| carbohydrate metabolic process | GO:0005975 | 230 | 0.080 | |
| glycosylation | GO:0070085 | 62 | 0.079 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.078 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.068 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.064 | |
| glycoprotein biosynthetic process | GO:0009101 | 89 | 0.063 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.061 | |
| amine metabolic process | GO:0009308 | 45 | 0.059 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.055 | |
| sphingolipid metabolic process | GO:0006665 | 45 | 0.055 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.055 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.053 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.052 | |
| membrane lipid metabolic process | GO:0006643 | 53 | 0.051 | |
| protein localization to organelle | GO:0033365 | 185 | 0.051 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.049 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.049 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.048 | |
| endomembrane system organization | GO:0010256 | 147 | 0.045 | |
| spermatogenesis | GO:0007283 | 284 | 0.042 | |
| positive regulation of mitochondrial calcium ion concentration | GO:0051561 | 3 | 0.040 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.039 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.038 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.038 | |
| cellular homeostasis | GO:0019725 | 240 | 0.037 | |
| oxidation reduction process | GO:0055114 | 342 | 0.036 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.035 | |
| membrane lipid biosynthetic process | GO:0046467 | 32 | 0.035 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.035 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.034 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.033 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.033 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.032 | |
| regulation of ion transport | GO:0043269 | 215 | 0.032 | |
| protein catabolic process | GO:0030163 | 221 | 0.032 | |
| sphingolipid biosynthetic process | GO:0030148 | 26 | 0.031 | |
| cytokine production | GO:0001816 | 319 | 0.031 | |
| cation homeostasis | GO:0055080 | 212 | 0.030 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.029 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.029 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.029 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.028 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.027 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.027 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.026 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.026 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.026 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.026 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.026 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.025 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.025 | |
| regulation of protein localization | GO:0032880 | 231 | 0.025 | |
| vesicle localization | GO:0051648 | 86 | 0.025 | |
| inflammatory response | GO:0006954 | 244 | 0.025 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.025 | |
| transmembrane transport | GO:0055085 | 412 | 0.024 | |
| male gamete generation | GO:0048232 | 285 | 0.024 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.024 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.024 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.024 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.023 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.023 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.023 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.023 | |
| protein maturation | GO:0051604 | 176 | 0.023 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.022 | |
| regulation of protein transport | GO:0051223 | 163 | 0.022 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.022 | |
| response to inorganic substance | GO:0010035 | 96 | 0.022 | |
| positive regulation of interleukin 8 production | GO:0032757 | 2 | 0.022 | |
| interleukin 6 production | GO:0032635 | 58 | 0.021 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.021 | |
| cation transport | GO:0006812 | 399 | 0.021 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.021 | |
| retrograde transport endosome to golgi | GO:0042147 | 2 | 0.020 | |
| alcohol metabolic process | GO:0006066 | 116 | 0.020 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.020 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.020 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.020 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.020 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.020 | |
| protein processing | GO:0016485 | 163 | 0.020 | |
| regulation of secretion | GO:0051046 | 274 | 0.019 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.019 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.019 | |
| plasma membrane organization | GO:0007009 | 90 | 0.019 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.019 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.019 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.019 | |
| regulation of cell activation | GO:0050865 | 289 | 0.019 | |
| gland development | GO:0048732 | 330 | 0.019 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.019 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.019 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.019 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.019 | |
| protein localization to membrane | GO:0072657 | 108 | 0.018 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.018 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.018 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.018 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.018 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.018 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.018 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.018 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.018 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.018 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.018 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.018 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.018 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.018 | |
| regulation of binding | GO:0051098 | 111 | 0.017 | |
| interleukin 8 production | GO:0032637 | 4 | 0.017 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.017 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.017 | |
| immune effector process | GO:0002252 | 321 | 0.017 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.017 | |
| response to drug | GO:0042493 | 75 | 0.017 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.017 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.017 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.017 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.017 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.017 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.017 | |
| organelle localization | GO:0051640 | 179 | 0.016 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.016 | |
| protein ubiquitination | GO:0016567 | 171 | 0.016 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.016 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.016 | |
| protein glycosylation | GO:0006486 | 55 | 0.016 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.016 | |
| protein localization to plasma membrane | GO:0072659 | 57 | 0.016 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.016 | |
| intracellular protein transport | GO:0006886 | 204 | 0.016 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.016 | |
| neuron death | GO:0070997 | 154 | 0.016 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.016 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.016 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.016 | |
| peptidyl asparagine modification | GO:0018196 | 1 | 0.016 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.016 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.015 | |
| mapk cascade | GO:0000165 | 281 | 0.015 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.015 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 39 | 0.015 | |
| phospholipid biosynthetic process | GO:0008654 | 36 | 0.015 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.015 | |
| peptide secretion | GO:0002790 | 114 | 0.015 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.015 | |
| glucose homeostasis | GO:0042593 | 128 | 0.015 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.015 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 65 | 0.015 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.015 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.015 | |
| golgi vesicle transport | GO:0048193 | 30 | 0.015 | Human |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.015 | |
| glycerolipid biosynthetic process | GO:0045017 | 50 | 0.015 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.015 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.014 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.014 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.014 | |
| lateral inhibition | GO:0046331 | 1 | 0.014 | |
| cell division | GO:0051301 | 120 | 0.014 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.014 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.014 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.014 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.014 | |
| protein palmitoylation | GO:0018345 | 14 | 0.014 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.014 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.014 | |
| cellular amide metabolic process | GO:0043603 | 58 | 0.014 | |
| regulation of transporter activity | GO:0032409 | 57 | 0.014 | |
| exocytosis | GO:0006887 | 121 | 0.014 | |
| compound eye development | GO:0048749 | 1 | 0.014 | |
| central nervous system morphogenesis | GO:0021551 | 2 | 0.013 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.013 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.013 | |
| chromatin modification | GO:0016568 | 187 | 0.013 | |
| dephosphorylation | GO:0016311 | 129 | 0.013 | |
| ceramide metabolic process | GO:0006672 | 31 | 0.013 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.013 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.013 | |
| peptide hormone secretion | GO:0030072 | 109 | 0.013 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.013 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.013 | |
| lipoprotein metabolic process | GO:0042157 | 43 | 0.013 | |
| transition metal ion homeostasis | GO:0055076 | 54 | 0.013 | |
| adult behavior | GO:0030534 | 135 | 0.013 | |
| regulation of glutamate receptor signaling pathway | GO:1900449 | 16 | 0.013 | |
| amide transport | GO:0042886 | 138 | 0.013 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.013 | |
| early endosome to late endosome transport | GO:0045022 | 2 | 0.013 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.013 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.013 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.013 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.013 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 50 | 0.013 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.013 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.013 | |
| regulation of cell motility | GO:2000145 | 236 | 0.012 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.012 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.012 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.012 | |
| cellular modified amino acid biosynthetic process | GO:0042398 | 12 | 0.012 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.012 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.012 | |
| stem cell differentiation | GO:0048863 | 268 | 0.012 | |
| protein acylation | GO:0043543 | 64 | 0.012 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.012 | |
| membrane organization | GO:0061024 | 245 | 0.012 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.012 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.012 | |
| protein targeting | GO:0006605 | 143 | 0.012 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.012 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.012 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.012 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.012 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.012 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.012 | |
| hormone secretion | GO:0046879 | 128 | 0.012 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.012 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.012 | |
| regulation of neurotransmitter levels | GO:0001505 | 87 | 0.012 | |
| cellular response to lipid | GO:0071396 | 145 | 0.012 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.012 | |
| regulation of defense response | GO:0031347 | 233 | 0.011 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.011 | |
| regulation of receptor activity | GO:0010469 | 41 | 0.011 | |
| leukocyte migration | GO:0050900 | 124 | 0.011 | |
| second messenger mediated signaling | GO:0019932 | 73 | 0.011 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.011 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.011 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.011 | |
| response to acid chemical | GO:0001101 | 111 | 0.011 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.011 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.011 | |
| peptide transport | GO:0015833 | 133 | 0.011 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.011 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.011 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.011 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.011 | |
| regulation of tumor necrosis factor production | GO:0032680 | 49 | 0.011 | |
| nuclear transport | GO:0051169 | 139 | 0.011 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.011 | |
| pharynx development | GO:0060465 | 1 | 0.011 | |
| glycerophospholipid biosynthetic process | GO:0046474 | 32 | 0.011 | |
| synaptic transmission | GO:0007268 | 329 | 0.011 | |
| regulation of er to golgi vesicle mediated transport | GO:0060628 | 4 | 0.011 | |
| t cell activation | GO:0042110 | 289 | 0.011 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.011 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.011 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.011 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.011 | |
| trivalent inorganic cation transport | GO:0072512 | 5 | 0.011 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.011 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.011 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.010 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.010 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.010 | |
| organism emergence from protective structure | GO:0071684 | 4 | 0.010 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.010 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.010 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.010 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.010 | |
| nuclear division | GO:0000280 | 158 | 0.010 | |
| forebrain development | GO:0030900 | 302 | 0.010 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.010 | |
| sensory perception | GO:0007600 | 245 | 0.010 | |
| chromatin organization | GO:0006325 | 206 | 0.010 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.010 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.010 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.010 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.010 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.010 | |
| response to monosaccharide | GO:0034284 | 67 | 0.010 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.010 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.010 | |