Mus musculus

138 known processes

Iqgap3

IQ motif containing GTPase activating protein 3

(Aliases: D030034H08,AI593484,MGC32192)

Iqgap3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle assemblyGO:00709251770.675
microtubule cytoskeleton organization involved in mitosisGO:190285040.635
male meiosisGO:0007140370.589
microtubule cytoskeleton organizationGO:00002261570.415
microtubule based processGO:00070172360.414
dna metabolic processGO:00062593030.391
spindle assembly involved in mitosisGO:009030740.367
regulation of chromosome organizationGO:0033044830.358
regulation of cell cycleGO:00517262810.352
regulation of organelle organizationGO:00330432890.325
mitotic chromosome condensationGO:000707610.290
regulation of cell cycle processGO:00105641600.286
organelle localizationGO:00516401790.260
mitotic cell cycle processGO:19030471590.254
maintenance of locationGO:0051235890.231
mitotic sister chromatid segregationGO:0000070140.217
ras protein signal transductionGO:0007265770.215
spindle assemblyGO:0051225130.207
apoptotic signaling pathwayGO:00971903060.205
meiotic nuclear divisionGO:00071261150.203
regulation of protein localizationGO:00328802310.188
purine nucleotide metabolic processGO:00061633020.177
nuclear divisionGO:00002801580.175
regulation of anatomical structure sizeGO:00900661780.168
chromatin organizationGO:00063252060.163
dna repairGO:00062811070.163
cell divisionGO:00513011200.161
microtubule organizing center organizationGO:0031023280.155
regulation of cell divisionGO:0051302760.147
nucleoside phosphate catabolic processGO:19012922220.141
mitotic cell cycleGO:00002781950.140
regulation of cellular catabolic processGO:00313292420.137
regulation of mitosisGO:0007088290.136
regulation of cytoskeleton organizationGO:00514931220.130
dna replicationGO:0006260520.120
chromosome segregationGO:0007059480.120
dna endoreduplicationGO:004202340.118
establishment of organelle localizationGO:00516561220.114
male gamete generationGO:00482322850.111
cleavage furrow formationGO:003608920.111
regulation of mitotic cell cycle phase transitionGO:1901990730.109
rho protein signal transductionGO:0007266320.106
purine nucleoside catabolic processGO:00061522050.105
meiotic cell cycleGO:00513211220.101
centrosome organizationGO:0051297260.097
regulation of bindingGO:00510981110.097
cellular amino acid metabolic processGO:00065201030.096
organelle fissionGO:00482851700.096
endomembrane system organizationGO:00102561470.094
mitotic cytokinesisGO:000028140.091
dna recombinationGO:0006310920.091
cellularizationGO:000734910.090
nucleoside catabolic processGO:00091642060.087
actin cytoskeleton organizationGO:00300362200.085
positive regulation of cell cycleGO:0045787920.085
spindle localizationGO:0051653220.085
centrosome cycleGO:0007098230.084
establishment of spindle localizationGO:0051293190.080
membrane organizationGO:00610242450.080
regulation of apoptotic signaling pathwayGO:20012331970.077
regulation of cellular component sizeGO:00325351210.075
protein localization to organelleGO:00333651850.074
purine nucleoside triphosphate catabolic processGO:00091462030.073
cytokinesisGO:0000910170.073
germ cell developmentGO:00072811850.072
negative regulation of cell cycle phase transitionGO:1901988480.071
nucleoside triphosphate metabolic processGO:00091412300.068
proteolysis involved in cellular protein catabolic processGO:00516031470.067
regulation of cellular amino acid metabolic processGO:000652150.066
meiosis iGO:0007127600.066
negative regulation of phosphorus metabolic processGO:00105631840.066
Mouse
purine ribonucleoside catabolic processGO:00461302050.065
protein catabolic processGO:00301632210.065
macromolecule catabolic processGO:00090572810.064
metaphase plate congressionGO:005131020.064
regulation of cell cycle phase transitionGO:1901987770.063
nucleobase containing small molecule metabolic processGO:00550863520.062
cellular response to dna damage stimulusGO:00069742070.061
cellular component assembly involved in morphogenesisGO:00109271390.061
positive regulation of cellular catabolic processGO:00313311480.061
response to radiationGO:00093141650.060
ribonucleoside catabolic processGO:00424542060.060
purine containing compound catabolic processGO:00725232130.060
nucleoside triphosphate catabolic processGO:00091432050.060
developmental maturationGO:00217001930.059
organic cyclic compound catabolic processGO:19013612950.059
positive regulation of cell cycle processGO:0090068610.059
negative regulation of cell cycleGO:00457861230.059
small gtpase mediated signal transductionGO:0007264970.058
reactive oxygen species metabolic processGO:0072593840.058
spindle organizationGO:0007051280.057
cellular amine metabolic processGO:0044106440.057
purine ribonucleotide catabolic processGO:00091542080.056
microtubule nucleationGO:000702020.054
purine ribonucleotide metabolic processGO:00091502900.054
regulation of protein serine threonine kinase activityGO:00719001570.054
actin polymerization or depolymerizationGO:0008154540.054
establishment or maintenance of cell polarityGO:0007163860.054
actin filament organizationGO:00070151130.054
ribonucleoside metabolic processGO:00091192450.053
purine nucleoside metabolic processGO:00422782410.052
positive regulation of organelle organizationGO:00106381280.052
regulation of protein kinase activityGO:00458592320.052
posttranscriptional regulation of gene expressionGO:00106081550.051
cilium morphogenesisGO:00602711020.051
maintenance of location in cellGO:0051651240.051
female gamete generationGO:0007292740.050
dna biosynthetic processGO:0071897220.050
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.050
protein polymerizationGO:0051258570.050
establishment of spindle orientationGO:0051294150.049
purine ribonucleoside metabolic processGO:00461282410.049
negative regulation of cell sizeGO:004579230.048
negative regulation of cellular component organizationGO:00511291940.048
covalent chromatin modificationGO:00165691630.047
cellular protein catabolic processGO:00442571550.047
chromatin modificationGO:00165681870.047
meiotic cell cycle processGO:1903046770.046
oogenesisGO:0048477560.046
cell fate commitmentGO:00451652100.046
forebrain developmentGO:00309003020.046
b cell activationGO:00421131610.046
positive regulation of protein kinase activityGO:00458601440.045
positive regulation of cell developmentGO:00107202370.044
regulation of mitotic cell cycleGO:00073461260.043
negative regulation of organelle organizationGO:0010639900.043
sister chromatid segregationGO:0000819200.042
spermatogenesisGO:00072832840.042
positive regulation of proteolysisGO:0045862850.042
multicellular organism growthGO:00352641610.041
regulation of cell motilityGO:20001452360.041
protein modification by small protein conjugation or removalGO:00706472070.040
nucleotide catabolic processGO:00091662170.040
purine nucleotide catabolic processGO:00061952110.040
centrosome duplicationGO:0051298160.040
centrosome separationGO:005129940.039
cellular ketone metabolic processGO:0042180840.039
ribose phosphate metabolic processGO:00196932910.039
regulation of cellular amine metabolic processGO:0033238200.038
stem cell proliferationGO:00720891170.038
female meiosis chromosome segregationGO:001632110.038
dna packagingGO:0006323300.038
organonitrogen compound catabolic processGO:19015652640.038
purine containing compound metabolic processGO:00725213110.038
regulation of actin filament lengthGO:0030832450.036
ribonucleotide metabolic processGO:00092592910.036
double strand break repairGO:0006302480.036
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
protein depolymerizationGO:0051261340.036
leukocyte differentiationGO:00025213420.036
positive regulation of mitotic metaphase anaphase transitionGO:004584220.036
purine ribonucleoside triphosphate metabolic processGO:00092052200.035
nucleoside phosphate metabolic processGO:00067533380.035
glycosyl compound metabolic processGO:19016572460.035
cellular response to abiotic stimulusGO:0071214560.035
oocyte differentiationGO:0009994350.035
organophosphate catabolic processGO:00464342320.035
amine metabolic processGO:0009308450.034
carbohydrate derivative catabolic processGO:19011362310.034
neural precursor cell proliferationGO:00613511210.033
histone modificationGO:00165701590.033
g0 to g1 transitionGO:004502330.033
negative regulation of cell proliferationGO:00082852960.033
cellular protein complex assemblyGO:00436231160.033
intrinsic apoptotic signaling pathwayGO:00971931320.032
regulation of mitotic spindle organizationGO:006023620.032
apical constrictionGO:000338340.032
meiotic dna repair synthesisGO:000071140.032
actomyosin structure organizationGO:0031032560.032
cation transportGO:00068123990.032
cytokinetic processGO:003250620.031
spindle assembly involved in female meiosisGO:000705630.031
negative regulation of cellular protein metabolic processGO:00322692470.031
membrane disassemblyGO:003039710.031
t cell proliferationGO:00420981200.031
mapk cascadeGO:00001652810.031
nucleotide metabolic processGO:00091173320.031
regulation of kinase activityGO:00435492490.031
regulation of actin filament based processGO:0032970990.030
regulation of proteolysisGO:00301621640.030
heterocycle catabolic processGO:00467002800.030
rhythmic processGO:00485111740.030
regulation of stem cell proliferationGO:0072091780.030
positive regulation of cellular amine metabolic processGO:003324050.030
peptidyl serine modificationGO:0018209830.030
immune effector processGO:00022523210.030
purine ribonucleoside monophosphate catabolic processGO:0009169570.030
regulation of cell migrationGO:00303342190.030
ubiquitin dependent protein catabolic processGO:00065111290.030
spindle assembly involved in meiosisGO:009030640.030
lateral inhibitionGO:004633110.029
meiotic chromosome segregationGO:0045132190.029
t cell activationGO:00421102890.029
glycosyl compound catabolic processGO:19016582060.029
chromosome condensationGO:0030261100.029
regulation of actin polymerization or depolymerizationGO:0008064450.029
reciprocal meiotic recombinationGO:0007131160.028
endocytosisGO:00068971680.028
development of primary sexual characteristicsGO:00451371430.028
establishment or maintenance of cytoskeleton polarityGO:003095220.028
positive regulation of hydrolase activityGO:00513451480.028
divalent inorganic cation transportGO:00725111780.028
cell cycle checkpointGO:0000075470.028
response to organonitrogen compoundGO:00102432460.028
modification dependent protein catabolic processGO:00199411330.027
cellular nitrogen compound catabolic processGO:00442702800.027
positive regulation of cell deathGO:00109422240.027
regulation of cellular response to stressGO:00801351590.027
peptidyl amino acid modificationGO:00181933360.027
double strand break repair via homologous recombinationGO:0000724210.027
gonad developmentGO:00084061410.027
actin filament polymerizationGO:0030041440.027
cell agingGO:0007569350.027
germinal center formationGO:0002467160.026
modification dependent macromolecule catabolic processGO:00436321330.026
eye photoreceptor cell differentiationGO:0001754410.026
positive regulation of nervous system developmentGO:00519622210.026
positive regulation of programmed cell deathGO:00430682180.026
positive regulation of protein modification processGO:00314012990.025
purine nucleoside monophosphate catabolic processGO:0009128580.025
purine ribonucleoside monophosphate metabolic processGO:0009167800.025
establishment of meiotic spindle orientationGO:005129610.025
meiosis iiGO:000713570.025
negative regulation of phosphorylationGO:00423261660.025
ribonucleoside triphosphate metabolic processGO:00091992200.024
negative regulation of mitotic cell cycleGO:0045930580.024
placenta developmentGO:00018901400.024
regulation of nuclear cell cycle dna replicationGO:003326220.024
cellular response to radiationGO:0071478280.024
regulation of cellular ketone metabolic processGO:0010565660.024
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.024
negative regulation of protein modification processGO:00314001630.024
regulation of cytokine productionGO:00018172660.024
Mouse
wnt signaling pathwayGO:00160551880.024
cell type specific apoptotic processGO:00972852680.024
cellular response to cytokine stimulusGO:00713451890.024
cytokine productionGO:00018163190.023
Mouse
positive regulation of transferase activityGO:00513471670.023
regulation of nuclear divisionGO:0051783560.023
lymphocyte apoptotic processGO:0070227540.023
regulation of protein bindingGO:0043393600.023
ribonucleoside triphosphate catabolic processGO:00092031990.023
stem cell developmentGO:00488642190.023
regulation of exit from mitosisGO:000709610.023
regulation of reactive oxygen species metabolic processGO:2000377400.023
positive regulation of cellular protein catabolic processGO:1903364340.022
negative regulation of molecular functionGO:00440922580.022
response to light stimulusGO:00094161350.022
regulation of nucleoside metabolic processGO:00091181300.022
mitotic spindle organizationGO:0007052100.022
homeostasis of number of cellsGO:00488722100.022
purine nucleoside monophosphate metabolic processGO:0009126810.022
stem cell maintenanceGO:00198271300.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
protein processingGO:00164851630.022
aromatic compound catabolic processGO:00194392860.021
astral microtubule organizationGO:003095330.021
regulation of protein stabilityGO:0031647520.021
proteasomal protein catabolic processGO:0010498980.021
dna conformation changeGO:0071103370.021
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.021
positive regulation of apoptotic processGO:00430652170.021
extracellular structure organizationGO:00430621480.021
negative regulation of protein metabolic processGO:00512482820.021
cell cycle g2 m phase transitionGO:0044839200.020
regulation of cysteine type endopeptidase activityGO:2000116650.020
cellular homeostasisGO:00197252400.020
meiotic cytokinesisGO:003320650.020
multicellular organismal homeostasisGO:00488711640.020
response to cell cycle checkpoint signalingGO:007239610.020
positive regulation of protein phosphorylationGO:00019342420.020
positive regulation of mitotic cell cycleGO:0045931410.020
mitotic sister chromatid separationGO:005130690.020
muscle tissue developmentGO:00605373080.020
regulation of purine nucleotide catabolic processGO:00331211220.020
negative regulation of cytoskeleton organizationGO:0051494360.020
dna integrity checkpointGO:0031570280.020
regulation of leukocyte apoptotic processGO:2000106560.020
nucleoside metabolic processGO:00091162460.020
negative regulation of cytokine productionGO:0001818840.020
positive regulation of cell divisionGO:0051781310.019
regulation of nucleotide metabolic processGO:00061401690.019
regulation of t cell activationGO:00508631700.019
protein ubiquitinationGO:00165671710.019
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.019
positive regulation of protein catabolic processGO:0045732600.019
positive regulation of nucleotide metabolic processGO:00459811140.019
negative regulation of cellular amino acid metabolic processGO:004576300.019
positive regulation of purine nucleotide metabolic processGO:19005441140.019
regulation of protein catabolic processGO:00421761080.019
regulation of neuron differentiationGO:00456642810.018
stem cell differentiationGO:00488632680.018
cell adhesionGO:00071553290.018
negative regulation of nervous system developmentGO:00519611560.018
regulation of establishment of protein localizationGO:00702011810.018
regulation of mitotic sister chromatid segregationGO:0033047120.018
regulation of cell sizeGO:0008361720.018
fertilizationGO:00095661270.018
regulation of actin filament polymerizationGO:0030833380.018
epithelial tube morphogenesisGO:00605623030.018
establishment of mitotic spindle localizationGO:0040001120.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
protein secretionGO:00093061110.017
g1 s transition of mitotic cell cycleGO:0000082570.017
ribonucleotide catabolic processGO:00092612080.017
blood vessel morphogenesisGO:00485142850.017
b cell apoptotic processGO:0001783190.017
meiotic spindle organizationGO:000021290.017
macromolecule methylationGO:00434141200.017
guanosine containing compound catabolic processGO:19010691440.017
epithelial cell developmentGO:00020641590.017
digestive tract morphogenesisGO:00485461470.017
protein targetingGO:00066051430.017
regulation of cell projection organizationGO:00313442060.017
leukocyte apoptotic processGO:0071887710.016
cellular macromolecule catabolic processGO:00442652060.016
ossificationGO:00015032160.016
divalent metal ion transportGO:00708381720.016
regulation of neural precursor cell proliferationGO:2000177700.016
regulation of endopeptidase activityGO:0052548890.016
leukocyte migrationGO:00509001240.016
negative regulation of cellular amine metabolic processGO:003323910.016
chromosome movement towards spindle poleGO:005130530.016
lens fiber cell apoptotic processGO:199008640.016
hindbrain tangential cell migrationGO:002193420.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.015
negative regulation of bindingGO:0051100390.015
positive regulation of neuron differentiationGO:00456661410.015
neuron apoptotic processGO:00514021420.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
regulation of peptidase activityGO:0052547960.015
digestive system developmentGO:00551232000.015
positive regulation of chromosome segregationGO:005198440.015
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.015
establishment of protein localization to organelleGO:00725941180.015
calcium ion transportGO:00068161590.015
protein dna complex subunit organizationGO:0071824280.015
negative regulation of cell agingGO:009034450.015
striated muscle tissue developmentGO:00147062930.015
atp metabolic processGO:0046034750.015
recombinational repairGO:0000725210.015
muscle cell differentiationGO:00426922610.015
response to organic cyclic compoundGO:00140701980.015
skeletal system morphogenesisGO:00487052030.015
protein modification by small protein conjugationGO:00324461870.014
mitotic sister chromatid cohesionGO:000706410.014
regulation of proteasomal protein catabolic processGO:0061136460.014
cell maturationGO:00484691270.014
nucleus organizationGO:0006997450.014
negative regulation of lymphocyte proliferationGO:0050672450.014
negative regulation of mitotic cell cycle phase transitionGO:1901991450.014
regulation of neuroblast proliferationGO:1902692270.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
gtp catabolic processGO:00061841430.014
negative regulation of intracellular signal transductionGO:19025321670.014
regulation of synaptic plasticityGO:0048167870.014
organonitrogen compound biosynthetic processGO:19015661920.014
metaphase anaphase transition of mitotic cell cycleGO:000709190.014
stress activated protein kinase signaling cascadeGO:0031098810.014
positive regulation of gtpase activityGO:0043547850.014
dendrite developmentGO:00163581150.014
positive regulation of chromosome organizationGO:2001252330.014
regulation of stress activated mapk cascadeGO:0032872690.014
localization within membraneGO:005166840.014
digestive tract developmentGO:00485651900.014
regulation of purine nucleotide metabolic processGO:19005421690.014
sensory perceptionGO:00076002450.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.013
signal transduction by p53 class mediatorGO:0072331510.013
protein importGO:00170381010.013
negative regulation of immune system processGO:00026832090.013
interleukin 6 productionGO:0032635580.013
negative regulation of leukocyte proliferationGO:0070664460.013
regulation of response to woundingGO:19030341890.013
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.013
circulatory system processGO:00030131970.013
organic hydroxy compound metabolic processGO:19016152030.013
nucleoside monophosphate metabolic processGO:0009123850.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
regulation of leukocyte differentiationGO:19021051590.013
regulation of nucleotide catabolic processGO:00308111220.013
regulation of cellular component biogenesisGO:00440871810.013
positive regulation of wnt signaling pathwayGO:0030177450.013
humoral immune responseGO:0006959570.013
positive regulation of mitotic sister chromatid separationGO:190197020.013
cytoplasmic transportGO:00164822340.013
regulation of actin cytoskeleton organizationGO:0032956840.013
positive regulation of kinase activityGO:00336741550.013
regulation of chromatin organizationGO:1902275570.012
ribonucleoside monophosphate catabolic processGO:0009158570.012
regulation of lymphocyte proliferationGO:00506701170.012
mitotic nuclear divisionGO:0007067480.012
gliogenesisGO:00420631410.012
peptidyl serine phosphorylationGO:0018105740.012
microtubule anchoringGO:003445390.012
single fertilizationGO:0007338820.012
leukocyte proliferationGO:00706611720.012
sensory organ morphogenesisGO:00905962420.012
lymphocyte proliferationGO:00466511640.012
regulation of mitotic sister chromatid separationGO:0010965120.012
cellular response to inorganic substanceGO:0071241370.012
erythrocyte differentiationGO:0030218880.012
protein import into nucleusGO:0006606950.012
regulation of sequence specific dna binding transcription factor activityGO:00510901060.012
positive regulation of nuclear divisionGO:0051785270.012
cilium assemblyGO:0042384810.012
meiotic chromosome separationGO:005130750.012
myosin filament assemblyGO:003103420.012
microtubule based movementGO:0007018840.012
regulation of ras gtpase activityGO:0032318880.012
response to molecule of bacterial originGO:00022371430.012
regulation of dna bindingGO:0051101390.012
regulation of secretionGO:00510462740.012
transmembrane transportGO:00550854120.012
mitotic cell cycle checkpointGO:0007093310.012
negative regulation of protein transportGO:0051224460.012
locomotory behaviorGO:00076261950.011
cytokine metabolic processGO:0042107710.011
positive regulation of exit from mitosisGO:003153610.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
regulation of wnt signaling pathwayGO:00301111230.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
negative regulation of phosphate metabolic processGO:00459361840.011
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.011
regulation of gtp catabolic processGO:00331241130.011
cellular response to biotic stimulusGO:0071216920.011
er nucleus signaling pathwayGO:0006984270.011
anatomical structure homeostasisGO:00602491450.011
plasma membrane organizationGO:0007009900.011
pallium developmentGO:00215431200.011
response to inorganic substanceGO:0010035960.011
cellular response to calcium ionGO:0071277140.011
cell cycle g1 s phase transitionGO:0044843570.011
protein localization to chromatinGO:007116830.011
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.011
wound healingGO:00420601570.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
regulation of rho protein signal transductionGO:0035023710.011
oocyte developmentGO:0048599330.011
response to decreased oxygen levelsGO:0036293590.010
cellular response to organonitrogen compoundGO:00714171450.010
peptidyl lysine modificationGO:0018205770.010
sister chromatid cohesionGO:0007062120.010
intestinal epithelial structure maintenanceGO:006072940.010
cell cycle arrestGO:0007050370.010
nuclear dna replicationGO:003326030.010
atp catabolic processGO:0006200550.010
intracellular protein transportGO:00068862040.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
regulation of t cell proliferationGO:0042129920.010
protein oligomerizationGO:0051259670.010
lipid localizationGO:00108761260.010
negative regulation of proteolysisGO:0045861740.010

Iqgap3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:008001500.016
congenital nervous system abnormalityDOID:249000.016
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
cancerDOID:16200.015
thoracic cancerDOID:509300.015
intestinal cancerDOID:1015500.013
gastrointestinal system cancerDOID:311900.013