Mus musculus

0 known processes

Klhl28

kelch-like 28 (Drosophila)

(Aliases: Btbd5,MGC47075,4931401E10Rik,2810440N09Rik,4122402F11Rik)

Klhl28 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular ketone metabolic processGO:0010565660.054
positive regulation of cellular amine metabolic processGO:003324050.049
modification dependent protein catabolic processGO:00199411330.049
small gtpase mediated signal transductionGO:0007264970.047
ras protein signal transductionGO:0007265770.047
cellular amino acid metabolic processGO:00065201030.044
protein modification by small protein conjugation or removalGO:00706472070.044
positive regulation of cellular amino acid metabolic processGO:004576430.040
carbohydrate metabolic processGO:00059752300.039
covalent chromatin modificationGO:00165691630.037
cellular macromolecule catabolic processGO:00442652060.036
male gamete generationGO:00482322850.035
Mouse
protein modification by small protein conjugationGO:00324461870.035
spermatogenesisGO:00072832840.035
Mouse
methylationGO:00322591340.032
regulation of cellular amine metabolic processGO:0033238200.032
cellular ketone metabolic processGO:0042180840.032
macromolecule catabolic processGO:00090572810.031
regulation of cellular amino acid metabolic processGO:000652150.030
purine ribonucleotide metabolic processGO:00091502900.030
heart morphogenesisGO:00030071780.028
protein ubiquitinationGO:00165671710.028
forebrain developmentGO:00309003020.028
cellular homeostasisGO:00197252400.028
homeostasis of number of cellsGO:00488722100.028
Mouse
cellular protein catabolic processGO:00442571550.027
regulation of cell motilityGO:20001452360.027
epithelial cell developmentGO:00020641590.027
dna metabolic processGO:00062593030.027
camera type eye developmentGO:00430102660.027
ubiquitin dependent protein catabolic processGO:00065111290.026
modification dependent macromolecule catabolic processGO:00436321330.026
amine metabolic processGO:0009308450.026
myeloid cell differentiationGO:00300992330.025
aromatic compound catabolic processGO:00194392860.025
cellular amine metabolic processGO:0044106440.025
immune effector processGO:00022523210.025
rho protein signal transductionGO:0007266320.025
histone modificationGO:00165701590.024
peptidyl amino acid modificationGO:00181933360.024
nucleoside metabolic processGO:00091162460.024
chromatin modificationGO:00165681870.023
microtubule based processGO:00070172360.023
positive regulation of protein modification processGO:00314012990.023
regulation of nucleotide metabolic processGO:00061401690.023
cellular response to dna damage stimulusGO:00069742070.022
cellular nitrogen compound catabolic processGO:00442702800.022
ribose phosphate metabolic processGO:00196932910.022
negative regulation of cellular component organizationGO:00511291940.022
oxidation reduction processGO:00551143420.022
protein catabolic processGO:00301632210.022
nucleoside phosphate metabolic processGO:00067533380.022
transmembrane transportGO:00550854120.022
organelle localizationGO:00516401790.022
sensory organ morphogenesisGO:00905962420.021
cation transportGO:00068123990.021
muscle system processGO:00030121410.021
gland developmentGO:00487323300.021
microtubule cytoskeleton organizationGO:00002261570.021
macromolecule methylationGO:00434141200.021
organonitrogen compound catabolic processGO:19015652640.021
response to acid chemicalGO:00011011110.021
dephosphorylationGO:00163111290.021
cell type specific apoptotic processGO:00972852680.021
response to organic cyclic compoundGO:00140701980.021
mapk cascadeGO:00001652810.020
negative regulation of molecular functionGO:00440922580.020
purine nucleotide metabolic processGO:00061633020.020
cytoplasmic transportGO:00164822340.020
heterocycle catabolic processGO:00467002800.020
regulation of cell migrationGO:00303342190.019
negative regulation of protein metabolic processGO:00512482820.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
regulation of organelle organizationGO:00330432890.019
negative regulation of cellular protein metabolic processGO:00322692470.019
nucleotide metabolic processGO:00091173320.019
regulation of cell projection organizationGO:00313442060.019
regulation of transferase activityGO:00513382630.019
lateral line system developmentGO:004892510.018
metal ion homeostasisGO:00550651890.018
organic cyclic compound catabolic processGO:19013612950.018
regulation of body fluid levelsGO:00508781620.018
leukocyte differentiationGO:00025213420.018
purine ribonucleotide catabolic processGO:00091542080.018
regulation of hydrolase activityGO:00513362460.018
endomembrane system organizationGO:00102561470.018
purine nucleotide catabolic processGO:00061952110.017
ribonucleoside triphosphate metabolic processGO:00091992200.017
cellular chemical homeostasisGO:00550822150.017
angiogenesisGO:00015252010.017
positive regulation of mapk cascadeGO:00434101700.017
nucleoside triphosphate metabolic processGO:00091412300.017
wound healingGO:00420601570.017
organelle fissionGO:00482851700.017
regulation of apoptotic signaling pathwayGO:20012331970.017
Mouse
response to radiationGO:00093141650.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
regulation of cellular response to stressGO:00801351590.017
cellular response to hormone stimulusGO:00328701500.017
regulation of anatomical structure sizeGO:00900661780.017
purine containing compound metabolic processGO:00725213110.017
regulation of cell adhesionGO:00301551540.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
response to growth factorGO:00708481980.017
nucleoside triphosphate catabolic processGO:00091432050.016
nucleoside phosphate catabolic processGO:19012922220.016
divalent inorganic cation transportGO:00725111780.016
purine nucleoside metabolic processGO:00422782410.016
cation homeostasisGO:00550802120.016
germ cell developmentGO:00072811850.016
Mouse
maintenance of locationGO:0051235890.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
carbohydrate derivative biosynthetic processGO:19011371830.016
ribonucleoside metabolic processGO:00091192450.016
divalent inorganic cation homeostasisGO:00725071380.016
glycosyl compound metabolic processGO:19016572460.016
actin filament organizationGO:00070151130.016
hematopoietic progenitor cell differentiationGO:00022441430.016
g protein coupled receptor signaling pathwayGO:00071862430.016
locomotory behaviorGO:00076261950.016
Mouse
negative regulation of phosphorylationGO:00423261660.016
ribonucleotide metabolic processGO:00092592910.016
establishment or maintenance of cytoskeleton polarityGO:003095220.016
nucleotide catabolic processGO:00091662170.016
actin cytoskeleton organizationGO:00300362200.016
regulation of ion transportGO:00432692150.016
negative regulation of intracellular signal transductionGO:19025321670.016
Mouse
epithelial tube morphogenesisGO:00605623030.015
renal system developmentGO:00720012250.015
calcium ion homeostasisGO:00550741270.015
endocytosisGO:00068971680.015
developmental maturationGO:00217001930.015
nucleobase containing small molecule metabolic processGO:00550863520.015
nuclear divisionGO:00002801580.015
synaptic transmissionGO:00072683290.015
cellular response to organonitrogen compoundGO:00714171450.015
organonitrogen compound biosynthetic processGO:19015661920.015
chromatin organizationGO:00063252060.015
apoptotic signaling pathwayGO:00971903060.015
Mouse
purine ribonucleoside metabolic processGO:00461282410.015
sensory system developmentGO:004888030.015
nitrogen compound transportGO:00717052710.015
ribonucleoside catabolic processGO:00424542060.015
negative regulation of organelle organizationGO:0010639900.015
cellular ion homeostasisGO:00068731650.015
positive regulation of nervous system developmentGO:00519622210.015
developmental growth involved in morphogenesisGO:00605601380.015
circulatory system processGO:00030131970.015
regulation of cellular catabolic processGO:00313292420.015
neuron deathGO:00709971540.015
regulation of ras protein signal transductionGO:00465781140.015
guanosine containing compound catabolic processGO:19010691440.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.014
divalent metal ion transportGO:00708381720.014
ameboidal type cell migrationGO:00016671280.014
multicellular organism growthGO:00352641610.014
regulation of lymphocyte activationGO:00512492400.014
regulation of mapk cascadeGO:00434082480.014
cell substrate adhesionGO:00315891300.014
dna modificationGO:0006304500.014
regulation of cellular component sizeGO:00325351210.014
retrograde transport endosome to golgiGO:004214720.014
telencephalon developmentGO:00215371860.014
cellular protein complex assemblyGO:00436231160.014
organophosphate catabolic processGO:00464342320.014
regulation of cell activationGO:00508652890.014
regulation of neuron differentiationGO:00456642810.014
response to light stimulusGO:00094161350.014
retina development in camera type eyeGO:00600411190.014
cellular lipid metabolic processGO:00442553230.014
skeletal system developmentGO:00015013560.014
negative regulation of apoptotic signaling pathwayGO:20012341040.013
Mouse
cellular calcium ion homeostasisGO:00068741190.013
muscle tissue developmentGO:00605373080.013
blood vessel morphogenesisGO:00485142850.013
respiratory tube developmentGO:00303231670.013
protein methylationGO:0006479810.013
carbohydrate derivative catabolic processGO:19011362310.013
apical constrictionGO:000338340.013
gtp catabolic processGO:00061841430.013
organic hydroxy compound metabolic processGO:19016152030.013
cellular carbohydrate metabolic processGO:00442621190.013
neural tube developmentGO:00219151600.013
hepaticobiliary system developmentGO:0061008670.013
ion transmembrane transportGO:00342203610.013
mitotic cell cycle processGO:19030471590.013
respiratory system developmentGO:00605411900.013
embryonic organ morphogenesisGO:00485622760.013
cell adhesionGO:00071553290.013
cellular metal ion homeostasisGO:00068751510.013
smoothened signaling pathwayGO:00072241050.013
purine nucleoside catabolic processGO:00061522050.013
organophosphate biosynthetic processGO:00904071220.013
regulation of purine nucleotide catabolic processGO:00331211220.013
regulation of system processGO:00440572000.013
muscle cell differentiationGO:00426922610.013
meiotic cell cycleGO:00513211220.013
regulation of vesicle mediated transportGO:00606271390.013
fat cell differentiationGO:00454441600.013
inorganic cation transmembrane transportGO:00986622070.012
regulation of muscle system processGO:0090257800.012
positive regulation of protein kinase activityGO:00458601440.012
genetic imprintingGO:0071514270.012
establishment of organelle localizationGO:00516561220.012
blood circulationGO:00080151950.012
cyclic nucleotide metabolic processGO:0009187590.012
regulation of protein kinase activityGO:00458592320.012
sensory perceptionGO:00076002450.012
regulation of metal ion transportGO:00109591060.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
negative regulation of phosphorus metabolic processGO:00105631840.012
regulation of establishment of protein localizationGO:00702011810.012
cation transmembrane transportGO:00986552660.012
regulation of endocytosisGO:0030100690.012
urogenital system developmentGO:00016552610.012
striated muscle tissue developmentGO:00147062930.012
negative regulation of immune system processGO:00026832090.012
leukocyte mediated immunityGO:00024431740.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
skeletal muscle organ developmentGO:00605381630.012
protein processingGO:00164851630.012
protein maturationGO:00516041760.012
purine containing compound catabolic processGO:00725232130.012
cellular response to organic cyclic compoundGO:0071407870.012
negative regulation of cell developmentGO:00107211690.012
protein glycosylationGO:0006486550.012
membrane organizationGO:00610242450.012
positive regulation of cellular catabolic processGO:00313311480.012
regulation of chromatin modificationGO:1903308570.012
negative regulation of phosphate metabolic processGO:00459361840.012
regulation of kinase activityGO:00435492490.012
negative regulation of protein modification processGO:00314001630.012
negative regulation of lymphocyte activationGO:0051250910.012
transforming growth factor beta receptor signaling pathwayGO:0007179710.012
synaptic vesicle transportGO:0048489570.012
lung developmentGO:00303241640.012
glycosylationGO:0070085620.012
ossificationGO:00015032160.012
positive regulation of protein phosphorylationGO:00019342420.012
regionalizationGO:00030023370.012
regulation of nucleoside metabolic processGO:00091181300.012
peptidyl lysine methylationGO:0018022290.012
cellular response to transforming growth factor beta stimulusGO:0071560880.012
b cell activationGO:00421131610.012
response to organonitrogen compoundGO:00102432460.011
histone h4 k20 methylationGO:003477080.011
histone h3 k9 trimethylationGO:003612460.011
mitotic cell cycleGO:00002781950.011
t cell activationGO:00421102890.011
establishment of vesicle localizationGO:0051650810.011
negative regulation of cell proliferationGO:00082852960.011
inorganic ion transmembrane transportGO:00986602340.011
neuron apoptotic processGO:00514021420.011
regulation of proteolysisGO:00301621640.011
morphogenesis of embryonic epitheliumGO:00163311590.011
glycoprotein metabolic processGO:00091001160.011
biomineral tissue developmentGO:0031214640.011
cell activation involved in immune responseGO:00022631260.011
regulation of transmembrane transportGO:00347621280.011
regulation of bindingGO:00510981110.011
nucleoside catabolic processGO:00091642060.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
mrna metabolic processGO:0016071840.011
regulation of neuron projection developmentGO:00109751690.011
oocyte constructionGO:000730820.011
leukocyte activation involved in immune responseGO:00023661260.011
compound eye developmentGO:004874910.011
response to peptideGO:19016521360.011
response to inorganic substanceGO:0010035960.011
cellular response to growth factor stimulusGO:00713631970.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
stem cell developmentGO:00488642190.011
mitotic cytokinesisGO:000028140.011
regulation of vasculature developmentGO:1901342880.011
regulation of voltage gated calcium channel activityGO:190138540.011
regulation of protein complex assemblyGO:0043254830.010
regulation of protein localizationGO:00328802310.010
protein alkylationGO:0008213810.010
heart contractionGO:0060047930.010
cellular response to lipidGO:00713961450.010
neural precursor cell proliferationGO:00613511210.010
blood coagulationGO:0007596760.010
regulation of neuron deathGO:19012141340.010
negative regulation of neuron deathGO:1901215980.010
asymmetric stem cell divisionGO:009872230.010
negative regulation of cell activationGO:00508661110.010
regulation of gtp catabolic processGO:00331241130.010
regulation of ion transmembrane transportGO:00347651190.010
response to transforming growth factor betaGO:0071559880.010
myeloid leukocyte differentiationGO:00025731190.010
myotube differentiationGO:00149021050.010

Klhl28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
organ system cancerDOID:005068600.016
nervous system diseaseDOID:86300.015
disease of anatomical entityDOID:700.015
musculoskeletal system diseaseDOID:1700.014
connective tissue diseaseDOID:6500.013
bone diseaseDOID:008000100.012