IMP: Integrative Multi-species Prediction

Mus musculus

33 known processes

Pik3r2

phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)

(Aliases: p85beta)

Ensembl: ENSMUSG00000031834
Entrez: 18709
UniProtKB: O08908

Process Predictions
Disease Predictions

Pik3r2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of cellular ketone metabolic process	GO:0010565	66	0.362
cellular lipid metabolic process	GO:0044255	323	0.312
cellular ketone metabolic process	GO:0042180	84	0.202
skeletal system development	GO:0001501	356	0.178
lipid biosynthetic process	GO:0008610	179	0.169
synaptic transmission	GO:0007268	329	0.142
purine ribonucleotide metabolic process	GO:0009150	290	0.142
antimicrobial peptide production	GO:0002775	2	0.131
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.127
purine nucleoside catabolic process	GO:0006152	205	0.117
regulation of nucleotide metabolic process	GO:0006140	169	0.115
male gamete generation	GO:0048232	285	0.110
ribonucleotide metabolic process	GO:0009259	291	0.109
small gtpase mediated signal transduction	GO:0007264	97	0.106
ras protein signal transduction	GO:0007265	77	0.104
regulation of organelle organization	GO:0033043	289	0.102
vesicle localization	GO:0051648	86	0.098
glycerolipid biosynthetic process	GO:0045017	50	0.096
nucleobase containing small molecule metabolic process	GO:0055086	352	0.093
monocarboxylic acid metabolic process	GO:0032787	191	0.093
phospholipid biosynthetic process	GO:0008654	36	0.087
carbohydrate metabolic process	GO:0005975	230	0.085
nucleotide metabolic process	GO:0009117	332	0.085
regulation of cellular amine metabolic process	GO:0033238	20	0.084
regulation of nucleotide catabolic process	GO:0030811	122	0.083
rho protein signal transduction	GO:0007266	32	0.083
sulfur compound biosynthetic process	GO:0044272	37	0.080
organophosphate biosynthetic process	GO:0090407	122	0.080
connective tissue development	GO:0061448	179	0.079
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.078	Mouse Worm
establishment of organelle localization	GO:0051656	122	0.078
ribonucleotide catabolic process	GO:0009261	208	0.078
carbohydrate derivative biosynthetic process	GO:1901137	183	0.076
lysosome organization	GO:0007040	21	0.076
regulation of lipid metabolic process	GO:0019216	118	0.074	Mouse Fly
regulation of homeostatic process	GO:0032844	182	0.072
synaptic vesicle localization	GO:0097479	59	0.072
organophosphate catabolic process	GO:0046434	232	0.072
aromatic compound catabolic process	GO:0019439	286	0.071
spermatogenesis	GO:0007283	284	0.071
phospholipid metabolic process	GO:0006644	87	0.071
regulation of antimicrobial peptide biosynthetic process	GO:0002805	1	0.069
regulation of neuron differentiation	GO:0045664	281	0.068
organelle localization	GO:0051640	179	0.065
gtp catabolic process	GO:0006184	143	0.064
purine nucleotide metabolic process	GO:0006163	302	0.064
organonitrogen compound biosynthetic process	GO:1901566	192	0.062
histone modification	GO:0016570	159	0.062
glycosyl compound metabolic process	GO:1901657	246	0.061
phosphatidic acid biosynthetic process	GO:0006654	2	0.061
fatty acid metabolic process	GO:0006631	121	0.060
cellular response to extracellular stimulus	GO:0031668	81	0.059
protein targeting	GO:0006605	143	0.059	Mouse
regulation of nucleoside metabolic process	GO:0009118	130	0.058
carbohydrate homeostasis	GO:0033500	128	0.058
glycerophospholipid biosynthetic process	GO:0046474	32	0.057
nitrogen compound transport	GO:0071705	271	0.057
amine metabolic process	GO:0009308	45	0.056
intracellular protein transport	GO:0006886	204	0.056	Mouse
establishment of protein localization to organelle	GO:0072594	118	0.054	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.053
endomembrane system organization	GO:0010256	147	0.053
regulation of fatty acid metabolic process	GO:0019217	28	0.051
regulation of neuron projection development	GO:0010975	169	0.051
regulation of epithelial cell proliferation	GO:0050678	141	0.050
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.049
glycosyl compound catabolic process	GO:1901658	206	0.049
cytoplasmic transport	GO:0016482	234	0.049	Mouse
nucleoside metabolic process	GO:0009116	246	0.048
fertilization	GO:0009566	127	0.047
cellular amino acid metabolic process	GO:0006520	103	0.047
positive regulation of cellular amine metabolic process	GO:0033240	5	0.046
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	GO:1900740	3	0.046
lytic vacuole organization	GO:0080171	21	0.046
regulation of cellular amino acid metabolic process	GO:0006521	5	0.046
chromatin organization	GO:0006325	206	0.045
regulation of apoptotic signaling pathway	GO:2001233	197	0.045
posttranscriptional regulation of gene expression	GO:0010608	155	0.044
mitochondrial outer membrane permeabilization involved in programmed cell death	GO:1902686	11	0.044
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.043
lipid homeostasis	GO:0055088	63	0.043
multi multicellular organism process	GO:0044706	109	0.042
sensory perception	GO:0007600	245	0.042
neural tube development	GO:0021915	160	0.041
positive regulation of organelle organization	GO:0010638	128	0.041
positive regulation of protein modification process	GO:0031401	299	0.041
glycerolipid metabolic process	GO:0046486	122	0.041
cellular response to nutrient levels	GO:0031669	64	0.041
small molecule biosynthetic process	GO:0044283	132	0.040
guanosine containing compound metabolic process	GO:1901068	144	0.040
homeostasis of number of cells	GO:0048872	210	0.040
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.040
antimicrobial peptide biosynthetic process	GO:0002777	2	0.039
purine containing compound catabolic process	GO:0072523	213	0.039
muscle cell differentiation	GO:0042692	261	0.039
positive regulation of cell development	GO:0010720	237	0.039
endocytosis	GO:0006897	168	0.038
nucleoside phosphate metabolic process	GO:0006753	338	0.038
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.038
forebrain development	GO:0030900	302	0.038
glycoprotein biosynthetic process	GO:0009101	89	0.038
response to extracellular stimulus	GO:0009991	127	0.038
regulation of protein localization	GO:0032880	231	0.038
nucleoside triphosphate metabolic process	GO:0009141	230	0.038
ribonucleoside catabolic process	GO:0042454	206	0.038
protein localization to nucleus	GO:0034504	121	0.037	Mouse
epithelial cell proliferation	GO:0050673	174	0.037
regulation of vesicle mediated transport	GO:0060627	139	0.037
cellular nitrogen compound catabolic process	GO:0044270	280	0.037
positive regulation of mapk cascade	GO:0043410	170	0.036
regulation of secretion	GO:0051046	274	0.036
response to starvation	GO:0042594	65	0.036
cognition	GO:0050890	149	0.035
cellular response to cytokine stimulus	GO:0071345	189	0.035
purine ribonucleoside metabolic process	GO:0046128	241	0.035
regulation of transferase activity	GO:0051338	263	0.035	Mouse Fly
response to nutrient levels	GO:0031667	109	0.034
nucleoside phosphate catabolic process	GO:1901292	222	0.034
telencephalon development	GO:0021537	186	0.034
synaptic vesicle transport	GO:0048489	57	0.034
regulation of antimicrobial peptide production	GO:0002784	1	0.034
cellular amine metabolic process	GO:0044106	44	0.033
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.033
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.033
response to light stimulus	GO:0009416	135	0.033	Mouse
positive regulation of nucleotide metabolic process	GO:0045981	114	0.033
glucose homeostasis	GO:0042593	128	0.033
respiratory system development	GO:0060541	190	0.033
phosphatidic acid metabolic process	GO:0046473	2	0.033
regulation of purine nucleotide metabolic process	GO:1900542	169	0.032
regulation of ras protein signal transduction	GO:0046578	114	0.032
regulation of lipid biosynthetic process	GO:0046890	54	0.032
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.032
appendage development	GO:0048736	166	0.032
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.032
cation homeostasis	GO:0055080	212	0.031
tissue homeostasis	GO:0001894	115	0.031
purine ribonucleotide catabolic process	GO:0009154	208	0.031
protein import into nucleus	GO:0006606	95	0.031	Mouse
gland development	GO:0048732	330	0.030
synaptic vesicle recycling	GO:0036465	19	0.030
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.030
ribose phosphate metabolic process	GO:0019693	291	0.030
sterol homeostasis	GO:0055092	45	0.030
learning or memory	GO:0007611	148	0.030
microtubule based process	GO:0007017	236	0.030
ion transmembrane transport	GO:0034220	361	0.029
bone development	GO:0060348	120	0.029
peptidyl amino acid modification	GO:0018193	336	0.029
regulation of mapk cascade	GO:0043408	248	0.029
regulation of antimicrobial humoral response	GO:0002759	3	0.029
regulation of multi organism process	GO:0043900	111	0.029
organonitrogen compound catabolic process	GO:1901565	264	0.029
cellular carbohydrate metabolic process	GO:0044262	119	0.028
establishment of synaptic vesicle localization	GO:0097480	57	0.028
cellular protein catabolic process	GO:0044257	155	0.028
carbohydrate derivative catabolic process	GO:1901136	231	0.028
skeletal muscle organ development	GO:0060538	163	0.028
regionalization	GO:0003002	337	0.028
nucleoside triphosphate catabolic process	GO:0009143	205	0.028
maintenance of location	GO:0051235	89	0.028
cytokine mediated signaling pathway	GO:0019221	115	0.028
cellular response to external stimulus	GO:0071496	88	0.027
heterocycle catabolic process	GO:0046700	280	0.027
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.027
smoothened signaling pathway	GO:0007224	105	0.027
ossification	GO:0001503	216	0.027
positive regulation of programmed cell death	GO:0043068	218	0.027
cellular response to lipid	GO:0071396	145	0.027
i kappab kinase nf kappab signaling	GO:0007249	85	0.027
regulation of endocytosis	GO:0030100	69	0.027
negative regulation of molecular function	GO:0044092	258	0.026
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.026
retrograde transport endosome to golgi	GO:0042147	2	0.026
positive regulation of translational initiation	GO:0045948	4	0.026
ameboidal type cell migration	GO:0001667	128	0.026
memory	GO:0007613	58	0.026
response to peptide	GO:1901652	136	0.026	Mouse Worm
multicellular organismal response to stress	GO:0033555	62	0.026
purine containing compound metabolic process	GO:0072521	311	0.026
response to molecule of bacterial origin	GO:0002237	143	0.026
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.026
cellular response to hormone stimulus	GO:0032870	150	0.026	Mouse Worm
metal ion homeostasis	GO:0055065	189	0.026
muscle tissue development	GO:0060537	308	0.025
regulation of protein kinase activity	GO:0045859	232	0.025
multicellular organismal homeostasis	GO:0048871	164	0.025
sulfur compound metabolic process	GO:0006790	100	0.025
acetylcholine transport	GO:0015870	2	0.025
protein oligomerization	GO:0051259	67	0.025
ribonucleoside metabolic process	GO:0009119	245	0.025
anion transport	GO:0006820	177	0.025
spermatid differentiation	GO:0048515	115	0.025
lipid localization	GO:0010876	126	0.025
regulation of cellular catabolic process	GO:0031329	242	0.025	Human
urogenital system development	GO:0001655	261	0.025
vacuole organization	GO:0007033	38	0.025
cellular response to starvation	GO:0009267	57	0.025
modification dependent protein catabolic process	GO:0019941	133	0.025
guanosine containing compound catabolic process	GO:1901069	144	0.025
regulation of gtp catabolic process	GO:0033124	113	0.024
positive regulation of cellular catabolic process	GO:0031331	148	0.024
regulation of erk1 and erk2 cascade	GO:0070372	71	0.024
digestive tract development	GO:0048565	190	0.023
gastrulation	GO:0007369	116	0.023
positive regulation of nucleotide catabolic process	GO:0030813	88	0.023
response to organonitrogen compound	GO:0010243	246	0.023	Mouse Worm
negative regulation of synapse assembly	GO:0051964	3	0.023
apoptotic signaling pathway	GO:0097190	306	0.023	Mouse
single organism nuclear import	GO:1902593	95	0.023	Mouse
response to denervation involved in regulation of muscle adaptation	GO:0014894	4	0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.023
positive regulation of protein phosphorylation	GO:0001934	242	0.023
blood vessel morphogenesis	GO:0048514	285	0.023
carbohydrate biosynthetic process	GO:0016051	74	0.023
nucleoside catabolic process	GO:0009164	206	0.023
gluconeogenesis	GO:0006094	39	0.023
skeletal system morphogenesis	GO:0048705	203	0.023
insulin receptor signaling pathway	GO:0008286	49	0.023	Mouse Worm
positive regulation of hydrolase activity	GO:0051345	148	0.022
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	GO:1901028	7	0.022
hindbrain development	GO:0030902	128	0.022
peptide transport	GO:0015833	133	0.022
cellular response to lipopolysaccharide	GO:0071222	77	0.022
nuclear transport	GO:0051169	139	0.022	Mouse
asymmetric neuroblast division	GO:0055059	1	0.022
synaptic vesicle endocytosis	GO:0048488	19	0.022
protein catabolic process	GO:0030163	221	0.022
hexose biosynthetic process	GO:0019319	39	0.022
cell type specific apoptotic process	GO:0097285	268	0.022
peptidyl lysine modification	GO:0018205	77	0.022
organic acid biosynthetic process	GO:0016053	86	0.022
multicellular organism growth	GO:0035264	161	0.021
amide transport	GO:0042886	138	0.021
metencephalon development	GO:0022037	89	0.021
respiratory tube development	GO:0030323	167	0.021
purine nucleotide catabolic process	GO:0006195	211	0.021
establishment of vesicle localization	GO:0051650	81	0.021
organ growth	GO:0035265	117	0.021
transmembrane transport	GO:0055085	412	0.021
germ cell development	GO:0007281	185	0.021
regulation of secretion by cell	GO:1903530	249	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.021
cellular response to acid chemical	GO:0071229	68	0.021
regulation of mitochondrial membrane permeability	GO:0046902	17	0.021
mitotic cell cycle	GO:0000278	195	0.021
inorganic ion transmembrane transport	GO:0098660	234	0.021
membrane organization	GO:0061024	245	0.021
protein localization to organelle	GO:0033365	185	0.021	Mouse
regulation of chromosome organization	GO:0033044	83	0.020
regulation of humoral immune response	GO:0002920	22	0.020
regulation of proteolysis	GO:0030162	164	0.020
response to acid chemical	GO:0001101	111	0.020
macromolecule catabolic process	GO:0009057	281	0.020
purine nucleoside metabolic process	GO:0042278	241	0.020
covalent chromatin modification	GO:0016569	163	0.020
peptidyl serine phosphorylation	GO:0018105	74	0.020
glycosylation	GO:0070085	62	0.020
regulation of cell cycle	GO:0051726	281	0.020
embryonic placenta development	GO:0001892	98	0.019
regulation of establishment of protein localization	GO:0070201	181	0.019
positive regulation of protein kinase activity	GO:0045860	144	0.019
cellular homeostasis	GO:0019725	240	0.019
positive regulation of intracellular transport	GO:0032388	70	0.019
regulation of mitotic cell cycle	GO:0007346	126	0.019
cell junction organization	GO:0034330	77	0.019
regulation of cell projection organization	GO:0031344	206	0.019
apoptotic mitochondrial changes	GO:0008637	48	0.019
positive regulation of smoothened signaling pathway	GO:0045880	23	0.019
glycoprotein metabolic process	GO:0009100	116	0.019
negative regulation of cellular protein metabolic process	GO:0032269	247	0.019
regulation of cell migration	GO:0030334	219	0.019	Mouse
anion transmembrane transport	GO:0098656	71	0.019
regulation of protein maturation	GO:1903317	96	0.019
epithelial tube formation	GO:0072175	130	0.019
regulation of peptide transport	GO:0090087	91	0.019
intracellular receptor signaling pathway	GO:0030522	74	0.019
organic cyclic compound catabolic process	GO:1901361	295	0.019
angiogenesis	GO:0001525	201	0.018
immune effector process	GO:0002252	321	0.018
regulation of purine nucleotide catabolic process	GO:0033121	122	0.018
regulation of kinase activity	GO:0043549	249	0.018	Mouse Fly
protein import	GO:0017038	101	0.018	Mouse
protein localization to membrane	GO:0072657	108	0.018
striated muscle tissue development	GO:0014706	293	0.018
neural tube closure	GO:0001843	90	0.018
kidney development	GO:0001822	213	0.018
negative regulation of cell cycle	GO:0045786	123	0.018
chemotaxis	GO:0006935	247	0.018
cell adhesion	GO:0007155	329	0.018	Mouse
hexose metabolic process	GO:0019318	98	0.018
regulation of reproductive process	GO:2000241	66	0.018
tube formation	GO:0035148	140	0.018
positive regulation of cell death	GO:0010942	224	0.018
regulation of hydrolase activity	GO:0051336	246	0.018
jnk cascade	GO:0007254	72	0.018
protein targeting to peroxisome	GO:0006625	4	0.018
synapsis	GO:0007129	34	0.018
mapk cascade	GO:0000165	281	0.018
positive regulation of stress activated mapk cascade	GO:0032874	48	0.018
muscle system process	GO:0003012	141	0.017
cholesterol homeostasis	GO:0042632	44	0.017
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.017
peptidyl serine modification	GO:0018209	83	0.017
positive regulation of cell cycle	GO:0045787	92	0.017
internal protein amino acid acetylation	GO:0006475	42	0.017
bone morphogenesis	GO:0060349	78	0.017
stress activated protein kinase signaling cascade	GO:0031098	81	0.017
translation	GO:0006412	93	0.017
mucopolysaccharide metabolic process	GO:1903510	25	0.017
cellular ion homeostasis	GO:0006873	165	0.017
regulation of membrane potential	GO:0042391	192	0.017
regulation of hormone secretion	GO:0046883	88	0.017
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.017
positive regulation of kinase activity	GO:0033674	155	0.017
regulation of protein serine threonine kinase activity	GO:0071900	157	0.017
developmental maturation	GO:0021700	193	0.017
positive regulation of secretion	GO:0051047	130	0.017
calcium ion homeostasis	GO:0055074	127	0.017
regulation of binding	GO:0051098	111	0.017
peptide biosynthetic process	GO:0043043	11	0.017
cartilage development	GO:0051216	140	0.017
placenta blood vessel development	GO:0060674	31	0.017
peptide secretion	GO:0002790	114	0.017
transmission of nerve impulse	GO:0019226	76	0.016
compound eye development	GO:0048749	1	0.016
acetate ester transport	GO:1901374	2	0.016
chromatin modification	GO:0016568	187	0.016
anatomical structure homeostasis	GO:0060249	145	0.016
protein acylation	GO:0043543	64	0.016
brain segmentation	GO:0035284	3	0.016
placenta development	GO:0001890	140	0.016
lipid modification	GO:0030258	65	0.016
negative regulation of cellular component organization	GO:0051129	194	0.016
tube closure	GO:0060606	91	0.016
reactive nitrogen species metabolic process	GO:2001057	0	0.016
regulation of carbohydrate biosynthetic process	GO:0043255	40	0.016
positive regulation of transferase activity	GO:0051347	167	0.016
neuron migration	GO:0001764	122	0.016
monosaccharide metabolic process	GO:0005996	106	0.016
response to oxidative stress	GO:0006979	123	0.016
rhythmic process	GO:0048511	174	0.016
organic anion transport	GO:0015711	137	0.016
locomotory behavior	GO:0007626	195	0.016
regulation of cellular response to stress	GO:0080135	159	0.016
cellular response to biotic stimulus	GO:0071216	92	0.016
camera type eye development	GO:0043010	266	0.016
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	GO:1901030	6	0.016
ribonucleotide biosynthetic process	GO:0009260	59	0.016
protein glycosylation	GO:0006486	55	0.016
erk1 and erk2 cascade	GO:0070371	77	0.015
bmp signaling pathway	GO:0030509	93	0.015
regulation of organ morphogenesis	GO:2000027	144	0.015
mammary gland epithelial cell proliferation	GO:0033598	24	0.015
cation transport	GO:0006812	399	0.015
cell junction maintenance	GO:0034331	4	0.015
spermatid development	GO:0007286	108	0.015
regulation of peptide secretion	GO:0002791	77	0.015
regulation of feeding behavior	GO:0060259	3	0.015
modification dependent macromolecule catabolic process	GO:0043632	133	0.015
gtp metabolic process	GO:0046039	144	0.015
habituation	GO:0046959	3	0.015
cellular response to organonitrogen compound	GO:0071417	145	0.015	Mouse Worm
response to transforming growth factor beta	GO:0071559	88	0.015
response to organic cyclic compound	GO:0014070	198	0.015
regulation of cellular component biogenesis	GO:0044087	181	0.015
regulation of translational initiation by iron	GO:0006447	2	0.015
microtubule cytoskeleton organization	GO:0000226	157	0.015
skin development	GO:0043588	220	0.015
negative regulation of neuron projection development	GO:0010977	50	0.015
embryonic skeletal system development	GO:0048706	120	0.015
oocyte axis specification	GO:0007309	2	0.015
regulation of cell motility	GO:2000145	236	0.015	Mouse
limb development	GO:0060173	166	0.015
stress activated mapk cascade	GO:0051403	80	0.015
cell substrate adhesion	GO:0031589	130	0.015	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.015
mammary gland epithelium development	GO:0061180	65	0.015
regulation of protein catabolic process	GO:0042176	108	0.015
histone acetylation	GO:0016573	41	0.015
cell growth	GO:0016049	130	0.015
neuron projection extension	GO:1990138	64	0.015
cytokine biosynthetic process	GO:0042089	68	0.014
membrane lipid metabolic process	GO:0006643	53	0.014
response to growth factor	GO:0070848	198	0.014
protein maturation	GO:0051604	176	0.014
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	GO:0060528	4	0.014
response to insulin	GO:0032868	100	0.014	Mouse Worm
photoreceptor cell differentiation	GO:0046530	52	0.014
regulation of mitochondrion organization	GO:0010821	27	0.014
single fertilization	GO:0007338	82	0.014
pallium development	GO:0021543	120	0.014
regulation of peptide hormone secretion	GO:0090276	75	0.014
cellular calcium ion homeostasis	GO:0006874	119	0.014
acylglycerol homeostasis	GO:0055090	16	0.014
organic acid transport	GO:0015849	101	0.014
regulation of cell adhesion	GO:0030155	154	0.014	Mouse
action potential	GO:0001508	78	0.014
positive regulation of cell projection organization	GO:0031346	95	0.014
regulation of cellular protein catabolic process	GO:1903362	61	0.014
cerebral cortex development	GO:0021987	86	0.014
cellular response to molecule of bacterial origin	GO:0071219	83	0.014
positive regulation of nucleoside metabolic process	GO:0045979	91	0.014
lung development	GO:0030324	164	0.014
neural tube formation	GO:0001841	108	0.014
blood circulation	GO:0008015	195	0.014
positive regulation of neuron projection development	GO:0010976	79	0.014
establishment of spindle localization	GO:0051293	19	0.014
regulation of hormone levels	GO:0010817	211	0.014
cellular response to parathyroid hormone stimulus	GO:0071374	2	0.014
leukocyte migration	GO:0050900	124	0.014
actin cytoskeleton organization	GO:0030036	220	0.014
cellular response to insulin stimulus	GO:0032869	78	0.013	Mouse Worm
calcium ion transmembrane transport	GO:0070588	85	0.013
digestive system development	GO:0055123	200	0.013
regulation of smoothened signaling pathway	GO:0008589	58	0.013
organic hydroxy compound metabolic process	GO:1901615	203	0.013
negative regulation of cell development	GO:0010721	169	0.013
learning	GO:0007612	98	0.013
humoral immune response	GO:0006959	57	0.013
chondrocyte differentiation	GO:0002062	72	0.013
regulation of anterior head development	GO:2000742	2	0.013
purine ribonucleoside catabolic process	GO:0046130	205	0.013
proteoglycan metabolic process	GO:0006029	38	0.013
activation of immune response	GO:0002253	138	0.013
negative regulation of phosphorus metabolic process	GO:0010563	184	0.013
cytokine production	GO:0001816	319	0.013	Mouse
multicellular organismal aging	GO:0010259	24	0.013	Worm
protein processing	GO:0016485	163	0.013
regulation of ph	GO:0006885	26	0.013
myeloid leukocyte migration	GO:0097529	57	0.013
cation transmembrane transport	GO:0098655	266	0.013
regulation of intracellular transport	GO:0032386	159	0.013
negative regulation of cell proliferation	GO:0008285	296	0.013
glycerophospholipid metabolic process	GO:0006650	71	0.013
circadian rhythm	GO:0007623	114	0.013
morphogenesis of embryonic epithelium	GO:0016331	159	0.013
aminoglycan biosynthetic process	GO:0006023	15	0.013
positive regulation of ras gtpase activity	GO:0032320	65	0.013
regulation of cytoskeleton organization	GO:0051493	122	0.013
triglyceride homeostasis	GO:0070328	15	0.013
response to inorganic substance	GO:0010035	96	0.013
leukocyte differentiation	GO:0002521	342	0.013	Mouse
positive regulation of stem cell proliferation	GO:2000648	59	0.013
carboxylic acid biosynthetic process	GO:0046394	86	0.013
ubiquitin dependent protein catabolic process	GO:0006511	129	0.013
hematopoietic progenitor cell differentiation	GO:0002244	143	0.013
cyclic nucleotide metabolic process	GO:0009187	59	0.012
asymmetric stem cell division	GO:0098722	3	0.012
regulation of cytokine production	GO:0001817	266	0.012	Mouse
regulation of peptidyl lysine acetylation	GO:2000756	22	0.012
negative regulation of growth	GO:0045926	99	0.012
cellular response to abiotic stimulus	GO:0071214	56	0.012	Mouse
inorganic cation transmembrane transport	GO:0098662	207	0.012
organic hydroxy compound biosynthetic process	GO:1901617	77	0.012
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.012
morphogenesis of a branching structure	GO:0001763	203	0.012
stem cell proliferation	GO:0072089	117	0.012
multicellular organismal signaling	GO:0035637	91	0.012
heart morphogenesis	GO:0003007	178	0.012
nucleoside phosphate biosynthetic process	GO:1901293	79	0.012
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	31	0.012
chromosome organization involved in meiosis	GO:0070192	39	0.012
regulation of jnk cascade	GO:0046328	62	0.012
mitochondrial membrane organization	GO:0007006	26	0.012
organic hydroxy compound transport	GO:0015850	93	0.012
cell chemotaxis	GO:0060326	81	0.012
peptidyl lysine acetylation	GO:0018394	45	0.012
negative regulation of nervous system development	GO:0051961	156	0.012
regulation of acetylcholine secretion neurotransmission	GO:0014056	2	0.012
meiotic cell cycle process	GO:1903046	77	0.012
monosaccharide biosynthetic process	GO:0046364	44	0.012
internal peptidyl lysine acetylation	GO:0018393	42	0.012
regulation of cell growth	GO:0001558	91	0.012
regulation of system process	GO:0044057	200	0.012
negative regulation of cell projection organization	GO:0031345	56	0.011
negative regulation of phosphate metabolic process	GO:0045936	184	0.011
response to reactive oxygen species	GO:0000302	56	0.011
embryonic epithelial tube formation	GO:0001838	130	0.011
peptide hormone secretion	GO:0030072	109	0.011
cell maturation	GO:0048469	127	0.011
positive regulation of cholesterol homeostasis	GO:2000189	2	0.011
response to lipopolysaccharide	GO:0032496	128	0.011
establishment of protein localization to membrane	GO:0090150	54	0.011
cardiocyte differentiation	GO:0035051	87	0.011
fatty acid biosynthetic process	GO:0006633	41	0.011
nuclear import	GO:0051170	95	0.011	Mouse
regulation of protein processing	GO:0070613	96	0.011
regulation of protein secretion	GO:0050708	82	0.011
lipid transport	GO:0006869	98	0.011

Pik3r2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
neuromuscular disease	DOID:440	0.026
nervous system disease	DOID:863	0.026
neuropathy	DOID:870	0.026
disease of anatomical entity	DOID:7	0.026
charcot marie tooth disease	DOID:10595	0.013

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