Mus musculus

466 known processes

Lrp6

low density lipoprotein receptor-related protein 6

(Aliases: Gw,C030016K15Rik,Cd)

Lrp6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
formation of radial glial scaffoldsGO:002194340.999
axis elongation involved in somitogenesisGO:009024540.997
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.997
non canonical wnt signaling pathwayGO:0035567330.996
wnt signaling pathway involved in somitogenesisGO:009024440.994
endodermal cell fate specificationGO:000171440.992
embryonic organ morphogenesisGO:00485622760.991
regionalizationGO:00030023370.991
canonical wnt signaling pathway involved in heart developmentGO:006131630.988
neural tube developmentGO:00219151600.977
mammary placode formationGO:006059640.977
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.972
endodermal cell fate commitmentGO:0001711120.971
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.968
somitogenesisGO:0001756690.965
planar cell polarity pathway involved in heart morphogenesisGO:006134630.961
canonical wnt signaling pathwayGO:00600701300.959
embryonic heart tube morphogenesisGO:0003143510.955
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferationGO:006132420.953
regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016310.951
negative regulation of cardiac chamber morphogenesisGO:190122020.947
wnt signaling pathwayGO:00160551880.941
cardiac right atrium morphogenesisGO:000321330.932
genitalia morphogenesisGO:0035112110.930
cell proliferation involved in outflow tract morphogenesisGO:006132540.917
stem cell developmentGO:00488642190.916
Human Mouse
morphogenesis of a polarized epitheliumGO:0001738370.909
neural tube patterningGO:0021532430.900
regulation of wnt signaling pathwayGO:00301111230.893
planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:006134920.875
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.865
lung inductionGO:006049230.865
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:200015110.860
positive regulation of wnt signaling pathwayGO:0030177450.860
Human
gastrulationGO:00073691160.858
cardiac chamber developmentGO:00032051080.857
primary neural tube formationGO:0014020950.841
nodal signaling pathway involved in determination of left right asymmetryGO:003810720.841
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.840
trachea cartilage morphogenesisGO:006053540.835
digestive system developmentGO:00551232000.824
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.814
skeletal system developmentGO:00015013560.811
negative regulation of cell growth involved in cardiac muscle cell developmentGO:006105220.796
embryonic skeletal system developmentGO:00487061200.795
single organismal cell cell adhesionGO:00163371310.788
branching morphogenesis of an epithelial tubeGO:00487541590.776
forebrain neuroblast divisionGO:002187390.768
digestive tract developmentGO:00485651900.767
planar cell polarity pathway involved in ventricular septum morphogenesisGO:006134820.760
neural tube formationGO:00018411080.756
heart field specificationGO:000312860.753
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016420.753
segmentationGO:0035282930.749
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.745
planar cell polarity pathway involved in outflow tract morphogenesisGO:006134720.741
somite developmentGO:0061053810.737
regulation of cardiac chamber morphogenesisGO:190121920.736
negative regulation of protein modification processGO:00314001630.734
Human
stem cell differentiationGO:00488632680.731
branching involved in mammary gland duct morphogenesisGO:0060444270.730
embryonic skeletal joint developmentGO:0072498130.726
stem cell proliferationGO:00720891170.717
epithelial tube morphogenesisGO:00605623030.716
negative regulation of planar cell polarity pathway involved in heart morphogenesisGO:200016010.715
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009420.714
regulation of endodermal cell fate specificationGO:004266320.710
negative regulation of phosphorus metabolic processGO:00105631840.708
Human
morphogenesis of embryonic epitheliumGO:00163311590.702
neural tube closureGO:0001843900.701
negative regulation of cell proliferationGO:00082852960.701
rostrocaudal neural tube patterningGO:0021903120.699
chondrocyte differentiationGO:0002062720.698
nephrogenic mesenchyme morphogenesisGO:007213420.685
negative regulation of mesenchymal cell proliferationGO:007220130.680
cardiac septum morphogenesisGO:0060411460.675
positive regulation of mesenchymal cell proliferationGO:0002053330.670
muscle tissue developmentGO:00605373080.666
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016410.659
osteoblast developmentGO:0002076170.658
Mouse
negative regulation of cell fate specificationGO:000999640.655
hindbrain developmentGO:00309021280.653
cell adhesionGO:00071553290.650
neural plate developmentGO:0001840120.647
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016210.645
post anal tail morphogenesisGO:0036342230.644
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014910.643
cerebral cortex developmentGO:0021987860.643
mesenchyme developmentGO:00604851520.638
neuroblast divisionGO:0055057100.630
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.630
Mouse
ventricular septum morphogenesisGO:0060412270.624
regulation of wnt signaling pathway planar cell polarity pathwayGO:2000095100.624
wnt signaling pathway planar cell polarity pathwayGO:0060071270.614
establishment of planar polarity involved in neural tube closureGO:0090177150.613
neuron projection guidanceGO:00974851410.610
convergent extensionGO:0060026140.601
morphogenesis of a branching structureGO:00017632030.600
hypermethylation of cpg islandGO:004402730.598
cellular macromolecule catabolic processGO:00442652060.598
Mouse
dna metabolic processGO:00062593030.593
determination of left right symmetryGO:0007368800.592
cardiac muscle tissue morphogenesisGO:0055008440.591
negative regulation of neuron differentiationGO:00456651010.583
Mouse
cell migration involved in gastrulationGO:0042074130.582
forebrain generation of neuronsGO:0021872630.579
respiratory tube developmentGO:00303231670.574
embryonic appendage morphogenesisGO:00351131260.574
respiratory system developmentGO:00605411900.573
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007203940.572
epithelial to mesenchymal transitionGO:0001837470.571
Human
foregut regionalizationGO:006042330.569
cardiac ventricle developmentGO:0003231830.569
muscle system processGO:00030121410.569
somite specificationGO:000175740.567
regulation of canonical wnt signaling pathwayGO:0060828820.566
Human
cardiac endothelial cell differentiationGO:000334840.561
appendage morphogenesisGO:00351071490.560
regulation of planar cell polarity pathway involved in heart morphogenesisGO:200015910.559
mesenchymal cell differentiationGO:00487621070.558
renal system developmentGO:00720012250.552
Mouse
regulation of skeletal muscle fiber differentiationGO:190280930.552
odontogenesisGO:0042476780.552
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200006080.547
Mouse
blood circulationGO:00080151950.546
regulation of neuron differentiationGO:00456642810.545
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.535
regulation of mesenchymal cell proliferationGO:0010464370.532
sensory organ morphogenesisGO:00905962420.531
regulation of fat cell differentiationGO:0045598810.530
embryonic camera type eye developmentGO:0031076360.528
chondrocyte developmentGO:0002063240.524
digestive tract morphogenesisGO:00485461470.524
cellular amine metabolic processGO:0044106440.524
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.523
mammary gland epithelium developmentGO:0061180650.523
establishment of tissue polarityGO:0007164280.522
metanephric mesenchyme morphogenesisGO:007213340.520
urogenital system developmentGO:00016552610.514
Mouse
cellular amino acid metabolic processGO:00065201030.513
embryonic digit morphogenesisGO:0042733560.511
mesenchymal cell proliferationGO:0010463440.507
forebrain developmentGO:00309003020.504
stem cell maintenanceGO:00198271300.503
Mouse
cardiac muscle tissue developmentGO:00487381300.502
positive regulation of branching involved in lung morphogenesisGO:006104740.501
renal vesicle inductionGO:007203430.501
negative regulation of planar cell polarity pathway involved in neural tube closureGO:200016810.500
negative regulation of hormone biosynthetic processGO:003235340.498
hindlimb morphogenesisGO:0035137420.497
cell migration in hindbrainGO:0021535160.496
purine containing compound catabolic processGO:00725232130.495
pallium developmentGO:00215431200.492
regulation of heart morphogenesisGO:2000826220.487
negative regulation of protein phosphorylationGO:00019331260.486
Human
polarity specification of proximal distal axisGO:001008520.485
regulation of cellular amino acid metabolic processGO:000652150.484
telencephalon developmentGO:00215371860.481
axial mesodermal cell fate commitmentGO:004832210.481
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016110.480
axis elongationGO:0003401300.478
cardiac left ventricle morphogenesisGO:000321490.477
regulation of cellular protein catabolic processGO:1903362610.476
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.474
telencephalon cell migrationGO:0022029550.472
cell proliferation in hindbrainGO:0021534100.471
Mouse
renal inner medulla developmentGO:007205330.471
endocardial cushion formationGO:0003272130.464
endoderm formationGO:0001706200.463
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103060.459
determination of heart left right asymmetryGO:0061371480.457
regulation of phospholipase activityGO:001051790.456
Mouse
negative regulation of platelet derived growth factor receptor beta signaling pathwayGO:200058720.449
Mouse
cellular ketone metabolic processGO:0042180840.446
regulation of cellular amine metabolic processGO:0033238200.444
mesodermal cell migrationGO:000807840.439
negative regulation of cell developmentGO:00107211690.438
Mouse
lung developmentGO:00303241640.437
negative regulation of cell projection organizationGO:0031345560.437
Mouse
ear developmentGO:00435832000.437
regulation of cardiac muscle tissue developmentGO:0055024310.437
regulation of mapk cascadeGO:00434082480.434
Mouse
axon guidanceGO:00074111410.431
central nervous system morphogenesisGO:002155120.430
establishment of planar polarity of embryonic epitheliumGO:0042249160.428
embryonic limb morphogenesisGO:00303261260.424
sinoatrial node cell differentiationGO:006092130.422
positive regulation of proteolysisGO:0045862850.417
Mouse
heart morphogenesisGO:00030071780.415
embryonic skeletal system morphogenesisGO:0048704910.412
hindbrain radial glia guided cell migrationGO:0021932120.408
hexose metabolic processGO:0019318980.395
midbrain hindbrain boundary developmentGO:003091790.392
midbrain hindbrain boundary morphogenesisGO:002155540.390
multicellular organismal homeostasisGO:00488711640.390
mesoderm developmentGO:00074981000.388
negative regulation of neuron projection developmentGO:0010977500.380
Mouse
regulation of establishment of planar polarityGO:0090175280.379
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122840.375
regulation of cell morphogenesis involved in differentiationGO:00107691510.374
Mouse
cardiac cell fate specificationGO:006091220.373
mesenchymal cell developmentGO:0014031930.372
Human
pericardium morphogenesisGO:000334450.372
negative regulation of wnt signaling pathwayGO:0030178730.370
cardiac chamber morphogenesisGO:0003206930.369
aorta morphogenesisGO:0035909220.369
Mouse
carbohydrate metabolic processGO:00059752300.368
negative regulation of cardiac muscle tissue developmentGO:005502680.367
positive regulation of hh target transcription factor activityGO:000722830.365
central nervous system vasculogenesisGO:002200930.364
ossificationGO:00015032160.364
negative regulation of cholesterol transportGO:003237540.363
Mouse
ventricular zone neuroblast divisionGO:002184730.361
cerebellum developmentGO:0021549770.360
neural crest cell differentiationGO:0014033540.359
mesodermal to mesenchymal transition involved in gastrulationGO:006080910.357
nephric duct formationGO:007217940.356
regulation of muscle tissue developmentGO:1901861970.355
cell fate specificationGO:0001708720.354
regulation of planar cell polarity pathway involved in neural tube closureGO:200016710.354
epithelial tube formationGO:00721751300.353
proteolysis involved in cellular protein catabolic processGO:00516031470.353
Mouse
skeletal system morphogenesisGO:00487052030.352
peptidyl amino acid modificationGO:00181933360.352
Mouse
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.352
positive regulation of ossificationGO:0045778470.351
cartilage developmentGO:00512161400.346
organic hydroxy compound metabolic processGO:19016152030.344
Mouse
endoderm developmentGO:0007492450.344
regulation of endodermal cell differentiationGO:190322420.344
establishment of endothelial blood brain barrierGO:001404530.342
embryonic skeletal joint morphogenesisGO:0060272110.342
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart developmentGO:006131010.341
regulation of proteolysisGO:00301621640.341
Mouse
ear morphogenesisGO:00424711180.337
regulation of protein serine threonine kinase activityGO:00719001570.336
Human Mouse
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:200015010.335
limb morphogenesisGO:00351081490.335
lung field specificationGO:006042430.335
negative regulation of cellular amine metabolic processGO:003323910.333
positive regulation of nuclear divisionGO:0051785270.333
neuroblast differentiationGO:001401620.332
mammary gland formationGO:006059290.331
mesenchymal cell apoptotic process involved in nephron morphogenesisGO:190114540.331
negative regulation of sterol transportGO:003237240.331
Mouse
positive regulation of cellular protein catabolic processGO:1903364340.329
Mouse
camera type eye developmentGO:00430102660.329
negative regulation of nfat protein import into nucleusGO:005153430.328
purine ribonucleotide metabolic processGO:00091502900.326
organic cyclic compound catabolic processGO:19013612950.326
spermatogenesisGO:00072832840.326
cellular nitrogen compound catabolic processGO:00442702800.324
organ growthGO:00352651170.320
embryonic genitalia morphogenesisGO:003053840.318
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.316
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.314
morphogenesis of an epithelial sheetGO:0002011270.314
ectodermal placode formationGO:0060788160.311
purine ribonucleoside triphosphate metabolic processGO:00092052200.310
axial mesoderm formationGO:004832030.306
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.305
amine metabolic processGO:0009308450.302
purine nucleotide metabolic processGO:00061633020.301
germ line stem cell divisionGO:004207820.299
negative regulation of protein metabolic processGO:00512482820.299
Human
regulation of peptidyl threonine phosphorylationGO:0010799120.295
developmental growth involved in morphogenesisGO:00605601380.294
regulation of organelle organizationGO:00330432890.292
Mouse
regulation of cardiac chamber formationGO:190121010.292
atrioventricular bundle cell differentiationGO:000316710.291
negative regulation of molecular functionGO:00440922580.291
Human
embryonic epithelial tube formationGO:00018381300.285
vagus nerve morphogenesisGO:002164420.284
regulation of neuron maturationGO:001404150.283
ectodermal placode developmentGO:0071696160.280
engulfment of apoptotic cellGO:004365230.280
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082910.279
cerebellar granule cell precursor proliferationGO:0021930100.279
Mouse
chemotaxisGO:00069352470.278
positive regulation of cellular amino acid metabolic processGO:004576430.278
smoothened signaling pathway involved in dorsal ventral neural tube patterningGO:0060831120.277
semicircular canal developmentGO:006087290.276
formation of primary germ layerGO:0001704770.275
regulation of mitotic cell cycleGO:00073461260.274
endodermal cell differentiationGO:0035987140.274
regulation of cell cycle processGO:00105641600.273
limb developmentGO:00601731660.273
regulation of smoothened signaling pathwayGO:0008589580.271
glial cell differentiationGO:00100011310.270
negative regulation of alcohol biosynthetic processGO:190293140.269
retina vasculature development in camera type eyeGO:0061298170.268
Mouse
regulation of cardioblast differentiationGO:005189030.264
regulation of phospholipase a2 activityGO:003242930.263
Mouse
regulation of cell migrationGO:00303342190.258
Mouse
mesonephric epithelium developmentGO:0072163940.256
striated muscle tissue developmentGO:00147062930.255
cellular response to extracellular stimulusGO:0031668810.255
ventricular septum developmentGO:0003281420.255
renal outer medulla developmentGO:007205420.254
morphogenesis of an epithelial budGO:0060572180.251
negative regulation of osteoblast differentiationGO:0045668300.251
cerebellar granule cell differentiationGO:002170790.251
metencephalon developmentGO:0022037890.250
metanephric loop of henle developmentGO:007223640.250
regulation of purine nucleotide metabolic processGO:19005421690.248
neural crest cell migrationGO:0001755320.248
epithelial cell morphogenesisGO:0003382410.248
regulation of cellular component biogenesisGO:00440871810.246
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transportGO:009011810.244
mesoderm morphogenesisGO:0048332640.243
meiotic cell cycleGO:00513211220.243
regulation of tongue muscle cell differentiationGO:200103520.242
positive regulation of gtp catabolic processGO:0033126850.242
dorsal ventral neural tube patterningGO:0021904280.240
heparan sulfate proteoglycan biosynthetic processGO:001501280.239
lateral line system developmentGO:004892510.238
response to extracellular stimulusGO:00099911270.237
negative regulation of epidermis developmentGO:004568390.237
anatomical structure regressionGO:006003390.237
Mouse
regulation of osteoblast proliferationGO:0033688150.236
Mouse
bone morphogenesisGO:0060349780.236
synaptic growth at neuromuscular junctionGO:005112460.234
Mouse
thyroid stimulating hormone secreting cell differentiationGO:006012940.234
artery developmentGO:0060840530.233
Mouse
regulation of cytoskeleton organizationGO:00514931220.233
Mouse
regulation of cardiac cell fate specificationGO:200004310.232
notochord formationGO:001402850.232
anterior commissure morphogenesisGO:002196060.232
bone developmentGO:00603481200.231
positive regulation of tongue muscle cell differentiationGO:200103720.230
hair follicle developmentGO:0001942850.230
Mouse
negative regulation of jun kinase activityGO:004350890.230
purine nucleoside triphosphate metabolic processGO:00091442260.230
spinal cord motor neuron differentiationGO:0021522350.230
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.230
positive regulation of secondary heart field cardioblast proliferationGO:007251340.229
negative regulation of prostatic bud formationGO:006068640.229
regulation of presynaptic membrane organizationGO:190162930.229
Mouse
cell growth involved in cardiac muscle cell developmentGO:006104930.226
negative regulation of bmp signaling pathwayGO:0030514350.226
response to organic cyclic compoundGO:00140701980.226
neuron maturationGO:0042551290.225
specification of organ identityGO:0010092300.224
regulation of ras protein signal transductionGO:00465781140.224
negative regulation of lipid metabolic processGO:0045833300.224
forebrain cell migrationGO:0021885580.224
central nervous system neuron differentiationGO:00219531620.223
tooth mineralizationGO:003450590.223
external genitalia morphogenesisGO:003526110.222
monosaccharide metabolic processGO:00059961060.221
modification dependent macromolecule catabolic processGO:00436321330.220
Mouse
floor plate morphogenesisGO:003350530.220
axonogenesisGO:00074092740.220
Mouse
regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016510.220
muscle contractionGO:00069361010.219
regulation of heart inductionGO:009038120.219
midbrain hindbrain boundary maturationGO:002173210.219
ameboidal type cell migrationGO:00016671280.218
middle ear morphogenesisGO:0042474230.217
regulation of rho gtpase activityGO:0032319580.217
forebrain radial glial cell differentiationGO:002186140.216
glycosyl compound metabolic processGO:19016572460.215
physiological cardiac muscle hypertrophyGO:000330130.215
mitotic cell cycle processGO:19030471590.214
pituitary gland developmentGO:0021983380.214
neural plate morphogenesisGO:000183990.213
regulation of nucleotide metabolic processGO:00061401690.213
regulation of purine nucleotide catabolic processGO:00331211220.213
anatomical structure homeostasisGO:00602491450.213
circulatory system processGO:00030131970.213
cytoplasmic transportGO:00164822340.212
Mouse Fly
habituationGO:004695930.211
jnk cascadeGO:0007254720.210
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.210
brain morphogenesisGO:0048854320.209
small gtpase mediated signal transductionGO:0007264970.207
mesenchymal cell proliferation involved in ureter developmentGO:007219840.206
negative regulation of protein serine threonine kinase activityGO:0071901490.205
Human
regulation of stem cell proliferationGO:0072091780.205
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007204040.204
kidney mesenchyme morphogenesisGO:007213140.203
sulfur compound biosynthetic processGO:0044272370.202
positive regulation of canonical wnt signaling pathwayGO:0090263290.202
Human
heart inductionGO:000312920.201
schwann cell proliferationGO:001401020.201
heterocycle catabolic processGO:00467002800.199
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.198
Mouse
inner ear morphogenesisGO:00424721010.198
positive regulation of bindingGO:0051099490.197
Mouse
carbohydrate homeostasisGO:00335001280.196
Mouse
notch signaling pathwayGO:0007219710.195
regulation of ras gtpase activityGO:0032318880.195
nucleoside catabolic processGO:00091642060.195
cell proliferation in forebrainGO:0021846300.195
vagus nerve developmentGO:002156430.194
negative regulation of phosphorylationGO:00423261660.194
Human
forelimb morphogenesisGO:0035136400.193
negative regulation of cardiac muscle cell differentiationGO:200072620.193
positive regulation of cellular catabolic processGO:00313311480.193
Mouse
ubiquitin dependent protein catabolic processGO:00065111290.193
Mouse
skeletal muscle organ developmentGO:00605381630.192
positive regulation of cell deathGO:00109422240.192
purine nucleoside metabolic processGO:00422782410.192
regulation of heart loopingGO:190120710.191
positive regulation of mesenchymal cell proliferation involved in ureter developmentGO:200072930.191
establishment of protein localization to organelleGO:00725941180.190
Mouse Fly
trachea formationGO:006044030.190
face morphogenesisGO:0060325290.189
positive regulation of smoothened signaling pathwayGO:0045880230.188
regulation of cell cycleGO:00517262810.188
Human
cerebellum morphogenesisGO:0021587420.187
nucleoside metabolic processGO:00091162460.185
apoptotic process in bone marrowGO:007183910.184
positive regulation of cell divisionGO:0051781310.182
establishment of planar polarityGO:0001736280.182
pulmonary valve formationGO:000319310.181
embryonic eye morphogenesisGO:0048048290.181
cell fate commitmentGO:00451652100.181
microtubule based processGO:00070172360.181
kidney morphogenesisGO:0060993830.180
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082310.178
response to retinoic acidGO:0032526560.177
protein localization to membraneGO:00726571080.176
Mouse
regulation of hydrolase activityGO:00513362460.176
Mouse
regulation of mesenchymal cell proliferation involved in ureter developmentGO:007219930.176
regulation of lipase activityGO:0060191150.175
Mouse
embryonic heart tube developmentGO:0035050650.174
cell surface receptor signaling pathway involved in heart developmentGO:0061311150.173
limbic system developmentGO:0021761720.173
regulation of kinase activityGO:00435492490.172
Human Mouse
embryonic hindlimb morphogenesisGO:0035116320.172
negative regulation of striated muscle cell differentiationGO:0051154140.172
cerebral cortex neuron differentiationGO:0021895190.171
regulation of cell proliferation involved in outflow tract morphogenesisGO:190196320.171
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.171
regulation of osteoblast differentiationGO:0045667670.171
cardiac left ventricle formationGO:000321810.171
nucleotide metabolic processGO:00091173320.171
response to fibroblast growth factorGO:0071774470.170
neural crest cell migration involved in autonomic nervous system developmentGO:190116650.170
exocrine system developmentGO:0035272450.169
macromolecule catabolic processGO:00090572810.167
Mouse
regulation of ketone biosynthetic processGO:001056620.166
inner medullary collecting duct developmentGO:007206120.165
purine containing compound metabolic processGO:00725213110.165
mesonephric duct morphogenesisGO:007218040.164
regulation of striated muscle cell differentiationGO:0051153810.163
organelle localizationGO:00516401790.163
regulation of stem cell differentiationGO:2000736500.163
single organism cell adhesionGO:00986021560.163
gtp catabolic processGO:00061841430.163
negative regulation of cardiac chamber formationGO:190121110.162
mesonephric tubule developmentGO:0072164940.162
odontogenesis of dentin containing toothGO:0042475660.162
positive regulation of nervous system developmentGO:00519622210.162
Mouse
regulation of intracellular protein transportGO:0033157820.161
establishment of organelle localizationGO:00516561220.161
lateral inhibitionGO:004633110.159
blastocyst developmentGO:0001824800.159
positive regulation of cell cycleGO:0045787920.159
Human
protein ubiquitinationGO:00165671710.159
Mouse
regulation of cellular catabolic processGO:00313292420.159
Mouse
response to growth factorGO:00708481980.158
regulation of bmp signaling pathwayGO:0030510600.158
cell differentiation in hindbrainGO:0021533240.156
cerebellar granular layer developmentGO:0021681130.156
regulation of nucleotide catabolic processGO:00308111220.156
histone acetylationGO:0016573410.155
endodermal cell fate determinationGO:000749320.155
regulation of neuron projection developmentGO:00109751690.154
Mouse
synapse organizationGO:00508081250.153
Mouse
visceral motor neuron differentiationGO:002152430.153
regulation of platelet derived growth factor receptor beta signaling pathwayGO:200058620.153
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.153
regulation of cell proliferation involved in heart morphogenesisGO:2000136150.153
regulation of mesodermal cell fate specificationGO:004266150.152
hindbrain morphogenesisGO:0021575460.151
mammary gland bud morphogenesisGO:006064840.151
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.150
protein localization to organelleGO:00333651850.150
Mouse Fly
ribonucleotide metabolic processGO:00092592910.150
branching involved in ureteric bud morphogenesisGO:0001658560.149
positive regulation of heart growthGO:0060421180.149
midgut developmentGO:000749440.148
inner ear receptor cell differentiationGO:0060113610.147
trachea gland developmentGO:006115330.147
microtubule cytoskeleton organizationGO:00002261570.146
protein catabolic processGO:00301632210.146
Mouse
positive regulation of apoptotic processGO:00430652170.146

Lrp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.740
musculoskeletal system diseaseDOID:1700.740
connective tissue diseaseDOID:6500.740
bone diseaseDOID:008000100.450
sensory system diseaseDOID:005015500.392
nervous system diseaseDOID:86300.392
eye and adnexa diseaseDOID:149200.150
eye diseaseDOID:561400.150