IMP: Integrative Multi-species Prediction

Mus musculus

150 known processes

Carm1

coactivator-associated arginine methyltransferase 1

(Aliases: MGC46828,Prmt4)

Entrez: 59035
Ensembl: ENSMUSG00000032185
UniProtKB: Q9WVG6

Process Predictions
Disease Predictions

Carm1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
modification dependent protein catabolic process	GO:0019941	133	0.495
chromatin organization	GO:0006325	206	0.439
development of primary sexual characteristics	GO:0045137	143	0.392
protein catabolic process	GO:0030163	221	0.316
negative regulation of protein metabolic process	GO:0051248	282	0.306
leukocyte differentiation	GO:0002521	342	0.305
male gamete generation	GO:0048232	285	0.225
gland development	GO:0048732	330	0.225
dna metabolic process	GO:0006259	303	0.222
cellular macromolecule catabolic process	GO:0044265	206	0.216
proteasomal protein catabolic process	GO:0010498	98	0.208
protein ubiquitination	GO:0016567	171	0.189
histone acetylation	GO:0016573	41	0.166
peptidyl amino acid modification	GO:0018193	336	0.163
cellular protein catabolic process	GO:0044257	155	0.161
embryonic placenta development	GO:0001892	98	0.146
female sex differentiation	GO:0046660	84	0.141
epithelial tube morphogenesis	GO:0060562	303	0.136
wnt signaling pathway	GO:0016055	188	0.125
regulation of binding	GO:0051098	111	0.120
negative regulation of cellular protein metabolic process	GO:0032269	247	0.106
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.104
macromolecule catabolic process	GO:0009057	281	0.097
peptidyl lysine modification	GO:0018205	77	0.097
intracellular receptor signaling pathway	GO:0030522	74	0.096
histone h4 acetylation	GO:0043967	10	0.092
regulation of receptor activity	GO:0010469	41	0.090
protein modification by small protein conjugation or removal	GO:0070647	207	0.090
male sex differentiation	GO:0046661	109	0.090
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.088
positive regulation of receptor activity	GO:2000273	17	0.087
development of primary male sexual characteristics	GO:0046546	88	0.083
regulation of cell cycle process	GO:0010564	160	0.083
spermatogenesis	GO:0007283	284	0.082
placenta development	GO:0001890	140	0.081
cellular amino acid metabolic process	GO:0006520	103	0.077
modification dependent macromolecule catabolic process	GO:0043632	133	0.077
chromatin modification	GO:0016568	187	0.076
regulation of proteasomal protein catabolic process	GO:0061136	46	0.075
ubiquitin dependent protein catabolic process	GO:0006511	129	0.074
regulation of cellular protein catabolic process	GO:1903362	61	0.074
negative regulation of cell proliferation	GO:0008285	296	0.073
male gonad development	GO:0008584	88	0.071
regulation of wnt signaling pathway	GO:0030111	123	0.069
mammary gland epithelium development	GO:0061180	65	0.069
negative regulation of protein modification process	GO:0031400	163	0.068
female mating behavior	GO:0060180	8	0.067
regulation of female receptivity	GO:0045924	6	0.065
amine metabolic process	GO:0009308	45	0.064
purine nucleoside catabolic process	GO:0006152	205	0.064
cellular ketone metabolic process	GO:0042180	84	0.063
negative regulation of protein phosphorylation	GO:0001933	126	0.063
anatomical structure homeostasis	GO:0060249	145	0.061
multi multicellular organism process	GO:0044706	109	0.059
positive regulation of cell motility	GO:2000147	116	0.057
regulation of proteolysis	GO:0030162	164	0.056
gonad development	GO:0008406	141	0.055
negative regulation of kinase activity	GO:0033673	81	0.055
regulation of cellular catabolic process	GO:0031329	242	0.053
cellular amine metabolic process	GO:0044106	44	0.053
negative regulation of intracellular signal transduction	GO:1902532	167	0.051
hexose metabolic process	GO:0019318	98	0.051
negative regulation of transferase activity	GO:0051348	85	0.051
myeloid leukocyte differentiation	GO:0002573	119	0.050
sensory organ morphogenesis	GO:0090596	242	0.049
nucleobase containing small molecule metabolic process	GO:0055086	352	0.048
regulation of protein kinase activity	GO:0045859	232	0.047
regionalization	GO:0003002	337	0.046
positive regulation of protein modification process	GO:0031401	299	0.046
nucleocytoplasmic transport	GO:0006913	139	0.045
morphogenesis of a branching structure	GO:0001763	203	0.044
protein acylation	GO:0043543	64	0.043
carbon catabolite activation of transcription	GO:0045991	4	0.043
dephosphorylation	GO:0016311	129	0.042
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.041
internal peptidyl lysine acetylation	GO:0018393	42	0.041
positive regulation of protein phosphorylation	GO:0001934	242	0.040
digestive system development	GO:0055123	200	0.040
nucleotide metabolic process	GO:0009117	332	0.039
brain segmentation	GO:0035284	3	0.039
cytoplasmic transport	GO:0016482	234	0.039
morphogenesis of a branching epithelium	GO:0061138	193	0.039
positive regulation of wnt signaling pathway	GO:0030177	45	0.039
negative regulation of molecular function	GO:0044092	258	0.038
peptidyl lysine acetylation	GO:0018394	45	0.038
ribose phosphate metabolic process	GO:0019693	291	0.038
protein oligomerization	GO:0051259	67	0.038
myeloid cell differentiation	GO:0030099	233	0.038
regulation of apoptotic signaling pathway	GO:2001233	197	0.037
positive regulation of cell development	GO:0010720	237	0.036
ribonucleotide metabolic process	GO:0009259	291	0.036
protein polyubiquitination	GO:0000209	33	0.036
carbohydrate derivative catabolic process	GO:1901136	231	0.036
epithelial cell proliferation	GO:0050673	174	0.036
regulation of map kinase activity	GO:0043405	120	0.035
nuclear transport	GO:0051169	139	0.035
innate immune response	GO:0045087	157	0.035
organonitrogen compound biosynthetic process	GO:1901566	192	0.035
regulation of protein catabolic process	GO:0042176	108	0.035
internal protein amino acid acetylation	GO:0006475	42	0.035
protein modification by small protein conjugation	GO:0032446	187	0.034
nuclear import	GO:0051170	95	0.034
cell matrix adhesion	GO:0007160	68	0.034
stem cell differentiation	GO:0048863	268	0.033
regulation of protein serine threonine kinase activity	GO:0071900	157	0.033
rna interference	GO:0016246	2	0.033
regulation of transcription by galactose	GO:0000409	1	0.033
monosaccharide metabolic process	GO:0005996	106	0.033
primitive hemopoiesis	GO:0060215	7	0.032
purine ribonucleotide metabolic process	GO:0009150	290	0.032
embryonic organ morphogenesis	GO:0048562	276	0.032
compound eye development	GO:0048749	1	0.031
negative regulation of phosphorylation	GO:0042326	166	0.031
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.031
mammary gland duct morphogenesis	GO:0060603	38	0.031
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.031
branching morphogenesis of an epithelial tube	GO:0048754	159	0.031
cellular carbohydrate metabolic process	GO:0044262	119	0.030
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway	GO:0043162	3	0.030
methylation	GO:0032259	134	0.030
protein localization to nucleus	GO:0034504	121	0.029
regulation of muscle tissue development	GO:1901861	97	0.029	Zebrafish
covalent chromatin modification	GO:0016569	163	0.029
positive regulation of transcription by galactose	GO:0000411	1	0.029
renal system development	GO:0072001	225	0.029
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.029
sensory perception	GO:0007600	245	0.029
apoptotic signaling pathway	GO:0097190	306	0.029
regulation of kinase activity	GO:0043549	249	0.028
regulation of neuron differentiation	GO:0045664	281	0.028
mapk cascade	GO:0000165	281	0.028
regulation of cellular amino acid metabolic process	GO:0006521	5	0.027
g protein coupled receptor signaling pathway	GO:0007186	243	0.027
single organism nuclear import	GO:1902593	95	0.026
response to molecule of bacterial origin	GO:0002237	143	0.026
antimicrobial peptide production	GO:0002775	2	0.026
carbohydrate metabolic process	GO:0005975	230	0.025
regulation of cellular ketone metabolic process	GO:0010565	66	0.025
regulation of cytoplasmic transport	GO:1903649	112	0.025
regulation of interleukin 4 biosynthetic process	GO:0045402	3	0.025
response to drug	GO:0042493	75	0.025
developmental growth involved in morphogenesis	GO:0060560	138	0.025
dna methylation	GO:0006306	43	0.025
kidney development	GO:0001822	213	0.024
regulation of nucleotide catabolic process	GO:0030811	122	0.024
regulation of defense response	GO:0031347	233	0.024
rhythmic process	GO:0048511	174	0.024
small gtpase mediated signal transduction	GO:0007264	97	0.024
protein import into nucleus	GO:0006606	95	0.024
regulation of cell cycle	GO:0051726	281	0.024
regulation of nucleotide metabolic process	GO:0006140	169	0.023
muscle tissue development	GO:0060537	308	0.023	Zebrafish
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	40	0.023
carbon catabolite regulation of transcription	GO:0045990	4	0.023
purine ribonucleoside metabolic process	GO:0046128	241	0.023
regulation of response to drug	GO:2001023	2	0.023
regulation of fibroblast proliferation	GO:0048145	34	0.023
respiratory tube development	GO:0030323	167	0.023
negative regulation of phosphate metabolic process	GO:0045936	184	0.023
positive regulation of cell projection organization	GO:0031346	95	0.023
regulation of cellular amine metabolic process	GO:0033238	20	0.023
connective tissue development	GO:0061448	179	0.022
establishment of protein localization to organelle	GO:0072594	118	0.022
histone modification	GO:0016570	159	0.022
blood circulation	GO:0008015	195	0.021
glucose metabolic process	GO:0006006	92	0.021
positive regulation of neuron differentiation	GO:0045666	141	0.021
response to lipopolysaccharide	GO:0032496	128	0.021
genitalia development	GO:0048806	37	0.021
regulation of multi organism process	GO:0043900	111	0.021
cellular response to dna damage stimulus	GO:0006974	207	0.021
protein import	GO:0017038	101	0.021
homeostasis of number of cells	GO:0048872	210	0.021
striated muscle tissue development	GO:0014706	293	0.021	Zebrafish
regulation of chromosome organization	GO:0033044	83	0.021
digestive tract development	GO:0048565	190	0.020
response to organic cyclic compound	GO:0014070	198	0.020
cell growth	GO:0016049	130	0.020
calcium mediated signaling	GO:0019722	46	0.020
hematopoietic progenitor cell differentiation	GO:0002244	143	0.020
regulation of organelle organization	GO:0033043	289	0.020
positive regulation of organelle organization	GO:0010638	128	0.019
myotube differentiation	GO:0014902	105	0.019	Zebrafish
positive regulation of cellular amine metabolic process	GO:0033240	5	0.019
cellular response to organonitrogen compound	GO:0071417	145	0.019
cellular response to extracellular stimulus	GO:0031668	81	0.019
regulation of glucose metabolic process	GO:0010906	60	0.018
positive regulation of cytoplasmic transport	GO:1903651	40	0.018
negative regulation of map kinase activity	GO:0043407	34	0.018
cellular response to drug	GO:0035690	15	0.018
cell fate commitment	GO:0045165	210	0.018
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.018
thymus development	GO:0048538	41	0.018
metencephalon development	GO:0022037	89	0.018
skeletal system development	GO:0001501	356	0.018
ovarian follicle development	GO:0001541	40	0.018
actin cytoskeleton organization	GO:0030036	220	0.018
cellular response to growth factor stimulus	GO:0071363	197	0.018
dna dealkylation	GO:0035510	11	0.018
nucleoside triphosphate metabolic process	GO:0009141	230	0.018
regulation of transcription from rna polymerase ii promoter by galactose	GO:0000431	1	0.017
granulocyte differentiation	GO:0030851	17	0.017
regulation of ossification	GO:0030278	112	0.017
regulation of nucleocytoplasmic transport	GO:0046822	73	0.017
labyrinthine layer development	GO:0060711	49	0.017
embryonic hemopoiesis	GO:0035162	23	0.017
multicellular organism growth	GO:0035264	161	0.017
single organismal cell cell adhesion	GO:0016337	131	0.017
histone deubiquitination	GO:0016578	2	0.017
regulation of cytoskeleton organization	GO:0051493	122	0.017
regulation of epithelial cell proliferation	GO:0050678	141	0.017
lens development in camera type eye	GO:0002088	62	0.016
positive regulation of cellular catabolic process	GO:0031331	148	0.016
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.016
regulation of homeostatic process	GO:0032844	182	0.016
positive regulation of programmed cell death	GO:0043068	218	0.016
response to extracellular stimulus	GO:0009991	127	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.016
female gonad development	GO:0008585	71	0.016
regulation of antimicrobial peptide production	GO:0002784	1	0.016
development of primary female sexual characteristics	GO:0046545	73	0.016
multicellular organismal signaling	GO:0035637	91	0.016
regulation of transferase activity	GO:0051338	263	0.016
glycosyl compound metabolic process	GO:1901657	246	0.016
head morphogenesis	GO:0060323	34	0.016
immune response regulating signaling pathway	GO:0002764	125	0.016
lymphocyte differentiation	GO:0030098	242	0.016
regulation of cell motility	GO:2000145	236	0.016
positive regulation of cell death	GO:0010942	224	0.016
negative regulation of phosphorus metabolic process	GO:0010563	184	0.016
regulation of hydrolase activity	GO:0051336	246	0.016
demethylation	GO:0070988	23	0.015
regulation of cellular response to stress	GO:0080135	159	0.015
ribonucleoside catabolic process	GO:0042454	206	0.015
chemotaxis	GO:0006935	247	0.015
habituation	GO:0046959	3	0.015
immune effector process	GO:0002252	321	0.015
pharynx development	GO:0060465	1	0.015
intracellular steroid hormone receptor signaling pathway	GO:0030518	29	0.015
posttranscriptional regulation of gene expression	GO:0010608	155	0.015
cell maturation	GO:0048469	127	0.015
transmission of nerve impulse	GO:0019226	76	0.015
carbohydrate derivative biosynthetic process	GO:1901137	183	0.015
gene looping	GO:0090202	2	0.015
regulation of antimicrobial humoral response	GO:0002759	3	0.015
stem cell proliferation	GO:0072089	117	0.015
muscle system process	GO:0003012	141	0.014
spermatid development	GO:0007286	108	0.014
myeloid cell homeostasis	GO:0002262	114	0.014
female genitalia development	GO:0030540	14	0.014
regulation of purine nucleotide metabolic process	GO:1900542	169	0.014
vagina development	GO:0060068	11	0.014
dsdna loop formation	GO:0090579	2	0.014
antimicrobial peptide biosynthetic process	GO:0002777	2	0.014
fat cell differentiation	GO:0045444	160	0.014
nucleotide catabolic process	GO:0009166	217	0.014
ribonucleotide catabolic process	GO:0009261	208	0.014
cellular response to hormone stimulus	GO:0032870	150	0.014
zygotic determination of anterior posterior axis embryo	GO:0007354	3	0.014
cellular homeostasis	GO:0019725	240	0.014
negative regulation of growth	GO:0045926	99	0.014
synapse organization	GO:0050808	125	0.014
regulation of myeloid cell differentiation	GO:0045637	96	0.014
nucleoside phosphate metabolic process	GO:0006753	338	0.013
mitral valve development	GO:0003174	4	0.013
negative regulation of mrna processing	GO:0050686	12	0.013
response to nutrient levels	GO:0031667	109	0.013
negative regulation of mapk cascade	GO:0043409	65	0.013
purine ribonucleotide catabolic process	GO:0009154	208	0.013
regulation of protein import into nucleus	GO:0042306	52	0.013
extrinsic apoptotic signaling pathway	GO:0097191	126	0.013
tube formation	GO:0035148	140	0.013
activation of immune response	GO:0002253	138	0.013
regulation of translation	GO:0006417	71	0.013
cardiac muscle cell differentiation	GO:0055007	69	0.013
negative regulation of defense response	GO:0031348	77	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.013
negative regulation of cell cycle process	GO:0010948	69	0.013
genetic imprinting	GO:0071514	27	0.013
spermatid differentiation	GO:0048515	115	0.013
rap protein signal transduction	GO:0032486	3	0.013
purine containing compound metabolic process	GO:0072521	311	0.013
positive regulation of binding	GO:0051099	49	0.013
embryonic placenta morphogenesis	GO:0060669	25	0.013
organic cyclic compound catabolic process	GO:1901361	295	0.013
epithelial tube formation	GO:0072175	130	0.013
regulation of peptidyl lysine acetylation	GO:2000756	22	0.013
translation	GO:0006412	93	0.012
cation transport	GO:0006812	399	0.012
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.012
protein targeting	GO:0006605	143	0.012
b cell differentiation	GO:0030183	78	0.012
nucleoside catabolic process	GO:0009164	206	0.012
cell division	GO:0051301	120	0.012
positive regulation of transcription from rna polymerase ii promoter by galactose	GO:0000435	1	0.012
mesenchymal cell proliferation	GO:0010463	44	0.012
spleen development	GO:0048536	39	0.012
intracellular protein transport	GO:0006886	204	0.012
respiratory system development	GO:0060541	190	0.012
positive regulation of nucleotide metabolic process	GO:0045981	114	0.012
body morphogenesis	GO:0010171	45	0.012
mesoderm development	GO:0007498	100	0.012
cellular response to lipid	GO:0071396	145	0.012
calcium ion homeostasis	GO:0055074	127	0.012
cellular response to peptide hormone stimulus	GO:0071375	92	0.012
intrinsic apoptotic signaling pathway	GO:0097193	132	0.012
purine nucleoside metabolic process	GO:0042278	241	0.012
stem cell maintenance	GO:0019827	130	0.012
regulation of histone modification	GO:0031056	56	0.012
negative regulation of cellular catabolic process	GO:0031330	47	0.012
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.012
dna hypermethylation	GO:0044026	3	0.012
ossification	GO:0001503	216	0.012
cellular response to peptide	GO:1901653	92	0.012
development of secondary female sexual characteristics	GO:0046543	8	0.012
nucleotide biosynthetic process	GO:0009165	78	0.012
negative regulation of immune system process	GO:0002683	209	0.012
regulation of cell adhesion	GO:0030155	154	0.012
mammary gland morphogenesis	GO:0060443	54	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.012
skeletal muscle organ development	GO:0060538	163	0.012	Zebrafish
carbon catabolite activation of transcription from rna polymerase ii promoter	GO:0000436	4	0.012
chromosome separation	GO:0051304	14	0.011
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.011
biomineral tissue development	GO:0031214	64	0.011
locomotory behavior	GO:0007626	195	0.011
mitochondrion organization	GO:0007005	134	0.011
tissue homeostasis	GO:0001894	115	0.011
pole plasm assembly	GO:0007315	2	0.011
jak stat cascade	GO:0007259	42	0.011
neuroblast differentiation	GO:0014016	2	0.011
positive regulation of intracellular steroid hormone receptor signaling pathway	GO:0033145	4	0.011
neural tube closure	GO:0001843	90	0.011
second messenger mediated signaling	GO:0019932	73	0.011
primary neural tube formation	GO:0014020	95	0.011
regulation of cell cycle phase transition	GO:1901987	77	0.011
neuroblast fate determination	GO:0007400	1	0.011
adult locomotory behavior	GO:0008344	91	0.011
regulation of fat cell differentiation	GO:0045598	81	0.011
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.011
mesenchyme development	GO:0060485	152	0.011
nucleoside metabolic process	GO:0009116	246	0.011
learning	GO:0007612	98	0.011
negative regulation of tor signaling	GO:0032007	13	0.011
purine ribonucleoside catabolic process	GO:0046130	205	0.011
epithelial cell development	GO:0002064	159	0.011
cardiac muscle cell development	GO:0055013	39	0.011
striated muscle cell development	GO:0055002	125	0.011	Zebrafish
cerebellum development	GO:0021549	77	0.010
cell junction assembly	GO:0034329	52	0.010
negative regulation of proteolysis involved in cellular protein catabolic process	GO:1903051	22	0.010
aromatic compound catabolic process	GO:0019439	286	0.010
cellular response to abiotic stimulus	GO:0071214	56	0.010
regulation of protein ubiquitination	GO:0031396	52	0.010
nuclear division	GO:0000280	158	0.010
negative regulation of protein serine threonine kinase activity	GO:0071901	49	0.010
regulation of neuron apoptotic process	GO:0043523	122	0.010
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.010
positive regulation of proteolysis	GO:0045862	85	0.010
purine nucleotide metabolic process	GO:0006163	302	0.010
spindle checkpoint	GO:0031577	12	0.010
cell substrate adhesion	GO:0031589	130	0.010
muscle cell differentiation	GO:0042692	261	0.010	Zebrafish
maintenance of location	GO:0051235	89	0.010
response to organonitrogen compound	GO:0010243	246	0.010
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.010
t cell differentiation	GO:0030217	174	0.010
dna repair	GO:0006281	107	0.010

Carm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.028
	musculoskeletal system disease	DOID:17	0	0.028

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