Mus musculus

79 known processes

Pik3r3

phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)

(Aliases: p55pik,AA414954)

Pik3r3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
phosphatidylinositol phosphorylationGO:0046854230.637
regulation of zinc ion transportGO:007157920.417
lipid phosphorylationGO:0046834250.406
regulation of zinc ion transmembrane transportGO:007158020.202
glycerophospholipid biosynthetic processGO:0046474320.201
glycerolipid biosynthetic processGO:0045017500.197
negative regulation of zinc ion transmembrane transportGO:007158320.166
phospholipid biosynthetic processGO:0008654360.155
positive regulation of cellular amino acid metabolic processGO:004576430.131
transmembrane transportGO:00550854120.123
positive regulation of cellular amine metabolic processGO:003324050.098
negative regulation of fibroblast apoptotic processGO:200027060.097
glycerophospholipid metabolic processGO:0006650710.093
organic cyclic compound catabolic processGO:19013612950.087
nucleotide metabolic processGO:00091173320.086
dna modificationGO:0006304500.085
regulation of cellular amino acid metabolic processGO:000652150.085
phosphatidylinositol 3 phosphate biosynthetic processGO:003609260.081
regulation of cellular amine metabolic processGO:0033238200.075
dna metabolic processGO:00062593030.073
nucleobase containing small molecule metabolic processGO:00550863520.071
cellular amine metabolic processGO:0044106440.069
carbohydrate derivative catabolic processGO:19011362310.068
cellular ketone metabolic processGO:0042180840.068
regulation of dna methylationGO:0044030120.067
synaptic transmissionGO:00072683290.067
purine ribonucleoside metabolic processGO:00461282410.067
amine metabolic processGO:0009308450.067
cellular amino acid metabolic processGO:00065201030.067
microtubule based processGO:00070172360.066
cation transmembrane transportGO:00986552660.066
aromatic compound catabolic processGO:00194392860.065
phospholipid metabolic processGO:0006644870.060
transition metal ion transportGO:0000041380.060
regulation of genetic imprintingGO:200065350.060
inorganic ion transmembrane transportGO:00986602340.059
purine nucleotide catabolic processGO:00061952110.058
organonitrogen compound catabolic processGO:19015652640.058
glycosyl compound metabolic processGO:19016572460.057
regulation of cellular ketone metabolic processGO:0010565660.054
cell substrate adhesionGO:00315891300.052
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.052
purine nucleoside triphosphate catabolic processGO:00091462030.052
small gtpase mediated signal transductionGO:0007264970.051
ribonucleotide catabolic processGO:00092612080.050
positive regulation of protein modification processGO:00314012990.049
glucose metabolic processGO:0006006920.049
purine ribonucleotide metabolic processGO:00091502900.049
ribonucleotide metabolic processGO:00092592910.047
ribonucleoside catabolic processGO:00424542060.046
glycerolipid metabolic processGO:00464861220.046
regulation of transferase activityGO:00513382630.046
methylationGO:00322591340.044
inorganic cation transmembrane transportGO:00986622070.044
cellular homeostasisGO:00197252400.042
dna alkylationGO:0006305430.042
ribose phosphate metabolic processGO:00196932910.042
organophosphate biosynthetic processGO:00904071220.041
carbohydrate metabolic processGO:00059752300.041
macromolecule catabolic processGO:00090572810.041
ion transmembrane transportGO:00342203610.040
genetic imprintingGO:0071514270.040
neuron deathGO:00709971540.040
cellular component assembly involved in morphogenesisGO:00109271390.040
organophosphate catabolic processGO:00464342320.040
lipid biosynthetic processGO:00086101790.040
macromolecule methylationGO:00434141200.039
actin cytoskeleton organizationGO:00300362200.039
ribonucleoside metabolic processGO:00091192450.039
cell adhesionGO:00071553290.039
Mouse
gtp catabolic processGO:00061841430.039
negative regulation of zinc ion transportGO:007158220.038
positive regulation of protein phosphorylationGO:00019342420.038
cognitionGO:00508901490.038
germ cell developmentGO:00072811850.038
regulation of neuron projection developmentGO:00109751690.038
regulation of translationGO:0006417710.038
cation transportGO:00068123990.038
regulation of organelle organizationGO:00330432890.037
ribonucleoside triphosphate metabolic processGO:00091992200.037
regulation of cell projection organizationGO:00313442060.037
glycosyl compound catabolic processGO:19016582060.037
cation homeostasisGO:00550802120.037
response to light stimulusGO:00094161350.036
Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.036
nucleoside phosphate metabolic processGO:00067533380.035
muscle cell differentiationGO:00426922610.035
dna methylationGO:0006306430.035
positive regulation of transferase activityGO:00513471670.035
negative regulation of cellular protein metabolic processGO:00322692470.034
protein ubiquitinationGO:00165671710.034
cell divisionGO:00513011200.033
positive regulation of neuron differentiationGO:00456661410.033
homeostasis of number of cellsGO:00488722100.032
protein modification by small protein conjugationGO:00324461870.032
purine ribonucleoside catabolic processGO:00461302050.032
purine ribonucleotide catabolic processGO:00091542080.032
response to radiationGO:00093141650.032
Mouse
regulation of cell substrate adhesionGO:0010810730.032
Mouse
modification dependent protein catabolic processGO:00199411330.032
hexose metabolic processGO:0019318980.032
cellular chemical homeostasisGO:00550822150.031
zinc ion transmembrane transportGO:0071577100.031
regulation of nucleoside metabolic processGO:00091181300.031
dna hypomethylationGO:004402810.031
apoptotic signaling pathwayGO:00971903060.031
Mouse
regulation of hydrolase activityGO:00513362460.031
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.031
coagulationGO:0050817780.030
organelle assemblyGO:00709251770.030
nucleoside phosphate catabolic processGO:19012922220.030
negative regulation of protein metabolic processGO:00512482820.030
wound healingGO:00420601570.030
purine ribonucleoside triphosphate catabolic processGO:00092071990.030
neuron apoptotic processGO:00514021420.029
regulation of transmembrane transportGO:00347621280.029
regulation of cell migrationGO:00303342190.029
Mouse
regulation of kinase activityGO:00435492490.029
positive regulation of purine nucleotide metabolic processGO:19005441140.029
immune effector processGO:00022523210.029
negative regulation of cell proliferationGO:00082852960.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.029
regulation of cell adhesionGO:00301551540.029
Mouse
peptidyl serine modificationGO:0018209830.028
phosphatidylinositol metabolic processGO:0046488450.028
regulation of cell cycleGO:00517262810.028
regulation of apoptotic signaling pathwayGO:20012331970.028
rho protein signal transductionGO:0007266320.028
cellular lipid metabolic processGO:00442553230.028
negative regulation of cellular component organizationGO:00511291940.028
positive regulation of cellular catabolic processGO:00313311480.028
regulation of metal ion transportGO:00109591060.027
divalent inorganic cation homeostasisGO:00725071380.027
positive regulation of protein kinase activityGO:00458601440.027
actin filament organizationGO:00070151130.027
muscle cell developmentGO:00550011330.027
protein localization to organelleGO:00333651850.027
Mouse
regulation of neuron deathGO:19012141340.027
translationGO:0006412930.027
peptidyl amino acid modificationGO:00181933360.027
regulation of body fluid levelsGO:00508781620.026
response to insulinGO:00328681000.026
cellular protein catabolic processGO:00442571550.026
developmental maturationGO:00217001930.026
guanosine containing compound catabolic processGO:19010691440.026
monosaccharide metabolic processGO:00059961060.026
regulation of ion transmembrane transportGO:00347651190.026
metal ion homeostasisGO:00550651890.026
blood coagulationGO:0007596760.025
learning or memoryGO:00076111480.025
protein modification by small protein conjugation or removalGO:00706472070.025
microtubule cytoskeleton organizationGO:00002261570.025
regulation of purine nucleotide catabolic processGO:00331211220.025
cilium morphogenesisGO:00602711020.024
purine nucleoside metabolic processGO:00422782410.024
regulation of ras protein signal transductionGO:00465781140.024
compound eye developmentGO:004874910.024
muscle tissue developmentGO:00605373080.024
cell cell adhesionGO:0098609410.024
purine containing compound metabolic processGO:00725213110.024
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.024
nucleoside metabolic processGO:00091162460.024
regulation of purine nucleotide metabolic processGO:19005421690.024
nucleoside triphosphate metabolic processGO:00091412300.023
regulation of cell motilityGO:20001452360.023
Mouse
cellular metal ion homeostasisGO:00068751510.023
regulation of neuron apoptotic processGO:00435231220.023
regulation of protein kinase activityGO:00458592320.023
endomembrane system organizationGO:00102561470.022
mitotic cell cycleGO:00002781950.022
purine nucleotide metabolic processGO:00061633020.022
g protein coupled receptor signaling pathwayGO:00071862430.022
multicellular organism growthGO:00352641610.022
negative regulation of immune system processGO:00026832090.022
Mouse
platelet activationGO:0030168400.021
b cell activationGO:00421131610.021
Mouse
spermatid differentiationGO:00485151150.021
rac protein signal transductionGO:0016601130.021
heterocycle catabolic processGO:00467002800.021
cellular macromolecule catabolic processGO:00442652060.021
protein complex disassemblyGO:0043241400.021
purine containing compound catabolic processGO:00725232130.020
regulation of synaptic growth at neuromuscular junctionGO:000858240.020
hypomethylation of cpg islandGO:004402910.020
positive regulation of peptidyl serine phosphorylationGO:0033138250.020
cytokine productionGO:00018163190.020
Mouse
ubiquitin dependent protein catabolic processGO:00065111290.020
regulation of cellular catabolic processGO:00313292420.020
positive regulation of cell developmentGO:00107202370.020
cellular response to lipidGO:00713961450.020
regulation of cell morphogenesis involved in differentiationGO:00107691510.020
morphogenesis of embryonic epitheliumGO:00163311590.020
oocyte axis specificationGO:000730920.020
spermatid developmentGO:00072861080.020
exocytosisGO:00068871210.020
lipid modificationGO:0030258650.020
regulation of synaptic plasticityGO:0048167870.020
cell type specific apoptotic processGO:00972852680.020
muscle system processGO:00030121410.020
cellular nitrogen compound catabolic processGO:00442702800.019
synapse organizationGO:00508081250.019
striated muscle cell developmentGO:00550021250.019
negative regulation of organelle organizationGO:0010639900.019
protein depolymerizationGO:0051261340.019
nucleoside triphosphate catabolic processGO:00091432050.019
regulation of cellular component sizeGO:00325351210.019
Fly
t cell activationGO:00421102890.019
proteolysis involved in cellular protein catabolic processGO:00516031470.019
response to growth factorGO:00708481980.019
neural tube developmentGO:00219151600.018
cellular ion homeostasisGO:00068731650.018
neuronal action potentialGO:0019228540.018
positive regulation of cell deathGO:00109422240.018
positive regulation of purine nucleotide catabolic processGO:0033123880.018
regulation of vesicle mediated transportGO:00606271390.018
regulation of cytokine productionGO:00018172660.018
Mouse
axonogenesisGO:00074092740.018
nucleotide catabolic processGO:00091662170.018
protein catabolic processGO:00301632210.018
positive regulation of cell projection organizationGO:0031346950.018
gland developmentGO:00487323300.018
purine ribonucleoside triphosphate metabolic processGO:00092052200.018
male gamete generationGO:00482322850.018
myotube differentiationGO:00149021050.018
regulation of actin filament based processGO:0032970990.017
positive regulation of cell motilityGO:20001471160.017
Mouse
membrane organizationGO:00610242450.017
positive regulation of gtpase activityGO:0043547850.017
negative regulation of neuron deathGO:1901215980.017
nucleoside catabolic processGO:00091642060.017
negative regulation of cytoskeleton organizationGO:0051494360.017
peptidyl serine phosphorylationGO:0018105740.017
positive regulation of kinase activityGO:00336741550.017
lymphocyte differentiationGO:00300982420.017
Mouse
embryonic epithelial tube formationGO:00018381300.017
nitrogen compound transportGO:00717052710.017
carbohydrate derivative biosynthetic processGO:19011371830.017
calcium ion homeostasisGO:00550741270.017
positive regulation of programmed cell deathGO:00430682180.017
digestive tract developmentGO:00485651900.017
intracellular protein transportGO:00068862040.016
Mouse
rap protein signal transductionGO:003248630.016
purine nucleoside catabolic processGO:00061522050.016
retina development in camera type eyeGO:00600411190.016
protein targetingGO:00066051430.016
Mouse
positive regulation of apoptotic processGO:00430652170.016
fat cell differentiationGO:00454441600.016
negative regulation of transmembrane transportGO:0034763150.016
positive regulation of growthGO:00459271040.016
positive regulation of nucleotide catabolic processGO:0030813880.016
macromolecular complex disassemblyGO:0032984430.016
regulation of secretionGO:00510462740.015
glucose homeostasisGO:00425931280.015
regulation of proteolysisGO:00301621640.015
cellular response to organonitrogen compoundGO:00714171450.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
positive regulation of gtp catabolic processGO:0033126850.015
response to inorganic substanceGO:0010035960.015
transmission of nerve impulseGO:0019226760.015
negative regulation of leukocyte differentiationGO:1902106510.015
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.015
photoreceptor cell morphogenesisGO:000859430.015
activation of adenylate cyclase activityGO:000719040.015
negative regulation of neuron apoptotic processGO:0043524920.015
cellular protein complex assemblyGO:00436231160.015
pole plasm assemblyGO:000731520.015
regulation of cell sizeGO:0008361720.015
Fly
chromatin organizationGO:00063252060.015
response to peptide hormoneGO:00434341270.015
cellular response to hormone stimulusGO:00328701500.015
regulation of peptidyl serine phosphorylationGO:0033135390.015
cellular carbohydrate metabolic processGO:00442621190.015
posttranscriptional regulation of gene expressionGO:00106081550.015
cellular protein complex disassemblyGO:0043624360.015
engulfment of apoptotic cellGO:004365230.014
positive regulation of ras gtpase activityGO:0032320650.014
regulation of cytoskeleton organizationGO:00514931220.014
t cell differentiationGO:00302171740.014
actin polymerization or depolymerizationGO:0008154540.014
protein maturationGO:00516041760.014
regulation of nucleotide metabolic processGO:00061401690.014
morphogenesis of a branching epitheliumGO:00611381930.014
neural tube formationGO:00018411080.014
regulation of ion transportGO:00432692150.014
smoothened signaling pathwayGO:00072241050.014
negative regulation of cell developmentGO:00107211690.014
actin filament polymerizationGO:0030041440.014
leukocyte differentiationGO:00025213420.014
Mouse
peptidyl tyrosine phosphorylationGO:00181081430.014
organelle fissionGO:00482851700.013
regulation of anatomical structure sizeGO:00900661780.013
Fly
regulation of leukocyte differentiationGO:19021051590.013
Mouse
adult behaviorGO:00305341350.013
regulation of cellular component biogenesisGO:00440871810.013
myeloid cell differentiationGO:00300992330.013
Mouse
male genitalia morphogenesisGO:004880840.013
establishment or maintenance of cytoskeleton polarityGO:003095220.013
negative regulation of cellular catabolic processGO:0031330470.013
chemotaxisGO:00069352470.013
cellular response to growth factor stimulusGO:00713631970.013
cilium assemblyGO:0042384810.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
epithelial cell proliferationGO:00506731740.013
oocyte constructionGO:000730820.013
positive regulation of nucleoside metabolic processGO:0045979910.013
viral gene expressionGO:001908030.013
negative regulation of protein complex disassemblyGO:0043242220.013
wnt signaling pathwayGO:00160551880.013
mrna metabolic processGO:0016071840.013
forebrain developmentGO:00309003020.013
cell growthGO:00160491300.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
stem cell differentiationGO:00488632680.012
negative regulation of synapse assemblyGO:005196430.012
localization within membraneGO:005166840.012
oogenesisGO:0048477560.012
gastrulationGO:00073691160.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
epithelial tube formationGO:00721751300.012
regulation of cell growthGO:0001558910.012
myelinationGO:0042552740.012
inflammatory responseGO:00069542440.012
negative regulation of anoikisGO:200081120.012
axon ensheathmentGO:0008366760.012
learningGO:0007612980.012
regulation of anoikisGO:200020920.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
regulation of protein complex disassemblyGO:0043244280.012
peptide transportGO:00158331330.012
cellular calcium ion homeostasisGO:00068741190.012
positive regulation of intracellular transportGO:0032388700.012
retrograde transport endosome to golgiGO:004214720.012
transforming growth factor beta receptor signaling pathwayGO:0007179710.012
camera type eye developmentGO:00430102660.012
glycoprotein metabolic processGO:00091001160.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
nucleocytoplasmic transportGO:00069131390.012
Mouse
microtubule based movementGO:0007018840.012
multicellular organismal signalingGO:0035637910.011
gonad morphogenesisGO:003526210.011
tube formationGO:00351481400.011
multi multicellular organism processGO:00447061090.011
negative regulation of cell motilityGO:2000146610.011
reactive oxygen species metabolic processGO:0072593840.011
cellular response to organic cyclic compoundGO:0071407870.011
regulation of multi organism processGO:00439001110.011
regulation of neuronal synaptic plasticityGO:0048168300.011
muscle fiber developmentGO:0048747760.011
cytoplasmic transportGO:00164822340.011
Mouse
carbohydrate homeostasisGO:00335001280.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
spermatogenesisGO:00072832840.011
lung developmentGO:00303241640.011
negative regulation of molecular functionGO:00440922580.011
developmental growth involved in morphogenesisGO:00605601380.011
regulation of mitotic cell cycleGO:00073461260.011
tube closureGO:0060606910.011
skeletal muscle organ developmentGO:00605381630.011
leukocyte mediated immunityGO:00024431740.011
regulation of lymphocyte activationGO:00512492400.011
photoreceptor cell differentiationGO:0046530520.011
pallium developmentGO:00215431200.011
negative regulation of protein depolymerizationGO:1901880210.011
maternal determination of anterior posterior axis embryoGO:000835820.011
connective tissue developmentGO:00614481790.011
proteasomal protein catabolic processGO:0010498980.011
renal system developmentGO:00720012250.011
regulation of protein depolymerizationGO:1901879260.011
regulation of t cell activationGO:00508631700.011
regulation of microtubule based processGO:0032886520.011
microtubule based transportGO:0010970500.011
protein kinase b signalingGO:0043491740.011
morphogenesis of a branching structureGO:00017632030.011
dendritic spine organizationGO:0097061260.011
sensory perceptionGO:00076002450.011
primary neural tube formationGO:0014020950.011
blood circulationGO:00080151950.011
skeletal system morphogenesisGO:00487052030.011
positive regulation of cell migrationGO:00303351090.011
Mouse
myeloid leukocyte differentiationGO:00025731190.011
Mouse
positive regulation of ubiquitin protein transferase activityGO:005144340.011
lateral inhibitionGO:004633110.011
negative regulation of ion transportGO:0043271280.011
regulation of fibroblast apoptotic processGO:200026980.010
male sex differentiationGO:00466611090.010
cyclic nucleotide metabolic processGO:0009187590.010
interspecies interaction between organismsGO:0044419830.010
b cell homeostasisGO:0001782340.010
regulation of striated muscle cell differentiationGO:0051153810.010
regulation of nucleotide catabolic processGO:00308111220.010
regulation of hormone levelsGO:00108172110.010
locomotory behaviorGO:00076261950.010
inclusion body assemblyGO:007084130.010
respiratory tube developmentGO:00303231670.010
myosin filament assemblyGO:003103420.010
peptide secretionGO:00027901140.010
fibroblast apoptotic processGO:004434690.010
ear developmentGO:00435832000.010
regulation of viral transcriptionGO:004678230.010
male anatomical structure morphogenesisGO:009059840.010
viral transcriptionGO:001908330.010
response to nutrient levelsGO:00316671090.010
regulation of bindingGO:00510981110.010

Pik3r3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.032
cancerDOID:16200.032
organ system cancerDOID:005068600.032
thoracic cancerDOID:509300.032
integumentary system diseaseDOID:1600.029
disease of anatomical entityDOID:700.029
breast cancerDOID:161200.021
gastrointestinal system cancerDOID:311900.018
large intestine cancerDOID:567200.018
intestinal cancerDOID:1015500.018
colon cancerDOID:21900.018
colorectal cancerDOID:925600.018
immune system diseaseDOID:291400.015
nervous system diseaseDOID:86300.014
colon carcinomaDOID:152000.013
central nervous system diseaseDOID:33100.011