Mus musculus

112 known processes

Spred2

sprouty-related, EVH1 domain containing 2

(Aliases: C79158)

Spred2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amino acid metabolic processGO:000652150.098
nucleoside phosphate metabolic processGO:00067533380.082
cell adhesionGO:00071553290.071
cellular ketone metabolic processGO:0042180840.071
cellular amino acid metabolic processGO:00065201030.064
negative regulation of cellular protein metabolic processGO:00322692470.063
regionalizationGO:00030023370.063
purine nucleotide metabolic processGO:00061633020.060
negative regulation of cellular amine metabolic processGO:003323910.059
regulation of cellular ketone metabolic processGO:0010565660.058
proteolysis involved in cellular protein catabolic processGO:00516031470.056
regulation of cellular amine metabolic processGO:0033238200.055
small gtpase mediated signal transductionGO:0007264970.055
regulation of hydrolase activityGO:00513362460.055
cellular amine metabolic processGO:0044106440.053
male gamete generationGO:00482322850.053
mapk cascadeGO:00001652810.052
oocyte constructionGO:000730820.052
camera type eye developmentGO:00430102660.052
regulation of cellular catabolic processGO:00313292420.051
ribonucleoside metabolic processGO:00091192450.051
amine metabolic processGO:0009308450.049
negative regulation of protein modification processGO:00314001630.049
developmental maturationGO:00217001930.048
spermatogenesisGO:00072832840.048
nucleoside metabolic processGO:00091162460.047
ribonucleotide metabolic processGO:00092592910.047
nucleobase containing small molecule metabolic processGO:00550863520.047
ras protein signal transductionGO:0007265770.047
gland developmentGO:00487323300.046
purine containing compound metabolic processGO:00725213110.045
stem cell differentiationGO:00488632680.045
negative regulation of cell proliferationGO:00082852960.044
cellular macromolecule catabolic processGO:00442652060.043
regulation of purine nucleotide metabolic processGO:19005421690.043
macromolecule catabolic processGO:00090572810.042
nucleotide metabolic processGO:00091173320.042
dephosphorylationGO:00163111290.042
cell type specific apoptotic processGO:00972852680.041
rho protein signal transductionGO:0007266320.040
purine ribonucleoside triphosphate catabolic processGO:00092071990.040
organophosphate catabolic processGO:00464342320.040
epithelial tube morphogenesisGO:00605623030.039
Mouse
respiratory tube developmentGO:00303231670.038
negative regulation of protein metabolic processGO:00512482820.038
regulation of kinase activityGO:00435492490.038
negative regulation of cellular amino acid metabolic processGO:004576300.037
axonogenesisGO:00074092740.037
Mouse
protein catabolic processGO:00301632210.036
nucleoside triphosphate catabolic processGO:00091432050.036
negative regulation of phosphorus metabolic processGO:00105631840.036
purine containing compound catabolic processGO:00725232130.035
cellular protein catabolic processGO:00442571550.035
apoptotic signaling pathwayGO:00971903060.035
purine nucleoside metabolic processGO:00422782410.035
oocyte axis specificationGO:000730920.035
cellular nitrogen compound catabolic processGO:00442702800.035
nucleoside phosphate catabolic processGO:19012922220.033
regulation of cell cycleGO:00517262810.033
heterocycle catabolic processGO:00467002800.033
protein modification by small protein conjugation or removalGO:00706472070.033
negative regulation of nervous system developmentGO:00519611560.032
purine ribonucleoside triphosphate metabolic processGO:00092052200.032
ribose phosphate metabolic processGO:00196932910.032
chemotaxisGO:00069352470.032
Mouse
positive regulation of cellular catabolic processGO:00313311480.032
neural tube developmentGO:00219151600.032
Mouse
negative regulation of phosphate metabolic processGO:00459361840.031
actin cytoskeleton organizationGO:00300362200.031
Mouse
negative regulation of cellular component organizationGO:00511291940.031
regulation of organelle organizationGO:00330432890.031
Mouse
negative regulation of protein phosphorylationGO:00019331260.030
gtp catabolic processGO:00061841430.030
cytoplasmic transportGO:00164822340.030
carbohydrate derivative biosynthetic processGO:19011371830.030
cell fate commitmentGO:00451652100.030
ion transmembrane transportGO:00342203610.030
regulation of mapk cascadeGO:00434082480.030
single organism cell adhesionGO:00986021560.030
regulation of cellular response to stressGO:00801351590.030
purine nucleoside triphosphate catabolic processGO:00091462030.030
carbohydrate derivative catabolic processGO:19011362310.030
skeletal system developmentGO:00015013560.030
modification dependent protein catabolic processGO:00199411330.029
ribonucleoside catabolic processGO:00424542060.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
ribonucleotide catabolic processGO:00092612080.029
purine ribonucleoside metabolic processGO:00461282410.029
protein ubiquitinationGO:00165671710.028
purine ribonucleotide metabolic processGO:00091502900.028
glycosyl compound metabolic processGO:19016572460.028
regulation of apoptotic signaling pathwayGO:20012331970.028
organic cyclic compound catabolic processGO:19013612950.028
regulation of system processGO:00440572000.028
modification dependent macromolecule catabolic processGO:00436321330.028
negative regulation of molecular functionGO:00440922580.027
purine nucleotide catabolic processGO:00061952110.027
fat cell differentiationGO:00454441600.027
muscle system processGO:00030121410.027
regulation of ras protein signal transductionGO:00465781140.027
positive regulation of purine nucleotide metabolic processGO:19005441140.027
ossificationGO:00015032160.027
guanosine containing compound catabolic processGO:19010691440.027
transmembrane transportGO:00550854120.026
maternal determination of anterior posterior axis embryoGO:000835820.026
respiratory system developmentGO:00605411900.026
protein modification by small protein conjugationGO:00324461870.026
peptidyl amino acid modificationGO:00181933360.025
protein maturationGO:00516041760.025
response to growth factorGO:00708481980.025
wnt signaling pathwayGO:00160551880.025
nucleoside triphosphate metabolic processGO:00091412300.025
organonitrogen compound catabolic processGO:19015652640.025
muscle tissue developmentGO:00605373080.025
striated muscle tissue developmentGO:00147062930.025
chromatin organizationGO:00063252060.025
lymphocyte differentiationGO:00300982420.025
guanosine containing compound metabolic processGO:19010681440.024
regulation of cell migrationGO:00303342190.024
single organismal cell cell adhesionGO:00163371310.024
cell maturationGO:00484691270.024
nucleotide catabolic processGO:00091662170.024
regulation of nucleotide metabolic processGO:00061401690.024
oocyte anterior posterior axis specificationGO:000731420.024
regulation of membrane potentialGO:00423911920.024
cell growthGO:00160491300.024
glycosyl compound catabolic processGO:19016582060.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
germ cell developmentGO:00072811850.024
negative regulation of cell developmentGO:00107211690.024
microtubule based processGO:00070172360.023
myeloid cell differentiationGO:00300992330.023
cellular response to growth factor stimulusGO:00713631970.022
extrinsic apoptotic signaling pathwayGO:00971911260.022
circulatory system processGO:00030131970.022
ubiquitin dependent protein catabolic processGO:00065111290.022
developmental growth involved in morphogenesisGO:00605601380.022
telencephalon developmentGO:00215371860.022
dna metabolic processGO:00062593030.022
regulation of cellular component biogenesisGO:00440871810.022
Mouse
response to molecule of bacterial originGO:00022371430.022
lung developmentGO:00303241640.022
regulation of cell projection organizationGO:00313442060.022
blood vessel morphogenesisGO:00485142850.022
regulation of purine nucleotide catabolic processGO:00331211220.022
cation transmembrane transportGO:00986552660.022
organonitrogen compound biosynthetic processGO:19015661920.022
cellular response to dna damage stimulusGO:00069742070.021
pole plasm assemblyGO:000731520.021
purine ribonucleoside catabolic processGO:00461302050.021
aromatic compound catabolic processGO:00194392860.021
forebrain developmentGO:00309003020.021
regulation of gtp catabolic processGO:00331241130.021
homeostasis of number of cellsGO:00488722100.021
negative regulation of apoptotic signaling pathwayGO:20012341040.021
regulation of anatomical structure sizeGO:00900661780.021
Mouse
establishment or maintenance of cytoskeleton polarityGO:003095220.021
ribonucleoside triphosphate catabolic processGO:00092031990.021
regulation of nucleoside metabolic processGO:00091181300.021
mitotic cell cycle processGO:19030471590.021
chromatin modificationGO:00165681870.021
gtp metabolic processGO:00460391440.021
cation transportGO:00068123990.021
epithelial tube formationGO:00721751300.021
Mouse
sensory perceptionGO:00076002450.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.021
positive regulation of cellular amine metabolic processGO:003324050.021
microtubule cytoskeleton organizationGO:00002261570.020
positive regulation of nucleotide metabolic processGO:00459811140.020
multicellular organismal signalingGO:0035637910.020
placenta developmentGO:00018901400.020
regulation of cell morphogenesis involved in differentiationGO:00107691510.020
response to organonitrogen compoundGO:00102432460.020
leukocyte differentiationGO:00025213420.020
gliogenesisGO:00420631410.020
ameboidal type cell migrationGO:00016671280.020
regulation of ion transportGO:00432692150.020
nucleoside catabolic processGO:00091642060.020
sensory organ morphogenesisGO:00905962420.020
morphogenesis of a branching structureGO:00017632030.020
stem cell developmentGO:00488642190.019
nitrogen compound transportGO:00717052710.019
negative regulation of phosphorylationGO:00423261660.019
regulation of nucleotide catabolic processGO:00308111220.019
regulation of cell activationGO:00508652890.019
negative regulation of intracellular signal transductionGO:19025321670.019
organelle fissionGO:00482851700.019
endocytosisGO:00068971680.019
cell divisionGO:00513011200.019
g protein coupled receptor signaling pathwayGO:00071862430.019
blood circulationGO:00080151950.019
mitochondrion organizationGO:00070051340.019
bone developmentGO:00603481200.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
heart morphogenesisGO:00030071780.019
positive regulation of hydrolase activityGO:00513451480.019
regulation of lymphocyte activationGO:00512492400.019
regulation of neuron projection developmentGO:00109751690.019
regulation of ras gtpase activityGO:0032318880.019
covalent chromatin modificationGO:00165691630.019
response to lipopolysaccharideGO:00324961280.018
action potentialGO:0001508780.018
intracellular protein transportGO:00068862040.018
regulation of cell motilityGO:20001452360.018
positive regulation of cell developmentGO:00107202370.018
endomembrane system organizationGO:00102561470.018
t cell activationGO:00421102890.018
nuclear divisionGO:00002801580.018
cellular protein complex assemblyGO:00436231160.018
Mouse
hematopoietic progenitor cell differentiationGO:00022441430.018
morphogenesis of embryonic epitheliumGO:00163311590.018
Mouse
regulation of transferase activityGO:00513382630.018
digestive system developmentGO:00551232000.018
negative regulation of neuron differentiationGO:00456651010.018
cellular response to cytokine stimulusGO:00713451890.017
epithelial cell proliferationGO:00506731740.017
adaptive immune responseGO:00022501550.017
angiogenesisGO:00015252010.017
primary neural tube formationGO:0014020950.017
Mouse
purine nucleoside catabolic processGO:00061522050.017
skin developmentGO:00435882200.017
positive regulation of nucleoside metabolic processGO:0045979910.017
muscle cell differentiationGO:00426922610.017
regulation of inflammatory responseGO:00507271470.017
positive regulation of mapk cascadeGO:00434101700.017
digestive tract developmentGO:00485651900.017
regulation of cellular component sizeGO:00325351210.017
Mouse
regulation of erk1 and erk2 cascadeGO:0070372710.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
oxidation reduction processGO:00551143420.016
regulation of protein kinase activityGO:00458592320.016
embryonic epithelial tube formationGO:00018381300.016
Mouse
purine ribonucleotide catabolic processGO:00091542080.016
t cell differentiationGO:00302171740.016
cytokine mediated signaling pathwayGO:00192211150.016
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.016
intracellular mrna localizationGO:000829840.016
actin filament organizationGO:00070151130.016
Mouse
cellular lipid metabolic processGO:00442553230.016
inflammatory responseGO:00069542440.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of epithelial cell proliferationGO:00506781410.016
rhythmic processGO:00485111740.015
negative regulation of immune system processGO:00026832090.015
locomotory behaviorGO:00076261950.015
anion transportGO:00068201770.015
mesodermal cell migrationGO:000807840.015
retina development in camera type eyeGO:00600411190.015
female gamete generationGO:0007292740.015
photoreceptor cell morphogenesisGO:000859430.015
regulation of map kinase activityGO:00434051200.015
myeloid cell homeostasisGO:00022621140.015
histone modificationGO:00165701590.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
negative regulation of kinase activityGO:0033673810.015
positive regulation of protein modification processGO:00314012990.015
actin filament polymerizationGO:0030041440.015
Mouse
transmission of nerve impulseGO:0019226760.015
nucleotide biosynthetic processGO:0009165780.015
maintenance of locationGO:0051235890.015
cellular response to lipidGO:00713961450.015
organ growthGO:00352651170.015
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.015
carbohydrate metabolic processGO:00059752300.015
developmental cell growthGO:0048588840.015
muscle contractionGO:00069361010.015
regulation of organ morphogenesisGO:20000271440.015
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.015
multicellular organismal homeostasisGO:00488711640.015
regulation of leukocyte differentiationGO:19021051590.015
response to radiationGO:00093141650.014
tissue homeostasisGO:00018941150.014
leukocyte proliferationGO:00706611720.014
synaptic transmissionGO:00072683290.014
fertilizationGO:00095661270.014
cellular response to hormone stimulusGO:00328701500.014
positive regulation of nervous system developmentGO:00519622210.014
positive regulation of transferase activityGO:00513471670.014
neural tube formationGO:00018411080.014
Mouse
glycoprotein metabolic processGO:00091001160.014
sequestering of calcium ionGO:0051208180.014
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.014
positive regulation of organelle organizationGO:00106381280.014
Mouse
gonad developmentGO:00084061410.014
immune effector processGO:00022523210.014
multicellular organism growthGO:00352641610.014
b cell differentiationGO:0030183780.014
positive regulation of gtp catabolic processGO:0033126850.014
adult behaviorGO:00305341350.014
lymphocyte mediated immunityGO:00024491390.014
positive regulation of apoptotic signaling pathwayGO:2001235950.014
synapse organizationGO:00508081250.014
cardiac chamber developmentGO:00032051080.014
epithelial cell developmentGO:00020641590.014
positive regulation of cell migrationGO:00303351090.014
regulation of t cell activationGO:00508631700.013
hindbrain developmentGO:00309021280.013
skeletal muscle organ developmentGO:00605381630.013
negative regulation of lymphocyte activationGO:0051250910.013
morphogenesis of a branching epitheliumGO:00611381930.013
regulation of hormone levelsGO:00108172110.013
negative regulation of synapse assemblyGO:005196430.013
leukocyte migrationGO:00509001240.013
organic anion transportGO:00157111370.013
regulation of ossificationGO:00302781120.013
positive regulation of cell deathGO:00109422240.013
regulation of protein localizationGO:00328802310.013
central nervous system neuron differentiationGO:00219531620.013
regulation of smoothened signaling pathwayGO:0008589580.013
tube closureGO:0060606910.013
Mouse
striated muscle cell developmentGO:00550021250.013
heart contractionGO:0060047930.013
organelle assemblyGO:00709251770.013
tube formationGO:00351481400.013
Mouse
lateral inhibitionGO:004633110.013
regulation of response to woundingGO:19030341890.013
sequestering of metal ionGO:0051238190.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
erk1 and erk2 cascadeGO:0070371770.013
protein polymerizationGO:0051258570.013
Mouse
positive regulation of purine nucleotide catabolic processGO:0033123880.013
lymphocyte proliferationGO:00466511640.013
membrane organizationGO:00610242450.013
rna processingGO:00063961050.013
nuclear transportGO:00511691390.013
innate immune responseGO:00450871570.013
regulation of blood circulationGO:1903522930.013
protein processingGO:00164851630.013
axon guidanceGO:00074111410.013
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
circadian rhythmGO:00076231140.012
nucleocytoplasmic transportGO:00069131390.012
mitotic cell cycleGO:00002781950.012
spermatid developmentGO:00072861080.012
neuron deathGO:00709971540.012
axon target recognitionGO:000741240.012
b cell activationGO:00421131610.012
mesoderm developmentGO:00074981000.012
regulation of adaptive immune responseGO:0002819900.012
regulation of vesicle mediated transportGO:00606271390.012
multi multicellular organism processGO:00447061090.012
regulation of neuron differentiationGO:00456642810.012
negative regulation of hydrolase activityGO:0051346710.012
purine nucleotide biosynthetic processGO:0006164650.012
negative regulation of organelle organizationGO:0010639900.012
negative regulation of cell projection organizationGO:0031345560.012
negative regulation of ras protein signal transductionGO:0046580180.012
regulation of establishment of protein localizationGO:00702011810.012
response to organic cyclic compoundGO:00140701980.012
organelle localizationGO:00516401790.012
regulation of transmembrane transportGO:00347621280.012
canonical wnt signaling pathwayGO:00600701300.012
neuron migrationGO:00017641220.012
regulation of rho protein signal transductionGO:0035023710.012
mitotic cytokinesisGO:000028140.012
peptide hormone secretionGO:00300721090.012
rac protein signal transductionGO:0016601130.012
cyclic nucleotide metabolic processGO:0009187590.012
stem cell maintenanceGO:00198271300.012
smoothened signaling pathwayGO:00072241050.012
positive regulation of lymphocyte activationGO:00512511400.012
positive regulation of gtpase activityGO:0043547850.012
olfactory learningGO:000835520.011
renal system developmentGO:00720012250.011
neuron apoptotic processGO:00514021420.011
formation of organ boundaryGO:001016010.011
neuronal action potentialGO:0019228540.011
engulfment of apoptotic cellGO:004365230.011
regulation of lymphocyte differentiationGO:00456191070.011
negative regulation of cell cycleGO:00457861230.011
regulation of cytokine productionGO:00018172660.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
negative regulation of transferase activityGO:0051348850.011
learning or memoryGO:00076111480.011
urogenital system developmentGO:00016552610.011
anatomical structure homeostasisGO:00602491450.011
monosaccharide transportGO:0015749580.011
regulation of neuron deathGO:19012141340.011
cerebral cortex developmentGO:0021987860.011
cellular response to organonitrogen compoundGO:00714171450.011
response to oxidative stressGO:00069791230.011
exocytosisGO:00068871210.011
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.011
inorganic cation transmembrane transportGO:00986622070.011
regulation of protein complex assemblyGO:0043254830.011
Mouse
meiotic cell cycleGO:00513211220.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
regulation of bindingGO:00510981110.011
regulation of wnt signaling pathwayGO:00301111230.011
establishment of organelle localizationGO:00516561220.011
macromolecule methylationGO:00434141200.011
regulation of leukocyte proliferationGO:00706631210.011
rna interferenceGO:001624620.011
establishment or maintenance of cell polarityGO:0007163860.011
translationGO:0006412930.011
peptidyl tyrosine phosphorylationGO:00181081430.011
embryonic organ morphogenesisGO:00485622760.011
nucleoside phosphate biosynthetic processGO:1901293790.011
compound eye developmentGO:004874910.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
bmp signaling pathwayGO:0030509930.011
inorganic ion transmembrane transportGO:00986602340.011
cellular response to molecule of bacterial originGO:0071219830.011
regulation of cytoskeleton organizationGO:00514931220.011
Mouse
epidermis developmentGO:00085441870.011
skeletal system morphogenesisGO:00487052030.011
organophosphate biosynthetic processGO:00904071220.011
regulation of circadian rhythmGO:0042752580.011
regulation of cell adhesionGO:00301551540.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
response to acid chemicalGO:00011011110.010
connective tissue developmentGO:00614481790.010
cellular metal ion homeostasisGO:00068751510.010
regulation of protein catabolic processGO:00421761080.010
regulation of neuron apoptotic processGO:00435231220.010
response to light stimulusGO:00094161350.010
regulation of proteolysisGO:00301621640.010
neural tube closureGO:0001843900.010
Mouse
limb developmentGO:00601731660.010
amide transportGO:00428861380.010
muscle cell developmentGO:00550011330.010
regulation of cell cycle processGO:00105641600.010
organic hydroxy compound metabolic processGO:19016152030.010
positive regulation of nucleotide catabolic processGO:0030813880.010
glycoprotein biosynthetic processGO:0009101890.010
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.010
hexose transportGO:0008645560.010
positive regulation of apoptotic processGO:00430652170.010
heart processGO:0003015940.010
pallium developmentGO:00215431200.010
cognitionGO:00508901490.010
leukocyte mediated immunityGO:00024431740.010
actin polymerization or depolymerizationGO:0008154540.010
Mouse
lens development in camera type eyeGO:0002088620.010
regulation of secretion by cellGO:19035302490.010
metal ion homeostasisGO:00550651890.010

Spred2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.034
disease of anatomical entityDOID:700.034
central nervous system diseaseDOID:33100.020
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.019
organ system cancerDOID:005068600.019
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011