
regulation of cell cycleGO:00517262810.028
striated muscle tissue developmentGO:00147062930.028
regulation of leukocyte differentiationGO:19021051590.028
Mouse
negative regulation of phosphorylationGO:00423261660.027
nucleoside metabolic processGO:00091162460.027
nucleoside phosphate catabolic processGO:19012922220.027
innate immune responseGO:00450871570.027
Mouse
ion transmembrane transportGO:00342203610.027
b cell activationGO:00421131610.027
Mouse
leukocyte mediated immunityGO:00024431740.026
cell chemotaxisGO:0060326810.026
Mouse
inorganic ion transmembrane transportGO:00986602340.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.026
purine ribonucleoside triphosphate metabolic processGO:00092052200.026
regulation of kinase activityGO:00435492490.026
Mouse
reactive nitrogen species metabolic processGO:200105700.026
purine nucleoside triphosphate catabolic processGO:00091462030.026
ribonucleoside catabolic processGO:00424542060.025
regulation of mapk cascadeGO:00434082480.025
Mouse
cellularizationGO:000734910.025
developmental maturationGO:00217001930.025
positive regulation of cellular amine metabolic processGO:003324050.025
regulation of cellular component biogenesisGO:00440871810.025
skin developmentGO:00435882200.025
purine nucleoside metabolic processGO:00422782410.025
epidermis developmentGO:00085441870.025
organic hydroxy compound metabolic processGO:19016152030.025
adaptive immune responseGO:00022501550.025
Mouse
g protein coupled receptor signaling pathwayGO:00071862430.024
lymphocyte differentiationGO:00300982420.024
Mouse
ras protein signal transductionGO:0007265770.024
neuronal action potentialGO:0019228540.024
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.024
Mouse
nucleotide catabolic processGO:00091662170.024
purine ribonucleoside catabolic processGO:00461302050.024
cellular response to oxidative stressGO:0034599760.024
cellular response to biotic stimulusGO:0071216920.024
positive regulation of programmed cell deathGO:00430682180.024
Mouse
synaptic transmissionGO:00072683290.024
multicellular organismal homeostasisGO:00488711640.024
Mouse
response to lipopolysaccharideGO:00324961280.024
heterocycle catabolic processGO:00467002800.024
nucleoside triphosphate metabolic processGO:00091412300.023
regulation of thymocyte migrationGO:200041020.023
Mouse
lymphocyte activation involved in immune responseGO:0002285930.023
tissue homeostasisGO:00018941150.023
Mouse
positive regulation of kinase activityGO:00336741550.023
Mouse
angiogenesisGO:00015252010.023
Mouse
regulation of hydrolase activityGO:00513362460.022
organonitrogen compound catabolic processGO:19015652640.022
purine nucleoside catabolic processGO:00061522050.022
cellular chemical homeostasisGO:00550822150.022
peptidyl tyrosine modificationGO:00182121450.021
positive regulation of cytokine productionGO:00018191740.021
Mouse
cellular response to hormone stimulusGO:00328701500.021
regulation of lymphocyte differentiationGO:00456191070.021
Mouse
positive regulation of defense responseGO:00313491240.021
Mouse
spermatid differentiationGO:00485151150.021
purine nucleotide metabolic processGO:00061633020.021
glycosyl compound catabolic processGO:19016582060.021
dna metabolic processGO:00062593030.021
membrane organizationGO:00610242450.021
regulation of organelle organizationGO:00330432890.021
positive regulation of transferase activityGO:00513471670.021
Mouse
response to growth factorGO:00708481980.021
Mouse
meiotic nuclear divisionGO:00071261150.020
cellular homeostasisGO:00197252400.020
muscle cell differentiationGO:00426922610.020
purine ribonucleotide catabolic processGO:00091542080.020
cation transmembrane transportGO:00986552660.020
defense response to virusGO:0051607680.020
aromatic compound catabolic processGO:00194392860.020
regulation of microvillus assemblyGO:003253430.020
purine nucleotide catabolic processGO:00061952110.020
anatomical structure homeostasisGO:00602491450.020
Mouse
neuron apoptotic processGO:00514021420.020
Mouse
regulation of cytoplasmic transportGO:19036491120.019
i kappab kinase nf kappab signalingGO:0007249850.019
cellular response to growth factor stimulusGO:00713631970.019
Mouse
leukocyte proliferationGO:00706611720.019
intracellular protein transportGO:00068862040.019
lymphocyte proliferationGO:00466511640.019
cellular macromolecule catabolic processGO:00442652060.019
anion transportGO:00068201770.019
protein processingGO:00164851630.019
activation of mapk activityGO:0000187590.018
Mouse
regulation of multi organism processGO:00439001110.018
Mouse
cell type specific apoptotic processGO:00972852680.018
Mouse
b cell proliferationGO:0042100530.018
nuclear transportGO:00511691390.018
rho protein signal transductionGO:0007266320.018
positive regulation of protein transportGO:0051222930.018
rna interferenceGO:001624620.018
regulation of defense response to bacteriumGO:190042430.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
engulfment of apoptotic cellGO:004365230.018
regulation of lymphocyte mediated immunityGO:0002706840.018
immune response regulating signaling pathwayGO:00027641250.018
Mouse
negative regulation of angiogenesisGO:0016525250.018
lymphocyte mediated immunityGO:00024491390.018
positive regulation of t cell activationGO:00508701010.017
Mouse
regulation of t cell differentiationGO:0045580830.017
Mouse
regulation of cell adhesionGO:00301551540.017
Mouse
peptidyl serine modificationGO:0018209830.017
positive regulation of ion transportGO:0043270650.017
positive regulation of cellular catabolic processGO:00313311480.017
Mouse
negative regulation of lymphocyte activationGO:0051250910.017
oxidation reduction processGO:00551143420.017
negative regulation of cellular protein metabolic processGO:00322692470.017
posttranscriptional regulation of gene expressionGO:00106081550.017
protein localization to organelleGO:00333651850.017
axon ensheathmentGO:0008366760.017
Mouse
regulation of body fluid levelsGO:00508781620.017
protein secretionGO:00093061110.017
regulation of vasculature developmentGO:1901342880.016
germ cell developmentGO:00072811850.016
leukocyte differentiationGO:00025213420.016
Mouse
regulation of circadian sleep wake cycle sleepGO:004518730.016
nitrogen compound transportGO:00717052710.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
cellular amide metabolic processGO:0043603580.016
negative regulation of leukocyte mediated immunityGO:0002704290.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
protein catabolic processGO:00301632210.016
Mouse
regulation of neuron projection developmentGO:00109751690.016
regulation of t helper 2 cell cytokine productionGO:200055130.016
skeletal muscle fiber developmentGO:0048741580.016
regulation of inflammatory responseGO:00507271470.016
Mouse
regulation of skeletal muscle fiber developmentGO:0048742360.015
regulation of lipid metabolic processGO:00192161180.015
nucleoside catabolic processGO:00091642060.015
b cell differentiationGO:0030183780.015
Mouse
regulation of nucleocytoplasmic transportGO:0046822730.015
single fertilizationGO:0007338820.015
Mouse
stress activated protein kinase signaling cascadeGO:0031098810.015
positive regulation of innate immune responseGO:0045089800.015
Mouse
regulation of leukocyte mediated immunityGO:00027031040.015
single organism cell adhesionGO:00986021560.015
Mouse
negative regulation of immune effector processGO:0002698550.015
cellular response to dna damage stimulusGO:00069742070.015
production of molecular mediator of immune responseGO:00024401030.015
cellular response to lipopolysaccharideGO:0071222770.015
eosinophil migrationGO:007267730.015
Mouse
response to molecule of bacterial originGO:00022371430.015
nucleocytoplasmic transportGO:00069131390.015
positive regulation of secretionGO:00510471300.015
negative regulation of muscle cell differentiationGO:0051148330.015
regulation of cellular component sizeGO:00325351210.015
negative regulation of hydrolase activityGO:0051346710.015
regulation of leukocyte proliferationGO:00706631210.015
regulation of peptidyl tyrosine phosphorylationGO:0050730930.015
response to oxidative stressGO:00069791230.015
regulation of intracellular protein transportGO:0033157820.015
regulation of cellular catabolic processGO:00313292420.014
Mouse
negative regulation of vasculature developmentGO:1901343260.014
osteoclast differentiationGO:0030316620.014
organic anion transportGO:00157111370.014
sensory organ morphogenesisGO:00905962420.014
regulation of map kinase activityGO:00434051200.014
Mouse
endocytosisGO:00068971680.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.014
t cell mediated immunityGO:0002456500.014
positive regulation of mapk cascadeGO:00434101700.014
Mouse
negative regulation of response to woundingGO:1903035770.014
glycosylationGO:0070085620.014
organonitrogen compound biosynthetic processGO:19015661920.014
regulation of myotube differentiationGO:0010830620.014
cation transportGO:00068123990.014
negative regulation of cell developmentGO:00107211690.014
multicellular organismal signalingGO:0035637910.014
Mouse
regulation of action potentialGO:009890040.014
peptide metabolic processGO:0006518460.014
negative regulation of phosphorus metabolic processGO:00105631840.014
positive regulation of cell deathGO:00109422240.014
Mouse
glycoprotein metabolic processGO:00091001160.014
microtubule based processGO:00070172360.014
negative regulation of protein modification processGO:00314001630.014
defense response to other organismGO:00985421970.014
cd4 positive alpha beta t cell cytokine productionGO:003574340.013
ribonucleoside monophosphate catabolic processGO:0009158570.013
negative regulation of cell activationGO:00508661110.013
homeostasis of number of cellsGO:00488722100.013
Mouse
glycoprotein biosynthetic processGO:0009101890.013
ensheathment of neuronsGO:0007272760.013
Mouse
antibacterial peptide productionGO:000277820.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
establishment of protein localization to organelleGO:00725941180.013
protein modification by small protein conjugation or removalGO:00706472070.013
neuron deathGO:00709971540.013
Mouse
regulation of antibacterial peptide productionGO:000278610.013
erk1 and erk2 cascadeGO:0070371770.013
pigmentationGO:0043473710.013
learning or memoryGO:00076111480.013
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.013
methylationGO:00322591340.013
positive regulation of cell developmentGO:00107202370.013
spermatid developmentGO:00072861080.013
regulation of cytokine secretionGO:0050707610.012
cellular response to organonitrogen compoundGO:00714171450.012
reactive oxygen species metabolic processGO:0072593840.012
gland developmentGO:00487323300.012
negative regulation of cellular component organizationGO:00511291940.012
t helper 2 cell cytokine productionGO:003574540.012
atp catabolic processGO:0006200550.012
myeloid cell differentiationGO:00300992330.012
stem cell differentiationGO:00488632680.012
Mouse
regulation of response to woundingGO:19030341890.012
Mouse
ear morphogenesisGO:00424711180.012
regulation of innate immune responseGO:0045088910.012
Mouse
protein import into nucleusGO:0006606950.012
positive regulation of cell activationGO:00508671580.012
Mouse
regulation of cell motilityGO:20001452360.012
Mouse
negative regulation of blood vessel morphogenesisGO:2000181250.012
positive regulation of defense response to bacteriumGO:190042610.012
organophosphate biosynthetic processGO:00904071220.012
dendrite developmentGO:00163581150.012
thymocyte migrationGO:007267920.012
Mouse
atp metabolic processGO:0046034750.012
myotube cell developmentGO:0014904600.012
hepaticobiliary system developmentGO:0061008670.012
forebrain developmentGO:00309003020.012
photoreceptor cell differentiationGO:0046530520.012
single organismal cell cell adhesionGO:00163371310.012
Mouse
antibacterial peptide biosynthetic processGO:000278020.012
regulation of interleukin 6 productionGO:0032675550.012
positive regulation of intracellular transportGO:0032388700.012
reactive oxygen species biosynthetic processGO:190340980.012
cell cell recognitionGO:0009988440.011
Mouse
nucleoside monophosphate catabolic processGO:0009125590.011
transmission of nerve impulseGO:0019226760.011
Mouse
negative regulation of nervous system developmentGO:00519611560.011
regulation of protein maturationGO:1903317960.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
regulation of membrane protein ectodomain proteolysisGO:005104330.011
Mouse
positive regulation of apoptotic processGO:00430652170.011
Mouse
sensory perception of chemical stimulusGO:0007606510.011
lateral inhibitionGO:004633110.011
dna methylation involved in gamete generationGO:0043046150.011
regulation of purine nucleotide metabolic processGO:19005421690.011
response to radiationGO:00093141650.011
Mouse
regulation of response to biotic stimulusGO:0002831380.011
muscle fiber developmentGO:0048747760.011
positive regulation of insulin receptor signaling pathwayGO:004662840.011
regulation of anatomical structure sizeGO:00900661780.011
regulation of metal ion transportGO:00109591060.011
asymmetric stem cell divisionGO:009872230.011
regulation of peptidase activityGO:0052547960.011
protein modification by small protein conjugationGO:00324461870.011
sperm motilityGO:0030317470.011
positive regulation of interleukin 18 productionGO:003274120.011
muscle cell developmentGO:00550011330.011
negative regulation of cytokine productionGO:0001818840.011
carbohydrate metabolic processGO:00059752300.011
leukocyte migrationGO:00509001240.011
Mouse
negative regulation of phosphate metabolic processGO:00459361840.011
positive regulation of cell projection organizationGO:0031346950.011
regulation of muscle tissue developmentGO:1901861970.011
regulation of circadian sleep wake cycleGO:004274930.011
regulation of secretion by cellGO:19035302490.011
cellular metal ion homeostasisGO:00068751510.011
regionalizationGO:00030023370.011
positive regulation of growthGO:00459271040.011
negative regulation of interleukin 13 productionGO:003269620.011
respiratory gaseous exchangeGO:0007585430.010
dephosphorylationGO:00163111290.010
positive regulation of cell migrationGO:00303351090.010
Mouse
gtp metabolic processGO:00460391440.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
myeloid leukocyte migrationGO:0097529570.010
Mouse
anion transmembrane transportGO:0098656710.010
cytokine production involved in immune responseGO:0002367340.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
regulation of neuron apoptotic processGO:00435231220.010
Mouse
activation of immune responseGO:00022531380.010
Mouse
multicellular organism growthGO:00352641610.010
rna processingGO:00063961050.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
negative regulation of t cell activationGO:0050868650.010
sensory perception of light stimulusGO:0050953540.010
defense response to bacteriumGO:00427421190.010
multi multicellular organism processGO:00447061090.010
sperm individualizationGO:000729110.010
renal system developmentGO:00720012250.010
organelle localizationGO:00516401790.010
cellular lipid metabolic processGO:00442553230.010
jnk cascadeGO:0007254720.010
negative regulation of blood vessel endothelial cell migrationGO:004353730.010
pirna metabolic processGO:0034587120.010
cellular response to molecule of bacterial originGO:0071219830.010
negative regulation of myoblast differentiationGO:0045662180.010

Adam21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.027
cancerDOID:16200.024
organ system cancerDOID:005068600.024
disease of metabolismDOID:001466700.012
immune system diseaseDOID:291400.010
disease of anatomical entityDOID:700.010