Mus musculus

303 known processes

Tlr2

toll-like receptor 2

(Aliases: Ly105)

Tlr2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of molecule of bacterial originGO:003249020.994
cellular response to molecule of bacterial originGO:0071219830.992
response to molecule of bacterial originGO:00022371430.990
cellular response to lipidGO:00713961450.989
Mouse
interleukin 18 mediated signaling pathwayGO:003565520.977
cellular response to lipopolysaccharideGO:0071222770.975
Mouse
positive regulation of reactive oxygen species metabolic processGO:2000379110.967
positive regulation of interleukin 18 productionGO:003274120.966
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.962
reactive oxygen species metabolic processGO:0072593840.953
cellular response to interleukin 18GO:007135130.952
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.940
eosinophil degranulationGO:004330810.940
lipopolysaccharide mediated signaling pathwayGO:0031663250.937
Mouse
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.936
positive regulation of leukocyte proliferationGO:0070665730.934
Mouse
response to lipopolysaccharideGO:00324961280.932
Mouse
regulation of cytokine productionGO:00018172660.912
response to molecule of fungal originGO:000223840.902
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.902
Mouse
negative regulation of macrophage apoptotic processGO:200011030.896
lymphocyte activation involved in immune responseGO:0002285930.895
Mouse
immune complex clearance by monocytes and macrophagesGO:000243620.882
innate immune response activating cell surface receptor signaling pathwayGO:000222040.867
reactive nitrogen species metabolic processGO:200105700.863
defense response to other organismGO:00985421970.857
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043420.837
Mouse
cytokine productionGO:00018163190.829
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.827
Mouse
positive regulation of t cell receptor signaling pathwayGO:005086240.824
cellular response to biotic stimulusGO:0071216920.799
positive regulation of defense responseGO:00313491240.795
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.785
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.783
positive regulation of immunological synapse formationGO:200052210.777
immune response activating signal transductionGO:00027571160.762
pattern recognition receptor signaling pathwayGO:0002221470.760
modulation by symbiont of defense related host nitric oxide productionGO:005216310.745
positive regulation of interferon beta biosynthetic processGO:004535930.740
Mouse
positive regulation of cell activationGO:00508671580.735
Mouse
regulation of innate immune responseGO:0045088910.724
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.723
Mouse
t cell extravasationGO:007268340.723
cellular response to bacterial lipoproteinGO:007122030.715
leukocyte mediated immunityGO:00024431740.714
modulation by symbiont of host immune responseGO:005255310.713
immune response regulating cell surface receptor signaling pathwayGO:0002768800.712
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.710
cytokine mediated signaling pathwayGO:00192211150.701
eosinophil activation involved in immune responseGO:000227810.699
nitric oxide biosynthetic processGO:0006809250.694
cellular response to cytokine stimulusGO:00713451890.691
positive regulation of cytokine productionGO:00018191740.663
regulation of acute inflammatory responseGO:0002673270.655
innate immune responseGO:00450871570.654
regulation of inflammatory responseGO:00507271470.649
Mouse
response to bacterial lipoproteinGO:003249340.645
regulation of cellular amine metabolic processGO:0033238200.643
cytokine production involved in immune responseGO:0002367340.637
microglial cell activationGO:000177430.631
regulation of cytokine production involved in immune responseGO:0002718260.628
immune effector processGO:00022523210.620
leukocyte activation involved in immune responseGO:00023661260.607
Mouse
interferon beta biosynthetic processGO:004535040.602
Mouse
regulation of reactive oxygen species metabolic processGO:2000377400.601
response to bacterial lipopeptideGO:007033930.600
positive regulation of chemokine biosynthetic processGO:004508060.599
response to hostGO:007513630.588
response to host defensesGO:005220030.587
positive regulation by symbiont of host defense responseGO:005250910.577
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.576
Mouse
regulation of defense responseGO:00313472330.575
interleukin 8 productionGO:003263740.569
cellular response to bacterial lipopeptideGO:007122130.567
intracellular receptor signaling pathwayGO:0030522740.556
Mouse
immune response regulating signaling pathwayGO:00027641250.553
antimicrobial peptide productionGO:000277520.550
cell surface pattern recognition receptor signaling pathwayGO:000275220.540
positive regulation of chemokine productionGO:0032722220.534
regulation of secretion by cellGO:19035302490.529
mature dendritic cell differentiationGO:009702930.516
regulation of cellular amino acid metabolic processGO:000652150.516
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005230210.508
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.502
regulation of inflammatory response to antigenic stimulusGO:0002861210.500
regulation of interleukin 23 productionGO:003266720.494
Mouse
nitric oxide production involved in inflammatory responseGO:000253720.492
Mouse
cytoplasmic transportGO:00164822340.490
regulation of lymphocyte proliferationGO:00506701170.485
Mouse
negative regulation of cytokine productionGO:0001818840.481
microglial cell activation involved in immune responseGO:000228210.480
action potentialGO:0001508780.475
induction by organism of defense response of other organism involved in symbiotic interactionGO:005225110.467
innate immune response activating signal transductionGO:0002758500.467
regulation of growth of symbiont in hostGO:0044126190.463
antibiotic transportGO:004289110.459
vascular endothelial growth factor productionGO:0010573130.459
regulation of macrophage cytokine productionGO:001093580.457
apoptotic signaling pathwayGO:00971903060.454
regulation of homeostatic processGO:00328441820.443
regulation of reactive oxygen species biosynthetic processGO:190342620.426
myeloid leukocyte mediated immunityGO:0002444420.424
myeloid leukocyte migrationGO:0097529570.423
superoxide metabolic processGO:0006801270.422
inflammatory responseGO:00069542440.421
Mouse
response to interleukin 12GO:007067120.415
helper t cell chemotaxisGO:003570410.413
g protein coupled receptor signaling pathwayGO:00071862430.409
chemokine metabolic processGO:0050755100.409
immunoglobulin mediated immune responseGO:0016064690.409
production of molecular mediator involved in inflammatory responseGO:0002532210.408
Mouse
activation of innate immune responseGO:0002218560.402
i kappab kinase nf kappab signalingGO:0007249850.401
Mouse
positive regulation of apoptotic cell clearanceGO:200042730.400
t cell activationGO:00421102890.397
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.388
Mouse
ripoptosome assembly involved in necroptotic processGO:190102660.382
induction by symbiont of host immune responseGO:005255910.381
positive regulation of erk1 and erk2 cascadeGO:0070374470.380
Mouse
cation homeostasisGO:00550802120.375
cellular chemical homeostasisGO:00550822150.375
chemokine mediated signaling pathwayGO:0070098170.373
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005234510.372
interleukin 17 productionGO:0032620110.372
regulation of angiogenesisGO:0045765810.368
regulation of protein transportGO:00512231630.366
regulation of tumor necrosis factor productionGO:0032680490.364
positive regulation of t cell extravasationGO:200040920.363
positive regulation of innate immune responseGO:0045089800.363
skeletal system developmentGO:00015013560.363
positive regulation of monocyte chemotaxisGO:009002620.360
regulation of sequence specific dna binding transcription factor activityGO:00510901060.359
negative regulation of eosinophil degranulationGO:004331010.358
leukocyte migrationGO:00509001240.353
adaptive immune responseGO:00022501550.351
positive regulation of macrophage cytokine productionGO:006090770.350
regulation of tumor necrosis factor biosynthetic processGO:0042534100.348
cellular response to growth factor stimulusGO:00713631970.348
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.347
modulation by organism of defense response of other organism involved in symbiotic interactionGO:005225510.346
eosinophil activationGO:004330710.346
intestinal cholesterol absorptionGO:003029950.345
positive regulation of interferon alpha productionGO:003272740.344
Mouse
chemokine productionGO:0032602340.342
positive regulation of hemostasisGO:1900048100.341
Mouse
positive regulation of cellular amine metabolic processGO:003324050.335
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.334
Mouse
regulation of cell motilityGO:20001452360.334
positive regulation by symbiont of host immune responseGO:005255610.330
response to defense related host nitric oxide productionGO:005256520.325
inflammatory response to woundingGO:009059440.325
positive regulation of t cell costimulationGO:200052520.323
negative regulation of multi organism processGO:0043901680.321
regulation of cellular response to stressGO:00801351590.321
Mouse
positive regulation of hypersensitivityGO:000288570.319
maintenance of locationGO:0051235890.317
growth involved in symbiotic interactionGO:0044110230.316
granulocyte migrationGO:0097530430.316
interleukin 23 productionGO:003262720.315
Mouse
interspecies interaction between organismsGO:0044419830.307
positive regulation of leukocyte mediated immunityGO:0002705700.303
cellular ion homeostasisGO:00068731650.302
regulation of dendritic cell chemotaxisGO:200050810.302
positive regulation of apoptotic signaling pathwayGO:2001235950.301
positive regulation of immune effector processGO:00026991070.300
positive regulation of tumor necrosis factor biosynthetic processGO:004253580.293
regulation of cellular ketone metabolic processGO:0010565660.290
immune complex clearanceGO:000243420.289
cellular metal ion homeostasisGO:00068751510.288
membrane organizationGO:00610242450.285
purine ribonucleoside triphosphate metabolic processGO:00092052200.284
purine containing compound metabolic processGO:00725213110.277
purine ribonucleoside metabolic processGO:00461282410.275
positive regulation of t cell proliferationGO:0042102520.275
response to defenses of other organism involved in symbiotic interactionGO:005217330.274
metal ion homeostasisGO:00550651890.272
regulation of leukocyte proliferationGO:00706631210.271
Mouse
regulation of secretionGO:00510462740.269
regulation of vitamin d biosynthetic processGO:006055610.265
positive regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042620.262
Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.262
positive regulation of cytokine biosynthetic processGO:0042108400.261
cellular amine metabolic processGO:0044106440.261
regulation of apoptotic signaling pathwayGO:20012331970.257
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.257
symbiosis encompassing mutualism through parasitismGO:0044403830.256
positive regulation of nf kappab transcription factor activityGO:0051092300.255
positive regulation of response to woundingGO:1903036660.254
Mouse
regulation of ion homeostasisGO:2000021640.253
regulation of monocyte extravasationGO:200043720.251
toll like receptor signaling pathwayGO:0002224380.250
regulation of leukocyte mediated immunityGO:00027031040.246
defense response to bacteriumGO:00427421190.246
positive regulation of kinase activityGO:00336741550.246
Mouse
negative regulation of immune system processGO:00026832090.246
myeloid leukocyte activationGO:0002274830.245
leukocyte differentiationGO:00025213420.244
cellular amino acid metabolic processGO:00065201030.244
nucleoside metabolic processGO:00091162460.242
positive regulation of lymphocyte proliferationGO:0050671700.242
Mouse
regulation of cytokine biosynthetic processGO:0042035590.241
positive regulation of cytosolic calcium ion concentrationGO:0007204650.239
activation of immune responseGO:00022531380.238
regulation of endocytosisGO:0030100690.237
regulation of hypersensitivityGO:0002883100.234
cellular ketone metabolic processGO:0042180840.232
positive regulation of coagulationGO:0050820130.232
Mouse
cytosolic calcium ion transportGO:0060401480.231
regulation of hydrolase activityGO:00513362460.231
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.230
Mouse
mapk cascadeGO:00001652810.228
Mouse
regulation of interleukin 18 productionGO:003266130.226
defense response to gram positive bacteriumGO:0050830500.226
positive regulation of protein modification processGO:00314012990.223
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.221
neutrophil chemotaxisGO:0030593360.221
myeloid cell differentiationGO:00300992330.219
tumor necrosis factor superfamily cytokine productionGO:0071706510.218
regulation of ion transportGO:00432692150.216
negative regulation of innate immune responseGO:0045824170.215
lymphocyte migrationGO:0072676260.215
neutrophil apoptotic processGO:000178130.214
b cell proliferationGO:0042100530.213
Mouse
regulation of response to woundingGO:19030341890.212
Mouse
response to organic cyclic compoundGO:00140701980.210
negative regulation of interleukin 6 productionGO:0032715170.209
Mouse
positive regulation of programmed cell deathGO:00430682180.209
positive regulation of mapk cascadeGO:00434101700.209
Mouse
modulation by organism of immune response of other organism involved in symbiotic interactionGO:005255210.208
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.205
carbohydrate metabolic processGO:00059752300.203
nucleobase containing small molecule metabolic processGO:00550863520.203
organophosphate biosynthetic processGO:00904071220.200
acute inflammatory responseGO:0002526410.196
regulation of myeloid leukocyte mediated immunityGO:0002886250.194
positive regulation of b cell proliferationGO:0030890240.194
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.191
Mouse
antibacterial peptide productionGO:000277820.191
negative regulation of growthGO:0045926990.190
cellular response to acid chemicalGO:0071229680.187
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.186
Mouse
response to host immune responseGO:005257230.185
b cell activation involved in immune responseGO:0002312500.184
Mouse
regulation of antigen receptor mediated signaling pathwayGO:0050854290.184
positive regulation of phagocytosisGO:0050766260.183
eosinophil mediated immunityGO:000244710.183
granulocyte chemotaxisGO:0071621390.181
positive regulation of cellular amino acid metabolic processGO:004576430.181
regulation of interleukin 6 productionGO:0032675550.181
detection of lipopolysaccharideGO:003249710.180
regulation of phagocytosisGO:0050764330.179
nucleoside phosphate biosynthetic processGO:1901293790.177
regulation of nitric oxide biosynthetic processGO:0045428180.176
cellular response to lipoteichoic acidGO:007122360.172
regulation of t cell extravasationGO:200040730.171
tumor necrosis factor productionGO:0032640500.171
regulation of vesicle mediated transportGO:00606271390.171
regulation of circadian rhythmGO:0042752580.169
positive regulation of adaptive immune responseGO:0002821610.167
regulation of mhc class ii biosynthetic processGO:004534670.165
Mouse
positive regulation of acute inflammatory response to antigenic stimulusGO:000286670.164
cellular response to tumor necrosis factorGO:0071356210.164
cell activation involved in immune responseGO:00022631260.164
Mouse
response to fatty acidGO:007054280.163
regulation of removal of superoxide radicalsGO:200012140.161
response to immune response of other organism involved in symbiotic interactionGO:005256430.161
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.161
regulation of protein localizationGO:00328802310.161
positive regulation of cell deathGO:00109422240.161
positive regulation of protein secretionGO:0050714520.160
necroptotic signaling pathwayGO:009752730.158
regulation of b cell activationGO:0050864810.156
Mouse
regulation of t cell costimulationGO:200052320.156
fat soluble vitamin biosynthetic processGO:004236240.156
positive regulation of cytokine production involved in immune responseGO:0002720190.154
positive regulation of cell developmentGO:00107202370.154
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.153
b cell mediated immunityGO:0019724710.153
regulation of protein secretionGO:0050708820.152
cellular calcium ion homeostasisGO:00068741190.152
regulation of vascular endothelial growth factor productionGO:0010574130.151
cell substrate adhesionGO:00315891300.150
regulation of membrane potentialGO:00423911920.149
positive regulation of behaviorGO:0048520400.149
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.147
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.147
ribonucleoside triphosphate metabolic processGO:00091992200.147
positive regulation of monocyte extravasationGO:200043910.144
interleukin 18 productionGO:003262140.144
production of molecular mediator of immune responseGO:00024401030.144
cellular lipid metabolic processGO:00442553230.144
positive regulation of antimicrobial peptide productionGO:000222510.143
positive regulation of dendritic cell chemotaxisGO:200051010.143
positive regulation of interleukin 6 biosynthetic processGO:004541060.143
Mouse
modification of morphology or physiology of other organismGO:0035821180.142
positive regulation of acute inflammatory responseGO:0002675160.142
lipid localizationGO:00108761260.141
positive regulation of interleukin 17 productionGO:003274030.140
positive regulation of b cell mediated immunityGO:0002714260.140
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.139
negative regulation of endopeptidase activityGO:0010951440.139
divalent inorganic cation homeostasisGO:00725071380.138
response to interleukin 1GO:0070555110.137
sequestering of metal ionGO:0051238190.137
sequestering of calcium ionGO:0051208180.137
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.137
Mouse
regulation of defense response to fungusGO:190015010.135
purine nucleotide biosynthetic processGO:0006164650.135
anion transportGO:00068201770.135
negative regulation of cellular protein metabolic processGO:00322692470.134
morphogenesis of a branching epitheliumGO:00611381930.133
ribose phosphate metabolic processGO:00196932910.132
response to inorganic substanceGO:0010035960.132
cellular response to inorganic substanceGO:0071241370.131
detection of biotic stimulusGO:0009595100.131
response to activityGO:0014823130.131
cytosolic calcium ion homeostasisGO:0051480700.130
protein localization to nucleusGO:00345041210.130
neuronal action potentialGO:0019228540.130
leukocyte proliferationGO:00706611720.130
Mouse
muscle tissue developmentGO:00605373080.129
regulation of myeloid cell differentiationGO:0045637960.129
negative regulation of leukocyte proliferationGO:0070664460.128
regulation of cytoplasmic transportGO:19036491120.127
regulation of production of molecular mediator of immune responseGO:0002700650.127
positive regulation by organism of immune response of other organism involved in symbiotic interactionGO:005255510.126
negative regulation of defense responseGO:0031348770.126
cellular response to organonitrogen compoundGO:00714171450.126
signal transduction in absence of ligandGO:0038034550.125
leukocyte apoptotic processGO:0071887710.125
positive regulation of macrophage chemotaxisGO:001075950.125
interferon beta productionGO:0032608160.124
chemotaxisGO:00069352470.124
myeloid leukocyte cytokine productionGO:0061082120.124
negative regulation of phosphate metabolic processGO:00459361840.124
Mouse
cation transportGO:00068123990.123
nucleoside phosphate metabolic processGO:00067533380.123
response to low density lipoprotein particleGO:005509820.122
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817160.122
alpha beta t cell proliferationGO:0046633210.122
myeloid cell activation involved in immune responseGO:0002275340.122
regulation of muscle tissue developmentGO:1901861970.121
response to inactivityGO:001485440.121
erk1 and erk2 cascadeGO:0070371770.121
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.121
regulation of leukocyte differentiationGO:19021051590.121
response to organonitrogen compoundGO:00102432460.120
bone trabecula morphogenesisGO:0061430120.120
monocarboxylic acid metabolic processGO:00327871910.119
interleukin 12 secretionGO:007261030.119
response to acid chemicalGO:00011011110.119
sensory perceptionGO:00076002450.119
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.119
intrinsic apoptotic signaling pathwayGO:00971931320.118
lipid biosynthetic processGO:00086101790.118
interleukin 6 biosynthetic processGO:0042226120.118
Mouse
cd8 positive alpha beta t cell extravasationGO:003569730.117
positive regulation of reactive oxygen species biosynthetic processGO:190342820.116
nitric oxide metabolic processGO:0046209250.115
purine ribonucleoside biosynthetic processGO:0046129190.114
negative regulation of intracellular signal transductionGO:19025321670.113
Mouse
positive regulation of atp biosynthetic processGO:200117120.112
b cell proliferation involved in immune responseGO:000232250.112
Mouse
blood coagulationGO:0007596760.111
Mouse
purine nucleoside catabolic processGO:00061522050.110
purine nucleoside metabolic processGO:00422782410.110
negative regulation of protein metabolic processGO:00512482820.110
cell type specific apoptotic processGO:00972852680.109
inflammatory cell apoptotic processGO:0006925110.109
positive regulation of leukocyte differentiationGO:1902107860.108
cellular homeostasisGO:00197252400.108
response to steroid hormoneGO:0048545560.108
regulation of cell activationGO:00508652890.107
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.106
positive regulation of oligodendrocyte differentiationGO:004871490.106
positive regulation of interferon gamma productionGO:0032729390.105
Mouse
epithelial tube morphogenesisGO:00605623030.105
lipid storageGO:0019915360.105
regulation of interferon gamma productionGO:0032649570.105
Mouse
regulation of hemostasisGO:1900046280.105
Mouse
nucleotide biosynthetic processGO:0009165780.104
negative regulation of t cell activationGO:0050868650.104
morphogenesis of a branching structureGO:00017632030.104
nucleoside biosynthetic processGO:0009163210.103
organonitrogen compound catabolic processGO:19015652640.103
cellular response to prostaglandin stimulusGO:007137920.102
peptidyl serine modificationGO:0018209830.102
protein localization to organelleGO:00333651850.102
response to drugGO:0042493750.102
positive regulation of hematopoietic stem cell migrationGO:200047310.102
regulation of establishment of protein localizationGO:00702011810.101
lymphocyte mediated immunityGO:00024491390.100
macrophage cytokine productionGO:001093490.100
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.099
glycerolipid biosynthetic processGO:0045017500.099
multicellular organismal signalingGO:0035637910.099
response to sterolGO:003631440.099
negative regulation of blood vessel morphogenesisGO:2000181250.098
necroptotic processGO:0070266210.098
nucleoside monophosphate metabolic processGO:0009123850.097
regulation of oligodendrocyte differentiationGO:0048713230.097
myelinationGO:0042552740.097
regulated secretory pathwayGO:0045055320.096
positive regulation of intracellular transportGO:0032388700.096
response to tumor necrosis factorGO:0034612260.094
positive regulation of t helper 1 cell differentiationGO:004562740.094
peptidyl amino acid modificationGO:00181933360.093
lymphocyte proliferationGO:00466511640.093
Mouse
fatty acid metabolic processGO:00066311210.092
positive regulation of protein transportGO:0051222930.092
small gtpase mediated signal transductionGO:0007264970.092
negative regulation of homeostatic processGO:0032845710.091
toll like receptor 7 signaling pathwayGO:003415440.090
regulation of intracellular protein transportGO:0033157820.090
calcium ion homeostasisGO:00550741270.089
organonitrogen compound biosynthetic processGO:19015661920.088
regulation of nucleoside metabolic processGO:00091181300.088
cellular response to vitaminGO:007129520.088
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.087
positive regulation of secretionGO:00510471300.087
positive regulation of secretion by cellGO:19035321140.087
positive regulation of neuron apoptotic processGO:0043525250.087
homeostasis of number of cellsGO:00488722100.086
positive regulation of organelle organizationGO:00106381280.086
dendritic cell differentiationGO:0097028260.086
macromolecule catabolic processGO:00090572810.086
positive regulation of myeloid cell differentiationGO:0045639430.085
extrinsic apoptotic signaling pathwayGO:00971911260.084
acute inflammatory response to antigenic stimulusGO:0002438120.084
phospholipid metabolic processGO:0006644870.084
cellular response to interferon gammaGO:0071346250.083
regulation of interleukin 2 productionGO:0032663280.083
response to interferon gammaGO:0034341340.083
endocytosisGO:00068971680.083
regulation of alpha beta t cell activationGO:0046634530.082
cytokine metabolic processGO:0042107710.082
dephosphorylationGO:00163111290.081
positive regulation of nucleotide biosynthetic processGO:0030810260.081
regulation of acute inflammatory response to antigenic stimulusGO:0002864100.081
regulation of cell adhesionGO:00301551540.081
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.081
regulation of lymphocyte activationGO:00512492400.081
Mouse
epidermis developmentGO:00085441870.081
organic hydroxy compound biosynthetic processGO:1901617770.080
regulation of alpha beta t cell proliferationGO:0046640180.080
myeloid leukocyte differentiationGO:00025731190.079
inflammatory response to antigenic stimulusGO:0002437300.078
positive regulation of interleukin 6 productionGO:0032755370.078
protein catabolic processGO:00301632210.078
divalent metal ion transportGO:00708381720.078
branching involved in mammary gland duct morphogenesisGO:0060444270.077
negative regulation of molecular functionGO:00440922580.077
regulation of neutrophil chemotaxisGO:0090022140.077
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.077
positive regulation of production of molecular mediator of immune responseGO:0002702450.076
negative regulation of secretion by cellGO:1903531540.075
regulation of cell migrationGO:00303342190.075
positive regulation of activation of membrane attack complexGO:000197020.075
organic acid transportGO:00158491010.075
transmission of nerve impulseGO:0019226760.075
rho protein signal transductionGO:0007266320.075
digestionGO:0007586400.074
Mouse
negative regulation of hydrolase activityGO:0051346710.074
actin filament organizationGO:00070151130.074
response to growth factorGO:00708481980.073
amine metabolic processGO:0009308450.073
regulation of interleukin 8 productionGO:003267730.073
bone mineralizationGO:0030282540.073
dna metabolic processGO:00062593030.073
forebrain developmentGO:00309003020.073
regulation of b cell mediated immunityGO:0002712370.072
response to alcoholGO:0097305480.072
hypersensitivityGO:0002524100.072
purine nucleoside biosynthetic processGO:0042451190.071
positive regulation of phosphatase activityGO:001092240.071
granulocyte activationGO:0036230100.071
positive regulation of intracellular protein transportGO:0090316420.070
regulation of mapk cascadeGO:00434082480.070
Mouse
defense response to fungusGO:0050832120.070
positive regulation of b cell activationGO:0050871490.070
Mouse
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.070
tumor necrosis factor biosynthetic processGO:0042533100.070
negative regulation of angiogenesisGO:0016525250.070
leukotriene metabolic processGO:000669170.070
lipid transportGO:0006869980.070
regulation of interleukin 6 biosynthetic processGO:0045408110.069
Mouse

Tlr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.788
disease of anatomical entityDOID:700.788
eye and adnexa diseaseDOID:149200.788
nervous system diseaseDOID:86300.788
eye diseaseDOID:561400.788
retinal diseaseDOID:567900.703
retinal degenerationDOID:846600.703
degeneration of macula and posterior poleDOID:200700.703
macular degenerationDOID:444800.703
age related macular degenerationDOID:1087100.703
disease of metabolismDOID:001466700.181
nutrition diseaseDOID:37400.181
acquired metabolic diseaseDOID:006015800.181