Mus musculus

18 known processes

Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

(Aliases: Mirk)

Dyrk1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gland developmentGO:00487323300.301
regulation of cell cycleGO:00517262810.172
negative regulation of cell proliferationGO:00082852960.172
regulation of protein transportGO:00512231630.157
regulation of protein localizationGO:00328802310.147
peptidyl amino acid modificationGO:00181933360.145
Yeast Mouse
regulation of cellular amino acid metabolic processGO:000652150.138
positive regulation of cellular amine metabolic processGO:003324050.136
t cell proliferationGO:00420981200.135
negative regulation of phosphate metabolic processGO:00459361840.129
regulation of cardioblast differentiationGO:005189030.126
regulation of bindingGO:00510981110.122
cellular response to dna damage stimulusGO:00069742070.114
Mouse
nucleoside phosphate metabolic processGO:00067533380.110
cellular component assembly involved in morphogenesisGO:00109271390.108
divalent metal ion transportGO:00708381720.105
cellular nitrogen compound catabolic processGO:00442702800.103
homeostasis of number of cellsGO:00488722100.100
Mouse
dna metabolic processGO:00062593030.097
regulation of secretionGO:00510462740.095
response to light stimulusGO:00094161350.094
response to radiationGO:00093141650.093
organelle assemblyGO:00709251770.090
positive regulation of cellular amino acid metabolic processGO:004576430.086
divalent inorganic cation transportGO:00725111780.084
purine nucleotide metabolic processGO:00061633020.083
nucleobase containing small molecule metabolic processGO:00550863520.081
nucleotide metabolic processGO:00091173320.081
directional locomotionGO:003305830.081
respiratory system developmentGO:00605411900.079
regulation of membrane potentialGO:00423911920.077
organic cyclic compound catabolic processGO:19013612950.075
cellular amine metabolic processGO:0044106440.074
negative regulation of leukocyte differentiationGO:1902106510.073
cytoplasmic transportGO:00164822340.068
negative regulation of protein modification processGO:00314001630.066
lung developmentGO:00303241640.066
regulation of ossificationGO:00302781120.065
striated muscle tissue developmentGO:00147062930.064
negative regulation of lymphocyte activationGO:0051250910.063
response to oxidative stressGO:00069791230.063
lipid homeostasisGO:0055088630.062
nuclear transportGO:00511691390.060
cellular ketone metabolic processGO:0042180840.060
regulation of cell activationGO:00508652890.059
embryonic epithelial tube formationGO:00018381300.059
response to insulinGO:00328681000.059
nucleotide catabolic processGO:00091662170.056
negative regulation of protein metabolic processGO:00512482820.056
purine containing compound metabolic processGO:00725213110.055
regulation of establishment of protein localizationGO:00702011810.055
calcium ion transportGO:00068161590.054
positive regulation of peroxisome proliferator activated receptor signaling pathwayGO:003536020.052
meiotic cell cycleGO:00513211220.052
autonomic nervous system developmentGO:0048483430.051
protein targetingGO:00066051430.050
negative regulation of phosphorylationGO:00423261660.049
heterocycle catabolic processGO:00467002800.049
tube formationGO:00351481400.049
peptidyl serine modificationGO:0018209830.048
Mouse
spermatogenesisGO:00072832840.047
stem cell differentiationGO:00488632680.047
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.047
carbohydrate homeostasisGO:00335001280.046
ribose phosphate metabolic processGO:00196932910.044
phosphatidic acid biosynthetic processGO:000665420.043
cellular macromolecule catabolic processGO:00442652060.042
carbohydrate derivative catabolic processGO:19011362310.042
intracellular protein transportGO:00068862040.042
negative regulation of immune system processGO:00026832090.041
gonadotrophin releasing hormone neuronal migration to the hypothalamusGO:002182830.041
negative regulation of phosphorus metabolic processGO:00105631840.041
organelle fissionGO:00482851700.041
positive regulation of apoptotic processGO:00430652170.041
glial cell developmentGO:0021782540.040
epithelial tube formationGO:00721751300.040
lymphocyte differentiationGO:00300982420.040
myeloid cell differentiationGO:00300992330.040
Mouse
apoptotic signaling pathwayGO:00971903060.038
mapk cascadeGO:00001652810.038
regulation of lymphocyte activationGO:00512492400.038
wound healingGO:00420601570.038
negative regulation of protein transportGO:0051224460.038
atrioventricular node developmentGO:000316230.038
cellular response to hormone stimulusGO:00328701500.037
sensory perceptionGO:00076002450.037
nuclear divisionGO:00002801580.036
microtubule based processGO:00070172360.036
dna repairGO:00062811070.036
limb developmentGO:00601731660.036
divalent inorganic cation homeostasisGO:00725071380.036
generation of precursor metabolites and energyGO:00060911030.036
positive regulation of protein phosphorylationGO:00019342420.035
development of primary sexual characteristicsGO:00451371430.035
regulation of organelle organizationGO:00330432890.035
regulation of cellular amine metabolic processGO:0033238200.035
myeloid cell homeostasisGO:00022621140.034
Mouse
metal ion homeostasisGO:00550651890.034
lymphocyte activation involved in immune responseGO:0002285930.034
neuroblast differentiationGO:001401620.034
regulation of ion transmembrane transportGO:00347651190.034
morphogenesis of embryonic epitheliumGO:00163311590.034
neural precursor cell proliferationGO:00613511210.034
ribonucleoside metabolic processGO:00091192450.034
mitotic cell cycleGO:00002781950.034
neural tube closureGO:0001843900.033
organophosphate catabolic processGO:00464342320.033
regulation of cytoplasmic transportGO:19036491120.033
polysaccharide metabolic processGO:0005976390.032
purine nucleoside catabolic processGO:00061522050.032
meiotic nuclear divisionGO:00071261150.032
amine metabolic processGO:0009308450.032
nucleocytoplasmic transportGO:00069131390.032
rhythmic processGO:00485111740.031
Mouse
positive regulation of proteolysisGO:0045862850.031
aromatic compound catabolic processGO:00194392860.030
positive regulation of programmed cell deathGO:00430682180.030
cellular response to organonitrogen compoundGO:00714171450.030
protein secretionGO:00093061110.030
negative regulation of cell sizeGO:004579230.030
positive regulation of nucleotide metabolic processGO:00459811140.030
organophosphate biosynthetic processGO:00904071220.030
sequestering of metal ionGO:0051238190.029
actin cytoskeleton organizationGO:00300362200.029
purine nucleoside metabolic processGO:00422782410.029
glial cell fate commitmentGO:0021781140.029
cellular homeostasisGO:00197252400.029
negative regulation of cellular protein metabolic processGO:00322692470.029
heart inductionGO:000312920.029
immune effector processGO:00022523210.029
positive regulation of transcription via serum response element bindingGO:001073510.029
glucose homeostasisGO:00425931280.028
cellular response to insulin stimulusGO:0032869780.028
negative regulation of t cell activationGO:0050868650.028
multicellular organismal homeostasisGO:00488711640.028
adherens junction maintenanceGO:003433410.027
regulation of metal ion transportGO:00109591060.027
cellular divalent inorganic cation homeostasisGO:00725031270.027
regulation of nucleotide metabolic processGO:00061401690.026
posttranscriptional regulation of gene expressionGO:00106081550.026
purine ribonucleoside triphosphate catabolic processGO:00092071990.026
gtp metabolic processGO:00460391440.026
membrane lipid biosynthetic processGO:0046467320.026
rho protein signal transductionGO:0007266320.026
cerebral cortex tangential migration using cell axon interactionsGO:002182430.026
mitotic cell cycle processGO:19030471590.025
i kappab kinase nf kappab signalingGO:0007249850.025
t cell differentiationGO:00302171740.025
positive regulation of protein modification processGO:00314012990.025
Mouse
defense response to virusGO:0051607680.025
regulation of carbohydrate biosynthetic processGO:0043255400.025
cellular calcium ion homeostasisGO:00068741190.025
regulation of apoptotic signaling pathwayGO:20012331970.025
hypothalamus cell differentiationGO:002197980.025
membrane organizationGO:00610242450.025
regulation of mapk cascadeGO:00434082480.025
development of primary male sexual characteristicsGO:0046546880.025
cell junction maintenanceGO:003433140.024
lipid biosynthetic processGO:00086101790.024
behavioral response to nutrientGO:005178010.024
regulation of purine nucleotide metabolic processGO:19005421690.024
nucleoside phosphate catabolic processGO:19012922220.024
establishment of organelle localizationGO:00516561220.024
protein localization to organelleGO:00333651850.024
purine nucleotide catabolic processGO:00061952110.024
purine nucleotide biosynthetic processGO:0006164650.024
blood circulationGO:00080151950.024
establishment of protein localization to organelleGO:00725941180.024
endomembrane system organizationGO:00102561470.024
establishment or maintenance of cell polarityGO:0007163860.024
negative regulation of cellular amine metabolic processGO:003323910.024
muscular septum morphogenesisGO:000315040.024
b cell activationGO:00421131610.024
forebrain developmentGO:00309003020.024
purine ribonucleotide metabolic processGO:00091502900.023
synaptic vesicle membrane organizationGO:004849910.023
respiratory tube developmentGO:00303231670.023
developmental maturationGO:00217001930.023
facioacoustic ganglion developmentGO:190337530.023
regulation of mitotic cell cycleGO:00073461260.023
leukocyte homeostasisGO:0001776790.023
nucleoside metabolic processGO:00091162460.023
microtubule cytoskeleton organizationGO:00002261570.023
glucan metabolic processGO:0044042320.022
organonitrogen compound catabolic processGO:19015652640.022
male gamete generationGO:00482322850.022
intracellular receptor signaling pathwayGO:0030522740.022
negative regulation of lymphocyte differentiationGO:0045620320.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
cellular amino acid metabolic processGO:00065201030.022
reactive oxygen species metabolic processGO:0072593840.022
g protein coupled receptor signaling pathwayGO:00071862430.022
regulation of secretion by cellGO:19035302490.022
cell divisionGO:00513011200.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
bone mineralizationGO:0030282540.022
nuclear importGO:0051170950.021
signal transduction by p53 class mediatorGO:0072331510.021
Mouse
canonical wnt signaling pathwayGO:00600701300.021
hypothalamus gonadotrophin releasing hormone neuron developmentGO:002188840.021
skeletal system developmentGO:00015013560.021
cellularizationGO:000734910.021
germ cell developmentGO:00072811850.021
energy derivation by oxidation of organic compoundsGO:0015980770.021
sequestering of calcium ionGO:0051208180.021
positive regulation of neuron apoptotic processGO:0043525250.021
glial cell differentiationGO:00100011310.021
spermatid differentiationGO:00485151150.021
sphingolipid biosynthetic processGO:0030148260.021
regulation of leukocyte differentiationGO:19021051590.020
epithelial tube morphogenesisGO:00605623030.020
peptide secretionGO:00027901140.020
stem cell maintenanceGO:00198271300.020
response to lipopolysaccharideGO:00324961280.020
cyclic nucleotide metabolic processGO:0009187590.020
positive regulation of interleukin 1 alpha secretionGO:005071730.020
regulation of leukocyte proliferationGO:00706631210.020
regulation of vascular smooth muscle contractionGO:000305610.020
guanosine containing compound metabolic processGO:19010681440.020
cell cycle switching mitotic to meiotic cell cycleGO:005172810.020
male gonad developmentGO:0008584880.020
trunk neural crest cell migrationGO:003648440.019
regulation of sequence specific dna binding transcription factor activityGO:00510901060.019
peptidyl tyrosine modificationGO:00182121450.019
Yeast Mouse
multicellular organism growthGO:00352641610.019
regulation of actin filament based processGO:0032970990.019
ribonucleotide metabolic processGO:00092592910.019
positive regulation of purine nucleotide metabolic processGO:19005441140.019
regulation of reactive oxygen species metabolic processGO:2000377400.019
semaphorin plexin signaling pathway involved in bone trabecula morphogenesisGO:190022020.019
asymmetric stem cell divisionGO:009872230.019
response to oxygen levelsGO:0070482620.018
purine ribonucleotide catabolic processGO:00091542080.018
ribonucleotide catabolic processGO:00092612080.018
anatomical structure homeostasisGO:00602491450.018
stem cell developmentGO:00488642190.018
protein localization to nucleusGO:00345041210.018
cell type specific apoptotic processGO:00972852680.018
tissue homeostasisGO:00018941150.018
spermatid developmentGO:00072861080.018
muscle tissue developmentGO:00605373080.018
macromolecule catabolic processGO:00090572810.018
proteolysis involved in cellular protein catabolic processGO:00516031470.018
alpha beta t cell activationGO:0046631910.018
cellular response to abiotic stimulusGO:0071214560.018
olfactory learningGO:000835520.018
regulation of canonical wnt signaling pathwayGO:0060828820.018
positive regulation of protein transportGO:0051222930.018
purine containing compound catabolic processGO:00725232130.017
sympathetic neuron projection extensionGO:009749040.017
protein modification by small protein conjugationGO:00324461870.017
leukocyte differentiationGO:00025213420.017
glycosyl compound metabolic processGO:19016572460.017
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.017
negative regulation of cell fate specificationGO:000999640.017
regulation of neuron apoptotic processGO:00435231220.017
regulation of protein kinase activityGO:00458592320.017
response to inorganic substanceGO:0010035960.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
central nervous system neuron differentiationGO:00219531620.017
neural tube developmentGO:00219151600.017
gonad developmentGO:00084061410.017
defecationGO:003042110.017
negative regulation of t cell differentiationGO:0045581230.017
adult behaviorGO:00305341350.017
muscle cell differentiationGO:00426922610.017
cellular response to oxidative stressGO:0034599760.017
negative regulation of wnt signaling pathwayGO:0030178730.017
regulation of lymphocyte proliferationGO:00506701170.017
sympathetic neuron projection guidanceGO:009749140.016
viral processGO:0016032410.016
negative regulation of cell cycleGO:00457861230.016
regulation of cell cycle processGO:00105641600.016
guanosine containing compound catabolic processGO:19010691440.016
cellular response to peptideGO:1901653920.016
hindbrain developmentGO:00309021280.016
natural killer cell activationGO:0030101440.016
cellular chemical homeostasisGO:00550822150.016
feeding behaviorGO:0007631620.016
proepicardium developmentGO:000334220.016
entry into hostGO:0044409150.016
spinal cord oligodendrocyte cell differentiationGO:002152930.016
regulation of t cell activationGO:00508631700.016
cofactor biosynthetic processGO:0051188410.016
negative regulation of interleukin 5 productionGO:003271440.016
glycogen metabolic processGO:0005977320.016
protein import into nucleusGO:0006606950.015
regulation of wnt signaling pathwayGO:00301111230.015
b cell differentiationGO:0030183780.015
glutamate receptor signaling pathwayGO:0007215350.015
cell fate commitmentGO:00451652100.015
regulation of intracellular protein transportGO:0033157820.015
fat cell differentiationGO:00454441600.015
energy reserve metabolic processGO:0006112390.015
positive regulation of bindingGO:0051099490.015
vesicle organizationGO:0016050600.015
carbohydrate biosynthetic processGO:0016051740.015
ribonucleotide biosynthetic processGO:0009260590.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
neuron apoptotic processGO:00514021420.015
synapse organizationGO:00508081250.015
canonical wnt signaling pathway involved in heart developmentGO:006131630.015
response to uvGO:0009411440.015
spermatid nucleus differentiationGO:0007289190.015
trunk segmentationGO:003529040.015
regulation of b cell activationGO:0050864810.014
regulation of heart inductionGO:009038120.014
cation transportGO:00068123990.014
cellular response to lipopolysaccharideGO:0071222770.014
fucosylationGO:003606590.014
regulation of cardiac muscle contractionGO:0055117210.014
protein localization to membraneGO:00726571080.014
regulation of transmembrane transportGO:00347621280.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
macromolecule methylationGO:00434141200.014
ribonucleoside catabolic processGO:00424542060.014
ventricular system developmentGO:0021591270.014
extracellular structure organizationGO:00430621480.014
polysaccharide biosynthetic processGO:0000271200.014
neurohypophysis developmentGO:002198520.014
regulation of lymphocyte apoptotic processGO:0070228410.014
protein catabolic processGO:00301632210.014
methylationGO:00322591340.014
lymphocyte proliferationGO:00466511640.014
nucleus organizationGO:0006997450.014
mrna metabolic processGO:0016071840.014
Mouse
response to peptide hormoneGO:00434341270.014
cellular metal ion homeostasisGO:00068751510.014
sperm individualizationGO:000729110.014
regulation of carbohydrate metabolic processGO:0006109750.014
single organism nuclear importGO:1902593950.013
regulation of cytokine productionGO:00018172660.013
regulation of myeloid cell differentiationGO:0045637960.013
negative regulation of cell activationGO:00508661110.013
regulation of nucleocytoplasmic transportGO:0046822730.013
transmission of nerve impulseGO:0019226760.013
oligodendrocyte developmentGO:0014003200.013
negative regulation of neuron apoptotic processGO:0043524920.013
t cell activationGO:00421102890.013
cation homeostasisGO:00550802120.013
regulation of calcium ion transportGO:0051924690.013
interaction with hostGO:0051701220.013
carbohydrate derivative biosynthetic processGO:19011371830.013
b cell proliferationGO:0042100530.013
regulation of intracellular transportGO:00323861590.013
male sex differentiationGO:00466611090.013
regulation of interleukin 1 alpha secretionGO:005070530.013
peptidyl serine phosphorylationGO:0018105740.013
Mouse
liver developmentGO:0001889660.013
negative regulation of molecular functionGO:00440922580.013
regulation of system processGO:00440572000.013
leukocyte proliferationGO:00706611720.013
branching morphogenesis of an epithelial tubeGO:00487541590.013
negative regulation of secretion by cellGO:1903531540.013
cell fate determination involved in pattern specificationGO:006058210.013
mucosal associated lymphoid tissue developmentGO:0048537120.013
regulation of transporter activityGO:0032409570.013
negative regulation of intracellular signal transductionGO:19025321670.012
Mouse
mitotic nuclear divisionGO:0007067480.012
myotube differentiationGO:00149021050.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
hypothalamic tangential migration using cell axon interactionsGO:002185630.012
midgut developmentGO:000749440.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
positive regulation of hydrolase activityGO:00513451480.012
neural tube formationGO:00018411080.012
cellular ion homeostasisGO:00068731650.012
fourth ventricle developmentGO:002159220.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
glycoprotein metabolic processGO:00091001160.012
regulation of circadian rhythmGO:0042752580.012
axonogenesisGO:00074092740.012
lymphocyte apoptotic processGO:0070227540.012
glycosyl compound catabolic processGO:19016582060.012
purine ribonucleoside catabolic processGO:00461302050.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
protein ubiquitinationGO:00165671710.012
cardiac cell fate specificationGO:006091220.012
protein importGO:00170381010.012
response to organonitrogen compoundGO:00102432460.012
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.012
regulation of lateral mesodermal cell fate specificationGO:004837820.012
atrioventricular node cell differentiationGO:006092220.012
signal transduction in absence of ligandGO:0038034550.012
regulation of protein secretionGO:0050708820.012
wnt signaling pathwayGO:00160551880.012
carbohydrate metabolic processGO:00059752300.012
regulation of neuron deathGO:19012141340.012
rna interferenceGO:001624620.012
glycogen biosynthetic processGO:0005978140.012
cytokinetic processGO:003250620.012
regulation of protein kinase b signalingGO:0051896560.012
striated muscle contractionGO:0006941450.011
t cell differentiation in thymusGO:0033077770.011
mitochondrion organizationGO:00070051340.011
negative regulation of sterol transportGO:003237240.011
regulation of striated muscle contractionGO:0006942250.011
positive regulation of cell developmentGO:00107202370.011
organonitrogen compound biosynthetic processGO:19015661920.011
septum transversum developmentGO:000334320.011
regulation of ion transmembrane transporter activityGO:0032412540.011
negative regulation of t cell proliferationGO:0042130380.011
positive regulation of cell deathGO:00109422240.011
positive regulation of protein kinase activityGO:00458601440.011
multicellular organismal macromolecule catabolic processGO:004426610.011
somatotropin secreting cell developmentGO:006013320.011
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.011
ventral trunk neural crest cell migrationGO:003648640.011
modification dependent protein catabolic processGO:00199411330.011
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.011
adaptive immune responseGO:00022501550.011
cellular response to lipidGO:00713961450.011
regulation of notch signaling pathwayGO:0008593350.011
regulation of urine volumeGO:003580960.011
cellular response to external stimulusGO:0071496880.011
ossificationGO:00015032160.011
regulation of cell divisionGO:0051302760.011
regulation of protein serine threonine kinase activityGO:00719001570.011
negative regulation of leukocyte proliferationGO:0070664460.011
hypothalamus gonadotrophin releasing hormone neuron differentiationGO:002188640.011
negative regulation of mapk cascadeGO:0043409650.011
regulation of mitochondrial membrane potentialGO:0051881170.011
glucan biosynthetic processGO:0009250140.011
regionalizationGO:00030023370.011
pulmonary myocardium developmentGO:000335030.011
alpha beta t cell differentiationGO:0046632690.011
regulation of ion transportGO:00432692150.011
positive regulation of secretion by cellGO:19035321140.011
lung alveolus developmentGO:0048286450.011
regulation of cell shapeGO:0008360390.011
regulation of epithelial cell proliferationGO:00506781410.011
negative regulation of lymphocyte proliferationGO:0050672450.011
regulation of cellular ketone metabolic processGO:0010565660.011
cellular lipid metabolic processGO:00442553230.011
heart field specificationGO:000312860.011
positive regulation of notch signaling pathwayGO:0045747180.011
smoothened signaling pathwayGO:00072241050.011
regulation of response to dna damage stimulusGO:2001020340.011
Mouse
response to transforming growth factor betaGO:0071559880.010
interleukin 1 alpha secretionGO:005070330.010
positive regulation of organelle organizationGO:00106381280.010
leukocyte apoptotic processGO:0071887710.010
positive regulation of map kinase activityGO:0043406840.010
negative regulation of protein phosphorylationGO:00019331260.010
apoptotic process involved in mammary gland involutionGO:006005740.010
amino acid import into cellGO:190283740.010
regulation of cellular catabolic processGO:00313292420.010
epithelial cell proliferationGO:00506731740.010
amino acid uptake involved in synaptic transmissionGO:005193330.010
response to acid chemicalGO:00011011110.010
multicellular organismal signalingGO:0035637910.010
establishment of protein localization to membraneGO:0090150540.010
positive regulation of cardioblast differentiationGO:005189130.010
negative regulation of cellular amino acid metabolic processGO:004576300.010
cellular carbohydrate metabolic processGO:00442621190.010
regulation of lymphocyte differentiationGO:00456191070.010
negative regulation of protein secretionGO:0050709200.010
histone modificationGO:00165701590.010
notch signaling pathwayGO:0007219710.010
small molecule biosynthetic processGO:00442831320.010
regulation of protein bindingGO:0043393600.010
oxidation reduction processGO:00551143420.010

Dyrk1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.032
cancerDOID:16200.032
nervous system diseaseDOID:86300.027
Human
disease of anatomical entityDOID:700.027
Human
central nervous system diseaseDOID:33100.027
Human
organ system cancerDOID:005068600.024
neuropathyDOID:87000.013
disease of metabolismDOID:001466700.011