Mus musculus

240 known processes

Ticam1

toll-like receptor adaptor molecule 1

(Aliases: AW046014,TRIF,TICAM-1,AW547018)

Ticam1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to molecule of fungal originGO:000223840.985
i kappab kinase nf kappab signalingGO:0007249850.985
cellular response to peptidoglycanGO:007122440.978
positive regulation of interferon beta productionGO:003272880.927
detection of molecule of bacterial originGO:003249020.868
positive regulation of interferon alpha productionGO:003272740.864
positive regulation of interleukin 18 productionGO:003274120.860
toll like receptor signaling pathwayGO:0002224380.850
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.848
defense response to other organismGO:00985421970.838
positive regulation of chemokine productionGO:0032722220.835
cytokine biosynthetic processGO:0042089680.834
type i interferon biosynthetic processGO:004535190.832
activation of innate immune responseGO:0002218560.822
interleukin 8 productionGO:003263740.811
immune response regulating signaling pathwayGO:00027641250.794
pattern recognition receptor signaling pathwayGO:0002221470.793
regulation of innate immune responseGO:0045088910.771
myd88 dependent toll like receptor signaling pathwayGO:000275570.737
response to immune response of other organism involved in symbiotic interactionGO:005256430.706
regulation of cell activationGO:00508652890.690
regulation of interleukin 18 productionGO:003266130.684
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.683
positive regulation of type i interferon productionGO:0032481140.678
interleukin 23 productionGO:003262720.673
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.667
regulation of lymphocyte proliferationGO:00506701170.663
positive regulation of chemokine biosynthetic processGO:004508060.656
regulation of interferon beta biosynthetic processGO:004535740.653
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043420.602
interferon beta biosynthetic processGO:004535040.600
cytokine productionGO:00018163190.596
immune response activating cell surface receptor signaling pathwayGO:0002429720.594
regulation of defense responseGO:00313472330.562
type i interferon productionGO:0032606290.560
interleukin 18 productionGO:003262140.557
activation of immune responseGO:00022531380.556
response to bacterial lipoproteinGO:003249340.546
negative regulation of t cell activationGO:0050868650.525
regulation of interleukin 23 productionGO:003266720.523
regulation of leukocyte proliferationGO:00706631210.511
interleukin 17 productionGO:0032620110.510
negative regulation of epidermal growth factor activated receptor activityGO:000717530.478
cytokine mediated signaling pathwayGO:00192211150.474
Mouse
regulation of lymphocyte activationGO:00512492400.457
positive regulation of nitric oxide synthase biosynthetic processGO:005177060.443
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.438
innate immune response activating cell surface receptor signaling pathwayGO:000222040.437
positive regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042620.418
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.413
positive regulation of interleukin 8 productionGO:003275720.399
regulation of cytokine biosynthetic processGO:0042035590.397
cellular response to molecule of bacterial originGO:0071219830.390
positive regulation of interleukin 6 productionGO:0032755370.388
lymphocyte proliferationGO:00466511640.380
interferon beta productionGO:0032608160.379
positive regulation of b cell activationGO:0050871490.376
cellular response to lipoteichoic acidGO:007122360.375
modulation by symbiont of defense related host nitric oxide productionGO:005216310.357
negative regulation of t cell proliferationGO:0042130380.354
positive regulation of mhc class ii biosynthetic processGO:004534840.348
regulation of tumor necrosis factor productionGO:0032680490.346
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.339
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.332
carbohydrate metabolic processGO:00059752300.327
negative regulation of leukocyte proliferationGO:0070664460.326
induction by organism of defense response of other organism involved in symbiotic interactionGO:005225110.326
positive regulation of lymphocyte proliferationGO:0050671700.322
positive regulation by symbiont of host defense responseGO:005250910.316
response to hostGO:007513630.310
positive regulation of cytokine biosynthetic processGO:0042108400.308
positive regulation of lymphocyte activationGO:00512511400.306
regulation of type i interferon productionGO:0032479220.306
negative regulation of lymphocyte proliferationGO:0050672450.300
response to host immune responseGO:005257230.291
immune response activating signal transductionGO:00027571160.288
regulation of interleukin 17 productionGO:003266080.284
positive regulation of interferon beta biosynthetic processGO:004535930.281
positive regulation of cell activationGO:00508671580.274
response to defense related host nitric oxide productionGO:005256520.273
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.271
regulation of response to biotic stimulusGO:0002831380.270
growth involved in symbiotic interactionGO:0044110230.267
positive regulation of antimicrobial peptide productionGO:000222510.266
innate immune response activating signal transductionGO:0002758500.266
t cell activationGO:00421102890.264
regulation of interleukin 8 productionGO:003267730.263
regulation of sequence specific dna binding transcription factor activityGO:00510901060.253
positive regulation of macrophage cytokine productionGO:006090770.253
regulation of cellular ketone metabolic processGO:0010565660.248
regulation of inflammatory responseGO:00507271470.248
response to host defensesGO:005220030.243
positive regulation by symbiont of host immune responseGO:005255610.241
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005230210.240
lipopolysaccharide mediated signaling pathwayGO:0031663250.235
negative regulation of hormone biosynthetic processGO:003235340.233
production of molecular mediator of immune responseGO:00024401030.232
response to lipoteichoic acidGO:007039160.230
cellular response to bacterial lipopeptideGO:007122130.230
multicellular organismal homeostasisGO:00488711640.230
positive regulation of defense responseGO:00313491240.229
modulation by symbiont of host immune responseGO:005255310.229
antimicrobial peptide productionGO:000277520.225
stress activated protein kinase signaling cascadeGO:0031098810.225
regulation of cellular amine metabolic processGO:0033238200.223
negative regulation of lymphocyte activationGO:0051250910.223
cellular response to cytokine stimulusGO:00713451890.216
Mouse
tumor necrosis factor superfamily cytokine productionGO:0071706510.214
regulation of cellular amino acid metabolic processGO:000652150.214
nitric oxide synthase biosynthetic processGO:005176770.211
antibacterial peptide biosynthetic processGO:000278020.209
response to lipopolysaccharideGO:00324961280.208
response to defenses of other organism involved in symbiotic interactionGO:005217330.208
induction by symbiont of host immune responseGO:005255910.205
regulation of establishment of protein localizationGO:00702011810.202
positive regulation of cytokine productionGO:00018191740.202
regulation of secretionGO:00510462740.199
positive regulation of antimicrobial humoral responseGO:000276020.199
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.199
modulation of growth of symbiont involved in interaction with hostGO:0044144190.197
cellular amino acid metabolic processGO:00065201030.195
regulation of antimicrobial peptide productionGO:000278410.194
chemokine biosynthetic processGO:004203380.192
cellular amine metabolic processGO:0044106440.192
cellular ketone metabolic processGO:0042180840.190
positive regulation of protein transportGO:0051222930.185
negative regulation of cytokine productionGO:0001818840.183
positive regulation by organism of defense response of other organism involved in symbiotic interactionGO:005251010.182
type i interferon signaling pathwayGO:0060337100.181
regionalizationGO:00030023370.180
immune response regulating cell surface receptor signaling pathwayGO:0002768800.175
regulation of macrophage cytokine productionGO:001093580.171
regulation of chemokine productionGO:0032642300.169
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.168
response to molecule of bacterial originGO:00022371430.168
growth of symbiont in hostGO:0044117230.166
modification by symbiont of host morphology or physiologyGO:004400340.163
t cell proliferationGO:00420981200.160
negative regulation of cell proliferationGO:00082852960.160
response to bacterial lipopeptideGO:007033930.159
negative regulation of interleukin 6 productionGO:0032715170.158
stress activated mapk cascadeGO:0051403800.158
negative regulation of phosphate metabolic processGO:00459361840.158
regulation of interleukin 10 productionGO:0032653210.157
positive regulation of leukocyte proliferationGO:0070665730.156
cellular response to biotic stimulusGO:0071216920.155
chemokine metabolic processGO:0050755100.154
cellular response to bacterial lipoproteinGO:007122030.150
regulation of interferon beta productionGO:0032648130.145
positive regulation of interleukin 6 biosynthetic processGO:004541060.145
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.144
protein targetingGO:00066051430.141
regulation of antimicrobial humoral responseGO:000275930.141
regulation of natural killer cell activationGO:0032814220.140
regulation of alpha beta t cell activationGO:0046634530.138
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.137
regulation of growth of symbiont in hostGO:0044126190.136
regulation of stress activated mapk cascadeGO:0032872690.135
regulation of defense response to bacteriumGO:190042430.135
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005226310.134
regulation of b cell proliferationGO:0030888390.134
intracellular receptor signaling pathwayGO:0030522740.130
regulation of b cell activationGO:0050864810.129
leukocyte proliferationGO:00706611720.128
regulation of jnk cascadeGO:0046328620.128
alpha beta t cell proliferationGO:0046633210.127
regulation of secretion by cellGO:19035302490.127
immune effector processGO:00022523210.126
cellular response to lipidGO:00713961450.126
negative regulation of cell activationGO:00508661110.125
positive regulation of innate immune responseGO:0045089800.125
response to organic cyclic compoundGO:00140701980.125
negative regulation of growth of symbiont in hostGO:0044130190.124
regulation of response to woundingGO:19030341890.124
defense response to bacteriumGO:00427421190.123
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005234510.121
antibiotic transportGO:004289110.120
response to peptidoglycanGO:003249490.118
inflammatory responseGO:00069542440.117
interspecies interaction between organismsGO:0044419830.117
regulation of protein transportGO:00512231630.117
b cell proliferationGO:0042100530.115
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.113
regulation of production of molecular mediator of immune responseGO:0002700650.113
regulation of interleukin 1 productionGO:0032652260.111
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.110
macromolecule catabolic processGO:00090572810.110
regulation of carbohydrate metabolic processGO:0006109750.108
positive regulation of t cell anergyGO:000266940.108
positive regulation of production of molecular mediator of immune responseGO:0002702450.108
eye photoreceptor cell differentiationGO:0001754410.108
nitric oxide production involved in inflammatory responseGO:000253720.107
negative regulation of interferon gamma productionGO:0032689180.106
t cell anergyGO:000287040.106
regulation of t cell proliferationGO:0042129920.105
positive regulation of jnk cascadeGO:0046330460.104
response to dsrnaGO:0043331300.104
negative regulation of hormone metabolic processGO:003235140.104
intestinal epithelial structure maintenanceGO:006072940.103
reactive oxygen species metabolic processGO:0072593840.103
positive regulation of secretionGO:00510471300.101
positive regulation of lymphocyte anergyGO:000291340.101
microglial cell activationGO:000177430.100
growth of symbiont involved in interaction with hostGO:0044116230.099
regulation of lymphocyte anergyGO:000291140.098
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.097
negative regulation of phosphorus metabolic processGO:00105631840.097
regulation of defense response to fungusGO:190015010.097
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.096
regulation of antigen receptor mediated signaling pathwayGO:0050854290.096
peptidyl tyrosine phosphorylationGO:00181081430.096
macrophage cytokine productionGO:001093490.095
modulation by organism of immune response of other organism involved in symbiotic interactionGO:005255210.095
regulation of t cell anergyGO:000266740.094
tumor necrosis factor mediated signaling pathwayGO:0033209130.091
regulation of cellular response to stressGO:00801351590.091
glycoprotein biosynthetic processGO:0009101890.090
tissue homeostasisGO:00018941150.090
symbiosis encompassing mutualism through parasitismGO:0044403830.089
negative regulation of immune system processGO:00026832090.088
positive regulation of interleukin 10 productionGO:0032733120.087
b cell activationGO:00421131610.086
regulation of interferon alpha productionGO:003264750.085
glycoprotein metabolic processGO:00091001160.083
modulation by organism of defense response of other organism involved in symbiotic interactionGO:005225510.083
regulation of cytokine productionGO:00018172660.082
mapk cascadeGO:00001652810.081
t cell homeostasisGO:0043029350.079
regulation of protein kinase activityGO:00458592320.079
programmed necrotic cell deathGO:0097300280.078
interleukin 10 productionGO:0032613230.078
regulation of alpha beta t cell proliferationGO:0046640180.077
positive regulation of protein modification processGO:00314012990.077
innate immune responseGO:00450871570.077
jnk cascadeGO:0007254720.075
protein catabolic processGO:00301632210.074
antibacterial peptide productionGO:000277820.073
antigen receptor mediated signaling pathwayGO:0050851640.072
negative regulation of protein modification processGO:00314001630.071
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.071
defense response to virusGO:0051607680.069
regulation of reactive oxygen species biosynthetic processGO:190342620.068
detection of lipopolysaccharideGO:003249710.068
regulation of protein import into nucleus translocationGO:003315820.068
anatomical structure homeostasisGO:00602491450.066
lymphocyte mediated immunityGO:00024491390.065
regulation of transferase activityGO:00513382630.064
regulation of antibacterial peptide biosynthetic processGO:000280810.063
chloramphenicol transportGO:004289210.063
regulation of hormone levelsGO:00108172110.062
regulation of antimicrobial peptide biosynthetic processGO:000280510.062
negative regulation of erk1 and erk2 cascadeGO:0070373210.061
b cell activation involved in immune responseGO:0002312500.061
3 utr mediated mrna stabilizationGO:007093520.060
intrinsic apoptotic signaling pathwayGO:00971931320.060
adaptive immune responseGO:00022501550.060
positive regulation of transcription factor import into nucleusGO:004299380.060
cellular response to organonitrogen compoundGO:00714171450.060
positive regulation of secretion by cellGO:19035321140.060
regulation of body fluid levelsGO:00508781620.060
defense response to gram positive bacteriumGO:0050830500.060
negative regulation of multi organism processGO:0043901680.059
regulation of intracellular protein transportGO:0033157820.058
positive regulation of protein secretionGO:0050714520.057
peptidyl amino acid modificationGO:00181933360.056
induction by symbiont of defense related host nitric oxide productionGO:005206310.055
cellular response to lipopolysaccharideGO:0071222770.055
lymphocyte anergyGO:000224940.055
defense response to gram negative bacteriumGO:0050829280.054
regulation of chemokine biosynthetic processGO:004507380.053
interferon alpha productionGO:003260770.053
positive regulation of mapk cascadeGO:00434101700.053
cellular carbohydrate metabolic processGO:00442621190.053
response to organonitrogen compoundGO:00102432460.053
sensory organ morphogenesisGO:00905962420.052
response to interleukin 1GO:0070555110.052
b cell proliferation involved in immune responseGO:000232250.052
cytokine metabolic processGO:0042107710.052
regulation of cytokine secretionGO:0050707610.051
organic acid transportGO:00158491010.051
positive regulation of multi organism processGO:0043902260.050
interleukin 1 mediated signaling pathwayGO:007049840.049
macrophage activationGO:0042116270.049
regulation of inflammatory response to antigenic stimulusGO:0002861210.049
cytoplasmic transportGO:00164822340.049
regulation of protein localizationGO:00328802310.049
necroptotic processGO:0070266210.048
cellular response to external stimulusGO:0071496880.048
positive regulation of response to biotic stimulusGO:0002833150.048
amine metabolic processGO:0009308450.048
regulation of cell migrationGO:00303342190.047
interleukin 6 biosynthetic processGO:0042226120.047
interleukin 6 productionGO:0032635580.047
neuronal action potentialGO:0019228540.047
protein maturationGO:00516041760.046
membrane organizationGO:00610242450.046
protein ubiquitinationGO:00165671710.045
sensory perception of painGO:0019233470.045
negative regulation of interleukin 23 productionGO:003270710.045
regulation of t cell activationGO:00508631700.044
positive regulation of stress activated mapk cascadeGO:0032874480.044
nitrogen compound transportGO:00717052710.044
protein secretionGO:00093061110.044
toxin transportGO:1901998380.044
negative regulation of cellular amine metabolic processGO:003323910.043
regulation of interleukin 6 productionGO:0032675550.043
intracellular protein transportGO:00068862040.043
positive regulation of transferase activityGO:00513471670.043
monocarboxylic acid metabolic processGO:00327871910.042
positive regulation of programmed cell deathGO:00430682180.042
germ cell developmentGO:00072811850.042
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.042
positive regulation of intracellular transportGO:0032388700.042
regulation of interleukin 12 productionGO:0032655300.041
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.041
fatty acid metabolic processGO:00066311210.041
positive regulation of tumor necrosis factor productionGO:0032760300.041
positive regulation of apoptotic processGO:00430652170.041
glial cell apoptotic processGO:003434930.041
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.040
negative regulation of intracellular signal transductionGO:19025321670.040
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.040
toll like receptor 4 signaling pathwayGO:003414290.040
positive regulation of cytokine secretionGO:0050715410.040
positive regulation of nf kappab transcription factor activityGO:0051092300.040
positive regulation of interleukin 17 productionGO:003274030.040
nucleoside metabolic processGO:00091162460.039
carbohydrate derivative biosynthetic processGO:19011371830.039
positive regulation of interferon gamma productionGO:0032729390.039
Mouse
regulation of cell motilityGO:20001452360.039
apoptotic signaling pathwayGO:00971903060.039
regulation of platelet activationGO:0010543170.038
negative regulation of kinase activityGO:0033673810.038
positive regulation of b cell proliferationGO:0030890240.038
peptide transportGO:00158331330.038
photoreceptor cell differentiationGO:0046530520.037
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.037
positive regulation of myeloid leukocyte cytokine production involved in immune responseGO:006108190.037
response to interleukin 12GO:007067120.037
Mouse
protein polyubiquitinationGO:0000209330.037
cellularizationGO:000734910.037
regulation of mapk cascadeGO:00434082480.037
positive regulation of immune effector processGO:00026991070.036
regulation of defense response to virus by hostGO:005069180.036
defense response to fungusGO:0050832120.036
cellular lipid metabolic processGO:00442553230.036
digestionGO:0007586400.036
positive regulation of protein localization to nucleusGO:1900182300.036
positive regulation of interleukin 1 productionGO:0032732170.035
necrotic cell deathGO:0070265300.035
regulation of acute inflammatory responseGO:0002673270.035
interleukin 1 productionGO:0032612310.035
somatic diversification of immune receptorsGO:0002200530.034
production of molecular mediator involved in inflammatory responseGO:0002532210.034
engulfment of apoptotic cellGO:004365230.034
negative regulation of cellular amino acid metabolic processGO:004576300.034
cd4 positive alpha beta t cell differentiationGO:0043367410.034
rig i signaling pathwayGO:003952940.033
regulation of defense response to virusGO:0050688180.033
regulation of hydrolase activityGO:00513362460.033
positive regulation by organism of immune response of other organism involved in symbiotic interactionGO:005255510.033
regulation of protein serine threonine kinase activityGO:00719001570.033
positive regulation of response to cytokine stimulusGO:0060760110.032
Mouse
compound eye developmentGO:004874910.032
monocarboxylic acid transportGO:0015718440.032
carboxylic acid transportGO:00469421000.032
immunoglobulin mediated immune responseGO:0016064690.032
regulation of rna stabilityGO:0043487260.032
positive regulation of endopeptidase activityGO:0010950430.032
angiogenesisGO:00015252010.032
response to type i interferonGO:0034340120.032
b cell mediated immunityGO:0019724710.031
regulation of transcription factor import into nucleusGO:0042990240.031
regulation of intracellular transportGO:00323861590.031
immunoglobulin secretionGO:0048305170.031
positive regulation of type i interferon mediated signaling pathwayGO:006034040.031
regulation of cytoplasmic transportGO:19036491120.031
epithelial structure maintenanceGO:001066990.031
positive regulation of t cell proliferationGO:0042102520.031
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.030
antimicrobial peptide biosynthetic processGO:000277720.030
negative regulation of protein tyrosine kinase activityGO:006109930.030
regulation of apoptotic signaling pathwayGO:20012331970.030
lymphocyte apoptotic processGO:0070227540.030
dna recombinationGO:0006310920.030
positive regulation of protein import into nucleusGO:0042307260.030
regulation of leukocyte differentiationGO:19021051590.029
regulation of endopeptidase activityGO:0052548890.029
negative regulation of inflammatory responseGO:0050728610.029
nucleocytoplasmic transportGO:00069131390.029
cell adhesionGO:00071553290.029
regulation of protein targetingGO:1903533610.029
protein localization to organelleGO:00333651850.029
positive regulation of inflammatory responseGO:0050729470.029
alpha amino acid metabolic processGO:1901605590.029
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.029
transcription factor import into nucleusGO:0042991260.028
leukocyte mediated immunityGO:00024431740.028
amide transportGO:00428861380.028
drug transportGO:001589370.028
positive regulation of cytokine production involved in immune responseGO:0002720190.027
cellular response to abiotic stimulusGO:0071214560.027
regulation of kinase activityGO:00435492490.027
chemokine productionGO:0032602340.027
interaction with hostGO:0051701220.027
regulation of protein secretionGO:0050708820.027
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.027
male gamete generationGO:00482322850.027
positive regulation of leukocyte mediated immunityGO:0002705700.027
nucleobase containing small molecule metabolic processGO:00550863520.027
coagulationGO:0050817780.027
lipid localizationGO:00108761260.026
negative regulation of growthGO:0045926990.026
type 2 immune responseGO:0042092230.026
reactive nitrogen species metabolic processGO:200105700.026
positive regulation of platelet activationGO:001057250.026
isotype switchingGO:0045190360.026
cellular response to oxidative stressGO:0034599760.026
cell surface pattern recognition receptor signaling pathwayGO:000275220.026
transmembrane transportGO:00550854120.026
ion transmembrane transportGO:00342203610.025
sensory perceptionGO:00076002450.025
posttranscriptional regulation of gene expressionGO:00106081550.025
response to exogenous dsrnaGO:0043330220.024
positive regulation of t cell activationGO:00508701010.024
regulation of mast cell proliferationGO:007066640.024
skin developmentGO:00435882200.024
organic cyclic compound catabolic processGO:19013612950.024
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.024
endocytosisGO:00068971680.024
establishment of protein localization to organelleGO:00725941180.024
myd88 independent toll like receptor signaling pathwayGO:000275630.024
response to peptide hormoneGO:00434341270.024
regulation of nucleocytoplasmic transportGO:0046822730.024
alpha beta t cell activationGO:0046631910.024
regulation of response to cytokine stimulusGO:0060759230.023
Mouse
glycosylationGO:0070085620.023
regulation of cytokine production involved in immune responseGO:0002718260.023
negative regulation of interleukin 17 productionGO:003270050.023
positive regulation of autophagyGO:001050890.023
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.023
negative regulation of protein metabolic processGO:00512482820.023
endomembrane system organizationGO:00102561470.023
macromolecule glycosylationGO:0043413550.023
lymphocyte differentiationGO:00300982420.023
heterocycle catabolic processGO:00467002800.023
somatic recombination of immunoglobulin gene segmentsGO:0016447420.023
hormone biosynthetic processGO:0042446160.023
regulation of membrane potentialGO:00423911920.023
mitotic cytokinesisGO:000028140.023
regulation of receptor activityGO:0010469410.023
icosanoid metabolic processGO:0006690330.022
tumor necrosis factor productionGO:0032640500.022
regulation of cell cycleGO:00517262810.022
positive regulation of protein catabolic processGO:0045732600.022
positive regulation of intracellular protein transportGO:0090316420.022
regulation of nitric oxide synthase biosynthetic processGO:005176970.022
regulation of ion transportGO:00432692150.022
positive regulation of lymphocyte mediated immunityGO:0002708620.022
platelet activationGO:0030168400.022
regulation of coagulationGO:0050818310.022
t cell selectionGO:0045058340.022
response to acid chemicalGO:00011011110.022
nucleoside triphosphate metabolic processGO:00091412300.021
sequestering of calcium ionGO:0051208180.021
i kappab phosphorylationGO:000725260.021
wnt signaling pathwayGO:00160551880.021
maintenance of locationGO:0051235890.021
positive regulation of protein kinase activityGO:00458601440.021
protein glycosylationGO:0006486550.021
translationGO:0006412930.021
regulation of toll like receptor 4 signaling pathwayGO:003414340.021
regulation of multi organism processGO:00439001110.021
cellular ion homeostasisGO:00068731650.021
dna metabolic processGO:00062593030.021
cellular amide metabolic processGO:0043603580.021
mast cell proliferationGO:007066240.021
aromatic compound catabolic processGO:00194392860.021
cytokine secretionGO:0050663720.021
protein modification by small protein conjugation or removalGO:00706472070.021

Ticam1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.201
cancerDOID:16200.201
organ system cancerDOID:005068600.139
immune system cancerDOID:006008300.076
nervous system diseaseDOID:86300.072
disease of anatomical entityDOID:700.072
hematologic cancerDOID:253100.067
sensory system diseaseDOID:005015500.039
eye and adnexa diseaseDOID:149200.039
retinal diseaseDOID:567900.036
retinal degenerationDOID:846600.036
eye diseaseDOID:561400.036
macular degenerationDOID:444800.029
gastrointestinal system cancerDOID:311900.022
intestinal cancerDOID:1015500.022
colorectal cancerDOID:925600.022
large intestine cancerDOID:567200.022
colon cancerDOID:21900.022
disease of metabolismDOID:001466700.021